Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1) - Rat Genome Database

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Gene: Gucy1b1 (guanylate cyclase 1 soluble subunit beta 1) Chinchilla lanigera
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Symbol: Gucy1b1
Name: guanylate cyclase 1 soluble subunit beta 1
RGD ID: 8973700
Description: ENCODES a protein that exhibits adenylate cyclase activity (ortholog); cytidylate cyclase activity (ortholog); guanylate cyclase activity (ortholog); INVOLVED IN cGMP biosynthetic process (ortholog); cGMP-mediated signaling (ortholog); nitric oxide-cGMP-mediated signaling pathway (ortholog); PARTICIPATES IN adenine phoshoribosyltransferase deficiency pathway; adenosine monophosphate deaminase deficiency pathway; adenylosuccinate lyase deficiency pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Sporadic Creutzfeldt-Jakob Disease (ortholog); FOUND IN glutamatergic synapse (ortholog); guanylate cyclase complex, soluble (ortholog); presynaptic active zone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: guanylate cyclase 1 soluble subunit beta; guanylate cyclase 1, soluble, beta 3; guanylate cyclase soluble subunit beta-1; Gucy1b3
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,303,242 - 11,351,190 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,303,478 - 11,349,512 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISS annotations to Chinchilla, Squirrel, Bonobo and/or Dog genes from Human gene annotations

Genomics

Comparative Map Data
Gucy1b1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495547111,303,242 - 11,351,190 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495547111,303,478 - 11,349,512 (-)NCBIChiLan1.0ChiLan1.0
GUCY1B1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384155,759,021 - 155,807,811 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl4155,758,992 - 155,807,811 (+)EnsemblGRCh38hg38GRCh38
GRCh374156,680,173 - 156,728,963 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364156,888,572 - 156,947,506 (+)NCBINCBI36hg18NCBI36
Build 344157,037,819 - 157,085,661NCBI
Celera4154,011,736 - 154,060,401 (+)NCBI
Cytogenetic Map4q32.1NCBI
HuRef4152,419,159 - 152,467,730 (+)NCBIHuRef
CHM1_14156,657,845 - 156,706,460 (+)NCBICHM1_1
T2T-CHM13v2.04159,091,817 - 159,140,607 (+)NCBI
Gucy1b1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39381,939,311 - 81,982,018 (-)NCBIGRCm39mm39
GRCm39 Ensembl381,939,313 - 81,981,996 (-)Ensembl
GRCm38382,032,004 - 82,074,711 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl382,032,006 - 82,074,689 (-)EnsemblGRCm38mm10GRCm38
MGSCv37381,835,926 - 81,878,633 (-)NCBIGRCm37mm9NCBIm37
MGSCv36382,117,933 - 82,160,612 (-)NCBImm8
Celera382,056,852 - 82,099,541 (-)NCBICelera
Cytogenetic Map3E3NCBI
Gucy1b1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22167,348,824 - 167,398,983 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2167,348,825 - 167,398,916 (-)Ensembl
Rnor_6.02180,976,939 - 181,026,001 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2180,976,939 - 181,026,024 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02200,384,721 - 200,433,787 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42173,683,153 - 173,735,298 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12173,633,259 - 173,685,404 (-)NCBI
Celera2161,378,505 - 161,428,991 (-)NCBICelera
Cytogenetic Map2q34NCBI
GUCY1B1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14159,942,017 - 159,990,511 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4159,942,017 - 159,990,511 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04148,124,643 - 148,173,315 (+)NCBIMhudiblu_PPA_v0panPan3
GUCY1B1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11553,266,243 - 53,312,109 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1553,265,350 - 53,312,111 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1553,601,513 - 53,647,751 (+)NCBI
ROS_Cfam_1.01553,972,715 - 54,019,854 (+)NCBI
ROS_Cfam_1.0 Ensembl1553,972,653 - 54,020,379 (+)Ensembl
UMICH_Zoey_3.11553,226,121 - 53,272,692 (+)NCBI
UNSW_CanFamBas_1.01553,335,788 - 53,382,060 (+)NCBI
UU_Cfam_GSD_1.01553,649,434 - 53,695,985 (+)NCBI
Gucy1b1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530137,076,967 - 37,119,457 (-)NCBI
SpeTri2.0NW_0049365762,427,451 - 2,469,946 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GUCY1B1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl844,544,179 - 44,604,687 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1844,544,364 - 44,604,690 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2846,747,661 - 46,765,506 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GUCY1B1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17102,332,711 - 102,381,250 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl7102,332,719 - 102,381,251 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603781,990,521 - 82,039,073 (+)NCBIVero_WHO_p1.0
Gucy1b1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248482,462,104 - 2,508,983 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248482,462,240 - 2,508,197 (-)NCBIHetGla_female_1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000016191   ⟹   ENSCLAP00000016027
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547111,303,242 - 11,349,637 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000016192   ⟹   ENSCLAP00000016028
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495547111,305,843 - 11,351,190 (-)Ensembl
RefSeq Acc Id: XM_013522922   ⟹   XP_013378376
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495547111,303,478 - 11,349,512 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013378376 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013378376   ⟸   XM_013522922
- Sequence:
RefSeq Acc Id: ENSCLAP00000016028   ⟸   ENSCLAT00000016192
RefSeq Acc Id: ENSCLAP00000016027   ⟸   ENSCLAT00000016191
Protein Domains
Guanylate cyclase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000011034 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSCLAP00000016027 ENTREZGENE
  ENSCLAP00000016027.1 UniProtKB/TrEMBL
  ENSCLAP00000016028.1 UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000016191 ENTREZGENE
  ENSCLAT00000016191.1 UniProtKB/TrEMBL
  ENSCLAT00000016192.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.450.260 UniProtKB/TrEMBL
  3.30.70.1230 UniProtKB/TrEMBL
  3.90.1520.10 UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/TrEMBL
  H-NOX_domain_sf UniProtKB/TrEMBL
  Heme_NO-bd UniProtKB/TrEMBL
  HNOB_dom_associated UniProtKB/TrEMBL
  HNOB_dom_associated_sf UniProtKB/TrEMBL
  NO_sig/Golgi_transp_ligand-bd UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/TrEMBL
NCBI Gene Gucy1b3 ENTREZGENE
Pfam Guanylate_cyc UniProtKB/TrEMBL
  HNOB UniProtKB/TrEMBL
  HNOBA UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/TrEMBL
SMART CYCc UniProtKB/TrEMBL
Superfamily-SCOP SSF111126 UniProtKB/TrEMBL
  SSF55073 UniProtKB/TrEMBL
UniProt A0A8C2VKB5_CHILA UniProtKB/TrEMBL
  A0A8C2VMA3_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-28 Gucy1b1  guanylate cyclase 1 soluble subunit beta 1  Gucy1b3  guanylate cyclase 1 soluble subunit beta  Symbol and/or name change 5135510 APPROVED
2016-08-03 Gucy1b3  guanylate cyclase 1 soluble subunit beta    guanylate cyclase 1, soluble, beta 3  Symbol and/or name change 5135510 APPROVED