Fgfr1op2 (FGFR1 oncogene partner 2) - Rat Genome Database

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Gene: Fgfr1op2 (FGFR1 oncogene partner 2) Rattus norvegicus
Analyze
Symbol: Fgfr1op2
Name: FGFR1 oncogene partner 2
RGD ID: 1303233
Description: Predicted to enable identical protein binding activity. Involved in response to wounding. Located in cytoplasm. Orthologous to human FGFR1OP2 (FGFR1 oncogene partner 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FGFR1 oncogene partner 2 homolog; Wit3.0; Wit3.0_alpha; Wit3.0_beta; wound inducible transcript 3.0; wound-inducible transcript 3.0 protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24179,491,602 - 179,512,630 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4179,491,599 - 179,512,630 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4185,777,106 - 185,798,069 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04181,561,631 - 181,582,590 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04180,182,049 - 180,203,008 (+)NCBIRnor_WKY
Rnor_6.04180,887,182 - 180,908,206 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4180,887,182 - 180,908,198 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04245,046,889 - 245,067,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44184,153,022 - 184,173,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14184,398,145 - 184,419,085 (+)NCBI
Celera4167,988,215 - 168,009,154 (+)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Small cytoskeleton-associated molecule, fibroblast growth factor receptor 1 oncogene partner 2/wound inducible transcript-3.0 (FGFR1OP2/wit3.0), facilitates fibroblast-driven wound closure. Lin A, etal., Am J Pathol. 2010 Jan;176(1):108-21. doi: 10.2353/ajpath.2010.090256. Epub 2009 Dec 3.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Oral fibroblast expression of wound-inducible transcript 3.0 (wit3.0) accelerates the collagen gel contraction in vitro. Sukotjo C, etal., J Biol Chem. 2003 Dec 19;278(51):51527-34. Epub 2003 Oct 3.
7. Molecular cloning of wound inducible transcript (wit 3.0) differentially expressed in edentulous oral mucosa undergoing tooth extraction wound-healing. Sukotjo C, etal., J Dent Res 2002 Apr;81(4):229-35.
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Fgfr1op2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24179,491,602 - 179,512,630 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4179,491,599 - 179,512,630 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4185,777,106 - 185,798,069 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04181,561,631 - 181,582,590 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04180,182,049 - 180,203,008 (+)NCBIRnor_WKY
Rnor_6.04180,887,182 - 180,908,206 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4180,887,182 - 180,908,198 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04245,046,889 - 245,067,913 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44184,153,022 - 184,173,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14184,398,145 - 184,419,085 (+)NCBI
Celera4167,988,215 - 168,009,154 (+)NCBICelera
Cytogenetic Map4q44NCBI
FGFR1OP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381226,938,470 - 26,966,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1226,938,470 - 26,966,650 (+)EnsemblGRCh38hg38GRCh38
GRCh371227,091,403 - 27,119,581 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361226,982,583 - 27,010,129 (+)NCBINCBI36Build 36hg18NCBI36
Build 341226,982,582 - 27,010,129NCBI
Celera1232,237,461 - 32,265,742 (+)NCBICelera
Cytogenetic Map12p11.23NCBI
HuRef1226,861,362 - 26,889,645 (+)NCBIHuRef
CHM1_11227,056,349 - 27,084,628 (+)NCBICHM1_1
T2T-CHM13v2.01226,810,479 - 26,838,658 (+)NCBIT2T-CHM13v2.0
Fgfr1op2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396146,479,401 - 146,500,696 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6146,478,701 - 146,500,696 (+)EnsemblGRCm39 Ensembl
GRCm386146,577,903 - 146,599,198 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6146,577,203 - 146,599,198 (+)EnsemblGRCm38mm10GRCm38
MGSCv376146,526,433 - 146,547,720 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366146,535,105 - 146,556,360 (+)NCBIMGSCv36mm8
Celera6149,630,355 - 149,651,644 (+)NCBICelera
Cytogenetic Map6G3NCBI
Fgfr1op2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541321,814,278 - 21,844,232 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541321,814,133 - 21,843,105 (+)NCBIChiLan1.0ChiLan1.0
FGFR1OP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11261,960,483 - 61,986,826 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1261,960,483 - 61,986,826 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01259,345,834 - 59,372,895 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
FGFR1OP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12720,672,166 - 20,704,530 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2720,674,552 - 20,704,498 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2725,702,442 - 25,713,885 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02720,866,935 - 20,899,331 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2720,867,467 - 20,899,261 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12720,680,184 - 20,691,626 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02720,702,482 - 20,713,929 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02725,865,306 - 25,876,753 (+)NCBIUU_Cfam_GSD_1.0
