CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: amiodarone
Accession: CHEBI:2663
browse the term
Definition: A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Synonyms: exact_synonym: (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
related_synonym: 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran; 2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone; 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran; Formula=C25H29I2NO3; InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3; InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N; SMILES=CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1; amiodarona; amiodaronum
xref: Beilstein:1271711; CAS:1951-25-3; DrugBank:DB01118; Drug_Central:176; HMDB:HMDB0015250; KEGG:C06823; KEGG:D02910; LINCS:LSM-2379
xref_mesh: MESH:D000638
xref: PMID:10188629; PMID:16479044; PMID:18368867; Patent:CA2826272; Patent:TW201400111; Wikipedia:Amiodarone
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Aadat
aminoadipate aminotransferase
affects expression
EXP
Amiodarone affects the expression of AADAT mRNA
CTD
PMID:18355885
NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
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Abca1
ATP binding cassette subfamily A member 1
decreases expression
ISO
Amiodarone results in decreased expression of ABCA1 mRNA
CTD
PMID:29248575
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abca2
ATP binding cassette subfamily A member 2
increases expression
ISO
Amiodarone results in increased expression of ABCA2 mRNA
CTD
PMID:19774075
NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
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Abcb11
ATP binding cassette subfamily B member 11
multiple interactions decreases expression decreases activity
ISO EXP
Amiodarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid] Amiodarone results in decreased expression of ABCB11 mRNA Amiodarone results in decreased activity of ABCB11 protein
CTD
PMID:20829430 PMID:24014644 PMID:27765674
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1a
ATP binding cassette subfamily B member 1A
multiple interactions affects expression affects response to substance decreases activity
ISO EXP
Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin] Amiodarone affects the expression of ABCB1 mRNA; Amiodarone affects the expression of ABCB1A mRNA Amiodarone inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon] ABCB1A protein affects the susceptibility to Amiodarone Amiodarone results in decreased activity of ABCB1 protein
CTD
PMID:11231118 PMID:12235267 PMID:15502009 PMID:18355885 PMID:19483382
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcb1b
ATP-binding cassette, sub-family B member 1B
affects response to substance
ISO
ABCB1B protein affects the susceptibility to Amiodarone
CTD
PMID:15502009
NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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Abcb4
ATP binding cassette subfamily B member 4
increases expression decreases expression
ISO EXP
Amiodarone results in increased expression of ABCB4 mRNA Amiodarone results in decreased expression of ABCB4 mRNA
CTD
PMID:24489787 PMID:27765674
NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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Abcc2
ATP binding cassette subfamily C member 2
increases expression
EXP
Amiodarone results in increased expression of ABCC2 mRNA
CTD
PMID:27765674
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Abcc3
ATP binding cassette subfamily C member 3
increases expression decreases expression
ISO EXP
Amiodarone results in increased expression of ABCC3 mRNA Amiodarone results in decreased expression of ABCC3 mRNA
CTD
PMID:24489787 PMID:27765674
NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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Abcc4
ATP binding cassette subfamily C member 4
decreases expression
EXP
Amiodarone results in decreased expression of ABCC4 mRNA
CTD
PMID:27765674
NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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Abcc6
ATP binding cassette subfamily C member 6
affects expression
EXP
Amiodarone affects the expression of ABCC6 mRNA
CTD
PMID:19483382
NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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Abcd3
ATP binding cassette subfamily D member 3
increases expression
ISO
Amiodarone results in increased expression of ABCD3 mRNA
CTD
PMID:24489787
NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
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Abcd4
ATP binding cassette subfamily D member 4
increases expression
ISO
Amiodarone results in increased expression of ABCD4 mRNA
CTD
PMID:24489787
NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
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Abcg5
ATP binding cassette subfamily G member 5
affects expression increases expression
EXP
Amiodarone affects the expression of ABCG5 mRNA Amiodarone results in increased expression of ABCG5 mRNA
CTD
PMID:19483382 PMID:27765674
NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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Abhd1
abhydrolase domain containing 1
affects expression
EXP
Amiodarone affects the expression of ABHD1 mRNA
CTD
PMID:19483382
NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
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Abhd14b
abhydrolase domain containing 14b
affects expression
EXP
Amiodarone affects the expression of ABHD14B mRNA
CTD
PMID:19483382
NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
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Abhd17a
abhydrolase domain containing 17A, depalmitoylase
affects expression
EXP
Amiodarone affects the expression of ABHD17A mRNA
CTD
PMID:19483382
NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
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Abl1
ABL proto-oncogene 1, non-receptor tyrosine kinase
increases expression
ISO
Amiodarone results in increased expression of ABL1 mRNA
CTD
PMID:19774075
NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
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Acaa1b
acetyl-Coenzyme A acyltransferase 1B
increases expression
ISO
Amiodarone results in increased expression of ACAA1 mRNA
CTD
PMID:15265979
NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
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Acaca
acetyl-CoA carboxylase alpha
affects expression increases expression
EXP ISO
Amiodarone affects the expression of ACACA mRNA Amiodarone results in increased expression of ACACA mRNA
CTD
PMID:19483382 PMID:19774075
NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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Acacb
acetyl-CoA carboxylase beta
increases expression
EXP ISO
Amiodarone results in increased expression of ACACB mRNA
CTD
PMID:19224547 PMID:24489787
NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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Acad10
acyl-CoA dehydrogenase family, member 10
increases expression
ISO
Amiodarone results in increased expression of ACAD10 mRNA
CTD
PMID:24535564
NCBI chr12:34,901,211...34,943,973
Ensembl chr12:34,901,219...34,982,521
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Acad9
acyl-CoA dehydrogenase family, member 9
increases expression
ISO
Amiodarone results in increased expression of ACAD9 mRNA
CTD
PMID:24489787
NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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Acadl
acyl-CoA dehydrogenase, long chain
affects expression
EXP
Amiodarone affects the expression of ACADL mRNA
CTD
PMID:19483382
NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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Acadm
acyl-CoA dehydrogenase medium chain
increases expression
ISO
Amiodarone results in increased expression of ACADM mRNA
CTD
PMID:24489787
NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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Acat1
acetyl-CoA acetyltransferase 1
increases expression
ISO
Amiodarone results in increased expression of ACAT1 mRNA
CTD
PMID:24489787
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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Acat2
acetyl-CoA acetyltransferase 2
increases expression
EXP
Amiodarone results in increased expression of ACAT2 mRNA
CTD
PMID:32084307
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acer2
alkaline ceramidase 2
increases expression
EXP
Amiodarone results in increased expression of ACER2 mRNA
CTD
PMID:25580480
NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
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Acly
ATP citrate lyase
increases expression
ISO EXP
Amiodarone results in increased expression of ACLY mRNA
CTD
PMID:32084307 PMID:32535746
NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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Aco1
aconitase 1
affects expression
EXP
Amiodarone affects the expression of ACO1 mRNA
CTD
PMID:19483382
NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
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Aco2
aconitase 2
affects expression
EXP
Amiodarone affects the expression of ACO2 mRNA
CTD
PMID:19483382
NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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Acot1
acyl-CoA thioesterase 1
increases expression
ISO EXP
Amiodarone results in increased expression of ACOT1 mRNA
CTD
PMID:24489787 PMID:24535564 PMID:30685923 PMID:32084307
NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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Acot12
acyl-CoA thioesterase 12
affects expression increases expression
EXP ISO
Amiodarone affects the expression of ACOT12 mRNA Amiodarone results in increased expression of ACOT12 mRNA
CTD
PMID:19483382 PMID:24489787
NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
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Acot2
acyl-CoA thioesterase 2
increases expression
ISO
Amiodarone results in increased expression of ACOT2 mRNA
CTD
PMID:24489787 PMID:24535564 PMID:30685923
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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Acot3
acyl-CoA thioesterase 3
increases expression
ISO
Amiodarone results in increased expression of ACOT3 mRNA
CTD
PMID:24535564
NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427 Ensembl chr 6:103,682,596...103,688,427
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Acot4
acyl-CoA thioesterase 4
affects expression
EXP
Amiodarone affects the expression of ACOT4 mRNA
CTD
PMID:19483382
NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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Acot8
acyl-CoA thioesterase 8
increases expression
ISO
Amiodarone results in increased expression of ACOT8 mRNA
CTD
PMID:19774075
NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851
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Acox1
acyl-CoA oxidase 1
increases expression
ISO
Amiodarone results in increased expression of ACOX1 mRNA
CTD
PMID:15265979 PMID:30685923
NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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Acox2
acyl-CoA oxidase 2
increases expression
ISO
Amiodarone results in increased expression of ACOX2 mRNA
CTD
PMID:24489787
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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Acsf3
acyl-CoA synthetase family member 3
increases expression
ISO
Amiodarone results in increased expression of ACSF3 mRNA
CTD
PMID:19774075
NCBI chr19:50,835,116...50,875,557
Ensembl chr19:50,835,221...50,875,553
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Acsl3
acyl-CoA synthetase long-chain family member 3
increases expression
EXP
Amiodarone results in increased expression of ACSL3 mRNA
CTD
PMID:32084307
NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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Acss2
acyl-CoA synthetase short-chain family member 2
increases expression
ISO EXP
Amiodarone results in increased expression of ACSS2 mRNA
CTD
PMID:24535564 PMID:32084307
NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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Acta2
actin alpha 2, smooth muscle
multiple interactions increases expression
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein] Amiodarone results in increased expression of ACTA2 mRNA; Amiodarone results in increased expression of ACTA2 protein
CTD
PMID:31071512
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actr3b
actin related protein 3B
increases expression
ISO
Amiodarone results in increased expression of ACTR3B mRNA
CTD
PMID:19774075
NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441
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Acvr1b
activin A receptor type 1B
increases expression
ISO
Amiodarone results in increased expression of ACVR1B mRNA
CTD
PMID:19774075
NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
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Acyp1
acylphosphatase 1
increases expression
ISO
Amiodarone results in increased expression of ACYP1 mRNA
CTD
PMID:19774075
NCBI chr 6:104,919,162...104,932,348
Ensembl chr 6:104,919,162...104,932,387
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Adam15
ADAM metallopeptidase domain 15
affects expression
EXP
Amiodarone affects the expression of ADAM15 mRNA
CTD
PMID:19483382
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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Add1
adducin 1
affects expression
EXP
Amiodarone affects the expression of ADD1 mRNA
CTD
PMID:19483382
NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
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Adgrd1
adhesion G protein-coupled receptor D1
increases expression
ISO
Amiodarone results in increased expression of ADGRD1 mRNA
CTD
PMID:19774075
NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696
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Adgrf1
adhesion G protein-coupled receptor F1
decreases expression
ISO
Amiodarone results in decreased expression of ADGRF1 mRNA
CTD
PMID:24535564
NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704
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Adh4
alcohol dehydrogenase 4 (class II), pi polypeptide
affects expression
EXP
Amiodarone affects the expression of ADH4 mRNA
CTD
PMID:19483382
NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
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Adm2
adrenomedullin 2
multiple interactions
ISO
ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]]
CTD
PMID:34434487
NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
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Adora3
adenosine A3 receptor
increases expression
ISO
Amiodarone results in increased expression of ADORA3 mRNA
CTD
PMID:19774075
NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
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Adra2a
adrenoceptor alpha 2A
increases expression
ISO
Amiodarone results in increased expression of ADRA2A mRNA
CTD
PMID:19774075
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Adrb1
adrenoceptor beta 1
decreases expression
ISO
Amiodarone results in decreased expression of ADRB1 protein
CTD
PMID:1653643
NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
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Adrb2
adrenoceptor beta 2
decreases expression
ISO
Amiodarone results in decreased expression of ADRB2 protein
CTD
PMID:1653643
NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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Adrb3
adrenoceptor beta 3
multiple interactions
EXP
Amiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein]
CTD
PMID:10217540
NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
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Adtrp
androgen-dependent TFPI-regulating protein
affects expression
EXP
Amiodarone affects the expression of ADTRP mRNA
CTD
PMID:19483382
NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
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Afm
afamin
affects expression
EXP
Amiodarone affects the expression of AFM mRNA
CTD
PMID:19483382
NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870
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Afp
alpha-fetoprotein
increases expression
ISO
Amiodarone results in increased expression of AFP mRNA
CTD
PMID:24489787
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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Agt
angiotensinogen
increases expression affects expression multiple interactions
ISO EXP
Amiodarone results in increased expression of AGT mRNA; Amiodarone results in increased expression of AGT protein Amiodarone affects the expression of AGT mRNA [FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD
PMID:17214612 PMID:19483382
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Agtr1a
angiotensin II receptor, type 1a
affects expression
EXP
Amiodarone affects the expression of AGTR1A mRNA
CTD
PMID:19483382
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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Ahnak
AHNAK nucleoprotein
increases expression
ISO
Amiodarone results in increased expression of AHNAK mRNA
CTD
PMID:19774075
NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
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Ahr
aryl hydrocarbon receptor
affects expression
ISO
Amiodarone affects the expression of AHR mRNA
CTD
PMID:35641671
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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Aifm1
apoptosis inducing factor, mitochondria associated 1
increases expression
ISO
Amiodarone results in increased expression of AIFM1 mRNA
CTD
PMID:24489787
NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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Ak4
adenylate kinase 4
increases expression
EXP
Amiodarone results in increased expression of AK4 protein
CTD
PMID:16538043
NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
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Akr1a1
aldo-keto reductase family 1 member A1
affects expression
EXP
Amiodarone affects the expression of AKR1A1 mRNA
CTD
PMID:19483382
NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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Akr1c1
aldo-keto reductase family 1, member C1
increases expression
ISO
Amiodarone results in increased expression of AKR1C1 mRNA
CTD
PMID:21163907
NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
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Akr7a2
aldo-keto reductase family 7, member A2
affects expression
EXP
Amiodarone affects the expression of AKR7A2 mRNA
CTD
PMID:19483382
NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
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Akr7a3
aldo-keto reductase family 7 member A3
affects expression
EXP
Amiodarone affects the expression of AKR7A3 mRNA
CTD
PMID:19483382
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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Akt1
AKT serine/threonine kinase 1
decreases phosphorylation
ISO
Amiodarone results in decreased phosphorylation of AKT1 protein
CTD
PMID:23912912 PMID:26515726
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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Alas1
5'-aminolevulinate synthase 1
increases expression
ISO
Amiodarone results in increased expression of ALAS1 mRNA
CTD
PMID:19774075
NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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Alas2
5'-aminolevulinate synthase 2
decreases expression
ISO
Amiodarone results in decreased expression of ALAS2 mRNA
CTD
PMID:24535564
NCBI chr X:19,463,146...19,486,526
Ensembl chr X:19,463,171...19,486,519
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Alb
albumin
increases expression
ISO
Amiodarone results in increased expression of ALB mRNA
CTD
PMID:19774075 PMID:36586010
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
affects expression
EXP
Amiodarone affects the expression of ALDH1A1 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Aldh2
aldehyde dehydrogenase 2 family member
affects expression
EXP
Amiodarone affects the expression of ALDH2 mRNA
CTD
PMID:19483382
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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Aldh3a2
aldehyde dehydrogenase 3 family, member A2
increases expression
ISO
Amiodarone results in increased expression of ALDH3A2 mRNA
CTD
PMID:24535564
NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
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Aldh6a1
aldehyde dehydrogenase 6 family, member A1
increases expression
EXP
Amiodarone results in increased expression of ALDH6A1 mRNA
CTD
PMID:17991464
NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
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Alg12
ALG12, alpha-1,6-mannosyltransferase
increases expression
ISO
Amiodarone results in increased expression of ALG12 mRNA
CTD
PMID:19774075
NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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Alg2
ALG2, alpha-1,3/1,6-mannosyltransferase
increases expression
ISO
Amiodarone results in increased expression of ALG2 mRNA
CTD
PMID:19774075
NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297
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Alk
ALK receptor tyrosine kinase
increases expression
ISO
Amiodarone results in increased expression of ALK mRNA
CTD
PMID:19774075
NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
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Alkal1
ALK and LTK ligand 1
increases expression
ISO
Amiodarone results in increased expression of ALKAL1 mRNA
CTD
PMID:19774075
NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948
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Alkbh7
alkB homolog 7
affects expression
EXP
Amiodarone affects the expression of ALKBH7 mRNA
CTD
PMID:19483382
NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
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Amigo1
adhesion molecule with Ig like domain 1
increases expression
ISO
Amiodarone results in increased expression of AMIGO1 mRNA
CTD
PMID:19774075
NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585
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Angptl3
angiopoietin-like 3
decreases expression
ISO
Amiodarone results in decreased expression of ANGPTL3 mRNA
CTD
PMID:27089845
NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
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Angptl4
angiopoietin-like 4
increases expression
ISO
Amiodarone results in increased expression of ANGPTL4 mRNA
CTD
PMID:24489787
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Anxa4
annexin A4
increases expression
ISO
Amiodarone results in increased expression of ANXA4 mRNA
CTD
PMID:19774075
NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
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Ap1s1
adaptor related protein complex 1 subunit sigma 1
decreases expression increases expression
ISO
Amiodarone results in decreased expression of AP1S1 mRNA Amiodarone results in increased expression of AP1S1 mRNA
CTD
PMID:17175557 PMID:17567588 PMID:29248575
NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
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Ap2m1
adaptor related protein complex 2 subunit mu 1
affects expression
EXP
Amiodarone affects the expression of AP2M1 mRNA
CTD
PMID:19483382
NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
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Apcs
amyloid P component, serum
affects expression
EXP
Amiodarone affects the expression of APCS mRNA
CTD
PMID:19483382
NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
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Apoa4
apolipoprotein A4
affects expression
EXP
Amiodarone affects the expression of APOA4 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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Apoa5
apolipoprotein A5
increases expression
ISO
Amiodarone results in increased expression of APOA5 mRNA
CTD
PMID:24489787
NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
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Apob
apolipoprotein B
decreases expression
ISO
Amiodarone results in decreased expression of APOB mRNA
CTD
PMID:29248575
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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Apoc2
apolipoprotein C2
increases expression
ISO
Amiodarone results in increased expression of APOC2 mRNA
CTD
PMID:24489787
NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
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Apoe
apolipoprotein E
decreases expression
EXP
Amiodarone results in decreased expression of APOE mRNA
CTD
PMID:17991464
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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Apoh
apolipoprotein H
affects expression
EXP
Amiodarone affects the expression of APOH mRNA
CTD
PMID:19483382
NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
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Apool
apolipoprotein O-like
affects expression
EXP
Amiodarone affects the expression of APOOL mRNA
CTD
PMID:19483382
NCBI chr X:77,377,723...77,443,672
Ensembl chr X:77,377,781...77,443,900
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Arc
activity-regulated cytoskeleton-associated protein
increases expression
ISO
Amiodarone results in increased expression of ARC mRNA
CTD
PMID:19774075
NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
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Arg1
arginase 1
affects expression
EXP
Amiodarone affects the expression of ARG1 mRNA
CTD
PMID:19483382
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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Arhgap15
Rho GTPase activating protein 15
increases expression
ISO
Amiodarone results in increased expression of ARHGAP15 mRNA
CTD
PMID:19774075
NCBI chr 3:27,989,368...28,592,722
Ensembl chr 3:27,989,633...28,600,265
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Arhgap35
Rho GTPase activating protein 35
increases expression
ISO
Amiodarone results in increased expression of ARHGAP35 mRNA
CTD
PMID:19774075
NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298
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Arhgap4
Rho GTPase activating protein 4
increases expression
ISO
Amiodarone results in increased expression of ARHGAP4 mRNA
CTD
PMID:19774075
NCBI chr X:151,636,071...151,651,528
Ensembl chr X:151,632,454...151,651,128
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Arhgap45
Rho GTPase activating protein 45
increases expression
ISO
Amiodarone results in increased expression of ARHGAP45 mRNA
CTD
PMID:19774075
NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
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Arhgap9
Rho GTPase activating protein 9
increases expression
ISO
Amiodarone results in increased expression of ARHGAP9 mRNA
CTD
PMID:19774075
NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
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Arhgef10l
Rho guanine nucleotide exchange factor 10 like
increases expression
ISO
Amiodarone results in increased expression of ARHGEF10L mRNA
CTD
PMID:19774075
NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538
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Arhgef7
Rho guanine nucleotide exchange factor 7
increases expression
ISO
Amiodarone results in increased expression of ARHGEF7 mRNA
CTD
PMID:19774075
NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697
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Arhgef9
Cdc42 guanine nucleotide exchange factor 9
increases expression
ISO
Amiodarone results in increased expression of ARHGEF9 mRNA
CTD
PMID:19774075
NCBI chr X:59,919,560...60,077,538
Ensembl chr X:59,920,870...60,077,513
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Arid5a
AT-rich interaction domain 5A
increases expression
ISO
Amiodarone results in increased expression of ARID5A mRNA
CTD
PMID:19774075
NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
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Arl6ip1
ADP-ribosylation factor like GTPase 6 interacting protein 1
affects expression
EXP
Amiodarone affects the expression of ARL6IP1 mRNA
CTD
PMID:19483382
NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
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Armc9
armadillo repeat containing 9
increases expression
ISO
Amiodarone results in increased expression of ARMC9 mRNA
CTD
PMID:19774075
NCBI chr 9:86,802,791...86,928,611
Ensembl chr 9:86,802,868...86,928,860
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Arpc4
actin related protein 2/3 complex, subunit 4
increases expression
ISO
Amiodarone results in increased expression of ARPC4 mRNA
CTD
PMID:19774075
NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
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Asah1
N-acylsphingosine amidohydrolase 1
increases expression
EXP ISO
Amiodarone results in increased expression of ASAH1 mRNA
CTD
PMID:15342952 PMID:17567588 PMID:19224547
NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
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Asb7
ankyrin repeat and SOCS box-containing 7
increases expression
ISO
Amiodarone results in increased expression of ASB7 mRNA
CTD
PMID:19774075
NCBI chr 1:120,222,835...120,267,411
Ensembl chr 1:120,222,745...120,267,282
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Asgr2
asialoglycoprotein receptor 2
affects expression
EXP
Amiodarone affects the expression of ASGR2 mRNA
CTD
PMID:19483382
NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
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Asns
asparagine synthetase (glutamine-hydrolyzing)
increases expression
ISO
Amiodarone results in increased expression of ASNS mRNA
CTD
PMID:17175557 PMID:17567588 PMID:36586010
NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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Atf3
activating transcription factor 3
increases expression multiple interactions
ISO
Amiodarone results in increased expression of ATF3 mRNA 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone promotes the reaction [Amiodarone results in increased expression of ATF3 mRNA]
CTD
PMID:19774075 PMID:34259586 PMID:36586010
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atf4
activating transcription factor 4
increases expression decreases expression multiple interactions
ISO
Amiodarone results in increased expression of ATF4 mRNA; Amiodarone results in increased expression of ATF4 protein Amiodarone results in decreased expression of ATF4 mRNA 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of ATF4 mRNA]
CTD
PMID:21292685 PMID:28962527 PMID:34259586 PMID:35641671 PMID:36586010
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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Atf5
activating transcription factor 5
affects expression
EXP
Amiodarone affects the expression of ATF5 mRNA
CTD
PMID:19483382
NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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Atf6
activating transcription factor 6
multiple interactions
ISO
Amiodarone results in increased expression of and affects the localization of ATF6 protein
CTD
PMID:28962527
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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Atf6b
activating transcription factor 6 beta
increases expression
ISO
Amiodarone results in increased expression of ATF6B mRNA
CTD
PMID:19774075
NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894
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Atg5
autophagy related 5
affects response to substance
ISO
ATG5 protein affects the susceptibility to Amiodarone
CTD
PMID:32651653
NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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Atg7
autophagy related 7
increases expression affects response to substance multiple interactions
ISO
Amiodarone results in increased expression of ATG7 protein ATG7 protein affects the susceptibility to Amiodarone ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]
CTD
PMID:23912912 PMID:32651653
NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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Atoh1
atonal bHLH transcription factor 1
increases expression
ISO
Amiodarone results in increased expression of ATOH1 mRNA
CTD
PMID:19774075
NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
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Atp11c
ATPase phospholipid transporting 11C
increases expression
ISO
Amiodarone results in increased expression of ATP11C mRNA
CTD
PMID:19774075
NCBI chr X:138,564,459...138,752,116
Ensembl chr X:138,565,836...138,751,204
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Atp1a1
ATPase Na+/K+ transporting subunit alpha 1
decreases expression
EXP
Amiodarone results in decreased expression of ATP1A1 protein
CTD
PMID:8071999
NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
decreases expression
EXP
Amiodarone results in decreased expression of ATP1A2 mRNA; Amiodarone results in decreased expression of ATP1A2 protein
CTD
PMID:7573397 PMID:8071999 PMID:12479229
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
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Atp1b1
ATPase Na+/K+ transporting subunit beta 1
decreases expression
EXP
Amiodarone results in decreased expression of ATP1B1 protein
CTD
PMID:8071999
NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
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Atp1b2
ATPase Na+/K+ transporting subunit beta 2
decreases expression
EXP
Amiodarone results in decreased expression of ATP1B2 mRNA
CTD
PMID:8071999
NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
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Atp2a2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2
decreases expression
EXP
Amiodarone results in decreased expression of ATP2A2 mRNA
CTD
PMID:17535870
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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Atp5f1b
ATP synthase F1 subunit beta
increases expression
EXP
Amiodarone results in increased expression of ATP5F1B mRNA
CTD
PMID:17991464
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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Atp5f1e
ATP synthase F1 subunit epsilon
affects expression
EXP
Amiodarone affects the expression of ATP5F1E mRNA
CTD
PMID:19483382
NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
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Atp6ap2
ATPase H+ transporting accessory protein 2
affects expression
EXP
Amiodarone affects the expression of ATP6AP2 mRNA
CTD
PMID:19483382
NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
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Atp6v1a
ATPase H+ transporting V1 subunit A
affects expression
EXP
Amiodarone affects the expression of ATP6V1A mRNA
CTD
PMID:19483382
NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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Atp6v1f
ATPase H+ transporting V1 subunit F
affects expression
EXP
Amiodarone affects the expression of ATP6V1F mRNA
CTD
PMID:19483382
NCBI chr 4:58,067,666...58,070,628
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Baat
bile acid CoA:amino acid N-acyltransferase
affects expression
EXP
Amiodarone affects the expression of BAAT mRNA
CTD
PMID:19483382
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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Bag1
BAG cochaperone 1
increases expression
ISO
Amiodarone results in increased expression of BAG1 mRNA
CTD
PMID:19774075
NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
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Bag3
BAG cochaperone 3
decreases expression
EXP
Amiodarone results in decreased expression of BAG3 mRNA
CTD
PMID:17991464
NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
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Baiap2l1
BAR/IMD domain containing adaptor protein 2 like 1
increases expression
ISO
Amiodarone results in increased expression of BAIAP2L1 mRNA
CTD
PMID:19774075
NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
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Bax
BCL2 associated X, apoptosis regulator
increases expression multiple interactions
ISO
Amiodarone results in increased expression of BAX mRNA; Amiodarone results in increased expression of BAX protein ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]
CTD
PMID:12084619 PMID:34434487
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bbc3
Bcl-2 binding component 3
increases expression
ISO
Amiodarone results in increased expression of BBC3 mRNA
CTD
PMID:36586010
NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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Bbox1
gamma-butyrobetaine hydroxylase 1
increases expression
ISO
Amiodarone results in increased expression of BBOX1 mRNA
CTD
PMID:19774075
NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
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Bckdha
branched chain keto acid dehydrogenase E1 subunit alpha
increases expression
EXP
Amiodarone results in increased expression of BCKDHA protein
CTD
PMID:16538043
NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
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Bcl2
BCL2, apoptosis regulator
decreases expression multiple interactions
EXP ISO
Amiodarone results in decreased expression of BCL2 protein Amiodarone results in decreased expression of BCL2 mRNA; Amiodarone results in decreased expression of BCL2 protein [3-methyladenine co-treated with Amiodarone] results in decreased expression of BCL2 protein; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]
CTD
PMID:21224497 PMID:23912912 PMID:34434487
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l11
Bcl2-like 11
increases expression
ISO
Amiodarone results in increased expression of BCL2L11 mRNA
CTD
PMID:19774075
NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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Bcl3
BCL3, transcription coactivator
increases expression
EXP
Amiodarone results in increased expression of BCL3 mRNA
CTD
PMID:22015988
NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
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Bcl6b
BCL6B, transcription repressor
affects expression
EXP
Amiodarone affects the expression of BCL6B mRNA
CTD
PMID:19483382
NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
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Bco1
beta-carotene oxygenase 1
decreases expression
ISO
Amiodarone results in decreased expression of BCO1 mRNA
CTD
PMID:24535564
NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
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Bdnf
brain-derived neurotrophic factor
affects expression
EXP
Amiodarone affects the expression of BDNF mRNA
CTD
PMID:31324950
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Bhlhe40
basic helix-loop-helix family, member e40
increases expression
ISO
Amiodarone results in increased expression of BHLHE40 mRNA
CTD
PMID:19774075
NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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Bhmt
betaine-homocysteine S-methyltransferase
affects expression
EXP
Amiodarone affects the expression of BHMT mRNA
CTD
PMID:18355885
NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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Bid
BH3 interacting domain death agonist
multiple interactions
ISO
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein
CTD
PMID:21292685
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Birc5
baculoviral IAP repeat-containing 5
decreases expression
EXP
Amiodarone results in decreased expression of BIRC5 protein
CTD
PMID:21224497
NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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Bltp3b
bridge-like lipid transfer protein family member 3B
affects expression
EXP
Amiodarone affects the expression of BLTP3B mRNA
CTD
PMID:19483382
NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720
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Bmf
Bcl2 modifying factor
affects expression
EXP
Amiodarone affects the expression of BMF mRNA
CTD
PMID:19483382
NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
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Bmp2k
BMP-2 inducible kinase
increases expression
ISO
Amiodarone results in increased expression of BMP2K mRNA
CTD
PMID:19774075
NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
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Bnip3
BCL2 interacting protein 3
affects expression
EXP
Amiodarone affects the expression of BNIP3 mRNA
CTD
PMID:19483382
NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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Bola2
bolA family member 2
increases expression
ISO
Amiodarone results in increased expression of BOLA2 mRNA
CTD
PMID:19774075
NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676
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Boll
boule homolog, RNA binding protein
increases expression
ISO
Amiodarone results in increased expression of BOLL mRNA
CTD
PMID:19774075
NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916
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Brca1
BRCA1, DNA repair associated
increases expression
ISO
Amiodarone results in increased expression of BRCA1 mRNA
CTD
PMID:24489787
NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
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Brcc3
BRCA1/BRCA2-containing complex subunit 3
increases expression
ISO
Amiodarone results in increased expression of BRCC3 mRNA
CTD
PMID:19774075
NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
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Brpf1
bromodomain and PHD finger containing, 1
increases expression
ISO
Amiodarone results in increased expression of BRPF1 mRNA
CTD
PMID:19774075
NCBI chr 4:146,456,325...146,472,781
Ensembl chr 4:146,456,318...146,472,649
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Bsg
basigin
increases expression
ISO
Amiodarone results in increased expression of BSG mRNA
CTD
PMID:19774075
NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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Btf3
basic transcription factor 3
affects expression
EXP
Amiodarone affects the expression of BTF3 mRNA
CTD
PMID:19483382
NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
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C11h21orf91
similar to human chromosome 21 open reading frame 91
increases expression
ISO
Amiodarone results in increased expression of C21ORF91 mRNA
CTD
PMID:19774075
NCBI chr11:17,229,129...17,262,307
Ensembl chr11:17,229,138...17,262,483
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C19h16orf74
similar to human chromosome 16 open reading frame 74
increases expression
ISO
Amiodarone results in increased expression of C16ORF74 mRNA
CTD
PMID:19774075
NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349
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C1h11orf16
similar to human chromosome 11 open reading frame 16
increases expression
ISO
Amiodarone results in increased expression of C11ORF16 mRNA
CTD
PMID:19774075
NCBI chr 1:163,742,987...163,754,920
Ensembl chr 1:163,743,021...163,754,089
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C1qbp
complement C1q binding protein
affects expression
EXP
Amiodarone affects the expression of C1QBP mRNA
CTD
PMID:19483382
NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
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C1s
complement C1s
affects expression
EXP
Amiodarone affects the expression of C1S mRNA
CTD
PMID:19483382
NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
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C2cd2
C2 calcium-dependent domain containing 2
affects expression
EXP
Amiodarone affects the expression of C2CD2 mRNA
CTD
PMID:19483382
NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
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C2cd4b
C2 calcium-dependent domain containing 4B
increases expression
ISO
Amiodarone results in increased expression of NLF2 mRNA
CTD
PMID:19774075
NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
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C2h3orf33
similar to human chromosome 3 open reading frame 33
increases expression
ISO
Amiodarone results in increased expression of C3ORF33 mRNA
CTD
PMID:19774075
NCBI chr 2:148,376,598...148,404,343
Ensembl chr 2:148,380,581...148,404,387
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C4bpa
complement component 4 binding protein, alpha
affects expression
EXP
Amiodarone affects the expression of C4BPA mRNA
CTD
PMID:19483382
NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
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C7
complement C7
affects expression
EXP
Amiodarone affects the expression of C7 mRNA
CTD
PMID:19483382
NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
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C8b
complement C8 beta chain
affects expression decreases expression
EXP ISO
Amiodarone affects the expression of C8B mRNA Amiodarone results in decreased expression of C8B mRNA
CTD
PMID:19483382 PMID:24535564
NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
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C8h3orf18
similar to human chromosome 3 open reading frame 18
increases expression
ISO
Amiodarone results in increased expression of C3ORF18 mRNA
CTD
PMID:19774075
NCBI chr 8:108,012,638...108,022,050
Ensembl chr 8:108,012,638...108,022,461
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C9h6orf141
similar to human chromosome 6 open reading frame 141
increases expression
ISO
Amiodarone results in increased expression of C6ORF141 mRNA
CTD
PMID:19774075
NCBI chr 9:20,024,916...20,029,094
Ensembl chr 9:20,024,916...20,029,094
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Cacna1c
calcium voltage-gated channel subunit alpha1 C
decreases expression
ISO
Amiodarone results in decreased expression of CACNA1C mRNA
CTD
PMID:15520326
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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Cadps2
calcium dependent secretion activator 2
affects expression
EXP
Amiodarone affects the expression of CADPS2 mRNA
CTD
PMID:19483382
NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
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Calr
calreticulin
increases expression
ISO
Amiodarone results in increased expression of CALR mRNA
CTD
PMID:36586010
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
increases expression
ISO
Amiodarone results in increased expression of CAMK2A mRNA
CTD
PMID:19774075
NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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Capn11
calpain 11
increases expression
ISO
Amiodarone results in increased expression of CAPN11 mRNA
CTD
PMID:19774075
NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601
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Capn3
calpain 3
increases expression
ISO
Amiodarone results in increased expression of CAPN3 mRNA
CTD
PMID:19774075
NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
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Caprin1
cell cycle associated protein 1
affects expression
EXP
Amiodarone affects the expression of CAPRIN1 mRNA
CTD
PMID:19483382
NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
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Car2
carbonic anhydrase 2
affects expression
EXP
Amiodarone affects the expression of CA2 mRNA
CTD
PMID:19483382
NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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Car3
carbonic anhydrase 3
affects expression increases expression
EXP
Amiodarone affects the expression of CAR3 mRNA Amiodarone results in increased expression of CAR3 protein
CTD
PMID:16538043 PMID:19483382
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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Card9
caspase recruitment domain family, member 9
increases expression
ISO
Amiodarone results in increased expression of CARD9 mRNA
CTD
PMID:19774075
NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
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Caskin2
cask-interacting protein 2
increases expression
ISO
Amiodarone results in increased expression of CASKIN2 mRNA
CTD
PMID:19774075
NCBI chr10:101,027,196...101,041,429
Ensembl chr10:101,027,260...101,041,414
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Casp3
caspase 3
affects expression increases cleavage increases activity increases expression decreases expression multiple interactions
EXP ISO
Amiodarone affects the expression of CASP3 mRNA Amiodarone results in increased cleavage of CASP3 protein Amiodarone results in increased activity of CASP3 protein Amiodarone results in increased expression of CASP3 mRNA Amiodarone results in decreased expression of CASP3 protein modified form 3-methyladenine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP3 protein; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; Amiodarone results in increased activity of and results in increased cleavage of CASP3 protein; ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein] Amiodarone results in increased expression of CASP3 mRNA; Amiodarone results in increased expression of CASP3 protein
CTD
PMID:12084619 PMID:12747577 PMID:19483382 PMID:19815060 PMID:21224497 PMID:21292685 PMID:23042730 PMID:23135547 PMID:23912912 PMID:28526448 PMID:32651653 PMID:34434487 More...
