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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:amiodarone
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Accession:CHEBI:2663 term browser browse the term
Definition:A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Synonyms:exact_synonym: (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
 related_synonym: 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran;   2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone;   2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran;   Formula=C25H29I2NO3;   InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;   InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N;   SMILES=CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1;   amiodarona;   amiodaronum
 xref: Beilstein:1271711;   CAS:1951-25-3;   DrugBank:DB01118;   Drug_Central:176;   HMDB:HMDB0015250;   KEGG:C06823;   KEGG:D02910;   LINCS:LSM-2379
 xref_mesh: MESH:D000638
 xref: PMID:10188629;   PMID:16479044;   PMID:18368867;   Patent:CA2826272;   Patent:TW201400111;   Wikipedia:Amiodarone



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amiodarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase affects expression EXP Amiodarone affects the expression of AADAT mRNA CTD PMID:18355885 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Amiodarone results in decreased expression of ABCA1 mRNA CTD PMID:29248575 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca2 ATP binding cassette subfamily A member 2 increases expression ISO Amiodarone results in increased expression of ABCA2 mRNA CTD PMID:19774075 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression
decreases activity
ISO
EXP
Amiodarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Amiodarone results in decreased expression of ABCB11 mRNA
Amiodarone results in decreased activity of ABCB11 protein
CTD PMID:20829430 PMID:24014644 PMID:27765674 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects expression
affects response to substance
decreases activity
ISO
EXP
Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]
Amiodarone affects the expression of ABCB1 mRNA; Amiodarone affects the expression of ABCB1A mRNA
Amiodarone inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
ABCB1A protein affects the susceptibility to Amiodarone
Amiodarone results in decreased activity of ABCB1 protein
CTD PMID:11231118 PMID:12235267 PMID:15502009 PMID:18355885 PMID:19483382 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects response to substance ISO ABCB1B protein affects the susceptibility to Amiodarone CTD PMID:15502009 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
decreases expression
ISO
EXP
Amiodarone results in increased expression of ABCB4 mRNA
Amiodarone results in decreased expression of ABCB4 mRNA
CTD PMID:24489787 PMID:27765674 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Amiodarone results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression
ISO
EXP
Amiodarone results in increased expression of ABCC3 mRNA
Amiodarone results in decreased expression of ABCC3 mRNA
CTD PMID:24489787 PMID:27765674 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression EXP Amiodarone results in decreased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects expression EXP Amiodarone affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression ISO Amiodarone results in increased expression of ABCD3 mRNA CTD PMID:24489787 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 increases expression ISO Amiodarone results in increased expression of ABCD4 mRNA CTD PMID:24489787 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression
increases expression
EXP Amiodarone affects the expression of ABCG5 mRNA
Amiodarone results in increased expression of ABCG5 mRNA
CTD PMID:19483382 PMID:27765674 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Amiodarone affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Amiodarone affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Amiodarone affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Amiodarone results in increased expression of ABL1 mRNA CTD PMID:19774075 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065
JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Amiodarone results in increased expression of ACAA1 mRNA CTD PMID:15265979 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of ACACA mRNA
Amiodarone results in increased expression of ACACA mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression EXP
ISO
Amiodarone results in increased expression of ACACB mRNA CTD PMID:19224547 PMID:24489787 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acad10 acyl-CoA dehydrogenase family, member 10 increases expression ISO Amiodarone results in increased expression of ACAD10 mRNA CTD PMID:24535564 NCBI chr12:34,901,211...34,943,973
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 increases expression ISO Amiodarone results in increased expression of ACAD9 mRNA CTD PMID:24489787 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Amiodarone affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO Amiodarone results in increased expression of ACADM mRNA CTD PMID:24489787 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression ISO Amiodarone results in increased expression of ACAT1 mRNA CTD PMID:24489787 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression EXP Amiodarone results in increased expression of ACAT2 mRNA CTD PMID:32084307 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Amiodarone results in increased expression of ACER2 mRNA CTD PMID:25580480 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
JBrowse link
G Acly ATP citrate lyase increases expression ISO
EXP
Amiodarone results in increased expression of ACLY mRNA CTD PMID:32084307 PMID:32535746 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Aco1 aconitase 1 affects expression EXP Amiodarone affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 affects expression EXP Amiodarone affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO
EXP
Amiodarone results in increased expression of ACOT1 mRNA CTD PMID:24489787 PMID:24535564 PMID:30685923 PMID:32084307 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of ACOT12 mRNA
Amiodarone results in increased expression of ACOT12 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Amiodarone results in increased expression of ACOT2 mRNA CTD PMID:24489787 PMID:24535564 PMID:30685923 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO Amiodarone results in increased expression of ACOT3 mRNA CTD PMID:24535564 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
Ensembl chr 6:103,682,596...103,688,427
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Amiodarone affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Acot8 acyl-CoA thioesterase 8 increases expression ISO Amiodarone results in increased expression of ACOT8 mRNA CTD PMID:19774075 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851
JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Amiodarone results in increased expression of ACOX1 mRNA CTD PMID:15265979 PMID:30685923 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acox2 acyl-CoA oxidase 2 increases expression ISO Amiodarone results in increased expression of ACOX2 mRNA CTD PMID:24489787 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
JBrowse link
G Acsf3 acyl-CoA synthetase family member 3 increases expression ISO Amiodarone results in increased expression of ACSF3 mRNA CTD PMID:19774075 NCBI chr19:50,835,116...50,875,557
Ensembl chr19:50,835,221...50,875,553
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP Amiodarone results in increased expression of ACSL3 mRNA CTD PMID:32084307 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO
EXP
Amiodarone results in increased expression of ACSS2 mRNA CTD PMID:24535564 PMID:32084307 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein]
Amiodarone results in increased expression of ACTA2 mRNA; Amiodarone results in increased expression of ACTA2 protein
CTD PMID:31071512 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actr3b actin related protein 3B increases expression ISO Amiodarone results in increased expression of ACTR3B mRNA CTD PMID:19774075 NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441
JBrowse link
G Acvr1b activin A receptor type 1B increases expression ISO Amiodarone results in increased expression of ACVR1B mRNA CTD PMID:19774075 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673
JBrowse link
G Acyp1 acylphosphatase 1 increases expression ISO Amiodarone results in increased expression of ACYP1 mRNA CTD PMID:19774075 NCBI chr 6:104,919,162...104,932,348
Ensembl chr 6:104,919,162...104,932,387
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Amiodarone affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Add1 adducin 1 affects expression EXP Amiodarone affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO Amiodarone results in increased expression of ADGRD1 mRNA CTD PMID:19774075 NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696
JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO Amiodarone results in decreased expression of ADGRF1 mRNA CTD PMID:24535564 NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Amiodarone affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adm2 adrenomedullin 2 multiple interactions ISO ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]] CTD PMID:34434487 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331
JBrowse link
G Adora3 adenosine A3 receptor increases expression ISO Amiodarone results in increased expression of ADORA3 mRNA CTD PMID:19774075 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression ISO Amiodarone results in increased expression of ADRA2A mRNA CTD PMID:19774075 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
JBrowse link
G Adrb1 adrenoceptor beta 1 decreases expression ISO Amiodarone results in decreased expression of ADRB1 protein CTD PMID:1653643 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression ISO Amiodarone results in decreased expression of ADRB2 protein CTD PMID:1653643 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions EXP Amiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein] CTD PMID:10217540 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Amiodarone affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Afm afamin affects expression EXP Amiodarone affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Afp alpha-fetoprotein increases expression ISO Amiodarone results in increased expression of AFP mRNA CTD PMID:24489787 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Agt angiotensinogen increases expression
affects expression
multiple interactions
ISO
EXP
Amiodarone results in increased expression of AGT mRNA; Amiodarone results in increased expression of AGT protein
Amiodarone affects the expression of AGT mRNA
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD PMID:17214612 PMID:19483382 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Amiodarone affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Amiodarone results in increased expression of AHNAK mRNA CTD PMID:19774075 NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Ahr aryl hydrocarbon receptor affects expression ISO Amiodarone affects the expression of AHR mRNA CTD PMID:35641671 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Amiodarone results in increased expression of AIFM1 mRNA CTD PMID:24489787 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Ak4 adenylate kinase 4 increases expression EXP Amiodarone results in increased expression of AK4 protein CTD PMID:16538043 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Amiodarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Amiodarone results in increased expression of AKR1C1 mRNA CTD PMID:21163907 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Amiodarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Amiodarone affects the expression of AKR7A3 mRNA CTD PMID:19483382 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Amiodarone results in decreased phosphorylation of AKT1 protein CTD PMID:23912912 PMID:26515726 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Amiodarone results in increased expression of ALAS1 mRNA CTD PMID:19774075 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression ISO Amiodarone results in decreased expression of ALAS2 mRNA CTD PMID:24535564 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Alb albumin increases expression ISO Amiodarone results in increased expression of ALB mRNA CTD PMID:19774075 PMID:36586010 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Amiodarone affects the expression of ALDH1A1 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Amiodarone affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression ISO Amiodarone results in increased expression of ALDH3A2 mRNA CTD PMID:24535564 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression EXP Amiodarone results in increased expression of ALDH6A1 mRNA CTD PMID:17991464 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression ISO Amiodarone results in increased expression of ALG12 mRNA CTD PMID:19774075 NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase increases expression ISO Amiodarone results in increased expression of ALG2 mRNA CTD PMID:19774075 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297
JBrowse link
G Alk ALK receptor tyrosine kinase increases expression ISO Amiodarone results in increased expression of ALK mRNA CTD PMID:19774075 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034
JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression ISO Amiodarone results in increased expression of ALKAL1 mRNA CTD PMID:19774075 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948
JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Amiodarone affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 increases expression ISO Amiodarone results in increased expression of AMIGO1 mRNA CTD PMID:19774075 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Amiodarone results in decreased expression of ANGPTL3 mRNA CTD PMID:27089845 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Amiodarone results in increased expression of ANGPTL4 mRNA CTD PMID:24489787 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Anxa4 annexin A4 increases expression ISO Amiodarone results in increased expression of ANXA4 mRNA CTD PMID:19774075 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression
increases expression
ISO Amiodarone results in decreased expression of AP1S1 mRNA
Amiodarone results in increased expression of AP1S1 mRNA
CTD PMID:17175557 PMID:17567588 PMID:29248575 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Amiodarone affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Apcs amyloid P component, serum affects expression EXP Amiodarone affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Amiodarone affects the expression of APOA4 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoa5 apolipoprotein A5 increases expression ISO Amiodarone results in increased expression of APOA5 mRNA CTD PMID:24489787 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
JBrowse link
G Apob apolipoprotein B decreases expression ISO Amiodarone results in decreased expression of APOB mRNA CTD PMID:29248575 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
JBrowse link
G Apoc2 apolipoprotein C2 increases expression ISO Amiodarone results in increased expression of APOC2 mRNA CTD PMID:24489787 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
JBrowse link
G Apoe apolipoprotein E decreases expression EXP Amiodarone results in decreased expression of APOE mRNA CTD PMID:17991464 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Apoh apolipoprotein H affects expression EXP Amiodarone affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Apool apolipoprotein O-like affects expression EXP Amiodarone affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:77,377,723...77,443,672
Ensembl chr  X:77,377,781...77,443,900
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO Amiodarone results in increased expression of ARC mRNA CTD PMID:19774075 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Arg1 arginase 1 affects expression EXP Amiodarone affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arhgap15 Rho GTPase activating protein 15 increases expression ISO Amiodarone results in increased expression of ARHGAP15 mRNA CTD PMID:19774075 NCBI chr 3:27,989,368...28,592,722
Ensembl chr 3:27,989,633...28,600,265
JBrowse link
G Arhgap35 Rho GTPase activating protein 35 increases expression ISO Amiodarone results in increased expression of ARHGAP35 mRNA CTD PMID:19774075 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298
JBrowse link
G Arhgap4 Rho GTPase activating protein 4 increases expression ISO Amiodarone results in increased expression of ARHGAP4 mRNA CTD PMID:19774075 NCBI chr  X:151,636,071...151,651,528
Ensembl chr  X:151,632,454...151,651,128
JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases expression ISO Amiodarone results in increased expression of ARHGAP45 mRNA CTD PMID:19774075 NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases expression ISO Amiodarone results in increased expression of ARHGAP9 mRNA CTD PMID:19774075 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
JBrowse link
G Arhgef10l Rho guanine nucleotide exchange factor 10 like increases expression ISO Amiodarone results in increased expression of ARHGEF10L mRNA CTD PMID:19774075 NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538
JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 increases expression ISO Amiodarone results in increased expression of ARHGEF7 mRNA CTD PMID:19774075 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697
JBrowse link
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 increases expression ISO Amiodarone results in increased expression of ARHGEF9 mRNA CTD PMID:19774075 NCBI chr  X:59,919,560...60,077,538
Ensembl chr  X:59,920,870...60,077,513
JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Amiodarone results in increased expression of ARID5A mRNA CTD PMID:19774075 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 affects expression EXP Amiodarone affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
JBrowse link
G Armc9 armadillo repeat containing 9 increases expression ISO Amiodarone results in increased expression of ARMC9 mRNA CTD PMID:19774075 NCBI chr 9:86,802,791...86,928,611
Ensembl chr 9:86,802,868...86,928,860
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Amiodarone results in increased expression of ARPC4 mRNA CTD PMID:19774075 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression EXP
ISO
Amiodarone results in increased expression of ASAH1 mRNA CTD PMID:15342952 PMID:17567588 PMID:19224547 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Asb7 ankyrin repeat and SOCS box-containing 7 increases expression ISO Amiodarone results in increased expression of ASB7 mRNA CTD PMID:19774075 NCBI chr 1:120,222,835...120,267,411
Ensembl chr 1:120,222,745...120,267,282
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Amiodarone affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Amiodarone results in increased expression of ASNS mRNA CTD PMID:17175557 PMID:17567588 PMID:36586010 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO Amiodarone results in increased expression of ATF3 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone promotes the reaction [Amiodarone results in increased expression of ATF3 mRNA]
CTD PMID:19774075 PMID:34259586 PMID:36586010 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atf4 activating transcription factor 4 increases expression
decreases expression
multiple interactions
ISO Amiodarone results in increased expression of ATF4 mRNA; Amiodarone results in increased expression of ATF4 protein
Amiodarone results in decreased expression of ATF4 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of ATF4 mRNA]
CTD PMID:21292685 PMID:28962527 PMID:34259586 PMID:35641671 PMID:36586010 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Amiodarone affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO Amiodarone results in increased expression of and affects the localization of ATF6 protein CTD PMID:28962527 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Amiodarone results in increased expression of ATF6B mRNA CTD PMID:19774075 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894
JBrowse link
G Atg5 autophagy related 5 affects response to substance ISO ATG5 protein affects the susceptibility to Amiodarone CTD PMID:32651653 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 increases expression
affects response to substance
multiple interactions
ISO Amiodarone results in increased expression of ATG7 protein
ATG7 protein affects the susceptibility to Amiodarone
ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]
CTD PMID:23912912 PMID:32651653 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atoh1 atonal bHLH transcription factor 1 increases expression ISO Amiodarone results in increased expression of ATOH1 mRNA CTD PMID:19774075 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154
JBrowse link
G Atp11c ATPase phospholipid transporting 11C increases expression ISO Amiodarone results in increased expression of ATP11C mRNA CTD PMID:19774075 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Amiodarone results in decreased expression of ATP1A1 protein CTD PMID:8071999 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression EXP Amiodarone results in decreased expression of ATP1A2 mRNA; Amiodarone results in decreased expression of ATP1A2 protein CTD PMID:7573397 PMID:8071999 PMID:12479229 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Amiodarone results in decreased expression of ATP1B1 protein CTD PMID:8071999 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Amiodarone results in decreased expression of ATP1B2 mRNA CTD PMID:8071999 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Amiodarone results in decreased expression of ATP2A2 mRNA CTD PMID:17535870 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP Amiodarone results in increased expression of ATP5F1B mRNA CTD PMID:17991464 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Amiodarone affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Amiodarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Amiodarone affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Amiodarone affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Amiodarone affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bag1 BAG cochaperone 1 increases expression ISO Amiodarone results in increased expression of BAG1 mRNA CTD PMID:19774075 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075
JBrowse link
G Bag3 BAG cochaperone 3 decreases expression EXP Amiodarone results in decreased expression of BAG3 mRNA CTD PMID:17991464 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 increases expression ISO Amiodarone results in increased expression of BAIAP2L1 mRNA CTD PMID:19774075 NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Amiodarone results in increased expression of BAX mRNA; Amiodarone results in increased expression of BAX protein
ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]
CTD PMID:12084619 PMID:34434487 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Amiodarone results in increased expression of BBC3 mRNA CTD PMID:36586010 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 increases expression ISO Amiodarone results in increased expression of BBOX1 mRNA CTD PMID:19774075 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha increases expression EXP Amiodarone results in increased expression of BCKDHA protein CTD PMID:16538043 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
EXP
ISO
Amiodarone results in decreased expression of BCL2 protein
Amiodarone results in decreased expression of BCL2 mRNA; Amiodarone results in decreased expression of BCL2 protein
[3-methyladenine co-treated with Amiodarone] results in decreased expression of BCL2 protein; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]
CTD PMID:21224497 PMID:23912912 PMID:34434487 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO Amiodarone results in increased expression of BCL2L11 mRNA CTD PMID:19774075 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression EXP Amiodarone results in increased expression of BCL3 mRNA CTD PMID:22015988 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Amiodarone affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bco1 beta-carotene oxygenase 1 decreases expression ISO Amiodarone results in decreased expression of BCO1 mRNA CTD PMID:24535564 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
JBrowse link
G Bdnf brain-derived neurotrophic factor affects expression EXP Amiodarone affects the expression of BDNF mRNA CTD PMID:31324950 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Amiodarone results in increased expression of BHLHE40 mRNA CTD PMID:19774075 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase affects expression EXP Amiodarone affects the expression of BHMT mRNA CTD PMID:18355885 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein CTD PMID:21292685 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP Amiodarone results in decreased expression of BIRC5 protein CTD PMID:21224497 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B affects expression EXP Amiodarone affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Amiodarone affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bmp2k BMP-2 inducible kinase increases expression ISO Amiodarone results in increased expression of BMP2K mRNA CTD PMID:19774075 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Amiodarone affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Bola2 bolA family member 2 increases expression ISO Amiodarone results in increased expression of BOLA2 mRNA CTD PMID:19774075 NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676
JBrowse link
G Boll boule homolog, RNA binding protein increases expression ISO Amiodarone results in increased expression of BOLL mRNA CTD PMID:19774075 NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916
JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO Amiodarone results in increased expression of BRCA1 mRNA CTD PMID:24489787 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 increases expression ISO Amiodarone results in increased expression of BRCC3 mRNA CTD PMID:19774075 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080
JBrowse link
G Brpf1 bromodomain and PHD finger containing, 1 increases expression ISO Amiodarone results in increased expression of BRPF1 mRNA CTD PMID:19774075 NCBI chr 4:146,456,325...146,472,781
Ensembl chr 4:146,456,318...146,472,649
JBrowse link
G Bsg basigin increases expression ISO Amiodarone results in increased expression of BSG mRNA CTD PMID:19774075 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Amiodarone affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G C11h21orf91 similar to human chromosome 21 open reading frame 91 increases expression ISO Amiodarone results in increased expression of C21ORF91 mRNA CTD PMID:19774075 NCBI chr11:17,229,129...17,262,307
Ensembl chr11:17,229,138...17,262,483
JBrowse link
G C19h16orf74 similar to human chromosome 16 open reading frame 74 increases expression ISO Amiodarone results in increased expression of C16ORF74 mRNA CTD PMID:19774075 NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349
JBrowse link
G C1h11orf16 similar to human chromosome 11 open reading frame 16 increases expression ISO Amiodarone results in increased expression of C11ORF16 mRNA CTD PMID:19774075 NCBI chr 1:163,742,987...163,754,920
Ensembl chr 1:163,743,021...163,754,089
JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Amiodarone affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C1s complement C1s affects expression EXP Amiodarone affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Amiodarone affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression ISO Amiodarone results in increased expression of NLF2 mRNA CTD PMID:19774075 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328
JBrowse link
G C2h3orf33 similar to human chromosome 3 open reading frame 33 increases expression ISO Amiodarone results in increased expression of C3ORF33 mRNA CTD PMID:19774075 NCBI chr 2:148,376,598...148,404,343
Ensembl chr 2:148,380,581...148,404,387
JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression EXP Amiodarone affects the expression of C4BPA mRNA CTD PMID:19483382 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C7 complement C7 affects expression EXP Amiodarone affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G C8b complement C8 beta chain affects expression
decreases expression
EXP
ISO
Amiodarone affects the expression of C8B mRNA
Amiodarone results in decreased expression of C8B mRNA
CTD PMID:19483382 PMID:24535564 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G C8h3orf18 similar to human chromosome 3 open reading frame 18 increases expression ISO Amiodarone results in increased expression of C3ORF18 mRNA CTD PMID:19774075 NCBI chr 8:108,012,638...108,022,050
Ensembl chr 8:108,012,638...108,022,461
JBrowse link
G C9h6orf141 similar to human chromosome 6 open reading frame 141 increases expression ISO Amiodarone results in increased expression of C6ORF141 mRNA CTD PMID:19774075 NCBI chr 9:20,024,916...20,029,094
Ensembl chr 9:20,024,916...20,029,094
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C decreases expression ISO Amiodarone results in decreased expression of CACNA1C mRNA CTD PMID:15520326 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Amiodarone affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
JBrowse link
G Calr calreticulin increases expression ISO Amiodarone results in increased expression of CALR mRNA CTD PMID:36586010 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO Amiodarone results in increased expression of CAMK2A mRNA CTD PMID:19774075 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
JBrowse link
G Capn11 calpain 11 increases expression ISO Amiodarone results in increased expression of CAPN11 mRNA CTD PMID:19774075 NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601
JBrowse link
G Capn3 calpain 3 increases expression ISO Amiodarone results in increased expression of CAPN3 mRNA CTD PMID:19774075 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Amiodarone affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Amiodarone affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Car3 carbonic anhydrase 3 affects expression
increases expression
EXP Amiodarone affects the expression of CAR3 mRNA
Amiodarone results in increased expression of CAR3 protein
CTD PMID:16538043 PMID:19483382 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Card9 caspase recruitment domain family, member 9 increases expression ISO Amiodarone results in increased expression of CARD9 mRNA CTD PMID:19774075 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Caskin2 cask-interacting protein 2 increases expression ISO Amiodarone results in increased expression of CASKIN2 mRNA CTD PMID:19774075 NCBI chr10:101,027,196...101,041,429
Ensembl chr10:101,027,260...101,041,414
JBrowse link
G Casp3 caspase 3 affects expression
increases cleavage
increases activity
increases expression
decreases expression
multiple interactions
EXP
ISO
Amiodarone affects the expression of CASP3 mRNA
Amiodarone results in increased cleavage of CASP3 protein
Amiodarone results in increased activity of CASP3 protein
Amiodarone results in increased expression of CASP3 mRNA
Amiodarone results in decreased expression of CASP3 protein modified form
3-methyladenine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP3 protein; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; Amiodarone results in increased activity of and results in increased cleavage of CASP3 protein; ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]
Amiodarone results in increased expression of CASP3 mRNA; Amiodarone results in increased expression of CASP3 protein
CTD PMID:12084619 PMID:12747577 PMID:19483382 PMID:19815060 PMID:21224497 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases expression
increases activity
ISO alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]
Amiodarone results in increased expression of CASP7 mRNA
CTD PMID:23042730 PMID:23135547 PMID:24489787 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
ISO
EXP
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein
Amiodarone results in increased expression of CASP8 protein modified form
CTD PMID:21224497 PMID:21292685 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
ISO Amiodarone results in increased expression of CASP9 mRNA
[Amiodarone co-treated with TNF protein] results in increased activity of CASP9 protein
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP9 protein
CTD PMID:19774075 PMID:21292685 PMID:23042730 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression
EXP
ISO
Amiodarone inhibits the reaction [Indomethacin results in increased activity of CAT protein]
Amiodarone results in decreased activity of CAT protein
Amiodarone results in decreased expression of CAT mRNA
ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]
CTD PMID:18087811 PMID:34434487 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav3 caveolin 3 increases expression ISO Amiodarone results in increased expression of CAV3 mRNA CTD PMID:19774075 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP Amiodarone affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Ccdc134 coiled-coil domain containing 134 increases expression ISO Amiodarone results in increased expression of CCDC134 mRNA CTD PMID:19774075 NCBI chr 7:113,644,557...113,659,050
Ensembl chr 7:113,644,639...113,659,050
JBrowse link
G Ccdc17 coiled-coil domain containing 17 increases expression ISO Amiodarone results in increased expression of CCDC17 mRNA CTD PMID:19774075 NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673
JBrowse link
G Ccdc9 coiled-coil domain containing 9 increases expression ISO Amiodarone results in increased expression of CCDC9 mRNA CTD PMID:19774075 NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607
JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression ISO Amiodarone results in increased expression of CFAP184 mRNA CTD PMID:19774075 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
ISO Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]
[Amiodarone co-treated with Dexamethasone] results in increased expression of CCL2 mRNA
Amiodarone results in increased expression of CCL2 mRNA
CTD PMID:19225199 PMID:23397585 PMID:25900201 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP Amiodarone results in increased expression of CCN2 mRNA CTD PMID:32909452 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnt1 cyclin T1 increases expression ISO Amiodarone results in increased expression of CCNT1 mRNA CTD PMID:19774075 NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
JBrowse link
G Ccr9 C-C motif chemokine receptor 9 increases expression ISO Amiodarone results in increased expression of CCR9 mRNA CTD PMID:19774075 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
JBrowse link
G Cd320 CD320 molecule increases expression ISO Amiodarone results in increased expression of CD320 mRNA CTD PMID:19774075 NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976
JBrowse link
G Cd36 CD36 molecule increases expression
decreases expression
ISO Amiodarone results in increased expression of CD36 mRNA; Amiodarone results in increased expression of CD36 protein
Amiodarone results in decreased expression of CD36 mRNA
CTD PMID:24535564 PMID:29248575 PMID:32535746 PMID:34259586 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein CTD PMID:22785256 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cda cytidine deaminase increases expression ISO Amiodarone results in increased expression of CDA mRNA CTD PMID:24535564 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO Amiodarone results in increased expression of CDC25A mRNA CTD PMID:19774075 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression ISO Amiodarone results in increased expression of CDC42SE1 mRNA CTD PMID:19774075 NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028
JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
ISO Amiodarone results in increased expression of CDH1 protein
6-bromoindirubin-3'-oxime inhibits the reaction [Amiodarone results in increased expression of CDH1 protein]
CTD PMID:26515726 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh15 cadherin 15 increases expression ISO Amiodarone results in increased expression of CDH15 mRNA CTD PMID:19774075 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO Amiodarone results in decreased expression of CDH2 protein CTD PMID:26515726 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdh26 cadherin 26 increases expression ISO Amiodarone results in increased expression of CDH26 mRNA CTD PMID:19774075 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149
JBrowse link
G Cdk17 cyclin-dependent kinase 17 increases expression ISO Amiodarone results in increased expression of CDK17 mRNA CTD PMID:19774075 NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression EXP Amiodarone affects the expression of CDKN2C mRNA CTD PMID:18355885 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Amiodarone affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO
EXP
Amiodarone results in increased expression of CEBPB mRNA CTD PMID:19774075 PMID:25580480 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression ISO Amiodarone results in increased expression of CELF6 mRNA CTD PMID:19774075 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Amiodarone affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Amiodarone results in increased expression of CES1 mRNA CTD PMID:21163907 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Amiodarone affects the expression of CES2 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfi complement factor I affects expression EXP Amiodarone affects the expression of CFI mRNA CTD PMID:19483382 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression EXP Amiodarone results in decreased expression of CFLAR protein CTD PMID:21224497 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression EXP Amiodarone results in increased expression of CGA mRNA CTD PMID:3427795 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Amiodarone results in increased expression of CHAC1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression EXP Amiodarone results in decreased expression of CHAF1A mRNA CTD PMID:17991464 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654
JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP Amiodarone results in decreased expression of CHAT protein CTD PMID:25659768 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
JBrowse link
G Chga chromogranin A increases expression ISO Amiodarone results in increased expression of CHGA mRNA CTD PMID:19774075 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Amiodarone affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO Amiodarone results in increased expression of CHRNB3 mRNA CTD PMID:19774075 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360
JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression ISO Amiodarone results in increased expression of CHST6 mRNA CTD PMID:19774075 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064
JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions
increases expression
ISO 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA] CTD PMID:28962527 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression
multiple interactions
ISO Amiodarone results in increased expression of CIDEC mRNA; Amiodarone results in increased expression of CIDEC protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]
CTD PMID:28962527 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Cimap3 ciliary microtubule associated protein 3 increases expression ISO Amiodarone results in increased expression of CIMAP3 mRNA CTD PMID:19774075 NCBI chr 2:193,475,785...193,493,092
Ensembl chr 2:193,475,782...193,493,139
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Amiodarone affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Amiodarone affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression ISO Amiodarone results in increased expression of CLCN5 mRNA CTD PMID:19774075 NCBI chr  X:15,185,380...15,339,977
Ensembl chr  X:15,185,451...15,334,264
JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression ISO Amiodarone results in increased expression of CLCN6 mRNA CTD PMID:19774075 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Amiodarone affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Amiodarone affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO Amiodarone results in increased expression of CLPX mRNA CTD PMID:24535564 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082
JBrowse link
G Clvs2 clavesin 2 increases expression ISO Amiodarone results in increased expression of CLVS2 mRNA CTD PMID:19774075 NCBI chr 1:23,735,660...23,842,685
Ensembl chr 1:23,735,272...23,842,692
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of CMBL mRNA
Amiodarone results in increased expression of CMBL mRNA
CTD PMID:19483382 PMID:24535564 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Amiodarone affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 affects expression EXP Amiodarone affects the expression of CMTM6 mRNA CTD PMID:18355885 NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033
JBrowse link
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 increases expression ISO Amiodarone results in increased expression of CMTM7 mRNA CTD PMID:19774075 NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621
JBrowse link
G Cmya5 cardiomyopathy associated 5 increases expression ISO Amiodarone results in increased expression of CMYA5 mRNA CTD PMID:19774075 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364
JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 increases expression ISO Amiodarone results in increased expression of CNIH3 mRNA CTD PMID:19774075 NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121
JBrowse link
G Cnnm2 cyclin and CBS domain divalent metal cation transport mediator 2 increases expression ISO Amiodarone results in increased expression of CNNM2 mRNA CTD PMID:19774075 NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286
JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 increases expression ISO Amiodarone results in increased expression of CNOT7 mRNA CTD PMID:19774075 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576
JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression ISO Amiodarone results in increased expression of CNP mRNA CTD PMID:19774075 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720
JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression ISO Amiodarone results in increased expression of COL11A1 mRNA CTD PMID:19774075 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Amiodarone results in increased expression of COL1A1 mRNA CTD PMID:32909452 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col27a1 collagen type XXVII alpha 1 chain increases expression ISO Amiodarone results in increased expression of COL27A1 mRNA CTD PMID:19774075 NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174
JBrowse link
G Col8a2 collagen type VIII alpha 2 chain increases expression ISO Amiodarone results in increased expression of COL8A2 mRNA CTD PMID:19774075 NCBI chr 5:138,586,201...138,613,627
Ensembl chr 5:138,585,999...138,612,850
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Amiodarone affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Amiodarone affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
JBrowse link
G Copz2 COPI coat complex subunit zeta 2 increases expression ISO Amiodarone results in increased expression of COPZ2 mRNA CTD PMID:24535564 NCBI chr10:81,832,441...81,845,514
Ensembl chr10:81,832,418...81,845,514
JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase increases expression ISO Amiodarone results in increased expression of COQ2 mRNA CTD PMID:24489787 NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of COQ3 mRNA
Amiodarone results in increased expression of COQ3 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Coro2a coronin 2A increases expression ISO Amiodarone results in increased expression of CORO2A mRNA CTD PMID:19774075 NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035
JBrowse link
G Cort cortistatin affects expression EXP Amiodarone affects the expression of CORT mRNA CTD PMID:31324950 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 increases expression ISO Amiodarone results in increased expression of COX15 mRNA CTD PMID:24489787 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases expression ISO Amiodarone results in increased expression of COX17 mRNA CTD PMID:24489787 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Amiodarone affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cox6b2 cytochrome c oxidase subunit 6B2 increases expression ISO Amiodarone results in increased expression of COX6B2 mRNA CTD PMID:24535564 NCBI chr 1:69,094,009...69,095,312 JBrowse link
G Cplx2 complexin 2 increases expression ISO Amiodarone results in increased expression of CPLX2 mRNA CTD PMID:19774075 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Amiodarone affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
JBrowse link
G Cpped1 calcineurin-like phosphoesterase domain containing 1 affects expression EXP Amiodarone affects the expression of CPPED1 mRNA CTD PMID:18355885 NCBI chr10:3,701,522...3,821,050
Ensembl chr10:3,701,459...3,821,054
JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Amiodarone affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
decreases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of CPT1A mRNA
Amiodarone results in decreased expression of CPT1A mRNA
Amiodarone affects the expression of CPT1A mRNA
CTD PMID:24489787 PMID:29248575 PMID:32084307 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression
decreases expression
ISO
EXP
Amiodarone results in increased expression of CPT2 mRNA
Amiodarone results in decreased expression of CPT2 mRNA
CTD PMID:24489787 PMID:30685923 PMID:32084307 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
JBrowse link
G Crb3 crumbs cell polarity complex component 3 increases expression ISO Amiodarone results in increased expression of CRB3 mRNA CTD PMID:19774075 NCBI chr 9:1,898,531...1,903,860
Ensembl chr 9:1,896,623...1,903,859
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Amiodarone affects the expression of CREM mRNA CTD PMID:18355885 PMID:19483382 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression ISO Amiodarone results in decreased expression of CROT mRNA CTD PMID:27089845 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Crp C-reactive protein multiple interactions ISO Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]; Amiodarone inhibits the reaction [CRP protein results in increased expression of TNF protein] CTD PMID:19225199 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 decreases expression EXP Amiodarone results in decreased expression of CRTC1 mRNA CTD PMID:17991464 NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381
JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Amiodarone affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Amiodarone affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression ISO Amiodarone results in increased expression of CSRP3 mRNA CTD PMID:24535564 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
JBrowse link
G Cst6 cystatin E/M increases expression ISO Amiodarone results in increased expression of CST6 mRNA CTD PMID:19774075 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
JBrowse link
G Cst7 cystatin F increases expression ISO Amiodarone results in increased expression of CST7 mRNA CTD PMID:19774075 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557
JBrowse link
G Ctc1 CST telomere replication complex component 1 increases expression ISO Amiodarone results in increased expression of CTC1 mRNA CTD PMID:19774075 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298
JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 increases expression ISO Amiodarone results in increased expression of CTLA4 mRNA CTD PMID:19774075 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Amiodarone affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]] CTD PMID:34434487 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Ctsb cathepsin B affects cleavage ISO Amiodarone affects the cleavage of CTSB protein CTD PMID:25881747 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsd cathepsin D affects cleavage ISO Amiodarone affects the cleavage of CTSD protein CTD PMID:25881747 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Ctsl cathepsin L affects cleavage ISO Amiodarone affects the cleavage of CTSL protein CTD PMID:25881747 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Amiodarone inhibits the reaction [Dexamethasone results in increased expression of CXCL2 mRNA] CTD PMID:25900201 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
increases response to substance
multiple interactions
EXP
ISO
Amiodarone results in increased expression of CYP1A1 mRNA
Amiodarone results in decreased activity of CYP1A1 protein
CYP1A1 protein results in increased susceptibility to Amiodarone
Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD PMID:19224547 PMID:20362646 PMID:26477383 PMID:32084307 PMID:33814510 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
multiple interactions
decreases response to substance
ISO Amiodarone results in decreased activity of CYP1A2 protein
[Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin
CYP1A2 protein results in decreased susceptibility to Amiodarone
CTD PMID:16449812 PMID:26477383 PMID:26599973 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases response to substance
decreases activity
ISO CYP1B1 protein results in decreased susceptibility to Amiodarone
Amiodarone results in decreased activity of CYP1B1 protein
CTD PMID:26477383 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Amiodarone results in increased expression of CYP26A1 mRNA CTD PMID:19774075 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression
increases expression
EXP Amiodarone affects the expression of CYP2A1 mRNA
Amiodarone results in increased expression of CYP2A1 mRNA
CTD PMID:18355885 PMID:19483382 PMID:32084307 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Amiodarone affects the expression of CYP2B15 mRNA CTD PMID:18355885 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression EXP Amiodarone affects the expression of CYP2B2 mRNA CTD PMID:19483382 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression
increases expression
decreases response to substance
EXP
ISO
Amiodarone affects the expression of CYP2B3 mRNA
Amiodarone results in increased expression of CYP2B10 mRNA
CYP2B6 protein results in decreased susceptibility to Amiodarone
CTD PMID:19483382 PMID:24535564 PMID:26477383 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression
decreases response to substance
EXP
ISO
Amiodarone results in decreased expression of CYP2C11 mRNA
CYP2C18 protein results in decreased susceptibility to Amiodarone
CTD PMID:26477383 PMID:32084307 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases response to substance ISO CYP2C19 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
decreases response to substance
multiple interactions
increases metabolic processing
ISO Amiodarone results in decreased activity of CYP2C8 protein
CYP2C8 protein results in decreased susceptibility to Amiodarone
torsemide inhibits the reaction [Amiodarone results in decreased activity of CYP2C8 protein]
CYP2C8 protein results in increased metabolism of Amiodarone
CTD PMID:15304522 PMID:15716363 PMID:26477383
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Amiodarone affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression
multiple interactions
increases expression
decreases activity
EXP
ISO
Amiodarone affects the expression of CYP2D4 mRNA
CYP2D6 gene polymorphism affects the reaction [Amiodarone results in increased abundance of Metoprolol]
Amiodarone results in increased expression of CYP2D6 mRNA
Amiodarone results in decreased activity of CYP2D6 protein
CTD PMID:15541258 PMID:16449812 PMID:19483382 PMID:19774075 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases response to substance ISO CYP2E1 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Amiodarone affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of CYP2J2 mRNA
Amiodarone affects the expression of CYP2J4 mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 increases expression ISO Amiodarone results in increased expression of CYP2R1 mRNA CTD PMID:19774075 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Amiodarone affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 decreases expression ISO Amiodarone results in decreased expression of CYP2U1 mRNA CTD PMID:24535564 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882
JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO Amiodarone results in decreased expression of CYP39A1 mRNA CTD PMID:24535564 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
increases degradation
decreases activity
multiple interactions
increases metabolic processing
increases response to substance
decreases ethylation
EXP
ISO
Amiodarone results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in increased degradation of Amiodarone
Amiodarone results in decreased activity of CYP3A4 protein
[Amiodarone co-treated with Benzoic Acid co-treated with cyproconazole co-treated with flusilazole co-treated with enilconazole co-treated with prochloraz co-treated with propiconazole co-treated with tebuconazole] results in increased expression of CYP3A4 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of CXCL8 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of TNF protein; [CYP3A4 protein results in increased metabolism of Amiodarone] which results in increased abundance of mono-N-desethylamiodarone; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Amiodarone]
CYP3A4 protein results in increased susceptibility to Amiodarone
CYP3A4 protein results in decreased ethylation of Amiodarone
CTD PMID:7905403 PMID:8445979 PMID:15304522 PMID:15869686 PMID:16449812 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression
increases expression
EXP Amiodarone affects the expression of CYP3A23-3A1 mRNA
Amiodarone results in increased expression of CYP3A23-3A1 mRNA
CTD PMID:18355885 PMID:19483382 PMID:32084307 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression
decreases response to substance
EXP
ISO
Amiodarone affects the expression of CYP3A9 mRNA
CYP3A5 protein results in decreased susceptibility to Amiodarone
CTD PMID:19483382 PMID:26477383 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Amiodarone results in increased expression of CYP4A1 mRNA CTD PMID:12883083 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Amiodarone affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 affects expression EXP Amiodarone affects the expression of CYP4F2 mRNA CTD PMID:18355885 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Amiodarone affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
increases expression
EXP Amiodarone results in decreased expression of CYP7A1 mRNA
Amiodarone results in increased expression of CYP7A1 mRNA
CTD PMID:19224547 PMID:22291062 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of CYP7B1 mRNA CTD PMID:24535564 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO Amiodarone results in decreased expression of DACT1 mRNA CTD PMID:24535564 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906
JBrowse link
G Dapk2 death-associated protein kinase 2 increases expression ISO Amiodarone results in increased expression of DAPK2 mRNA CTD PMID:19774075 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
JBrowse link
G Dbi diazepam binding inhibitor affects expression EXP Amiodarone affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Dbn1 drebrin 1 increases expression ISO Amiodarone results in increased expression of DBN1 mRNA CTD PMID:19774075 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
JBrowse link
G Dbndd1 dysbindin domain containing 1 increases expression ISO Amiodarone results in increased expression of DBNDD1 mRNA CTD PMID:19774075 NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Amiodarone affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Amiodarone affects the expression of DCAF8 mRNA CTD PMID:18355885 NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726
JBrowse link
G Dcst2 DC-STAMP domain containing 2 increases expression ISO Amiodarone results in increased expression of DCST2 mRNA CTD PMID:19774075 NCBI chr 2:174,781,806...174,795,834
Ensembl chr 2:174,781,902...174,795,832
