Hira (histone cell cycle regulator) - Rat Genome Database

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Gene: Hira (histone cell cycle regulator) Rattus norvegicus
Analyze
Symbol: Hira
Name: histone cell cycle regulator
RGD ID: 1584950
Description: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity and histone binding activity. Predicted to contribute to nucleosome binding activity. Predicted to be involved in nucleosome assembly. Predicted to act upstream of or within gastrulation; muscle cell differentiation; and osteoblast differentiation. Predicted to be located in chromatin and nucleoplasm. Predicted to be part of HIR complex. Orthologous to human HIRA (histone cell cycle regulator); PARTICIPATES IN histone modification pathway; INTERACTS WITH 3-chloropropane-1,2-diol; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: HIR histone cell cycle regulation defective homolog A; HIR histone cell cycle regulation defective homolog A (S. cerevisiae); histone cell cycle regulation defective homolog A; LOC100911837; LOC363849; protein HIRA-like; similar to histone cell cycle regulation defective homolog A isoform 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21182,024,469 - 82,133,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,024,469 - 82,133,529 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,753,636 - 90,862,674 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01183,414,851 - 83,523,894 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01182,468,120 - 82,577,162 (-)NCBIRnor_WKY
Rnor_6.01186,168,196 - 86,276,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,168,196 - 86,276,430 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,270,162 - 89,378,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,805,603 - 80,913,841 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone chaperones in nucleosome assembly and human disease. Burgess RJ and Zhang Z, Nat Struct Mol Biol. 2013 Jan;20(1):14-22. doi: 10.1038/nsmb.2461.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:11884616   PMID:14718166   PMID:15922569   PMID:18570454   PMID:22705305  


Genomics

Comparative Map Data
Hira
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21182,024,469 - 82,133,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,024,469 - 82,133,529 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,753,636 - 90,862,674 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01183,414,851 - 83,523,894 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01182,468,120 - 82,577,162 (-)NCBIRnor_WKY
Rnor_6.01186,168,196 - 86,276,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,168,196 - 86,276,430 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,270,162 - 89,378,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,805,603 - 80,913,841 (-)NCBICelera
Cytogenetic Map11q23NCBI
HIRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,330,698 - 19,431,733 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2219,330,698 - 19,447,450 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,318,221 - 19,419,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,698,224 - 17,799,219 (-)NCBINCBI36Build 36hg18NCBI36
Build 342217,692,777 - 17,793,773NCBI
Celera223,170,348 - 3,271,476 (-)NCBICelera
Cytogenetic Map22q11.21ENTREZGENE
HuRef222,938,779 - 3,039,800 (-)NCBIHuRef
CHM1_12219,317,795 - 19,418,793 (-)NCBICHM1_1
T2T-CHM13v2.02219,707,409 - 19,808,564 (-)NCBIT2T-CHM13v2.0
Hira
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,695,500 - 18,789,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,695,787 - 18,789,059 (+)EnsemblGRCm39 Ensembl
GRCm381618,876,750 - 18,970,309 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,877,037 - 18,970,309 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,876,843 - 18,970,402 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,790,313 - 18,883,872 (+)NCBIMGSCv36mm8
Celera1619,450,807 - 19,544,362 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.69NCBI
LOC102009660
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,581,370 - 18,673,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544218,581,370 - 18,673,590 (+)NCBIChiLan1.0ChiLan1.0
LOC100977781
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12217,765,598 - 17,845,654 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,765,598 - 17,847,084 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0222,087,846 - 2,191,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
HIRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,777,984 - 29,867,992 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,778,086 - 29,867,559 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,733,351 - 29,822,268 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,179,782 - 31,268,951 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,179,884 - 31,268,655 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,227,072 - 29,316,422 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,852,492 - 28,941,149 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,939,424 - 30,028,570 (+)NCBIUU_Cfam_GSD_1.0
LOC101957075
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,372,372 - 139,471,877 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366193,282,173 - 3,380,151 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366193,282,170 - 3,380,151 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,029,126 - 51,102,409 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,029,117 - 51,102,409 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,596,123 - 54,669,440 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HIRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,324,050 - 6,424,999 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,324,253 - 6,425,641 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666085508,725 - 609,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101713307
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247479 - 95,643 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hira
239 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:325
Count of miRNA genes:206
Interacting mature miRNAs:241
Transcripts:ENSRNOT00000075164
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat

Markers in Region
D11Got81  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,126,584 - 82,126,804 (+)MAPPERmRatBN7.2
Rnor_6.01186,269,803 - 86,270,022NCBIRnor6.0
Rnor_5.01189,371,769 - 89,371,988UniSTSRnor5.0
Celera1180,907,218 - 80,907,437UniSTS
RH 3.4 Map11698.3RGD
RH 3.4 Map11698.3UniSTS
BE115254  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,091,728 - 82,091,892 (+)MAPPERmRatBN7.2
Rnor_6.01185,870,299 - 85,870,462NCBIRnor6.0
Rnor_6.01186,235,449 - 86,235,612NCBIRnor6.0
Rnor_5.01189,337,415 - 89,337,578UniSTSRnor5.0
Rnor_5.01188,970,630 - 88,970,793UniSTSRnor5.0
Celera1180,872,849 - 80,873,012UniSTS
RH 3.4 Map11694.1UniSTS
Hira  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,132,470 - 82,132,627 (+)MAPPERmRatBN7.2
Rnor_6.01186,275,689 - 86,275,845NCBIRnor6.0
Rnor_5.01189,377,655 - 89,377,811UniSTSRnor5.0
Celera1180,913,100 - 80,913,256UniSTS
Cytogenetic Map11p12UniSTS
D22S1095E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21182,024,581 - 82,024,683 (+)MAPPERmRatBN7.2
Rnor_6.01185,802,649 - 85,802,750NCBIRnor6.0
Rnor_6.01186,168,309 - 86,168,410NCBIRnor6.0
Rnor_5.01189,270,275 - 89,270,376UniSTSRnor5.0
Rnor_5.01188,902,980 - 88,903,081UniSTSRnor5.0
Celera1180,805,716 - 80,805,817UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 24 21 12 18 12 74 20 33 11
Below cutoff 19 34 27 1 27 8 11 15 8 8