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp7
caspase 7
multiple interactions increases expression increases activity
ISO
alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein] Amiodarone results in increased expression of CASP7 mRNA
CTD
PMID:23042730 PMID:23135547 PMID:24489787
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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Casp8
caspase 8
multiple interactions increases expression
ISO EXP
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein Amiodarone results in increased expression of CASP8 protein modified form
CTD
PMID:21224497 PMID:21292685
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
increases expression multiple interactions
ISO
Amiodarone results in increased expression of CASP9 mRNA [Amiodarone co-treated with TNF protein] results in increased activity of CASP9 protein [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP9 protein
CTD
PMID:19774075 PMID:21292685 PMID:23042730
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
multiple interactions decreases activity decreases expression
EXP ISO
Amiodarone inhibits the reaction [Indomethacin results in increased activity of CAT protein] Amiodarone results in decreased activity of CAT protein Amiodarone results in decreased expression of CAT mRNA ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]
CTD
PMID:18087811 PMID:34434487
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cav3
caveolin 3
increases expression
ISO
Amiodarone results in increased expression of CAV3 mRNA
CTD
PMID:19774075
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
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Cbr1
carbonyl reductase 1
affects expression
EXP
Amiodarone affects the expression of CBR1 mRNA
CTD
PMID:19483382
NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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Ccdc134
coiled-coil domain containing 134
increases expression
ISO
Amiodarone results in increased expression of CCDC134 mRNA
CTD
PMID:19774075
NCBI chr 7:113,644,557...113,659,050
Ensembl chr 7:113,644,639...113,659,050
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Ccdc17
coiled-coil domain containing 17
increases expression
ISO
Amiodarone results in increased expression of CCDC17 mRNA
CTD
PMID:19774075
NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673
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Ccdc9
coiled-coil domain containing 9
increases expression
ISO
Amiodarone results in increased expression of CCDC9 mRNA
CTD
PMID:19774075
NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607
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Ccdc96
coiled-coil domain containing 96
increases expression
ISO
Amiodarone results in increased expression of CFAP184 mRNA
CTD
PMID:19774075
NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
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Ccl2
C-C motif chemokine ligand 2
multiple interactions increases expression
ISO
Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein] [Amiodarone co-treated with Dexamethasone] results in increased expression of CCL2 mRNA Amiodarone results in increased expression of CCL2 mRNA
CTD
PMID:19225199 PMID:23397585 PMID:25900201
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccn2
cellular communication network factor 2
increases expression
EXP
Amiodarone results in increased expression of CCN2 mRNA
CTD
PMID:32909452
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccnt1
cyclin T1
increases expression
ISO
Amiodarone results in increased expression of CCNT1 mRNA
CTD
PMID:19774075
NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
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Ccr9
C-C motif chemokine receptor 9
increases expression
ISO
Amiodarone results in increased expression of CCR9 mRNA
CTD
PMID:19774075
NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
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Cd320
CD320 molecule
increases expression
ISO
Amiodarone results in increased expression of CD320 mRNA
CTD
PMID:19774075
NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976
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Cd36
CD36 molecule
increases expression decreases expression
ISO
Amiodarone results in increased expression of CD36 mRNA; Amiodarone results in increased expression of CD36 protein Amiodarone results in decreased expression of CD36 mRNA
CTD
PMID:24535564 PMID:29248575 PMID:32535746 PMID:34259586
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cd86
CD86 molecule
multiple interactions
ISO
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein
CTD
PMID:22785256
NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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Cda
cytidine deaminase
increases expression
ISO
Amiodarone results in increased expression of CDA mRNA
CTD
PMID:24535564
NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
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Cdc25a
cell division cycle 25A
increases expression
ISO
Amiodarone results in increased expression of CDC25A mRNA
CTD
PMID:19774075
NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
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Cdc42se1
CDC42 small effector 1
increases expression
ISO
Amiodarone results in increased expression of CDC42SE1 mRNA
CTD
PMID:19774075
NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028
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Cdh1
cadherin 1
increases expression multiple interactions
ISO
Amiodarone results in increased expression of CDH1 protein 6-bromoindirubin-3'-oxime inhibits the reaction [Amiodarone results in increased expression of CDH1 protein]
CTD
PMID:26515726
NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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Cdh15
cadherin 15
increases expression
ISO
Amiodarone results in increased expression of CDH15 mRNA
CTD
PMID:19774075
NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
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Cdh2
cadherin 2
decreases expression
ISO
Amiodarone results in decreased expression of CDH2 protein
CTD
PMID:26515726
NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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Cdh26
cadherin 26
increases expression
ISO
Amiodarone results in increased expression of CDH26 mRNA
CTD
PMID:19774075
NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149
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Cdk17
cyclin-dependent kinase 17
increases expression
ISO
Amiodarone results in increased expression of CDK17 mRNA
CTD
PMID:19774075
NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910
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Cdkn2c
cyclin-dependent kinase inhibitor 2C
affects expression
EXP
Amiodarone affects the expression of CDKN2C mRNA
CTD
PMID:18355885
NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
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Cdo1
cysteine dioxygenase type 1
affects expression
EXP
Amiodarone affects the expression of CDO1 mRNA
CTD
PMID:19483382
NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
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Cebpb
CCAAT/enhancer binding protein beta
increases expression
ISO EXP
Amiodarone results in increased expression of CEBPB mRNA
CTD
PMID:19774075 PMID:25580480
NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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Celf6
CUGBP, Elav-like family member 6
increases expression
ISO
Amiodarone results in increased expression of CELF6 mRNA
CTD
PMID:19774075
NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041
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Cept1
choline/ethanolamine phosphotransferase 1
affects expression
EXP
Amiodarone affects the expression of CEPT1 mRNA
CTD
PMID:19483382
NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
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Ces1d
carboxylesterase 1D
increases expression
ISO
Amiodarone results in increased expression of CES1 mRNA
CTD
PMID:21163907
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Ces2h
carboxylesterase 2H
affects expression
EXP
Amiodarone affects the expression of CES2 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
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Cfi
complement factor I
affects expression
EXP
Amiodarone affects the expression of CFI mRNA
CTD
PMID:19483382
NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
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Cflar
CASP8 and FADD-like apoptosis regulator
decreases expression
EXP
Amiodarone results in decreased expression of CFLAR protein
CTD
PMID:21224497
NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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Cga
glycoprotein hormones, alpha polypeptide
increases expression
EXP
Amiodarone results in increased expression of CGA mRNA
CTD
PMID:3427795
NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
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Chac1
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
increases expression
ISO
Amiodarone results in increased expression of CHAC1 mRNA
CTD
PMID:19774075 PMID:36586010
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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Chaf1a
chromatin assembly factor 1 subunit A
decreases expression
EXP
Amiodarone results in decreased expression of CHAF1A mRNA
CTD
PMID:17991464
NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
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Chat
choline O-acetyltransferase
decreases expression
EXP
Amiodarone results in decreased expression of CHAT protein
CTD
PMID:25659768
NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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Chga
chromogranin A
increases expression
ISO
Amiodarone results in increased expression of CHGA mRNA
CTD
PMID:19774075
NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
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Chp1
calcineurin-like EF-hand protein 1
affects expression
EXP
Amiodarone affects the expression of CHP1 mRNA
CTD
PMID:19483382
NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
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Chrnb3
cholinergic receptor nicotinic beta 3 subunit
increases expression
ISO
Amiodarone results in increased expression of CHRNB3 mRNA
CTD
PMID:19774075
NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
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Chst5
carbohydrate sulfotransferase 5
increases expression
ISO
Amiodarone results in increased expression of CHST6 mRNA
CTD
PMID:19774075
NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064
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Cidea
cell death-inducing DFFA-like effector a
multiple interactions increases expression
ISO
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]
CTD
PMID:28962527
NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
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Cidec
cell death-inducing DFFA-like effector c
increases expression multiple interactions
ISO
Amiodarone results in increased expression of CIDEC mRNA; Amiodarone results in increased expression of CIDEC protein 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]
CTD
PMID:28962527
NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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Cimap3
ciliary microtubule associated protein 3
increases expression
ISO
Amiodarone results in increased expression of CIMAP3 mRNA
CTD
PMID:19774075
NCBI chr 2:193,475,785...193,493,092
Ensembl chr 2:193,475,782...193,493,139
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Cisd1
CDGSH iron sulfur domain 1
affects expression
EXP
Amiodarone affects the expression of CISD1 mRNA
CTD
PMID:19483382
NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
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Clcn4
chloride voltage-gated channel 4
affects expression
EXP
Amiodarone affects the expression of CLCN4 mRNA
CTD
PMID:19483382
NCBI chr X:23,729,194...23,795,391
Ensembl chr X:23,729,338...23,793,238
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Clcn5
chloride voltage-gated channel 5
increases expression
ISO
Amiodarone results in increased expression of CLCN5 mRNA
CTD
PMID:19774075
NCBI chr X:15,185,380...15,339,977
Ensembl chr X:15,185,451...15,334,264
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Clcn6
chloride voltage-gated channel 6
increases expression
ISO
Amiodarone results in increased expression of CLCN6 mRNA
CTD
PMID:19774075
NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
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Clpp
caseinolytic mitochondrial matrix peptidase proteolytic subunit
affects expression
EXP
Amiodarone affects the expression of CLPP mRNA
CTD
PMID:19483382
NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
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Clptm1l
CLPTM1-like
affects expression
EXP
Amiodarone affects the expression of CLPTM1L mRNA
CTD
PMID:19483382
NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
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Clpx
caseinolytic mitochondrial matrix peptidase chaperone subunit X
increases expression
ISO
Amiodarone results in increased expression of CLPX mRNA
CTD
PMID:24535564
NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
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Clvs2
clavesin 2
increases expression
ISO
Amiodarone results in increased expression of CLVS2 mRNA
CTD
PMID:19774075
NCBI chr 1:23,735,660...23,842,685
Ensembl chr 1:23,735,272...23,842,692
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Cmbl
carboxymethylenebutenolidase homolog
affects expression increases expression
EXP ISO
Amiodarone affects the expression of CMBL mRNA Amiodarone results in increased expression of CMBL mRNA
CTD
PMID:19483382 PMID:24535564
NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
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Cmpk1
cytidine/uridine monophosphate kinase 1
affects expression
EXP
Amiodarone affects the expression of CMPK1 mRNA
CTD
PMID:19483382
NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
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Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
affects expression
EXP
Amiodarone affects the expression of CMTM6 mRNA
CTD
PMID:18355885
NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033
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Cmtm7
CKLF-like MARVEL transmembrane domain containing 7
increases expression
ISO
Amiodarone results in increased expression of CMTM7 mRNA
CTD
PMID:19774075
NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621
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Cmya5
cardiomyopathy associated 5
increases expression
ISO
Amiodarone results in increased expression of CMYA5 mRNA
CTD
PMID:19774075
NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364
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Cnih3
cornichon family AMPA receptor auxiliary protein 3
increases expression
ISO
Amiodarone results in increased expression of CNIH3 mRNA
CTD
PMID:19774075
NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121
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Cnnm2
cyclin and CBS domain divalent metal cation transport mediator 2
increases expression
ISO
Amiodarone results in increased expression of CNNM2 mRNA
CTD
PMID:19774075
NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286
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Cnot7
CCR4-NOT transcription complex, subunit 7
increases expression
ISO
Amiodarone results in increased expression of CNOT7 mRNA
CTD
PMID:19774075
NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
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Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
increases expression
ISO
Amiodarone results in increased expression of CNP mRNA
CTD
PMID:19774075
NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
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Col11a1
collagen type XI alpha 1 chain
increases expression
ISO
Amiodarone results in increased expression of COL11A1 mRNA
CTD
PMID:19774075
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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Col1a1
collagen type I alpha 1 chain
increases expression
EXP
Amiodarone results in increased expression of COL1A1 mRNA
CTD
PMID:32909452
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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Col27a1
collagen type XXVII alpha 1 chain
increases expression
ISO
Amiodarone results in increased expression of COL27A1 mRNA
CTD
PMID:19774075
NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174
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Col8a2
collagen type VIII alpha 2 chain
increases expression
ISO
Amiodarone results in increased expression of COL8A2 mRNA
CTD
PMID:19774075
NCBI chr 5:138,586,201...138,613,627
Ensembl chr 5:138,585,999...138,612,850
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Copg1
COPI coat complex subunit gamma 1
affects expression
EXP
Amiodarone affects the expression of COPG1 mRNA
CTD
PMID:19483382
NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
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Cops4
COP9 signalosome subunit 4
affects expression
EXP
Amiodarone affects the expression of COPS4 mRNA
CTD
PMID:19483382
NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
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Copz2
COPI coat complex subunit zeta 2
increases expression
ISO
Amiodarone results in increased expression of COPZ2 mRNA
CTD
PMID:24535564
NCBI chr10:81,832,441...81,845,514
Ensembl chr10:81,832,418...81,845,514
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Coq2
coenzyme Q2, polyprenyltransferase
increases expression
ISO
Amiodarone results in increased expression of COQ2 mRNA
CTD
PMID:24489787
NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
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Coq3
coenzyme Q3 methyltransferase
affects expression increases expression
EXP ISO
Amiodarone affects the expression of COQ3 mRNA Amiodarone results in increased expression of COQ3 mRNA
CTD
PMID:19483382 PMID:24489787
NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
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Coro2a
coronin 2A
increases expression
ISO
Amiodarone results in increased expression of CORO2A mRNA
CTD
PMID:19774075
NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035
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Cort
cortistatin
affects expression
EXP
Amiodarone affects the expression of CORT mRNA
CTD
PMID:31324950
NCBI chr 5:159,560,591...159,562,032
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Cox15
cytochrome c oxidase assembly homolog COX15
increases expression
ISO
Amiodarone results in increased expression of COX15 mRNA
CTD
PMID:24489787
NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
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Cox17
cytochrome c oxidase copper chaperone COX17
increases expression
ISO
Amiodarone results in increased expression of COX17 mRNA
CTD
PMID:24489787
NCBI chr11:62,400,733...62,406,507
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Cox4i1
cytochrome c oxidase subunit 4i1
affects expression
EXP
Amiodarone affects the expression of COX4I1 mRNA
CTD
PMID:19483382
NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
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Cox6b2
cytochrome c oxidase subunit 6B2
increases expression
ISO
Amiodarone results in increased expression of COX6B2 mRNA
CTD
PMID:24535564
NCBI chr 1:69,094,009...69,095,312
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Cplx2
complexin 2
increases expression
ISO
Amiodarone results in increased expression of CPLX2 mRNA
CTD
PMID:19774075
NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
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Cpn1
carboxypeptidase N subunit 1
affects expression
EXP
Amiodarone affects the expression of CPN1 mRNA
CTD
PMID:19483382
NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
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Cpped1
calcineurin-like phosphoesterase domain containing 1
affects expression
EXP
Amiodarone affects the expression of CPPED1 mRNA
CTD
PMID:18355885
NCBI chr10:3,701,522...3,821,050
Ensembl chr10:3,701,459...3,821,054
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Cpq
carboxypeptidase Q
affects expression
EXP
Amiodarone affects the expression of CPQ mRNA
CTD
PMID:19483382
NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
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Cpt1a
carnitine palmitoyltransferase 1A
increases expression decreases expression affects expression
ISO EXP
Amiodarone results in increased expression of CPT1A mRNA Amiodarone results in decreased expression of CPT1A mRNA Amiodarone affects the expression of CPT1A mRNA
CTD
PMID:24489787 PMID:29248575 PMID:32084307
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Cpt2
carnitine palmitoyltransferase 2
increases expression decreases expression
ISO EXP
Amiodarone results in increased expression of CPT2 mRNA Amiodarone results in decreased expression of CPT2 mRNA
CTD
PMID:24489787 PMID:30685923 PMID:32084307
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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Crb3
crumbs cell polarity complex component 3
increases expression
ISO
Amiodarone results in increased expression of CRB3 mRNA
CTD
PMID:19774075
NCBI chr 9:1,898,531...1,903,860
Ensembl chr 9:1,896,623...1,903,859
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Crem
cAMP responsive element modulator
affects expression
EXP
Amiodarone affects the expression of CREM mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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Crot
carnitine O-octanoyltransferase
decreases expression
ISO
Amiodarone results in decreased expression of CROT mRNA
CTD
PMID:27089845
NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
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Crp
C-reactive protein
multiple interactions
ISO
Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]; Amiodarone inhibits the reaction [CRP protein results in increased expression of TNF protein]
CTD
PMID:19225199
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Crtc1
CREB regulated transcription coactivator 1
decreases expression
EXP
Amiodarone results in decreased expression of CRTC1 mRNA
CTD
PMID:17991464
NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381
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Csnk2b
casein kinase 2 beta
affects expression
EXP
Amiodarone affects the expression of CSNK2B mRNA
CTD
PMID:19483382
NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
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Csrp1
cysteine and glycine-rich protein 1
affects expression
EXP
Amiodarone affects the expression of CSRP1 mRNA
CTD
PMID:19483382
NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
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Csrp3
cysteine and glycine rich protein 3
increases expression
ISO
Amiodarone results in increased expression of CSRP3 mRNA
CTD
PMID:24535564
NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
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Cst6
cystatin E/M
increases expression
ISO
Amiodarone results in increased expression of CST6 mRNA
CTD
PMID:19774075
NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
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Cst7
cystatin F
increases expression
ISO
Amiodarone results in increased expression of CST7 mRNA
CTD
PMID:19774075
NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
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Ctc1
CST telomere replication complex component 1
increases expression
ISO
Amiodarone results in increased expression of CTC1 mRNA
CTD
PMID:19774075
NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298
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Ctla4
cytotoxic T-lymphocyte-associated protein 4
increases expression
ISO
Amiodarone results in increased expression of CTLA4 mRNA
CTD
PMID:19774075
NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
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Ctnna1
catenin alpha 1
affects expression
EXP
Amiodarone affects the expression of CTNNA1 mRNA
CTD
PMID:19483382
NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
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Ctnnb1
catenin beta 1
multiple interactions
ISO
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]]
CTD
PMID:34434487
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Ctsb
cathepsin B
affects cleavage
ISO
Amiodarone affects the cleavage of CTSB protein
CTD
PMID:25881747
NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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Ctsd
cathepsin D
affects cleavage
ISO
Amiodarone affects the cleavage of CTSD protein
CTD
PMID:25881747
NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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Ctsl
cathepsin L
affects cleavage
ISO
Amiodarone affects the cleavage of CTSL protein
CTD
PMID:25881747
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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Cxcl2
C-X-C motif chemokine ligand 2
multiple interactions
ISO
Amiodarone inhibits the reaction [Dexamethasone results in increased expression of CXCL2 mRNA]
CTD
PMID:25900201
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression decreases activity increases response to substance multiple interactions
EXP ISO
Amiodarone results in increased expression of CYP1A1 mRNA Amiodarone results in decreased activity of CYP1A1 protein CYP1A1 protein results in increased susceptibility to Amiodarone Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD
PMID:19224547 PMID:20362646 PMID:26477383 PMID:32084307 PMID:33814510 PMID:34181028 More...
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity multiple interactions decreases response to substance
ISO
Amiodarone results in decreased activity of CYP1A2 protein [Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin CYP1A2 protein results in decreased susceptibility to Amiodarone
CTD
PMID:16449812 PMID:26477383 PMID:26599973
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
decreases response to substance decreases activity
ISO
CYP1B1 protein results in decreased susceptibility to Amiodarone Amiodarone results in decreased activity of CYP1B1 protein
CTD
PMID:26477383 PMID:33814510
NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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Cyp26a1
cytochrome P450, family 26, subfamily a, polypeptide 1
increases expression
ISO
Amiodarone results in increased expression of CYP26A1 mRNA
CTD
PMID:19774075
NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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Cyp2a1
cytochrome P450, family 2, subfamily a, polypeptide 1
affects expression increases expression
EXP
Amiodarone affects the expression of CYP2A1 mRNA Amiodarone results in increased expression of CYP2A1 mRNA
CTD
PMID:18355885 PMID:19483382 PMID:32084307
NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
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Cyp2b15
cytochrome P450, family 2, subfamily b, polypeptide 15
affects expression
EXP
Amiodarone affects the expression of CYP2B15 mRNA
CTD
PMID:18355885
NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
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Cyp2b2
cytochrome P450, family 2, subfamily b, polypeptide 2
affects expression
EXP
Amiodarone affects the expression of CYP2B2 mRNA
CTD
PMID:19483382
NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
affects expression increases expression decreases response to substance
EXP ISO
Amiodarone affects the expression of CYP2B3 mRNA Amiodarone results in increased expression of CYP2B10 mRNA CYP2B6 protein results in decreased susceptibility to Amiodarone
CTD
PMID:19483382 PMID:24535564 PMID:26477383
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2c11
cytochrome P450, subfamily 2, polypeptide 11
decreases expression decreases response to substance
EXP ISO
Amiodarone results in decreased expression of CYP2C11 mRNA CYP2C18 protein results in decreased susceptibility to Amiodarone
CTD
PMID:26477383 PMID:32084307
NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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Cyp2c6
cytochrome P450, family 2, subfamily C, polypeptide 6
decreases response to substance
ISO
CYP2C19 protein results in decreased susceptibility to Amiodarone
CTD
PMID:26477383
NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
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Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
decreases activity decreases response to substance multiple interactions increases metabolic processing
ISO
Amiodarone results in decreased activity of CYP2C8 protein CYP2C8 protein results in decreased susceptibility to Amiodarone torsemide inhibits the reaction [Amiodarone results in decreased activity of CYP2C8 protein] CYP2C8 protein results in increased metabolism of Amiodarone
CTD
PMID:15304522 PMID:15716363 PMID:26477383
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Cyp2d3
cytochrome P450, family 2, subfamily d, polypeptide 3
affects expression
EXP
Amiodarone affects the expression of CYP2D3 mRNA
CTD
PMID:19483382
NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
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Cyp2d4
cytochrome P450, family 2, subfamily d, polypeptide 4
affects expression multiple interactions increases expression decreases activity
EXP ISO
Amiodarone affects the expression of CYP2D4 mRNA CYP2D6 gene polymorphism affects the reaction [Amiodarone results in increased abundance of Metoprolol] Amiodarone results in increased expression of CYP2D6 mRNA Amiodarone results in decreased activity of CYP2D6 protein
CTD
PMID:15541258 PMID:16449812 PMID:19483382 PMID:19774075
NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
decreases response to substance
ISO
CYP2E1 protein results in decreased susceptibility to Amiodarone
CTD
PMID:26477383
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp2f4
cytochrome P450, family 2, subfamily f, polypeptide 4
affects expression
EXP
Amiodarone affects the expression of CYP2F4 mRNA
CTD
PMID:19483382
NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
increases expression affects expression
ISO EXP
Amiodarone results in increased expression of CYP2J2 mRNA Amiodarone affects the expression of CYP2J4 mRNA
CTD
PMID:19483382 PMID:19774075
NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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Cyp2r1
cytochrome P450, family 2, subfamily r, polypeptide 1
increases expression
ISO
Amiodarone results in increased expression of CYP2R1 mRNA
CTD
PMID:19774075
NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
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Cyp2t1
cytochrome P450, family 2, subfamily t, polypeptide 1
affects expression
EXP
Amiodarone affects the expression of CYP2T1 mRNA
CTD
PMID:19483382
NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
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Cyp2u1
cytochrome P450, family 2, subfamily u, polypeptide 1
decreases expression
ISO
Amiodarone results in decreased expression of CYP2U1 mRNA
CTD
PMID:24535564
NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
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Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
decreases expression
ISO
Amiodarone results in decreased expression of CYP39A1 mRNA
CTD
PMID:24535564
NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
increases expression increases degradation decreases activity multiple interactions increases metabolic processing increases response to substance decreases ethylation
EXP ISO
Amiodarone results in increased expression of CYP3A4 mRNA CYP3A4 protein results in increased degradation of Amiodarone Amiodarone results in decreased activity of CYP3A4 protein [Amiodarone co-treated with Benzoic Acid co-treated with cyproconazole co-treated with flusilazole co-treated with enilconazole co-treated with prochloraz co-treated with propiconazole co-treated with tebuconazole] results in increased expression of CYP3A4 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of CXCL8 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of TNF protein; [CYP3A4 protein results in increased metabolism of Amiodarone] which results in increased abundance of mono-N-desethylamiodarone; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Amiodarone] CYP3A4 protein results in increased susceptibility to Amiodarone CYP3A4 protein results in decreased ethylation of Amiodarone
CTD
PMID:7905403 PMID:8445979 PMID:15304522 PMID:15869686 PMID:16449812 PMID:19224547 PMID:19299527 PMID:21540358 PMID:22652334 PMID:22785256 PMID:26477383 PMID:27485346 PMID:32305697 PMID:34273450 More...