JBrowse link
G Dctn1 dynactin subunit 1 increases expression ISO Amiodarone results in increased expression of DCTN1 mRNA CTD PMID:19774075 NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Amiodarone affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Ddc dopa decarboxylase increases expression ISO Amiodarone results in increased expression of DDC mRNA CTD PMID:24489787 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
decreases response to substance
multiple interactions
ISO [Amiodarone results in increased expression of DDIT3 mRNA] which results in increased expression of TNFRSF10B mRNA; [Amiodarone results in increased expression of DDIT3 protein] which results in increased expression of TNFRSF10B protein; Amiodarone results in increased expression of DDIT3 mRNA; Amiodarone results in increased expression of DDIT3 protein
DDIT3 gene mutant form results in decreased susceptibility to Amiodarone
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; Amiodarone results in increased expression of and affects the localization of DDIT3 protein; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA]
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 protein]; DDIT3 mutant form inhibits the reaction [Amiodarone results in increased expression of TNFRSF10B]; Egtazic Acid inhibits the reaction [Amiodarone results in increased expression of DDIT3]
CTD PMID:19774075 PMID:21292685 PMID:25295624 PMID:28962527 PMID:32651653 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Amiodarone results in increased expression of DDIT4 mRNA CTD PMID:19774075 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO Amiodarone results in increased expression of DDX17 mRNA CTD PMID:19774075 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193
JBrowse link
G Ddx31 DEAD-box helicase 31 increases expression ISO Amiodarone results in increased expression of DDX31 mRNA CTD PMID:19774075 NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873
JBrowse link
G Ddx39a DExD-box helicase 39A increases expression ISO Amiodarone results in increased expression of DDX39A mRNA CTD PMID:19774075 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
JBrowse link
G Ddx49 DEAD-box helicase 49 increases expression ISO Amiodarone results in increased expression of DDX49 mRNA CTD PMID:19774075 NCBI chr16:19,125,388...19,133,042
Ensembl chr16:19,125,384...19,133,616
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Amiodarone affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dedd death effector domain-containing increases expression ISO Amiodarone results in increased expression of DEDD mRNA CTD PMID:19774075 NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332
JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO Amiodarone results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
JBrowse link
G Deptor DEP domain containing MTOR-interacting protein increases expression ISO Amiodarone results in increased expression of DEPTOR mRNA CTD PMID:19774075 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
JBrowse link
G Dexi Dexi homolog affects expression EXP Amiodarone affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of DGAT1 mRNA
Amiodarone results in increased expression of DGAT1 mRNA
CTD PMID:19483382 PMID:32651653 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO Amiodarone results in decreased expression of DGAT2 mRNA CTD PMID:28962527 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Amiodarone affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP Amiodarone results in increased expression of DHCR7 mRNA CTD PMID:22291062 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Amiodarone results in increased expression of DHRS2 mRNA CTD PMID:19774075 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Amiodarone affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Amiodarone affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Amiodarone affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
JBrowse link
G Dhx57 DExH-box helicase 57 increases expression ISO Amiodarone results in increased expression of DHX57 mRNA CTD PMID:19774075 NCBI chr 6:14,725,305...14,776,321
Ensembl chr 6:14,725,303...14,776,321
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity EXP
ISO
Amiodarone results in decreased activity of DIO1 protein CTD PMID:12538616 PMID:16131326 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO Amiodarone results in increased expression of DLG4 mRNA CTD PMID:19774075 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 increases expression ISO Amiodarone results in increased expression of DLK2 mRNA CTD PMID:19774075 NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Amiodarone affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
JBrowse link
G Dnaaf3 dynein, axonemal, assembly factor 3 increases expression ISO Amiodarone results in increased expression of DNAAF3 mRNA CTD PMID:19774075 NCBI chr 1:69,291,300...69,299,365
Ensembl chr 1:69,291,454...69,299,344
JBrowse link
G Dnah7 dynein, axonemal, heavy chain 7 increases expression ISO Amiodarone results in increased expression of DNAH7 mRNA CTD PMID:19774075 NCBI chr 9:54,960,235...55,266,529
Ensembl chr 9:54,960,440...55,262,297
JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Amiodarone results in decreased expression of DNAJB11 mRNA CTD PMID:24535564 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 increases expression ISO Amiodarone results in increased expression of DNAJB12 mRNA CTD PMID:19774075 NCBI chr20:27,828,216...27,846,428
Ensembl chr20:27,828,235...27,846,427
JBrowse link
G Dnajb7 DnaJ heat shock protein family (Hsp40) member B7 increases expression ISO Amiodarone results in increased expression of DNAJB7 mRNA CTD PMID:19774075 NCBI chr 7:112,932,736...112,934,050
Ensembl chr 7:112,932,616...112,945,537
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression
multiple interactions
ISO Amiodarone results in increased expression of DNAJB9 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]
Amiodarone results in increased expression of DNAJB9 mRNA; Amiodarone results in increased expression of DNAJB9 protein
CTD PMID:19774075 PMID:28962527 PMID:34259586 PMID:36586010 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression
increases expression
multiple interactions
EXP
ISO
Amiodarone affects the expression of DNAJC3 mRNA
Amiodarone results in increased expression of DNAJC3 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJC3 mRNA]
CTD PMID:19483382 PMID:28962527 PMID:34259586 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression ISO Amiodarone results in increased expression of DNASE1 mRNA CTD PMID:19774075 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869
JBrowse link
G Dock5 dedicator of cytokinesis 5 increases expression ISO Amiodarone results in increased expression of DOCK5 mRNA CTD PMID:19774075 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649
JBrowse link
G Dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory increases expression ISO Amiodarone results in increased expression of DPM2 mRNA CTD PMID:19774075 NCBI chr 3:15,855,952...15,858,867
Ensembl chr 3:15,856,182...15,869,165
Ensembl chr 3:15,856,182...15,869,165
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Amiodarone affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Amiodarone affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Drc7 dynein regulatory complex subunit 7 increases expression ISO Amiodarone results in increased expression of DRC7 mRNA CTD PMID:19774075 NCBI chr19:9,943,452...9,961,266
Ensembl chr19:9,943,456...9,961,163
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Amiodarone results in increased expression of DUSP1 mRNA CTD PMID:19774075 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Amiodarone results in increased expression of DUSP10 mRNA CTD PMID:19774075 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dut deoxyuridine triphosphatase increases expression ISO Amiodarone results in increased expression of DUT mRNA CTD PMID:19774075 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771
JBrowse link
G Eaf2 ELL associated factor 2 increases expression ISO Amiodarone results in increased expression of EAF2 mRNA CTD PMID:19774075 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Amiodarone affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression EXP Amiodarone results in increased expression of EBP mRNA CTD PMID:22291062 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826
JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO Amiodarone results in increased expression of ECH1 mRNA CTD PMID:24535564 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Amiodarone affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Amiodarone affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Amiodarone affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
JBrowse link
G Ecpas Ecm29 proteasome adaptor and scaffold decreases expression EXP Amiodarone results in decreased expression of ECPAS mRNA CTD PMID:17991464 NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860
JBrowse link
G Eed embryonic ectoderm development increases expression ISO Amiodarone results in increased expression of EED mRNA CTD PMID:19774075 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Amiodarone affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO Amiodarone results in increased expression of EEPD1 mRNA CTD PMID:19774075 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340
JBrowse link
G Efcab5 EF-hand calcium binding domain 5 increases expression ISO Amiodarone results in increased expression of EFCAB5 mRNA CTD PMID:19774075 NCBI chr10:61,926,419...62,042,745
Ensembl chr10:61,926,953...62,042,749
JBrowse link
G Efcc1 EF-hand and coiled-coil domain containing 1 increases expression ISO Amiodarone results in increased expression of EFCC1 mRNA CTD PMID:19774075 NCBI chr 4:120,188,202...120,223,464
Ensembl chr 4:120,188,470...120,217,516
JBrowse link
G Egf epidermal growth factor multiple interactions ISO Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]] CTD PMID:26515726 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
G Egfl6 EGF-like-domain, multiple 6 increases expression ISO Amiodarone results in increased expression of EGFL6 mRNA CTD PMID:19774075 NCBI chr  X:27,884,087...27,942,044
Ensembl chr  X:27,884,125...27,942,044
JBrowse link
G Egfr epidermal growth factor receptor decreases expression
decreases phosphorylation
multiple interactions
ISO Amiodarone results in decreased expression of EGFR mRNA
Amiodarone results in decreased phosphorylation of EGFR protein
Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein]
Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]
CTD PMID:24535564 PMID:26515726 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Egr1 early growth response 1 increases expression ISO Amiodarone results in increased expression of EGR1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 increases expression ISO Amiodarone results in increased expression of EGR2 mRNA CTD PMID:19774075 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression
decreases expression
increases expression
EXP
ISO
Amiodarone affects the expression of EHHADH mRNA
Amiodarone results in decreased expression of EHHADH mRNA
Amiodarone results in increased expression of EHHADH mRNA
CTD PMID:15265979 PMID:19483382 PMID:24489787 PMID:24535564 PMID:27089845 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 increases expression ISO Amiodarone results in increased expression of EHMT1 mRNA CTD PMID:19774075 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO Amiodarone results in increased phosphorylation of EIF2A protein CTD PMID:21292685 PMID:28962527 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Amiodarone results in increased expression of EIF2AK3 mRNA CTD PMID:19774075 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
ISO Amiodarone results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased phosphorylation of EIF2S1 protein]
CTD PMID:25295624 PMID:32651653 PMID:34259586 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Amiodarone affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B affects expression EXP Amiodarone affects the expression of EIF4B mRNA CTD PMID:18355885 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
decreases phosphorylation
affects expression
ISO
EXP
Amiodarone inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
Amiodarone results in decreased phosphorylation of EIF4EBP1 protein
Amiodarone affects the expression of EIF4EBP1 mRNA
CTD PMID:19483382 PMID:19771169 PMID:23912912 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Amiodarone affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression ISO Amiodarone results in increased expression of EIF5 mRNA CTD PMID:19774075 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656
JBrowse link
G Elmo3 engulfment and cell motility 3 increases expression ISO Amiodarone results in increased expression of ELMO3 mRNA CTD PMID:19774075 NCBI chr19:33,181,952...33,186,399
Ensembl chr19:33,182,036...33,186,410
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression
decreases expression
ISO Amiodarone results in increased expression of ELOVL6 mRNA
Amiodarone results in decreased expression of ELOVL6 mRNA; Amiodarone results in decreased expression of ELOVL6 protein
CTD PMID:24489787 PMID:29248575 PMID:34259586 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 increases expression ISO Amiodarone results in increased expression of ELP1 mRNA CTD PMID:19774075 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Amiodarone affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Enho energy homeostasis associated decreases expression ISO Amiodarone results in decreased expression of ENHO mRNA CTD PMID:24535564 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777
JBrowse link
G Eno1 enolase 1 affects expression EXP Amiodarone affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Amiodarone affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Amiodarone affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 increases expression ISO Amiodarone results in increased expression of ENPP7 mRNA CTD PMID:19774075 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589
JBrowse link
G Epc1 enhancer of polycomb homolog 1 increases expression ISO Amiodarone results in increased expression of EPC1 mRNA CTD PMID:19774075 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425
JBrowse link
G Epc2 enhancer of polycomb homolog 2 increases expression ISO Amiodarone results in increased expression of EPC2 mRNA CTD PMID:19774075 NCBI chr 3:33,867,219...33,967,908
Ensembl chr 3:33,867,219...33,967,150
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Amiodarone affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression EXP Amiodarone affects the expression of EPHX1 mRNA CTD PMID:18355885 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 increases expression ISO Amiodarone results in increased expression of ERI2 mRNA CTD PMID:19774075 NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665
JBrowse link
G Ermn ermin increases expression ISO Amiodarone results in increased expression of ERMN mRNA CTD PMID:19774075 NCBI chr 3:42,628,160...42,633,816
Ensembl chr 3:42,626,309...42,633,744
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO Amiodarone results in increased phosphorylation of ERN1 protein CTD PMID:28962527 PMID:32651653 PMID:34259586 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta decreases expression ISO Amiodarone results in decreased expression of ERO1B mRNA CTD PMID:24535564 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Amiodarone affects the expression of ERP29 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Esd esterase D affects expression EXP Amiodarone affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Amiodarone affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase increases expression ISO Amiodarone results in increased expression of ETFDH mRNA CTD PMID:24489787 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745
JBrowse link
G Exo1 exonuclease 1 increases expression ISO Amiodarone results in increased expression of EXO1 mRNA CTD PMID:19774075 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G F11 coagulation factor XI decreases expression ISO Amiodarone results in decreased expression of F11 mRNA CTD PMID:24535564 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437
JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein] CTD PMID:18974383 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases activity
ISO Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 protein]
Amiodarone results in decreased activity of F3 protein
CTD PMID:18974383 PMID:23305835 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Amiodarone affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
decreases expression
ISO Amiodarone results in increased expression of FABP1 mRNA
Amiodarone results in decreased expression of FABP1 mRNA
CTD PMID:15342952 PMID:17567588 PMID:28962527 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Amiodarone results in increased expression of FABP4 mRNA CTD PMID:34259586 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads1 fatty acid desaturase 1 increases expression EXP Amiodarone results in increased expression of FADS1 mRNA CTD PMID:19224547 PMID:22291062 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions
affects expression
increases expression
ISO
EXP
[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; FADS2 protein affects the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]
Amiodarone affects the expression of FADS2 mRNA
CTD PMID:19483382 PMID:21123845 PMID:29248575 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fam81a family with sequence similarity 81, member A increases expression ISO Amiodarone results in increased expression of FAM81A mRNA CTD PMID:19774075 NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875
JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Amiodarone results in increased expression of FAM89A mRNA CTD PMID:19774075 NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631
JBrowse link
G Fanca FA complementation group A increases expression ISO Amiodarone results in increased expression of FANCA mRNA CTD PMID:19774075 NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527
JBrowse link
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 increases expression ISO Amiodarone results in increased expression of FARP2 mRNA CTD PMID:19774075 NCBI chr 9:94,053,650...94,161,982
Ensembl chr 9:94,053,726...94,162,212
JBrowse link
G Fasn fatty acid synthase increases expression
decreases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of FASN mRNA
Amiodarone results in decreased expression of FASN mRNA; Amiodarone results in decreased expression of FASN protein
Amiodarone affects the expression of FASN mRNA
CTD PMID:22291062 PMID:24489787 PMID:29248575 PMID:32084307 PMID:34259586 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Amiodarone affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fbxo16 F-box protein 16 increases expression ISO Amiodarone results in increased expression of FBXO16 mRNA CTD PMID:19774075 NCBI chr15:39,492,268...39,541,493
Ensembl chr15:39,492,377...39,541,480
JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Amiodarone results in increased expression of FBXO32 mRNA CTD PMID:19774075 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Amiodarone results in increased expression of FCGR2B mRNA CTD PMID:25580480 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fcrl2 Fc receptor-like 2 increases expression ISO Amiodarone results in increased expression of FCRL2 mRNA CTD PMID:19774075 NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression
increases expression
EXP Amiodarone affects the expression of FDFT1 mRNA
Amiodarone results in increased expression of FDFT1 mRNA
CTD PMID:19483382 PMID:22291062 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression
increases expression
EXP Amiodarone affects the expression of FDPS mRNA
Amiodarone results in increased expression of FDPS mRNA
CTD PMID:19483382 PMID:22291062 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Amiodarone affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849
JBrowse link
G Ffar3 free fatty acid receptor 3 increases expression ISO Amiodarone results in increased expression of FFAR3 mRNA CTD PMID:19774075 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 increases expression ISO Amiodarone results in increased expression of FGD4 mRNA CTD PMID:19774075 NCBI chr11:84,399,989...84,551,013
Ensembl chr11:84,399,816...84,546,972
JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression ISO Amiodarone results in increased expression of FGD5 mRNA CTD PMID:19774075 NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Amiodarone results in increased expression of FGF21 mRNA CTD PMID:24489787 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression EXP Amiodarone results in increased expression of FGF7 protein CTD PMID:32909452 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
JBrowse link
G Fgfr1op2 FGFR1 oncogene partner 2 increases expression ISO Amiodarone results in increased expression of FGFR1OP2 mRNA CTD PMID:19774075 NCBI chr 4:179,491,602...179,512,630
Ensembl chr 4:179,491,599...179,512,630
JBrowse link
G Fibcd1 fibrinogen C domain containing 1 increases expression ISO Amiodarone results in increased expression of FIBCD1 mRNA CTD PMID:19774075 NCBI chr 3:15,092,682...15,126,371
Ensembl chr 3:15,092,681...15,126,399
JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Amiodarone results in increased expression of FKBP10 mRNA CTD PMID:19774075 NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330
JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 decreases expression ISO Amiodarone results in decreased expression of FKBP11 mRNA CTD PMID:24535564 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
JBrowse link
G Flcn folliculin increases expression ISO Amiodarone results in increased expression of FLCN mRNA CTD PMID:19774075 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Amiodarone affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Amiodarone results in increased expression of FNDC4 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
ISO Amiodarone results in increased expression of FOS mRNA
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]
CTD PMID:17214612 PMID:19774075 PMID:36586010 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Amiodarone results in increased expression of FOSB mRNA CTD PMID:19774075 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO Amiodarone results in decreased expression of FOXA1 mRNA CTD PMID:27089845 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa3 forkhead box A3 decreases expression EXP
ISO
Amiodarone results in decreased expression of FOXA3 mRNA CTD PMID:17991464 PMID:24535564 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Amiodarone results in increased expression of FOXP3 mRNA CTD PMID:19774075 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression ISO Amiodarone results in increased expression of FRAS1 mRNA CTD PMID:19774075 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726
JBrowse link
G Frmd3 FERM domain containing 3 increases expression ISO Amiodarone results in increased expression of FRMD3 mRNA CTD PMID:19774075 NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091
JBrowse link
G Frmd5 FERM domain containing 5 increases expression ISO Amiodarone results in increased expression of FRMD5 mRNA CTD PMID:19774075 NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Amiodarone results in increased expression of FTL mRNA CTD PMID:36586010 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725
JBrowse link
G Fundc2 FUN14 domain containing 2 increases expression ISO Amiodarone results in increased expression of FUNDC2 mRNA CTD PMID:19774075 NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345
JBrowse link
G Fut4 fucosyltransferase 4 decreases expression EXP Amiodarone results in decreased expression of FUT4 mRNA CTD PMID:17991464 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
JBrowse link
G Fuz fuzzy planar cell polarity protein increases expression ISO Amiodarone results in increased expression of FUZ mRNA CTD PMID:19774075 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530
JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 increases expression ISO Amiodarone results in increased expression of FXYD1 mRNA CTD PMID:19774075 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression EXP
ISO
Amiodarone results in increased expression of G6PDX mRNA
Amiodarone results in increased expression of G6PD mRNA
CTD PMID:19224547 PMID:19774075 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Amiodarone results in increased expression of GADD45A mRNA CTD PMID:19774075 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Amiodarone results in increased expression of GADD45G mRNA CTD PMID:19774075 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression EXP Amiodarone results in increased expression of GAL mRNA CTD PMID:25580480 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
JBrowse link
G Gal3st3 galactose-3-O-sulfotransferase 3 increases expression ISO Amiodarone results in increased expression of GAL3ST3 mRNA CTD PMID:19774075 NCBI chr 1:202,593,635...202,603,446
Ensembl chr 1:202,593,692...202,603,445
JBrowse link
G Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 increases expression ISO Amiodarone results in increased expression of GALNT17 mRNA CTD PMID:19774075 NCBI chr12:25,323,230...25,781,897
Ensembl chr12:25,322,701...25,781,290
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Amiodarone affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Amiodarone affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gata2 GATA binding protein 2 decreases expression EXP Amiodarone results in decreased expression of GATA2 mRNA CTD PMID:17991464 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gatb glutamyl-tRNA amidotransferase subunit B increases expression ISO Amiodarone results in increased expression of GATB mRNA CTD PMID:24535564 NCBI chr 2:170,930,547...171,017,133
Ensembl chr 2:170,930,542...171,016,695
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Amiodarone affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Amiodarone results in increased expression of GBP2 mRNA CTD PMID:19774075 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Amiodarone affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
JBrowse link
G Gckr glucokinase regulator affects expression EXP Amiodarone affects the expression of GCKR mRNA CTD PMID:18355885 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Amiodarone results in increased expression of GCLM mRNA CTD PMID:36586010 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Amiodarone results in increased expression of GDF15 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gdf5 growth differentiation factor 5 increases expression ISO Amiodarone results in increased expression of GDF5 mRNA CTD PMID:19774075 NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Amiodarone results in increased expression of GDPD3 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Amiodarone results in increased expression of GEM mRNA CTD PMID:19774075 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP Amiodarone results in increased expression of GFAP mRNA CTD PMID:22954530 PMID:25659768 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfod1 Gfo/Idh/MocA-like oxidoreductase domain containing 1 increases expression ISO Amiodarone results in increased expression of GFOD1 mRNA CTD PMID:19774075 NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Amiodarone affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA] CTD PMID:2910914 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Gins1 GINS complex subunit 1 increases expression ISO Amiodarone results in increased expression of GINS1 mRNA CTD PMID:19774075 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO Amiodarone results in decreased expression of GJA1 mRNA CTD PMID:15520326 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression ISO Amiodarone results in increased expression of GJA5 mRNA CTD PMID:19774075 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Amiodarone affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gjd3 gap junction protein, delta 3 increases expression ISO Amiodarone results in increased expression of GJD3 mRNA CTD PMID:19774075 NCBI chr10:83,933,694...83,935,759
Ensembl chr10:83,934,135...83,934,971
