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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:amiodarone
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Accession:CHEBI:2663 term browser browse the term
Definition:A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Synonyms:exact_synonym: (2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
 related_synonym: 2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran;   2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone;   2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran;   Formula=C25H29I2NO3;   InChI=1S/C25H29I2NO3/c1-4-7-11-22-23(18-10-8-9-12-21(18)31-22)24(29)17-15-19(26)25(20(27)16-17)30-14-13-28(5-2)6-3/h8-10,12,15-16H,4-7,11,13-14H2,1-3H3;   InChIKey=IYIKLHRQXLHMJQ-UHFFFAOYSA-N;   SMILES=CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1;   amiodarona;   amiodaronum
 xref: Beilstein:1271711;   CAS:1951-25-3;   DrugBank:DB01118;   Drug_Central:176;   HMDB:HMDB0015250;   KEGG:C06823;   KEGG:D02910;   LINCS:LSM-2379
 xref_mesh: MESH:D000638
 xref: PMID:10188629;   PMID:16479044;   PMID:18368867;   Patent:CA2826272;   Patent:TW201400111;   Wikipedia:Amiodarone


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amiodarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase affects expression EXP Amiodarone affects the expression of AADAT mRNA CTD PMID:18355885 NCBI chr16:29,509,392...29,544,332
Ensembl chr16:29,509,394...29,544,332 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 decreases expression ISO Amiodarone results in decreased expression of ABCA1 mRNA CTD PMID:29248575 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca2 ATP binding cassette subfamily A member 2 increases expression ISO Amiodarone results in increased expression of ABCA2 mRNA CTD PMID:19774075 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
decreases expression		 ISO
EXP		 Amiodarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Amiodarone results in decreased activity of ABCB11 protein
Amiodarone results in decreased expression of ABCB11 mRNA		 CTD PMID:20829430 PMID:24014644 PMID:27765674 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
affects response to substance
affects expression		 ISO
EXP		 Amiodarone inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Daunorubicin]; Amiodarone inhibits the reaction [ABCB1 protein results in increased transport of Digoxin]
Amiodarone results in decreased activity of ABCB1 protein
ABCB1A protein affects the susceptibility to Amiodarone
Amiodarone inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Amiodarone affects the expression of ABCB1 mRNA; Amiodarone affects the expression of ABCB1A mRNA		 CTD PMID:11231118 PMID:12235267 PMID:15502009 PMID:18355885 PMID:19483382 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects response to substance ISO ABCB1B protein affects the susceptibility to Amiodarone CTD PMID:15502009 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression
decreases expression		 ISO
EXP		 Amiodarone results in increased expression of ABCB4 mRNA
Amiodarone results in decreased expression of ABCB4 mRNA		 CTD PMID:24489787 PMID:27765674 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Amiodarone results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
decreases expression		 ISO
EXP		 Amiodarone results in increased expression of ABCC3 mRNA
Amiodarone results in decreased expression of ABCC3 mRNA		 CTD PMID:24489787 PMID:27765674 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 decreases expression EXP Amiodarone results in decreased expression of ABCC4 mRNA CTD PMID:27765674 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 affects expression EXP Amiodarone affects the expression of ABCC6 mRNA CTD PMID:19483382 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Abcd3 ATP binding cassette subfamily D member 3 increases expression ISO Amiodarone results in increased expression of ABCD3 mRNA CTD PMID:24489787 NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020 		JBrowse link
G Abcd4 ATP binding cassette subfamily D member 4 increases expression ISO Amiodarone results in increased expression of ABCD4 mRNA CTD PMID:24489787 NCBI chr 6:104,246,459...104,260,965
Ensembl chr 6:104,246,468...104,280,276 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression
increases expression		 EXP Amiodarone affects the expression of ABCG5 mRNA
Amiodarone results in increased expression of ABCG5 mRNA		 CTD PMID:19483382 PMID:27765674 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Amiodarone affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514 		JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Amiodarone affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119 		JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Amiodarone affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Amiodarone results in increased expression of ABL1 mRNA CTD PMID:19774075 NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065 		JBrowse link
G Acaa1b acetyl-Coenzyme A acyltransferase 1B increases expression ISO Amiodarone results in increased expression of ACAA1 mRNA CTD PMID:15265979 NCBI chr 8:118,872,996...118,881,852
Ensembl chr 8:118,872,997...118,881,825 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression
increases expression		 EXP
ISO		 Amiodarone affects the expression of ACACA mRNA
