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Gene: Chrnb3 (cholinergic receptor nicotinic beta 3 subunit) Rattus norvegicus
Symbol: Chrnb3
Name: cholinergic receptor nicotinic beta 3 subunit
RGD ID: 621544
Description: Exhibits acetylcholine binding activity. Predicted to contribute to acetylcholine receptor activity. Predicted to be involved in several processes, including cholinergic synaptic transmission; regulation of synaptic vesicle exocytosis; and response to nicotine. Localizes to acetylcholine-gated channel complex and neuron projection. Orthologous to human CHRNB3 (cholinergic receptor nicotinic beta 3 subunit); PARTICIPATES IN acetylcholine signaling pathway via nicotinic acetylcholine receptor; INTERACTS WITH (S)-nicotine; acrylamide; bisphenol A.
Type: protein-coding
Also known as: cholinergic receptor, nicotinic beta 3; cholinergic receptor, nicotinic, beta 3; cholinergic receptor, nicotinic, beta 3 (neuronal); cholinergic receptor, nicotinic, beta polypeptide 3; neuronal acetylcholine receptor subunit beta-3
Homo sapiens (human) : CHRNB3 (cholinergic receptor nicotinic beta 3 subunit)  HGNC  Alliance
Mus musculus (house mouse) : Chrnb3 (cholinergic receptor, nicotinic, beta polypeptide 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chrnb3 (cholinergic receptor nicotinic beta 3 subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : CHRNB3 (cholinergic receptor nicotinic beta 3 subunit)
Canis lupus familiaris (dog) : CHRNB3 (cholinergic receptor nicotinic beta 3 subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chrnb3 (cholinergic receptor nicotinic beta 3 subunit)
Sus scrofa (pig) : CHRNB3 (cholinergic receptor nicotinic beta 3 subunit)
Chlorocebus sabaeus (African green monkey) : CHRNB3 (cholinergic receptor nicotinic beta 3 subunit)
Heterocephalus glaber (naked mole-rat) : Chrnb3 (cholinergic receptor nicotinic beta 3 subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01668,876,442 - 68,913,628 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1668,875,709 - 68,913,628 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01668,502,911 - 68,539,031 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41669,028,625 - 69,069,274 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11669,028,830 - 69,069,480 (-)NCBI
Celera1662,637,536 - 62,674,782 (-)NCBICelera
Cytogenetic Map16q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Chrnb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621544
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.