JBrowse link
G Gk5 glycerol kinase 5 increases expression ISO Amiodarone results in increased expression of GK5 mRNA CTD PMID:19774075 NCBI chr 8:96,682,469...96,751,407
Ensembl chr 8:96,682,470...96,749,166
JBrowse link
G Gkap1 G kinase anchoring protein 1 increases expression ISO Amiodarone results in increased expression of GKAP1 mRNA CTD PMID:19774075 NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679
JBrowse link
G Gls2 glutaminase 2 affects expression EXP Amiodarone affects the expression of GLS2 mRNA CTD PMID:18355885 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426
JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression EXP Amiodarone results in increased expression of GLUD1 protein CTD PMID:16538043 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
JBrowse link
G Gnas GNAS complex locus increases expression ISO Amiodarone results in increased expression of GNAS mRNA CTD PMID:19774075 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262
JBrowse link
G Gnl1 G protein nucleolar 1 decreases expression EXP Amiodarone results in decreased expression of GNL1 mRNA CTD PMID:17991464 NCBI chr20:2,783,130...2,792,115
Ensembl chr20:2,778,985...2,792,115
JBrowse link
G Gnpat glyceronephosphate O-acyltransferase increases expression EXP Amiodarone results in increased expression of GNPAT mRNA CTD PMID:22291062 NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361
JBrowse link
G Gon4l gon-4 like increases expression ISO Amiodarone results in increased expression of GON4L mRNA CTD PMID:19774075 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression EXP Amiodarone affects the expression of GOT2 mRNA CTD PMID:18355885 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Amiodarone results in increased expression of GPAM mRNA CTD PMID:19224547 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Amiodarone results in increased expression of GPAT3 mRNA CTD PMID:24535564 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Amiodarone affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C increases expression ISO Amiodarone results in increased expression of GPRC5C mRNA CTD PMID:19774075 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
multiple interactions
increases activity
ISO
EXP
Amiodarone results in increased expression of GPT protein
1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [Dexamethasone results in increased susceptibility to Amiodarone] which results in increased expression of GPT protein; Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]; gadolinium chloride inhibits the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]
Amiodarone results in increased activity of GPT protein
CTD PMID:8522712 PMID:22291062 PMID:24685772 PMID:25900201 PMID:32084307 More... NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Amiodarone results in increased expression of GPT2 mRNA CTD PMID:24489787 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression
multiple interactions
decreases expression
EXP
ISO
Amiodarone affects the expression of GPX1 mRNA
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]
CTD PMID:19483382 PMID:34434487 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Amiodarone affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grb14 growth factor receptor bound protein 14 affects expression EXP Amiodarone affects the expression of GRB14 mRNA CTD PMID:18355885 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Amiodarone affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases expression ISO Amiodarone results in increased expression of GRM2 mRNA CTD PMID:19774075 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Amiodarone affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO Amiodarone results in decreased phosphorylation of GSK3B protein CTD PMID:26515726 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin increases expression EXP Amiodarone results in increased expression of GSN mRNA CTD PMID:17991464 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO Amiodarone results in increased expression of GSTA2 mRNA CTD PMID:36586010 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsto2 glutathione S-transferase omega 2 increases expression ISO Amiodarone results in increased expression of GSTO2 mRNA CTD PMID:19774075 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Amiodarone affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression ISO Amiodarone results in increased expression of GSTZ1 mRNA CTD PMID:19774075 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Amiodarone affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 increases expression ISO Amiodarone results in increased expression of GUCY1A2 mRNA CTD PMID:19774075 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO Amiodarone results in increased expression of GUCY1B1 mRNA CTD PMID:19774075 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Gzma granzyme A affects expression EXP Amiodarone affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G H2aj H2A.J histone increases expression ISO Amiodarone results in increased expression of H2AJ mRNA CTD PMID:19774075 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006
JBrowse link
G H2bc6 H2B clustered histone 6 increases expression ISO Amiodarone results in increased expression of H2BC6 mRNA CTD PMID:19774075 NCBI chr17:41,520,775...41,521,238 JBrowse link
G H3f3b H3.3 histone B affects expression EXP Amiodarone affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Amiodarone affects the expression of HAL mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Amiodarone affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Amiodarone affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Amiodarone affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 increases expression ISO Amiodarone results in increased expression of HCN1 mRNA CTD PMID:19774075 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774
JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 decreases expression EXP Amiodarone results in decreased expression of HCN2 mRNA CTD PMID:17711693 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841
JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 decreases expression EXP Amiodarone results in decreased expression of HCN4 mRNA CTD PMID:17711693 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639
JBrowse link
G Hdc histidine decarboxylase affects expression EXP Amiodarone affects the expression of HDC mRNA CTD PMID:19483382 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hdx highly divergent homeobox increases expression ISO Amiodarone results in increased expression of HDX mRNA CTD PMID:19774075 NCBI chr  X:76,552,539...76,697,177
Ensembl chr  X:76,560,665...76,869,972
JBrowse link
G Helb DNA helicase B increases expression ISO Amiodarone results in increased expression of HELB mRNA CTD PMID:19774075 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Amiodarone results in increased expression of HERPUD1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP Amiodarone results in decreased expression of HES6 mRNA CTD PMID:17991464 NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hexa hexosaminidase subunit alpha increases expression
multiple interactions
ISO Amiodarone results in increased expression of HEXA mRNA
Amiodarone results in increased activity of and results in increased secretion of HEXA protein
CTD PMID:25881747 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013
JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions ISO Amiodarone results in increased activity of and results in increased secretion of HEXB protein CTD PMID:25881747 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223
JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO Amiodarone results in increased expression of HEXIM1 mRNA CTD PMID:19774075 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Amiodarone affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
JBrowse link
G Hgfac HGF activator increases expression ISO Amiodarone results in increased expression of HGFAC mRNA CTD PMID:19774075 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Amiodarone results in decreased expression of HIF1A mRNA CTD PMID:35641671 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hira histone cell cycle regulator increases expression ISO Amiodarone results in increased expression of HIRA mRNA CTD PMID:19774075 NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529
JBrowse link
G Hjv hemojuvelin BMP co-receptor increases expression ISO Amiodarone results in increased expression of HJV mRNA CTD PMID:24535564 NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850
JBrowse link
G Hmgb2 high mobility group box 2 affects expression EXP Amiodarone affects the expression of HMGB2 mRNA CTD PMID:18355885 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Amiodarone results in increased expression of HMGCR mRNA CTD PMID:24489787 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Amiodarone results in increased expression of HMGCS1 mRNA CTD PMID:22291062 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Amiodarone affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
JBrowse link
G Hmgxb4 HMG-box containing 4 increases expression ISO Amiodarone results in increased expression of HMGXB4 mRNA CTD PMID:19774075 NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of HMOX1 mRNA
Amiodarone affects the expression of HMOX1 mRNA
CTD PMID:18020914 PMID:19224547 PMID:19774075 PMID:25659768 PMID:31324950 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO Amiodarone results in increased expression of HNF4A mRNA CTD PMID:24489787 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
JBrowse link
G Hnf4g hepatocyte nuclear factor 4, gamma increases expression ISO Amiodarone results in increased expression of HNF4G mRNA CTD PMID:19774075 NCBI chr 2:97,885,773...98,036,650
Ensembl chr 2:97,887,432...98,036,592
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO Amiodarone results in increased expression of HNRNPA1 mRNA CTD PMID:21163907 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO Amiodarone results in increased expression of HOXB6 mRNA CTD PMID:19774075 NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449
JBrowse link
G Hoxc4 homeo box C4 increases expression ISO Amiodarone results in increased expression of HOXC4 mRNA CTD PMID:19774075 NCBI chr 7:134,135,279...134,173,133
Ensembl chr 7:134,170,591...134,173,133
JBrowse link
G Hpn hepsin increases expression ISO Amiodarone results in increased expression of HPN mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Amiodarone affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Amiodarone affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression ISO Amiodarone results in increased expression of HRK mRNA CTD PMID:19774075 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone increases expression ISO Amiodarone results in increased expression of HSCB mRNA CTD PMID:24535564 NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909
JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO Amiodarone results in increased expression of HSD17B11 mRNA CTD PMID:24535564 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Amiodarone affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Amiodarone affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO Amiodarone results in increased expression of HSPA5 mRNA; Amiodarone results in increased expression of HSPA5 protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 protein]
CTD PMID:25295624 PMID:34259586 PMID:36586010 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Amiodarone results in increased expression of HSPD1 protein CTD PMID:16538043 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Amiodarone results in increased expression of HTATIP2 mRNA CTD PMID:24535564 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Amiodarone affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Htra2 HtrA serine peptidase 2 increases expression ISO Amiodarone results in increased expression of HTRA2 mRNA CTD PMID:24489787 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095
JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Amiodarone results in increased expression of HUS1 mRNA CTD PMID:19774075 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions
ISO Amiodarone results in increased expression of ICAM1 mRNA
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein
CTD PMID:19774075 PMID:22785256 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Amiodarone results in increased expression of ID2 mRNA CTD PMID:23397585 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases expression ISO Amiodarone results in increased expression of IDH2 mRNA CTD PMID:24489787 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
EXP
ISO
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Losartan inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Prednisolone inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Vitamin D inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]
CTD PMID:25073960 PMID:34590760 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Amiodarone affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of IGFALS mRNA
Amiodarone affects the expression of IGFALS mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Amiodarone results in increased expression of IGFBP1 mRNA CTD PMID:27089845 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Amiodarone affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igsf8 immunoglobulin superfamily, member 8 increases expression ISO Amiodarone results in increased expression of IGSF8 mRNA CTD PMID:19774075 NCBI chr13:84,770,348...84,781,534
Ensembl chr13:84,770,279...84,778,576
JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions
ISO Amiodarone results in decreased expression of IL10 mRNA; Amiodarone results in decreased expression of IL10 protein
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]
CTD PMID:34434487 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO Amiodarone results in increased expression of IL10RA mRNA CTD PMID:19774075 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
JBrowse link
G Il18 interleukin 18 multiple interactions ISO Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] CTD PMID:25900201 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions
ISO Amiodarone results in increased expression of IL1A mRNA
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone
CTD PMID:19362101 PMID:19774075 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
ISO
EXP
[Amiodarone co-treated with Dexamethasone] results in decreased expression of IL1B mRNA
Amiodarone results in increased expression of IL1B mRNA; Amiodarone results in increased expression of IL1B protein
ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]
CTD PMID:25580480 PMID:25900201 PMID:34434487 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein] CTD PMID:25073960 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il33 interleukin 33 affects expression EXP Amiodarone affects the expression of IL33 mRNA CTD PMID:18355885 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Il4 interleukin 4 multiple interactions EXP
ISO
[Vitamin D co-treated with Losartan] inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL4 protein]
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]
CTD PMID:25073960 PMID:34590760 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
increases secretion
ISO
EXP
Amiodarone results in increased expression of IL6 mRNA; Amiodarone results in increased expression of IL6 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL6 protein]
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; Prednisolone inhibits the reaction [Amiodarone results in increased secretion of IL6 protein]
CTD PMID:11288978 PMID:19362101 PMID:34434487 PMID:34590760 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Amiodarone affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Inhba inhibin subunit beta A decreases expression ISO Amiodarone results in decreased expression of INHBA mRNA CTD PMID:24535564 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inhbe inhibin subunit beta E affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of INHBE mRNA
Amiodarone results in increased expression of INHBE mRNA
CTD PMID:15342952 PMID:17175557 PMID:17567588 PMID:19483382 PMID:19774075 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Amiodarone results in increased expression of INKA2 mRNA CTD PMID:19774075 NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:193,185,275...193,200,642
JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase increases expression ISO Amiodarone results in increased expression of IPPK mRNA CTD PMID:19774075 NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Amiodarone results in increased expression of IRAK2 mRNA CTD PMID:19774075 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO Amiodarone results in increased expression of IRF1 mRNA CTD PMID:19774075 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Isx intestine-specific homeobox increases expression ISO Amiodarone results in increased expression of ISX mRNA CTD PMID:19774075 NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Amiodarone affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO Amiodarone results in decreased expression of ITGB5 mRNA CTD PMID:23397585 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 increases expression ISO Amiodarone results in increased expression of ITIH2 mRNA CTD PMID:19774075 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Amiodarone affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Ivns1abp influenza virus NS1A binding protein increases expression EXP Amiodarone results in increased expression of IVNS1ABP mRNA CTD PMID:17991464 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701
JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Amiodarone affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 increases expression ISO Amiodarone results in increased expression of JAKMIP3 mRNA CTD PMID:19774075 NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104
JBrowse link
G Jrkl JRK-like increases expression ISO Amiodarone results in increased expression of JRKL mRNA CTD PMID:19774075 NCBI chr 8:10,224,172...10,227,068
Ensembl chr 8:10,224,172...10,227,068
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
increases phosphorylation
EXP
ISO
Amiodarone results in increased expression of JUN mRNA; Amiodarone results in increased expression of JUN protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]
CTD PMID:11597910 PMID:17214612 PMID:25073960 PMID:34590760 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 increases expression ISO Amiodarone results in increased expression of KCNA4 mRNA CTD PMID:15520326 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162
JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases expression ISO
EXP
Amiodarone results in decreased expression of KCNA5 mRNA CTD PMID:8973384 PMID:9302343 PMID:15520326 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression ISO Amiodarone results in increased expression of KCNAB1 mRNA CTD PMID:15520326 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of KCNB1 mRNA CTD PMID:15520326 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Amiodarone results in decreased expression of KCND2 mRNA CTD PMID:15520326 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 increases expression ISO Amiodarone results in increased expression of KCNE3 mRNA CTD PMID:15520326 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 increases expression ISO Amiodarone results in increased expression of KCNE5 mRNA CTD PMID:19774075 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects activity
increases expression
decreases activity
multiple interactions
ISO
EXP
Amiodarone affects the activity of KCNH2 protein
Amiodarone results in increased expression of KCNH2 mRNA
Amiodarone results in decreased activity of KCNH2 protein
Amiodarone binds to and results in decreased activity of KCNH2 protein; Amiodarone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; Amiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]; Potassium inhibits the reaction [Amiodarone results in decreased activity of KCNH2 protein]
CTD PMID:10208308 PMID:11238279 PMID:15272206 PMID:15618689 PMID:15671647 More... NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 increases expression ISO Amiodarone results in increased expression of KCNJ2 mRNA CTD PMID:19774075 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445
JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 increases expression ISO Amiodarone results in increased expression of KCNK1 mRNA CTD PMID:15520326 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724
JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 increases expression ISO Amiodarone results in increased expression of KCNK12 mRNA CTD PMID:19774075 NCBI chr 6:6,740,147...6,790,664
Ensembl chr 6:6,739,991...6,790,661
JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 increases expression ISO Amiodarone results in increased expression of KCNMA1 mRNA CTD PMID:19774075 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198
JBrowse link
G Kctd14 potassium channel tetramerization domain containing 14 increases expression ISO Amiodarone results in increased expression of KCTD14 mRNA CTD PMID:19774075 NCBI chr 1:151,761,688...151,766,693
Ensembl chr 1:151,761,663...151,766,691
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Amiodarone affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Kdr kinase insert domain receptor affects expression EXP Amiodarone affects the expression of KDR mRNA CTD PMID:19483382 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP Amiodarone results in decreased expression of KEAP1 mRNA CTD PMID:17991464 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO Amiodarone results in increased expression of KHDRBS3 mRNA CTD PMID:24535564 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
JBrowse link
G Kif16b kinesin family member 16B increases expression ISO Amiodarone results in increased expression of KIF16B mRNA CTD PMID:19774075 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019
JBrowse link
G Kif17 kinesin family member 17 increases expression ISO Amiodarone results in increased expression of KIF17 mRNA CTD PMID:19774075 NCBI chr 5:150,482,288...150,521,471
Ensembl chr 5:150,481,578...150,519,638
JBrowse link
G Kifc1 kinesin family member C1 increases expression ISO Amiodarone results in increased expression of KIFC1 mRNA CTD PMID:19774075 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Kitlg KIT ligand increases expression ISO Amiodarone results in increased expression of KITLG mRNA CTD PMID:19774075 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
JBrowse link
G Klf10 KLF transcription factor 10 increases expression ISO Amiodarone results in increased expression of KLF10 mRNA CTD PMID:19774075 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klf15 KLF transcription factor 15 increases expression ISO Amiodarone results in increased expression of KLF15 mRNA CTD PMID:19774075 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
JBrowse link
G Klf16 KLF transcription factor 16 increases expression ISO Amiodarone results in increased expression of KLF16 mRNA CTD PMID:19774075 NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317
JBrowse link
G Klf4 KLF transcription factor 4 increases expression ISO Amiodarone results in increased expression of KLF4 mRNA CTD PMID:19774075 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
JBrowse link
G Klhl28 kelch-like family member 28 increases expression ISO Amiodarone results in increased expression of KLHL28 mRNA CTD PMID:19774075 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164
JBrowse link
G Klk14 kallikrein related-peptidase 14 increases expression ISO Amiodarone results in increased expression of KLK14 mRNA CTD PMID:19774075 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240
JBrowse link
G Krt17 keratin 17 increases expression ISO Amiodarone results in increased expression of KRT17 mRNA CTD PMID:19774075 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt23 keratin 23 increases expression ISO Amiodarone results in increased expression of KRT23 mRNA CTD PMID:24535564 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983
JBrowse link
G Krt8 keratin 8 affects expression EXP Amiodarone affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 increases expression ISO Amiodarone results in increased expression of L3MBTL1 mRNA CTD PMID:19774075 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233
JBrowse link
G Lama2 laminin subunit alpha 2 increases expression ISO Amiodarone results in increased expression of LAMA2 mRNA CTD PMID:24489787 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530
JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial increases expression ISO Amiodarone results in increased expression of LARS2 mRNA CTD PMID:24489787 NCBI chr 8:123,010,271...123,106,395
Ensembl chr 8:123,010,293...123,106,395
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression
increases expression
EXP Amiodarone affects the expression of LCAT mRNA
Amiodarone results in increased expression of LCAT mRNA
CTD PMID:19483382 PMID:22291062 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Amiodarone affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
JBrowse link
G Lctl lactase-like increases expression ISO Amiodarone results in increased expression of LCTL mRNA CTD PMID:19774075 NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases expression
ISO
EXP
Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA]
Amiodarone results in decreased expression of LDLR mRNA; Amiodarone results in decreased expression of LDLR protein
Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein]
CTD PMID:8137927 PMID:9071962 PMID:9712728 PMID:9751232 PMID:12538616 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor increases expression ISO Amiodarone results in increased expression of LHCGR mRNA CTD PMID:19774075 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Amiodarone results in increased expression of LIF mRNA CTD PMID:19774075 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component increases expression ISO Amiodarone results in increased expression of LIN7A mRNA CTD PMID:19774075 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550
JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Amiodarone affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions
increases phosphorylation
ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 PMID:34259586 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
JBrowse link
G LOC103689958 olfactory receptor 49-like increases expression ISO Amiodarone results in increased expression of OR6T1 mRNA CTD PMID:19774075 NCBI chr 1:65,911,907...65,913,255
Ensembl chr 1:65,912,105...65,913,079
JBrowse link
G Lox lysyl oxidase affects expression EXP Amiodarone affects the expression of LOX mRNA CTD PMID:18355885 PMID:19483382 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 increases expression ISO Amiodarone results in increased expression of LPCAT3 mRNA CTD PMID:24489787 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880
JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 increases expression EXP Amiodarone results in increased expression of LPGAT1 mRNA CTD PMID:22291062 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333
JBrowse link
G Lpin3 lipin 3 increases expression ISO Amiodarone results in increased expression of LPIN3 mRNA CTD PMID:24489787 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Amiodarone affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
JBrowse link
G Lrp5 LDL receptor related protein 5 increases expression ISO Amiodarone results in increased expression of LRP5 mRNA CTD PMID:19774075 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
JBrowse link
G Lss lanosterol synthase increases expression
affects expression
EXP
ISO
Amiodarone results in increased expression of LSS mRNA
Amiodarone affects the expression of LSS mRNA
CTD PMID:15342952 PMID:17567588 PMID:19224547 PMID:22291062 PMID:24489787 More... NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO Amiodarone results in increased expression of LY6D mRNA CTD PMID:24489787 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733
JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Amiodarone results in increased expression of LYZ mRNA CTD PMID:19774075 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 increases expression ISO Amiodarone results in increased expression of MACROD2 mRNA CTD PMID:19774075 NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492
