Pax3 (paired box 3) - Rat Genome Database

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Gene: Pax3 (paired box 3) Rattus norvegicus
Analyze
Symbol: Pax3
Name: paired box 3
RGD ID: 620431
Description: Enables HMG box domain binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including nervous system development; regulation of somitogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Human ortholog(s) of this gene implicated in Waardenburg syndrome; Waardenburg syndrome type 1; Waardenburg syndrome type 3; alveolar rhabdomyosarcoma; and craniofacial-deafness-hand syndrome. Orthologous to human PAX3 (paired box 3); INTERACTS WITH (S)-nicotine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homeodomain protein PAX3; paired box gene 3; paired box protein Pax-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2979,567,455 - 79,664,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl979,568,634 - 79,664,042 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx987,998,443 - 88,093,830 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0993,111,318 - 93,206,669 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0991,509,872 - 91,605,274 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0984,004,004 - 84,101,226 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,005,183 - 84,101,172 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0983,765,158 - 83,871,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,477,813 - 77,576,632 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1977,692,768 - 77,692,881 (-)NCBI
Celera977,080,699 - 77,176,237 (-)NCBICelera
Cytogenetic Map9q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R,R,R)-alpha-tocopherol  (ISO)
(S)-nicotine  (EXP)
1,2-dichloroethane  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-di-tert-butylphenol  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-bromo-2'-deoxyuridine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
abacavir  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (ISO)
all-trans-retinol  (EXP)
amiodarone  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
ANTIMYCIN  (ISO)
arsenite(3-)  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
cadmium atom  (ISO)
cadmium sulfate  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
CHIR 99021  (ISO)
choline  (ISO)
copper(II) sulfate  (ISO)
cycloheximide  (ISO)
D-glucose  (EXP,ISO)
dabigatran  (ISO)
dexamethasone  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
entinostat  (ISO)
ethylene glycol  (ISO)
fluoxetine  (ISO)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
glucose  (EXP,ISO)
Glutathione ethyl ester  (ISO)
glycolic acid  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
lithium chloride  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
methylparaben  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-ethyl-N-nitrosourea  (ISO)
nicotine  (EXP)
nilotinib  (ISO)
nitrofen  (EXP)
panobinostat  (ISO)
permethrin  (EXP)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
propanal  (ISO)
propiconazole  (EXP)
Ptaquiloside  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
stilbenoid  (ISO)
streptomycin  (ISO)
sunitinib  (ISO)
thalidomide  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Pax3 mRNA is decreased in the hearts of rats with experimental diaphragmatic hernia. Gonzalez-Reyes S, etal., Pediatr Surg Int. 2005 Mar;21(3):203-7. Epub 2004 Dec 23.
3. Sox10, a novel transcriptional modulator in glial cells. Kuhlbrodt K, etal., J Neurosci 1998 Jan 1;18(1):237-50.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma. Misuraca KL, etal., Acta Neuropathol Commun. 2014 Oct 21;2:134. doi: 10.1186/s40478-014-0134-6.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. The mutational spectrum in Waardenburg syndrome. Tassabehji M, etal., Hum Mol Genet. 1995 Nov;4(11):2131-7.
12. Gene expression signatures identify rhabdomyosarcoma subtypes and detect a novel t(2;2)(q35;p23) translocation fusing PAX3 to NCOA1. Wachtel M, etal., Cancer Res. 2004 Aug 15;64(16):5539-45.
13. The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. Wissmuller S, etal., Nucleic Acids Res. 2006 Mar 31;34(6):1735-44. Print 2006.
14. Homozygous and heterozygous inheritance of PAX3 mutations causes different types of Waardenburg syndrome. Wollnik B, etal., Am J Med Genet A. 2003 Sep 15;122(1):42-5.
Additional References at PubMed
PMID:9858722   PMID:10231856   PMID:10419687   PMID:10946068   PMID:11863357   PMID:15132998   PMID:15322542   PMID:15384171   PMID:15729346   PMID:16300735   PMID:16720875   PMID:17974128  
PMID:18508329   PMID:19101644   PMID:21177767   PMID:21371476   PMID:22532290   PMID:22703771   PMID:24443808   PMID:28223217   PMID:29134414  


