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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2769
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gucy1b1
Name: guanylate cyclase 1 soluble subunit beta 1
Acc ID: CHEBI:7596
Term: nitroprusside
Definition: An iron coordination entity that has formula C5FeN6O.
Chemical ID: MESH:D009599
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD1H-(1, 2, 4)oxadiazolo(4, 3-a)quinoxalin-1-one inhibits the reaction [Nitroprusside results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]], 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide promotes the reaction [Nitroprusside results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]], 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole promotes the reaction [Nitroprusside results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]], Nitroprusside promotes the reaction [3-(2-(2, 2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]], Nitroprusside results in increased activity of [GUCY1A1 protein binds to GUCY1B1 protein]

PMID:12495780, PMID:17050951
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.