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
affects expression increases expression
EXP
Amiodarone affects the expression of CYP3A23-3A1 mRNA Amiodarone results in increased expression of CYP3A23-3A1 mRNA
CTD
PMID:18355885 PMID:19483382 PMID:32084307
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
affects expression decreases response to substance
EXP ISO
Amiodarone affects the expression of CYP3A9 mRNA CYP3A5 protein results in decreased susceptibility to Amiodarone
CTD
PMID:19483382 PMID:26477383
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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Cyp4a1
cytochrome P450, family 4, subfamily a, polypeptide 1
increases expression
EXP
Amiodarone results in increased expression of CYP4A1 mRNA
CTD
PMID:12883083
NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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Cyp4a8
cytochrome P450, family 4, subfamily a, polypeptide 8
affects expression
EXP
Amiodarone affects the expression of CYP4A8 mRNA
CTD
PMID:19483382
NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
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Cyp4f4
cytochrome P450, family 4, subfamily f, polypeptide 4
affects expression
EXP
Amiodarone affects the expression of CYP4F2 mRNA
CTD
PMID:18355885
NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
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Cyp4f6
cytochrome P450, family 4, subfamily f, polypeptide 6
affects expression
EXP
Amiodarone affects the expression of CYP4F6 mRNA
CTD
PMID:19483382
NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
decreases expression increases expression
EXP
Amiodarone results in decreased expression of CYP7A1 mRNA Amiodarone results in increased expression of CYP7A1 mRNA
CTD
PMID:19224547 PMID:22291062
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Cyp7b1
cytochrome P450 family 7 subfamily B member 1
decreases expression
ISO
Amiodarone results in decreased expression of CYP7B1 mRNA
CTD
PMID:24535564
NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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Dact1
dishevelled-binding antagonist of beta-catenin 1
decreases expression
ISO
Amiodarone results in decreased expression of DACT1 mRNA
CTD
PMID:24535564
NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
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Dapk2
death-associated protein kinase 2
increases expression
ISO
Amiodarone results in increased expression of DAPK2 mRNA
CTD
PMID:19774075
NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
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Dbi
diazepam binding inhibitor
affects expression
EXP
Amiodarone affects the expression of DBI mRNA
CTD
PMID:19483382
NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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Dbn1
drebrin 1
increases expression
ISO
Amiodarone results in increased expression of DBN1 mRNA
CTD
PMID:19774075
NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
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Dbndd1
dysbindin domain containing 1
increases expression
ISO
Amiodarone results in increased expression of DBNDD1 mRNA
CTD
PMID:19774075
NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444
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Dcaf11
DDB1 and CUL4 associated factor 11
affects expression
EXP
Amiodarone affects the expression of DCAF11 mRNA
CTD
PMID:19483382
NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
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Dcaf8
DDB1 and CUL4 associated factor 8
affects expression
EXP
Amiodarone affects the expression of DCAF8 mRNA
CTD
PMID:18355885
NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726
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Dcst2
DC-STAMP domain containing 2
increases expression
ISO
Amiodarone results in increased expression of DCST2 mRNA
CTD
PMID:19774075
NCBI chr 2:174,781,806...174,795,834
Ensembl chr 2:174,781,902...174,795,832
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Dctn1
dynactin subunit 1
increases expression
ISO
Amiodarone results in increased expression of DCTN1 mRNA
CTD
PMID:19774075
NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815
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Dcxr
dicarbonyl and L-xylulose reductase
affects expression
EXP
Amiodarone affects the expression of DCXR mRNA
CTD
PMID:19483382
NCBI chr10:106,006,404...106,008,293
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Ddc
dopa decarboxylase
increases expression
ISO
Amiodarone results in increased expression of DDC mRNA
CTD
PMID:24489787
NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
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Ddit3
DNA-damage inducible transcript 3
increases expression decreases response to substance multiple interactions
ISO
[Amiodarone results in increased expression of DDIT3 mRNA] which results in increased expression of TNFRSF10B mRNA; [Amiodarone results in increased expression of DDIT3 protein] which results in increased expression of TNFRSF10B protein; Amiodarone results in increased expression of DDIT3 mRNA; Amiodarone results in increased expression of DDIT3 protein DDIT3 gene mutant form results in decreased susceptibility to Amiodarone 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; Amiodarone results in increased expression of and affects the localization of DDIT3 protein; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA] 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 protein]; DDIT3 mutant form inhibits the reaction [Amiodarone results in increased expression of TNFRSF10B]; Egtazic Acid inhibits the reaction [Amiodarone results in increased expression of DDIT3]
CTD
PMID:19774075 PMID:21292685 PMID:25295624 PMID:28962527 PMID:32651653 PMID:34259586 PMID:36586010 More...
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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Ddit4
DNA-damage-inducible transcript 4
increases expression
ISO
Amiodarone results in increased expression of DDIT4 mRNA
CTD
PMID:19774075
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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Ddx17
DEAD-box helicase 17
increases expression
ISO
Amiodarone results in increased expression of DDX17 mRNA
CTD
PMID:19774075
NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
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Ddx31
DEAD-box helicase 31
increases expression
ISO
Amiodarone results in increased expression of DDX31 mRNA
CTD
PMID:19774075
NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873
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Ddx39a
DExD-box helicase 39A
increases expression
ISO
Amiodarone results in increased expression of DDX39A mRNA
CTD
PMID:19774075
NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
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Ddx49
DEAD-box helicase 49
increases expression
ISO
Amiodarone results in increased expression of DDX49 mRNA
CTD
PMID:19774075
NCBI chr16:19,125,388...19,133,042
Ensembl chr16:19,125,384...19,133,616
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Decr1
2,4-dienoyl-CoA reductase 1
affects expression
EXP
Amiodarone affects the expression of DECR1 mRNA
CTD
PMID:19483382
NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
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Dedd
death effector domain-containing
increases expression
ISO
Amiodarone results in increased expression of DEDD mRNA
CTD
PMID:19774075
NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332
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Depp1
DEPP autophagy regulator 1
increases expression
ISO
Amiodarone results in increased expression of DEPP1 mRNA
CTD
PMID:17175557
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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Deptor
DEP domain containing MTOR-interacting protein
increases expression
ISO
Amiodarone results in increased expression of DEPTOR mRNA
CTD
PMID:19774075
NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
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Dexi
Dexi homolog
affects expression
EXP
Amiodarone affects the expression of DEXI mRNA
CTD
PMID:19483382
NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
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Dgat1
diacylglycerol O-acyltransferase 1
affects expression increases expression
EXP ISO
Amiodarone affects the expression of DGAT1 mRNA Amiodarone results in increased expression of DGAT1 mRNA
CTD
PMID:19483382 PMID:32651653
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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Dgat2
diacylglycerol O-acyltransferase 2
decreases expression
ISO
Amiodarone results in decreased expression of DGAT2 mRNA
CTD
PMID:28962527
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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Dhcr24
24-dehydrocholesterol reductase
affects expression
EXP
Amiodarone affects the expression of DHCR24 mRNA
CTD
PMID:19483382
NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
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Dhcr7
7-dehydrocholesterol reductase
increases expression
EXP
Amiodarone results in increased expression of DHCR7 mRNA
CTD
PMID:22291062
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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Dhrs2
dehydrogenase/reductase 2
increases expression
ISO
Amiodarone results in increased expression of DHRS2 mRNA
CTD
PMID:19774075
NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
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Dhrs4
dehydrogenase/reductase 4
affects expression
EXP
Amiodarone affects the expression of DHRS4 mRNA
CTD
PMID:19483382
NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
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Dhrs7b
dehydrogenase/reductase 7B
affects expression
EXP
Amiodarone affects the expression of DHRS7B mRNA
CTD
PMID:19483382
NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
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Dhx16
DEAH-box helicase 16
affects expression
EXP
Amiodarone affects the expression of DHX16 mRNA
CTD
PMID:19483382
NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
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Dhx57
DExH-box helicase 57
increases expression
ISO
Amiodarone results in increased expression of DHX57 mRNA
CTD
PMID:19774075
NCBI chr 6:14,725,305...14,776,321
Ensembl chr 6:14,725,303...14,776,321
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Dio1
iodothyronine deiodinase 1
decreases activity
EXP ISO
Amiodarone results in decreased activity of DIO1 protein
CTD
PMID:12538616 PMID:16131326
NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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Dlg4
discs large MAGUK scaffold protein 4
increases expression
ISO
Amiodarone results in increased expression of DLG4 mRNA
CTD
PMID:19774075
NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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Dlk2
delta like non-canonical Notch ligand 2
increases expression
ISO
Amiodarone results in increased expression of DLK2 mRNA
CTD
PMID:19774075
NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594
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Dmac2l
distal membrane arm assembly component 2 like
affects expression
EXP
Amiodarone affects the expression of DMAC2L mRNA
CTD
PMID:19483382
NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
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Dnaaf3
dynein, axonemal, assembly factor 3
increases expression
ISO
Amiodarone results in increased expression of DNAAF3 mRNA
CTD
PMID:19774075
NCBI chr 1:69,291,300...69,299,365
Ensembl chr 1:69,291,454...69,299,344
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Dnah7
dynein, axonemal, heavy chain 7
increases expression
ISO
Amiodarone results in increased expression of DNAH7 mRNA
CTD
PMID:19774075
NCBI chr 9:54,960,235...55,266,529
Ensembl chr 9:54,960,440...55,262,297
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Dnajb11
DnaJ heat shock protein family (Hsp40) member B11
decreases expression
ISO
Amiodarone results in decreased expression of DNAJB11 mRNA
CTD
PMID:24535564
NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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Dnajb12
DnaJ heat shock protein family (Hsp40) member B12
increases expression
ISO
Amiodarone results in increased expression of DNAJB12 mRNA
CTD
PMID:19774075
NCBI chr20:27,828,216...27,846,428
Ensembl chr20:27,828,235...27,846,427
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Dnajb7
DnaJ heat shock protein family (Hsp40) member B7
increases expression
ISO
Amiodarone results in increased expression of DNAJB7 mRNA
CTD
PMID:19774075
NCBI chr 7:112,932,736...112,934,050
Ensembl chr 7:112,932,616...112,945,537
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Dnajb9
DnaJ heat shock protein family (Hsp40) member B9
increases expression multiple interactions
ISO
Amiodarone results in increased expression of DNAJB9 mRNA 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA] Amiodarone results in increased expression of DNAJB9 mRNA; Amiodarone results in increased expression of DNAJB9 protein
CTD
PMID:19774075 PMID:28962527 PMID:34259586 PMID:36586010
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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Dnajc3
DnaJ heat shock protein family (Hsp40) member C3
affects expression increases expression multiple interactions
EXP ISO
Amiodarone affects the expression of DNAJC3 mRNA Amiodarone results in increased expression of DNAJC3 mRNA 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJC3 mRNA]
CTD
PMID:19483382 PMID:28962527 PMID:34259586
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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Dnase1
deoxyribonuclease 1
increases expression
ISO
Amiodarone results in increased expression of DNASE1 mRNA
CTD
PMID:19774075
NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
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Dock5
dedicator of cytokinesis 5
increases expression
ISO
Amiodarone results in increased expression of DOCK5 mRNA
CTD
PMID:19774075
NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
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Dpm2
dolichyl-phosphate mannosyltransferase subunit 2, regulatory
increases expression
ISO
Amiodarone results in increased expression of DPM2 mRNA
CTD
PMID:19774075
NCBI chr 3:15,855,952...15,858,867
Ensembl chr 3:15,856,182...15,869,165 Ensembl chr 3:15,856,182...15,869,165
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Dpp4
dipeptidylpeptidase 4
affects expression
EXP
Amiodarone affects the expression of DPP4 mRNA
CTD
PMID:19483382
NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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Dpyd
dihydropyrimidine dehydrogenase
affects expression
EXP
Amiodarone affects the expression of DPYD mRNA
CTD
PMID:19483382
NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
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Drc7
dynein regulatory complex subunit 7
increases expression
ISO
Amiodarone results in increased expression of DRC7 mRNA
CTD
PMID:19774075
NCBI chr19:9,943,452...9,961,266
Ensembl chr19:9,943,456...9,961,163
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Dusp1
dual specificity phosphatase 1
increases expression
ISO
Amiodarone results in increased expression of DUSP1 mRNA
CTD
PMID:19774075
NCBI chr10:16,680,478...16,683,275
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Dusp10
dual specificity phosphatase 10
increases expression
ISO
Amiodarone results in increased expression of DUSP10 mRNA
CTD
PMID:19774075
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
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Dut
deoxyuridine triphosphatase
increases expression
ISO
Amiodarone results in increased expression of DUT mRNA
CTD
PMID:19774075
NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
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Eaf2
ELL associated factor 2
increases expression
ISO
Amiodarone results in increased expression of EAF2 mRNA
CTD
PMID:19774075
NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
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Ears2
glutamyl-tRNA synthetase 2, mitochondrial
affects expression
EXP
Amiodarone affects the expression of EARS2 mRNA
CTD
PMID:19483382
NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
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Ebp
EBP, cholestenol delta-isomerase
increases expression
EXP
Amiodarone results in increased expression of EBP mRNA
CTD
PMID:22291062
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
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Ech1
enoyl-CoA hydratase 1
increases expression
ISO
Amiodarone results in increased expression of ECH1 mRNA
CTD
PMID:24535564
NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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Echs1
enoyl-CoA hydratase, short chain 1
affects expression
EXP
Amiodarone affects the expression of ECHS1 mRNA
CTD
PMID:19483382
NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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Eci1
enoyl-CoA delta isomerase 1
affects expression
EXP
Amiodarone affects the expression of ECI1 mRNA
CTD
PMID:19483382
NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
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Eci2
enoyl-CoA delta isomerase 2
affects expression
EXP
Amiodarone affects the expression of ECI2 mRNA
CTD
PMID:19483382
NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
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Ecpas
Ecm29 proteasome adaptor and scaffold
decreases expression
EXP
Amiodarone results in decreased expression of ECPAS mRNA
CTD
PMID:17991464
NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860
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Eed
embryonic ectoderm development
increases expression
ISO
Amiodarone results in increased expression of EED mRNA
CTD
PMID:19774075
NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
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Eef1g
eukaryotic translation elongation factor 1 gamma
affects expression
EXP
Amiodarone affects the expression of EEF1G mRNA
CTD
PMID:19483382
NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
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Eepd1
endonuclease/exonuclease/phosphatase family domain containing 1
increases expression
ISO
Amiodarone results in increased expression of EEPD1 mRNA
CTD
PMID:19774075
NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340
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Efcab5
EF-hand calcium binding domain 5
increases expression
ISO
Amiodarone results in increased expression of EFCAB5 mRNA
CTD
PMID:19774075
NCBI chr10:61,926,419...62,042,745
Ensembl chr10:61,926,953...62,042,749
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Efcc1
EF-hand and coiled-coil domain containing 1
increases expression
ISO
Amiodarone results in increased expression of EFCC1 mRNA
CTD
PMID:19774075
NCBI chr 4:120,188,202...120,223,464
Ensembl chr 4:120,188,470...120,217,516
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Egf
epidermal growth factor
multiple interactions
ISO
Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]
CTD
PMID:26515726
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Egfl6
EGF-like-domain, multiple 6
increases expression
ISO
Amiodarone results in increased expression of EGFL6 mRNA
CTD
PMID:19774075
NCBI chr X:27,884,087...27,942,044
Ensembl chr X:27,884,125...27,942,044
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Egfr
epidermal growth factor receptor
decreases expression decreases phosphorylation multiple interactions
ISO
Amiodarone results in decreased expression of EGFR mRNA Amiodarone results in decreased phosphorylation of EGFR protein Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein] Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]
CTD
PMID:24535564 PMID:26515726
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Egr1
early growth response 1
increases expression
ISO
Amiodarone results in increased expression of EGR1 mRNA
CTD
PMID:19774075 PMID:36586010
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
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Egr2
early growth response 2
increases expression
ISO
Amiodarone results in increased expression of EGR2 mRNA
CTD
PMID:19774075
NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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Ehhadh
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
affects expression decreases expression increases expression
EXP ISO
Amiodarone affects the expression of EHHADH mRNA Amiodarone results in decreased expression of EHHADH mRNA Amiodarone results in increased expression of EHHADH mRNA
CTD
PMID:15265979 PMID:19483382 PMID:24489787 PMID:24535564 PMID:27089845
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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Ehmt1
euchromatic histone lysine methyltransferase 1
increases expression
ISO
Amiodarone results in increased expression of EHMT1 mRNA
CTD
PMID:19774075
NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007
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Eif2a
eukaryotic translation initiation factor 2A
increases phosphorylation
ISO
Amiodarone results in increased phosphorylation of EIF2A protein
CTD
PMID:21292685 PMID:28962527
NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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Eif2ak3
eukaryotic translation initiation factor 2 alpha kinase 3
increases expression
ISO
Amiodarone results in increased expression of EIF2AK3 mRNA
CTD
PMID:19774075
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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Eif2s1
eukaryotic translation initiation factor 2 subunit alpha
increases phosphorylation multiple interactions
ISO
Amiodarone results in increased phosphorylation of EIF2S1 protein 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased phosphorylation of EIF2S1 protein]
CTD
PMID:25295624 PMID:32651653 PMID:34259586
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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Eif4a2
eukaryotic translation initiation factor 4A2
affects expression
EXP
Amiodarone affects the expression of EIF4A2 mRNA
CTD
PMID:19483382
NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
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Eif4b
eukaryotic translation initiation factor 4B
affects expression
EXP
Amiodarone affects the expression of EIF4B mRNA
CTD
PMID:18355885
NCBI chr 7:133,206,637...133,228,436
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Eif4e
eukaryotic translation initiation factor 4E
multiple interactions
ISO
Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
CTD
PMID:19771169
NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions decreases phosphorylation affects expression
ISO EXP
Amiodarone inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] Amiodarone results in decreased phosphorylation of EIF4EBP1 protein Amiodarone affects the expression of EIF4EBP1 mRNA
CTD
PMID:19483382 PMID:19771169 PMID:23912912
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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Eif4h
eukaryotic translation initiation factor 4H
affects expression
EXP
Amiodarone affects the expression of EIF4H mRNA
CTD
PMID:19483382
NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
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Eif5
eukaryotic translation initiation factor 5
increases expression
ISO
Amiodarone results in increased expression of EIF5 mRNA
CTD
PMID:19774075
NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
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Elmo3
engulfment and cell motility 3
increases expression
ISO
Amiodarone results in increased expression of ELMO3 mRNA
CTD
PMID:19774075
NCBI chr19:33,181,952...33,186,399
Ensembl chr19:33,182,036...33,186,410
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Elovl6
ELOVL fatty acid elongase 6
increases expression decreases expression
ISO
Amiodarone results in increased expression of ELOVL6 mRNA Amiodarone results in decreased expression of ELOVL6 mRNA; Amiodarone results in decreased expression of ELOVL6 protein
CTD
PMID:24489787 PMID:29248575 PMID:34259586
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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Elp1
elongator acetyltransferase complex subunit 1
increases expression
ISO
Amiodarone results in increased expression of ELP1 mRNA
CTD
PMID:19774075
NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
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Enc1
ectodermal-neural cortex 1
affects expression
EXP
Amiodarone affects the expression of ENC1 mRNA
CTD
PMID:19483382
NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
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Enho
energy homeostasis associated
decreases expression
ISO
Amiodarone results in decreased expression of ENHO mRNA
CTD
PMID:24535564
NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777
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Eno1
enolase 1
affects expression
EXP
Amiodarone affects the expression of ENO1 mRNA
CTD
PMID:19483382
NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
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Enpep
glutamyl aminopeptidase
affects expression
EXP
Amiodarone affects the expression of ENPEP mRNA
CTD
PMID:19483382
NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
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Enpp1
ectonucleotide pyrophosphatase/phosphodiesterase 1
affects expression
EXP
Amiodarone affects the expression of ENPP1 mRNA
CTD
PMID:19483382
NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
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Enpp7
ectonucleotide pyrophosphatase/phosphodiesterase 7
increases expression
ISO
Amiodarone results in increased expression of ENPP7 mRNA
CTD
PMID:19774075
NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589
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Epc1
enhancer of polycomb homolog 1
increases expression
ISO
Amiodarone results in increased expression of EPC1 mRNA
CTD
PMID:19774075
NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425
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Epc2
enhancer of polycomb homolog 2
increases expression
ISO
Amiodarone results in increased expression of EPC2 mRNA
CTD
PMID:19774075
NCBI chr 3:33,867,219...33,967,908
Ensembl chr 3:33,867,219...33,967,150
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Epcam
epithelial cell adhesion molecule
affects expression
EXP
Amiodarone affects the expression of EPCAM mRNA
CTD
PMID:19483382
NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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Ephx1
epoxide hydrolase 1
affects expression
EXP
Amiodarone affects the expression of EPHX1 mRNA
CTD
PMID:18355885
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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Eri2
ERI1 exoribonuclease family member 2
increases expression
ISO
Amiodarone results in increased expression of ERI2 mRNA
CTD
PMID:19774075
NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665
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Ermn
ermin
increases expression
ISO
Amiodarone results in increased expression of ERMN mRNA
CTD
PMID:19774075
NCBI chr 3:42,628,160...42,633,816
Ensembl chr 3:42,626,309...42,633,744
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Ern1
endoplasmic reticulum to nucleus signaling 1
increases phosphorylation
ISO
Amiodarone results in increased phosphorylation of ERN1 protein
CTD
PMID:28962527 PMID:32651653 PMID:34259586
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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Ero1b
endoplasmic reticulum oxidoreductase 1 beta
decreases expression
ISO
Amiodarone results in decreased expression of ERO1B mRNA
CTD
PMID:24535564
NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
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Erp29
endoplasmic reticulum protein 29
affects expression
EXP
Amiodarone affects the expression of ERP29 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
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Esd
esterase D
affects expression
EXP
Amiodarone affects the expression of ESD mRNA
CTD
PMID:19483382
NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
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Etfb
electron transfer flavoprotein subunit beta
affects expression
EXP
Amiodarone affects the expression of ETFB mRNA
CTD
PMID:19483382
NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
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Etfdh
electron transfer flavoprotein dehydrogenase
increases expression
ISO
Amiodarone results in increased expression of ETFDH mRNA
CTD
PMID:24489787
NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745
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Exo1
exonuclease 1
increases expression
ISO
Amiodarone results in increased expression of EXO1 mRNA
CTD
PMID:19774075
NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
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F11
coagulation factor XI
decreases expression
ISO
Amiodarone results in decreased expression of F11 mRNA
CTD
PMID:24535564
NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
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F2
coagulation factor II, thrombin
multiple interactions
ISO
Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein]
CTD
PMID:18974383
NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
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F3
coagulation factor III, tissue factor
multiple interactions decreases activity
ISO
Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 protein] Amiodarone results in decreased activity of F3 protein
CTD
PMID:18974383 PMID:23305835
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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Faah
fatty acid amide hydrolase
affects expression
EXP
Amiodarone affects the expression of FAAH mRNA
CTD
PMID:19483382
NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
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Fabp1
fatty acid binding protein 1
increases expression decreases expression
ISO
Amiodarone results in increased expression of FABP1 mRNA Amiodarone results in decreased expression of FABP1 mRNA
CTD
PMID:15342952 PMID:17567588 PMID:28962527
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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Fabp4
fatty acid binding protein 4
increases expression
ISO
Amiodarone results in increased expression of FABP4 mRNA
CTD
PMID:34259586
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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Fads1
fatty acid desaturase 1
increases expression
EXP
Amiodarone results in increased expression of FADS1 mRNA
CTD
PMID:19224547 PMID:22291062
NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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Fads2
fatty acid desaturase 2
multiple interactions affects expression increases expression
ISO EXP
[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; FADS2 protein affects the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine] Amiodarone affects the expression of FADS2 mRNA
CTD
PMID:19483382 PMID:21123845 PMID:29248575
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
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Fam81a
family with sequence similarity 81, member A
increases expression
ISO
Amiodarone results in increased expression of FAM81A mRNA
CTD
PMID:19774075
NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875
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Fam89a
family with sequence similarity 89, member A
increases expression
ISO
Amiodarone results in increased expression of FAM89A mRNA
CTD
PMID:19774075
NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631
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Fanca
FA complementation group A
increases expression
ISO
Amiodarone results in increased expression of FANCA mRNA
CTD
PMID:19774075
NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527
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Farp2
FERM, ARH/RhoGEF and pleckstrin domain protein 2
increases expression
ISO
Amiodarone results in increased expression of FARP2 mRNA
CTD
PMID:19774075
NCBI chr 9:94,053,650...94,161,982
Ensembl chr 9:94,053,726...94,162,212
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Fasn
fatty acid synthase
increases expression decreases expression affects expression
ISO EXP
Amiodarone results in increased expression of FASN mRNA Amiodarone results in decreased expression of FASN mRNA; Amiodarone results in decreased expression of FASN protein Amiodarone affects the expression of FASN mRNA
CTD
PMID:22291062 PMID:24489787 PMID:29248575 PMID:32084307 PMID:34259586
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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Fbp1
fructose-bisphosphatase 1
affects expression
EXP
Amiodarone affects the expression of FBP1 mRNA
CTD
PMID:19483382
NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
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Fbxo16
F-box protein 16
increases expression
ISO
Amiodarone results in increased expression of FBXO16 mRNA
CTD
PMID:19774075
NCBI chr15:39,492,268...39,541,493
Ensembl chr15:39,492,377...39,541,480
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Fbxo32
F-box protein 32
increases expression
ISO
Amiodarone results in increased expression of FBXO32 mRNA
CTD
PMID:19774075
NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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Fcgr2b
Fc gamma receptor 2B
increases expression
EXP
Amiodarone results in increased expression of FCGR2B mRNA
CTD
PMID:25580480
NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
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Fcrl2
Fc receptor-like 2
increases expression
ISO
Amiodarone results in increased expression of FCRL2 mRNA
CTD
PMID:19774075
NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051
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Fdft1
farnesyl diphosphate farnesyl transferase 1
affects expression increases expression
EXP
Amiodarone affects the expression of FDFT1 mRNA Amiodarone results in increased expression of FDFT1 mRNA
CTD
PMID:19483382 PMID:22291062
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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Fdps
farnesyl diphosphate synthase
affects expression increases expression
EXP
Amiodarone affects the expression of FDPS mRNA Amiodarone results in increased expression of FDPS mRNA
CTD
PMID:19483382 PMID:22291062
NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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Fdx2
ferredoxin 2
affects expression
EXP
Amiodarone affects the expression of FDX2 mRNA
CTD
PMID:19483382
NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849
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Ffar3
free fatty acid receptor 3
increases expression
ISO
Amiodarone results in increased expression of FFAR3 mRNA
CTD
PMID:19774075
NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
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Fgd4
FYVE, RhoGEF and PH domain containing 4
increases expression
ISO
Amiodarone results in increased expression of FGD4 mRNA
CTD
PMID:19774075
NCBI chr11:84,399,989...84,551,013
Ensembl chr11:84,399,816...84,546,972
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Fgd5
FYVE, RhoGEF and PH domain containing 5
increases expression
ISO
Amiodarone results in increased expression of FGD5 mRNA
CTD
PMID:19774075
NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563
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Fgf21
fibroblast growth factor 21
increases expression
ISO
Amiodarone results in increased expression of FGF21 mRNA
CTD
PMID:24489787
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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Fgf7
fibroblast growth factor 7
increases expression
EXP
Amiodarone results in increased expression of FGF7 protein
CTD
PMID:32909452
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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Fgfr1op2
FGFR1 oncogene partner 2
increases expression
ISO
Amiodarone results in increased expression of FGFR1OP2 mRNA
CTD
PMID:19774075
NCBI chr 4:179,491,602...179,512,630
Ensembl chr 4:179,491,599...179,512,630
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Fibcd1
fibrinogen C domain containing 1
increases expression
ISO
Amiodarone results in increased expression of FIBCD1 mRNA
CTD
PMID:19774075
NCBI chr 3:15,092,682...15,126,371
Ensembl chr 3:15,092,681...15,126,399
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Fkbp10
FKBP prolyl isomerase 10
increases expression
ISO
Amiodarone results in increased expression of FKBP10 mRNA
CTD
PMID:19774075
NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330
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Fkbp11
FKBP prolyl isomerase 11
decreases expression
ISO
Amiodarone results in decreased expression of FKBP11 mRNA
CTD
PMID:24535564
NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
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Flcn
folliculin
increases expression
ISO
Amiodarone results in increased expression of FLCN mRNA
CTD
PMID:19774075
NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
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Fmo1
flavin containing dimethylaniline monoxygenase 1
affects expression
EXP
Amiodarone affects the expression of FMO1 mRNA
CTD
PMID:19483382
NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
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Fndc4
fibronectin type III domain containing 4
increases expression
ISO
Amiodarone results in increased expression of FNDC4 mRNA
CTD
PMID:17175557 PMID:17567588
NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression multiple interactions
ISO
Amiodarone results in increased expression of FOS mRNA [FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD
PMID:17214612 PMID:19774075 PMID:36586010
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
Amiodarone results in increased expression of FOSB mRNA
CTD
PMID:19774075
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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Foxa1
forkhead box A1
decreases expression
ISO
Amiodarone results in decreased expression of FOXA1 mRNA
CTD
PMID:27089845
NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
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Foxa3
forkhead box A3
decreases expression
EXP ISO
Amiodarone results in decreased expression of FOXA3 mRNA
CTD
PMID:17991464 PMID:24535564
NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
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Foxp3
forkhead box P3
increases expression
ISO
Amiodarone results in increased expression of FOXP3 mRNA
CTD
PMID:19774075
NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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Fras1
Fraser extracellular matrix complex subunit 1
increases expression
ISO
Amiodarone results in increased expression of FRAS1 mRNA
CTD
PMID:19774075
NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726
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Frmd3
FERM domain containing 3
increases expression
ISO
Amiodarone results in increased expression of FRMD3 mRNA
CTD
PMID:19774075
NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091
G
Frmd5
FERM domain containing 5
increases expression
ISO
Amiodarone results in increased expression of FRMD5 mRNA
CTD
PMID:19774075
NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498
G
Ftl1
ferritin light chain 1
increases expression
ISO
Amiodarone results in increased expression of FTL mRNA
CTD
PMID:36586010
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
Fundc2
FUN14 domain containing 2
increases expression
ISO
Amiodarone results in increased expression of FUNDC2 mRNA
CTD
PMID:19774075
NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
G
Fut4
fucosyltransferase 4
decreases expression
EXP
Amiodarone results in decreased expression of FUT4 mRNA
CTD
PMID:17991464
NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
G
Fuz
fuzzy planar cell polarity protein
increases expression
ISO
Amiodarone results in increased expression of FUZ mRNA
CTD
PMID:19774075
NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
G
Fxyd1
FXYD domain-containing ion transport regulator 1
increases expression
ISO
Amiodarone results in increased expression of FXYD1 mRNA
CTD
PMID:19774075
NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
G
G6pd
glucose-6-phosphate dehydrogenase
increases expression
EXP ISO
Amiodarone results in increased expression of G6PDX mRNA Amiodarone results in increased expression of G6PD mRNA
CTD
PMID:19224547 PMID:19774075
NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
Amiodarone results in increased expression of GADD45A mRNA
CTD
PMID:19774075
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gadd45g
growth arrest and DNA-damage-inducible, gamma
increases expression
ISO
Amiodarone results in increased expression of GADD45G mRNA
CTD
PMID:19774075
NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
G
Gal
galanin and GMAP prepropeptide
increases expression
EXP
Amiodarone results in increased expression of GAL mRNA
CTD
PMID:25580480
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
G
Gal3st3
galactose-3-O-sulfotransferase 3
increases expression
ISO
Amiodarone results in increased expression of GAL3ST3 mRNA
CTD
PMID:19774075
NCBI chr 1:202,593,635...202,603,446
Ensembl chr 1:202,593,692...202,603,445
G
Galnt17
polypeptide N-acetylgalactosaminyltransferase 17
increases expression
ISO
Amiodarone results in increased expression of GALNT17 mRNA
CTD
PMID:19774075
NCBI chr12:25,323,230...25,781,897
Ensembl chr12:25,322,701...25,781,290
G
Gamt
guanidinoacetate N-methyltransferase
affects expression
EXP
Amiodarone affects the expression of GAMT mRNA
CTD
PMID:19483382
NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778
G
Gapdh
glyceraldehyde-3-phosphate dehydrogenase
affects expression
EXP
Amiodarone affects the expression of GAPDH mRNA
CTD
PMID:19483382
NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
G
Gata2
GATA binding protein 2
decreases expression
EXP
Amiodarone results in decreased expression of GATA2 mRNA
CTD
PMID:17991464
NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
G
Gatb
glutamyl-tRNA amidotransferase subunit B
increases expression
ISO
Amiodarone results in increased expression of GATB mRNA
CTD
PMID:24535564
NCBI chr 2:170,930,547...171,017,133
Ensembl chr 2:170,930,542...171,016,695
G
Gbe1
1,4-alpha-glucan branching enzyme 1
affects expression
EXP
Amiodarone affects the expression of GBE1 mRNA
CTD
PMID:19483382
NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
G
Gbp2
guanylate binding protein 2
increases expression
ISO
Amiodarone results in increased expression of GBP2 mRNA
CTD
PMID:19774075
NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
G
Gchfr
GTP cyclohydrolase I feedback regulator
affects expression
EXP
Amiodarone affects the expression of GCHFR mRNA
CTD
PMID:19483382
NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
G
Gckr
glucokinase regulator
affects expression
EXP
Amiodarone affects the expression of GCKR mRNA
CTD
PMID:18355885
NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
G
Gclm
glutamate cysteine ligase, modifier subunit
increases expression
ISO
Amiodarone results in increased expression of GCLM mRNA
CTD
PMID:36586010
NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
G
Gdf15
growth differentiation factor 15
increases expression
ISO
Amiodarone results in increased expression of GDF15 mRNA
CTD
PMID:19774075 PMID:36586010
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gdf5
growth differentiation factor 5
increases expression
ISO
Amiodarone results in increased expression of GDF5 mRNA
CTD
PMID:19774075
NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612
G
Gdpd3
glycerophosphodiester phosphodiesterase domain containing 3
increases expression
ISO
Amiodarone results in increased expression of GDPD3 mRNA
CTD
PMID:17175557 PMID:17567588
NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063
G
Gem
GTP binding protein overexpressed in skeletal muscle
increases expression
ISO
Amiodarone results in increased expression of GEM mRNA
CTD
PMID:19774075
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
G
Gfap
glial fibrillary acidic protein
increases expression
EXP
Amiodarone results in increased expression of GFAP mRNA
CTD
PMID:22954530 PMID:25659768
NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
G
Gfod1
Gfo/Idh/MocA-like oxidoreductase domain containing 1
increases expression
ISO
Amiodarone results in increased expression of GFOD1 mRNA
CTD
PMID:19774075
NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938
G
Ggh
gamma-glutamyl hydrolase
affects expression
EXP
Amiodarone affects the expression of GGH mRNA
CTD
PMID:19483382
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
G
Gh1
growth hormone 1
multiple interactions
EXP
Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA]
CTD
PMID:2910914
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
G
Gins1
GINS complex subunit 1
increases expression
ISO
Amiodarone results in increased expression of GINS1 mRNA
CTD
PMID:19774075
NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
G
Gja1
gap junction protein, alpha 1
decreases expression
ISO
Amiodarone results in decreased expression of GJA1 mRNA
CTD
PMID:15520326
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Gja5
gap junction protein, alpha 5
increases expression
ISO
Amiodarone results in increased expression of GJA5 mRNA
CTD
PMID:19774075
NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
G
Gjb1
gap junction protein, beta 1
affects expression
EXP
Amiodarone affects the expression of GJB1 mRNA
CTD
PMID:19483382
NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925
G
Gjd3
gap junction protein, delta 3
increases expression
ISO
Amiodarone results in increased expression of GJD3 mRNA
CTD
PMID:19774075
NCBI chr10:83,933,694...83,935,759
Ensembl chr10:83,934,135...83,934,971
G
Gk5
glycerol kinase 5
increases expression
ISO
Amiodarone results in increased expression of GK5 mRNA
CTD
PMID:19774075
NCBI chr 8:96,682,469...96,751,407
Ensembl chr 8:96,682,470...96,749,166
G
Gkap1
G kinase anchoring protein 1
increases expression
ISO
Amiodarone results in increased expression of GKAP1 mRNA
CTD
PMID:19774075
NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679
G
Gls2
glutaminase 2
affects expression
EXP
Amiodarone affects the expression of GLS2 mRNA
CTD
PMID:18355885
NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
G
Glud1
glutamate dehydrogenase 1
increases expression
EXP
Amiodarone results in increased expression of GLUD1 protein
CTD
PMID:16538043
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
G
Gnas
GNAS complex locus
increases expression
ISO
Amiodarone results in increased expression of GNAS mRNA
CTD
PMID:19774075
NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262 Ensembl chr 3:163,071,417...163,127,262
G
Gnl1
G protein nucleolar 1
decreases expression
EXP
Amiodarone results in decreased expression of GNL1 mRNA
CTD
PMID:17991464
NCBI chr20:2,783,130...2,792,115
Ensembl chr20:2,778,985...2,792,115
G
Gnpat
glyceronephosphate O-acyltransferase
increases expression
EXP
Amiodarone results in increased expression of GNPAT mRNA
CTD
PMID:22291062
NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361
G
Gon4l
gon-4 like
increases expression
ISO
Amiodarone results in increased expression of GON4L mRNA
CTD
PMID:19774075
NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
G
Got2
glutamic-oxaloacetic transaminase 2
affects expression
EXP
Amiodarone affects the expression of GOT2 mRNA
CTD
PMID:18355885
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
G
Gpam
glycerol-3-phosphate acyltransferase, mitochondrial
increases expression
EXP
Amiodarone results in increased expression of GPAM mRNA
CTD
PMID:19224547
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
G
Gpat3
glycerol-3-phosphate acyltransferase 3
increases expression
ISO
Amiodarone results in increased expression of GPAT3 mRNA
CTD
PMID:24535564
NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
G
Gpld1
glycosylphosphatidylinositol specific phospholipase D1
affects expression
EXP
Amiodarone affects the expression of GPLD1 mRNA
CTD
PMID:19483382
NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
G
Gprc5c
G protein-coupled receptor, class C, group 5, member C
increases expression
ISO
Amiodarone results in increased expression of GPRC5C mRNA
CTD
PMID:19774075
NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
G
Gpt
glutamic--pyruvic transaminase
increases expression multiple interactions increases activity
ISO EXP
Amiodarone results in increased expression of GPT protein 1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [Dexamethasone results in increased susceptibility to Amiodarone] which results in increased expression of GPT protein; Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]; gadolinium chloride inhibits the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]] Amiodarone results in increased activity of GPT protein
CTD
PMID:8522712 PMID:22291062 PMID:24685772 PMID:25900201 PMID:32084307 PMID:34259586 More...