Amiodarone results in increased expression of ACACA mRNA		 CTD PMID:19483382 PMID:19774075 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acacb acetyl-CoA carboxylase beta increases expression EXP
ISO		 Amiodarone results in increased expression of ACACB mRNA CTD PMID:19224547 PMID:24489787 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Acad10 acyl-CoA dehydrogenase family, member 10 increases expression ISO Amiodarone results in increased expression of ACAD10 mRNA CTD PMID:24535564 NCBI chr12:34,901,211...34,943,973
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Acad9 acyl-CoA dehydrogenase family, member 9 increases expression ISO Amiodarone results in increased expression of ACAD9 mRNA CTD PMID:24489787 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Amiodarone affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO Amiodarone results in increased expression of ACADM mRNA CTD PMID:24489787 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 increases expression ISO Amiodarone results in increased expression of ACAT1 mRNA CTD PMID:24489787 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression EXP Amiodarone results in increased expression of ACAT2 mRNA CTD PMID:32084307 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acer2 alkaline ceramidase 2 increases expression EXP Amiodarone results in increased expression of ACER2 mRNA CTD PMID:25580480 NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614 		JBrowse link
G Acly ATP citrate lyase increases expression ISO
EXP		 Amiodarone results in increased expression of ACLY mRNA CTD PMID:32084307 PMID:32535746 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320 		JBrowse link
G Aco1 aconitase 1 affects expression EXP Amiodarone affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Aco2 aconitase 2 affects expression EXP Amiodarone affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acot1 acyl-CoA thioesterase 1 increases expression ISO
EXP		 Amiodarone results in increased expression of ACOT1 mRNA CTD PMID:24489787 PMID:24535564 PMID:30685923 PMID:32084307 NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163 		JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression
increases expression		 EXP
ISO		 Amiodarone affects the expression of ACOT12 mRNA
Amiodarone results in increased expression of ACOT12 mRNA		 CTD PMID:19483382 PMID:24489787 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Amiodarone results in increased expression of ACOT2 mRNA CTD PMID:24489787 PMID:24535564 PMID:30685923 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot3 acyl-CoA thioesterase 3 increases expression ISO Amiodarone results in increased expression of ACOT3 mRNA CTD PMID:24535564 NCBI chr 6:103,682,518...103,688,735
Ensembl chr 6:103,682,596...103,688,427
Ensembl chr 6:103,682,596...103,688,427 		JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Amiodarone affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917 		JBrowse link
G Acot8 acyl-CoA thioesterase 8 increases expression ISO Amiodarone results in increased expression of ACOT8 mRNA CTD PMID:19774075 NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851 		JBrowse link
G Acox1 acyl-CoA oxidase 1 increases expression ISO Amiodarone results in increased expression of ACOX1 mRNA CTD PMID:15265979 PMID:30685923 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Acox2 acyl-CoA oxidase 2 increases expression ISO Amiodarone results in increased expression of ACOX2 mRNA CTD PMID:24489787 NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160 		JBrowse link
G Acsf3 acyl-CoA synthetase family member 3 increases expression ISO Amiodarone results in increased expression of ACSF3 mRNA CTD PMID:19774075 NCBI chr19:50,835,116...50,875,557
Ensembl chr19:50,835,221...50,875,553 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 increases expression EXP Amiodarone results in increased expression of ACSL3 mRNA CTD PMID:32084307 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 increases expression ISO
EXP		 Amiodarone results in increased expression of ACSS2 mRNA CTD PMID:24535564 PMID:32084307 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 mRNA]; SB 203580 inhibits the reaction [Amiodarone results in increased expression of ACTA2 protein]
Amiodarone results in increased expression of ACTA2 mRNA; Amiodarone results in increased expression of ACTA2 protein		 CTD PMID:31071512 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actr3b actin related protein 3B increases expression ISO Amiodarone results in increased expression of ACTR3B mRNA CTD PMID:19774075 NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441 		JBrowse link
G Acvr1b activin A receptor type 1B increases expression ISO Amiodarone results in increased expression of ACVR1B mRNA CTD PMID:19774075 NCBI chr 7:132,286,266...132,329,679
Ensembl chr 7:132,286,275...132,329,673 		JBrowse link
G Acyp1 acylphosphatase 1 increases expression ISO Amiodarone results in increased expression of ACYP1 mRNA CTD PMID:19774075 NCBI chr 6:104,919,162...104,932,348
Ensembl chr 6:104,919,162...104,932,387 		JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Amiodarone affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113 		JBrowse link