JBrowse link
G Macroh2a1 macroH2A.1 histone affects expression EXP Amiodarone affects the expression of MACROH2A1 mRNA CTD PMID:18355885 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Amiodarone results in increased expression of MAFF mRNA CTD PMID:36586010 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Amiodarone results in increased expression of MAFG mRNA CTD PMID:19774075 PMID:36586010 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Amiodarone affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
JBrowse link
G Manba mannosidase beta affects expression EXP Amiodarone affects the expression of MANBA mRNA CTD PMID:18355885 NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation
multiple interactions
ISO Amiodarone results in increased lipidation of MAP1LC3B protein
Amiodarone results in increased expression of and results in increased lipidation of MAP1LC3B protein; Amiodarone results in increased lipidation of and results in increased localization of MAP1LC3B protein
CTD PMID:25881747 PMID:32651653 PMID:37661063 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein inhibits the reaction [Amiodarone results in decreased expression of SNAI1 protein] CTD PMID:26515726 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Amiodarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation
EXP
ISO
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]
Amiodarone results in decreased phosphorylation of MAPK1 protein
CTD PMID:26515726 PMID:31071512 PMID:34590760 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
multiple interactions
EXP Amiodarone results in increased phosphorylation of MAPK14 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]
CTD PMID:34590760 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
decreases phosphorylation
multiple interactions
EXP
ISO
Amiodarone results in increased phosphorylation of MAPK3 protein
Amiodarone results in decreased phosphorylation of MAPK3 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]
CTD PMID:26515726 PMID:31071512 PMID:34590760 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation
ISO Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein]
Amiodarone results in increased phosphorylation of MAPK8 protein
CTD PMID:25073960 PMID:34259586 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Masp1 MBL associated serine protease 1 increases expression ISO Amiodarone results in increased expression of MASP1 mRNA CTD PMID:19774075 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Amiodarone affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
JBrowse link
G Mbp myelin basic protein affects expression EXP Amiodarone affects the expression of MBP mRNA CTD PMID:25659768 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Amiodarone results in increased expression of MCAM mRNA CTD PMID:19774075 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571
JBrowse link
G Mcf2 MCF.2 cell line derived transforming sequence increases expression ISO Amiodarone results in increased expression of MCF2 mRNA CTD PMID:19774075 NCBI chr  X:138,414,077...138,514,828
Ensembl chr  X:138,409,256...138,514,446
JBrowse link
G Me1 malic enzyme 1 increases expression
affects expression
EXP Amiodarone results in increased expression of ME1 protein
Amiodarone affects the expression of ME1 mRNA
CTD PMID:16538043 PMID:19483382 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Med11 mediator complex subunit 11 increases expression ISO Amiodarone results in increased expression of MED11 mRNA CTD PMID:19774075 NCBI chr10:55,164,322...55,165,940
Ensembl chr10:55,164,326...55,166,533
JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO Amiodarone results in increased expression of MEF2C mRNA CTD PMID:19774075 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 increases expression
decreases expression
ISO Amiodarone results in increased expression of MFHAS1 mRNA
Amiodarone results in decreased expression of MFHAS1 mRNA
CTD PMID:19774075 PMID:24535564 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743
JBrowse link
G Mfn2 mitofusin 2 increases expression ISO Amiodarone results in increased expression of MFN2 mRNA CTD PMID:24489787 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
JBrowse link
G Mfsd1 major facilitator superfamily domain containing 1 decreases expression EXP Amiodarone results in decreased expression of MFSD1 mRNA CTD PMID:17991464 NCBI chr 2:151,846,130...151,866,168
Ensembl chr 2:151,846,146...151,867,045
JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A increases expression ISO Amiodarone results in increased expression of MGAT4A mRNA CTD PMID:19774075 NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Amiodarone results in increased expression of MGST1 mRNA CTD PMID:19774075 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO Amiodarone results in increased expression of MGST3 mRNA CTD PMID:24535564 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Micall2 MICAL-like 2 increases expression ISO Amiodarone results in increased expression of MICALL2 mRNA CTD PMID:19774075 NCBI chr12:14,899,188...14,927,949
Ensembl chr12:14,899,157...14,927,946
JBrowse link
G Mid2 midline 2 increases expression ISO Amiodarone results in increased expression of MID2 mRNA CTD PMID:19774075 NCBI chr  X:104,354,692...104,456,757
Ensembl chr  X:104,355,316...104,453,473
JBrowse link
G Mipep mitochondrial intermediate peptidase increases expression ISO Amiodarone results in increased expression of MIPEP mRNA CTD PMID:24489787 NCBI chr15:34,926,198...35,051,722
Ensembl chr15:34,926,207...35,051,727
JBrowse link
G Mir16 microRNA 16 decreases expression EXP Amiodarone results in decreased expression of MIR16 mRNA CTD PMID:17991464 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir224 microRNA 224 decreases expression ISO
EXP
Amiodarone decreased expression of miR224 in a human hepatoma cell line
Amiodarone decreased expression of miR224 in rat liver tumors
RGD PMID:23913306 PMID:23913306 RGD:18182923, RGD:18182923 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Amiodarone results in increased expression of MITF mRNA CTD PMID:19774075 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Mlx MAX dimerization protein MLX affects expression EXP Amiodarone affects the expression of MLX mRNA CTD PMID:18355885 NCBI chr10:86,019,216...86,024,326
Ensembl chr10:86,019,588...86,032,350
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression ISO Amiodarone results in decreased expression of MLXIPL mRNA CTD PMID:28962527 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression ISO Amiodarone results in increased expression of MLYCD mRNA CTD PMID:24489787 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression EXP Amiodarone affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
JBrowse link
G Morn5 MORN repeat containing 5 increases expression ISO Amiodarone results in increased expression of MORN5 mRNA CTD PMID:19774075 NCBI chr 3:19,402,221...19,430,075
Ensembl chr 3:19,401,801...19,430,083
JBrowse link
G Mpi mannose phosphate isomerase increases expression ISO Amiodarone results in increased expression of MPI mRNA CTD PMID:19774075 NCBI chr 8:57,947,883...57,956,205
Ensembl chr 8:57,947,893...57,956,150
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Amiodarone promotes the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:18087811 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mro maestro affects expression EXP Amiodarone affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044
JBrowse link
G Mrpl10 mitochondrial ribosomal protein L10 increases expression ISO Amiodarone results in increased expression of MRPL10 mRNA CTD PMID:19774075 NCBI chr10:82,026,031...82,034,451
Ensembl chr10:82,026,031...82,034,443
JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression EXP Amiodarone affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr 9:14,333,233...14,337,006
Ensembl chr 9:14,333,234...14,337,040
JBrowse link
G mrpl9 mitochondrial ribosomal protein L9 affects expression EXP Amiodarone affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095
JBrowse link
G Mrps12 mitochondrial ribosomal protein S12 increases expression ISO Amiodarone results in increased expression of MRPS12 mRNA CTD PMID:24489787 NCBI chr 1:84,025,896...84,028,896
Ensembl chr 1:84,025,899...84,028,780
JBrowse link
G Mrps18b mitochondrial ribosomal protein S18B affects expression EXP Amiodarone affects the expression of MRPS18B mRNA CTD PMID:18355885 NCBI chr20:2,838,174...2,844,260
Ensembl chr20:2,838,030...2,844,260
JBrowse link
G Ms4a14 membrane spanning 4-domains A14 increases expression ISO Amiodarone results in increased expression of MS4A14 mRNA CTD PMID:19774075 NCBI chr 1:207,949,423...207,964,937
Ensembl chr 1:207,949,426...207,964,937
JBrowse link
G Msmo1 methylsterol monooxygenase 1 affects expression
increases expression
EXP Amiodarone affects the expression of MSMO1 mRNA
Amiodarone results in increased expression of MSMO1 mRNA
CTD PMID:18355885 PMID:22291062 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mt-co3 mitochondrially encoded cytochrome c oxidase III increases expression EXP Amiodarone results in increased expression of COX3 mRNA CTD PMID:12883083 NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
JBrowse link
G Mt1-ps3 metallothionein 1, pseudogene 3 increases expression ISO Amiodarone results in increased expression of MT1E mRNA CTD PMID:36586010 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Amiodarone results in increased expression of MT2A mRNA CTD PMID:36586010 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 decreases expression ISO Amiodarone results in decreased expression of MTF1 mRNA CTD PMID:35641671 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
JBrowse link
G Mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase increases expression ISO Amiodarone results in increased expression of MTHFD2 mRNA CTD PMID:36586010 NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO Amiodarone inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO Amiodarone results in decreased expression of MTTP mRNA CTD PMID:27089845 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Mug2 murinoglobulin 2 affects expression EXP Amiodarone affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475
JBrowse link
G Mvd mevalonate diphosphate decarboxylase increases expression EXP Amiodarone results in increased expression of MVD mRNA CTD PMID:22291062 NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Amiodarone results in increased expression of MXD1 mRNA CTD PMID:19774075 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
JBrowse link
G Myadm myeloid-associated differentiation marker affects expression EXP Amiodarone affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression EXP Amiodarone results in decreased expression of MYC mRNA CTD PMID:17202758 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycbp2 MYC binding protein 2 affects expression EXP Amiodarone affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
JBrowse link
G Myef2 myelin expression factor 2 increases expression ISO Amiodarone results in increased expression of MYEF2 mRNA CTD PMID:19774075 NCBI chr 3:112,338,241...112,374,122
Ensembl chr 3:112,338,241...112,374,181
JBrowse link
G Myh11 myosin heavy chain 11 increases expression ISO Amiodarone results in increased expression of MYH11 mRNA CTD PMID:19774075 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Amiodarone results in decreased expression of MYH6 mRNA CTD PMID:17535870 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Amiodarone results in increased expression of MYH7 mRNA CTD PMID:17535870 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myl4 myosin, light chain 4 increases expression ISO Amiodarone results in increased expression of MYL4 mRNA CTD PMID:19774075 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Mylk2 myosin light chain kinase 2 increases expression ISO Amiodarone results in increased expression of MYLK2 mRNA CTD PMID:19774075 NCBI chr 3:141,376,450...141,388,357
Ensembl chr 3:141,376,691...141,387,728
JBrowse link
G Myo1d myosin ID affects expression EXP Amiodarone affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
JBrowse link
G Myo3a myosin IIIA increases expression ISO Amiodarone results in increased expression of MYO3A mRNA CTD PMID:19774075 NCBI chr17:84,543,465...84,759,562
Ensembl chr17:84,543,552...84,759,042
JBrowse link
G N4bp3 Nedd4 binding protein 3 increases expression ISO Amiodarone results in increased expression of N4BP3 mRNA CTD PMID:19774075 NCBI chr10:35,898,031...35,906,704
Ensembl chr10:35,899,096...35,907,001
JBrowse link
G Naa16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit increases expression ISO Amiodarone results in increased expression of NAA16 mRNA CTD PMID:19774075 NCBI chr15:54,711,620...54,770,915
Ensembl chr15:54,711,621...54,770,896
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression EXP Amiodarone affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494
JBrowse link
G Nanos1 nanos C2HC-type zinc finger 1 increases expression ISO Amiodarone results in increased expression of NANOS1 mRNA CTD PMID:19774075 NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression EXP Amiodarone affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Napsa napsin A aspartic peptidase decreases expression EXP Amiodarone results in decreased expression of NAPSA mRNA CTD PMID:17991464 NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094
JBrowse link
G Nat8 N-acetyltransferase 8 affects expression EXP Amiodarone affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
JBrowse link
G Ndrg2 NDRG family member 2 affects expression
decreases expression
EXP Amiodarone affects the expression of NDRG2 mRNA
Amiodarone results in decreased expression of NDRG2 protein
CTD PMID:16538043 PMID:19483382 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 increases expression ISO Amiodarone results in increased expression of NDUFC2 mRNA CTD PMID:24489787 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189
JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 increases expression ISO Amiodarone results in increased expression of NDUFS1 mRNA CTD PMID:24489787 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 affects expression EXP Amiodarone affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
Ensembl chr14:135,974,034...135,979,603
Ensembl chr 2:135,974,034...135,979,603
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 affects expression EXP Amiodarone affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
Ensembl chr13:9,612,431...9,623,074
JBrowse link
G Nefh neurofilament heavy chain decreases expression EXP Amiodarone results in decreased expression of NEFH mRNA CTD PMID:25659768 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nek8 NIMA-related kinase 8 increases expression ISO Amiodarone results in increased expression of NEK8 mRNA CTD PMID:19774075 NCBI chr10:63,060,868...63,073,546
Ensembl chr10:63,061,253...63,072,416
JBrowse link
G Neu2 neuraminidase 2 affects expression EXP Amiodarone affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor increases expression ISO Amiodarone results in increased expression of NF2 mRNA CTD PMID:19774075 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects expression
increases expression
ISO Amiodarone affects the expression of NFE2L2 mRNA
Amiodarone results in increased expression of NFE2L2 mRNA
CTD PMID:35641671 PMID:36586010 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfic nuclear factor I/C increases expression ISO Amiodarone results in increased expression of NFIC mRNA CTD PMID:19774075 NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,253,361...8,309,936
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression ISO Amiodarone affects the expression of NFKB1 mRNA CTD PMID:35641671 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha increases expression
multiple interactions
ISO Amiodarone results in increased expression of NFKBIA mRNA
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]
CTD PMID:19774075 PMID:25073960 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Amiodarone results in increased expression of NFKBIZ mRNA CTD PMID:19774075 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression EXP Amiodarone affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
JBrowse link
G Niban1 niban apoptosis regulator 1 increases expression ISO Amiodarone results in increased expression of NIBAN1 mRNA CTD PMID:19774075 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Amiodarone affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:65,774,477...65,884,807
JBrowse link
G Nit1 nitrilase 1 affects expression EXP Amiodarone affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Amiodarone affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nme8 NME/NM23 family member 8 increases expression ISO Amiodarone results in increased expression of NME8 mRNA CTD PMID:19774075 NCBI chr17:45,237,022...45,304,948
Ensembl chr17:45,238,120...45,304,948
JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase increases expression EXP Amiodarone results in increased expression of NNT mRNA CTD PMID:17991464 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
JBrowse link
G Nol6 nucleolar protein 6 increases expression ISO Amiodarone results in increased expression of NOL6 mRNA CTD PMID:19774075 NCBI chr 5:56,259,919...56,270,540
Ensembl chr 5:56,260,830...56,270,336
JBrowse link
G Nos1ap nitric oxide synthase 1 adaptor protein increases expression ISO Amiodarone results in increased expression of NOS1AP mRNA CTD PMID:19774075 NCBI chr13:82,547,799...82,820,999
Ensembl chr13:82,530,577...82,820,949
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO Amiodarone promotes the reaction [NOS3 protein results in increased chemical synthesis of Nitric Oxide] CTD PMID:16479044 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nppa natriuretic peptide A increases expression EXP Amiodarone results in increased expression of NPPA mRNA CTD PMID:17535870 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Npsr1 neuropeptide S receptor 1 increases expression ISO Amiodarone results in increased expression of NPSR1 mRNA CTD PMID:19774075 NCBI chr 8:22,606,946...22,831,558
Ensembl chr 8:22,606,946...22,831,558
JBrowse link
G Nptxr neuronal pentraxin receptor increases expression ISO Amiodarone results in increased expression of NPTXR mRNA CTD PMID:19774075 NCBI chr 7:111,336,660...111,354,737
Ensembl chr 7:111,336,664...111,354,802
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Amiodarone results in increased expression of NQO1 mRNA CTD PMID:24535564 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO Amiodarone results in increased expression of NR1I2 mRNA CTD PMID:24489787 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression EXP Amiodarone affects the expression of NR1I3 mRNA CTD PMID:19483382 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression EXP Amiodarone affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression EXP Amiodarone results in increased expression of NR4A1 mRNA CTD PMID:22291062 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Amiodarone results in increased expression of NR4A2 mRNA CTD PMID:19774075 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nrep neuronal regeneration related protein affects expression EXP Amiodarone affects the expression of NREP mRNA CTD PMID:18355885 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591
JBrowse link
G Nrg1 neuregulin 1 increases expression ISO Amiodarone results in increased expression of NRG1 mRNA CTD PMID:36586010 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884
JBrowse link
G Nsdhl NAD(P) dependent steroid dehydrogenase-like increases expression EXP Amiodarone results in increased expression of NSDHL mRNA CTD PMID:22291062 NCBI chr  X:150,775,034...150,807,161
Ensembl chr  X:150,775,080...150,807,142
JBrowse link
G Nt5m 5',3'-nucleotidase, mitochondrial increases expression ISO Amiodarone results in increased expression of NT5M mRNA CTD PMID:19774075 NCBI chr10:44,652,845...44,680,549
Ensembl chr10:44,652,975...44,679,150
JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 increases expression ISO Amiodarone results in increased expression of NTRK3 mRNA CTD PMID:19774075 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Amiodarone results in increased expression of NUPR1 mRNA CTD PMID:15342952 PMID:17175557 PMID:17567588 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281
JBrowse link
G Oaf out at first homolog affects expression EXP Amiodarone affects the expression of OAF mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
JBrowse link
G Obp3 alpha-2u globulin PGCL4 affects expression EXP Amiodarone affects the expression of OBP3 mRNA CTD PMID:19483382 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
JBrowse link
G Ocm oncomodulin increases expression ISO Amiodarone results in increased expression of OCM mRNA CTD PMID:19774075 NCBI chr12:10,535,619...10,596,705
Ensembl chr12:10,586,897...10,596,707
JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression EXP Amiodarone affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Olr59 olfactory receptor 59 affects expression EXP Amiodarone affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
JBrowse link
G Ophn1 oligophrenin 1 increases expression ISO Amiodarone results in increased expression of OPHN1 mRNA CTD PMID:19774075 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633
JBrowse link
G Or2b2 olfactory receptor family 2 subfamily B member 2 increases expression ISO Amiodarone results in increased expression of OR2B2 mRNA CTD PMID:19774075 NCBI chr17:42,811,452...42,812,393
Ensembl chr17:42,809,046...42,817,534
Ensembl chr17:42,809,046...42,817,534
JBrowse link
G Or2d2 olfactory receptor family 2 subfamily D member 2 increases expression ISO Amiodarone results in increased expression of OR2D2 mRNA CTD PMID:19774075 NCBI chr 1:160,979,415...160,980,362
Ensembl chr 1:160,979,043...160,983,787
JBrowse link
G Or4c103b olfactory receptor family 4 subfamily C member 103B increases expression ISO Amiodarone results in increased expression of OR4C16 mRNA CTD PMID:19774075 NCBI chr 3:74,400,632...74,401,558
Ensembl chr 3:74,397,673...74,405,942
JBrowse link
G Or4f5 olfactory receptor family 4 subfamily F member 5 increases expression ISO Amiodarone results in increased expression of OR4F5 mRNA CTD PMID:19774075 NCBI chr 3:98,076,440...98,080,996 JBrowse link
G Or52n2 olfactory receptor family 52 subfamily N member 2 increases expression ISO Amiodarone results in increased expression of OR52N2 mRNA CTD PMID:19774075 NCBI chr 1:159,204,524...159,205,480
Ensembl chr 1:159,203,518...159,207,587
JBrowse link
G Or9q2 olfactory receptor family 9 subfamily Q member 2 increases expression ISO Amiodarone results in increased expression of OR9Q2 mRNA CTD PMID:19774075 NCBI chr 1:210,933,992...210,934,936
Ensembl chr 1:210,933,727...210,937,168
JBrowse link
G Osbp2 oxysterol binding protein 2 increases expression ISO Amiodarone results in increased expression of OSBP2 mRNA CTD PMID:19774075 NCBI chr14:78,585,088...78,746,785
Ensembl chr14:78,585,089...78,746,786
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit affects expression EXP Amiodarone affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
JBrowse link
G Otc ornithine transcarbamylase affects expression EXP Amiodarone affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
G Oxct1 3-oxoacid CoA transferase 1 increases expression EXP Amiodarone results in increased expression of OXCT1 mRNA CTD PMID:17991464 NCBI chr 2:53,236,370...53,384,715
Ensembl chr 2:53,236,368...53,384,714
JBrowse link
G Oxsm 3-oxoacyl-ACP synthase, mitochondrial increases expression ISO Amiodarone results in increased expression of OXSM mRNA CTD PMID:19774075 NCBI chr15:9,210,443...9,215,852
Ensembl chr15:9,210,547...9,214,558
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression EXP Amiodarone affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase affects expression EXP Amiodarone affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Amiodarone results in increased expression of PARK7 mRNA CTD PMID:24489787 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [3-methyladenine co-treated with Amiodarone] results in increased cleavage of PARP1 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of PARP1 protein CTD PMID:21292685 PMID:23912912 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pax3 paired box 3 increases expression ISO Amiodarone results in increased expression of PAX3 mRNA CTD PMID:19774075 NCBI chr 9:79,567,455...79,664,042
Ensembl chr 9:79,568,634...79,664,042
JBrowse link
G Pc pyruvate carboxylase affects expression EXP Amiodarone affects the expression of PC mRNA; Amiodarone affects the expression of PCX mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta affects expression EXP Amiodarone affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234
JBrowse link
G Pcdh1 protocadherin 1 increases expression ISO Amiodarone results in increased expression of PCDH1 mRNA CTD PMID:19774075 NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318
JBrowse link
G Pcdh7 protocadherin 7 increases expression ISO Amiodarone results in increased expression of PCDH7 mRNA CTD PMID:19774075 NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051
JBrowse link
G Pcdh8 protocadherin 8 increases expression ISO Amiodarone results in increased expression of PCDH8 mRNA CTD PMID:19774075 NCBI chr15:55,198,470...55,203,039
Ensembl chr15:55,198,459...55,205,872
JBrowse link
G Pcdhac2 protocadherin alpha subfamily C, 2 increases expression ISO Amiodarone results in increased expression of PCDHAC2 mRNA CTD PMID:19774075 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 increases expression ISO Amiodarone results in increased expression of PCDHGC3 mRNA CTD PMID:19774075 NCBI chr18:29,633,016...29,667,865
Ensembl chr18:29,493,954...29,667,868
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO Amiodarone results in increased expression of PCK2 mRNA CTD PMID:24489787 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression EXP Amiodarone results in decreased expression of PCNA mRNA CTD PMID:19224547 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression EXP Amiodarone affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 increases expression ISO Amiodarone results in increased expression of PCSK9 mRNA CTD PMID:19774075 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of PCTP mRNA
Amiodarone results in increased expression of PCTP mRNA
CTD PMID:19483382 PMID:24489787 PMID:24535564 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pcyt1a phosphate cytidylyltransferase 1A, choline increases expression EXP Amiodarone results in increased expression of PCYT1A mRNA CTD PMID:22291062 NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357
JBrowse link
G Pdcd10 programmed cell death 10 increases expression ISO Amiodarone results in increased expression of PDCD10 mRNA CTD PMID:19774075 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018
JBrowse link
G Pdcl3 phosducin-like 3 affects expression EXP Amiodarone affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
JBrowse link
G Pde6g phosphodiesterase 6G increases expression ISO Amiodarone results in increased expression of PDE6G mRNA CTD PMID:19774075 NCBI chr10:105,721,502...105,726,150
Ensembl chr10:105,721,682...105,726,719
JBrowse link
G Pde7b phosphodiesterase 7B increases expression ISO Amiodarone results in increased expression of PDE7B mRNA CTD PMID:19774075 NCBI chr 1:15,174,001...15,493,267
Ensembl chr 1:15,182,704...15,492,900
JBrowse link
G Pdf peptide deformylase (mitochondrial) increases expression ISO Amiodarone results in increased expression of PDF mRNA CTD PMID:19774075 NCBI chr19:34,949,408...34,951,621
Ensembl chr19:34,948,256...34,951,515
JBrowse link
G Pdgfrl platelet-derived growth factor receptor-like increases expression ISO Amiodarone results in increased expression of PDGFRL mRNA CTD PMID:19774075 NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Amiodarone affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 affects expression EXP Amiodarone affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO Amiodarone results in increased expression of PDK4 mRNA CTD PMID:24489787 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdlim2 PDZ and LIM domain 2 increases expression ISO Amiodarone results in increased expression of PDLIM2 mRNA CTD PMID:19774075 NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
