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Gene: Macrod2 (mono-ADP ribosylhydrolase 2) Rattus norvegicus
Symbol: Macrod2
Name: mono-ADP ribosylhydrolase 2
Description: Predicted to have ADP-ribosylglutamate hydrolase activity and deacetylase activity. Predicted to be involved in several processes, including peptidyl-glutamate ADP-deribosylation; purine nucleoside metabolic process; and response to bacterium. Predicted to localize to the nucleolus and nucleoplasm. Orthologous to human MACROD2 (mono-ADP ribosylhydrolase 2); PARTICIPATES IN ADP-ribosylation pathway, mono and poly-ribosylation; INTERACTS WITH bisphenol A; indole-3-methanol; manganese(II) chloride.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC685695; MACRO domain containing 2; O-acetyl-ADP-ribose deacetylase MACROD2; similar to LRP16 protein; similar to SON protein
Homo sapiens (human) : MACROD2 (mono-ADP ribosylhydrolase 2)  HGNC  Alliance
Mus musculus (house mouse) : Macrod2 (mono-ADP ribosylhydrolase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Macrod2 (mono-ADP ribosylhydrolase 2)
Canis lupus familiaris (dog) : MACROD2 (mono-ADP ribosylhydrolase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Macrod2 (mono-ADP ribosylhydrolase 2)
Sus scrofa (pig) : MACROD2 (mono-ADP ribosylhydrolase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03135,729,839 - 136,422,082 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03140,866,319 - 142,867,324 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43128,570,984 - 130,673,729 (+)NCBIRGSC3.4rn4RGSC3.4
Celera3127,663,937 - 128,671,039 (+)NCBICelera
Cytogenetic Map3q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Macrod2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1591318
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.