G Add1 adducin 1 affects expression EXP Amiodarone affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182 		JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO Amiodarone results in increased expression of ADGRD1 mRNA CTD PMID:19774075 NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696 		JBrowse link
G Adgrf1 adhesion G protein-coupled receptor F1 decreases expression ISO Amiodarone results in decreased expression of ADGRF1 mRNA CTD PMID:24535564 NCBI chr 9:17,661,258...17,696,359
Ensembl chr 9:17,660,930...17,711,704 		JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Amiodarone affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adm2 adrenomedullin 2 multiple interactions ISO ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD1 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of SOD2 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF mRNA]] CTD PMID:34434487 NCBI chr 7:120,393,179...120,394,965
Ensembl chr 7:120,393,179...120,396,331 		JBrowse link
G Adora3 adenosine A3 receptor increases expression ISO Amiodarone results in increased expression of ADORA3 mRNA CTD PMID:19774075 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357 		JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression ISO Amiodarone results in increased expression of ADRA2A mRNA CTD PMID:19774075 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adrb1 adrenoceptor beta 1 decreases expression ISO Amiodarone results in decreased expression of ADRB1 protein CTD PMID:1653643 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 decreases expression ISO Amiodarone results in decreased expression of ADRB2 protein CTD PMID:1653643 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Adrb3 adrenoceptor beta 3 multiple interactions EXP Amiodarone inhibits the reaction [Triiodothyronine results in decreased expression of ADRB3 protein] CTD PMID:10217540 NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552 		JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Amiodarone affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:22,907,758...22,993,834
Ensembl chr17:22,930,740...22,993,826 		JBrowse link
G Afm afamin affects expression EXP Amiodarone affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870 		JBrowse link
G Afp alpha-fetoprotein increases expression ISO Amiodarone results in increased expression of AFP mRNA CTD PMID:24489787 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agt angiotensinogen increases expression
multiple interactions
affects expression		 ISO
EXP		 Amiodarone results in increased expression of AGT mRNA; Amiodarone results in increased expression of AGT protein
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA]
Amiodarone affects the expression of AGT mRNA		 CTD PMID:17214612 PMID:19483382 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Amiodarone affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Amiodarone results in increased expression of AHNAK mRNA CTD PMID:19774075 NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926 		JBrowse link
G Ahr aryl hydrocarbon receptor affects expression ISO Amiodarone affects the expression of AHR mRNA CTD PMID:35641671 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases expression ISO Amiodarone results in increased expression of AIFM1 mRNA CTD PMID:24489787 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ak4 adenylate kinase 4 increases expression EXP Amiodarone results in increased expression of AK4 protein CTD PMID:16538043 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Amiodarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Amiodarone results in increased expression of AKR1C1 mRNA CTD PMID:21163907 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Amiodarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909 		JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Amiodarone affects the expression of AKR7A3 mRNA CTD PMID:19483382 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Amiodarone results in decreased phosphorylation of AKT1 protein CTD PMID:23912912 PMID:26515726 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO Amiodarone results in increased expression of ALAS1 mRNA CTD PMID:19774075 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression ISO Amiodarone results in decreased expression of ALAS2 mRNA CTD PMID:24535564 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Alb albumin increases expression ISO Amiodarone results in increased expression of ALB mRNA CTD PMID:19774075 PMID:36586010 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Amiodarone affects the expression of ALDH1A1 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Amiodarone affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression ISO Amiodarone results in increased expression of ALDH3A2 mRNA CTD PMID:24535564 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281 		JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 increases expression EXP Amiodarone results in increased expression of ALDH6A1 mRNA CTD PMID:17991464 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656 		JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase increases expression ISO Amiodarone results in increased expression of ALG12 mRNA CTD PMID:19774075 NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458 		JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase increases expression ISO Amiodarone results in increased expression of ALG2 mRNA CTD PMID:19774075 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297 		JBrowse link