JBrowse link
G Pdss1 decaprenyl diphosphate synthase subunit 1 increases expression ISO Amiodarone results in increased expression of PDSS1 mRNA CTD PMID:24489787 NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
JBrowse link
G Pdss2 decaprenyl diphosphate synthase subunit 2 increases expression ISO Amiodarone results in increased expression of PDSS2 mRNA CTD PMID:24489787 NCBI chr20:46,709,631...46,938,704
Ensembl chr20:46,709,649...46,938,708
JBrowse link
G Pdyn prodynorphin increases expression ISO Amiodarone results in increased expression of PDYN mRNA CTD PMID:19774075 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334
JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 increases expression ISO Amiodarone results in increased expression of PDZRN3 mRNA CTD PMID:24535564 NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959
JBrowse link
G Pecr peroxisomal trans-2-enoyl-CoA reductase affects expression EXP Amiodarone affects the expression of PECR mRNA CTD PMID:18355885 NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
JBrowse link
G Per1 period circadian regulator 1 increases expression ISO Amiodarone results in increased expression of PER1 mRNA CTD PMID:19774075 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Pex1 peroxisomal biogenesis factor 1 increases expression ISO Amiodarone results in increased expression of PEX1 mRNA CTD PMID:24489787 NCBI chr 4:30,519,950...30,558,953
Ensembl chr 4:30,519,955...30,558,921
JBrowse link
G Pex10 peroxisomal biogenesis factor 10 increases expression ISO Amiodarone results in increased expression of PEX10 mRNA CTD PMID:24489787 NCBI chr 5:165,627,799...165,632,965
Ensembl chr 5:165,627,799...165,632,965
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression ISO Amiodarone results in increased expression of PEX11A mRNA CTD PMID:24489787 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
JBrowse link
G Pex11b peroxisomal biogenesis factor 11 beta increases expression ISO Amiodarone results in increased expression of PEX11B mRNA CTD PMID:24489787 NCBI chr 2:184,172,041...184,180,972
Ensembl chr 2:184,172,004...184,181,495
JBrowse link
G Pex12 peroxisomal biogenesis factor 12 increases expression ISO Amiodarone results in increased expression of PEX12 mRNA CTD PMID:24489787 NCBI chr10:68,095,776...68,103,812
Ensembl chr10:68,095,776...68,099,428
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of PEX19 mRNA
Amiodarone results in increased expression of PEX19 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 increases expression ISO Amiodarone results in increased expression of PFKFB1 mRNA CTD PMID:24535564 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Pfkm phosphofructokinase, muscle multiple interactions ISO PFKM protein mutant form results in increased susceptibility to [Cyclosporine co-treated with Amiodarone] CTD PMID:30792690 NCBI chr 7:129,221,679...129,259,192
Ensembl chr 7:129,221,653...129,259,192
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression EXP Amiodarone affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgk2 phosphoglycerate kinase 2 increases expression ISO Amiodarone results in increased expression of PGK2 mRNA CTD PMID:19774075 NCBI chr 9:20,480,367...20,481,933
Ensembl chr 9:20,480,203...20,571,481
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression EXP Amiodarone affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682
JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 increases expression EXP Amiodarone results in increased expression of PGS1 mRNA CTD PMID:22291062 NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254
JBrowse link
G Phf20l1 PHD finger protein 20-like 1 increases expression ISO Amiodarone results in increased expression of PHF20L1 mRNA CTD PMID:19774075 NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526
JBrowse link
G Phf5a PHD finger protein 5A increases expression ISO Amiodarone results in increased expression of PHF5A mRNA CTD PMID:19774075 NCBI chr 7:113,378,469...113,385,035
Ensembl chr 7:113,378,471...113,385,460
JBrowse link
G Phka1 phosphorylase kinase regulatory subunit alpha 1 increases expression ISO Amiodarone results in increased expression of PHKA1 mRNA CTD PMID:19774075 NCBI chr  X:67,601,302...67,738,504
Ensembl chr  X:67,601,302...67,738,455
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase affects expression EXP Amiodarone affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
JBrowse link
G Piga phosphatidylinositol glycan anchor biosynthesis, class A increases expression ISO Amiodarone results in increased expression of PIGA mRNA CTD PMID:19774075 NCBI chr  X:30,043,033...30,055,861
Ensembl chr  X:30,042,343...30,055,804
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression EXP Amiodarone affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr11:33,682,943...33,689,111
Ensembl chr11:33,682,948...33,689,321
JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha increases expression ISO Amiodarone results in increased expression of PIP5K1A mRNA CTD PMID:19774075 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
JBrowse link
G Pklr pyruvate kinase L/R affects expression EXP Amiodarone affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pla2g15 phospholipase A2, group XV affects expression ISO Amiodarone affects the expression of PLA2G15 mRNA CTD PMID:29248575 NCBI chr19:34,050,685...34,068,070
Ensembl chr19:34,050,694...34,068,063
JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression EXP Amiodarone results in increased expression of PLA2G2A mRNA CTD PMID:25580480 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Pla2g4a phospholipase A2 group 4A decreases expression EXP Amiodarone results in decreased expression of PLA2G4A mRNA CTD PMID:22291062 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
JBrowse link
G Pla2g7 phospholipase A2 group VII increases expression EXP Amiodarone results in increased expression of PLA2G7 mRNA CTD PMID:25580480 NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
JBrowse link
G Plaa phospholipase A2, activating protein increases expression ISO Amiodarone results in increased expression of PLAA mRNA CTD PMID:19774075 NCBI chr 5:109,428,600...109,460,373
Ensembl chr 5:109,428,265...109,460,282
JBrowse link
G Plaat3 phospholipase A and acyltransferase 3 increases expression ISO Amiodarone results in increased expression of PLAAT3 mRNA CTD PMID:24535564 NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
JBrowse link
G Plac8l1 PLAC8-like 1 increases expression ISO Amiodarone results in increased expression of PLAC8L1 mRNA CTD PMID:19774075 NCBI chr18:34,167,667...34,192,137
Ensembl chr18:34,168,864...34,190,800
JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression EXP Amiodarone affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
JBrowse link
G Plcg1 phospholipase C, gamma 1 decreases expression EXP Amiodarone results in decreased expression of PLCG1 protein CTD PMID:21224497 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Pld1 phospholipase D1 decreases expression EXP Amiodarone results in decreased expression of PLD1 mRNA CTD PMID:22291062 NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
JBrowse link
G Plekhg4 pleckstrin homology and RhoGEF domain containing G4 increases expression ISO Amiodarone results in increased expression of PLEKHG4 mRNA CTD PMID:19774075 NCBI chr19:33,251,788...33,266,490
Ensembl chr19:33,249,706...33,266,357
JBrowse link
G Plg plasminogen affects expression EXP Amiodarone affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Pls1 plastin 1 increases expression ISO Amiodarone results in increased expression of PLS1 mRNA CTD PMID:19774075 NCBI chr 8:96,316,703...96,426,592
Ensembl chr 8:96,317,849...96,385,195
JBrowse link
G Pls3 plastin 3 affects expression EXP Amiodarone affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pltp phospholipid transfer protein increases expression ISO Amiodarone results in increased expression of PLTP mRNA CTD PMID:24535564 NCBI chr 3:153,574,825...153,592,647
Ensembl chr 3:153,574,825...153,592,647
JBrowse link
G Pmm1 phosphomannomutase 1 increases expression ISO Amiodarone results in increased expression of PMM1 mRNA CTD PMID:24489787 NCBI chr 7:113,466,632...113,477,004
Ensembl chr 7:113,466,632...113,477,022
JBrowse link
G Pmvk phosphomevalonate kinase increases expression ISO
EXP
Amiodarone results in increased expression of PMVK mRNA CTD PMID:22291062 PMID:24535564 NCBI chr 2:174,876,586...174,886,365
Ensembl chr 2:174,876,657...174,886,364
JBrowse link
G Podn podocan increases expression ISO Amiodarone results in increased expression of PODN mRNA CTD PMID:19774075 NCBI chr 5:122,774,536...122,796,755
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Poll DNA polymerase lambda increases expression ISO Amiodarone results in increased expression of POLL mRNA CTD PMID:19774075 NCBI chr 1:244,400,202...244,408,762
Ensembl chr 1:244,400,204...244,408,662
JBrowse link
G Pon2 paraoxonase 2 affects expression EXP Amiodarone affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Por cytochrome p450 oxidoreductase affects expression EXP Amiodarone affects the expression of POR mRNA CTD PMID:18355885 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Poteh POTE ankyrin domain family member H increases expression ISO Amiodarone results in increased expression of POTEH mRNA CTD PMID:19774075 NCBI chr15:17,131,582...17,219,924 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
decreases expression
increases response to substance
EXP
ISO
Amiodarone results in increased expression of PPARA mRNA
Amiodarone results in decreased expression of PPARA mRNA
PPARA protein results in increased susceptibility to Amiodarone
CTD PMID:15265979 PMID:19224547 PMID:24489787 PMID:30685923 PMID:32084307 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
decreases expression
increases expression
ISO [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of SCD mRNA]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]; Amiodarone binds to and results in increased activity of PPARG protein
Amiodarone results in decreased expression of PPARG mRNA
Amiodarone results in increased expression of PPARG mRNA
CTD PMID:21123845 PMID:24489787 PMID:35641671 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha increases expression ISO Amiodarone results in increased expression of PPARGC1A mRNA CTD PMID:27089845 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases expression ISO Amiodarone results in increased expression of PPARGC1B mRNA CTD PMID:24489787 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression EXP Amiodarone affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036
JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B increases expression ISO Amiodarone results in increased expression of PPM1B mRNA CTD PMID:19774075 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Amiodarone results in increased expression of PPP1R15A mRNA CTD PMID:19774075 PMID:36586010 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma increases expression ISO Amiodarone results in increased expression of PPP2R5C mRNA CTD PMID:19774075 NCBI chr 6:129,461,689...129,598,344
Ensembl chr 6:129,461,648...129,598,346
JBrowse link
G Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha increases expression ISO Amiodarone results in increased expression of PPP3R1 mRNA CTD PMID:19774075 NCBI chr14:91,556,743...91,606,391
Ensembl chr14:91,604,121...91,606,907
JBrowse link
G Prdm2 PR/SET domain 2 increases expression ISO Amiodarone results in increased expression of PRDM2 mRNA CTD PMID:19774075 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
JBrowse link
G Prdm8 PR/SET domain 8 increases expression ISO Amiodarone results in increased expression of PRDM8 mRNA CTD PMID:19774075 NCBI chr14:11,403,202...11,424,059
Ensembl chr14:11,404,407...11,410,993
JBrowse link
G Prdx1 peroxiredoxin 1 decreases expression ISO Amiodarone results in decreased expression of PRDX1 mRNA CTD PMID:36586010 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Prdx2 peroxiredoxin 2 affects expression EXP Amiodarone affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx3 peroxiredoxin 3 increases expression ISO Amiodarone results in increased expression of PRDX3 mRNA CTD PMID:24489787 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
JBrowse link
G Prdx6 peroxiredoxin 6 affects expression EXP Amiodarone affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prim2 DNA primase subunit 2 increases expression ISO Amiodarone results in increased expression of PRIM2 mRNA CTD PMID:19774075 NCBI chr 9:35,692,376...35,904,521
Ensembl chr 9:35,692,376...35,903,030
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Amiodarone results in increased phosphorylation of PRKAA1 protein CTD PMID:23912912 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 increases phosphorylation ISO Amiodarone results in increased phosphorylation of PRKAA2 protein CTD PMID:23912912 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
JBrowse link
G Prl prolactin decreases expression EXP Amiodarone results in decreased expression of PRL mRNA CTD PMID:3427795 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
JBrowse link
G Prmt1 protein arginine methyltransferase 1 increases expression ISO Amiodarone results in increased expression of PRMT1 mRNA CTD PMID:19774075 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa affects expression EXP Amiodarone affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Proser2 proline and serine rich 2 increases expression ISO Amiodarone results in increased expression of PROSER2 mRNA CTD PMID:19774075 NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825
JBrowse link
G Prox1 prospero homeobox 1 increases expression ISO Amiodarone results in increased expression of PROX1 mRNA CTD PMID:19774075 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression EXP Amiodarone affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
JBrowse link
G Prr19 proline rich 19 increases expression ISO Amiodarone results in increased expression of PRR19 mRNA CTD PMID:19774075 NCBI chr 1:80,884,529...80,890,712
Ensembl chr 1:80,887,151...80,890,168
JBrowse link
G Psca prostate stem cell antigen decreases expression EXP Amiodarone results in decreased expression of PSCA mRNA CTD PMID:17991464 NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746
JBrowse link
G Psen1 presenilin 1 increases expression ISO Amiodarone results in increased expression of PSEN1 mRNA CTD PMID:19774075 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Psip1 PC4 and SRSF1 interacting protein 1 increases expression ISO Amiodarone results in increased expression of PSIP1 mRNA CTD PMID:19774075 NCBI chr 5:97,847,010...97,879,280
Ensembl chr 5:97,847,015...97,879,257
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 affects expression EXP Amiodarone affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects expression EXP Amiodarone affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 affects expression EXP Amiodarone affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 affects expression EXP Amiodarone affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 affects expression EXP Amiodarone affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 affects expression EXP Amiodarone affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 affects expression EXP Amiodarone affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Psmd11 proteasome 26S subunit, non-ATPase 11 increases expression ISO Amiodarone results in increased expression of PSMD11 mRNA CTD PMID:19774075 NCBI chr10:65,433,853...65,479,774
Ensembl chr10:65,433,853...65,479,766
JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 affects expression EXP Amiodarone affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Amiodarone results in increased expression of PTGR1 mRNA CTD PMID:19774075 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Amiodarone results in increased expression of PTGS2 mRNA CTD PMID:19774075 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptms parathymosin affects expression EXP Amiodarone affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 increases expression ISO Amiodarone results in increased expression of PTPN3 mRNA CTD PMID:19774075 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of PTPRF mRNA
Amiodarone affects the expression of PTPRF mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N increases expression ISO Amiodarone results in increased expression of PTPRN mRNA CTD PMID:19774075 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Pttg1ip PTTG1 interacting protein affects expression EXP Amiodarone affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
JBrowse link
G Pxmp4 peroxisomal membrane protein 4 increases expression ISO Amiodarone results in increased expression of PXMP4 mRNA CTD PMID:24489787 NCBI chr 3:143,093,371...143,110,620
Ensembl chr 3:143,093,018...143,110,651
JBrowse link
G Pygl glycogen phosphorylase L affects expression EXP Amiodarone affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Pygo1 pygopus family PHD finger 1 increases expression ISO Amiodarone results in increased expression of PYGO1 mRNA CTD PMID:19774075 NCBI chr 8:73,666,210...73,684,873
Ensembl chr 8:73,665,593...73,684,869
JBrowse link
G Qpct glutaminyl-peptide cyclotransferase increases expression ISO Amiodarone results in increased expression of QPCT mRNA CTD PMID:24535564 NCBI chr 6:15,964,656...15,996,730
Ensembl chr 6:15,964,657...15,996,711
JBrowse link
G Rab5if RAB5 interacting factor affects expression EXP Amiodarone affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012
JBrowse link
G Rab9b RAB9B, member RAS oncogene family increases expression ISO Amiodarone results in increased expression of RAB9B mRNA CTD PMID:19774075 NCBI chr  X:100,220,897...100,231,591
Ensembl chr  X:100,220,894...100,231,701
JBrowse link
G Rac3 Rac family small GTPase 3 increases expression ISO Amiodarone results in increased expression of RAC3 mRNA CTD PMID:19774075 NCBI chr10:106,002,808...106,005,243
Ensembl chr10:105,993,087...106,005,260
JBrowse link
G Rad51b RAD51 paralog B increases expression ISO Amiodarone results in increased expression of RAD51B mRNA CTD PMID:24535564 NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979
JBrowse link
G Rbbp8 RB binding protein 8, endonuclease increases expression ISO Amiodarone results in increased expression of RBBP8 mRNA CTD PMID:19774075 NCBI chr18:2,922,985...2,988,851
Ensembl chr18:2,921,286...2,988,846
JBrowse link
G Rbks ribokinase increases expression ISO Amiodarone results in increased expression of RBKS mRNA CTD PMID:19774075 NCBI chr 6:24,747,651...24,824,290
Ensembl chr 6:24,747,293...24,824,290
JBrowse link
G Rbl2 RB transcriptional corepressor like 2 affects expression EXP Amiodarone affects the expression of RBL2 mRNA CTD PMID:18355885 NCBI chr19:15,876,852...15,923,632
Ensembl chr19:15,876,853...15,923,572
JBrowse link
G Rbm33 RNA binding motif protein 33 increases expression ISO Amiodarone results in increased expression of RBM33 mRNA CTD PMID:19774075 NCBI chr 4:6,980,807...7,088,334
Ensembl chr 4:6,983,970...7,089,918
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Amiodarone results in increased expression of RBPMS mRNA CTD PMID:19774075 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
JBrowse link
G Rcc1l RCC1 like increases expression ISO Amiodarone results in increased expression of RCC1L mRNA CTD PMID:19774075 NCBI chr12:22,543,125...22,574,042
Ensembl chr12:22,543,734...22,574,036
JBrowse link
G Rcn3 reticulocalbin 3 increases expression ISO Amiodarone results in increased expression of RCN3 mRNA CTD PMID:19774075 NCBI chr 1:95,564,503...95,573,762
Ensembl chr 1:95,564,380...95,573,725
JBrowse link
G Rdh8 retinol dehydrogenase 8 increases expression ISO Amiodarone results in increased expression of RDH8 mRNA CTD PMID:19774075 NCBI chr 8:19,353,191...19,360,462
Ensembl chr 8:19,353,191...19,360,462
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Amiodarone results in increased expression of RELB mRNA CTD PMID:19774075 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Repin1 replication initiator 1 increases expression ISO Amiodarone results in increased expression of REPIN1 mRNA CTD PMID:19774075 NCBI chr 4:77,548,724...77,554,242
Ensembl chr 4:77,548,849...77,554,257
JBrowse link
G Retsat retinol saturase increases expression ISO Amiodarone results in increased expression of RETSAT mRNA CTD PMID:24535564 NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
JBrowse link
G Rgn regucalcin decreases expression EXP Amiodarone results in decreased expression of RGN mRNA CTD PMID:12883083 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450
JBrowse link
G Rgs6 regulator of G-protein signaling 6 increases expression ISO Amiodarone results in increased expression of RGS6 mRNA CTD PMID:19774075 NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753
JBrowse link
G Rhebl1 RHEB like 1 increases expression ISO Amiodarone results in increased expression of RHEBL1 mRNA CTD PMID:19774075 NCBI chr 7:130,026,255...130,031,127
Ensembl chr 7:130,026,341...130,030,248
JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression EXP Amiodarone affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
JBrowse link
G Rin3 Ras and Rab interactor 3 increases expression ISO Amiodarone results in increased expression of RIN3 mRNA CTD PMID:19774075 NCBI chr 6:121,431,776...121,540,956
Ensembl chr 6:121,431,339...121,540,957
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression EXP Amiodarone affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr15:24,312,765...24,330,112
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Rnf103 ring finger protein 103 affects expression EXP Amiodarone affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919
JBrowse link
G Rnf146 ring finger protein 146 increases expression ISO Amiodarone results in increased expression of RNF146 mRNA CTD PMID:19774075 NCBI chr 1:28,458,864...28,475,758
Ensembl chr 1:28,458,887...28,475,923
JBrowse link
G Rnf19a ring finger protein 19A, RBR E3 ubiquitin protein ligase increases expression ISO Amiodarone results in increased expression of RNF19A mRNA CTD PMID:19774075 NCBI chr 7:67,425,833...67,465,214
Ensembl chr 7:67,425,837...67,465,222
JBrowse link
G Rnf212 ring finger protein 212 increases expression ISO Amiodarone results in increased expression of RNF212 mRNA CTD PMID:19774075 NCBI chr14:949,397...988,377
Ensembl chr14:949,448...987,831
JBrowse link
G Rnf6 ring finger protein 6 increases expression ISO Amiodarone results in increased expression of RNF6 mRNA CTD PMID:19774075 NCBI chr12:8,816,797...8,826,870
Ensembl chr12:8,816,833...8,826,847
JBrowse link
G Rnf8 ring finger protein 8 increases expression ISO Amiodarone results in increased expression of RNF8 mRNA CTD PMID:19774075 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491
JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression EXP Amiodarone affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858
JBrowse link
G Rpl11 ribosomal protein L11 affects expression EXP Amiodarone affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl13 ribosomal protein L13 affects expression EXP Amiodarone affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl15 ribosomal protein L15 affects expression EXP Amiodarone affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
JBrowse link
G Rpl17 ribosomal protein L17 affects expression EXP Amiodarone affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:68,581,141...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rpl23 ribosomal protein L23 affects expression EXP Amiodarone affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl3 ribosomal protein L3 affects expression EXP Amiodarone affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
JBrowse link
G Rpl32 ribosomal protein L32 affects expression EXP Amiodarone affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
JBrowse link
G Rpl36a ribosomal protein L36A increases expression ISO Amiodarone results in increased expression of RPL36A mRNA CTD PMID:19774075 NCBI chr  X:97,766,179...97,768,892
Ensembl chr  X:97,766,179...97,768,892
JBrowse link
G Rpl4 ribosomal protein L4 affects expression EXP Amiodarone affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
JBrowse link
G Rpn2 ribophorin II affects expression EXP Amiodarone affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
JBrowse link
G Rps14 ribosomal protein S14 affects expression EXP Amiodarone affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
JBrowse link
G Rps18 ribosomal protein S18 affects expression EXP Amiodarone affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146
JBrowse link
G Rps19 ribosomal protein S19 affects expression EXP Amiodarone affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
JBrowse link
G Rps20 ribosomal protein S20 affects expression EXP Amiodarone affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 5:16,819,095...16,820,476
Ensembl chr 5:16,819,304...16,820,475
Ensembl chr 9:16,819,304...16,820,475
Ensembl chr 3:16,819,304...16,820,475
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Amiodarone affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps6 ribosomal protein S6 affects expression EXP Amiodarone affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO Amiodarone results in decreased phosphorylation of RPS6KB1 protein CTD PMID:23912912 PMID:25881747 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rps8 ribosomal protein S8 affects expression EXP Amiodarone affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rras2 RAS related 2 affects expression EXP Amiodarone affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
JBrowse link
G RT1-Hb-ps1 RT1 class II, locus Hb, pseudogene 1 increases expression ISO Amiodarone results in increased expression of HLA-DPB1 mRNA CTD PMID:19774075 NCBI chr20:4,775,598...4,779,590
Ensembl chr20:4,774,650...4,780,618
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression EXP Amiodarone affects the expression of RT1-S3 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G Rtn4 reticulon 4 increases expression ISO Amiodarone results in increased expression of RTN4 mRNA CTD PMID:24535564 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686
JBrowse link
G Rundc3a RUN domain containing 3A increases expression ISO Amiodarone results in increased expression of RUNDC3A mRNA CTD PMID:19774075 NCBI chr10:87,352,624...87,361,767
Ensembl chr10:87,352,646...87,361,765
JBrowse link
G Rxrg retinoid X receptor gamma increases expression ISO Amiodarone results in increased expression of RXRG mRNA CTD PMID:24489787 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G S100a10 S100 calcium binding protein A10 increases expression ISO Amiodarone results in increased expression of S100A10 mRNA CTD PMID:24535564 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression EXP Amiodarone affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Sardh sarcosine dehydrogenase increases expression ISO Amiodarone results in increased expression of SARDH mRNA CTD PMID:19774075 NCBI chr 3:10,510,553...10,575,342
Ensembl chr 3:10,510,553...10,573,874
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression EXP Amiodarone affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420
JBrowse link
G Sc5d sterol-C5-desaturase increases expression EXP Amiodarone results in increased expression of SC5D mRNA CTD PMID:22291062 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273
JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) decreases expression EXP Amiodarone results in decreased expression of SCCPDH mRNA CTD PMID:17991464 NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
decreases expression
increases expression
ISO
EXP
[2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of SCD mRNA]; SCD protein affects the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]
Amiodarone results in decreased expression of SCD1 mRNA; Amiodarone results in decreased expression of SCD1 protein
Amiodarone results in increased expression of SCD1 mRNA
CTD PMID:17202758 PMID:19224547 PMID:21123845 PMID:29248575 PMID:32535746 More... NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 increases expression EXP Amiodarone results in increased expression of SCGB1A1 protein CTD PMID:32909452 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Scimp SLP adaptor and CSK interacting membrane protein increases expression ISO Amiodarone results in increased expression of SCIMP mRNA CTD PMID:19774075 NCBI chr10:55,507,646...55,527,764
