Socs6 (suppressor of cytokine signaling 6) - Rat Genome Database

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Gene: Socs6 (suppressor of cytokine signaling 6) Rattus norvegicus
Analyze
Symbol: Socs6
Name: suppressor of cytokine signaling 6
RGD ID: 1304632
Description: Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to act upstream of or within negative regulation of T cell activation; proteasomal protein catabolic process; and regulation of growth. Predicted to be located in immunological synapse. Predicted to be part of phosphatidylinositol 3-kinase complex. Orthologous to human SOCS6 (suppressor of cytokine signaling 6); PARTICIPATES IN insulin signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC307200
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81884,386,587 - 84,413,927 (-)NCBIGRCr8
mRatBN7.21882,111,866 - 82,139,193 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1882,111,827 - 82,139,219 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1884,181,347 - 84,199,267 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01884,854,573 - 84,872,495 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01882,722,714 - 82,740,644 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01885,962,729 - 85,981,125 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1885,962,729 - 85,980,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01885,005,240 - 85,023,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41885,722,868 - 85,725,214 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11885,796,321 - 85,798,793 (-)NCBI
Celera1880,666,098 - 80,684,203 (-)NCBICelera
Cytogenetic Map18q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Attenuation of leptin and insulin signaling by SOCS proteins. Howard JK and Flier JS, Trends Endocrinol Metab. 2006 Nov;17(9):365-71. Epub 2006 Sep 28.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Inhibitors of cytokine signal transduction. Wormald S and Hilton DJ, J Biol Chem 2004 Jan 9;279(2):821-4. Epub 2003 Nov 7.
Additional References at PubMed
PMID:11342531   PMID:12052866   PMID:20007709   PMID:22125600   PMID:32587662   PMID:32668737  


Genomics

Comparative Map Data
Socs6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81884,386,587 - 84,413,927 (-)NCBIGRCr8
mRatBN7.21882,111,866 - 82,139,193 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1882,111,827 - 82,139,219 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1884,181,347 - 84,199,267 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01884,854,573 - 84,872,495 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01882,722,714 - 82,740,644 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01885,962,729 - 85,981,125 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1885,962,729 - 85,980,833 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01885,005,240 - 85,023,344 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41885,722,868 - 85,725,214 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11885,796,321 - 85,798,793 (-)NCBI
Celera1880,666,098 - 80,684,203 (-)NCBICelera
Cytogenetic Map18q13NCBI
SOCS6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381870,289,045 - 70,330,199 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1870,289,045 - 70,330,199 (+)EnsemblGRCh38hg38GRCh38
GRCh371867,956,281 - 67,997,435 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361866,107,117 - 66,148,414 (+)NCBINCBI36Build 36hg18NCBI36
Build 341866,107,242 - 66,145,328NCBI
Celera1864,803,527 - 64,844,775 (+)NCBICelera
Cytogenetic Map18q22.2NCBI
HuRef1864,675,129 - 64,716,511 (+)NCBIHuRef
CHM1_11867,951,383 - 67,992,682 (+)NCBICHM1_1
T2T-CHM13v2.01870,504,115 - 70,545,262 (+)NCBIT2T-CHM13v2.0
Socs6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391888,883,293 - 88,912,623 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1888,683,348 - 88,945,605 (-)EnsemblGRCm39 Ensembl
GRCm381888,865,169 - 88,894,364 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1888,665,224 - 88,927,481 (-)EnsemblGRCm38mm10GRCm38
MGSCv371889,037,272 - 89,063,599 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361889,002,071 - 89,028,400 (-)NCBIMGSCv36mm8
Celera1890,595,043 - 90,615,952 (-)NCBICelera
Cytogenetic Map18E4NCBI
cM Map1858.66NCBI
Socs6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540253,852,510 - 53,876,245 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540253,847,859 - 53,876,245 (+)NCBIChiLan1.0ChiLan1.0
SOCS6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21787,817,792 - 87,861,022 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11873,510,442 - 73,578,231 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01863,666,761 - 63,710,085 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11866,957,394 - 67,000,015 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1866,994,489 - 66,996,096 (+)Ensemblpanpan1.1panPan2