G Alk ALK receptor tyrosine kinase increases expression ISO Amiodarone results in increased expression of ALK mRNA CTD PMID:19774075 NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034 		JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression ISO Amiodarone results in increased expression of ALKAL1 mRNA CTD PMID:19774075 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948 		JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Amiodarone affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044 		JBrowse link
G Amigo1 adhesion molecule with Ig like domain 1 increases expression ISO Amiodarone results in increased expression of AMIGO1 mRNA CTD PMID:19774075 NCBI chr 2:195,823,138...195,828,593
Ensembl chr 2:195,823,042...195,829,585 		JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Amiodarone results in decreased expression of ANGPTL3 mRNA CTD PMID:27089845 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Amiodarone results in increased expression of ANGPTL4 mRNA CTD PMID:24489787 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Anxa4 annexin A4 increases expression ISO Amiodarone results in increased expression of ANXA4 mRNA CTD PMID:19774075 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression
increases expression		 ISO Amiodarone results in decreased expression of AP1S1 mRNA
Amiodarone results in increased expression of AP1S1 mRNA		 CTD PMID:17175557 PMID:17567588 PMID:29248575 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Amiodarone affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140 		JBrowse link
G Apcs amyloid P component, serum affects expression EXP Amiodarone affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:85,373,219...85,374,195
Ensembl chr13:85,373,220...85,374,298 		JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Amiodarone affects the expression of APOA4 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apoa5 apolipoprotein A5 increases expression ISO Amiodarone results in increased expression of APOA5 mRNA CTD PMID:24489787 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816 		JBrowse link
G Apob apolipoprotein B decreases expression ISO Amiodarone results in decreased expression of APOB mRNA CTD PMID:29248575 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc2 apolipoprotein C2 increases expression ISO Amiodarone results in increased expression of APOC2 mRNA CTD PMID:24489787 NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476 		JBrowse link
G Apoe apolipoprotein E decreases expression EXP Amiodarone results in decreased expression of APOE mRNA CTD PMID:17991464 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Apoh apolipoprotein H affects expression EXP Amiodarone affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G Apool apolipoprotein O-like affects expression EXP Amiodarone affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:77,377,723...77,443,672
Ensembl chr  X:77,377,781...77,443,900 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression ISO Amiodarone results in increased expression of ARC mRNA CTD PMID:19774075 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arg1 arginase 1 affects expression EXP Amiodarone affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arhgap15 Rho GTPase activating protein 15 increases expression ISO Amiodarone results in increased expression of ARHGAP15 mRNA CTD PMID:19774075 NCBI chr 3:27,989,368...28,592,722
Ensembl chr 3:27,989,633...28,600,265 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 increases expression ISO Amiodarone results in increased expression of ARHGAP35 mRNA CTD PMID:19774075 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Arhgap4 Rho GTPase activating protein 4 increases expression ISO Amiodarone results in increased expression of ARHGAP4 mRNA CTD PMID:19774075 NCBI chr  X:151,636,071...151,651,528
Ensembl chr  X:151,632,454...151,651,128 		JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases expression ISO Amiodarone results in increased expression of ARHGAP45 mRNA CTD PMID:19774075 NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268 		JBrowse link
G Arhgap9 Rho GTPase activating protein 9 increases expression ISO Amiodarone results in increased expression of ARHGAP9 mRNA CTD PMID:19774075 NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524 		JBrowse link
G Arhgef10l Rho guanine nucleotide exchange factor 10 like increases expression ISO Amiodarone results in increased expression of ARHGEF10L mRNA CTD PMID:19774075 NCBI chr 5:152,792,247...152,935,255
Ensembl chr 5:152,792,252...152,919,538 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 increases expression ISO Amiodarone results in increased expression of ARHGEF7 mRNA CTD PMID:19774075 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 increases expression ISO Amiodarone results in increased expression of ARHGEF9 mRNA CTD PMID:19774075 NCBI chr  X:59,919,560...60,077,538
Ensembl chr  X:59,920,870...60,077,513 		JBrowse link
G Arid5a AT-rich interaction domain 5A increases expression ISO Amiodarone results in increased expression of ARID5A mRNA CTD PMID:19774075 NCBI chr 9:38,534,612...38,549,467
Ensembl chr 9:38,534,590...38,547,597 		JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 affects expression EXP Amiodarone affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994 		JBrowse link