Ensembl chr10:55,507,519...55,528,171
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 decreases expression ISO Amiodarone results in decreased expression of SCN1B mRNA CTD PMID:15520326 NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
JBrowse link
G Scn4a sodium voltage-gated channel alpha subunit 4 decreases expression ISO Amiodarone results in decreased expression of SCN4A mRNA CTD PMID:15520326 NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545
JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 decreases expression
affects response to substance
ISO Amiodarone results in decreased expression of SCN5A mRNA
SCN5A polymorphism affects the susceptibility to Amiodarone
CTD PMID:15520326 PMID:33824187 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769
JBrowse link
G Sdc2 syndecan 2 affects expression EXP Amiodarone affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C affects expression EXP Amiodarone affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D affects expression EXP Amiodarone affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 8:50,944,702...50,954,298
Ensembl chr 8:50,944,704...50,954,238
JBrowse link
G Sdr9c7 short chain dehydrogenase/reductase family 9C, member 7 decreases expression ISO Amiodarone results in decreased expression of SDR9C7 mRNA CTD PMID:24535564 NCBI chr 7:63,703,788...63,720,325
Ensembl chr 7:63,707,071...63,721,480
JBrowse link
G Sema3d semaphorin 3D increases expression ISO Amiodarone results in increased expression of SEMA3D mRNA CTD PMID:19774075 NCBI chr 4:22,316,769...22,505,930
Ensembl chr 4:22,316,779...22,505,930
JBrowse link
G Sema4d semaphorin 4D increases expression ISO Amiodarone results in increased expression of SEMA4D mRNA CTD PMID:19774075 NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138
JBrowse link
G Sema6b semaphorin 6B increases expression ISO Amiodarone results in increased expression of SEMA6B mRNA CTD PMID:19774075 NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521
JBrowse link
G Semg1 semenogelin 1 increases expression ISO Amiodarone results in increased expression of SEMG1 mRNA CTD PMID:19774075 NCBI chr 3:152,910,033...152,912,882
Ensembl chr 3:152,910,034...152,912,882
JBrowse link
G Serinc3 serine incorporator 3 affects expression EXP Amiodarone affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
JBrowse link
G Serpina1 serpin family A member 1 affects expression EXP Amiodarone affects the expression of SERPINA1 mRNA CTD PMID:19483382 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpina10 serpin family A member 10 increases expression
affects expression
ISO
EXP
Amiodarone results in increased expression of SERPINA10 mRNA
Amiodarone affects the expression of SERPINA10 mRNA
CTD PMID:19483382 PMID:19774075 NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544
JBrowse link
G Serpina11 serpin family A member 11 decreases expression ISO Amiodarone results in decreased expression of SERPINA11 mRNA CTD PMID:24535564 NCBI chr 6:122,903,246...122,912,695
Ensembl chr 6:122,903,250...122,912,670
JBrowse link
G Serpina12 serpin family A member 12 decreases expression ISO Amiodarone results in decreased expression of SERPINA12 mRNA CTD PMID:24535564 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271
JBrowse link
G Serpina4 serpin family A member 4 affects expression EXP Amiodarone affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082
JBrowse link
G Serpina9 serpin family A member 9 decreases expression ISO Amiodarone results in decreased expression of SERPINA9 mRNA CTD PMID:24535564 NCBI chr 6:122,918,819...122,936,000
Ensembl chr 6:122,918,880...122,936,000
JBrowse link
G Serpinb1a serpin family B member 1A increases expression ISO Amiodarone results in increased expression of SERPINB1A mRNA CTD PMID:24535564 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Serpinf2 serpin family F member 2 affects expression EXP Amiodarone affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Sertad3 SERTA domain containing 3 increases expression ISO Amiodarone results in increased expression of SERTAD3 mRNA CTD PMID:19774075 NCBI chr 1:82,763,535...82,767,271
Ensembl chr 1:82,763,149...82,769,001
JBrowse link
G Sesn2 sestrin 2 increases expression ISO Amiodarone results in increased expression of SESN2 mRNA CTD PMID:19774075 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sftpb surfactant protein B increases metabolic processing ISO Amiodarone results in increased metabolism of SFTPB protein CTD PMID:25163675 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sftpc surfactant protein C increases metabolic processing ISO Amiodarone results in increased metabolism of SFTPC protein CTD PMID:25163675 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
JBrowse link
G Sfxn1 sideroflexin 1 affects expression EXP Amiodarone affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
JBrowse link
G Sh2d1a SH2 domain containing 1A increases expression ISO Amiodarone results in increased expression of SH2D1A mRNA CTD PMID:19774075 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sh3gl3 SH3 domain containing GRB2 like 3, endophilin A3 affects expression EXP Amiodarone affects the expression of SH3GL3 mRNA CTD PMID:18355885 NCBI chr 1:136,124,500...136,255,669
Ensembl chr 1:136,124,499...136,255,584
JBrowse link
G Shld2 shieldin complex subunit 2 decreases expression ISO Amiodarone results in decreased expression of SHLD2 mRNA CTD PMID:24535564 NCBI chr16:9,544,940...9,640,323
Ensembl chr16:9,548,660...9,639,965
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 affects expression EXP Amiodarone affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Sipa1l3 signal-induced proliferation-associated 1 like 3 increases expression ISO Amiodarone results in increased expression of SIPA1L3 mRNA CTD PMID:19774075 NCBI chr 1:84,618,714...84,825,956
Ensembl chr 1:84,618,719...84,703,802
JBrowse link
G Sirt4 sirtuin 4 increases expression ISO Amiodarone results in increased expression of SIRT4 mRNA CTD PMID:19774075 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
G Siva1 SIVA1, apoptosis-inducing factor increases expression ISO Amiodarone results in increased expression of SIVA1 mRNA CTD PMID:24535564 NCBI chr 6:131,705,323...131,709,697
Ensembl chr 6:131,705,323...131,709,690
JBrowse link
G Six1 SIX homeobox 1 increases expression ISO Amiodarone results in increased expression of SIX1 mRNA CTD PMID:19774075 NCBI chr 6:91,746,739...91,751,975
Ensembl chr 6:91,746,739...91,751,975
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP Amiodarone results in decreased expression of SLC10A1 mRNA CTD PMID:27765674 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc13a4 solute carrier family 13 member 4 increases expression ISO Amiodarone results in increased expression of SLC13A4 mRNA CTD PMID:19774075 NCBI chr 4:63,943,369...63,988,852
Ensembl chr 4:63,943,395...63,988,857
JBrowse link
G Slc14a2 solute carrier family 14 member 2 increases expression ISO Amiodarone results in increased expression of SLC14A2 mRNA CTD PMID:19774075 NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968
JBrowse link
G Slc16a11 solute carrier family 16, member 11 increases expression ISO Amiodarone results in increased expression of SLC16A11 mRNA CTD PMID:24535564 NCBI chr10:54,929,129...54,933,021
Ensembl chr10:54,927,725...54,942,915
JBrowse link
G Slc16a7 solute carrier family 16 member 7 increases expression ISO Amiodarone results in increased expression of SLC16A7 mRNA CTD PMID:24535564 NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
JBrowse link
G Slc17a2 solute carrier family 17, member 2 decreases expression ISO Amiodarone results in decreased expression of SLC17A2 mRNA CTD PMID:24535564 NCBI chr17:41,318,312...41,339,012
Ensembl chr17:41,319,701...41,336,325
JBrowse link
G Slc1a3 solute carrier family 1 member 3 increases expression ISO Amiodarone results in increased expression of SLC1A3 mRNA CTD PMID:36586010 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
JBrowse link
G Slc22a1 solute carrier family 22 member 1 affects expression
multiple interactions
EXP
ISO
Amiodarone affects the expression of SLC22A1 mRNA
Amiodarone inhibits the reaction [SLC22A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium]
CTD PMID:19483382 PMID:21641380 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions
decreases expression
ISO
EXP
Amiodarone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine]
Amiodarone results in decreased expression of SLC22A5 mRNA
CTD PMID:21641380 PMID:32084307 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc23a1 solute carrier family 23 member 1 affects expression EXP Amiodarone affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
JBrowse link
G Slc25a13 solute carrier family 25 member 13 affects expression EXP Amiodarone affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902
JBrowse link
G Slc25a18 solute carrier family 25 member 18 increases expression ISO Amiodarone results in increased expression of SLC25A18 mRNA CTD PMID:19774075 NCBI chr 4:154,000,808...154,021,373
Ensembl chr 4:154,000,990...154,021,372
JBrowse link
G Slc25a20 solute carrier family 25 member 20 decreases expression EXP Amiodarone results in decreased expression of SLC25A20 mRNA CTD PMID:32084307 NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
JBrowse link
G Slc25a25 solute carrier family 25 member 25 increases expression ISO Amiodarone results in increased expression of SLC25A25 mRNA CTD PMID:19774075 NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
JBrowse link
G Slc25a26 solute carrier family 25 member 26 increases expression ISO Amiodarone results in increased expression of SLC25A26 mRNA CTD PMID:19774075 NCBI chr 4:127,036,704...127,131,026
Ensembl chr 4:127,036,742...127,131,020
JBrowse link
G Slc25a3 solute carrier family 25 member 3 affects expression EXP Amiodarone affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Slc25a30 solute carrier family 25, member 30 increases expression ISO Amiodarone results in increased expression of SLC25A30 mRNA CTD PMID:19774075 NCBI chr15:51,076,998...51,099,613
Ensembl chr15:51,077,002...51,099,613
JBrowse link
G Slc26a4 solute carrier family 26 member 4 decreases expression ISO Amiodarone results in decreased expression of SLC26A4 mRNA CTD PMID:18020914 NCBI chr 6:48,107,575...48,153,762
Ensembl chr 6:48,107,588...48,145,703
JBrowse link
G Slc27a2 solute carrier family 27 member 2 affects expression EXP Amiodarone affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Amiodarone results in decreased expression of SLC2A1 mRNA CTD PMID:36586010 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Amiodarone results in decreased expression of SLC2A3 mRNA CTD PMID:15342952 PMID:17567588 PMID:29248575 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression ISO Amiodarone results in increased expression of SLC30A1 mRNA CTD PMID:19774075 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc35a2 solute carrier family 35 member A2 increases expression ISO Amiodarone results in increased expression of SLC35A2 mRNA CTD PMID:19774075 NCBI chr  X:14,608,145...14,616,937
Ensembl chr  X:14,608,055...14,616,678
JBrowse link
G Slc38a11 solute carrier family 38, member 11 increases expression ISO Amiodarone results in increased expression of SLC38A11 mRNA CTD PMID:19774075 NCBI chr 3:49,987,119...50,033,615
Ensembl chr 3:49,987,124...50,033,615
JBrowse link
G Slc39a8 solute carrier family 39 member 8 affects expression EXP Amiodarone affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Amiodarone results in increased expression of SLC3A2 mRNA CTD PMID:19774075 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Slc41a2 solute carrier family 41 member 2 decreases expression ISO Amiodarone results in decreased expression of SLC41A2 mRNA CTD PMID:24535564 NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166
JBrowse link
G Slc44a4 solute carrier family 44, member 4 decreases expression EXP Amiodarone results in decreased expression of SLC44A4 mRNA CTD PMID:17991464 NCBI chr20:3,903,099...3,919,215
Ensembl chr20:3,903,099...3,919,215
JBrowse link
G Slc46a1 solute carrier family 46 member 1 affects expression EXP Amiodarone affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression ISO Amiodarone results in increased expression of SLC4A4 mRNA CTD PMID:24535564 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
JBrowse link
G Slc5a3 solute carrier family 5 member 3 increases expression ISO Amiodarone results in increased expression of SLC5A3 mRNA CTD PMID:19774075 NCBI chr11:31,313,847...31,316,293
Ensembl chr11:31,295,476...31,318,883
JBrowse link
G Slc5a5 solute carrier family 5 member 5 decreases expression ISO Amiodarone results in decreased expression of SLC5A5 mRNA CTD PMID:18020914 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697
JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression EXP Amiodarone affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:73,702,472...73,739,678
Ensembl chr18:73,702,564...73,739,676
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression EXP Amiodarone affects the expression of SLC6A6 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Amiodarone results in increased expression of SLC7A11 mRNA CTD PMID:36586010 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
JBrowse link
G Slc8a1 solute carrier family 8 member A1 increases expression EXP Amiodarone results in increased expression of SLC8A1 protein CTD PMID:7573397 PMID:12479229 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628
JBrowse link
G Slc8a3 solute carrier family 8 member A3 decreases activity EXP Amiodarone results in decreased activity of SLC8A3 protein CTD PMID:15288574 NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects expression EXP Amiodarone affects the expression of SLCO1A4 mRNA CTD PMID:18355885 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases uptake ISO SLCO2B1 protein results in increased uptake of Amiodarone CTD PMID:19285480 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 increases expression ISO Amiodarone results in increased expression of SLCO4C1 mRNA CTD PMID:19774075 NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715
JBrowse link
G Slco5a1 solute carrier organic anion transporter family, member 5A1 increases expression ISO Amiodarone results in increased expression of SLCO5A1 mRNA CTD PMID:19774075 NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913
JBrowse link
G Slfn5 schlafen family member 5 increases expression ISO Amiodarone results in increased expression of SLFN5 mRNA CTD PMID:19774075 NCBI chr10:67,881,068...67,895,013
Ensembl chr10:67,880,009...67,893,109
JBrowse link
G Slitrk3 SLIT and NTRK-like family, member 3 increases expression ISO Amiodarone results in increased expression of SLITRK3 mRNA CTD PMID:19774075 NCBI chr 2:157,680,067...157,697,404
Ensembl chr 2:157,687,535...157,696,709
JBrowse link
G Slx4ip SLX4 interacting protein increases expression ISO Amiodarone results in increased expression of SLX4IP mRNA CTD PMID:19774075 NCBI chr 3:124,220,215...124,396,797
Ensembl chr 3:124,221,198...124,396,797
JBrowse link
G Smg6 SMG6 nonsense mediated mRNA decay factor increases expression ISO Amiodarone results in increased expression of SMG6 mRNA CTD PMID:19774075 NCBI chr10:59,786,258...60,014,395
Ensembl chr10:59,786,258...60,014,395
JBrowse link
G Smim11 small integral membrane protein 11 increases expression ISO Amiodarone results in increased expression of SMIM11 mRNA CTD PMID:19774075 NCBI chr11:31,533,257...31,543,002
Ensembl chr11:31,532,764...31,543,002
JBrowse link
G Smox spermine oxidase increases expression ISO Amiodarone results in increased expression of SMOX mRNA CTD PMID:19774075 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression
multiple interactions
ISO Amiodarone results in decreased expression of SNAI1 protein
Amiodarone affects the reaction [VCAN protein alternative form affects the expression of SNAI1 protein]; MAP2K1 protein inhibits the reaction [Amiodarone results in decreased expression of SNAI1 protein]
CTD PMID:26515726 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snrnp35 small nuclear ribonucleoprotein U11/U12 subunit 35 increases expression ISO Amiodarone results in increased expression of SNRNP35 mRNA CTD PMID:19774075 NCBI chr12:32,112,032...32,119,829
Ensembl chr12:32,110,993...32,122,660
JBrowse link
G Snx18 sorting nexin 18 increases expression ISO Amiodarone results in increased expression of SNX18 mRNA CTD PMID:19774075 NCBI chr 2:45,232,325...45,258,345
Ensembl chr 2:45,232,325...45,258,345
JBrowse link
G Socs6 suppressor of cytokine signaling 6 increases expression ISO Amiodarone results in increased expression of SOCS6 mRNA CTD PMID:19774075 NCBI chr18:82,111,866...82,139,193
Ensembl chr18:82,111,827...82,139,219
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
multiple interactions
ISO Amiodarone results in decreased expression of SOD1 mRNA
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]]
CTD PMID:34434487 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases expression
ISO Amiodarone results in increased expression of SOD2 mRNA; Amiodarone results in increased expression of SOD2 protein
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]]
CTD PMID:23135547 PMID:28526448 PMID:34434487 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spag1 sperm associated antigen 1 increases expression ISO Amiodarone results in increased expression of SPAG1 mRNA CTD PMID:19774075 NCBI chr 7:67,361,474...67,421,369
Ensembl chr 7:67,361,477...67,421,368
JBrowse link
G Spata17 spermatogenesis associated 17 increases expression ISO Amiodarone results in increased expression of SPATA17 mRNA CTD PMID:19774075 NCBI chr13:98,605,986...98,784,855
Ensembl chr13:98,605,986...98,784,929
JBrowse link
G Spata2L spermatogenesis associated 2-like increases expression ISO Amiodarone results in increased expression of SPATA2L mRNA CTD PMID:19774075 NCBI chr19:51,269,078...51,273,605
Ensembl chr19:51,269,078...51,273,510
JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex increases expression ISO Amiodarone results in increased expression of SPC24 mRNA CTD PMID:24535564 NCBI chr 8:20,300,315...20,305,354
Ensembl chr 8:20,300,319...20,305,310
JBrowse link
G Spef2 sperm flagellar 2 increases expression ISO Amiodarone results in increased expression of SPEF2 mRNA CTD PMID:19774075 NCBI chr 2:58,512,489...58,694,718
Ensembl chr 2:58,512,489...58,694,664
JBrowse link
G Spmip4 sperm microtubule inner protein 4 increases expression ISO Amiodarone results in increased expression of SPMIP4 mRNA CTD PMID:19774075 NCBI chr 4:79,663,375...79,688,291
Ensembl chr 4:79,663,376...79,689,072
JBrowse link
G Spopl speckle type BTB/POZ protein like increases expression ISO Amiodarone results in increased expression of SPOPL mRNA CTD PMID:19774075 NCBI chr 3:6,074,681...6,148,508
Ensembl chr 3:6,078,310...6,108,794
JBrowse link
G Sppl2a signal peptide peptidase-like 2A affects expression EXP Amiodarone affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:114,151,069...114,193,264
JBrowse link
G Spr sepiapterin reductase increases expression ISO Amiodarone results in increased expression of SPR mRNA CTD PMID:19774075 NCBI chr 4:117,671,948...117,676,292
Ensembl chr 4:117,671,949...117,675,678
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 increases expression ISO Amiodarone results in increased expression of SPTBN1 mRNA CTD PMID:19774075 NCBI chr14:103,841,713...104,016,900
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Sqle squalene epoxidase increases expression ISO Amiodarone results in increased expression of SQLE mRNA CTD PMID:24489787 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Sqstm1 sequestosome 1 increases expression
affects expression
decreases expression
ISO Amiodarone results in increased expression of SQSTM1 mRNA
Amiodarone affects the expression of SQSTM1 mRNA
Amiodarone results in decreased expression of SQSTM1 protein
CTD PMID:19774075 PMID:32651653 PMID:36586010 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression
increases expression
EXP
ISO
Amiodarone results in decreased expression of SREBF1 mRNA
Amiodarone results in increased expression of SREBF1 mRNA
CTD PMID:17202758 PMID:28962527 PMID:32651653 PMID:34259586 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srek1ip1 SREK1-interacting protein 1 increases expression ISO Amiodarone results in increased expression of SREK1IP1 mRNA CTD PMID:19774075 NCBI chr 2:35,975,978...35,999,636
Ensembl chr 2:35,975,989...35,999,636
JBrowse link
G Srm spermidine synthase affects expression EXP Amiodarone affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 5:159,025,875...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srprb SRP receptor subunit beta affects expression EXP Amiodarone affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 8:103,768,685...103,782,632 JBrowse link
G Ss18l1 SS18L1 subunit of BAF chromatin remodeling complex increases expression ISO Amiodarone results in increased expression of SS18L1 mRNA CTD PMID:19774075 NCBI chr 3:167,143,730...167,165,253
Ensembl chr 3:167,143,994...167,165,253
JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression EXP Amiodarone affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
JBrowse link
G St13 ST13, Hsp70 interacting protein affects expression EXP Amiodarone affects the expression of ST13 mRNA CTD PMID:18355885 NCBI chr 7:112,891,007...112,925,727
Ensembl chr 7:112,844,375...112,925,945
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression EXP Amiodarone affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 affects expression EXP Amiodarone affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G Stard5 StAR-related lipid transfer domain containing 5 increases expression ISO Amiodarone results in increased expression of STARD5 mRNA CTD PMID:19774075 NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression ISO Amiodarone results in decreased expression of STAT1 mRNA CTD PMID:35641671 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat2 signal transducer and activator of transcription 2 decreases expression ISO Amiodarone results in decreased expression of STAT2 mRNA CTD PMID:35641671 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967
JBrowse link
G Stbd1 starch binding domain 1 affects expression EXP Amiodarone affects the expression of STBD1 mRNA CTD PMID:18355885 NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443
JBrowse link
G Stk16 serine/threonine kinase 16 increases expression ISO Amiodarone results in increased expression of STK16 mRNA CTD PMID:19774075 NCBI chr 9:76,705,591...76,708,859
Ensembl chr 9:76,705,602...76,708,855
JBrowse link
G Stmn1 stathmin 1 affects expression EXP Amiodarone affects the expression of STMN1 mRNA CTD PMID:18355885 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stum stum, mechanosensory transduction mediator homolog increases expression ISO Amiodarone results in increased expression of STUM mRNA CTD PMID:19774075 NCBI chr13:92,172,175...92,227,205
Ensembl chr13:92,173,544...92,227,213
JBrowse link
G Stx11 syntaxin 11 increases expression ISO Amiodarone results in increased expression of STX11 mRNA CTD PMID:19774075 NCBI chr 1:7,293,427...7,320,060
Ensembl chr 1:7,289,976...7,320,164
JBrowse link
G Stxbp2 syntaxin binding protein 2 increases expression ISO Amiodarone results in increased expression of STXBP2 mRNA CTD PMID:19774075 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:1,689,410...1,700,458
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of SUCLG1 mRNA
Amiodarone results in increased expression of SUCLG1 mRNA
CTD PMID:19483382 PMID:24489787 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600
JBrowse link
G Sulf2 sulfatase 2 increases expression ISO Amiodarone results in increased expression of SULF2 mRNA CTD PMID:24535564 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression ISO Amiodarone results in increased expression of SULT2A1 protein CTD PMID:23308384 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link
G Surf4 surfeit 4 affects expression EXP Amiodarone affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 3:10,248,360...10,261,537
Ensembl chr 3:10,241,837...10,263,315
JBrowse link
G Svil supervillin increases expression ISO Amiodarone results in increased expression of SVIL mRNA CTD PMID:19774075 NCBI chr17:52,648,502...52,844,114
Ensembl chr17:52,648,502...52,793,404
JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression EXP Amiodarone affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
JBrowse link
G Taf5l1 TATA-box binding protein associated factor 5 like 1 increases expression ISO Amiodarone results in increased expression of TAF5L mRNA CTD PMID:19774075 NCBI chr19:51,991,704...52,011,001
Ensembl chr19:51,991,708...52,011,295
JBrowse link
G Tafazzin tafazzin, phospholipid-lysophospholipid transacylase increases expression ISO Amiodarone results in increased expression of TAFAZZIN mRNA CTD PMID:19774075 PMID:24489787 NCBI chr  X:152,065,539...152,076,178
Ensembl chr  X:152,065,609...152,074,001
JBrowse link
G Tagln transgelin decreases expression ISO Amiodarone results in decreased expression of TAGLN mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tapbpl TAP binding protein-like increases expression ISO Amiodarone results in increased expression of TAPBPL mRNA CTD PMID:19774075 NCBI chr 4:158,021,454...158,028,905 JBrowse link
G Tas2r106 taste receptor, type 2, member 106 increases expression ISO Amiodarone results in increased expression of TAS2R10 mRNA CTD PMID:19774075 NCBI chr 4:165,313,210...165,314,133
Ensembl chr 4:165,313,210...165,314,133
JBrowse link
G Tbx3 T-box transcription factor 3 increases expression ISO Amiodarone results in increased expression of TBX3 mRNA CTD PMID:23397585 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tbx4 T-box transcription factor 4 increases expression ISO Amiodarone results in increased expression of TBX4 mRNA CTD PMID:19774075 NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825
JBrowse link
G Tbxas1 thromboxane A synthase 1 increases expression EXP Amiodarone results in increased expression of TBXAS1 mRNA CTD PMID:22291062 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096
JBrowse link
G Tcaim T cell activation inhibitor, mitochondrial increases expression ISO Amiodarone results in increased expression of TCAIM mRNA CTD PMID:19774075 NCBI chr 8:122,414,827...122,446,105
Ensembl chr 8:122,414,818...122,446,092
JBrowse link
G Tcf20 transcription factor 20 increases expression ISO Amiodarone results in increased expression of TCF20 mRNA CTD PMID:19774075 NCBI chr 7:113,953,449...114,104,166
Ensembl chr 7:113,954,089...114,051,839
JBrowse link
G Tcf7 transcription factor 7 increases expression ISO Amiodarone results in increased expression of TCF7 mRNA CTD PMID:19774075 NCBI chr10:36,423,443...36,454,350
Ensembl chr10:36,423,445...36,453,535
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase increases expression ISO Amiodarone results in increased expression of TDO2 mRNA CTD PMID:19774075 NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
JBrowse link
G Tef TEF transcription factor, PAR bZIP family member increases expression ISO Amiodarone results in increased expression of TEF mRNA CTD PMID:19774075 NCBI chr 7:113,317,191...113,341,783
Ensembl chr 7:113,317,283...113,341,783
JBrowse link
G Tenm3 teneurin transmembrane protein 3 increases expression ISO Amiodarone results in increased expression of TENM3 mRNA CTD PMID:24535564 NCBI chr16:41,251,909...43,978,594
Ensembl chr16:41,252,182...43,978,594
JBrowse link
G Terf1 telomeric repeat binding factor 1 increases expression ISO Amiodarone results in increased expression of TERF1 mRNA CTD PMID:19774075 NCBI chr 5:3,443,103...3,472,377
Ensembl chr 5:3,443,106...3,472,340
JBrowse link
G Tex261 testis expressed 261 affects expression EXP Amiodarone affects the expression of TEX261 mRNA CTD PMID:18355885 NCBI chr 4:116,253,547...116,260,730
Ensembl chr 4:116,244,600...116,260,253
JBrowse link
G Tf transferrin decreases expression
increases expression
EXP
ISO
Amiodarone results in decreased expression of TF protein
Amiodarone results in increased expression of TF mRNA
CTD PMID:16538043 PMID:36586010 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tfap2c transcription factor AP-2 gamma increases expression ISO Amiodarone results in increased expression of TFAP2C mRNA CTD PMID:19774075 NCBI chr 3:161,315,114...161,322,998
Ensembl chr 3:161,315,031...161,322,995
JBrowse link