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpt2
glutamic--pyruvic transaminase 2
increases expression
ISO
Amiodarone results in increased expression of GPT2 mRNA
CTD
PMID:24489787
NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
G
Gpx1
glutathione peroxidase 1
affects expression multiple interactions decreases expression
EXP ISO
Amiodarone affects the expression of GPX1 mRNA ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]
CTD
PMID:19483382 PMID:34434487
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
G
Gpx4
glutathione peroxidase 4
affects expression
EXP
Amiodarone affects the expression of GPX4 mRNA
CTD
PMID:19483382
NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
G
Grb14
growth factor receptor bound protein 14
affects expression
EXP
Amiodarone affects the expression of GRB14 mRNA
CTD
PMID:18355885
NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
G
Grina
glutamate ionotropic receptor NMDA type subunit associated protein 1
affects expression
EXP
Amiodarone affects the expression of GRINA mRNA
CTD
PMID:19483382
NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
G
Grm2
glutamate metabotropic receptor 2
increases expression
ISO
Amiodarone results in increased expression of GRM2 mRNA
CTD
PMID:19774075
NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
G
Grpel1
GrpE-like 1, mitochondrial
affects expression
EXP
Amiodarone affects the expression of GRPEL1 mRNA
CTD
PMID:19483382
NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
G
Gsk3b
glycogen synthase kinase 3 beta
decreases phosphorylation
ISO
Amiodarone results in decreased phosphorylation of GSK3B protein
CTD
PMID:26515726
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsn
gelsolin
increases expression
EXP
Amiodarone results in increased expression of GSN mRNA
CTD
PMID:17991464
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gsta2
glutathione S-transferase alpha 2
increases expression
ISO
Amiodarone results in increased expression of GSTA2 mRNA
CTD
PMID:36586010
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gsto2
glutathione S-transferase omega 2
increases expression
ISO
Amiodarone results in increased expression of GSTO2 mRNA
CTD
PMID:19774075
NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
G
Gstt1
glutathione S-transferase theta 1
affects expression
EXP
Amiodarone affects the expression of GSTT1 mRNA
CTD
PMID:19483382
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gstz1
glutathione S-transferase zeta 1
increases expression
ISO
Amiodarone results in increased expression of GSTZ1 mRNA
CTD
PMID:19774075
NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
G
Gtf2h5
general transcription factor IIH subunit 5
affects expression
EXP
Amiodarone affects the expression of GTF2H5 mRNA
CTD
PMID:19483382
NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
G
Gucy1a2
guanylate cyclase 1 soluble subunit alpha 2
increases expression
ISO
Amiodarone results in increased expression of GUCY1A2 mRNA
CTD
PMID:19774075
NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203
G
Gucy1b1
guanylate cyclase 1 soluble subunit beta 1
increases expression
ISO
Amiodarone results in increased expression of GUCY1B1 mRNA
CTD
PMID:19774075
NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
G
Gzma
granzyme A
affects expression
EXP
Amiodarone affects the expression of GZMA mRNA
CTD
PMID:19483382
NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
G
H2aj
H2A.J histone
increases expression
ISO
Amiodarone results in increased expression of H2AJ mRNA
CTD
PMID:19774075
NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006
G
H2bc6
H2B clustered histone 6
increases expression
ISO
Amiodarone results in increased expression of H2BC6 mRNA
CTD
PMID:19774075
NCBI chr17:41,520,775...41,521,238
G
H3f3b
H3.3 histone B
affects expression
EXP
Amiodarone affects the expression of H3F3B mRNA
CTD
PMID:19483382
NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709
G
Hal
histidine ammonia lyase
affects expression
EXP
Amiodarone affects the expression of HAL mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
G
Hao2
hydroxyacid oxidase 2
affects expression
EXP
Amiodarone affects the expression of HAO2 mRNA
CTD
PMID:19483382
NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
G
Hba-a2
hemoglobin alpha, adult chain 2
affects expression
EXP
Amiodarone affects the expression of HBA-A2 mRNA
CTD
PMID:19483382
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
G
Hbb
hemoglobin subunit beta
affects expression
EXP
Amiodarone affects the expression of HBB mRNA
CTD
PMID:19483382
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
G
Hcn1
hyperpolarization-activated cyclic nucleotide-gated potassium channel 1
increases expression
ISO
Amiodarone results in increased expression of HCN1 mRNA
CTD
PMID:19774075
NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774
G
Hcn2
hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
decreases expression
EXP
Amiodarone results in decreased expression of HCN2 mRNA
CTD
PMID:17711693
NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841
G
Hcn4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
decreases expression
EXP
Amiodarone results in decreased expression of HCN4 mRNA
CTD
PMID:17711693
NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639
G
Hdc
histidine decarboxylase
affects expression
EXP
Amiodarone affects the expression of HDC mRNA
CTD
PMID:19483382
NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
G
Hdx
highly divergent homeobox
increases expression
ISO
Amiodarone results in increased expression of HDX mRNA
CTD
PMID:19774075
NCBI chr X:76,552,539...76,697,177
Ensembl chr X:76,560,665...76,869,972
G
Helb
DNA helicase B
increases expression
ISO
Amiodarone results in increased expression of HELB mRNA
CTD
PMID:19774075
NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
G
Herpud1
homocysteine inducible ER protein with ubiquitin like domain 1
increases expression
ISO
Amiodarone results in increased expression of HERPUD1 mRNA
CTD
PMID:19774075 PMID:36586010
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
G
Hes6
hes family bHLH transcription factor 6
decreases expression
EXP
Amiodarone results in decreased expression of HES6 mRNA
CTD
PMID:17991464
NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
G
Hexa
hexosaminidase subunit alpha
increases expression multiple interactions
ISO
Amiodarone results in increased expression of HEXA mRNA Amiodarone results in increased activity of and results in increased secretion of HEXA protein
CTD
PMID:25881747
NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
G
Hexb
hexosaminidase subunit beta
multiple interactions
ISO
Amiodarone results in increased activity of and results in increased secretion of HEXB protein
CTD
PMID:25881747
NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
G
Hexim1
HEXIM P-TEFb complex subunit 1
increases expression
ISO
Amiodarone results in increased expression of HEXIM1 mRNA
CTD
PMID:19774075
NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189
G
Hgd
homogentisate 1, 2-dioxygenase
affects expression
EXP
Amiodarone affects the expression of HGD mRNA
CTD
PMID:19483382
NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
G
Hgfac
HGF activator
increases expression
ISO
Amiodarone results in increased expression of HGFAC mRNA
CTD
PMID:19774075
NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278
G
Hif1a
hypoxia inducible factor 1 subunit alpha
decreases expression
ISO
Amiodarone results in decreased expression of HIF1A mRNA
CTD
PMID:35641671
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hira
histone cell cycle regulator
increases expression
ISO
Amiodarone results in increased expression of HIRA mRNA
CTD
PMID:19774075
NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529
G
Hjv
hemojuvelin BMP co-receptor
increases expression
ISO
Amiodarone results in increased expression of HJV mRNA
CTD
PMID:24535564
NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850
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Hmgb2
high mobility group box 2
affects expression
EXP
Amiodarone affects the expression of HMGB2 mRNA
CTD
PMID:18355885
NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
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Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression
ISO
Amiodarone results in increased expression of HMGCR mRNA
CTD
PMID:24489787
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
EXP
Amiodarone results in increased expression of HMGCS1 mRNA
CTD
PMID:22291062
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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Hmgn1
high mobility group nucleosome binding domain 1
affects expression
EXP
Amiodarone affects the expression of HMGN1 mRNA
CTD
PMID:19483382
NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
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Hmgxb4
HMG-box containing 4
increases expression
ISO
Amiodarone results in increased expression of HMGXB4 mRNA
CTD
PMID:19774075
NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563
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Hmox1
heme oxygenase 1
increases expression affects expression
ISO EXP
Amiodarone results in increased expression of HMOX1 mRNA Amiodarone affects the expression of HMOX1 mRNA
CTD
PMID:18020914 PMID:19224547 PMID:19774075 PMID:25659768 PMID:31324950 PMID:36586010 More...
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnf4a
hepatocyte nuclear factor 4, alpha
increases expression
ISO
Amiodarone results in increased expression of HNF4A mRNA
CTD
PMID:24489787
NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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Hnf4g
hepatocyte nuclear factor 4, gamma
increases expression
ISO
Amiodarone results in increased expression of HNF4G mRNA
CTD
PMID:19774075
NCBI chr 2:97,885,773...98,036,650
Ensembl chr 2:97,887,432...98,036,592
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Hnrnpa1
heterogeneous nuclear ribonucleoprotein A1
increases expression
ISO
Amiodarone results in increased expression of HNRNPA1 mRNA
CTD
PMID:21163907
NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
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Hoxb6
homeo box B6
increases expression
ISO
Amiodarone results in increased expression of HOXB6 mRNA
CTD
PMID:19774075
NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449
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Hoxc4
homeo box C4
increases expression
ISO
Amiodarone results in increased expression of HOXC4 mRNA
CTD
PMID:19774075
NCBI chr 7:134,135,279...134,173,133
Ensembl chr 7:134,170,591...134,173,133
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Hpn
hepsin
increases expression
ISO
Amiodarone results in increased expression of HPN mRNA
CTD
PMID:15342952 PMID:17567588
NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
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Hprt1
hypoxanthine phosphoribosyltransferase 1
affects expression
EXP
Amiodarone affects the expression of HPRT1 mRNA
CTD
PMID:19483382
NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
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Hps5
HPS5, biogenesis of lysosomal organelles complex 2 subunit 2
affects expression
EXP
Amiodarone affects the expression of HPS5 mRNA
CTD
PMID:19483382
NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
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Hrk
harakiri, BCL2 interacting protein
increases expression
ISO
Amiodarone results in increased expression of HRK mRNA
CTD
PMID:19774075
NCBI chr12:38,387,484...38,409,652
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Hscb
HscB mitochondrial iron-sulfur cluster co-chaperone
increases expression
ISO
Amiodarone results in increased expression of HSCB mRNA
CTD
PMID:24535564
NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909
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Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
increases expression
ISO
Amiodarone results in increased expression of HSD17B11 mRNA
CTD
PMID:24535564
NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
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Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4
affects expression
EXP
Amiodarone affects the expression of HSD17B4 mRNA
CTD
PMID:19483382
NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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Hsdl2
hydroxysteroid dehydrogenase like 2
affects expression
EXP
Amiodarone affects the expression of HSDL2 mRNA
CTD
PMID:19483382
NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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Hspa5
heat shock protein family A (Hsp70) member 5
increases expression multiple interactions
ISO
Amiodarone results in increased expression of HSPA5 mRNA; Amiodarone results in increased expression of HSPA5 protein 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA] 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 protein]
CTD
PMID:25295624 PMID:34259586 PMID:36586010
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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Hspd1
heat shock protein family D (Hsp60) member 1
increases expression
EXP
Amiodarone results in increased expression of HSPD1 protein
CTD
PMID:16538043
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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Htatip2
HIV-1 Tat interactive protein 2
increases expression
ISO
Amiodarone results in increased expression of HTATIP2 mRNA
CTD
PMID:24535564
NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
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Htra1
HtrA serine peptidase 1
affects expression
EXP
Amiodarone affects the expression of HTRA1 mRNA
CTD
PMID:19483382
NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
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Htra2
HtrA serine peptidase 2
increases expression
ISO
Amiodarone results in increased expression of HTRA2 mRNA
CTD
PMID:24489787
NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
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Hus1
HUS1 checkpoint clamp component
increases expression
ISO
Amiodarone results in increased expression of HUS1 mRNA
CTD
PMID:19774075
NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
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Icam1
intercellular adhesion molecule 1
increases expression multiple interactions
ISO
Amiodarone results in increased expression of ICAM1 mRNA [Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein
CTD
PMID:19774075 PMID:22785256
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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Id2
inhibitor of DNA binding 2
increases expression
ISO
Amiodarone results in increased expression of ID2 mRNA
CTD
PMID:23397585
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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Idh2
isocitrate dehydrogenase (NADP(+)) 2
increases expression
ISO
Amiodarone results in increased expression of IDH2 mRNA
CTD
PMID:24489787
NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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Ifng
interferon gamma
multiple interactions decreases expression
EXP ISO
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Losartan inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Prednisolone inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Vitamin D inhibits the reaction [Amiodarone results in decreased expression of IFNG protein] Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]
CTD
PMID:25073960 PMID:34590760
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Igf1
insulin-like growth factor 1
affects expression
EXP
Amiodarone affects the expression of IGF1 mRNA
CTD
PMID:19483382
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Igfals
insulin-like growth factor binding protein, acid labile subunit
increases expression affects expression
ISO EXP
Amiodarone results in increased expression of IGFALS mRNA Amiodarone affects the expression of IGFALS mRNA
CTD
PMID:19483382 PMID:19774075
NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
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Igfbp1
insulin-like growth factor binding protein 1
increases expression
ISO
Amiodarone results in increased expression of IGFBP1 mRNA
CTD
PMID:27089845
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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Igfbp2
insulin-like growth factor binding protein 2
affects expression
EXP
Amiodarone affects the expression of IGFBP2 mRNA
CTD
PMID:19483382
NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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Igsf8
immunoglobulin superfamily, member 8
increases expression
ISO
Amiodarone results in increased expression of IGSF8 mRNA
CTD
PMID:19774075
NCBI chr13:84,770,348...84,781,534
Ensembl chr13:84,770,279...84,778,576
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Il10
interleukin 10
decreases expression multiple interactions
ISO
Amiodarone results in decreased expression of IL10 mRNA; Amiodarone results in decreased expression of IL10 protein ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]
CTD
PMID:34434487
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il10ra
interleukin 10 receptor subunit alpha
increases expression
ISO
Amiodarone results in increased expression of IL10RA mRNA
CTD
PMID:19774075
NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
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Il18
interleukin 18
multiple interactions
ISO
Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA]
CTD
PMID:25900201
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
increases expression multiple interactions
ISO
Amiodarone results in increased expression of IL1A mRNA [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone
CTD
PMID:19362101 PMID:19774075
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
multiple interactions increases expression
ISO EXP
[Amiodarone co-treated with Dexamethasone] results in decreased expression of IL1B mRNA Amiodarone results in increased expression of IL1B mRNA; Amiodarone results in increased expression of IL1B protein ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]
CTD
PMID:25580480 PMID:25900201 PMID:34434487
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il2
interleukin 2
multiple interactions
ISO
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein]
CTD
PMID:25073960
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il33
interleukin 33
affects expression
EXP
Amiodarone affects the expression of IL33 mRNA
CTD
PMID:18355885
NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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Il4
interleukin 4
multiple interactions
EXP ISO
[Vitamin D co-treated with Losartan] inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL4 protein] Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]
CTD
PMID:25073960 PMID:34590760
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6
interleukin 6
increases expression multiple interactions increases secretion
ISO EXP
Amiodarone results in increased expression of IL6 mRNA; Amiodarone results in increased expression of IL6 protein [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL6 protein] [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; Prednisolone inhibits the reaction [Amiodarone results in increased secretion of IL6 protein]
CTD
PMID:11288978 PMID:19362101 PMID:34434487 PMID:34590760
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Impa1
inositol monophosphatase 1
affects expression
EXP
Amiodarone affects the expression of IMPA1 mRNA
CTD
PMID:19483382
NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
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Inhba
inhibin subunit beta A
decreases expression
ISO
Amiodarone results in decreased expression of INHBA mRNA
CTD
PMID:24535564
NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
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Inhbe
inhibin subunit beta E
affects expression increases expression
EXP ISO
Amiodarone affects the expression of INHBE mRNA Amiodarone results in increased expression of INHBE mRNA
CTD
PMID:15342952 PMID:17175557 PMID:17567588 PMID:19483382 PMID:19774075
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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Inka2
inka box actin regulator 2
increases expression
ISO
Amiodarone results in increased expression of INKA2 mRNA
CTD
PMID:19774075
NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:193,185,275...193,200,642
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Ins2
insulin 2
multiple interactions
ISO
INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein]
CTD
PMID:28962527
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Ippk
inositol-pentakisphosphate 2-kinase
increases expression
ISO
Amiodarone results in increased expression of IPPK mRNA
CTD
PMID:19774075
NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541
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Irak2
interleukin-1 receptor-associated kinase 2
increases expression
ISO
Amiodarone results in increased expression of IRAK2 mRNA
CTD
PMID:19774075
NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
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Irf1
interferon regulatory factor 1
increases expression
ISO
Amiodarone results in increased expression of IRF1 mRNA
CTD
PMID:19774075
NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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Isx
intestine-specific homeobox
increases expression
ISO
Amiodarone results in increased expression of ISX mRNA
CTD
PMID:19774075
NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760
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Isyna1
inositol-3-phosphate synthase 1
affects expression
EXP
Amiodarone affects the expression of ISYNA1 mRNA
CTD
PMID:19483382
NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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Itgb5
integrin subunit beta 5
decreases expression
ISO
Amiodarone results in decreased expression of ITGB5 mRNA
CTD
PMID:23397585
NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
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Itih2
inter-alpha-trypsin inhibitor heavy chain 2
increases expression
ISO
Amiodarone results in increased expression of ITIH2 mRNA
CTD
PMID:19774075
NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841
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Itih4
inter-alpha-trypsin inhibitor heavy chain 4
affects expression
EXP
Amiodarone affects the expression of ITIH4 mRNA
CTD
PMID:19483382
NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
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Ivns1abp
influenza virus NS1A binding protein
increases expression
EXP
Amiodarone results in increased expression of IVNS1ABP mRNA
CTD
PMID:17991464
NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
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Jak1
Janus kinase 1
affects expression
EXP
Amiodarone affects the expression of JAK1 mRNA
CTD
PMID:19483382
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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Jakmip3
janus kinase and microtubule interacting protein 3
increases expression
ISO
Amiodarone results in increased expression of JAKMIP3 mRNA
CTD
PMID:19774075
NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104
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Jrkl
JRK-like
increases expression
ISO
Amiodarone results in increased expression of JRKL mRNA
CTD
PMID:19774075
NCBI chr 8:10,224,172...10,227,068
Ensembl chr 8:10,224,172...10,227,068
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Jun
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression multiple interactions increases phosphorylation
EXP ISO
Amiodarone results in increased expression of JUN mRNA; Amiodarone results in increased expression of JUN protein [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein] [FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]
CTD
PMID:11597910 PMID:17214612 PMID:25073960 PMID:34590760
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Kcna4
potassium voltage-gated channel subfamily A member 4
increases expression
ISO
Amiodarone results in increased expression of KCNA4 mRNA
CTD
PMID:15520326
NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162
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Kcna5
potassium voltage-gated channel subfamily A member 5
decreases expression
ISO EXP
Amiodarone results in decreased expression of KCNA5 mRNA
CTD
PMID:8973384 PMID:9302343 PMID:15520326
NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
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Kcnab1
potassium voltage-gated channel subfamily A regulatory beta subunit 1
increases expression
ISO
Amiodarone results in increased expression of KCNAB1 mRNA
CTD
PMID:15520326
NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
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Kcnb1
potassium voltage-gated channel subfamily B member 1
decreases expression
ISO
Amiodarone results in decreased expression of KCNB1 mRNA
CTD
PMID:15520326
NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
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Kcnd2
potassium voltage-gated channel subfamily D member 2
decreases expression
ISO
Amiodarone results in decreased expression of KCND2 mRNA
CTD
PMID:15520326
NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
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Kcne3
potassium voltage-gated channel subfamily E regulatory subunit 3
increases expression
ISO
Amiodarone results in increased expression of KCNE3 mRNA
CTD
PMID:15520326
NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
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Kcne5
potassium voltage-gated channel subfamily E regulatory subunit 5
increases expression
ISO
Amiodarone results in increased expression of KCNE5 mRNA
CTD
PMID:19774075
NCBI chr X:105,930,398...105,931,013
Ensembl chr X:105,930,398...105,931,013
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Kcnh2
potassium voltage-gated channel subfamily H member 2
affects activity increases expression decreases activity multiple interactions
ISO EXP
Amiodarone affects the activity of KCNH2 protein Amiodarone results in increased expression of KCNH2 mRNA Amiodarone results in decreased activity of KCNH2 protein Amiodarone binds to and results in decreased activity of KCNH2 protein; Amiodarone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; Amiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]; Potassium inhibits the reaction [Amiodarone results in decreased activity of KCNH2 protein]
CTD
PMID:10208308 PMID:11238279 PMID:15272206 PMID:15618689 PMID:15671647 PMID:15821840 PMID:16960444 PMID:16971508 PMID:18057881 PMID:18724381 PMID:19583963 PMID:21158687 PMID:22020101 PMID:22291062 PMID:24052561 More...
NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Kcnj2
potassium inwardly-rectifying channel, subfamily J, member 2
increases expression
ISO
Amiodarone results in increased expression of KCNJ2 mRNA
CTD
PMID:19774075
NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
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Kcnk1
potassium two pore domain channel subfamily K member 1
increases expression
ISO
Amiodarone results in increased expression of KCNK1 mRNA
CTD
PMID:15520326
NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
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Kcnk12
potassium two pore domain channel subfamily K member 12
increases expression
ISO
Amiodarone results in increased expression of KCNK12 mRNA
CTD
PMID:19774075
NCBI chr 6:6,740,147...6,790,664
Ensembl chr 6:6,739,991...6,790,661
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Kcnma1
potassium calcium-activated channel subfamily M alpha 1
increases expression
ISO
Amiodarone results in increased expression of KCNMA1 mRNA
CTD
PMID:19774075
NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198
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Kctd14
potassium channel tetramerization domain containing 14
increases expression
ISO
Amiodarone results in increased expression of KCTD14 mRNA
CTD
PMID:19774075
NCBI chr 1:151,761,688...151,766,693
Ensembl chr 1:151,761,663...151,766,691
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Kdelr2
KDEL endoplasmic reticulum protein retention receptor 2
affects expression
EXP
Amiodarone affects the expression of KDELR2 mRNA
CTD
PMID:19483382
NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
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Kdr
kinase insert domain receptor
affects expression
EXP
Amiodarone affects the expression of KDR mRNA
CTD
PMID:19483382
NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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Keap1
Kelch-like ECH-associated protein 1
decreases expression
EXP
Amiodarone results in decreased expression of KEAP1 mRNA
CTD
PMID:17991464
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Khdrbs3
KH RNA binding domain containing, signal transduction associated 3
increases expression
ISO
Amiodarone results in increased expression of KHDRBS3 mRNA
CTD
PMID:24535564
NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
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Kif16b
kinesin family member 16B
increases expression
ISO
Amiodarone results in increased expression of KIF16B mRNA
CTD
PMID:19774075
NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
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Kif17
kinesin family member 17
increases expression
ISO
Amiodarone results in increased expression of KIF17 mRNA
CTD
PMID:19774075
NCBI chr 5:150,482,288...150,521,471
Ensembl chr 5:150,481,578...150,519,638
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Kifc1
kinesin family member C1
increases expression
ISO
Amiodarone results in increased expression of KIFC1 mRNA
CTD
PMID:19774075
NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
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Kitlg
KIT ligand
increases expression
ISO
Amiodarone results in increased expression of KITLG mRNA
CTD
PMID:19774075
NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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Klf10
KLF transcription factor 10
increases expression
ISO
Amiodarone results in increased expression of KLF10 mRNA
CTD
PMID:19774075
NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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Klf15
KLF transcription factor 15
increases expression
ISO
Amiodarone results in increased expression of KLF15 mRNA
CTD
PMID:19774075
NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
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Klf16
KLF transcription factor 16
increases expression
ISO
Amiodarone results in increased expression of KLF16 mRNA
CTD
PMID:19774075
NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317
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Klf4
KLF transcription factor 4
increases expression
ISO
Amiodarone results in increased expression of KLF4 mRNA
CTD
PMID:19774075
NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
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Klhl28
kelch-like family member 28
increases expression
ISO
Amiodarone results in increased expression of KLHL28 mRNA
CTD
PMID:19774075
NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164
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Klk14
kallikrein related-peptidase 14
increases expression
ISO
Amiodarone results in increased expression of KLK14 mRNA
CTD
PMID:19774075
NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240
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Krt17
keratin 17
increases expression
ISO
Amiodarone results in increased expression of KRT17 mRNA
CTD
PMID:19774075
NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
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Krt23
keratin 23
increases expression
ISO
Amiodarone results in increased expression of KRT23 mRNA
CTD
PMID:24535564
NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983
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Krt8
keratin 8
affects expression
EXP
Amiodarone affects the expression of KRT8 mRNA
CTD
PMID:19483382
NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
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L3mbtl1
L3MBTL histone methyl-lysine binding protein 1
increases expression
ISO
Amiodarone results in increased expression of L3MBTL1 mRNA
CTD
PMID:19774075
NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
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Lama2
laminin subunit alpha 2
increases expression
ISO
Amiodarone results in increased expression of LAMA2 mRNA
CTD
PMID:24489787
NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530
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Lars2
leucyl-tRNA synthetase 2, mitochondrial
increases expression
ISO
Amiodarone results in increased expression of LARS2 mRNA
CTD
PMID:24489787
NCBI chr 8:123,010,271...123,106,395
Ensembl chr 8:123,010,293...123,106,395
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Lcat
lecithin cholesterol acyltransferase
affects expression increases expression
EXP
Amiodarone affects the expression of LCAT mRNA Amiodarone results in increased expression of LCAT mRNA
CTD
PMID:19483382 PMID:22291062
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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Lcmt1
leucine carboxyl methyltransferase 1
affects expression
EXP
Amiodarone affects the expression of LCMT1 mRNA
CTD
PMID:19483382
NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
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Lctl
lactase-like
increases expression
ISO
Amiodarone results in increased expression of LCTL mRNA
CTD
PMID:19774075
NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357
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Ldlr
low density lipoprotein receptor
multiple interactions decreases expression
ISO EXP
Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA] Amiodarone results in decreased expression of LDLR mRNA; Amiodarone results in decreased expression of LDLR protein Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein]
CTD
PMID:8137927 PMID:9071962 PMID:9712728 PMID:9751232 PMID:12538616
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lhcgr
luteinizing hormone/choriogonadotropin receptor
increases expression
ISO
Amiodarone results in increased expression of LHCGR mRNA
CTD
PMID:19774075
NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
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Lif
LIF, interleukin 6 family cytokine
increases expression
ISO
Amiodarone results in increased expression of LIF mRNA
CTD
PMID:19774075
NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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Lin7a
lin-7 homolog A, crumbs cell polarity complex component
increases expression
ISO
Amiodarone results in increased expression of LIN7A mRNA
CTD
PMID:19774075
NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
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Lipc
lipase C, hepatic type
affects expression
EXP
Amiodarone affects the expression of LIPC mRNA
CTD
PMID:19483382
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipe
lipase E, hormone sensitive type
multiple interactions increases phosphorylation
ISO
INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein]
CTD
PMID:28962527 PMID:34259586
NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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LOC103689958
olfactory receptor 49-like
increases expression
ISO
Amiodarone results in increased expression of OR6T1 mRNA
CTD
PMID:19774075
NCBI chr 1:65,911,907...65,913,255
Ensembl chr 1:65,912,105...65,913,079
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Lox
lysyl oxidase
affects expression
EXP
Amiodarone affects the expression of LOX mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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Lpcat3
lysophosphatidylcholine acyltransferase 3
increases expression
ISO
Amiodarone results in increased expression of LPCAT3 mRNA
CTD
PMID:24489787
NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
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Lpgat1
lysophosphatidylglycerol acyltransferase 1
increases expression
EXP
Amiodarone results in increased expression of LPGAT1 mRNA
CTD
PMID:22291062
NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
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Lpin3
lipin 3
increases expression
ISO
Amiodarone results in increased expression of LPIN3 mRNA
CTD
PMID:24489787
NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
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Lrp3
LDL receptor related protein 3
affects expression
EXP
Amiodarone affects the expression of LRP3 mRNA
CTD
PMID:19483382
NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
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Lrp5
LDL receptor related protein 5
increases expression
ISO
Amiodarone results in increased expression of LRP5 mRNA
CTD
PMID:19774075
NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
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Lss
lanosterol synthase
increases expression affects expression
EXP ISO
Amiodarone results in increased expression of LSS mRNA Amiodarone affects the expression of LSS mRNA
CTD
PMID:15342952 PMID:17567588 PMID:19224547 PMID:22291062 PMID:24489787 PMID:29248575 More...
NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
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Ly6d
lymphocyte antigen 6 family member D
increases expression
ISO
Amiodarone results in increased expression of LY6D mRNA
CTD
PMID:24489787
NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
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Lyz2
lysozyme 2
increases expression
ISO
Amiodarone results in increased expression of LYZ mRNA
CTD
PMID:19774075
NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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Macrod2
mono-ADP ribosylhydrolase 2
increases expression
ISO
Amiodarone results in increased expression of MACROD2 mRNA
CTD
PMID:19774075
NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492
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Macroh2a1
macroH2A.1 histone
affects expression
EXP
Amiodarone affects the expression of MACROH2A1 mRNA
CTD
PMID:18355885
NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
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Maff
MAF bZIP transcription factor F
increases expression
ISO
Amiodarone results in increased expression of MAFF mRNA
CTD
PMID:36586010
NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
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Mafg
MAF bZIP transcription factor G
increases expression
ISO
Amiodarone results in increased expression of MAFG mRNA
CTD
PMID:19774075 PMID:36586010
NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
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Man2b1
mannosidase, alpha, class 2B, member 1
affects expression
EXP
Amiodarone affects the expression of MAN2B1 mRNA
CTD
PMID:19483382
NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
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Manba
mannosidase beta
affects expression
EXP
Amiodarone affects the expression of MANBA mRNA
CTD
PMID:18355885
NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983
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Map1lc3b
microtubule-associated protein 1 light chain 3 beta
increases lipidation multiple interactions
ISO
Amiodarone results in increased lipidation of MAP1LC3B protein Amiodarone results in increased expression of and results in increased lipidation of MAP1LC3B protein; Amiodarone results in increased lipidation of and results in increased localization of MAP1LC3B protein
CTD
PMID:25881747 PMID:32651653 PMID:37661063
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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Map2k1
mitogen activated protein kinase kinase 1
multiple interactions
ISO
MAP2K1 protein inhibits the reaction [Amiodarone results in decreased expression of SNAI1 protein]
CTD
PMID:26515726
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
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Map2k2
mitogen activated protein kinase kinase 2
affects expression
EXP
Amiodarone affects the expression of MAP2K2 mRNA
CTD
PMID:19483382
NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
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Mapk1
mitogen activated protein kinase 1
multiple interactions increases phosphorylation decreases phosphorylation
EXP ISO
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein] Amiodarone results in decreased phosphorylation of MAPK1 protein
CTD
PMID:26515726 PMID:31071512 PMID:34590760
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk14
mitogen activated protein kinase 14
increases phosphorylation multiple interactions
EXP
Amiodarone results in increased phosphorylation of MAPK14 protein [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]
CTD
PMID:34590760
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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Mapk3
mitogen activated protein kinase 3
increases phosphorylation decreases phosphorylation multiple interactions
EXP ISO
Amiodarone results in increased phosphorylation of MAPK3 protein Amiodarone results in decreased phosphorylation of MAPK3 protein [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]
CTD
PMID:26515726 PMID:31071512 PMID:34590760
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mapk8
mitogen-activated protein kinase 8
multiple interactions increases phosphorylation
ISO
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein] Amiodarone results in increased phosphorylation of MAPK8 protein
CTD
PMID:25073960 PMID:34259586
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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Masp1
MBL associated serine protease 1
increases expression
ISO
Amiodarone results in increased expression of MASP1 mRNA
CTD
PMID:19774075
NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
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Masp2
MBL associated serine protease 2
affects expression
EXP
Amiodarone affects the expression of MASP2 mRNA
CTD
PMID:19483382
NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
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Mbp
myelin basic protein
affects expression
EXP
Amiodarone affects the expression of MBP mRNA
CTD
PMID:25659768
NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
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Mcam
melanoma cell adhesion molecule
increases expression
ISO
Amiodarone results in increased expression of MCAM mRNA
CTD
PMID:19774075
NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
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Mcf2
MCF.2 cell line derived transforming sequence
increases expression
ISO
Amiodarone results in increased expression of MCF2 mRNA
CTD
PMID:19774075
NCBI chr X:138,414,077...138,514,828
Ensembl chr X:138,409,256...138,514,446
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Me1
malic enzyme 1
increases expression affects expression
EXP
Amiodarone results in increased expression of ME1 protein Amiodarone affects the expression of ME1 mRNA
CTD
PMID:16538043 PMID:19483382
NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
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Med11
mediator complex subunit 11
increases expression
ISO
Amiodarone results in increased expression of MED11 mRNA
CTD
PMID:19774075
NCBI chr10:55,164,322...55,165,940
Ensembl chr10:55,164,326...55,166,533
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Mef2c
myocyte enhancer factor 2C
increases expression
ISO
Amiodarone results in increased expression of MEF2C mRNA
CTD
PMID:19774075
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Mfhas1
multifunctional ROCO family signaling regulator 1
increases expression decreases expression
ISO
Amiodarone results in increased expression of MFHAS1 mRNA Amiodarone results in decreased expression of MFHAS1 mRNA
CTD
PMID:19774075 PMID:24535564
NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743
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Mfn2
mitofusin 2
increases expression
ISO
Amiodarone results in increased expression of MFN2 mRNA
CTD
PMID:24489787
NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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Mfsd1
major facilitator superfamily domain containing 1
decreases expression
EXP
Amiodarone results in decreased expression of MFSD1 mRNA
CTD
PMID:17991464
NCBI chr 2:151,846,130...151,866,168
Ensembl chr 2:151,846,146...151,867,045
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Mgat4a
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
increases expression
ISO
Amiodarone results in increased expression of MGAT4A mRNA
CTD
PMID:19774075
NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890
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Mgst1
microsomal glutathione S-transferase 1
increases expression
ISO
Amiodarone results in increased expression of MGST1 mRNA
CTD
PMID:19774075
NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
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Mgst3
microsomal glutathione S-transferase 3
increases expression
ISO
Amiodarone results in increased expression of MGST3 mRNA
CTD
PMID:24535564
NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
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Micall2
MICAL-like 2
increases expression
ISO
Amiodarone results in increased expression of MICALL2 mRNA
CTD
PMID:19774075
NCBI chr12:14,899,188...14,927,949
Ensembl chr12:14,899,157...14,927,946
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Mid2
midline 2
increases expression
ISO
Amiodarone results in increased expression of MID2 mRNA
CTD
PMID:19774075
NCBI chr X:104,354,692...104,456,757
Ensembl chr X:104,355,316...104,453,473
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Mipep
mitochondrial intermediate peptidase
increases expression
ISO
Amiodarone results in increased expression of MIPEP mRNA
CTD
PMID:24489787
NCBI chr15:34,926,198...35,051,722
Ensembl chr15:34,926,207...35,051,727
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Mir16
microRNA 16
decreases expression
EXP
Amiodarone results in decreased expression of MIR16 mRNA
CTD
PMID:17991464
NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
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Mir224
microRNA 224
decreases expression
ISO EXP
Amiodarone decreased expression of miR224 in a human hepatoma cell line Amiodarone decreased expression of miR224 in rat liver tumors
RGD
PMID:23913306 PMID:23913306
RGD:18182923 , RGD:18182923
NCBI chr X:150,065,088...150,065,169
Ensembl chr X:150,065,088...150,065,169
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Mitf
melanocyte inducing transcription factor
increases expression
ISO
Amiodarone results in increased expression of MITF mRNA
CTD
PMID:19774075
NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
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Mlx
MAX dimerization protein MLX
affects expression
EXP
Amiodarone affects the expression of MLX mRNA
CTD
PMID:18355885
NCBI chr10:86,019,216...86,024,326
Ensembl chr10:86,019,588...86,032,350
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Mlxipl
MLX interacting protein-like
decreases expression
ISO
Amiodarone results in decreased expression of MLXIPL mRNA
CTD
PMID:28962527
NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
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Mlycd
malonyl-CoA decarboxylase
increases expression
ISO
Amiodarone results in increased expression of MLYCD mRNA
CTD
PMID:24489787
NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
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Mmut
methylmalonyl-CoA mutase
affects expression
EXP
Amiodarone affects the expression of MMUT mRNA
CTD
PMID:19483382
NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
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Morn5
MORN repeat containing 5
increases expression
ISO
Amiodarone results in increased expression of MORN5 mRNA
CTD
PMID:19774075
NCBI chr 3:19,402,221...19,430,075
Ensembl chr 3:19,401,801...19,430,083
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Mpi
mannose phosphate isomerase
increases expression
ISO
Amiodarone results in increased expression of MPI mRNA
CTD
PMID:19774075
NCBI chr 8:57,947,883...57,956,205
Ensembl chr 8:57,947,893...57,956,150
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Mpo
myeloperoxidase
multiple interactions
EXP
Amiodarone promotes the reaction [Indomethacin results in increased activity of MPO protein]
CTD
PMID:18087811
NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mro
maestro
affects expression
EXP
Amiodarone affects the expression of MRO mRNA
CTD
PMID:19483382
NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044
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Mrpl10
mitochondrial ribosomal protein L10
increases expression
ISO
Amiodarone results in increased expression of MRPL10 mRNA
CTD
PMID:19774075
NCBI chr10:82,026,031...82,034,451
Ensembl chr10:82,026,031...82,034,443
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Mrpl2
mitochondrial ribosomal protein L2
affects expression
EXP
Amiodarone affects the expression of MRPL2 mRNA
CTD
PMID:19483382
NCBI chr 9:14,333,233...14,337,006
Ensembl chr 9:14,333,234...14,337,040
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mrpl9
mitochondrial ribosomal protein L9
affects expression
EXP
Amiodarone affects the expression of MRPL9 mRNA
CTD
PMID:19483382
NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095
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Mrps12
mitochondrial ribosomal protein S12
increases expression
ISO
Amiodarone results in increased expression of MRPS12 mRNA
CTD
PMID:24489787
NCBI chr 1:84,025,896...84,028,896
Ensembl chr 1:84,025,899...84,028,780
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Mrps18b
mitochondrial ribosomal protein S18B
affects expression
EXP
Amiodarone affects the expression of MRPS18B mRNA
CTD
PMID:18355885
NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260
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Ms4a14
membrane spanning 4-domains A14
increases expression
ISO
Amiodarone results in increased expression of MS4A14 mRNA
CTD
PMID:19774075
NCBI chr 1:207,949,423...207,964,937
Ensembl chr 1:207,949,426...207,964,937
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Msmo1
methylsterol monooxygenase 1
affects expression increases expression
EXP
Amiodarone affects the expression of MSMO1 mRNA Amiodarone results in increased expression of MSMO1 mRNA
CTD
PMID:18355885 PMID:22291062
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
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Mt-co3
mitochondrially encoded cytochrome c oxidase III
increases expression
EXP
Amiodarone results in increased expression of COX3 mRNA
CTD
PMID:12883083
NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382 NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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Mt1-ps3
metallothionein 1, pseudogene 3
increases expression
ISO
Amiodarone results in increased expression of MT1E mRNA
CTD
PMID:36586010
NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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Mt2A
metallothionein 2A
increases expression
ISO
Amiodarone results in increased expression of MT2A mRNA
CTD
PMID:36586010
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mtf1
metal-regulatory transcription factor 1
decreases expression
ISO
Amiodarone results in decreased expression of MTF1 mRNA
CTD
PMID:35641671
NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
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Mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
increases expression
ISO
Amiodarone results in increased expression of MTHFD2 mRNA
CTD
PMID:36586010
NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
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Mtor
mechanistic target of rapamycin kinase
multiple interactions
ISO
Amiodarone inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]
CTD
PMID:19771169
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Mttp
microsomal triglyceride transfer protein
decreases expression
ISO
Amiodarone results in decreased expression of MTTP mRNA
CTD
PMID:27089845
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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Mug2
murinoglobulin 2
affects expression
EXP
Amiodarone affects the expression of PZP mRNA
CTD
PMID:19483382
NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
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Mvd
mevalonate diphosphate decarboxylase
increases expression
EXP
Amiodarone results in increased expression of MVD mRNA
CTD
PMID:22291062
NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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Mxd1
max dimerization protein 1
increases expression
ISO
Amiodarone results in increased expression of MXD1 mRNA
CTD
PMID:19774075
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
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Myadm
myeloid-associated differentiation marker
affects expression
EXP
Amiodarone affects the expression of MYADM mRNA
CTD
PMID:19483382
NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
EXP
Amiodarone results in decreased expression of MYC mRNA
CTD
PMID:17202758
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Mycbp2
MYC binding protein 2
affects expression
EXP
Amiodarone affects the expression of MYCBP2 mRNA
CTD
PMID:19483382
NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
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Myef2
myelin expression factor 2
increases expression
ISO
Amiodarone results in increased expression of MYEF2 mRNA
CTD
PMID:19774075
NCBI chr 3:112,338,241...112,374,122
Ensembl chr 3:112,338,241...112,374,181
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Myh11
myosin heavy chain 11
increases expression
ISO
Amiodarone results in increased expression of MYH11 mRNA
CTD
PMID:19774075
NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
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Myh6
myosin heavy chain 6
decreases expression
EXP
Amiodarone results in decreased expression of MYH6 mRNA
CTD
PMID:17535870
NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
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Myh7
myosin heavy chain 7
increases expression
EXP
Amiodarone results in increased expression of MYH7 mRNA
CTD
PMID:17535870
NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
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Myl4
myosin, light chain 4
increases expression
ISO
Amiodarone results in increased expression of MYL4 mRNA
CTD
PMID:19774075
NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
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Mylk2
myosin light chain kinase 2
increases expression
ISO
Amiodarone results in increased expression of MYLK2 mRNA
CTD
PMID:19774075
NCBI chr 3:141,376,450...141,388,357
Ensembl chr 3:141,376,691...141,387,728
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Myo1d
myosin ID
affects expression
EXP
Amiodarone affects the expression of MYO1D mRNA
CTD
PMID:19483382
NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
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Myo3a
myosin IIIA
increases expression
ISO
Amiodarone results in increased expression of MYO3A mRNA
CTD
PMID:19774075
NCBI chr17:84,543,465...84,759,562
Ensembl chr17:84,543,552...84,759,042
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N4bp3
Nedd4 binding protein 3
increases expression
ISO
Amiodarone results in increased expression of N4BP3 mRNA
CTD
PMID:19774075
NCBI chr10:35,898,031...35,906,704
Ensembl chr10:35,899,096...35,907,001
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Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
increases expression
ISO
Amiodarone results in increased expression of NAA16 mRNA
CTD
PMID:19774075
NCBI chr15:54,711,620...54,770,915
Ensembl chr15:54,711,621...54,770,896
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Naa38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
affects expression
EXP
Amiodarone affects the expression of NAA38 mRNA
CTD
PMID:19483382
NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494
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Nanos1
nanos C2HC-type zinc finger 1
increases expression
ISO
Amiodarone results in increased expression of NANOS1 mRNA
CTD
PMID:19774075
NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730
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Nap1l1
nucleosome assembly protein 1-like 1
affects expression
EXP
Amiodarone affects the expression of NAP1L1 mRNA
CTD
PMID:19483382
NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
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Napsa
napsin A aspartic peptidase
decreases expression
EXP
Amiodarone results in decreased expression of NAPSA mRNA
CTD
PMID:17991464
NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094
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Nat8
N-acetyltransferase 8
affects expression
EXP
Amiodarone affects the expression of NAT8 mRNA
CTD
PMID:19483382
NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
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Ndrg2
NDRG family member 2
affects expression decreases expression
EXP
Amiodarone affects the expression of NDRG2 mRNA Amiodarone results in decreased expression of NDRG2 protein
CTD
PMID:16538043 PMID:19483382
NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
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Ndufc2
NADH:ubiquinone oxidoreductase subunit C2
increases expression
ISO
Amiodarone results in increased expression of NDUFC2 mRNA
CTD
PMID:24489787
NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189
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Ndufs1
NADH:ubiquinone oxidoreductase core subunit S1
increases expression
ISO
Amiodarone results in increased expression of NDUFS1 mRNA
CTD
PMID:24489787
NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
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Ndufs5
NADH:ubiquinone oxidoreductase subunit S5
affects expression
EXP
Amiodarone affects the expression of NDUFS5 mRNA
CTD
PMID:19483382
NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603 Ensembl chr14:135,974,034...135,979,603 Ensembl chr 2:135,974,034...135,979,603
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Ndufv3
NADH:ubiquinone oxidoreductase subunit V3
affects expression
EXP
Amiodarone affects the expression of NDUFV3 mRNA
CTD
PMID:19483382
NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074 Ensembl chr13:9,612,431...9,623,074
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Nefh
neurofilament heavy chain
decreases expression
EXP
Amiodarone results in decreased expression of NEFH mRNA
CTD
PMID:25659768
NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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Nek8
NIMA-related kinase 8
increases expression
ISO
Amiodarone results in increased expression of NEK8 mRNA
CTD
PMID:19774075
NCBI chr10:63,060,868...63,073,546
Ensembl chr10:63,061,253...63,072,416
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Neu2
neuraminidase 2
affects expression
EXP
Amiodarone affects the expression of NEU2 mRNA
CTD
PMID:19483382
NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
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Nf2
NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor
increases expression
ISO
Amiodarone results in increased expression of NF2 mRNA
CTD
PMID:19774075
NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
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Nfe2l2
NFE2 like bZIP transcription factor 2
affects expression increases expression
ISO
Amiodarone affects the expression of NFE2L2 mRNA Amiodarone results in increased expression of NFE2L2 mRNA
CTD
PMID:35641671 PMID:36586010
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfic
nuclear factor I/C
increases expression
ISO
Amiodarone results in increased expression of NFIC mRNA
CTD
PMID:19774075
NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,253,361...8,309,936
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Nfkb1
nuclear factor kappa B subunit 1
affects expression
ISO
Amiodarone affects the expression of NFKB1 mRNA
CTD
PMID:35641671
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkbia
NFKB inhibitor alpha
increases expression multiple interactions
ISO
Amiodarone results in increased expression of NFKBIA mRNA Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]
CTD
PMID:19774075 PMID:25073960
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nfkbiz
NFKB inhibitor zeta
increases expression
ISO
Amiodarone results in increased expression of NFKBIZ mRNA
CTD
PMID:19774075
NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
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Nfx1
nuclear transcription factor, X-box binding 1
affects expression
EXP
Amiodarone affects the expression of NFX1 mRNA
CTD
PMID:19483382
NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
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Niban1
niban apoptosis regulator 1
increases expression
ISO
Amiodarone results in increased expression of NIBAN1 mRNA
CTD
PMID:19774075
NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
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Nipal2
NIPA-like domain containing 2
affects expression
EXP
Amiodarone affects the expression of NIPAL2 mRNA
CTD
PMID:19483382
NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:65,774,477...65,884,807
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Nit1
nitrilase 1
affects expression
EXP
Amiodarone affects the expression of NIT1 mRNA
CTD
PMID:19483382
NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332
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Nme2
NME/NM23 nucleoside diphosphate kinase 2
affects expression
EXP
Amiodarone affects the expression of NME2 mRNA
CTD
PMID:19483382
NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
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Nme8
NME/NM23 family member 8
increases expression
ISO
Amiodarone results in increased expression of NME8 mRNA
CTD
PMID:19774075
NCBI chr17:45,237,022...45,304,948
Ensembl chr17:45,238,120...45,304,948
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Nnt
nicotinamide nucleotide transhydrogenase
increases expression
EXP
Amiodarone results in increased expression of NNT mRNA
CTD
PMID:17991464
NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
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Nol6
nucleolar protein 6
increases expression
ISO
Amiodarone results in increased expression of NOL6 mRNA
CTD
PMID:19774075
NCBI chr 5:56,259,919...56,270,540
Ensembl chr 5:56,260,830...56,270,336
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Nos1ap
nitric oxide synthase 1 adaptor protein
increases expression
ISO
Amiodarone results in increased expression of NOS1AP mRNA
CTD
PMID:19774075
NCBI chr13:82,547,799...82,820,999
Ensembl chr13:82,530,577...82,820,949
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Nos3
nitric oxide synthase 3
multiple interactions
ISO
Amiodarone promotes the reaction [NOS3 protein results in increased chemical synthesis of Nitric Oxide]
CTD
PMID:16479044
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Nppa
natriuretic peptide A
increases expression
EXP
Amiodarone results in increased expression of NPPA mRNA
CTD
PMID:17535870
NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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Npsr1
neuropeptide S receptor 1
increases expression
ISO
Amiodarone results in increased expression of NPSR1 mRNA
CTD
PMID:19774075
NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558
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Nptxr
neuronal pentraxin receptor
increases expression
ISO
Amiodarone results in increased expression of NPTXR mRNA
CTD
PMID:19774075
NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression
ISO
Amiodarone results in increased expression of NQO1 mRNA
CTD
PMID:24535564
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
increases expression
ISO
Amiodarone results in increased expression of NR1I2 mRNA
CTD
PMID:24489787
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr1i3
nuclear receptor subfamily 1, group I, member 3
affects expression
EXP
Amiodarone affects the expression of NR1I3 mRNA
CTD
PMID:19483382
NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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Nr3c1
nuclear receptor subfamily 3, group C, member 1
affects expression
EXP
Amiodarone affects the expression of NR3C1 mRNA
CTD
PMID:19483382
NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
EXP
Amiodarone results in increased expression of NR4A1 mRNA
CTD
PMID:22291062
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
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Nr4a2
nuclear receptor subfamily 4, group A, member 2
increases expression
ISO
Amiodarone results in increased expression of NR4A2 mRNA
CTD
PMID:19774075
NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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Nrep
neuronal regeneration related protein
affects expression
EXP
Amiodarone affects the expression of NREP mRNA
CTD
PMID:18355885
NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
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Nrg1
neuregulin 1
increases expression
ISO
Amiodarone results in increased expression of NRG1 mRNA
CTD
PMID:36586010
NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
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Nsdhl
NAD(P) dependent steroid dehydrogenase-like
increases expression
EXP
Amiodarone results in increased expression of NSDHL mRNA
CTD
PMID:22291062
NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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Nt5m
5',3'-nucleotidase, mitochondrial
increases expression
ISO
Amiodarone results in increased expression of NT5M mRNA
CTD
PMID:19774075
NCBI chr10:44,652,845...44,680,549
Ensembl chr10:44,652,975...44,679,150
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Ntrk3
neurotrophic receptor tyrosine kinase 3
increases expression
ISO
Amiodarone results in increased expression of NTRK3 mRNA
CTD
PMID:19774075
NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
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Nupr1
nuclear protein 1, transcriptional regulator
increases expression
ISO
Amiodarone results in increased expression of NUPR1 mRNA
CTD
PMID:15342952 PMID:17175557 PMID:17567588
NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
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Oaf
out at first homolog
affects expression
EXP
Amiodarone affects the expression of OAF mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
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Obp3
alpha-2u globulin PGCL4
affects expression
EXP
Amiodarone affects the expression of OBP3 mRNA
CTD
PMID:19483382
NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
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Ocm
oncomodulin
increases expression
ISO
Amiodarone results in increased expression of OCM mRNA
CTD
PMID:19774075
NCBI chr12:10,535,619...10,596,705
Ensembl chr12:10,586,897...10,596,707
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Ogdh
oxoglutarate dehydrogenase
affects expression
EXP
Amiodarone affects the expression of OGDH mRNA
CTD
PMID:19483382
NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
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Olr59
olfactory receptor 59
affects expression
EXP
Amiodarone affects the expression of OLR59 mRNA
CTD
PMID:19483382
NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
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Ophn1
oligophrenin 1
increases expression
ISO
Amiodarone results in increased expression of OPHN1 mRNA
CTD
PMID:19774075
NCBI chr X:63,599,746...63,976,678
Ensembl chr X:63,603,042...63,976,633
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Or2b2
olfactory receptor family 2 subfamily B member 2
increases expression
ISO
Amiodarone results in increased expression of OR2B2 mRNA
CTD
PMID:19774075
NCBI chr17:42,811,452...42,812,393
Ensembl chr17:42,809,046...42,817,534 Ensembl chr17:42,809,046...42,817,534
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Or2d2
olfactory receptor family 2 subfamily D member 2
increases expression
ISO
Amiodarone results in increased expression of OR2D2 mRNA
CTD
PMID:19774075
NCBI chr 1:160,979,415...160,980,362
Ensembl chr 1:160,979,043...160,983,787
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Or4c103b
olfactory receptor family 4 subfamily C member 103B
increases expression
ISO
Amiodarone results in increased expression of OR4C16 mRNA
CTD
PMID:19774075
NCBI chr 3:74,400,632...74,401,558
Ensembl chr 3:74,397,673...74,405,942
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Or4f5
olfactory receptor family 4 subfamily F member 5
increases expression
ISO
Amiodarone results in increased expression of OR4F5 mRNA
CTD
PMID:19774075
NCBI chr 3:98,076,440...98,080,996
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Or52n2
olfactory receptor family 52 subfamily N member 2
increases expression
ISO
Amiodarone results in increased expression of OR52N2 mRNA
CTD
PMID:19774075
NCBI chr 1:159,204,524...159,205,480
Ensembl chr 1:159,203,518...159,207,587
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Or9q2
olfactory receptor family 9 subfamily Q member 2
increases expression
ISO
Amiodarone results in increased expression of OR9Q2 mRNA
CTD
PMID:19774075
NCBI chr 1:210,933,992...210,934,936
Ensembl chr 1:210,933,727...210,937,168
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Osbp2
oxysterol binding protein 2
increases expression
ISO
Amiodarone results in increased expression of OSBP2 mRNA
CTD
PMID:19774075
NCBI chr14:78,585,088...78,746,785
Ensembl chr14:78,585,089...78,746,786
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Ostc
oligosaccharyltransferase complex non-catalytic subunit
affects expression
EXP
Amiodarone affects the expression of OSTC mRNA
CTD
PMID:19483382
NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
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Otc
ornithine transcarbamylase
affects expression
EXP
Amiodarone affects the expression of OTC mRNA
CTD
PMID:19483382
NCBI chr X:12,453,834...12,529,954
Ensembl chr X:12,453,834...12,566,918
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Oxct1
3-oxoacid CoA transferase 1
increases expression
EXP
Amiodarone results in increased expression of OXCT1 mRNA
CTD
PMID:17991464
NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
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Oxsm
3-oxoacyl-ACP synthase, mitochondrial
increases expression
ISO
Amiodarone results in increased expression of OXSM mRNA
CTD
PMID:19774075
NCBI chr15:9,210,443...9,215,852
Ensembl chr15:9,210,547...9,214,558
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Pabpc4
poly(A) binding protein, cytoplasmic 4
affects expression
EXP
Amiodarone affects the expression of PABPC4 mRNA
CTD
PMID:19483382
NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
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Paics
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
affects expression
EXP
Amiodarone affects the expression of PAICS mRNA
CTD
PMID:19483382
NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
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Park7
Parkinsonism associated deglycase
increases expression
ISO
Amiodarone results in increased expression of PARK7 mRNA
CTD
PMID:24489787
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions
ISO
[3-methyladenine co-treated with Amiodarone] results in increased cleavage of PARP1 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of PARP1 protein
CTD
PMID:21292685 PMID:23912912
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Pax3
paired box 3
increases expression
ISO
Amiodarone results in increased expression of PAX3 mRNA
CTD
PMID:19774075
NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
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Pc
pyruvate carboxylase
affects expression
EXP
Amiodarone affects the expression of PC mRNA; Amiodarone affects the expression of PCX mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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Pccb
propionyl-CoA carboxylase subunit beta
affects expression
EXP
Amiodarone affects the expression of PCCB mRNA
CTD
PMID:19483382
NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234
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Pcdh1
protocadherin 1
increases expression
ISO
Amiodarone results in increased expression of PCDH1 mRNA
CTD
PMID:19774075
NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318
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Pcdh7
protocadherin 7
increases expression
ISO
Amiodarone results in increased expression of PCDH7 mRNA
CTD
PMID:19774075
NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051 Ensembl chr14:52,475,610...52,902,051
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Pcdh8
protocadherin 8
increases expression
ISO
Amiodarone results in increased expression of PCDH8 mRNA
CTD
PMID:19774075
NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872
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Pcdhac2
protocadherin alpha subfamily C, 2
increases expression
ISO
Amiodarone results in increased expression of PCDHAC2 mRNA
CTD
PMID:19774075
Ensembl chr18:28,581,225...28,846,211
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Pcdhgc3
protocadherin gamma subfamily C, 3
increases expression
ISO
Amiodarone results in increased expression of PCDHGC3 mRNA
CTD
PMID:19774075
NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868
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Pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
increases expression
ISO
Amiodarone results in increased expression of PCK2 mRNA
CTD
PMID:24489787
NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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Pcna
proliferating cell nuclear antigen
decreases expression
EXP
Amiodarone results in decreased expression of PCNA mRNA
CTD
PMID:19224547
NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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Pcsk6
proprotein convertase subtilisin/kexin type 6
affects expression
EXP
Amiodarone affects the expression of PCSK6 mRNA
CTD
PMID:19483382
NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
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Pcsk9
proprotein convertase subtilisin/kexin type 9
increases expression
ISO
Amiodarone results in increased expression of PCSK9 mRNA
CTD
PMID:19774075
NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
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Pctp
phosphatidylcholine transfer protein
affects expression increases expression
EXP ISO
Amiodarone affects the expression of PCTP mRNA Amiodarone results in increased expression of PCTP mRNA
CTD
PMID:19483382 PMID:24489787 PMID:24535564
NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
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Pcyt1a
phosphate cytidylyltransferase 1A, choline
increases expression
EXP
Amiodarone results in increased expression of PCYT1A mRNA
CTD
PMID:22291062
NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
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Pdcd10
programmed cell death 10
increases expression
ISO
Amiodarone results in increased expression of PDCD10 mRNA
CTD
PMID:19774075
NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
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Pdcl3
phosducin-like 3
affects expression
EXP
Amiodarone affects the expression of PDCL3 mRNA
CTD
PMID:19483382
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
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Pde6g
phosphodiesterase 6G
increases expression
ISO
Amiodarone results in increased expression of PDE6G mRNA
CTD
PMID:19774075
NCBI chr10:105,721,502...105,726,150
Ensembl chr10:105,721,682...105,726,719
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Pde7b
phosphodiesterase 7B
increases expression
ISO
Amiodarone results in increased expression of PDE7B mRNA
CTD
PMID:19774075
NCBI chr 1:15,174,001...15,493,267
Ensembl chr 1:15,182,704...15,492,900
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Pdf
peptide deformylase (mitochondrial)
increases expression
ISO
Amiodarone results in increased expression of PDF mRNA
CTD
PMID:19774075
NCBI chr19:34,949,408...34,951,621
Ensembl chr19:34,948,256...34,951,515
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Pdgfrl
platelet-derived growth factor receptor-like
increases expression
ISO
Amiodarone results in increased expression of PDGFRL mRNA
CTD
PMID:19774075
NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
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Pdia3
protein disulfide isomerase family A, member 3
affects expression
EXP
Amiodarone affects the expression of PDIA3 mRNA
CTD
PMID:19483382
NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
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Pdia6
protein disulfide isomerase family A, member 6
affects expression
EXP
Amiodarone affects the expression of PDIA6 mRNA
CTD
PMID:19483382
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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Pdk4
pyruvate dehydrogenase kinase 4
increases expression
ISO
Amiodarone results in increased expression of PDK4 mRNA
CTD
PMID:24489787
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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Pdlim2
PDZ and LIM domain 2
increases expression
ISO
Amiodarone results in increased expression of PDLIM2 mRNA
CTD
PMID:19774075
NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
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Pdss1
decaprenyl diphosphate synthase subunit 1
increases expression
ISO
Amiodarone results in increased expression of PDSS1 mRNA
CTD
PMID:24489787
NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
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Pdss2
decaprenyl diphosphate synthase subunit 2
increases expression
ISO
Amiodarone results in increased expression of PDSS2 mRNA
CTD
PMID:24489787
NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
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Pdyn
prodynorphin
increases expression
ISO
Amiodarone results in increased expression of PDYN mRNA
CTD
PMID:19774075
NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
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Pdzrn3
PDZ domain containing RING finger 3
increases expression
ISO
Amiodarone results in increased expression of PDZRN3 mRNA
CTD
PMID:24535564
NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959
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Pecr
peroxisomal trans-2-enoyl-CoA reductase
affects expression
EXP
Amiodarone affects the expression of PECR mRNA
CTD
PMID:18355885
NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
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Per1
period circadian regulator 1
increases expression
ISO
Amiodarone results in increased expression of PER1 mRNA
CTD
PMID:19774075
NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
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Pex1
peroxisomal biogenesis factor 1
increases expression
ISO
Amiodarone results in increased expression of PEX1 mRNA
CTD
PMID:24489787
NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921
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Pex10
peroxisomal biogenesis factor 10
increases expression
ISO
Amiodarone results in increased expression of PEX10 mRNA
CTD
PMID:24489787
NCBI chr 5:165,627,799...165,632,965
Ensembl chr 5:165,627,799...165,632,965
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Pex11a
peroxisomal biogenesis factor 11 alpha
increases expression
ISO
Amiodarone results in increased expression of PEX11A mRNA
CTD
PMID:24489787
NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
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Pex11b
peroxisomal biogenesis factor 11 beta
increases expression
ISO
Amiodarone results in increased expression of PEX11B mRNA
CTD
PMID:24489787
NCBI chr 2:184,172,041...184,180,972
Ensembl chr 2:184,172,004...184,181,495
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Pex12
peroxisomal biogenesis factor 12
increases expression
ISO
Amiodarone results in increased expression of PEX12 mRNA
CTD
PMID:24489787
NCBI chr10:68,095,776...68,103,812
Ensembl chr10:68,095,776...68,099,428
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Pex19
peroxisomal biogenesis factor 19
affects expression increases expression
EXP ISO
Amiodarone affects the expression of PEX19 mRNA Amiodarone results in increased expression of PEX19 mRNA
CTD
PMID:19483382 PMID:24489787
NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
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Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
increases expression
ISO
Amiodarone results in increased expression of PFKFB1 mRNA
CTD
PMID:24535564
NCBI chr X:19,508,522...19,562,165
Ensembl chr X:19,508,546...19,562,182
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Pfkm
phosphofructokinase, muscle
multiple interactions
ISO
PFKM protein mutant form results in increased susceptibility to [Cyclosporine co-treated with Amiodarone]
CTD
PMID:30792690
NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
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Pgam1
phosphoglycerate mutase 1
affects expression
EXP
Amiodarone affects the expression of PGAM1 mRNA
CTD
PMID:19483382
NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
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Pgk2
phosphoglycerate kinase 2
increases expression
ISO
Amiodarone results in increased expression of PGK2 mRNA
CTD
PMID:19774075
NCBI chr 9:20,480,367...20,481,933
Ensembl chr 9:20,480,203...20,571,481
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Pgrmc1
progesterone receptor membrane component 1
affects expression
EXP
Amiodarone affects the expression of PGRMC1 mRNA
CTD
PMID:19483382
NCBI chr X:115,832,865...115,841,060
Ensembl chr X:115,832,884...115,888,682
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Pgs1
phosphatidylglycerophosphate synthase 1
increases expression
EXP
Amiodarone results in increased expression of PGS1 mRNA
CTD
PMID:22291062
NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254
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Phf20l1
PHD finger protein 20-like 1
increases expression
ISO
Amiodarone results in increased expression of PHF20L1 mRNA
CTD
PMID:19774075
NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526
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Phf5a
PHD finger protein 5A
increases expression
ISO
Amiodarone results in increased expression of PHF5A mRNA
CTD
PMID:19774075
NCBI chr 7:113,378,469...113,385,035
Ensembl chr 7:113,378,471...113,385,460
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Phka1
phosphorylase kinase regulatory subunit alpha 1
increases expression
ISO
Amiodarone results in increased expression of PHKA1 mRNA
CTD
PMID:19774075
NCBI chr X:67,601,302...67,738,504
Ensembl chr X:67,601,302...67,738,455
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Phyh
phytanoyl-CoA 2-hydroxylase
affects expression
EXP
Amiodarone affects the expression of PHYH mRNA
CTD
PMID:19483382
NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
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Piga
phosphatidylinositol glycan anchor biosynthesis, class A
increases expression
ISO
Amiodarone results in increased expression of PIGA mRNA
CTD
PMID:19774075
NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
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Pigp
phosphatidylinositol glycan anchor biosynthesis, class P
affects expression
EXP
Amiodarone affects the expression of PIGP mRNA
CTD
PMID:19483382
NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321
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Pip5k1a
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha
increases expression
ISO
Amiodarone results in increased expression of PIP5K1A mRNA
CTD
PMID:19774075
NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
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Pklr
pyruvate kinase L/R
affects expression
EXP
Amiodarone affects the expression of PKLR mRNA
CTD
PMID:19483382
NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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Pla2g15
phospholipase A2, group XV
affects expression
ISO
Amiodarone affects the expression of PLA2G15 mRNA
CTD
PMID:29248575
NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
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Pla2g2a
phospholipase A2 group IIA
increases expression
EXP
Amiodarone results in increased expression of PLA2G2A mRNA
CTD
PMID:25580480
NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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Pla2g4a
phospholipase A2 group 4A
decreases expression
EXP
Amiodarone results in decreased expression of PLA2G4A mRNA
CTD
PMID:22291062
NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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Pla2g7
phospholipase A2 group VII
increases expression
EXP
Amiodarone results in increased expression of PLA2G7 mRNA
CTD
PMID:25580480
NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
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Plaa
phospholipase A2, activating protein
increases expression
ISO
Amiodarone results in increased expression of PLAA mRNA
CTD
PMID:19774075
NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
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Plaat3
phospholipase A and acyltransferase 3
increases expression
ISO
Amiodarone results in increased expression of PLAAT3 mRNA
CTD
PMID:24535564
NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
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Plac8l1
PLAC8-like 1
increases expression
ISO
Amiodarone results in increased expression of PLAC8L1 mRNA
CTD
PMID:19774075
NCBI chr18:34,167,667...34,192,137
Ensembl chr18:34,168,864...34,190,800
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Plbd1
phospholipase B domain containing 1
affects expression
EXP
Amiodarone affects the expression of PLBD1 mRNA
CTD
PMID:19483382
NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
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Plcg1
phospholipase C, gamma 1
decreases expression
EXP
Amiodarone results in decreased expression of PLCG1 protein
CTD
PMID:21224497
NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
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Pld1
phospholipase D1
decreases expression
EXP
Amiodarone results in decreased expression of PLD1 mRNA
CTD
PMID:22291062
NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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Plekhg4
pleckstrin homology and RhoGEF domain containing G4
increases expression
ISO
Amiodarone results in increased expression of PLEKHG4 mRNA
CTD
PMID:19774075
NCBI chr19:33,251,788...33,266,490
Ensembl chr19:33,249,706...33,266,357
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Plg
plasminogen
affects expression
EXP
Amiodarone affects the expression of PLG mRNA
CTD
PMID:19483382
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
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Pls1
plastin 1
increases expression
ISO
Amiodarone results in increased expression of PLS1 mRNA
CTD
PMID:19774075
NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
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Pls3
plastin 3
affects expression
EXP
Amiodarone affects the expression of PLS3 mRNA
CTD
PMID:19483382
NCBI chr X:111,589,193...111,683,908
Ensembl chr X:111,589,254...111,683,891
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Pltp
phospholipid transfer protein
increases expression
ISO
Amiodarone results in increased expression of PLTP mRNA
CTD
PMID:24535564
NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
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Pmm1
phosphomannomutase 1
increases expression
ISO
Amiodarone results in increased expression of PMM1 mRNA
CTD
PMID:24489787
NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
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Pmvk
phosphomevalonate kinase
increases expression
ISO EXP
Amiodarone results in increased expression of PMVK mRNA
CTD
PMID:22291062 PMID:24535564
NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
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Podn
podocan
increases expression
ISO
Amiodarone results in increased expression of PODN mRNA
CTD
PMID:19774075
NCBI chr 5:122,774,536...122,796,755
Ensembl chr 5:122,776,549...122,881,287
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Poll
DNA polymerase lambda
increases expression
ISO
Amiodarone results in increased expression of POLL mRNA
CTD
PMID:19774075
NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
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Pon2
paraoxonase 2
affects expression
EXP
Amiodarone affects the expression of PON2 mRNA
CTD
PMID:19483382
NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
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Por
cytochrome p450 oxidoreductase
affects expression
EXP
Amiodarone affects the expression of POR mRNA
CTD
PMID:18355885
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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Poteh
POTE ankyrin domain family member H
increases expression
ISO
Amiodarone results in increased expression of POTEH mRNA
CTD
PMID:19774075
NCBI chr15:17,131,582...17,219,924
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Ppara
peroxisome proliferator activated receptor alpha
increases expression decreases expression increases response to substance
EXP ISO
Amiodarone results in increased expression of PPARA mRNA Amiodarone results in decreased expression of PPARA mRNA PPARA protein results in increased susceptibility to Amiodarone
CTD
PMID:15265979 PMID:19224547 PMID:24489787 PMID:30685923 PMID:32084307
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions decreases expression increases expression
ISO
[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of SCD mRNA]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]; Amiodarone binds to and results in increased activity of PPARG protein Amiodarone results in decreased expression of PPARG mRNA Amiodarone results in increased expression of PPARG mRNA
CTD
PMID:21123845 PMID:24489787 PMID:35641671
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ppargc1a
PPARG coactivator 1 alpha
increases expression
ISO
Amiodarone results in increased expression of PPARGC1A mRNA
CTD
PMID:27089845
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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Ppargc1b
PPARG coactivator 1 beta
increases expression
ISO
Amiodarone results in increased expression of PPARGC1B mRNA
CTD
PMID:24489787
NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
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Ppdpf
pancreatic progenitor cell differentiation and proliferation factor
affects expression
EXP
Amiodarone affects the expression of PPDPF mRNA
CTD
PMID:19483382
NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036
G
Ppm1b
protein phosphatase, Mg2+/Mn2+ dependent, 1B
increases expression
ISO
Amiodarone results in increased expression of PPM1B mRNA
CTD
PMID:19774075
NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
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Ppp1r15a
protein phosphatase 1, regulatory subunit 15A
increases expression
ISO
Amiodarone results in increased expression of PPP1R15A mRNA
CTD
PMID:19774075 PMID:36586010
NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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Ppp2r5c
protein phosphatase 2, regulatory subunit B', gamma
increases expression
ISO
Amiodarone results in increased expression of PPP2R5C mRNA
CTD
PMID:19774075
NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
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Ppp3r1
protein phosphatase 3, regulatory subunit B, alpha
increases expression
ISO
Amiodarone results in increased expression of PPP3R1 mRNA
CTD
PMID:19774075
NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
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Prdm2
PR/SET domain 2
increases expression
ISO
Amiodarone results in increased expression of PRDM2 mRNA
CTD
PMID:19774075
NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
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Prdm8
PR/SET domain 8
increases expression
ISO
Amiodarone results in increased expression of PRDM8 mRNA
CTD
PMID:19774075
NCBI chr14:11,403,202...11,424,059
Ensembl chr14:11,404,407...11,410,993
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Prdx1
peroxiredoxin 1
decreases expression
ISO
Amiodarone results in decreased expression of PRDX1 mRNA
CTD
PMID:36586010
NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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Prdx2
peroxiredoxin 2
affects expression
EXP
Amiodarone affects the expression of PRDX2 mRNA
CTD
PMID:19483382
NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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Prdx3
peroxiredoxin 3
increases expression
ISO
Amiodarone results in increased expression of PRDX3 mRNA
CTD
PMID:24489787
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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Prdx6
peroxiredoxin 6
affects expression
EXP
Amiodarone affects the expression of PRDX6 mRNA
CTD
PMID:19483382
NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
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Prim2
DNA primase subunit 2
increases expression
ISO
Amiodarone results in increased expression of PRIM2 mRNA
CTD
PMID:19774075
NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030
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Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
increases phosphorylation
ISO
Amiodarone results in increased phosphorylation of PRKAA1 protein
CTD
PMID:23912912
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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Prkaa2
protein kinase AMP-activated catalytic subunit alpha 2
increases phosphorylation
ISO
Amiodarone results in increased phosphorylation of PRKAA2 protein
CTD
PMID:23912912
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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Prl
prolactin
decreases expression
EXP
Amiodarone results in decreased expression of PRL mRNA
CTD
PMID:3427795
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Prmt1
protein arginine methyltransferase 1
increases expression
ISO
Amiodarone results in increased expression of PRMT1 mRNA
CTD
PMID:19774075
NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
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Proc
protein C, inactivator of coagulation factors Va and VIIIa
affects expression
EXP
Amiodarone affects the expression of PROC mRNA
CTD
PMID:19483382
NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
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Proser2
proline and serine rich 2
increases expression
ISO
Amiodarone results in increased expression of PROSER2 mRNA
CTD
PMID:19774075
NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825
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Prox1
prospero homeobox 1
increases expression
ISO
Amiodarone results in increased expression of PROX1 mRNA
CTD
PMID:19774075
NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
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Prpsap1
phosphoribosyl pyrophosphate synthetase-associated protein 1
affects expression
EXP
Amiodarone affects the expression of PRPSAP1 mRNA
CTD
PMID:19483382
NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
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Prr19
proline rich 19
increases expression
ISO
Amiodarone results in increased expression of PRR19 mRNA
CTD
PMID:19774075
NCBI chr 1:80,884,529...80,890,712
Ensembl chr 1:80,887,151...80,890,168
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Psca
prostate stem cell antigen
decreases expression
EXP
Amiodarone results in decreased expression of PSCA mRNA
CTD
PMID:17991464
NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746
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Psen1
presenilin 1
increases expression
ISO
Amiodarone results in increased expression of PSEN1 mRNA
CTD
PMID:19774075
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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Psip1
PC4 and SRSF1 interacting protein 1
increases expression
ISO
Amiodarone results in increased expression of PSIP1 mRNA
CTD
PMID:19774075
NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257
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Psma6
proteasome 20S subunit alpha 6
affects expression
EXP
Amiodarone affects the expression of PSMA6 mRNA
CTD
PMID:19483382
NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
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Psmb1
proteasome 20S subunit beta 1
affects expression
EXP
Amiodarone affects the expression of PSMB1 mRNA
CTD
PMID:19483382
NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
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Psmb3
proteasome 20S subunit beta 3
affects expression
EXP
Amiodarone affects the expression of PSMB3 mRNA
CTD
PMID:19483382
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
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Psmc1
proteasome 26S subunit, ATPase 1
affects expression
EXP
Amiodarone affects the expression of PSMC1 mRNA
CTD
PMID:19483382
NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
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Psmc3
proteasome 26S subunit, ATPase 3
affects expression
EXP
Amiodarone affects the expression of PSMC3 mRNA
CTD
PMID:19483382
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
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Psmc5
proteasome 26S subunit, ATPase 5
affects expression
EXP
Amiodarone affects the expression of PSMC5 mRNA
CTD
PMID:19483382
NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
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Psmd1
proteasome 26S subunit, non-ATPase 1
affects expression
EXP
Amiodarone affects the expression of PSMD1 mRNA
CTD
PMID:19483382
NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
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Psmd11
proteasome 26S subunit, non-ATPase 11
increases expression
ISO
Amiodarone results in increased expression of PSMD11 mRNA
CTD
PMID:19774075
NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
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Psmd4
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
affects expression
EXP
Amiodarone affects the expression of PSMD4 mRNA
CTD
PMID:19483382
NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
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Ptgr1
prostaglandin reductase 1
increases expression
ISO
Amiodarone results in increased expression of PTGR1 mRNA
CTD
PMID:19774075
NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
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Ptgs2
prostaglandin-endoperoxide synthase 2
increases expression
ISO
Amiodarone results in increased expression of PTGS2 mRNA
CTD
PMID:19774075
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptms
parathymosin
affects expression
EXP
Amiodarone affects the expression of PTMS mRNA
CTD
PMID:19483382
NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
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Ptpn3
protein tyrosine phosphatase, non-receptor type 3
increases expression
ISO
Amiodarone results in increased expression of PTPN3 mRNA
CTD
PMID:19774075
NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
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Ptprf
protein tyrosine phosphatase, receptor type, F
increases expression affects expression
ISO EXP
Amiodarone results in increased expression of PTPRF mRNA Amiodarone affects the expression of PTPRF mRNA
CTD
PMID:19483382 PMID:19774075
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
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Ptprn
protein tyrosine phosphatase, receptor type, N
increases expression
ISO
Amiodarone results in increased expression of PTPRN mRNA
CTD
PMID:19774075
NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
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Pttg1ip
PTTG1 interacting protein
affects expression
EXP
Amiodarone affects the expression of PTTG1IP mRNA
CTD
PMID:19483382
NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
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Pxmp4
peroxisomal membrane protein 4
increases expression
ISO
Amiodarone results in increased expression of PXMP4 mRNA
CTD
PMID:24489787
NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651
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Pygl
glycogen phosphorylase L
affects expression
EXP
Amiodarone affects the expression of PYGL mRNA
CTD
PMID:19483382
NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
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Pygo1
pygopus family PHD finger 1
increases expression
ISO
Amiodarone results in increased expression of PYGO1 mRNA
CTD
PMID:19774075
NCBI chr 8:73,666,210...73,684,873
Ensembl chr 8:73,665,593...73,684,869
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Qpct
glutaminyl-peptide cyclotransferase
increases expression
ISO
Amiodarone results in increased expression of QPCT mRNA
CTD
PMID:24535564
NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711
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Rab5if
RAB5 interacting factor
affects expression
EXP
Amiodarone affects the expression of RAB5IF mRNA
CTD
PMID:19483382
NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012
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Rab9b
RAB9B, member RAS oncogene family
increases expression
ISO
Amiodarone results in increased expression of RAB9B mRNA
CTD
PMID:19774075
NCBI chr X:100,220,897...100,231,591
Ensembl chr X:100,220,894...100,231,701
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Rac3
Rac family small GTPase 3
increases expression
ISO
Amiodarone results in increased expression of RAC3 mRNA
CTD
PMID:19774075
NCBI chr10:106,002,808...106,005,243
Ensembl chr10:105,993,087...106,005,260
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Rad51b
RAD51 paralog B
increases expression
ISO
Amiodarone results in increased expression of RAD51B mRNA
CTD
PMID:24535564
NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
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Rbbp8
RB binding protein 8, endonuclease
increases expression
ISO
Amiodarone results in increased expression of RBBP8 mRNA
CTD
PMID:19774075
NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
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Rbks
ribokinase
increases expression
ISO
Amiodarone results in increased expression of RBKS mRNA
CTD
PMID:19774075
NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290
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Rbl2
RB transcriptional corepressor like 2
affects expression
EXP
Amiodarone affects the expression of RBL2 mRNA
CTD
PMID:18355885
NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
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Rbm33
RNA binding motif protein 33
increases expression
ISO
Amiodarone results in increased expression of RBM33 mRNA
CTD
PMID:19774075
NCBI chr 4:6,980,807...7,088,334
Ensembl chr 4:6,983,970...7,089,918
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Rbpms
RNA binding protein, mRNA processing factor
increases expression
ISO
Amiodarone results in increased expression of RBPMS mRNA
CTD
PMID:19774075
NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
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Rcc1l
RCC1 like
increases expression
ISO
Amiodarone results in increased expression of RCC1L mRNA
CTD
PMID:19774075
NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036
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Rcn3
reticulocalbin 3
increases expression
ISO
Amiodarone results in increased expression of RCN3 mRNA
CTD
PMID:19774075
NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725
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Rdh8
retinol dehydrogenase 8
increases expression
ISO
Amiodarone results in increased expression of RDH8 mRNA
CTD
PMID:19774075
NCBI chr 8:19,353,191...19,360,462
Ensembl chr 8:19,353,191...19,360,462
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Relb
RELB proto-oncogene, NF-kB subunit
increases expression
ISO
Amiodarone results in increased expression of RELB mRNA
CTD
PMID:19774075
NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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Repin1
replication initiator 1
increases expression
ISO
Amiodarone results in increased expression of REPIN1 mRNA
CTD
PMID:19774075
NCBI chr 4:77,548,724...77,554,242
Ensembl chr 4:77,548,849...77,554,257
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Retsat
retinol saturase
increases expression
ISO
Amiodarone results in increased expression of RETSAT mRNA
CTD
PMID:24535564
NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
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Rgn
regucalcin
decreases expression
EXP
Amiodarone results in decreased expression of RGN mRNA
CTD
PMID:12883083
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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Rgs6
regulator of G-protein signaling 6
increases expression
ISO
Amiodarone results in increased expression of RGS6 mRNA
CTD
PMID:19774075
NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753
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Rhebl1
RHEB like 1
increases expression
ISO
Amiodarone results in increased expression of RHEBL1 mRNA
CTD
PMID:19774075
NCBI chr 7:130,026,255...130,031,127
Ensembl chr 7:130,026,341...130,030,248
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Rida
reactive intermediate imine deaminase A homolog
affects expression
EXP
Amiodarone affects the expression of RIDA mRNA
CTD
PMID:19483382
NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
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Rin3
Ras and Rab interactor 3
increases expression
ISO
Amiodarone results in increased expression of RIN3 mRNA
CTD
PMID:19774075
NCBI chr 6:121,431,776...121,540,956
Ensembl chr 6:121,431,339...121,540,957
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Rnase4
ribonuclease A family member 4
affects expression
EXP
Amiodarone affects the expression of RNASE4 mRNA
CTD
PMID:19483382
NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
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Rnf103
ring finger protein 103
affects expression
EXP
Amiodarone affects the expression of RNF103 mRNA
CTD
PMID:19483382
NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919
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Rnf146
ring finger protein 146
increases expression
ISO
Amiodarone results in increased expression of RNF146 mRNA
CTD
PMID:19774075
NCBI chr 1:28,458,864...28,475,758
Ensembl chr 1:28,458,887...28,475,923
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Rnf19a
ring finger protein 19A, RBR E3 ubiquitin protein ligase
increases expression
ISO
Amiodarone results in increased expression of RNF19A mRNA
CTD
PMID:19774075
NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
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Rnf212
ring finger protein 212
increases expression
ISO
Amiodarone results in increased expression of RNF212 mRNA
CTD
PMID:19774075
NCBI chr14:949,397...988,377
Ensembl chr14:949,448...987,831
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Rnf6
ring finger protein 6
increases expression
ISO
Amiodarone results in increased expression of RNF6 mRNA
CTD
PMID:19774075
NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847
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Rnf8
ring finger protein 8
increases expression
ISO
Amiodarone results in increased expression of RNF8 mRNA
CTD
PMID:19774075
NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491
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Rnps1
RNA binding protein with serine rich domain 1
affects expression
EXP
Amiodarone affects the expression of RNPS1 mRNA
CTD
PMID:19483382
NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858
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Rpl11
ribosomal protein L11
affects expression
EXP
Amiodarone affects the expression of RPL11 mRNA
CTD
PMID:19483382
NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
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Rpl13
ribosomal protein L13
affects expression
EXP
Amiodarone affects the expression of RPL13 mRNA
CTD
PMID:19483382
NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
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Rpl15
ribosomal protein L15
affects expression
EXP
Amiodarone affects the expression of RPL15 mRNA
CTD
PMID:19483382
NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
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Rpl17
ribosomal protein L17
affects expression
EXP
Amiodarone affects the expression of RPL17 mRNA
CTD
PMID:19483382
NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
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Rpl23
ribosomal protein L23
affects expression
EXP
Amiodarone affects the expression of RPL23 mRNA
CTD
PMID:19483382
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
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Rpl3
ribosomal protein L3
affects expression
EXP
Amiodarone affects the expression of RPL3 mRNA
CTD
PMID:19483382
NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
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Rpl32
ribosomal protein L32
affects expression
EXP
Amiodarone affects the expression of RPL32 mRNA
CTD
PMID:19483382
NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
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Rpl36a
ribosomal protein L36A
increases expression
ISO
Amiodarone results in increased expression of RPL36A mRNA
CTD
PMID:19774075
NCBI chr X:97,766,179...97,768,892
Ensembl chr X:97,766,179...97,768,892
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Rpl4
ribosomal protein L4
affects expression
EXP
Amiodarone affects the expression of RPL4 mRNA
CTD
PMID:19483382
NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
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Rpn2
ribophorin II
affects expression
EXP
Amiodarone affects the expression of RPN2 mRNA
CTD
PMID:19483382
NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
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Rps14
ribosomal protein S14
affects expression
EXP
Amiodarone affects the expression of RPS14 mRNA
CTD
PMID:19483382
NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
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Rps18
ribosomal protein S18
affects expression
EXP
Amiodarone affects the expression of RPS18 mRNA
CTD
PMID:19483382
NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146 Ensembl chr20:101,204,500...101,205,146
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Rps19
ribosomal protein S19
affects expression
EXP
Amiodarone affects the expression of RPS19 mRNA
CTD
PMID:19483382
NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
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Rps20
ribosomal protein S20
affects expression
EXP
Amiodarone affects the expression of RPS20 mRNA
CTD
PMID:19483382
NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475 Ensembl chr 9:16,819,304...16,820,475 Ensembl chr 3:16,819,304...16,820,475
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Rps3a
ribosomal protein S3a
affects expression
EXP
Amiodarone affects the expression of RPS3A mRNA
CTD
PMID:19483382
NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
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Rps6
ribosomal protein S6
affects expression
EXP
Amiodarone affects the expression of RPS6 mRNA
CTD
PMID:19483382
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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Rps6kb1
ribosomal protein S6 kinase B1
decreases phosphorylation
ISO
Amiodarone results in decreased phosphorylation of RPS6KB1 protein
CTD
PMID:23912912 PMID:25881747
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Rps8
ribosomal protein S8
affects expression
EXP
Amiodarone affects the expression of RPS8 mRNA
CTD
PMID:19483382
NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
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Rras2
RAS related 2
affects expression
EXP
Amiodarone affects the expression of RRAS2 mRNA
CTD
PMID:19483382
NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
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RT1-Hb-ps1
RT1 class II, locus Hb, pseudogene 1
increases expression
ISO
Amiodarone results in increased expression of HLA-DPB1 mRNA
CTD
PMID:19774075
NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
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RT1-S3
RT1 class Ib, locus S3
affects expression
EXP
Amiodarone affects the expression of RT1-S3 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
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Rtn4
reticulon 4
increases expression
ISO
Amiodarone results in increased expression of RTN4 mRNA
CTD
PMID:24535564
NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
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Rundc3a
RUN domain containing 3A
increases expression
ISO
Amiodarone results in increased expression of RUNDC3A mRNA
CTD
PMID:19774075
NCBI chr10:87,352,624...87,361,767
Ensembl chr10:87,352,646...87,361,765
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Rxrg
retinoid X receptor gamma
increases expression
ISO
Amiodarone results in increased expression of RXRG mRNA
CTD
PMID:24489787
NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
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S100a10
S100 calcium binding protein A10
increases expression
ISO
Amiodarone results in increased expression of S100A10 mRNA
CTD
PMID:24535564
NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
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S1pr1
sphingosine-1-phosphate receptor 1
affects expression
EXP
Amiodarone affects the expression of S1PR1 mRNA
CTD
PMID:19483382
NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
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Sardh
sarcosine dehydrogenase
increases expression
ISO
Amiodarone results in increased expression of SARDH mRNA
CTD
PMID:19774075
NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
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Sbspon
somatomedin B and thrombospondin, type 1 domain containing
affects expression
EXP
Amiodarone affects the expression of SBSPON mRNA
CTD
PMID:19483382
NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420
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Sc5d
sterol-C5-desaturase
increases expression
EXP
Amiodarone results in increased expression of SC5D mRNA
CTD
PMID:22291062
NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
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Sccpdh
saccharopine dehydrogenase (putative)
decreases expression
EXP
Amiodarone results in decreased expression of SCCPDH mRNA
CTD
PMID:17991464
NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222
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Scd
stearoyl-CoA desaturase
multiple interactions decreases expression increases expression
ISO EXP
[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of SCD mRNA]; SCD protein affects the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine] Amiodarone results in decreased expression of SCD1 mRNA; Amiodarone results in decreased expression of SCD1 protein Amiodarone results in increased expression of SCD1 mRNA
CTD
PMID:17202758 PMID:19224547 PMID:21123845 PMID:29248575 PMID:32535746 PMID:34259586 More...
