Slc25a25 (solute carrier family 25 member 25) - Rat Genome Database

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Gene: Slc25a25 (solute carrier family 25 member 25) Rattus norvegicus
Analyze
Symbol: Slc25a25
Name: solute carrier family 25 member 25
RGD ID: 628666
Description: Predicted to enable ATP:phosphate antiporter activity. Predicted to be involved in ADP transport and ATP transport. Predicted to act upstream of or within several processes, including response to activity; response to dietary excess; and response to food. Located in mitochondrion. Orthologous to human SLC25A25 (solute carrier family 25 member 25); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,2',4,5'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP-Mg/Pi carrier; calcium-binding mitochondrial carrier protein SCaMC-2; Mcsc; mitochondrial adenyl nucleotide antiporter SLC25A25; mitochondrial ATP-Mg/Pi carrier protein; mitochondrial Ca2+-dependent solute carrier; mitochondrial calcium-dependent solute carrier; Pcscl; peroxisomal Ca(2+)-dependent solute carrier-like protein; peroxisomal Ca-dependent solute carrier-like protein; SCaMC-2; short calcium-binding mitochondrial carrier protein 2; small calcium-binding mitochondrial carrier protein 2; solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,106,448 - 36,139,812 (-)NCBIGRCr8
mRatBN7.2315,708,702 - 15,742,195 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,708,703 - 15,742,216 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,777,546 - 18,787,673 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,362,543 - 27,372,674 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,613,291 - 25,623,413 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,442,396 - 11,476,186 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,442,397 - 11,452,529 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,791,266 - 16,825,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,539,415 - 11,549,538 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,435,787 - 11,445,910 (-)NCBI
Celera310,451,575 - 10,461,792 (-)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',4,5'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (EXP)
bromobenzene  (EXP)
cadmium dichloride  (EXP)
cadmium sulfate  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
chlorpyrifos  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
corn oil  (EXP)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
diquat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (EXP)
gentamycin  (EXP)
indole-3-methanol  (EXP)
inulin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
mercury dichloride  (EXP)
methamphetamine  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
monosodium L-glutamate  (ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
okadaic acid  (ISO)
organophosphorus compound  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phorone  (EXP)
pirinixic acid  (ISO)
progesterone  (EXP)
propiconazole  (EXP)
rac-lactic acid  (ISO)
sevoflurane  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (EXP)
tamoxifen  (ISO)
teriflunomide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
triadimefon  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Identification of a novel human subfamily of mitochondrial carriers with calcium-binding domains. del Arco A and Satrústegui J, J Biol Chem. 2004 Jun 4;279(23):24701-13. doi: 10.1074/jbc.M401417200. Epub 2004 Mar 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. A novel mitochondrial Ca2+-dependent solute carrier in the liver identified by mRNA differential display. Mashima H, etal., J Biol Chem 2003 Mar 14;278(11):9520-7.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12851217   PMID:18614015   PMID:21296886   PMID:23062354   PMID:23344948   PMID:23376485   PMID:30361391  


Genomics

Comparative Map Data
Slc25a25
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8336,106,448 - 36,139,812 (-)NCBIGRCr8
mRatBN7.2315,708,702 - 15,742,195 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl315,708,703 - 15,742,216 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,777,546 - 18,787,673 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0327,362,543 - 27,372,674 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0325,613,291 - 25,623,413 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0311,442,396 - 11,476,186 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl311,442,397 - 11,452,529 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0316,791,266 - 16,825,049 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,539,415 - 11,549,538 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1311,435,787 - 11,445,910 (-)NCBI
Celera310,451,575 - 10,461,792 (-)NCBICelera
Cytogenetic Map3p11NCBI
SLC25A25
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389128,068,232 - 128,109,245 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9128,068,201 - 128,109,245 (+)EnsemblGRCh38hg38GRCh38
GRCh379130,830,511 - 130,871,524 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369129,870,300 - 129,911,345 (+)NCBINCBI36Build 36hg18NCBI36
Build 349127,940,370 - 127,951,078NCBI
Celera9101,482,501 - 101,523,452 (+)NCBICelera
Cytogenetic Map9q34.11NCBI
HuRef9100,445,708 - 100,486,206 (+)NCBIHuRef
CHM1_19130,982,710 - 131,023,583 (+)NCBICHM1_1
T2T-CHM13v2.09140,276,208 - 140,317,210 (+)NCBIT2T-CHM13v2.0