G Armc9 armadillo repeat containing 9 increases expression ISO Amiodarone results in increased expression of ARMC9 mRNA CTD PMID:19774075 NCBI chr 9:86,802,791...86,928,611
Ensembl chr 9:86,802,868...86,928,860 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Amiodarone results in increased expression of ARPC4 mRNA CTD PMID:19774075 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression EXP
ISO		 Amiodarone results in increased expression of ASAH1 mRNA CTD PMID:15342952 PMID:17567588 PMID:19224547 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asb7 ankyrin repeat and SOCS box-containing 7 increases expression ISO Amiodarone results in increased expression of ASB7 mRNA CTD PMID:19774075 NCBI chr 1:120,222,835...120,267,411
Ensembl chr 1:120,222,745...120,267,282 		JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Amiodarone affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Amiodarone results in increased expression of ASNS mRNA CTD PMID:17175557 PMID:17567588 PMID:36586010 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions		 ISO Amiodarone results in increased expression of ATF3 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone promotes the reaction [Amiodarone results in increased expression of ATF3 mRNA]		 CTD PMID:19774075 PMID:34259586 PMID:36586010 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
decreases expression		 ISO Amiodarone results in increased expression of ATF4 mRNA; Amiodarone results in increased expression of ATF4 protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of ATF4 mRNA]
Amiodarone results in decreased expression of ATF4 mRNA		 CTD PMID:21292685 PMID:28962527 PMID:34259586 PMID:35641671 PMID:36586010 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Amiodarone affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707 		JBrowse link
G Atf6 activating transcription factor 6 multiple interactions ISO Amiodarone results in increased expression of and affects the localization of ATF6 protein CTD PMID:28962527 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atf6b activating transcription factor 6 beta increases expression ISO Amiodarone results in increased expression of ATF6B mRNA CTD PMID:19774075 NCBI chr20:4,090,921...4,098,920
Ensembl chr20:4,090,921...4,098,894 		JBrowse link
G Atg5 autophagy related 5 affects response to substance ISO ATG5 protein affects the susceptibility to Amiodarone CTD PMID:32651653 NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209 		JBrowse link
G Atg7 autophagy related 7 increases expression
multiple interactions
affects response to substance		 ISO Amiodarone results in increased expression of ATG7 protein
ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]
ATG7 protein affects the susceptibility to Amiodarone		 CTD PMID:23912912 PMID:32651653 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Atoh1 atonal bHLH transcription factor 1 increases expression ISO Amiodarone results in increased expression of ATOH1 mRNA CTD PMID:19774075 NCBI chr 4:93,912,068...93,914,163
Ensembl chr 4:93,912,068...93,914,154 		JBrowse link
G Atp11c ATPase phospholipid transporting 11C increases expression ISO Amiodarone results in increased expression of ATP11C mRNA CTD PMID:19774075 NCBI chr  X:138,564,459...138,752,116
Ensembl chr  X:138,565,836...138,751,204 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Amiodarone results in decreased expression of ATP1A1 protein CTD PMID:8071999 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression EXP Amiodarone results in decreased expression of ATP1A2 mRNA; Amiodarone results in decreased expression of ATP1A2 protein CTD PMID:7573397 PMID:8071999 PMID:12479229 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 decreases expression EXP Amiodarone results in decreased expression of ATP1B1 protein CTD PMID:8071999 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Amiodarone results in decreased expression of ATP1B2 mRNA CTD PMID:8071999 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 decreases expression EXP Amiodarone results in decreased expression of ATP2A2 mRNA CTD PMID:17535870 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta increases expression EXP Amiodarone results in increased expression of ATP5F1B mRNA CTD PMID:17991464 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Amiodarone affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450 		JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Amiodarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Amiodarone affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Amiodarone affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Amiodarone affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bag1 BAG cochaperone 1 increases expression ISO Amiodarone results in increased expression of BAG1 mRNA CTD PMID:19774075 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Bag3 BAG cochaperone 3 decreases expression EXP Amiodarone results in decreased expression of BAG3 mRNA CTD PMID:17991464 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Baiap2l1 BAR/IMD domain containing adaptor protein 2 like 1 increases expression ISO Amiodarone results in increased expression of BAIAP2L1 mRNA CTD PMID:19774075 NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO Amiodarone results in increased expression of BAX mRNA; Amiodarone results in increased expression of BAX protein
ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]		 CTD PMID:12084619 PMID:34434487 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Amiodarone results in increased expression of BBC3 mRNA CTD PMID:36586010 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bbox1 gamma-butyrobetaine hydroxylase 1 increases expression ISO Amiodarone results in increased expression of BBOX1 mRNA CTD PMID:19774075 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458 		JBrowse link
G Bckdha branched chain keto acid dehydrogenase E1 subunit alpha increases expression EXP Amiodarone results in increased expression of BCKDHA protein CTD PMID:16538043 NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 EXP
ISO		 Amiodarone results in decreased expression of BCL2 protein
[3-methyladenine co-treated with Amiodarone] results in decreased expression of BCL2 protein; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]
Amiodarone results in decreased expression of BCL2 mRNA; Amiodarone results in decreased expression of BCL2 protein		 CTD PMID:21224497 PMID:23912912 PMID:34434487 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression ISO Amiodarone results in increased expression of BCL2L11 mRNA CTD PMID:19774075 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression EXP Amiodarone results in increased expression of BCL3 mRNA CTD PMID:22015988 NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607 		JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Amiodarone affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974 		JBrowse link
G Bco1 beta-carotene oxygenase 1 decreases expression ISO Amiodarone results in decreased expression of BCO1 mRNA CTD PMID:24535564 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101 		JBrowse link
G Bdnf brain-derived neurotrophic factor affects expression EXP Amiodarone affects the expression of BDNF mRNA CTD PMID:31324950 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Amiodarone results in increased expression of BHLHE40 mRNA CTD PMID:19774075 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Bhmt betaine-homocysteine S-methyltransferase affects expression EXP Amiodarone affects the expression of BHMT mRNA CTD PMID:18355885 NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [TNFSF10 co-treated with Amiodarone] results in increased cleavage of BID protein CTD PMID:21292685 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression EXP Amiodarone results in decreased expression of BIRC5 protein CTD PMID:21224497 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bltp3b bridge-like lipid transfer protein family member 3B affects expression EXP Amiodarone affects the expression of BLTP3B mRNA CTD PMID:19483382 NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720 		JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Amiodarone affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bmp2k BMP-2 inducible kinase increases expression ISO Amiodarone results in increased expression of BMP2K mRNA CTD PMID:19774075 NCBI chr14:12,481,194...12,579,411
Ensembl chr14:12,484,729...12,579,134 		JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Amiodarone affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bola2 bolA family member 2 increases expression ISO Amiodarone results in increased expression of BOLA2 mRNA CTD PMID:19774075 NCBI chr 1:181,291,967...181,292,833
Ensembl chr 1:181,291,398...181,292,676 		JBrowse link
G Boll boule homolog, RNA binding protein increases expression ISO Amiodarone results in increased expression of BOLL mRNA CTD PMID:19774075 NCBI chr 9:56,734,890...56,859,917
Ensembl chr 9:56,733,584...56,859,916 		JBrowse link
G Brca1 BRCA1, DNA repair associated increases expression ISO Amiodarone results in increased expression of BRCA1 mRNA CTD PMID:24489787 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brcc3 BRCA1/BRCA2-containing complex subunit 3 increases expression ISO Amiodarone results in increased expression of BRCC3 mRNA CTD PMID:19774075 NCBI chr 9:1,986,942...1,989,484
Ensembl chr 9:1,986,575...1,991,080 		JBrowse link
G Brpf1 bromodomain and PHD finger containing, 1 increases expression ISO Amiodarone results in increased expression of BRPF1 mRNA CTD PMID:19774075 NCBI chr 4:146,456,325...146,472,781
Ensembl chr 4:146,456,318...146,472,649 		JBrowse link
G Bsg basigin increases expression ISO Amiodarone results in increased expression of BSG mRNA CTD PMID:19774075 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Amiodarone affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879 		JBrowse link
G C11h21orf91 similar to human chromosome 21 open reading frame 91 increases expression ISO Amiodarone results in increased expression of C21ORF91 mRNA CTD PMID:19774075 NCBI chr11:17,229,129...17,262,307
Ensembl chr11:17,229,138...17,262,483 		JBrowse link
G C19h16orf74 similar to human chromosome 16 open reading frame 74 increases expression ISO Amiodarone results in increased expression of C16ORF74 mRNA CTD PMID:19774075 NCBI chr19:48,660,288...48,686,287
Ensembl chr19:48,660,288...48,686,349 		JBrowse link
G C1h11orf16 similar to human chromosome 11 open reading frame 16 increases expression ISO Amiodarone results in increased expression of C11ORF16 mRNA CTD PMID:19774075 NCBI chr 1:163,742,987...163,754,920