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001135760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006248641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088555 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005491052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000071462   ⟹   ENSRNOP00000065274
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1182,024,469 - 82,133,529 (-)Ensembl
Rnor_6.0 Ensembl1185,802,605 - 85,895,613 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000075164   ⟹   ENSRNOP00000064357
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1182,024,469 - 82,133,212 (-)Ensembl
Rnor_6.0 Ensembl1186,168,196 - 86,276,430 (-)Ensembl
RefSeq Acc Id: NM_001135760   ⟹   NP_001129232
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,133,212 (-)NCBI
Rnor_6.01186,168,196 - 86,276,430 (-)NCBI
Rnor_5.01189,270,162 - 89,378,396 (-)NCBI
Celera1180,805,603 - 80,913,841 (-)RGD
Sequence:
RefSeq Acc Id: XM_039088549   ⟹   XP_038944477
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,131,777 (-)NCBI
RefSeq Acc Id: XM_039088550   ⟹   XP_038944478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,132,606 (-)NCBI
RefSeq Acc Id: XM_039088551   ⟹   XP_038944479
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,131,676 (-)NCBI
RefSeq Acc Id: XM_039088552   ⟹   XP_038944480
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,132,589 (-)NCBI
RefSeq Acc Id: XM_039088554   ⟹   XP_038944482
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,132,608 (-)NCBI
RefSeq Acc Id: XM_039088555   ⟹   XP_038944483
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,131,676 (-)NCBI
RefSeq Acc Id: XM_039088556   ⟹   XP_038944484
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,131,676 (-)NCBI
RefSeq Acc Id: XM_039088557   ⟹   XP_038944485
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,132,608 (-)NCBI
RefSeq Acc Id: XM_039088558   ⟹   XP_038944486
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,115,477 (-)NCBI
RefSeq Acc Id: XM_039088559   ⟹   XP_038944487
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,024,469 - 82,113,717 (-)NCBI
RefSeq Acc Id: XR_005491052
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21182,048,391 - 82,131,676 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001129232   ⟸   NM_001135760
- UniProtKB: M0R4R2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000064357   ⟸   ENSRNOT00000075164
RefSeq Acc Id: XP_038944482   ⟸   XM_039088554
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038944485   ⟸   XM_039088557
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038944478   ⟸   XM_039088550
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038944480   ⟸   XM_039088552
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038944477   ⟸   XM_039088549
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038944483   ⟸   XM_039088555
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038944479   ⟸   XM_039088551
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038944484   ⟸   XM_039088556
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038944486   ⟸   XM_039088558
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038944487   ⟸   XM_039088559
- Peptide Label: isoform X9
RefSeq Acc Id: ENSRNOP00000065274   ⟸   ENSRNOT00000071462
Protein Domains
Hira

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R756-F1-model_v2 AlphaFold M0R756 1-1010 view protein structure
AF-M0R4R2-F1-model_v2 AlphaFold M0R4R2 1-1015 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698294
Promoter ID:EPDNEW_R8817
Type:multiple initiation site
Name:Hira_1
Description:histone cell cycle regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01186,275,971 - 86,276,031EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584950 AgrOrtholog
BioCyc Gene G2FUF-20678 BioCyc
Ensembl Genes ENSRNOG00000045770 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000049255 Ensembl
Ensembl Protein ENSRNOP00000064357 ENTREZGENE
  ENSRNOP00000064357.1 UniProtKB/TrEMBL
  ENSRNOP00000065274.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071462.3 UniProtKB/TrEMBL
  ENSRNOT00000075164 ENTREZGENE
  ENSRNOT00000075164.2 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro HIR1 UniProtKB/TrEMBL
  Hira UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:363849 UniProtKB/TrEMBL
NCBI Gene 363849 ENTREZGENE
PANTHER PTHR13831 UniProtKB/TrEMBL
Pfam Hira UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Hira PhenoGen
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt M0R4R2 ENTREZGENE, UniProtKB/TrEMBL
  M0R756_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Hira  histone cell cycle regulator  LOC100911837  protein HIRA-like  Data Merged 737654 PROVISIONAL
2013-09-16 Hira  histone cell cycle regulator  Hira  HIR histone cell cycle regulation defective homolog A (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911837  protein HIRA-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-12-01 Hira  HIR histone cell cycle regulation defective homolog A (S. cerevisiae)  LOC363849  similar to histone cell cycle regulation defective homolog A isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC363849  similar to histone cell cycle regulation defective homolog A isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL