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Gene: Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1) Rattus norvegicus
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Symbol: Gucy1b1
Name: guanylate cyclase 1 soluble subunit beta 1
Description: Exhibits several functions, including Hsp90 protein binding activity; heme binding activity; and protein heterodimerization activity. Contributes to adenylate cyclase activity and cytidylate cyclase activity. Predicted to be involved in several processes, including cGMP biosynthetic process; cellular response to nitric oxide; and nitric oxide-cGMP-mediated signaling pathway. Localizes to the glutamatergic synapse; guanylate cyclase complex, soluble; and presynaptic active zone cytoplasmic component. Orthologous to human GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GCS-beta-1; GCS-beta-3; guanylate cyclase 1 soluble beta 3; guanylate cyclase 1 soluble subunit beta 3; guanylate cyclase 1, soluble, beta 3; Guanylate cyclase soluble beta 1 (GTP pyrophosphate - lyase); Guanylate cyclase soluble beta 1 (GTP pyrophosphate - lyase) see also D2Mgh17; guanylate cyclase soluble subunit beta-1; guanylate cyclase soluble subunit beta-3; guanylate cyclase, soluble, beta 1; Gucy1b3; MGC93604; SGC; soluble guanylate cyclase small subunit; soluble guanylyl cyclase beta 1 subunit
Orthologs:
Homo sapiens (human) : GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Gucy1b1 (guanylate cyclase 1, soluble, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1)
Canis lupus familiaris (dog) : GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1)
Sus scrofa (pig) : GUCY1B1 (guanylate cyclase 1 soluble subunit beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02180,976,939 - 181,026,001 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02200,384,721 - 200,433,787 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,683,153 - 173,735,298 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12173,633,259 - 173,685,404 (-)NCBI
Celera2161,378,505 - 161,428,991 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gucy1b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2769
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.