SOCS6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.118,078,500 - 8,117,651 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl18,082,389 - 8,083,996 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha19,053,320 - 9,127,874 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.017,914,975 - 7,954,235 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl17,914,977 - 7,954,284 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.117,900,976 - 7,975,745 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.017,889,975 - 7,929,220 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.018,099,778 - 8,139,047 (-)NCBIUU_Cfam_GSD_1.0
Socs6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494421,889,210 - 21,907,684 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936964174,165 - 179,813 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOCS6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1152,593,653 - 152,636,650 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11152,593,647 - 152,636,645 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21168,991,451 - 168,993,887 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SOCS6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1189,445,820 - 9,488,125 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl189,449,740 - 9,451,347 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606016,327,085 - 16,369,287 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Socs6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462480610,921,204 - 10,949,108 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Socs6
93 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:158
Count of miRNA genes:129
Interacting mature miRNAs:142
Transcripts:ENSRNOT00000058179
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578661Bss20Bone structure and strength QTL 203.7femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)181179151883218561Rat
1578667Bss21Bone structure and strength QTL 213.5femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)181179151883218561Rat
1600373Mamtr6Mammary tumor resistance QTL 6mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)181927890183218561Rat
1331741Bp232Blood pressure QTL 2323.59112arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)182137289383213037Rat
2303120Mamtr8Mammary tumor resistance QTL 80.001mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)183135940883218561Rat
61367Iddm4Insulin dependent diabetes mellitus QTL 42.330.0074blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)183819245583192455Rat
1598826Anxrr20Anxiety related response QTL 203.04body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)184143297183828827Rat
6893683Bw110Body weight QTL 1102.70.002body mass (VT:0001259)body weight (CMO:0000012)184334502283828827Rat
8694366Abfw8Abdominal fat weight QTL 86.380.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)184664067583828827Rat
8694432Bw165Body weight QTL 1653.810.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)184664067583828827Rat
9589041Epfw12Epididymal fat weight QTL 1217.080.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)184664067583828827Rat
2303571Bw92Body weight QTL 923body mass (VT:0001259)body weight (CMO:0000012)184852004483828827Rat
2303584Gluco55Glucose level QTL 552blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)184852004483828827Rat
738008Hcar14Hepatocarcinoma resistance QTL 144.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion number (CMO:0001462)185146473383218561Rat
1298072Cia26Collagen induced arthritis QTL 263.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)185470976983828827Rat
724542Kidm2Kidney mass QTL 22.6kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)185917211583828827Rat
6903353Bp353Blood pressure QTL 3532.8arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)185979647883828827Rat
6903356Bp354Blood pressure QTL 3544.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)185979647883828827Rat

Markers in Region
D18Got78  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21882,119,363 - 82,119,597 (+)MAPPERmRatBN7.2
Rnor_6.01885,967,120 - 85,967,353NCBIRnor6.0
Rnor_5.01885,009,631 - 85,009,864UniSTSRnor5.0
RGSC_v3.41885,726,919 - 85,727,149RGDRGSC3.4
RGSC_v3.41885,726,917 - 85,727,150UniSTSRGSC3.4
RGSC_v3.11885,800,369 - 85,800,599RGD
Celera1880,670,490 - 80,670,723UniSTS
RH 3.4 Map18844.9UniSTS
RH 3.4 Map18844.9RGD
RH 2.0 Map180.0RGD
Cytogenetic Map18q13UniSTS
STS-N33129  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21882,115,269 - 82,115,401 (+)MAPPERmRatBN7.2
Rnor_6.01885,963,026 - 85,963,157NCBIRnor6.0
Rnor_5.01885,005,537 - 85,005,668UniSTSRnor5.0
RGSC_v3.41885,722,823 - 85,722,954UniSTSRGSC3.4
Celera1880,666,395 - 80,666,526UniSTS
Cytogenetic Map18q13UniSTS
RH142286  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21882,115,589 - 82,115,760 (+)MAPPERmRatBN7.2
Rnor_6.01885,963,346 - 85,963,516NCBIRnor6.0
Rnor_5.01885,005,857 - 85,006,027UniSTSRnor5.0
RGSC_v3.41885,723,143 - 85,723,313UniSTSRGSC3.4
Celera1880,666,715 - 80,666,885UniSTS
RH 3.4 Map18849.0UniSTS
Cytogenetic Map18q13UniSTS
RH138814  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21882,115,812 - 82,116,017 (+)MAPPERmRatBN7.2
Rnor_6.01885,963,569 - 85,963,773NCBIRnor6.0
Rnor_5.01885,006,080 - 85,006,284UniSTSRnor5.0
