Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tusc3 (tumor suppressor candidate 3) Rattus norvegicus
Analyze
Symbol: Tusc3
Name: tumor suppressor candidate 3
Description: Predicted to contribute to dolichyl-diphosphooligosaccharide-protein glycotransferase activity. Predicted to be involved in cognition; magnesium ion transport; and protein N-linked glycosylation via asparagine. Predicted to localize to the mitochondrion and oligosaccharyltransferase complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human TUSC3 (tumor suppressor candidate 3); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC94243; similar to N33 protein
Orthologs:
Homo sapiens (human) : TUSC3 (tumor suppressor candidate 3)  HGNC  Alliance
Mus musculus (house mouse) : Tusc3 (tumor suppressor candidate 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tusc3 (tumor suppressor candidate 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TUSC3 (tumor suppressor candidate 3)
Canis lupus familiaris (dog) : TUSC3 (tumor suppressor candidate 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tusc3 (tumor suppressor candidate 3)
Sus scrofa (pig) : TUSC3 (tumor suppressor candidate 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01656,248,125 - 56,396,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01655,949,774 - 56,097,482 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41656,760,904 - 56,929,685 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11656,760,980 - 56,929,760 (-)NCBI
Celera1651,081,032 - 51,229,180 (-)NCBICelera
Cytogenetic Map16q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tusc3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1303318
Created: 2004-12-03
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.