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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2769
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gucy1b1
Name: guanylate cyclase 1 soluble subunit beta 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gucy1b1decreases expressionEXP 6480464CTDEstradiol deficiency results in decreased expression of GUCY1B1 mRNA; Estradiol deficiency results in decreased expression of GUCY1B1 proteinPMID:18787021
Gucy1b1affects expressionISOGucy1b1 (Mus musculus)6480464CTDEstradiol affects the expression of GUCY1B1 mRNAPMID:16684588
Gucy1b1multiple interactionsISOGUCY1B1 (Homo sapiens)6480464CTD[Estradiol co-treated with TGFB1 protein] results in decreased expression of GUCY1B1 mRNAPMID:30165855
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