Genomics

Comparative Map Data
Pax3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2979,567,455 - 79,664,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl979,568,634 - 79,664,042 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx987,998,443 - 88,093,830 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0993,111,318 - 93,206,669 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0991,509,872 - 91,605,274 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0984,004,004 - 84,101,226 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,005,183 - 84,101,172 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0983,765,158 - 83,871,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,477,813 - 77,576,632 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1977,692,768 - 77,692,881 (-)NCBI
Celera977,080,699 - 77,176,237 (-)NCBICelera
Cytogenetic Map9q33NCBI
PAX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382222,199,887 - 222,298,998 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2222,199,887 - 222,298,998 (-)EnsemblGRCh38hg38GRCh38
GRCh372223,064,606 - 223,163,717 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,772,851 - 222,871,944 (-)NCBINCBI36Build 36hg18NCBI36
Build 342222,891,555 - 222,989,205NCBI
Celera2216,832,726 - 216,931,738 (-)NCBICelera
Cytogenetic Map2q36.1NCBI
HuRef2214,918,697 - 215,017,780 (-)NCBIHuRef
CHM1_12223,071,095 - 223,170,215 (-)NCBICHM1_1
T2T-CHM13v2.02222,684,993 - 222,784,124 (-)NCBIT2T-CHM13v2.0
Pax3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,077,904 - 78,173,773 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,077,904 - 78,173,771 (-)EnsemblGRCm39 Ensembl
GRCm38178,101,267 - 78,197,136 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,101,267 - 78,197,134 (-)EnsemblGRCm38mm10GRCm38
MGSCv37178,097,842 - 78,193,711 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36177,985,839 - 78,080,283 (-)NCBIMGSCv36mm8
Celera178,585,057 - 78,620,745 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map139.79NCBI
Pax3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545311,463,379 - 11,558,006 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545311,463,407 - 11,558,001 (+)NCBIChiLan1.0ChiLan1.0
PAX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12B124,829,836 - 124,951,447 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B109,441,938 - 109,541,449 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B228,022,453 - 228,121,850 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B228,022,453 - 228,121,874 (-)Ensemblpanpan1.1panPan2
PAX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13728,346,476 - 28,443,648 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3728,346,563 - 28,444,561 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3729,183,832 - 29,282,546 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03728,371,451 - 28,469,641 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3728,371,535 - 28,469,658 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13728,283,899 - 28,382,350 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03728,214,748 - 28,313,220 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03728,233,000 - 28,331,742 (-)NCBIUU_Cfam_GSD_1.0
Dog Cytomap37q16-q17NCBI
Pax3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303177,872,678 - 177,964,983 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365694,216,900 - 4,307,815 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365694,215,513 - 4,307,815 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15124,094,295 - 124,193,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115124,093,803 - 124,193,041 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PAX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110108,125,198 - 108,225,217 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10108,125,747 - 108,224,478 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604091,149,850 - 91,250,433 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pax3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248232,871,162 - 2,961,944 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248232,870,762 - 2,963,134 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pax3
379 total Variants
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir1rno-miR-1-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21730146
Mir206rno-miR-206-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI21730146

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:60
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000018652
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)96207227596470995Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)96207227596470995Rat
61385Edpm9Estrogen-dependent pituitary mass QTL 93.430.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)963869687108869687Rat
731171Glom6Glomerulus QTL 62.80.0003kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)964573531109573531Rat
1354626Bvd1Brain ventricular dilatation QTL 13.730.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)975712843111552878Rat
4889852Pur26Proteinuria QTL 26150.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)977813894101597663Rat
7794784Mcs31Mammary carcinoma susceptibility QTL 312.98mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)977813894111552878Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)97927151191616855Rat
2303178Bp334Blood pressure QTL 3343.70.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)97927151191616855Rat
724547Cm21Cardiac mass QTL 212.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)979271511102910209Rat