Ensembl chr 1:163,743,021...163,754,089 		JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Amiodarone affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G C1s complement C1s affects expression EXP Amiodarone affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303 		JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Amiodarone affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739 		JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression ISO Amiodarone results in increased expression of NLF2 mRNA CTD PMID:19774075 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328 		JBrowse link
G C2h3orf33 similar to human chromosome 3 open reading frame 33 increases expression ISO Amiodarone results in increased expression of C3ORF33 mRNA CTD PMID:19774075 NCBI chr 2:148,376,598...148,404,343
Ensembl chr 2:148,380,581...148,404,387 		JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression EXP Amiodarone affects the expression of C4BPA mRNA CTD PMID:19483382 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G C7 complement C7 affects expression EXP Amiodarone affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535 		JBrowse link
G C8b complement C8 beta chain affects expression
decreases expression		 EXP
ISO		 Amiodarone affects the expression of C8B mRNA
Amiodarone results in decreased expression of C8B mRNA		 CTD PMID:19483382 PMID:24535564 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565 		JBrowse link
G C8h3orf18 similar to human chromosome 3 open reading frame 18 increases expression ISO Amiodarone results in increased expression of C3ORF18 mRNA CTD PMID:19774075 NCBI chr 8:108,012,638...108,022,050
Ensembl chr 8:108,012,638...108,022,461 		JBrowse link
G C9h6orf141 similar to human chromosome 6 open reading frame 141 increases expression ISO Amiodarone results in increased expression of C6ORF141 mRNA CTD PMID:19774075 NCBI chr 9:20,024,916...20,029,094
Ensembl chr 9:20,024,916...20,029,094 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C decreases expression ISO Amiodarone results in decreased expression of CACNA1C mRNA CTD PMID:15520326 NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648 		JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Amiodarone affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829 		JBrowse link
G Calr calreticulin increases expression ISO Amiodarone results in increased expression of CALR mRNA CTD PMID:36586010 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha increases expression ISO Amiodarone results in increased expression of CAMK2A mRNA CTD PMID:19774075 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Capn11 calpain 11 increases expression ISO Amiodarone results in increased expression of CAPN11 mRNA CTD PMID:19774075 NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601 		JBrowse link
G Capn3 calpain 3 increases expression ISO Amiodarone results in increased expression of CAPN3 mRNA CTD PMID:19774075 NCBI chr 3:107,407,518...107,457,858
Ensembl chr 3:107,407,850...107,457,858 		JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Amiodarone affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502 		JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Amiodarone affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car3 carbonic anhydrase 3 affects expression
increases expression		 EXP Amiodarone affects the expression of CAR3 mRNA
Amiodarone results in increased expression of CAR3 protein		 CTD PMID:16538043 PMID:19483382 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Card9 caspase recruitment domain family, member 9 increases expression ISO Amiodarone results in increased expression of CARD9 mRNA CTD PMID:19774075 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Caskin2 cask-interacting protein 2 increases expression ISO Amiodarone results in increased expression of CASKIN2 mRNA CTD PMID:19774075 NCBI chr10:101,027,196...101,041,429
Ensembl chr10:101,027,260...101,041,414 		JBrowse link
G Casp3 caspase 3 affects expression
increases expression
multiple interactions
decreases expression
increases activity
increases cleavage		 EXP
ISO		 Amiodarone affects the expression of CASP3 mRNA
Amiodarone results in increased expression of CASP3 mRNA; Amiodarone results in increased expression of CASP3 protein
3-methyladenine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP3 protein; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]; alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP3 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]]; Amiodarone results in increased activity of and results in increased cleavage of CASP3 protein; ATG7 protein affects the reaction [Amiodarone results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Amiodarone results in increased cleavage of CASP3 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP3 protein]
Amiodarone results in decreased expression of CASP3 protein modified form		 CTD PMID:12084619 PMID:12747577 PMID:19483382 PMID:19815060 PMID:21224497 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity
increases expression		 ISO alpha-Tocopherol promotes the reaction [Amiodarone results in increased activity of CASP7 protein]; alpha-Tocopherol promotes the reaction [TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]]; TNF protein promotes the reaction [Amiodarone results in increased activity of CASP7 protein]
