Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including epithelial cell morphogenesis; establishment of epithelial cell polarity; and eye development. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Is active in glutamatergic synapse and postsynaptic specialization, intracellular component. Human ortholog(s) of this gene implicated in cataract 45. Orthologous to human SIPA1L3 (signal induced proliferation associated 1 like 3); INTERACTS WITH 6-propyl-2-thiouracil; alpha-Zearalanol; amitrole.
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SIPA1L3 mRNA
[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SIPA1L3 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SIPA1L3 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SIPA1L3 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SIPA1L3 mRNA