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Gene: Bco1 (beta-carotene oxygenase 1) Rattus norvegicus
Symbol: Bco1
Name: beta-carotene oxygenase 1
RGD ID: 70981
Description: Exhibits beta-carotene 15,15'-monooxygenase activity. Involved in retinoid metabolic process. Orthologous to human BCO1 (beta-carotene oxygenase 1); PARTICIPATES IN retinol metabolic pathway; vitamin A deficiency pathway; INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; 9-cis-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Bcdo; Bcmo1; beta,beta-carotene 15,15'-dioxygenase; beta,beta-carotene 15,15'-monooxygenase; beta-carotene 15 15'-dioxygenase; beta-carotene 15 15-dioxygenase; beta-carotene 15, 15'-dioxygenase; beta-carotene 15, 15-dioxygenase; beta-carotene 15,15'-monooxygenase; beta-carotene 15,15'-monooxygenase 1; beta-carotene dioxygenase 1
Homo sapiens (human) : BCO1 (beta-carotene oxygenase 1)  HGNC  Alliance
Mus musculus (house mouse) : Bco1 (beta-carotene oxygenase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bco1 (beta-carotene oxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : BCO1 (beta-carotene oxygenase 1)
Canis lupus familiaris (dog) : BCO1 (beta-carotene oxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bco1 (beta-carotene oxygenase 1)
Sus scrofa (pig) : BCO1 (beta-carotene oxygenase 1)
Chlorocebus sabaeus (African green monkey) : BCO1 (beta-carotene oxygenase 1)
Heterocephalus glaber (naked mole-rat) : Bco1 (beta-carotene oxygenase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01949,637,059 - 49,673,577 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1949,637,016 - 49,673,808 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01960,424,580 - 60,460,636 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41947,202,955 - 47,239,225 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11947,207,835 - 47,244,106 (+)NCBI
Celera1944,421,345 - 44,457,802 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Bco1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70981
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.