Pax3 (paired box 3) - Rat Genome Database

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Gene: Pax3 (paired box 3) Ictidomys tridecemlineatus
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Symbol: Pax3
Name: paired box 3
RGD ID: 12588756
Description: ENCODES a protein that exhibits chromatin binding (ortholog); HMG box domain binding (ortholog); transcription coregulator binding (ortholog); INVOLVED IN cell migration (ortholog); cell population proliferation (ortholog); developmental pigmentation (ortholog); ASSOCIATED WITH alveolar rhabdomyosarcoma (ortholog); brain stem glioma (ortholog); congenital diaphragmatic hernia (ortholog); FOUND IN nucleoplasm (inferred); nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: paired box 3, transcript variant X1; paired box 3, transcript variant X2; paired box 3, transcript variant X3; paired box 3, transcript variant X4; paired box 3, transcript variant X5; paired box 3, transcript variant X6; paired box protein Pax-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303177,872,678 - 177,964,983 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365694,216,900 - 4,307,815 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365694,215,513 - 4,307,815 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pax3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303177,872,678 - 177,964,983 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365694,216,900 - 4,307,815 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365694,215,513 - 4,307,815 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAX3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382222,199,887 - 222,298,998 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2222,199,887 - 222,298,998 (-)EnsemblGRCh38hg38GRCh38
GRCh372223,064,606 - 223,163,717 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,772,851 - 222,871,944 (-)NCBINCBI36Build 36hg18NCBI36
Build 342222,891,555 - 222,989,205NCBI
Celera2216,832,726 - 216,931,738 (-)NCBICelera
Cytogenetic Map2q36.1NCBI
HuRef2214,918,697 - 215,017,780 (-)NCBIHuRef
CHM1_12223,071,095 - 223,170,215 (-)NCBICHM1_1
T2T-CHM13v2.02222,684,993 - 222,784,124 (-)NCBIT2T-CHM13v2.0
Pax3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39178,077,904 - 78,173,773 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl178,077,904 - 78,173,771 (-)EnsemblGRCm39 Ensembl
GRCm38178,101,267 - 78,197,136 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl178,101,267 - 78,197,134 (-)EnsemblGRCm38mm10GRCm38
MGSCv37178,097,842 - 78,193,711 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36177,985,839 - 78,080,283 (-)NCBIMGSCv36mm8
Celera178,585,057 - 78,620,745 (-)NCBICelera
Cytogenetic Map1C4NCBI
cM Map139.79NCBI
Pax3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8987,015,960 - 87,112,531 (-)NCBIGRCr8
mRatBN7.2979,567,455 - 79,664,042 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl979,568,634 - 79,664,042 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx987,998,443 - 88,093,830 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0993,111,318 - 93,206,669 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0991,509,872 - 91,605,274 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0984,004,004 - 84,101,226 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,005,183 - 84,101,172 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0983,765,158 - 83,871,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4977,477,813 - 77,576,632 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1977,692,768 - 77,692,881 (-)NCBI
Celera977,080,699 - 77,176,237 (-)NCBICelera
Cytogenetic Map9q33NCBI
Pax3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545311,463,379 - 11,558,006 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545311,463,407 - 11,558,001 (+)NCBIChiLan1.0ChiLan1.0
PAX3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213124,814,872 - 124,914,320 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B124,829,836 - 124,951,447 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B109,441,938 - 109,541,449 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B228,022,453 - 228,121,850 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B228,022,453 - 228,121,874 (-)Ensemblpanpan1.1panPan2
PAX3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13728,346,476 - 28,443,648 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3728,346,563 - 28,444,561 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3729,183,832 - 29,282,546 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03728,371,451 - 28,469,641 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3728,371,535 - 28,469,658 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13728,283,899 - 28,382,350 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03728,214,748 - 28,313,220 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03728,233,000 - 28,331,742 (-)NCBIUU_Cfam_GSD_1.0
Dog Cytomap37q16-q17NCBI
PAX3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15124,094,295 - 124,193,011 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115124,093,803 - 124,193,041 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PAX3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.110108,125,198 - 108,225,217 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl10108,125,747 - 108,224,478 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604091,149,850 - 91,250,433 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pax3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248232,871,162 - 2,961,944 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248232,870,762 - 2,963,134 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSSTOT00000008646   ⟹   ENSSTOP00000007751
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049365694,216,900 - 4,307,815 (-)Ensembl
RefSeq Acc Id: XM_005330531   ⟹   XP_005330588
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303177,872,678 - 177,964,983 (-)NCBI
SpeTri2.0NW_0049365694,215,513 - 4,307,815 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005330532   ⟹   XP_005330589
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303177,872,678 - 177,964,983 (-)NCBI
SpeTri2.0NW_0049365694,215,513 - 4,307,815 (-)NCBI
Sequence:
RefSeq Acc Id: XM_021730009   ⟹   XP_021585684
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405303177,872,678 - 177,964,983 (-)NCBI
SpeTri2.0NW_0049365694,216,572 - 4,307,815 (-)NCBI
Sequence:
RefSeq Acc Id: XP_005330589   ⟸   XM_005330532
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_005330588   ⟸   XM_005330531
- Peptide Label: isoform X1
- UniProtKB: I3MC09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_021585684   ⟸   XM_021730009
- Peptide Label: isoform X3
- Sequence:
Ensembl Acc Id: ENSSTOP00000007751   ⟸   ENSSTOT00000008646
Protein Domains
Homeobox   Paired


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000008650 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000008646.3 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  PAIRED_DNA-bd_dom UniProtKB/TrEMBL
  Paired_dom UniProtKB/TrEMBL
  Pax7_C UniProtKB/TrEMBL
  PAX_fam UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Pax3 ENTREZGENE
PANTHER PAIRED BOX PROTEIN PAX-3 UniProtKB/TrEMBL
  PTHR45636 UniProtKB/TrEMBL
Pfam Homeodomain UniProtKB/TrEMBL
  PAX UniProtKB/TrEMBL
  Pax7 UniProtKB/TrEMBL
PRINTS PAIREDBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
  PAIRED_1 UniProtKB/TrEMBL
  PAIRED_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  PAX UniProtKB/TrEMBL
Superfamily-SCOP SSF46689 UniProtKB/TrEMBL
UniProt I3MC09 ENTREZGENE, UniProtKB/TrEMBL