Slc25a25
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39232,304,499 - 32,341,482 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl232,304,499 - 32,341,457 (-)EnsemblGRCm39 Ensembl
GRCm38232,414,487 - 32,451,470 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl232,414,487 - 32,451,445 (-)EnsemblGRCm38mm10GRCm38
MGSCv37232,270,007 - 32,306,990 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36232,236,489 - 32,273,431 (-)NCBIMGSCv36mm8
Celera232,120,151 - 32,157,130 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map222.09NCBI
Slc25a25
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955419618,979 - 656,189 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955419621,445 - 656,172 (-)NCBIChiLan1.0ChiLan1.0
SLC25A25
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21111,243,799 - 11,284,673 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1911,246,147 - 11,287,021 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0999,188,906 - 99,229,771 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19127,859,948 - 127,900,922 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9127,859,948 - 127,900,922 (+)Ensemblpanpan1.1panPan2
SLC25A25
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1955,358,348 - 55,394,624 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl955,360,043 - 55,394,519 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha954,553,071 - 54,588,912 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0956,285,169 - 56,316,835 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1955,040,512 - 55,076,587 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0955,355,242 - 55,391,319 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0955,446,944 - 55,482,811 (-)NCBIUU_Cfam_GSD_1.0
Slc25a25
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947195,892,611 - 195,927,737 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648715,661,079 - 15,696,406 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648715,661,133 - 15,696,267 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A25
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1268,531,752 - 268,576,994 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11268,531,752 - 268,575,195 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21302,558,673 - 302,565,658 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21302,453,222 - 302,453,476 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A25
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11210,017,775 - 10,059,013 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1210,017,755 - 10,035,476 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660796,165,921 - 6,208,553 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a25
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247607,515,764 - 7,550,810 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247607,516,910 - 7,550,897 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc25a25
238 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:257
Count of miRNA genes:167
Interacting mature miRNAs:202
Transcripts:ENSRNOT00000020206
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)31043430624512004Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
1558657Cm43Cardiac mass QTL 436.63e-08heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat

Markers in Region
UniSTS:547045  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2315,708,940 - 15,709,865 (+)MAPPERmRatBN7.2
Rnor_6.0311,442,635 - 11,443,559NCBIRnor6.0
Rnor_5.0316,791,505 - 16,792,429UniSTSRnor5.0
Celera310,451,814 - 10,452,738UniSTS
Cytogenetic Map3p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001431501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001431509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063283101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AY043169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020206   ⟹   ENSRNOP00000020206
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,708,703 - 15,718,835 (-)Ensembl
Rnor_6.0 Ensembl311,442,397 - 11,452,529 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099400   ⟹   ENSRNOP00000092861
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,708,703 - 15,720,289 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000102915   ⟹   ENSRNOP00000092658
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,708,703 - 15,720,874 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104155   ⟹   ENSRNOP00000091438
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,708,703 - 15,725,977 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107630   ⟹   ENSRNOP00000093449
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,708,703 - 15,742,216 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115249   ⟹   ENSRNOP00000087701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl315,708,703 - 15,725,977 (-)Ensembl
RefSeq Acc Id: NM_145677   ⟹   NP_663710
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,116,581 (-)NCBI
mRatBN7.2315,708,702 - 15,718,835 (-)NCBI
Rnor_6.0311,442,396 - 11,452,529 (-)NCBI
Rnor_5.0316,791,266 - 16,825,049 (-)NCBI
RGSC_v3.4311,539,415 - 11,549,538 (-)RGD
Celera310,451,575 - 10,461,792 (-)RGD
Sequence:
RefSeq Acc Id: XM_006233931   ⟹   XP_006233993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,139,812 (-)NCBI