G Tfb1m transcription factor B1, mitochondrial increases expression ISO Amiodarone results in increased expression of TFB1M mRNA CTD PMID:24489787 NCBI chr 1:44,115,240...44,161,737
Ensembl chr 1:44,119,166...44,161,709
JBrowse link
G Tfeb transcription factor EB multiple interactions
affects localization
ISO TFEB protein inhibits the reaction [Amiodarone results in increased import of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]
Amiodarone affects the localization of TFEB protein
CTD PMID:25881747 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
JBrowse link
G Tff3 trefoil factor 3 decreases expression ISO Amiodarone results in decreased expression of TFF3 mRNA CTD PMID:24535564 NCBI chr20:9,193,259...9,197,969
Ensembl chr20:9,193,262...9,198,054
JBrowse link
G Tfg trafficking from ER to golgi regulator increases expression ISO Amiodarone results in increased expression of TFG mRNA CTD PMID:19774075 NCBI chr11:43,885,542...43,911,976
Ensembl chr11:43,885,661...43,911,976
JBrowse link
G Tg thyroglobulin decreases expression
increases expression
multiple interactions
ISO
EXP
Amiodarone results in decreased expression of TG mRNA; Amiodarone results in decreased expression of TG protein
Amiodarone results in increased expression of TG mRNA
4-phenylbutyric acid inhibits the reaction [Amiodarone results in decreased expression of TG protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Amiodarone results in decreased expression of TG protein]
CTD PMID:18020914 PMID:25295624 PMID:27197836 NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
EXP Amiodarone results in increased expression of TGFB1 mRNA; Amiodarone results in increased expression of TGFB1 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein]
CTD PMID:11597910 PMID:34590760 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression EXP Amiodarone affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
JBrowse link
G Tgoln2 trans-golgi network protein 2 increases expression ISO Amiodarone results in increased expression of TGOLN2 mRNA CTD PMID:23397585 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
JBrowse link
G Thnsl2 threonine synthase-like 2 affects expression EXP Amiodarone affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
JBrowse link
G Thra thyroid hormone receptor alpha affects binding
decreases expression
increases activity
multiple interactions
increases expression
ISO
EXP
Amiodarone binds to THRA protein
Amiodarone results in decreased expression of THRA mRNA alternative form
Amiodarone results in increased activity of THRA protein
[Isoproterenol co-treated with Amiodarone] results in increased expression of THRA mRNA alternative form
Amiodarone results in increased expression of THRA mRNA alternative form
CTD PMID:7598731 PMID:10445678 PMID:11806713 PMID:17535870 PMID:22015988 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta affects binding
multiple interactions
decreases expression
increases expression
ISO
EXP
Amiodarone binds to THRB protein
Amiodarone inhibits the reaction [Triiodothyronine results in increased activity of THRB protein]
Amiodarone results in decreased expression of THRB mRNA alternative form
[Isoproterenol co-treated with Amiodarone] results in increased expression of THRB mRNA alternative form; Amiodarone inhibits the reaction [Isoproterenol results in increased expression of THRB mRNA alternative form]
Amiodarone results in increased expression of THRB mRNA
CTD PMID:7598731 PMID:10445678 PMID:11806713 PMID:17535870 PMID:19774075 More... NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Thrsp thyroid hormone responsive increases expression
multiple interactions
EXP Amiodarone results in increased expression of THRSP mRNA
Triiodothyronine inhibits the reaction [Amiodarone results in increased expression of THRSP mRNA]
CTD PMID:2721112 PMID:17991464 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Timm10b translocase of inner mitochondrial membrane 10B affects expression EXP Amiodarone affects the expression of TIMM10B mRNA CTD PMID:18355885 NCBI chr 1:159,980,525...159,983,371
Ensembl chr 1:159,980,484...159,981,642
JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 increases expression ISO Amiodarone results in increased expression of TIMM13 mRNA CTD PMID:19774075 NCBI chr 7:8,809,069...8,810,172
Ensembl chr 7:8,809,058...8,809,910
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A increases expression ISO Amiodarone results in increased expression of TIMM17A mRNA CTD PMID:19774075 NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression EXP Amiodarone affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:78,314,900...78,319,362
Ensembl chr18:78,314,909...78,319,454
JBrowse link
G Tinag tubulointerstitial nephritis antigen increases expression ISO Amiodarone results in increased expression of TINAG mRNA CTD PMID:19774075 NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
JBrowse link
G Tjp3 tight junction protein 3 decreases expression EXP Amiodarone results in decreased expression of TJP3 mRNA CTD PMID:17991464 NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
JBrowse link
G Tkfc triokinase and FMN cyclase affects expression EXP Amiodarone affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
JBrowse link
G Tktl1 transketolase-like 1 increases expression ISO Amiodarone results in increased expression of TKTL1 mRNA CTD PMID:19774075 NCBI chr  X:151,954,261...151,987,208
Ensembl chr  X:151,954,175...151,987,208
JBrowse link
G Tlcd1 TLC domain containing 1 decreases expression EXP Amiodarone results in decreased expression of TLCD1 mRNA CTD PMID:17991464 NCBI chr10:63,074,469...63,076,502
Ensembl chr10:63,074,469...63,076,501
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression EXP Amiodarone results in increased expression of TM7SF2 mRNA CTD PMID:22291062 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression EXP Amiodarone affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 increases expression ISO Amiodarone results in increased expression of TMCC2 mRNA CTD PMID:19774075 NCBI chr13:43,794,029...43,831,716
Ensembl chr13:43,794,029...43,831,716
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression EXP Amiodarone affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr13:79,460,229...79,483,557
Ensembl chr13:79,460,135...79,483,555
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression EXP Amiodarone affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr12:32,052,542...32,061,628
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression EXP Amiodarone affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
JBrowse link
G Tmem123 transmembrane protein 123 affects expression EXP Amiodarone affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 8:4,922,077...4,952,228
Ensembl chr 8:4,922,098...4,952,224
JBrowse link
G Tmem161b transmembrane protein 161B increases expression ISO Amiodarone results in increased expression of TMEM161B mRNA CTD PMID:19774075 NCBI chr 2:14,714,451...14,793,809
Ensembl chr 2:14,715,701...14,793,803
JBrowse link
G Tmem68 transmembrane protein 68 increases expression ISO Amiodarone results in increased expression of TMEM68 mRNA CTD PMID:19774075 NCBI chr 5:16,494,054...16,524,842
Ensembl chr 5:16,494,276...16,524,569
JBrowse link
G Tmem97 transmembrane protein 97 affects expression EXP Amiodarone affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
JBrowse link
G Tmem98 transmembrane protein 98 increases expression ISO Amiodarone results in increased expression of TMEM98 mRNA CTD PMID:24535564 NCBI chr10:65,796,173...65,807,082
Ensembl chr10:65,796,145...65,807,079
JBrowse link
G Tmlhe trimethyllysine hydroxylase, epsilon increases expression ISO Amiodarone results in increased expression of TMLHE mRNA CTD PMID:19774075 NCBI chr20:91,234...138,942
Ensembl chr20:91,272...140,386
JBrowse link
G Tmprss9 transmembrane serine protease 9 increases expression ISO Amiodarone results in increased expression of TMPRSS9 mRNA CTD PMID:19774075 NCBI chr 7:8,810,321...8,831,177
Ensembl chr 7:8,810,320...8,831,177
JBrowse link
G Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 increases expression ISO Amiodarone results in increased expression of TMTC2 mRNA CTD PMID:24535564 NCBI chr 7:40,392,377...40,806,685
Ensembl chr 7:40,394,220...40,807,298
JBrowse link
G Tmub2 transmembrane and ubiquitin-like domain containing 2 increases expression ISO Amiodarone results in increased expression of TMUB2 mRNA CTD PMID:19774075 NCBI chr10:87,238,543...87,242,968
Ensembl chr10:87,238,548...87,242,779
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO
EXP
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of TNF protein; [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Amiodarone inhibits the reaction [CRP protein results in increased expression of TNF protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]
Amiodarone results in increased expression of TNF mRNA; Amiodarone results in increased expression of TNF protein
[Amiodarone co-treated with TNF protein] results in increased activity of CASP9 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of TNF protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of TNF protein]; Olmesartan Medoxomil inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of TNF protein]; TNF protein affects the susceptibility to [Amiodarone co-treated with Lipopolysaccharides]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of TNF protein]
CTD PMID:18974383 PMID:19225199 PMID:19362101 PMID:21984482 PMID:22785256 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Amiodarone results in increased expression of TNFAIP3 mRNA CTD PMID:19774075 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases response to substance
multiple interactions
ISO Amiodarone results in increased susceptibility to TNFSF10 protein
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP3 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP9 protein; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of PARP1 protein
CTD PMID:21292685 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnnt1 troponin T1, slow skeletal type increases expression ISO Amiodarone results in increased expression of TNNT1 mRNA CTD PMID:19774075 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
JBrowse link
G Tnrc6a trinucleotide repeat containing adaptor 6A increases expression ISO Amiodarone results in increased expression of TNRC6A mRNA CTD PMID:19774075 NCBI chr 1:177,561,898...177,715,669
Ensembl chr 1:177,646,030...177,715,660
JBrowse link
G Tom1l1 target of myb1 like 1 membrane trafficking protein increases expression ISO Amiodarone results in increased expression of TOM1L1 mRNA CTD PMID:19774075 NCBI chr10:75,464,577...75,508,304
Ensembl chr10:75,464,577...75,508,250
JBrowse link
G Top1mt DNA topoisomerase I mitochondrial increases expression ISO Amiodarone results in increased expression of TOP1MT mRNA CTD PMID:24489787 NCBI chr 7:107,338,092...107,368,125
Ensembl chr 7:107,342,527...107,366,049
JBrowse link
G Tp53 tumor protein p53 decreases expression ISO Amiodarone results in decreased expression of TP53 mRNA CTD PMID:35641671 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpo thyroid peroxidase decreases expression
increases expression
ISO
EXP
Amiodarone results in decreased expression of TPO mRNA
Amiodarone results in increased expression of TPO mRNA
CTD PMID:18020914 PMID:27197836 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
JBrowse link
G Tpst1 tyrosylprotein sulfotransferase 1 decreases expression ISO Amiodarone results in decreased expression of TPST1 mRNA CTD PMID:24535564 NCBI chr12:26,544,536...26,605,706
Ensembl chr12:26,544,536...26,605,704
JBrowse link
G Trex1 three prime repair exonuclease 1 increases expression ISO Amiodarone results in increased expression of TREX1 mRNA CTD PMID:19774075 NCBI chr 8:109,706,613...109,707,913
Ensembl chr 8:109,706,613...109,708,796
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Amiodarone results in increased expression of TRIB3 mRNA CTD PMID:19774075 PMID:24535564 PMID:36586010 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Trim36 tripartite motif-containing 36 increases expression ISO Amiodarone results in increased expression of TRIM36 mRNA CTD PMID:19774075 NCBI chr18:38,859,604...38,912,859
Ensembl chr18:38,861,018...38,912,859
JBrowse link
G Trmt10b tRNA methyltransferase 10B increases expression ISO Amiodarone results in increased expression of TRMT10B mRNA CTD PMID:19774075 NCBI chr 5:59,548,845...59,572,529
Ensembl chr 5:59,548,869...59,572,526
JBrowse link
G Trmu tRNA mitochondrial 2-thiouridylase increases expression ISO Amiodarone results in increased expression of TRMU mRNA CTD PMID:24489787 NCBI chr 7:116,969,750...116,987,704
Ensembl chr 7:116,969,756...116,986,355
JBrowse link
G Trnt1 tRNA nucleotidyl transferase 1 increases expression ISO Amiodarone results in increased expression of TRNT1 mRNA CTD PMID:19774075 NCBI chr 4:139,681,115...139,703,611
Ensembl chr 4:139,680,858...139,703,611
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 increases expression ISO Amiodarone results in increased expression of TRPV2 mRNA CTD PMID:19774075 NCBI chr10:47,265,524...47,294,263
Ensembl chr10:47,272,931...47,294,260
JBrowse link
G Tsga10 testis specific 10 increases expression ISO Amiodarone results in increased expression of TSGA10 mRNA CTD PMID:19774075 NCBI chr 9:39,991,203...40,098,259
Ensembl chr 9:39,991,830...40,098,232
JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression ISO
EXP
Amiodarone results in increased expression of TSHB protein
Amiodarone results in increased expression of TSHB mRNA; Amiodarone results in increased expression of TSHB protein
CTD PMID:1860199 PMID:3427795 PMID:12538616 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression ISO Amiodarone results in increased expression of TSLP mRNA CTD PMID:19774075 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
JBrowse link
G Tspyl2 TSPY-like 2 increases expression ISO Amiodarone results in increased expression of TSPYL2 mRNA CTD PMID:19774075 NCBI chr  X:21,439,478...21,445,208
Ensembl chr  X:21,439,478...21,445,089
JBrowse link
G Ttbk2 tau tubulin kinase 2 increases expression ISO Amiodarone results in increased expression of TTBK2 mRNA CTD PMID:19774075 NCBI chr 3:107,691,123...107,802,911
Ensembl chr 3:107,697,340...107,803,223
JBrowse link
G Ttll3 tubulin tyrosine ligase like 3 increases expression ISO Amiodarone results in increased expression of TTLL3 mRNA CTD PMID:19774075 NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO Amiodarone results in decreased expression of TUBA1A mRNA CTD PMID:27015953 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
JBrowse link
G Tusc3 tumor suppressor candidate 3 increases expression ISO Amiodarone results in increased expression of TUSC3 mRNA CTD PMID:19774075 NCBI chr16:53,196,195...53,345,241
Ensembl chr16:53,196,195...53,344,781
JBrowse link
G Txn1 thioredoxin 1 affects expression EXP Amiodarone affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression EXP Amiodarone affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression EXP Amiodarone affects the expression of UBA52 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 increases expression ISO Amiodarone results in increased expression of UBE2D2 mRNA CTD PMID:19774075 NCBI chr18:27,364,325...27,406,322
Ensembl chr18:27,364,303...27,406,181
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 increases expression ISO Amiodarone results in increased expression of UBE2D3 mRNA CTD PMID:19774075 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP Amiodarone affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ubxn10 UBX domain protein 10 increases expression ISO Amiodarone results in increased expression of UBXN10 mRNA CTD PMID:19774075 NCBI chr 5:150,953,772...150,959,608
Ensembl chr 5:150,950,731...150,959,744
JBrowse link
G Ubxn11 UBX domain protein 11 increases expression ISO Amiodarone results in increased expression of UBXN11 mRNA CTD PMID:19774075 NCBI chr 5:146,329,666...146,353,529
Ensembl chr 5:146,329,842...146,353,526
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 affects expression EXP Amiodarone affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression EXP Amiodarone affects the expression of UGT1A1 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2a1 UDP glucuronosyltransferase family 2 member A1 affects expression EXP Amiodarone affects the expression of UGT2A1 mRNA CTD PMID:18355885 NCBI chr14:20,521,018...20,545,934
Ensembl chr14:20,517,951...20,545,531
JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 affects expression EXP Amiodarone affects the expression of UGT2B1 mRNA CTD PMID:18355885 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ulk3 unc-51 like kinase 3 increases expression ISO Amiodarone results in increased expression of ULK3 mRNA CTD PMID:19774075 NCBI chr 8:57,992,396...58,000,220
Ensembl chr 8:57,992,723...57,999,467
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression EXP Amiodarone affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750
JBrowse link
G Usf1 upstream transcription factor 1 increases expression ISO Amiodarone results in increased expression of USF1 mRNA CTD PMID:19774075 NCBI chr13:83,845,230...83,854,875
Ensembl chr13:83,822,035...83,854,885
JBrowse link
G Usp2 ubiquitin specific peptidase 2 increases expression ISO Amiodarone results in increased expression of USP2 mRNA CTD PMID:19774075 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Usp25 ubiquitin specific peptidase 25 increases expression ISO Amiodarone results in increased expression of USP25 mRNA CTD PMID:19774075 NCBI chr11:15,603,654...15,711,356
Ensembl chr11:15,603,881...15,711,348
JBrowse link
G Uts2 urotensin 2 increases expression ISO Amiodarone results in increased expression of UTS2 mRNA CTD PMID:19774075 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 increases expression ISO Amiodarone results in increased expression of VCAM1 mRNA CTD PMID:19774075 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
G Vcan versican affects expression
multiple interactions
ISO Amiodarone affects the expression of VCAN protein alternative form
Amiodarone affects the reaction [VCAN protein alternative form affects the expression of SNAI1 protein]; Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein]
CTD PMID:26515726 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
JBrowse link
G Vdac2 voltage-dependent anion channel 2 increases expression ISO Amiodarone results in increased expression of VDAC2 mRNA CTD PMID:24489787 NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Amiodarone results in increased expression of VEGFA mRNA CTD PMID:19774075 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of VIM mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of VIM protein]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of VIM mRNA]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of VIM protein] CTD PMID:31071512 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vldlr very low density lipoprotein receptor decreases expression ISO Amiodarone results in decreased expression of VLDLR mRNA CTD PMID:28962527 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
JBrowse link
G Vmac vimentin-type intermediate filament associated coiled-coil protein increases expression ISO Amiodarone results in increased expression of VMAC mRNA CTD PMID:19774075 NCBI chr 9:1,546,747...1,550,417
Ensembl chr 9:1,546,747...1,549,771
JBrowse link
G Vnn1 vanin 1 affects expression
increases expression
EXP
ISO
Amiodarone affects the expression of VNN1 mRNA
Amiodarone results in increased expression of VNN1 mRNA
CTD PMID:19483382 PMID:24535564 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes increases expression ISO Amiodarone results in increased expression of VPS11 mRNA CTD PMID:19774075 NCBI chr 8:44,684,129...44,698,568
Ensembl chr 8:44,684,127...44,698,568
JBrowse link
G Vps13b vacuolar protein sorting 13 homolog B increases expression ISO Amiodarone results in increased expression of VPS13B mRNA CTD PMID:19774075 NCBI chr 7:66,557,862...67,128,429
Ensembl chr 7:66,558,471...67,128,429
JBrowse link
G Vps16 VPS16 core subunit of CORVET and HOPS complexes increases expression ISO Amiodarone results in increased expression of VPS16 mRNA CTD PMID:19774075 NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441
JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 decreases expression EXP Amiodarone results in decreased expression of VWA1 mRNA CTD PMID:17991464 NCBI chr 5:166,377,451...166,382,784
Ensembl chr 5:166,377,455...166,382,637
JBrowse link
G Wdr26 WD repeat domain 26 affects expression EXP Amiodarone affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Amiodarone results in increased expression of WIPI1 mRNA CTD PMID:15342952 PMID:17567588 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 increases expression ISO Amiodarone results in increased expression of WNK1 mRNA CTD PMID:19774075 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
G Wtap WT1 associated protein increases expression ISO Amiodarone results in increased expression of WTAP mRNA CTD PMID:19774075 NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065
JBrowse link
G Xbp1 X-box binding protein 1 increases expression
increases splicing
multiple interactions
decreases expression
affects localization
ISO Amiodarone results in increased expression of XBP1 mRNA
Amiodarone results in increased splicing of XBP1 mRNA
4-phenylbutyric acid inhibits the reaction [[Amiodarone results in increased splicing of XBP1 mRNA] which results in increased expression of XBP1 mRNA alternative form]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of XBP1 mRNA]; [Amiodarone results in increased splicing of XBP1 mRNA] which results in increased expression of XBP1 mRNA alternative form
Amiodarone results in decreased expression of XBP1 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA]
Amiodarone affects the localization of XBP1 protein
CTD PMID:19774075 PMID:25295624 PMID:28962527 PMID:35641671 PMID:36586010 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xk X-linked Kx blood group antigen, Kell and VPS13A binding protein increases expression ISO Amiodarone results in increased expression of XK mRNA CTD PMID:19774075 NCBI chr  X:13,436,412...13,472,830
Ensembl chr  X:13,436,418...13,472,830
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase 2 increases expression ISO Amiodarone results in increased expression of XPNPEP2 mRNA CTD PMID:19774075 NCBI chr  X:127,287,765...127,317,036
Ensembl chr  X:127,287,979...127,317,223
JBrowse link
G Xpo7 exportin 7 decreases expression EXP Amiodarone results in decreased expression of XPO7 mRNA CTD PMID:17991464 NCBI chr15:45,742,053...45,828,050
Ensembl chr15:45,742,053...45,828,050
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 increases expression ISO Amiodarone results in increased expression of XRCC5 mRNA CTD PMID:24489787 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma affects expression EXP Amiodarone affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Zbed3 zinc finger, BED-type containing 3 increases expression ISO Amiodarone results in increased expression of ZBED3 mRNA CTD PMID:19774075 NCBI chr 2:26,587,620...26,600,177
Ensembl chr 2:26,587,572...26,600,386
JBrowse link
G Zbtb49 zinc finger and BTB domain containing 49 increases expression ISO Amiodarone results in increased expression of ZBTB49 mRNA CTD PMID:19774075 NCBI chr14:72,590,692...72,612,404
Ensembl chr14:72,590,708...72,612,404
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 increases expression ISO Amiodarone results in increased expression of ZC3HAV1 mRNA CTD PMID:19774075 NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428
JBrowse link
G Zdhhc15 zinc finger DHHC-type palmitoyltransferase 15 increases expression ISO Amiodarone results in increased expression of ZDHHC15 mRNA CTD PMID:19774075 NCBI chr  X:69,568,086...69,701,756
Ensembl chr  X:69,574,124...69,701,756
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 affects expression EXP Amiodarone affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
JBrowse link
G Zfp13 zinc finger protein 13 increases expression ISO Amiodarone results in increased expression of ZNF205 mRNA CTD PMID:19774075 NCBI chr10:12,615,455...12,623,615
Ensembl chr10:12,615,190...12,623,615
JBrowse link
G Zfp36 zinc finger protein 36 increases expression ISO Amiodarone results in increased expression of ZFP36 mRNA CTD PMID:19774075 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Zfp420 zinc finger protein 420 increases expression ISO Amiodarone results in increased expression of ZNF420 mRNA CTD PMID:19774075 NCBI chr 1:85,092,810...85,143,682
Ensembl chr 1:85,093,085...85,106,693
Ensembl chr 1:85,093,085...85,106,693
JBrowse link
G Zfp560 zinc finger protein 560 increases expression ISO Amiodarone results in increased expression of ZNF121 mRNA CTD PMID:19774075 NCBI chr 8:18,900,142...18,914,444
Ensembl chr 8:18,900,528...18,914,442
JBrowse link
G Zfp592 zinc finger protein 592 increases expression ISO Amiodarone results in increased expression of ZNF592 mRNA CTD PMID:19774075 NCBI chr 1:134,951,286...135,002,443
Ensembl chr 1:134,967,783...135,002,443
JBrowse link
G Zfp683 zinc finger protein 683 increases expression ISO Amiodarone results in increased expression of ZNF683 mRNA CTD PMID:19774075 NCBI chr 5:146,277,972...146,285,856
Ensembl chr 5:146,278,978...146,285,000
JBrowse link
G Zfp703 zinc finger protein 703 increases expression ISO Amiodarone results in increased expression of ZNF703 mRNA CTD PMID:19774075 NCBI chr16:65,076,507...65,080,677
Ensembl chr16:65,076,507...65,080,677
JBrowse link
G Zfp704 zinc finger protein 704 increases expression ISO Amiodarone results in increased expression of ZNF704 mRNA CTD PMID:19774075 NCBI chr 2:92,171,804...92,356,059
Ensembl chr 2:92,171,496...92,351,282
JBrowse link
G Zfp710 zinc finger protein 710 increases expression ISO Amiodarone results in increased expression of ZNF710 mRNA CTD PMID:19774075 NCBI chr 1:133,966,256...134,036,593
Ensembl chr 1:134,024,267...134,036,601
JBrowse link
G Zfp771 zinc finger protein 771 increases expression ISO Amiodarone results in increased expression of ZNF771 mRNA CTD PMID:19774075 NCBI chr 1:181,864,035...181,875,136
Ensembl chr 1:181,864,219...181,875,141
JBrowse link
G Zmynd10 zinc finger, MYND-type containing 10 increases expression ISO Amiodarone results in increased expression of ZMYND10 mRNA CTD PMID:19774075 NCBI chr 8:108,220,386...108,224,745
Ensembl chr 8:108,220,386...108,224,744
JBrowse link
G Znf624l zinc finger protein 624 like increases expression ISO Amiodarone results in increased expression of ZNF624 mRNA CTD PMID:19774075 NCBI chr 7:7,853,363...7,890,995
Ensembl chr 7:7,853,403...7,890,974
JBrowse link
G Znhit2 zinc finger, HIT-type containing 2 increases expression ISO Amiodarone results in increased expression of ZNHIT2 mRNA CTD PMID:19774075 NCBI chr 1:203,354,297...203,355,578
Ensembl chr 1:203,354,138...203,355,636
JBrowse link
G Zscan20 zinc finger and SCAN domain containing 20 increases expression ISO Amiodarone results in increased expression of ZSCAN20 mRNA CTD PMID:19774075 NCBI chr 5:140,926,596...140,956,285
Ensembl chr 5:140,930,689...140,956,336
JBrowse link
G Zwint ZW10 interacting kinetochore protein affects expression EXP Amiodarone affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
G Zxda zinc finger, X-linked, duplicated A increases expression ISO Amiodarone results in increased expression of ZXDA mRNA CTD PMID:19774075 NCBI chr  X:59,760,871...59,766,010
Ensembl chr  X:59,763,210...59,765,903
JBrowse link

Term paths to the root
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  CHEBI ontology 19917
    role 19887
      application 19729
        pharmaceutical 19563
          drug 19563
            cardiovascular drug 8644
              amiodarone 1240
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  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    main group molecular entity 19855
                      s-block molecular entity 19686
                        hydrogen molecular entity 19667
                          hydrides 19173
                            inorganic hydride 18184
                              pnictogen hydride 18174
                                nitrogen hydride 18087
                                  azane 17893
                                    ammonia 17892
                                      organic amino compound 17892
                                        tertiary amino compound 10159
                                          amiodarone 1240
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