Markers in Region
X59358  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,569,298 - 79,569,447 (+)MAPPERmRatBN7.2
Rnor_6.0984,005,848 - 84,005,996NCBIRnor6.0
Rnor_5.0983,767,002 - 83,767,150UniSTSRnor5.0
RGSC_v3.4977,478,478 - 77,478,626UniSTSRGSC3.4
Celera977,081,364 - 77,081,512UniSTS
Cytogenetic Map9q33UniSTS
RH142754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2979,647,711 - 79,647,865 (+)MAPPERmRatBN7.2
Rnor_6.0984,084,433 - 84,084,586NCBIRnor6.0
Rnor_5.0983,845,657 - 83,845,810UniSTSRnor5.0
RGSC_v3.4977,559,803 - 77,559,956UniSTSRGSC3.4
Celera977,160,102 - 77,160,255UniSTS
RH 3.4 Map9734.1UniSTS
Cytogenetic Map9q33UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 21 2
Low 1 3 25 9 1
Below cutoff 2 15 5 7 5 7 8 18 2 17 7 7

Sequence


RefSeq Acc Id: ENSRNOT00000018652   ⟹   ENSRNOP00000018652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl979,568,634 - 79,664,042 (-)Ensembl
Rnor_6.0 Ensembl984,005,183 - 84,101,172 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102177   ⟹   ENSRNOP00000095553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl979,569,121 - 79,664,042 (-)Ensembl
RefSeq Acc Id: NM_053710   ⟹   NP_446162
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2979,568,634 - 79,664,042 (-)NCBI
Rnor_6.0984,005,183 - 84,101,172 (-)NCBI
Rnor_5.0983,765,158 - 83,871,411 (-)NCBI
RGSC_v3.4977,477,813 - 77,576,632 (-)RGD
Celera977,080,699 - 77,176,237 (-)RGD
Sequence:
RefSeq Acc Id: XM_006245131   ⟹   XP_006245193
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2979,567,455 - 79,664,002 (-)NCBI
Rnor_6.0984,004,004 - 84,101,226 (-)NCBI
Rnor_5.0983,765,158 - 83,871,411 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_446162 (Get FASTA)   NCBI Sequence Viewer  
  XP_006245193 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK70501 (Get FASTA)   NCBI Sequence Viewer  
  AAO17711 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018652
  ENSRNOP00000018652.5
  ENSRNOP00000095553.1
RefSeq Acc Id: NP_446162   ⟸   NM_053710
- UniProtKB: F1LMV3 (UniProtKB/TrEMBL),   A0A8I6ATQ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245193   ⟸   XM_006245131
- Peptide Label: isoform X1
- UniProtKB: A0A8I6ATQ4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000018652   ⟸   ENSRNOT00000018652
RefSeq Acc Id: ENSRNOP00000095553   ⟸   ENSRNOT00000102177
Protein Domains
Homeobox   Paired

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LMV3-F1-model_v2 AlphaFold F1LMV3 1-484 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620431 AgrOrtholog
BioCyc Gene G2FUF-27029 BioCyc
Ensembl Genes ENSRNOG00000013670 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018652 ENTREZGENE
  ENSRNOT00000018652.6 UniProtKB/TrEMBL
  ENSRNOT00000102177.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox_CS UniProtKB/TrEMBL
  Homeodomain UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
  PAIRED_DNA_bd_dom UniProtKB/TrEMBL
  Paired_dom UniProtKB/TrEMBL
  Pax7 UniProtKB/TrEMBL
  PAX_fam UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report rno:114502 UniProtKB/TrEMBL
NCBI Gene 114502 ENTREZGENE
PANTHER DORSAL ROOT GANGLIA HOMEOBOX, ISOFORM E-RELATED UniProtKB/TrEMBL
  HOMEOBOX PROTEIN ARISTALESS UniProtKB/TrEMBL
  PAIRED BOX PROTEIN PAX-3 UniProtKB/TrEMBL
  PTHR45636 UniProtKB/TrEMBL
Pfam Homeobox UniProtKB/TrEMBL
  PAX UniProtKB/TrEMBL
  Pax7 UniProtKB/TrEMBL
PhenoGen Pax3 PhenoGen
PRINTS PAIREDBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  PAIRED_1 UniProtKB/TrEMBL
  PAIRED_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013670 RatGTEx
SMART HOX UniProtKB/TrEMBL
  PAX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt A0A8I6ATQ4 ENTREZGENE, UniProtKB/TrEMBL
  F1LMV3 ENTREZGENE, UniProtKB/TrEMBL
  Q91XM5_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-30 Pax3  paired box 3  Pax3  paired box gene 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Pax3  paired box gene 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Pax3  paired box gene 3      Symbol and Name status set to provisional 70820 PROVISIONAL