RGSC_v3.41885,723,366 - 85,723,570UniSTSRGSC3.4
Celera1880,666,938 - 80,667,142UniSTS
RH 3.4 Map18845.8UniSTS
Cytogenetic Map18q13UniSTS
Socs6  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21882,116,643 - 82,116,954 (+)MAPPERmRatBN7.2
Rnor_6.01885,964,400 - 85,964,710NCBIRnor6.0
Rnor_5.01885,006,911 - 85,007,221UniSTSRnor5.0
RGSC_v3.41885,724,197 - 85,724,507UniSTSRGSC3.4
Celera1880,667,769 - 80,668,080UniSTS
Cytogenetic Map18q13UniSTS
ksks24  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21882,116,053 - 82,116,401 (+)MAPPERmRatBN7.2
Rnor_6.01885,963,810 - 85,964,157NCBIRnor6.0
Rnor_5.01885,006,321 - 85,006,668UniSTSRnor5.0
RGSC_v3.41885,723,607 - 85,723,954UniSTSRGSC3.4
Celera1880,667,179 - 80,667,526UniSTS
Cytogenetic Map18q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 22 8 19 8 8 10 68 27 34 11 8
Low 35 33 33 1 6 8 7
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000058179   ⟹   ENSRNOP00000054982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1882,114,316 - 82,128,365 (-)Ensembl
Rnor_6.0 Ensembl1885,962,729 - 85,980,833 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095498   ⟹   ENSRNOP00000091475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1882,111,827 - 82,139,219 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119275   ⟹   ENSRNOP00000089791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1882,111,827 - 82,139,219 (-)Ensembl
RefSeq Acc Id: NM_001271149   ⟹   NP_001258078
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81884,389,691 - 84,407,799 (-)NCBI
mRatBN7.21882,114,971 - 82,133,081 (-)NCBI
Rnor_6.01885,962,729 - 85,980,833 (-)NCBI
Rnor_5.01885,005,240 - 85,023,344 (-)NCBI
Celera1880,666,098 - 80,684,203 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039096760   ⟹   XP_038952688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81884,386,587 - 84,413,927 (-)NCBI
mRatBN7.21882,111,866 - 82,139,193 (-)NCBI
RefSeq Acc Id: XM_039096761   ⟹   XP_038952689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81884,386,587 - 84,413,913 (-)NCBI
mRatBN7.21882,111,866 - 82,139,193 (-)NCBI
RefSeq Acc Id: XM_039096762   ⟹   XP_038952690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81884,386,587 - 84,413,912 (-)NCBI
mRatBN7.21882,111,866 - 82,139,193 (-)NCBI
RefSeq Acc Id: XM_039096763   ⟹   XP_038952691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81884,386,587 - 84,413,912 (-)NCBI
mRatBN7.21882,111,866 - 82,139,193 (-)NCBI
RefSeq Acc Id: XM_039096764   ⟹   XP_038952692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81884,386,587 - 84,413,912 (-)NCBI
mRatBN7.21882,111,866 - 82,139,193 (-)NCBI
RefSeq Acc Id: NP_001258078   ⟸   NM_001271149
- UniProtKB: D3ZS84 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000054982   ⟸   ENSRNOT00000058179
RefSeq Acc Id: XP_038952692   ⟸   XM_039096764
- Peptide Label: isoform X1
- UniProtKB: D3ZS84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952688   ⟸   XM_039096760
- Peptide Label: isoform X1
- UniProtKB: D3ZS84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952691   ⟸   XM_039096763
- Peptide Label: isoform X1
- UniProtKB: D3ZS84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952689   ⟸   XM_039096761
- Peptide Label: isoform X1
- UniProtKB: D3ZS84 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952690   ⟸   XM_039096762
- Peptide Label: isoform X1
- UniProtKB: D3ZS84 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000091475   ⟸   ENSRNOT00000095498
RefSeq Acc Id: ENSRNOP00000089791   ⟸   ENSRNOT00000119275
Protein Domains
SH2   SOCS box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZS84-F1-model_v2 AlphaFold D3ZS84 1-547 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304632 AgrOrtholog
BioCyc Gene G2FUF-6696 BioCyc
Ensembl Genes ENSRNOG00000038212 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000058179 ENTREZGENE
  ENSRNOT00000058179.5 UniProtKB/TrEMBL
  ENSRNOT00000095498.1 UniProtKB/TrEMBL
  ENSRNOT00000119275.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/TrEMBL
  SOCS box UniProtKB/TrEMBL
InterPro SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SOCS6_SH2 UniProtKB/TrEMBL
  SOCS6_SOCS UniProtKB/TrEMBL
  SOCS_box_dom_like UniProtKB/TrEMBL
  SOCS_C UniProtKB/TrEMBL
KEGG Report rno:307200 UniProtKB/TrEMBL
NCBI Gene 307200 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT UniProtKB/TrEMBL
  SUPPRESSOR OF CYTOKINE SIGNALING 6 UniProtKB/TrEMBL
Pfam SH2 UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
PhenoGen Socs6 PhenoGen
PROSITE SH2 UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
RatGTEx ENSRNOG00000038212 RatGTEx
SMART SH2 UniProtKB/TrEMBL
  SOCS UniProtKB/TrEMBL
  SOCS_box UniProtKB/TrEMBL
Superfamily-SCOP SSF158235 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt D3ZS84 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Socs6  suppressor of cytokine signaling 6   Socs6_predicted  suppressor of cytokine signaling 6 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Socs6_predicted  suppressor of cytokine signaling 6 (predicted)      Symbol and Name status set to approved 70820 APPROVED