Fgfr1op2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494582,598,532 - 82,613,814 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936548521,418 - 548,290 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGFR1OP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl546,794,110 - 46,824,153 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1546,794,118 - 46,824,062 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2550,345,625 - 50,375,535 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGFR1OP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11126,686,891 - 26,715,379 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1126,686,962 - 26,713,485 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660698,356,089 - 8,384,571 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgfr1op2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475212,226,729 - 12,257,357 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
BE107623  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24179,510,883 - 179,511,041 (+)MAPPERmRatBN7.2
Rnor_6.04180,906,460 - 180,906,617NCBIRnor6.0
Rnor_5.04245,066,167 - 245,066,324UniSTSRnor5.0
RGSC_v3.44184,172,300 - 184,172,457UniSTSRGSC3.4
Celera4168,007,493 - 168,007,650UniSTS
RH 3.4 Map41068.2UniSTS
Cytogenetic Map4q44UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:822
Count of miRNA genes:238
Interacting mature miRNAs:307
Transcripts:ENSRNOT00000002476, ENSRNOT00000042270
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 41 11 8
Low 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002476   ⟹   ENSRNOP00000002476
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4179,491,643 - 179,512,630 (+)Ensembl
Rnor_6.0 Ensembl4180,887,285 - 180,908,198 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000042270   ⟹   ENSRNOP00000039568
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4179,491,599 - 179,512,626 (+)Ensembl
Rnor_6.0 Ensembl4180,887,182 - 180,908,121 (+)Ensembl
RefSeq Acc Id: NM_201421   ⟹   NP_958824
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24179,491,604 - 179,512,545 (+)NCBI
Rnor_6.04180,887,182 - 180,908,121 (+)NCBI
Rnor_5.04245,046,889 - 245,067,913 (+)NCBI
RGSC_v3.44184,153,022 - 184,173,961 (+)RGD
Celera4167,988,215 - 168,009,154 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237688   ⟹   XP_006237750
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24179,491,602 - 179,512,630 (+)NCBI
Rnor_6.04180,887,193 - 180,908,206 (+)NCBI
Rnor_5.04245,046,889 - 245,067,913 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763402   ⟹   XP_008761624
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24179,491,603 - 179,508,803 (+)NCBI
Rnor_6.04180,887,203 - 180,904,352 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_958824   ⟸   NM_201421
- UniProtKB: Q6TA26 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006237750   ⟸   XM_006237688
- Peptide Label: isoform X1
- UniProtKB: Q6TA25 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008761624   ⟸   XM_008763402
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000002476   ⟸   ENSRNOT00000002476
RefSeq Acc Id: ENSRNOP00000039568   ⟸   ENSRNOT00000042270

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6TA25-F1-model_v2 AlphaFold Q6TA25 1-253 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693503
Promoter ID:EPDNEW_R4027
Type:initiation region
Name:Fgfr1op2_1
Description:FGFR1 oncogene partner 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04180,887,207 - 180,887,267EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303233 AgrOrtholog
BioCyc Gene G2FUF-42428 BioCyc
Ensembl Genes ENSRNOG00000001811 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002476 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000039568 ENTREZGENE
  ENSRNOP00000039568.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002476 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000042270 ENTREZGENE
  ENSRNOT00000042270.4 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7312267 IMAGE-MGC_LOAD
InterPro SIKE UniProtKB/Swiss-Prot
KEGG Report rno:362463 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105259 IMAGE-MGC_LOAD
NCBI Gene 362463 ENTREZGENE
PANTHER PTHR12186 UniProtKB/Swiss-Prot
Pfam SIKE UniProtKB/Swiss-Prot
PhenoGen Fgfr1op2 PhenoGen
UniProt A0A8L2QKW1_RAT UniProtKB/TrEMBL
  FGOP2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6TA26 ENTREZGENE
UniProt Secondary Q5PPH1 UniProtKB/Swiss-Prot
  Q6TA26 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Fgfr1op2  FGFR1 oncogene partner 2  Wit3.0  wound inducible transcript 3.0  Symbol and Name updated 1299863 APPROVED
2005-07-14 Wit3.0  wound inducible transcript 3.0      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in healing oral mucosal fibroblasts following tooth extraction 1303952
gene_transcript alternative transcripts include 215 amino acid peptide (wit 3.0 alpha) and 253 amino acid peptide (wit 3.0 beta) 1303952