mRatBN7.2315,708,702 - 15,742,195 (-)NCBI
Rnor_6.0311,442,396 - 11,476,186 (-)NCBI
Rnor_5.0316,791,266 - 16,825,049 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233932   ⟹   XP_006233994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,139,812 (-)NCBI
mRatBN7.2315,708,702 - 15,742,193 (-)NCBI
Rnor_6.0311,442,396 - 11,476,185 (-)NCBI
Rnor_5.0316,791,266 - 16,825,049 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233933   ⟹   XP_006233995
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,124,023 (-)NCBI
mRatBN7.2315,708,702 - 15,725,732 (-)NCBI
Rnor_6.0311,442,396 - 11,460,298 (-)NCBI
Rnor_5.0316,791,266 - 16,825,049 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233934   ⟹   XP_006233996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,124,023 (-)NCBI
mRatBN7.2315,708,702 - 15,725,732 (-)NCBI
Rnor_6.0311,442,396 - 11,460,297 (-)NCBI
Rnor_5.0316,791,266 - 16,825,049 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233935   ⟹   XP_006233997
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,118,267 (-)NCBI
mRatBN7.2315,708,702 - 15,719,320 (-)NCBI
Rnor_6.0311,442,396 - 11,453,058 (-)NCBI
Rnor_5.0316,791,266 - 16,825,049 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017591471   ⟹   XP_017446960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,124,023 (-)NCBI
mRatBN7.2315,708,702 - 15,726,223 (-)NCBI
Rnor_6.0311,442,396 - 11,460,296 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063283100   ⟹   XP_063139170
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,121,513 (-)NCBI
RefSeq Acc Id: XM_063283101   ⟹   XP_063139171
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8336,106,448 - 36,121,508 (-)NCBI
RefSeq Acc Id: NP_663710   ⟸   NM_145677
- UniProtKB: Q8K3P6 (UniProtKB/Swiss-Prot),   A6JU65 (UniProtKB/TrEMBL),   A0A8I6AHU5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233993   ⟸   XM_006233931
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006233994   ⟸   XM_006233932
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006233995   ⟸   XM_006233933
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006233996   ⟸   XM_006233934
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006233997   ⟸   XM_006233935
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017446960   ⟸   XM_017591471
- Peptide Label: isoform X8
- Sequence:
Ensembl Acc Id: ENSRNOP00000020206   ⟸   ENSRNOT00000020206
Ensembl Acc Id: ENSRNOP00000092658   ⟸   ENSRNOT00000102915
Ensembl Acc Id: ENSRNOP00000092861   ⟸   ENSRNOT00000099400
Ensembl Acc Id: ENSRNOP00000093449   ⟸   ENSRNOT00000107630
Ensembl Acc Id: ENSRNOP00000087701   ⟸   ENSRNOT00000115249
Ensembl Acc Id: ENSRNOP00000091438   ⟸   ENSRNOT00000104155
RefSeq Acc Id: XP_063139170   ⟸   XM_063283100
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AEC3 (UniProtKB/TrEMBL),   A0A8I6AHU5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063139171   ⟸   XM_063283101
- Peptide Label: isoform X7
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8K3P6-F1-model_v2 AlphaFold Q8K3P6 1-469 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691987
Promoter ID:EPDNEW_R2512
Type:initiation region
Name:Slc25a25_1
Description:solute carrier family 25 member 25
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0311,452,542 - 11,452,602EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628666 AgrOrtholog
BioCyc Gene G2FUF-50137 BioCyc
Ensembl Genes ENSRNOG00000014338 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000020206 ENTREZGENE
  ENSRNOT00000099400 ENTREZGENE
  ENSRNOT00000102915 ENTREZGENE
  ENSRNOT00000104155 ENTREZGENE
  ENSRNOT00000107630 ENTREZGENE
  ENSRNOT00000115249 ENTREZGENE
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  Graves_DC UniProtKB/Swiss-Prot
  Mit_carrier UniProtKB/Swiss-Prot
  Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:246771 UniProtKB/Swiss-Prot
NCBI Gene 246771 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 25 UniProtKB/Swiss-Prot
Pfam EF-hand_7 UniProtKB/Swiss-Prot
  EF-hand_8 UniProtKB/Swiss-Prot
  Mito_carr UniProtKB/Swiss-Prot
PhenoGen Slc25a25 PhenoGen
PRINTS GRAVESDC UniProtKB/Swiss-Prot
  MITOCARRIER UniProtKB/Swiss-Prot
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot
  SOLCAR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000014338 RatGTEx
SMART EFh UniProtKB/Swiss-Prot
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot
  SSF47473 UniProtKB/Swiss-Prot
UniProt A0A8I6AEC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFK8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ALC5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GFE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QB89 ENTREZGENE, UniProtKB/TrEMBL
  A6JU64 ENTREZGENE, UniProtKB/TrEMBL
  A6JU65 ENTREZGENE, UniProtKB/TrEMBL
  Q8K3P6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc25a25  solute carrier family 25 member 25  Slc25a25  solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Slc25a25  solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25  Pcscl  peroxisomal Ca-dependent solute carrier-like protein  Symbol and Name updated 1299863 APPROVED
2003-02-27 Pcscl  peroxisomal Ca-dependent solute carrier-like protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in liver and skeletal muscle 633593
gene_expression displays increased expression during hepatocyte differentiation 633593