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RGD ID: 2769
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gucy1b1
Name: guanylate cyclase 1 soluble subunit beta 1
Acc ID: CHEBI:39867
Term: valproic acid
Definition: A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Chemical ID: MESH:D014635
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gucy1b1affects expressionISOGUCY1B1 (Homo sapiens)6480464CTDValproic Acid affects the expression of GUCY1B1 mRNAPMID:25979313
Gucy1b1increases expressionISOGUCY1B1 (Homo sapiens)6480464CTDValproic Acid results in increased expression of GUCY1B1 mRNAPMID:19101580 PMID:23179753 PMID:24383497 PMID:24935251 PMID:27188386
Gucy1b1increases methylationISOGUCY1B1 (Homo sapiens)6480464CTDValproic Acid results in increased methylation of GUCY1B1 genePMID:29154799
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