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Scgb1a1
secretoglobin family 1A member 1
increases expression
EXP
Amiodarone results in increased expression of SCGB1A1 protein
CTD
PMID:32909452
NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
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Scimp
SLP adaptor and CSK interacting membrane protein
increases expression
ISO
Amiodarone results in increased expression of SCIMP mRNA
CTD
PMID:19774075
NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171
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Scn1b
sodium voltage-gated channel beta subunit 1
decreases expression
ISO
Amiodarone results in decreased expression of SCN1B mRNA
CTD
PMID:15520326
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
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Scn4a
sodium voltage-gated channel alpha subunit 4
decreases expression
ISO
Amiodarone results in decreased expression of SCN4A mRNA
CTD
PMID:15520326
NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545
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Scn5a
sodium voltage-gated channel alpha subunit 5
decreases expression affects response to substance
ISO
Amiodarone results in decreased expression of SCN5A mRNA SCN5A polymorphism affects the susceptibility to Amiodarone
CTD
PMID:15520326 PMID:33824187
NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
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Sdc2
syndecan 2
affects expression
EXP
Amiodarone affects the expression of SDC2 mRNA
CTD
PMID:19483382
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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Sdhc
succinate dehydrogenase complex subunit C
affects expression
EXP
Amiodarone affects the expression of SDHC mRNA
CTD
PMID:19483382
NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253
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Sdhd
succinate dehydrogenase complex subunit D
affects expression
EXP
Amiodarone affects the expression of SDHD mRNA
CTD
PMID:19483382
NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238
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Sdr9c7
short chain dehydrogenase/reductase family 9C, member 7
decreases expression
ISO
Amiodarone results in decreased expression of SDR9C7 mRNA
CTD
PMID:24535564
NCBI chr 7:63,703,788...63,720,325
Ensembl chr 7:63,707,071...63,721,480
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Sema3d
semaphorin 3D
increases expression
ISO
Amiodarone results in increased expression of SEMA3D mRNA
CTD
PMID:19774075
NCBI chr 4:22,316,769...22,505,930
Ensembl chr 4:22,316,779...22,505,930
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Sema4d
semaphorin 4D
increases expression
ISO
Amiodarone results in increased expression of SEMA4D mRNA
CTD
PMID:19774075
NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138
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Sema6b
semaphorin 6B
increases expression
ISO
Amiodarone results in increased expression of SEMA6B mRNA
CTD
PMID:19774075
NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521
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Semg1
semenogelin 1
increases expression
ISO
Amiodarone results in increased expression of SEMG1 mRNA
CTD
PMID:19774075
NCBI chr 3:152,910,033...152,912,882
Ensembl chr 3:152,910,034...152,912,882
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Serinc3
serine incorporator 3
affects expression
EXP
Amiodarone affects the expression of SERINC3 mRNA
CTD
PMID:19483382
NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
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Serpina1
serpin family A member 1
affects expression
EXP
Amiodarone affects the expression of SERPINA1 mRNA
CTD
PMID:19483382
NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
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Serpina10
serpin family A member 10
increases expression affects expression
ISO EXP
Amiodarone results in increased expression of SERPINA10 mRNA Amiodarone affects the expression of SERPINA10 mRNA
CTD
PMID:19483382 PMID:19774075
NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544
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Serpina11
serpin family A member 11
decreases expression
ISO
Amiodarone results in decreased expression of SERPINA11 mRNA
CTD
PMID:24535564
NCBI chr 6:122,903,246...122,912,695
Ensembl chr 6:122,903,250...122,912,670
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Serpina12
serpin family A member 12
decreases expression
ISO
Amiodarone results in decreased expression of SERPINA12 mRNA
CTD
PMID:24535564
NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271
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Serpina4
serpin family A member 4
affects expression
EXP
Amiodarone affects the expression of SERPINA4 mRNA
CTD
PMID:19483382
NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082
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Serpina9
serpin family A member 9
decreases expression
ISO
Amiodarone results in decreased expression of SERPINA9 mRNA
CTD
PMID:24535564
NCBI chr 6:122,918,819...122,936,000
Ensembl chr 6:122,918,880...122,936,000
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Serpinb1a
serpin family B member 1A
increases expression
ISO
Amiodarone results in increased expression of SERPINB1A mRNA
CTD
PMID:24535564
NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
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Serpinf2
serpin family F member 2
affects expression
EXP
Amiodarone affects the expression of SERPINF2 mRNA
CTD
PMID:19483382
NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
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Sertad3
SERTA domain containing 3
increases expression
ISO
Amiodarone results in increased expression of SERTAD3 mRNA
CTD
PMID:19774075
NCBI chr 1:82,763,535...82,767,271
Ensembl chr 1:82,763,149...82,769,001
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Sesn2
sestrin 2
increases expression
ISO
Amiodarone results in increased expression of SESN2 mRNA
CTD
PMID:19774075
NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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Sftpb
surfactant protein B
increases metabolic processing
ISO
Amiodarone results in increased metabolism of SFTPB protein
CTD
PMID:25163675
NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
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Sftpc
surfactant protein C
increases metabolic processing
ISO
Amiodarone results in increased metabolism of SFTPC protein
CTD
PMID:25163675
NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
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Sfxn1
sideroflexin 1
affects expression
EXP
Amiodarone affects the expression of SFXN1 mRNA
CTD
PMID:19483382
NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
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Sh2d1a
SH2 domain containing 1A
increases expression
ISO
Amiodarone results in increased expression of SH2D1A mRNA
CTD
PMID:19774075
NCBI chr X:121,373,693...121,401,923
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Sh3gl3
SH3 domain containing GRB2 like 3, endophilin A3
affects expression
EXP
Amiodarone affects the expression of SH3GL3 mRNA
CTD
PMID:18355885
NCBI chr 1:136,124,500...136,255,669
Ensembl chr 1:136,124,499...136,255,584
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Shld2
shieldin complex subunit 2
decreases expression
ISO
Amiodarone results in decreased expression of SHLD2 mRNA
CTD
PMID:24535564
NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
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Shmt2
serine hydroxymethyltransferase 2
affects expression
EXP
Amiodarone affects the expression of SHMT2 mRNA
CTD
PMID:19483382
NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
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Sipa1l3
signal-induced proliferation-associated 1 like 3
increases expression
ISO
Amiodarone results in increased expression of SIPA1L3 mRNA
CTD
PMID:19774075
NCBI chr 1:84,618,714...84,825,956
Ensembl chr 1:84,618,719...84,703,802
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Sirt4
sirtuin 4
increases expression
ISO
Amiodarone results in increased expression of SIRT4 mRNA
CTD
PMID:19774075
NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
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Siva1
SIVA1, apoptosis-inducing factor
increases expression
ISO
Amiodarone results in increased expression of SIVA1 mRNA
CTD
PMID:24535564
NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
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Six1
SIX homeobox 1
increases expression
ISO
Amiodarone results in increased expression of SIX1 mRNA
CTD
PMID:19774075
NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
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Slc10a1
solute carrier family 10 member 1
decreases expression
EXP
Amiodarone results in decreased expression of SLC10A1 mRNA
CTD
PMID:27765674
NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
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Slc13a4
solute carrier family 13 member 4
increases expression
ISO
Amiodarone results in increased expression of SLC13A4 mRNA
CTD
PMID:19774075
NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857
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Slc14a2
solute carrier family 14 member 2
increases expression
ISO
Amiodarone results in increased expression of SLC14A2 mRNA
CTD
PMID:19774075
NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
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Slc16a11
solute carrier family 16, member 11
increases expression
ISO
Amiodarone results in increased expression of SLC16A11 mRNA
CTD
PMID:24535564
NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915
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Slc16a7
solute carrier family 16 member 7
increases expression
ISO
Amiodarone results in increased expression of SLC16A7 mRNA
CTD
PMID:24535564
NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
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Slc17a2
solute carrier family 17, member 2
decreases expression
ISO
Amiodarone results in decreased expression of SLC17A2 mRNA
CTD
PMID:24535564
NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,319,701...41,336,325
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Slc1a3
solute carrier family 1 member 3
increases expression
ISO
Amiodarone results in increased expression of SLC1A3 mRNA
CTD
PMID:36586010
NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
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Slc22a1
solute carrier family 22 member 1
affects expression multiple interactions
EXP ISO
Amiodarone affects the expression of SLC22A1 mRNA Amiodarone inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
CTD
PMID:19483382 PMID:21641380
NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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Slc22a5
solute carrier family 22 member 5
multiple interactions decreases expression
ISO EXP
Amiodarone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] Amiodarone results in decreased expression of SLC22A5 mRNA
CTD
PMID:21641380 PMID:32084307
NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
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Slc23a1
solute carrier family 23 member 1
affects expression
EXP
Amiodarone affects the expression of SLC23A1 mRNA
CTD
PMID:19483382
NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
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Slc25a13
solute carrier family 25 member 13
affects expression
EXP
Amiodarone affects the expression of SLC25A13 mRNA
CTD
PMID:19483382
NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902
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Slc25a18
solute carrier family 25 member 18
increases expression
ISO
Amiodarone results in increased expression of SLC25A18 mRNA
CTD
PMID:19774075
NCBI chr 4:154,000,808...154,021,373
Ensembl chr 4:154,000,990...154,021,372
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Slc25a20
solute carrier family 25 member 20
decreases expression
EXP
Amiodarone results in decreased expression of SLC25A20 mRNA
CTD
PMID:32084307
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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Slc25a25
solute carrier family 25 member 25
increases expression
ISO
Amiodarone results in increased expression of SLC25A25 mRNA
CTD
PMID:19774075
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
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Slc25a26
solute carrier family 25 member 26
increases expression
ISO
Amiodarone results in increased expression of SLC25A26 mRNA
CTD
PMID:19774075
NCBI chr 4:127,036,704...127,131,026
Ensembl chr 4:127,036,742...127,131,020
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Slc25a3
solute carrier family 25 member 3
affects expression
EXP
Amiodarone affects the expression of SLC25A3 mRNA
CTD
PMID:19483382
NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
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Slc25a30
solute carrier family 25, member 30
increases expression
ISO
Amiodarone results in increased expression of SLC25A30 mRNA
CTD
PMID:19774075
NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
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Slc26a4
solute carrier family 26 member 4
decreases expression
ISO
Amiodarone results in decreased expression of SLC26A4 mRNA
CTD
PMID:18020914
NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
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Slc27a2
solute carrier family 27 member 2
affects expression
EXP
Amiodarone affects the expression of SLC27A2 mRNA
CTD
PMID:19483382
NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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Slc2a1
solute carrier family 2 member 1
decreases expression
ISO
Amiodarone results in decreased expression of SLC2A1 mRNA
CTD
PMID:36586010
NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc2a3
solute carrier family 2 member 3
decreases expression
ISO
Amiodarone results in decreased expression of SLC2A3 mRNA
CTD
PMID:15342952 PMID:17567588 PMID:29248575
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Slc30a1
solute carrier family 30 member 1
increases expression
ISO
Amiodarone results in increased expression of SLC30A1 mRNA
CTD
PMID:19774075
NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
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Slc35a2
solute carrier family 35 member A2
increases expression
ISO
Amiodarone results in increased expression of SLC35A2 mRNA
CTD
PMID:19774075
NCBI chr X:14,608,145...14,616,937
Ensembl chr X:14,608,055...14,616,678
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Slc38a11
solute carrier family 38, member 11
increases expression
ISO
Amiodarone results in increased expression of SLC38A11 mRNA
CTD
PMID:19774075
NCBI chr 3:49,987,119...50,033,615
Ensembl chr 3:49,987,124...50,033,615
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Slc39a8
solute carrier family 39 member 8
affects expression
EXP
Amiodarone affects the expression of SLC39A8 mRNA
CTD
PMID:19483382
NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
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Slc3a2
solute carrier family 3 member 2
increases expression
ISO
Amiodarone results in increased expression of SLC3A2 mRNA
CTD
PMID:19774075
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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Slc41a2
solute carrier family 41 member 2
decreases expression
ISO
Amiodarone results in decreased expression of SLC41A2 mRNA
CTD
PMID:24535564
NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
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Slc44a4
solute carrier family 44, member 4
decreases expression
EXP
Amiodarone results in decreased expression of SLC44A4 mRNA
CTD
PMID:17991464
NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
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Slc46a1
solute carrier family 46 member 1
affects expression
EXP
Amiodarone affects the expression of SLC46A1 mRNA
CTD
PMID:19483382
NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
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Slc4a4
solute carrier family 4 member 4
increases expression
ISO
Amiodarone results in increased expression of SLC4A4 mRNA
CTD
PMID:24535564
NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
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Slc5a3
solute carrier family 5 member 3
increases expression
ISO
Amiodarone results in increased expression of SLC5A3 mRNA
CTD
PMID:19774075
NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
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Slc5a5
solute carrier family 5 member 5
decreases expression
ISO
Amiodarone results in decreased expression of SLC5A5 mRNA
CTD
PMID:18020914
NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
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Slc66a2
solute carrier family 66 member 2
affects expression
EXP
Amiodarone affects the expression of SLC66A2 mRNA
CTD
PMID:19483382
NCBI chr18:73,702,472...73,739,678
Ensembl chr18:73,702,564...73,739,676
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Slc6a6
solute carrier family 6 member 6
affects expression
EXP
Amiodarone affects the expression of SLC6A6 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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Slc7a11
solute carrier family 7 member 11
increases expression
ISO
Amiodarone results in increased expression of SLC7A11 mRNA
CTD
PMID:36586010
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slc8a1
solute carrier family 8 member A1
increases expression
EXP
Amiodarone results in increased expression of SLC8A1 protein
CTD
PMID:7573397 PMID:12479229
NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
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Slc8a3
solute carrier family 8 member A3
decreases activity
EXP
Amiodarone results in decreased activity of SLC8A3 protein
CTD
PMID:15288574
NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508
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Slco1a4
solute carrier organic anion transporter family, member 1a4
affects expression
EXP
Amiodarone affects the expression of SLCO1A4 mRNA
CTD
PMID:18355885
NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
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Slco2b1
solute carrier organic anion transporter family, member 2b1
increases uptake
ISO
SLCO2B1 protein results in increased uptake of Amiodarone
CTD
PMID:19285480
NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
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Slco4c1
solute carrier organic anion transporter family, member 4C1
increases expression
ISO
Amiodarone results in increased expression of SLCO4C1 mRNA
CTD
PMID:19774075
NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715
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Slco5a1
solute carrier organic anion transporter family, member 5A1
increases expression
ISO
Amiodarone results in increased expression of SLCO5A1 mRNA
CTD
PMID:19774075
NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913
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Slfn5
schlafen family member 5
increases expression
ISO
Amiodarone results in increased expression of SLFN5 mRNA
CTD
PMID:19774075
NCBI chr10:67,881,068...67,895,013
Ensembl chr10:67,880,009...67,893,109
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Slitrk3
SLIT and NTRK-like family, member 3
increases expression
ISO
Amiodarone results in increased expression of SLITRK3 mRNA
CTD
PMID:19774075
NCBI chr 2:157,680,067...157,697,404
Ensembl chr 2:157,687,535...157,696,709
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Slx4ip
SLX4 interacting protein
increases expression
ISO
Amiodarone results in increased expression of SLX4IP mRNA
CTD
PMID:19774075
NCBI chr 3:124,220,215...124,396,797
Ensembl chr 3:124,221,198...124,396,797
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Smg6
SMG6 nonsense mediated mRNA decay factor
increases expression
ISO
Amiodarone results in increased expression of SMG6 mRNA
CTD
PMID:19774075
NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395
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Smim11
small integral membrane protein 11
increases expression
ISO
Amiodarone results in increased expression of SMIM11 mRNA
CTD
PMID:19774075
NCBI chr11:31,533,257...31,543,002
Ensembl chr11:31,532,764...31,543,002
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Smox
spermine oxidase
increases expression
ISO
Amiodarone results in increased expression of SMOX mRNA
CTD
PMID:19774075
NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
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Snai1
snail family transcriptional repressor 1
decreases expression multiple interactions
ISO
Amiodarone results in decreased expression of SNAI1 protein Amiodarone affects the reaction [VCAN protein alternative form affects the expression of SNAI1 protein]; MAP2K1 protein inhibits the reaction [Amiodarone results in decreased expression of SNAI1 protein]
CTD
PMID:26515726
NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
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Snrnp35
small nuclear ribonucleoprotein U11/U12 subunit 35
increases expression
ISO
Amiodarone results in increased expression of SNRNP35 mRNA
CTD
PMID:19774075
NCBI chr12:32,112,032...32,119,829
Ensembl chr12:32,110,993...32,122,660
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Snx18
sorting nexin 18
increases expression
ISO
Amiodarone results in increased expression of SNX18 mRNA
CTD
PMID:19774075
NCBI chr 2:45,232,325...45,258,345
Ensembl chr 2:45,232,325...45,258,345
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Socs6
suppressor of cytokine signaling 6
increases expression
ISO
Amiodarone results in increased expression of SOCS6 mRNA
CTD
PMID:19774075
NCBI chr18:82,111,866...82,139,193
Ensembl chr18:82,111,827...82,139,219
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Sod1
superoxide dismutase 1
decreases expression multiple interactions
ISO
Amiodarone results in decreased expression of SOD1 mRNA ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]]
CTD
PMID:34434487
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
increases expression multiple interactions decreases expression
ISO
Amiodarone results in increased expression of SOD2 mRNA; Amiodarone results in increased expression of SOD2 protein ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]]
CTD
PMID:23135547 PMID:28526448 PMID:34434487
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Spag1
sperm associated antigen 1
increases expression
ISO
Amiodarone results in increased expression of SPAG1 mRNA
CTD
PMID:19774075
NCBI chr 7:67,361,474...67,421,369
Ensembl chr 7:67,361,477...67,421,368
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Spata17
spermatogenesis associated 17
increases expression
ISO
Amiodarone results in increased expression of SPATA17 mRNA
CTD
PMID:19774075
NCBI chr13:98,605,986...98,784,855
Ensembl chr13:98,605,986...98,784,929
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Spata2L
spermatogenesis associated 2-like
increases expression
ISO
Amiodarone results in increased expression of SPATA2L mRNA
CTD
PMID:19774075
NCBI chr19:51,269,078...51,273,605
Ensembl chr19:51,269,078...51,273,510
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Spc24
SPC24 component of NDC80 kinetochore complex
increases expression
ISO
Amiodarone results in increased expression of SPC24 mRNA
CTD
PMID:24535564
NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310
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Spef2
sperm flagellar 2
increases expression
ISO
Amiodarone results in increased expression of SPEF2 mRNA
CTD
PMID:19774075
NCBI chr 2:58,512,489...58,694,718
Ensembl chr 2:58,512,489...58,694,664
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Spmip4
sperm microtubule inner protein 4
increases expression
ISO
Amiodarone results in increased expression of SPMIP4 mRNA
CTD
PMID:19774075
NCBI chr 4:79,663,375...79,688,291
Ensembl chr 4:79,663,376...79,689,072
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Spopl
speckle type BTB/POZ protein like
increases expression
ISO
Amiodarone results in increased expression of SPOPL mRNA
CTD
PMID:19774075
NCBI chr 3:6,074,681...6,148,508
Ensembl chr 3:6,078,310...6,108,794
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Sppl2a
signal peptide peptidase-like 2A
affects expression
EXP
Amiodarone affects the expression of SPPL2A mRNA
CTD
PMID:19483382
NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:114,151,069...114,193,264
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Spr
sepiapterin reductase
increases expression
ISO
Amiodarone results in increased expression of SPR mRNA
CTD
PMID:19774075
NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
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Sptbn1
spectrin, beta, non-erythrocytic 1
increases expression
ISO
Amiodarone results in increased expression of SPTBN1 mRNA
CTD
PMID:19774075
NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
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Sqle
squalene epoxidase
increases expression
ISO
Amiodarone results in increased expression of SQLE mRNA
CTD
PMID:24489787
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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Sqstm1
sequestosome 1
increases expression affects expression decreases expression
ISO
Amiodarone results in increased expression of SQSTM1 mRNA Amiodarone affects the expression of SQSTM1 mRNA Amiodarone results in decreased expression of SQSTM1 protein
CTD
PMID:19774075 PMID:32651653 PMID:36586010
NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srebf1
sterol regulatory element binding transcription factor 1
decreases expression increases expression
EXP ISO
Amiodarone results in decreased expression of SREBF1 mRNA Amiodarone results in increased expression of SREBF1 mRNA
CTD
PMID:17202758 PMID:28962527 PMID:32651653 PMID:34259586
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Srek1ip1
SREK1-interacting protein 1
increases expression
ISO
Amiodarone results in increased expression of SREK1IP1 mRNA
CTD
PMID:19774075
NCBI chr 2:35,975,978...35,999,636
Ensembl chr 2:35,975,989...35,999,636
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Srm
spermidine synthase
affects expression
EXP
Amiodarone affects the expression of SRM mRNA
CTD
PMID:19483382
NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
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Srprb
SRP receptor subunit beta
affects expression
EXP
Amiodarone affects the expression of SRPRB mRNA
CTD
PMID:19483382
NCBI chr 8:103,768,685...103,782,632
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Ss18l1
SS18L1 subunit of BAF chromatin remodeling complex
increases expression
ISO
Amiodarone results in increased expression of SS18L1 mRNA
CTD
PMID:19774075
NCBI chr 3:167,143,730...167,165,253
Ensembl chr 3:167,143,994...167,165,253
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Ssx2ip
SSX family member 2 interacting protein
affects expression
EXP
Amiodarone affects the expression of SSX2IP mRNA
CTD
PMID:19483382
NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
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St13
ST13, Hsp70 interacting protein
affects expression
EXP
Amiodarone affects the expression of ST13 mRNA
CTD
PMID:18355885
NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945
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St3gal6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
affects expression
EXP
Amiodarone affects the expression of ST3GAL6 mRNA
CTD
PMID:19483382
NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
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St6gal1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
affects expression
EXP
Amiodarone affects the expression of ST6GAL1 mRNA
CTD
PMID:19483382
NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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Stard5
StAR-related lipid transfer domain containing 5
increases expression
ISO
Amiodarone results in increased expression of STARD5 mRNA
CTD
PMID:19774075
NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469
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Stat1
signal transducer and activator of transcription 1
decreases expression
ISO
Amiodarone results in decreased expression of STAT1 mRNA
CTD
PMID:35641671
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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Stat2
signal transducer and activator of transcription 2
decreases expression
ISO
Amiodarone results in decreased expression of STAT2 mRNA
CTD
PMID:35641671
NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
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Stbd1
starch binding domain 1
affects expression
EXP
Amiodarone affects the expression of STBD1 mRNA
CTD
PMID:18355885
NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
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Stk16
serine/threonine kinase 16
increases expression
ISO
Amiodarone results in increased expression of STK16 mRNA
CTD
PMID:19774075
NCBI chr 9:76,705,591...76,708,859
Ensembl chr 9:76,705,602...76,708,855
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Stmn1
stathmin 1
affects expression
EXP
Amiodarone affects the expression of STMN1 mRNA
CTD
PMID:18355885
NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
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Stum
stum, mechanosensory transduction mediator homolog
increases expression
ISO
Amiodarone results in increased expression of STUM mRNA
CTD
PMID:19774075
NCBI chr13:92,172,175...92,227,205
Ensembl chr13:92,173,544...92,227,213
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Stx11
syntaxin 11
increases expression
ISO
Amiodarone results in increased expression of STX11 mRNA
CTD
PMID:19774075
NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
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Stxbp2
syntaxin binding protein 2
increases expression
ISO
Amiodarone results in increased expression of STXBP2 mRNA
CTD
PMID:19774075
NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
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Suclg1
succinate-CoA ligase GDP/ADP-forming subunit alpha
affects expression increases expression
EXP ISO
Amiodarone affects the expression of SUCLG1 mRNA Amiodarone results in increased expression of SUCLG1 mRNA
CTD
PMID:19483382 PMID:24489787
NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600
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Sulf2
sulfatase 2
increases expression
ISO
Amiodarone results in increased expression of SULF2 mRNA
CTD
PMID:24535564
NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
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Sult2a1
sulfotransferase family 2A member 1
increases expression
ISO
Amiodarone results in increased expression of SULT2A1 protein
CTD
PMID:23308384
NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
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Surf4
surfeit 4
affects expression
EXP
Amiodarone affects the expression of SURF4 mRNA
CTD
PMID:19483382
NCBI chr 3:10,248,360...10,261,537
Ensembl chr 3:10,241,837...10,263,315
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Svil
supervillin
increases expression
ISO
Amiodarone results in increased expression of SVIL mRNA
CTD
PMID:19774075
NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
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Synj2bp
synaptojanin 2 binding protein
affects expression
EXP
Amiodarone affects the expression of SYNJ2BP mRNA
CTD
PMID:19483382
NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
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Taf5l1
TATA-box binding protein associated factor 5 like 1
increases expression
ISO
Amiodarone results in increased expression of TAF5L mRNA
CTD
PMID:19774075
NCBI chr19:51,991,704...52,011,001
Ensembl chr19:51,991,708...52,011,295
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Tafazzin
tafazzin, phospholipid-lysophospholipid transacylase
increases expression
ISO
Amiodarone results in increased expression of TAFAZZIN mRNA
CTD
PMID:19774075 PMID:24489787
NCBI chr X:152,065,539...152,076,178
Ensembl chr X:152,065,609...152,074,001
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Tagln
transgelin
decreases expression
ISO
Amiodarone results in decreased expression of TAGLN mRNA
CTD
PMID:17175557 PMID:17567588
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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Tapbpl
TAP binding protein-like
increases expression
ISO
Amiodarone results in increased expression of TAPBPL mRNA
CTD
PMID:19774075
NCBI chr 4:158,021,454...158,028,905
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Tas2r106
taste receptor, type 2, member 106
increases expression
ISO
Amiodarone results in increased expression of TAS2R10 mRNA
CTD
PMID:19774075
NCBI chr 4:165,313,210...165,314,133
Ensembl chr 4:165,313,210...165,314,133
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Tbx3
T-box transcription factor 3
increases expression
ISO
Amiodarone results in increased expression of TBX3 mRNA
CTD
PMID:23397585
NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
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Tbx4
T-box transcription factor 4
increases expression
ISO
Amiodarone results in increased expression of TBX4 mRNA
CTD
PMID:19774075
NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825
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Tbxas1
thromboxane A synthase 1
increases expression
EXP
Amiodarone results in increased expression of TBXAS1 mRNA
CTD
PMID:22291062
NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
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Tcaim
T cell activation inhibitor, mitochondrial
increases expression
ISO
Amiodarone results in increased expression of TCAIM mRNA
CTD
PMID:19774075
NCBI chr 8:122,414,827...122,446,105
Ensembl chr 8:122,414,818...122,446,092
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Tcf20
transcription factor 20
increases expression
ISO
Amiodarone results in increased expression of TCF20 mRNA
CTD
PMID:19774075
NCBI chr 7:113,953,449...114,104,166
Ensembl chr 7:113,954,089...114,051,839
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Tcf7
transcription factor 7
increases expression
ISO
Amiodarone results in increased expression of TCF7 mRNA
CTD
PMID:19774075
NCBI chr10:36,423,443...36,454,350
Ensembl chr10:36,423,445...36,453,535
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Tdo2
tryptophan 2,3-dioxygenase
increases expression
ISO
Amiodarone results in increased expression of TDO2 mRNA
CTD
PMID:19774075
NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
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Tef
TEF transcription factor, PAR bZIP family member
increases expression
ISO
Amiodarone results in increased expression of TEF mRNA
CTD
PMID:19774075
NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
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Tenm3
teneurin transmembrane protein 3
increases expression
ISO
Amiodarone results in increased expression of TENM3 mRNA
CTD
PMID:24535564
NCBI chr16:41,251,909...43,978,594
Ensembl chr16:41,252,182...43,978,594
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Terf1
telomeric repeat binding factor 1
increases expression
ISO
Amiodarone results in increased expression of TERF1 mRNA
CTD
PMID:19774075
NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
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Tex261
testis expressed 261
affects expression
EXP
Amiodarone affects the expression of TEX261 mRNA
CTD
PMID:18355885
NCBI chr 4:116,253,547...116,260,730
Ensembl chr 4:116,244,600...116,260,253
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Tf
transferrin
decreases expression increases expression
EXP ISO
Amiodarone results in decreased expression of TF protein Amiodarone results in increased expression of TF mRNA
CTD
PMID:16538043 PMID:36586010
NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
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Tfap2c
transcription factor AP-2 gamma
increases expression
ISO
Amiodarone results in increased expression of TFAP2C mRNA
CTD
PMID:19774075
NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
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Tfb1m
transcription factor B1, mitochondrial
increases expression
ISO
Amiodarone results in increased expression of TFB1M mRNA
CTD
PMID:24489787
NCBI chr 1:44,115,240...44,161,737
Ensembl chr 1:44,119,166...44,161,709
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Tfeb
transcription factor EB
multiple interactions affects localization
ISO
TFEB protein inhibits the reaction [Amiodarone results in increased import of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine] Amiodarone affects the localization of TFEB protein
CTD
PMID:25881747
NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
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Tff3
trefoil factor 3
decreases expression
ISO
Amiodarone results in decreased expression of TFF3 mRNA
CTD
PMID:24535564
NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
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Tfg
trafficking from ER to golgi regulator
increases expression
ISO
Amiodarone results in increased expression of TFG mRNA
CTD
PMID:19774075
NCBI chr11:43,885,542...43,911,976
Ensembl chr11:43,885,661...43,911,976
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Tg
thyroglobulin
decreases expression increases expression multiple interactions
ISO EXP
Amiodarone results in decreased expression of TG mRNA; Amiodarone results in decreased expression of TG protein Amiodarone results in increased expression of TG mRNA 4-phenylbutyric acid inhibits the reaction [Amiodarone results in decreased expression of TG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Amiodarone results in decreased expression of TG protein]
CTD
PMID:18020914 PMID:25295624 PMID:27197836
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
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Tgfb1
transforming growth factor, beta 1
increases expression multiple interactions
EXP
Amiodarone results in increased expression of TGFB1 mRNA; Amiodarone results in increased expression of TGFB1 protein [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein]
CTD
PMID:11597910 PMID:34590760
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbi
transforming growth factor, beta induced
affects expression
EXP
Amiodarone affects the expression of TGFBI mRNA
CTD
PMID:19483382
NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
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Tgoln2
trans-golgi network protein 2
increases expression
ISO
Amiodarone results in increased expression of TGOLN2 mRNA
CTD
PMID:23397585
NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
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Thnsl2
threonine synthase-like 2
affects expression
EXP
Amiodarone affects the expression of THNSL2 mRNA
CTD
PMID:19483382
NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
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Thra
thyroid hormone receptor alpha
affects binding decreases expression increases activity multiple interactions increases expression
ISO EXP
Amiodarone binds to THRA protein Amiodarone results in decreased expression of THRA mRNA alternative form Amiodarone results in increased activity of THRA protein [Isoproterenol co-treated with Amiodarone] results in increased expression of THRA mRNA alternative form Amiodarone results in increased expression of THRA mRNA alternative form
CTD
PMID:7598731 PMID:10445678 PMID:11806713 PMID:17535870 PMID:22015988
NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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Thrb
thyroid hormone receptor beta
affects binding multiple interactions decreases expression increases expression
ISO EXP
Amiodarone binds to THRB protein Amiodarone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein] Amiodarone results in decreased expression of THRB mRNA alternative form [Isoproterenol co-treated with Amiodarone] results in increased expression of THRB mRNA alternative form; Amiodarone inhibits the reaction [Isoproterenol results in increased expression of THRB mRNA alternative form] Amiodarone results in increased expression of THRB mRNA
CTD
PMID:7598731 PMID:10445678 PMID:11806713 PMID:17535870 PMID:19774075 PMID:31077750 More...
NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
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Thrsp
thyroid hormone responsive
increases expression multiple interactions
EXP
Amiodarone results in increased expression of THRSP mRNA Triiodothyronine inhibits the reaction [Amiodarone results in increased expression of THRSP mRNA]
CTD
PMID:2721112 PMID:17991464
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Timm10b
translocase of inner mitochondrial membrane 10B
affects expression
EXP
Amiodarone affects the expression of TIMM10B mRNA
CTD
PMID:18355885
NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
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Timm13
translocase of inner mitochondrial membrane 13
increases expression
ISO
Amiodarone results in increased expression of TIMM13 mRNA
CTD
PMID:19774075
NCBI chr 7:8,809,069...8,810,172
Ensembl chr 7:8,809,058...8,809,910
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Timm17a
translocase of inner mitochondrial membrane 17A
increases expression
ISO
Amiodarone results in increased expression of TIMM17A mRNA
CTD
PMID:19774075
NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
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Timm21
translocase of inner mitochondrial membrane 21
affects expression
EXP
Amiodarone affects the expression of TIMM21 mRNA
CTD
PMID:19483382
NCBI chr18:78,314,900...78,319,362
Ensembl chr18:78,314,909...78,319,454
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Tinag
tubulointerstitial nephritis antigen
increases expression
ISO
Amiodarone results in increased expression of TINAG mRNA
CTD
PMID:19774075
NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
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Tjp3
tight junction protein 3
decreases expression
EXP
Amiodarone results in decreased expression of TJP3 mRNA
CTD
PMID:17991464
NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
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Tkfc
triokinase and FMN cyclase
affects expression
EXP
Amiodarone affects the expression of TKFC mRNA
CTD
PMID:19483382
NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
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Tktl1
transketolase-like 1
increases expression
ISO
Amiodarone results in increased expression of TKTL1 mRNA
CTD
PMID:19774075
NCBI chr X:151,954,261...151,987,208
Ensembl chr X:151,954,175...151,987,208
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Tlcd1
TLC domain containing 1
decreases expression
EXP
Amiodarone results in decreased expression of TLCD1 mRNA
CTD
PMID:17991464
NCBI chr10:63,074,469...63,076,502
Ensembl chr10:63,074,469...63,076,501
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Tm7sf2
transmembrane 7 superfamily member 2
increases expression
EXP
Amiodarone results in increased expression of TM7SF2 mRNA
CTD
PMID:22291062
NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
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Tmbim1
transmembrane BAX inhibitor motif containing 1
affects expression
EXP
Amiodarone affects the expression of TMBIM1 mRNA
CTD
PMID:19483382
NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
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Tmcc2
transmembrane and coiled-coil domain family 2
increases expression
ISO
Amiodarone results in increased expression of TMCC2 mRNA
CTD
PMID:19774075
NCBI chr13:43,794,029...43,831,716
Ensembl chr13:43,794,029...43,831,716
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Tmco1
transmembrane and coiled-coil domains 1
affects expression
EXP
Amiodarone affects the expression of TMCO1 mRNA
CTD
PMID:19483382
NCBI chr13:79,460,229...79,483,557
Ensembl chr13:79,460,135...79,483,555
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Tmed2
transmembrane p24 trafficking protein 2
affects expression
EXP
Amiodarone affects the expression of TMED2 mRNA
CTD
PMID:19483382
NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
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Tmed7
transmembrane p24 trafficking protein 7
affects expression
EXP
Amiodarone affects the expression of TMED7 mRNA
CTD
PMID:19483382
NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
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Tmem123
transmembrane protein 123
affects expression
EXP
Amiodarone affects the expression of TMEM123 mRNA
CTD
PMID:19483382
NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224
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Tmem161b
transmembrane protein 161B
increases expression
ISO
Amiodarone results in increased expression of TMEM161B mRNA
CTD
PMID:19774075
NCBI chr 2:14,714,451...14,793,809
Ensembl chr 2:14,715,701...14,793,803
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Tmem68
transmembrane protein 68
increases expression
ISO
Amiodarone results in increased expression of TMEM68 mRNA
CTD
PMID:19774075
NCBI chr 5:16,494,054...16,524,842
Ensembl chr 5:16,494,276...16,524,569
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Tmem97
transmembrane protein 97
affects expression
EXP
Amiodarone affects the expression of TMEM97 mRNA
CTD
PMID:19483382
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
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Tmem98
transmembrane protein 98
increases expression
ISO
Amiodarone results in increased expression of TMEM98 mRNA
CTD
PMID:24535564
NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
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Tmlhe
trimethyllysine hydroxylase, epsilon
increases expression
ISO
Amiodarone results in increased expression of TMLHE mRNA
CTD
PMID:19774075
NCBI chr20:91,234...138,942
Ensembl chr20:91,272...140,386
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Tmprss9
transmembrane serine protease 9
increases expression
ISO
Amiodarone results in increased expression of TMPRSS9 mRNA
CTD
PMID:19774075
NCBI chr 7:8,810,321...8,831,177
Ensembl chr 7:8,810,320...8,831,177
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Tmtc2
transmembrane O-mannosyltransferase targeting cadherins 2
increases expression
ISO
Amiodarone results in increased expression of TMTC2 mRNA
CTD
PMID:24535564
NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:40,394,220...40,807,298
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Tmub2
transmembrane and ubiquitin-like domain containing 2
increases expression
ISO
Amiodarone results in increased expression of TMUB2 mRNA
CTD
PMID:19774075
NCBI chr10:87,238,543...87,242,968
Ensembl chr10:87,238,548...87,242,779
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Tnf
tumor necrosis factor
multiple interactions increases expression
ISO EXP
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of TNF protein; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Amiodarone inhibits the reaction [CRP protein results in increased expression of TNF protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein] Amiodarone results in increased expression of TNF mRNA; Amiodarone results in increased expression of TNF protein [Amiodarone co-treated with TNF protein] results in increased activity of CASP9 protein [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of TNF protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of TNF protein]; Olmesartan Medoxomil inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of TNF protein]; TNF protein affects the susceptibility to [Amiodarone co-treated with Lipopolysaccharides]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of TNF protein]
CTD
PMID:18974383 PMID:19225199 PMID:19362101 PMID:21984482 PMID:22785256 PMID:23042730 PMID:23305835 PMID:25073960 PMID:26781185 PMID:34259586 PMID:34434487 PMID:34590760 More...
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip3
TNF alpha induced protein 3
increases expression
ISO
Amiodarone results in increased expression of TNFAIP3 mRNA
CTD
PMID:19774075
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tnfsf10
TNF superfamily member 10
increases response to substance multiple interactions
ISO
Amiodarone results in increased susceptibility to TNFSF10 protein [TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP3 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP9 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of PARP1 protein
CTD
PMID:21292685
NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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Tnnt1
troponin T1, slow skeletal type
increases expression
ISO
Amiodarone results in increased expression of TNNT1 mRNA
CTD
PMID:19774075
NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
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Tnrc6a
trinucleotide repeat containing adaptor 6A
increases expression
ISO
Amiodarone results in increased expression of TNRC6A mRNA
CTD
PMID:19774075
NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
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Tom1l1
target of myb1 like 1 membrane trafficking protein
increases expression
ISO
Amiodarone results in increased expression of TOM1L1 mRNA
CTD
PMID:19774075
NCBI chr10:75,464,577...75,508,304
Ensembl chr10:75,464,577...75,508,250
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Top1mt
DNA topoisomerase I mitochondrial
increases expression
ISO
Amiodarone results in increased expression of TOP1MT mRNA
CTD
PMID:24489787
NCBI chr 7:107,338,092...107,368,125
Ensembl chr 7:107,342,527...107,366,049
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Tp53
tumor protein p53
decreases expression
ISO
Amiodarone results in decreased expression of TP53 mRNA
CTD
PMID:35641671
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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Tpo
thyroid peroxidase
decreases expression increases expression
ISO EXP
Amiodarone results in decreased expression of TPO mRNA Amiodarone results in increased expression of TPO mRNA
CTD
PMID:18020914 PMID:27197836
NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
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Tpst1
tyrosylprotein sulfotransferase 1
decreases expression
ISO
Amiodarone results in decreased expression of TPST1 mRNA
CTD
PMID:24535564
NCBI chr12:26,544,536...26,605,706
Ensembl chr12:26,544,536...26,605,704
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Trex1
three prime repair exonuclease 1
increases expression
ISO
Amiodarone results in increased expression of TREX1 mRNA
CTD
PMID:19774075
NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
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Trib3
tribbles pseudokinase 3
increases expression
ISO
Amiodarone results in increased expression of TRIB3 mRNA
CTD
PMID:19774075 PMID:24535564 PMID:36586010
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Trim36
tripartite motif-containing 36
increases expression
ISO
Amiodarone results in increased expression of TRIM36 mRNA
CTD
PMID:19774075
NCBI chr18:38,859,604...38,912,859
Ensembl chr18:38,861,018...38,912,859
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Trmt10b
tRNA methyltransferase 10B
increases expression
ISO
Amiodarone results in increased expression of TRMT10B mRNA
CTD
PMID:19774075
NCBI chr 5:59,548,845...59,572,529
Ensembl chr 5:59,548,869...59,572,526
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Trmu
tRNA mitochondrial 2-thiouridylase
increases expression
ISO
Amiodarone results in increased expression of TRMU mRNA
CTD
PMID:24489787
NCBI chr 7:116,969,750...116,987,704
Ensembl chr 7:116,969,756...116,986,355
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Trnt1
tRNA nucleotidyl transferase 1
increases expression
ISO
Amiodarone results in increased expression of TRNT1 mRNA
CTD
PMID:19774075
NCBI chr 4:139,681,115...139,703,611
Ensembl chr 4:139,680,858...139,703,611
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Trpv2
transient receptor potential cation channel, subfamily V, member 2
increases expression
ISO
Amiodarone results in increased expression of TRPV2 mRNA
CTD
PMID:19774075
NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
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Tsga10
testis specific 10
increases expression
ISO
Amiodarone results in increased expression of TSGA10 mRNA
CTD
PMID:19774075
NCBI chr 9:39,991,203...40,098,259
Ensembl chr 9:39,991,830...40,098,232
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Tshb
thyroid stimulating hormone subunit beta
increases expression
ISO EXP
Amiodarone results in increased expression of TSHB protein Amiodarone results in increased expression of TSHB mRNA; Amiodarone results in increased expression of TSHB protein
CTD
PMID:1860199 PMID:3427795 PMID:12538616
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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Tslp
thymic stromal lymphopoietin
increases expression
ISO
Amiodarone results in increased expression of TSLP mRNA
CTD
PMID:19774075
NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
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Tspyl2
TSPY-like 2
increases expression
ISO
Amiodarone results in increased expression of TSPYL2 mRNA
CTD
PMID:19774075
NCBI chr X:21,439,478...21,445,208
Ensembl chr X:21,439,478...21,445,089
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Ttbk2
tau tubulin kinase 2
increases expression
ISO
Amiodarone results in increased expression of TTBK2 mRNA
CTD
PMID:19774075
NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223
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Ttll3
tubulin tyrosine ligase like 3
increases expression
ISO
Amiodarone results in increased expression of TTLL3 mRNA
CTD
PMID:19774075
NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889
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Tuba1a
tubulin, alpha 1A
decreases expression
ISO
Amiodarone results in decreased expression of TUBA1A mRNA
CTD
PMID:27015953
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
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Tusc3
tumor suppressor candidate 3
increases expression
ISO
Amiodarone results in increased expression of TUSC3 mRNA
CTD
PMID:19774075
NCBI chr16:53,196,195...53,345,241
Ensembl chr16:53,196,195...53,344,781
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Txn1
thioredoxin 1
affects expression
EXP
Amiodarone affects the expression of TXN1 mRNA
CTD
PMID:19483382
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnl1
thioredoxin-like 1
affects expression
EXP
Amiodarone affects the expression of TXNL1 mRNA
CTD
PMID:19483382
NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
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Uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
affects expression
EXP
Amiodarone affects the expression of UBA52 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
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Ube2d2
ubiquitin-conjugating enzyme E2D 2
increases expression
ISO
Amiodarone results in increased expression of UBE2D2 mRNA
CTD
PMID:19774075
NCBI chr18:27,364,325...27,406,322
Ensembl chr18:27,364,303...27,406,181
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Ube2d3
ubiquitin-conjugating enzyme E2D 3
increases expression
ISO
Amiodarone results in increased expression of UBE2D3 mRNA
CTD
PMID:19774075
NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
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Ube2n
ubiquitin-conjugating enzyme E2N
affects expression
EXP
Amiodarone affects the expression of UBE2N mRNA
CTD
PMID:19483382
NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
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Ubxn10
UBX domain protein 10
increases expression
ISO
Amiodarone results in increased expression of UBXN10 mRNA
CTD
PMID:19774075
NCBI chr 5:150,953,772...150,959,608
Ensembl chr 5:150,950,731...150,959,744
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Ubxn11
UBX domain protein 11
increases expression
ISO
Amiodarone results in increased expression of UBXN11 mRNA
CTD
PMID:19774075
NCBI chr 5:146,329,666...146,353,529
Ensembl chr 5:146,329,842...146,353,526
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Ufd1
ubiquitin recognition factor in ER associated degradation 1
affects expression
EXP
Amiodarone affects the expression of UFD1 mRNA
CTD
PMID:19483382
NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
affects expression
EXP
Amiodarone affects the expression of UGT1A1 mRNA
CTD
PMID:18355885 PMID:19483382
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ugt2a1
UDP glucuronosyltransferase family 2 member A1
affects expression
EXP
Amiodarone affects the expression of UGT2A1 mRNA
CTD
PMID:18355885
NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531
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Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
affects expression
EXP
Amiodarone affects the expression of UGT2B1 mRNA
CTD
PMID:18355885
NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
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Ulk3
unc-51 like kinase 3
increases expression
ISO
Amiodarone results in increased expression of ULK3 mRNA
CTD
PMID:19774075
NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467
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Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
affects expression
EXP
Amiodarone affects the expression of UQCR11 mRNA
CTD
PMID:19483382
NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750
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Usf1
upstream transcription factor 1
increases expression
ISO
Amiodarone results in increased expression of USF1 mRNA
CTD
PMID:19774075
NCBI chr13:83,845,230...83,854,875
Ensembl chr13:83,822,035...83,854,885
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Usp2
ubiquitin specific peptidase 2
increases expression
ISO
Amiodarone results in increased expression of USP2 mRNA
CTD
PMID:19774075
NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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Usp25
ubiquitin specific peptidase 25
increases expression
ISO
Amiodarone results in increased expression of USP25 mRNA
CTD
PMID:19774075
NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348
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Uts2
urotensin 2
increases expression
ISO
Amiodarone results in increased expression of UTS2 mRNA
CTD
PMID:19774075
NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
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Vcam1
vascular cell adhesion molecule 1
increases expression
ISO
Amiodarone results in increased expression of VCAM1 mRNA
CTD
PMID:19774075
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vcan
versican
affects expression multiple interactions
ISO
Amiodarone affects the expression of VCAN protein alternative form Amiodarone affects the reaction [VCAN protein alternative form affects the expression of SNAI1 protein]; Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein]
CTD
PMID:26515726
NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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Vdac2
voltage-dependent anion channel 2
increases expression
ISO
Amiodarone results in increased expression of VDAC2 mRNA
CTD
PMID:24489787
NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
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Vegfa
vascular endothelial growth factor A
increases expression
ISO
Amiodarone results in increased expression of VEGFA mRNA
CTD
PMID:19774075
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vim
vimentin
multiple interactions increases expression
ISO
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of VIM mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of VIM protein]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of VIM mRNA]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of VIM protein]
CTD
PMID:31071512
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Vldlr
very low density lipoprotein receptor
decreases expression
ISO
Amiodarone results in decreased expression of VLDLR mRNA
CTD
PMID:28962527
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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Vmac
vimentin-type intermediate filament associated coiled-coil protein
increases expression
ISO
Amiodarone results in increased expression of VMAC mRNA
CTD
PMID:19774075
NCBI chr 9:1,546,747...1,550,417
Ensembl chr 9:1,546,747...1,549,771
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Vnn1
vanin 1
affects expression increases expression
EXP ISO
Amiodarone affects the expression of VNN1 mRNA Amiodarone results in increased expression of VNN1 mRNA
CTD
PMID:19483382 PMID:24535564
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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Vps11
VPS11 core subunit of CORVET and HOPS complexes
increases expression
ISO
Amiodarone results in increased expression of VPS11 mRNA
CTD
PMID:19774075
NCBI chr 8:44,684,129...44,698,568
Ensembl chr 8:44,684,127...44,698,568
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Vps13b
vacuolar protein sorting 13 homolog B
increases expression
ISO
Amiodarone results in increased expression of VPS13B mRNA
CTD
PMID:19774075
NCBI chr 7:66,557,862...67,128,429
Ensembl chr 7:66,558,471...67,128,429
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Vps16
VPS16 core subunit of CORVET and HOPS complexes
increases expression
ISO
Amiodarone results in increased expression of VPS16 mRNA
CTD
PMID:19774075
NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441
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Vwa1
von Willebrand factor A domain containing 1
decreases expression
EXP
Amiodarone results in decreased expression of VWA1 mRNA
CTD
PMID:17991464
NCBI chr 5:166,377,451...166,382,784
Ensembl chr 5:166,377,455...166,382,637
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Wdr26
WD repeat domain 26
affects expression
EXP
Amiodarone affects the expression of WDR26 mRNA
CTD
PMID:19483382
NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
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Wipi1
WD repeat domain, phosphoinositide interacting 1
increases expression
ISO
Amiodarone results in increased expression of WIPI1 mRNA
CTD
PMID:15342952 PMID:17567588
NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
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Wnk1
WNK lysine deficient protein kinase 1
increases expression
ISO
Amiodarone results in increased expression of WNK1 mRNA
CTD
PMID:19774075
NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
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Wtap
WT1 associated protein
increases expression
ISO
Amiodarone results in increased expression of WTAP mRNA
CTD
PMID:19774075
NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065
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Xbp1
X-box binding protein 1
increases expression increases splicing multiple interactions decreases expression affects localization
ISO
Amiodarone results in increased expression of XBP1 mRNA Amiodarone results in increased splicing of XBP1 mRNA 4-phenylbutyric acid inhibits the reaction [[Amiodarone results in increased splicing of XBP1 mRNA] which results in increased expression of XBP1 mRNA alternative form]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of XBP1 mRNA]; [Amiodarone results in increased splicing of XBP1 mRNA] which results in increased expression of XBP1 mRNA alternative form Amiodarone results in decreased expression of XBP1 mRNA 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA] Amiodarone affects the localization of XBP1 protein
CTD
PMID:19774075 PMID:25295624 PMID:28962527 PMID:35641671 PMID:36586010
NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Xk
X-linked Kx blood group antigen, Kell and VPS13A binding protein
increases expression
ISO
Amiodarone results in increased expression of XK mRNA
CTD
PMID:19774075
NCBI chr X:13,436,412...13,472,830
Ensembl chr X:13,436,418...13,472,830
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Xpnpep2
X-prolyl aminopeptidase 2
increases expression
ISO
Amiodarone results in increased expression of XPNPEP2 mRNA
CTD
PMID:19774075
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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Xpo7
exportin 7
decreases expression
EXP
Amiodarone results in decreased expression of XPO7 mRNA
CTD
PMID:17991464
NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050
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Xrcc5
X-ray repair cross complementing 5
increases expression
ISO
Amiodarone results in increased expression of XRCC5 mRNA
CTD
PMID:24489787
NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
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Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
affects expression
EXP
Amiodarone affects the expression of YWHAG mRNA
CTD
PMID:19483382
NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
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Zbed3
zinc finger, BED-type containing 3
increases expression
ISO
Amiodarone results in increased expression of ZBED3 mRNA
CTD
PMID:19774075
NCBI chr 2:26,587,620...26,600,177
Ensembl chr 2:26,587,572...26,600,386
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Zbtb49
zinc finger and BTB domain containing 49
increases expression
ISO
Amiodarone results in increased expression of ZBTB49 mRNA
CTD
PMID:19774075
NCBI chr14:72,590,692...72,612,404
Ensembl chr14:72,590,708...72,612,404
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Zc3hav1
zinc finger CCCH-type containing, antiviral 1
increases expression
ISO
Amiodarone results in increased expression of ZC3HAV1 mRNA
CTD
PMID:19774075
NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428
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Zdhhc15
zinc finger DHHC-type palmitoyltransferase 15
increases expression
ISO
Amiodarone results in increased expression of ZDHHC15 mRNA
CTD
PMID:19774075
NCBI chr X:69,568,086...69,701,756
Ensembl chr X:69,574,124...69,701,756
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Zdhhc23
zinc finger DHHC-type palmitoyltransferase 23
affects expression
EXP
Amiodarone affects the expression of ZDHHC23 mRNA
CTD
PMID:19483382
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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Zfp13
zinc finger protein 13
increases expression
ISO
Amiodarone results in increased expression of ZNF205 mRNA
CTD
PMID:19774075
NCBI chr10:12,615,455...12,623,615
Ensembl chr10:12,615,190...12,623,615
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Zfp36
zinc finger protein 36
increases expression
ISO
Amiodarone results in increased expression of ZFP36 mRNA
CTD
PMID:19774075
NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
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Zfp420
zinc finger protein 420
increases expression
ISO
Amiodarone results in increased expression of ZNF420 mRNA
CTD
PMID:19774075
NCBI chr 1:85,092,810...85,143,682
Ensembl chr 1:85,093,085...85,106,693 Ensembl chr 1:85,093,085...85,106,693
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Zfp560
zinc finger protein 560
increases expression
ISO
Amiodarone results in increased expression of ZNF121 mRNA
CTD
PMID:19774075
NCBI chr 8:18,900,142...18,914,444
Ensembl chr 8:18,900,528...18,914,442
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Zfp592
zinc finger protein 592
increases expression
ISO
Amiodarone results in increased expression of ZNF592 mRNA
CTD
PMID:19774075
NCBI chr 1:134,951,286...135,002,443
Ensembl chr 1:134,967,783...135,002,443
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Zfp683
zinc finger protein 683
increases expression
ISO
Amiodarone results in increased expression of ZNF683 mRNA
CTD
PMID:19774075
NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000
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Zfp703
zinc finger protein 703
increases expression
ISO
Amiodarone results in increased expression of ZNF703 mRNA
CTD
PMID:19774075
NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677
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Zfp704
zinc finger protein 704
increases expression
ISO
Amiodarone results in increased expression of ZNF704 mRNA
CTD
PMID:19774075
NCBI chr 2:92,171,804...92,356,059
Ensembl chr 2:92,171,496...92,351,282
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Zfp710
zinc finger protein 710
increases expression
ISO
Amiodarone results in increased expression of ZNF710 mRNA
CTD
PMID:19774075
NCBI chr 1:133,966,256...134,036,593
Ensembl chr 1:134,024,267...134,036,601
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Zfp771
zinc finger protein 771
increases expression
ISO
Amiodarone results in increased expression of ZNF771 mRNA
CTD
PMID:19774075
NCBI chr 1:181,864,035...181,875,136
Ensembl chr 1:181,864,219...181,875,141
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Zmynd10
zinc finger, MYND-type containing 10
increases expression
ISO
Amiodarone results in increased expression of ZMYND10 mRNA
CTD
PMID:19774075
NCBI chr 8:108,220,386...108,224,745
Ensembl chr 8:108,220,386...108,224,744
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Znf624l
zinc finger protein 624 like
increases expression
ISO
Amiodarone results in increased expression of ZNF624 mRNA
CTD
PMID:19774075
NCBI chr 7:7,853,363...7,890,995
Ensembl chr 7:7,853,403...7,890,974
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Znhit2
zinc finger, HIT-type containing 2
increases expression
ISO
Amiodarone results in increased expression of ZNHIT2 mRNA
CTD
PMID:19774075
NCBI chr 1:203,354,297...203,355,578
Ensembl chr 1:203,354,138...203,355,636
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Zscan20
zinc finger and SCAN domain containing 20
increases expression
ISO
Amiodarone results in increased expression of ZSCAN20 mRNA
CTD
PMID:19774075
NCBI chr 5:140,926,596...140,956,285
Ensembl chr 5:140,930,689...140,956,336
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Zwint
ZW10 interacting kinetochore protein
affects expression
EXP
Amiodarone affects the expression of ZWINT mRNA
CTD
PMID:19483382
NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
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Zxda
zinc finger, X-linked, duplicated A
increases expression
ISO
Amiodarone results in increased expression of ZXDA mRNA
CTD
PMID:19774075
NCBI chr X:59,760,871...59,766,010
Ensembl chr X:59,763,210...59,765,903
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