LOC100977781 (protein HIRA) - Rat Genome Database

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Gene: LOC100977781 (protein HIRA) Pan paniscus
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Symbol: LOC100977781 (Ensembl: HIRA)
Name: protein HIRA (Ensembl:histone cell cycle regulator)
RGD ID: 11873644
Description: ENCODES a protein that exhibits histone binding (inferred); nucleosome binding (inferred); RNA polymerase II-specific DNA-binding transcription factor binding (inferred); INVOLVED IN gastrulation (ortholog); muscle cell differentiation (ortholog); osteoblast differentiation (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); Cardiac Fibrosis (ortholog); FOUND IN chromatin (inferred); HIR complex (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: HIR histone cell cycle regulation defective homolog A; HIRA
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22328,955,170 - 29,056,833 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,498,613 - 31,604,572 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,087,846 - 2,191,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,765,598 - 17,845,654 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,765,598 - 17,847,084 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
LOC100977781
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22328,955,170 - 29,056,833 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12231,498,613 - 31,604,572 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0222,087,846 - 2,191,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12217,765,598 - 17,845,654 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2217,765,598 - 17,847,084 (-)Ensemblpanpan1.1panPan2
HIRA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382219,330,698 - 19,431,733 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2219,330,698 - 19,447,450 (-)EnsemblGRCh38hg38GRCh38
GRCh372219,318,221 - 19,419,256 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362217,698,224 - 17,799,219 (-)NCBINCBI36Build 36hg18NCBI36
Build 342217,692,777 - 17,793,773NCBI
Celera223,170,348 - 3,271,476 (-)NCBICelera
Cytogenetic Map22q11.21ENTREZGENE
HuRef222,938,779 - 3,039,800 (-)NCBIHuRef
CHM1_12219,317,795 - 19,418,793 (-)NCBICHM1_1
T2T-CHM13v2.02219,707,409 - 19,808,564 (-)NCBIT2T-CHM13v2.0
Hira
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391618,695,500 - 18,789,059 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1618,695,787 - 18,789,059 (+)EnsemblGRCm39 Ensembl
GRCm381618,876,750 - 18,970,309 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1618,877,037 - 18,970,309 (+)EnsemblGRCm38mm10GRCm38
MGSCv371618,876,843 - 18,970,402 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361618,790,313 - 18,883,872 (+)NCBIMGSCv36mm8
Celera1619,450,807 - 19,544,362 (+)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.69NCBI
Hira
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81195,528,831 - 95,637,565 (-)NCBIGRCr8
mRatBN7.21182,024,469 - 82,133,212 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,024,469 - 82,133,529 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,753,636 - 90,862,674 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,414,851 - 83,523,894 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01182,468,120 - 82,577,162 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01186,168,196 - 86,276,430 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1186,168,196 - 86,276,430 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01189,270,162 - 89,378,396 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1180,805,603 - 80,913,841 (-)NCBICelera
Cytogenetic Map11q23NCBI
LOC102009660
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544218,581,370 - 18,673,761 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544218,581,370 - 18,673,590 (+)NCBIChiLan1.0ChiLan1.0
HIRA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12629,777,984 - 29,867,992 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2629,778,086 - 29,867,559 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2629,733,351 - 29,822,268 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02631,179,782 - 31,268,951 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2631,179,884 - 31,268,655 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12629,227,072 - 29,316,422 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02628,852,492 - 28,941,149 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,939,424 - 30,028,570 (+)NCBIUU_Cfam_GSD_1.0
LOC101957075
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118139,372,372 - 139,471,877 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366193,282,173 - 3,380,151 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366193,282,170 - 3,380,151 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HIRA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1451,029,126 - 51,102,409 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11451,029,117 - 51,102,409 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21454,596,123 - 54,669,440 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HIRA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1196,324,050 - 6,424,999 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl196,324,253 - 6,425,641 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666085508,725 - 609,791 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101713307
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247479 - 95,643 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSPPAT00000052098   ⟹   ENSPPAP00000029248
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2217,765,598 - 17,845,639 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000052142   ⟹   ENSPPAP00000029293
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2217,766,342 - 17,847,084 (-)Ensembl
RefSeq Acc Id: XM_034949220   ⟹   XP_034805111
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,955,170 - 29,056,529 (-)NCBI
NHGRI_mPanPan12231,498,615 - 31,604,247 (-)NCBI
Mhudiblu_PPA_v0222,087,846 - 2,190,999 (-)NCBI
RefSeq Acc Id: XM_034949221   ⟹   XP_034805112
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,955,170 - 29,056,682 (-)NCBI
NHGRI_mPanPan12231,500,404 - 31,604,401 (-)NCBI
Mhudiblu_PPA_v0222,087,846 - 2,191,008 (-)NCBI
RefSeq Acc Id: XM_034949223   ⟹   XP_034805114
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,955,170 - 29,033,525 (-)NCBI
NHGRI_mPanPan12231,498,614 - 31,581,223 (-)NCBI
Mhudiblu_PPA_v0222,087,846 - 2,167,845 (-)NCBI
RefSeq Acc Id: XM_034949226   ⟹   XP_034805117
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,955,170 - 29,056,833 (-)NCBI
NHGRI_mPanPan12231,498,614 - 31,604,572 (-)NCBI
Mhudiblu_PPA_v0222,087,846 - 2,191,192 (-)NCBI
RefSeq Acc Id: XM_055105605   ⟹   XP_054961580
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,955,170 - 29,045,781 (-)NCBI
NHGRI_mPanPan12231,498,614 - 31,593,497 (-)NCBI
RefSeq Acc Id: XM_055105608   ⟹   XP_054961583
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22328,955,170 - 29,030,783 (-)NCBI
NHGRI_mPanPan12231,498,613 - 31,578,481 (-)NCBI
RefSeq Acc Id: XP_034805117   ⟸   XM_034949226
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BIW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034805112   ⟸   XM_034949221
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BIW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034805111   ⟸   XM_034949220
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BIW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034805114   ⟸   XM_034949223
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BIW5 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000029248   ⟸   ENSPPAT00000052098
RefSeq Acc Id: ENSPPAP00000029293   ⟸   ENSPPAT00000052142
RefSeq Acc Id: XP_054961583   ⟸   XM_055105608
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054961580   ⟸   XM_055105605
- Peptide Label: isoform X2

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000037592 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000052098.1 UniProtKB/TrEMBL
  ENSPPAT00000052142.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro HIR1 UniProtKB/TrEMBL
  Hira UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene LOC100977781 ENTREZGENE
PANTHER PROTEIN HIRA UniProtKB/TrEMBL
  PTHR13831 UniProtKB/TrEMBL
Pfam Hira UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A2R9BIS6_PANPA UniProtKB/TrEMBL
  A0A2R9BIW5 ENTREZGENE, UniProtKB/TrEMBL