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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2769
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gucy1b1
Name: guanylate cyclase 1 soluble subunit beta 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gucy1b1affects expressionEXP 6480464CTDbisphenol A affects the expression of GUCY1B1 mRNAPMID:25181051
Gucy1b1decreases expressionISOGUCY1B1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of GUCY1B1 proteinPMID:31675489
Gucy1b1increases expressionISOGUCY1B1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of GUCY1B1 mRNAPMID:27685785 PMID:29275510
Gucy1b1increases expressionISOGucy1b1 (Mus musculus)6480464CTDbisphenol A results in increased expression of GUCY1B3 mRNAPMID:30951980
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