Amiodarone results in increased expression of CASP7 mRNA		 CTD PMID:23042730 PMID:23135547 PMID:24489787 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression		 ISO
EXP		 [TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP8 protein
Amiodarone results in increased expression of CASP8 protein modified form		 CTD PMID:21224497 PMID:21292685 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions		 ISO Amiodarone results in increased expression of CASP9 mRNA
[TNFSF10 co-treated with Amiodarone] results in increased cleavage of CASP9 protein
[Amiodarone co-treated with TNF protein] results in increased activity of CASP9 protein		 CTD PMID:19774075 PMID:21292685 PMID:23042730 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity		 EXP
ISO		 Amiodarone inhibits the reaction [Indomethacin results in increased activity of CAT protein]
ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased activity of CAT protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of CAT mRNA]]		 CTD PMID:18087811 PMID:34434487 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav3 caveolin 3 increases expression ISO Amiodarone results in increased expression of CAV3 mRNA CTD PMID:19774075 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP Amiodarone affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393
Ensembl chr11:32,908,950...32,911,393 		JBrowse link
G Ccdc134 coiled-coil domain containing 134 increases expression ISO Amiodarone results in increased expression of CCDC134 mRNA CTD PMID:19774075 NCBI chr 7:113,644,557...113,659,050
Ensembl chr 7:113,644,639...113,659,050 		JBrowse link
G Ccdc17 coiled-coil domain containing 17 increases expression ISO Amiodarone results in increased expression of CCDC17 mRNA CTD PMID:19774075 NCBI chr 5:130,051,158...130,056,676
Ensembl chr 5:130,045,938...130,056,673 		JBrowse link
G Ccdc9 coiled-coil domain containing 9 increases expression ISO Amiodarone results in increased expression of CCDC9 mRNA CTD PMID:19774075 NCBI chr 1:76,978,312...76,991,673
Ensembl chr 1:76,974,091...76,991,607 		JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression ISO Amiodarone results in increased expression of CFAP184 mRNA CTD PMID:19774075 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression		 ISO Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]
Amiodarone results in increased expression of CCL2 mRNA
[Amiodarone co-treated with Dexamethasone] results in increased expression of CCL2 mRNA		 CTD PMID:19225199 PMID:23397585 PMID:25900201 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression EXP Amiodarone results in increased expression of CCN2 mRNA CTD PMID:32909452 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnt1 cyclin T1 increases expression ISO Amiodarone results in increased expression of CCNT1 mRNA CTD PMID:19774075 NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871 		JBrowse link
G Ccr9 C-C motif chemokine receptor 9 increases expression ISO Amiodarone results in increased expression of CCR9 mRNA CTD PMID:19774075 NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969 		JBrowse link
G Cd320 CD320 molecule increases expression ISO Amiodarone results in increased expression of CD320 mRNA CTD PMID:19774075 NCBI chr 7:14,626,171...14,631,976
Ensembl chr 7:14,609,146...14,631,976 		JBrowse link
G Cd36 CD36 molecule increases expression
decreases expression		 ISO Amiodarone results in increased expression of CD36 mRNA; Amiodarone results in increased expression of CD36 protein
Amiodarone results in decreased expression of CD36 mRNA		 CTD PMID:24535564 PMID:29248575 PMID:32535746 PMID:34259586 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein CTD PMID:22785256 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cda cytidine deaminase increases expression ISO Amiodarone results in increased expression of CDA mRNA CTD PMID:24535564 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231 		JBrowse link
G Cdc25a cell division cycle 25A increases expression ISO Amiodarone results in increased expression of CDC25A mRNA CTD PMID:19774075 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc42se1 CDC42 small effector 1 increases expression ISO Amiodarone results in increased expression of CDC42SE1 mRNA CTD PMID:19774075 NCBI chr 2:182,805,691...182,813,520
Ensembl chr 2:182,804,925...182,814,028 		JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions		 ISO Amiodarone results in increased expression of CDH1 protein
6-bromoindirubin-3'-oxime inhibits the reaction [Amiodarone results in increased expression of CDH1 protein]		 CTD PMID:26515726 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh15 cadherin 15 increases expression ISO Amiodarone results in increased expression of CDH15 mRNA CTD PMID:19774075 NCBI chr19:50,903,757...50,927,151
Ensembl chr19:50,903,638...50,927,105 		JBrowse link
G Cdh2 cadherin 2 decreases expression ISO Amiodarone results in decreased expression of CDH2 protein CTD PMID:26515726 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdh26 cadherin 26 increases expression ISO Amiodarone results in increased expression of CDH26 mRNA CTD PMID:19774075 NCBI chr 3:165,520,523...165,573,191
Ensembl chr 3:165,520,439...165,572,149 		JBrowse link
G Cdk17 cyclin-dependent kinase 17 increases expression ISO Amiodarone results in increased expression of CDK17 mRNA CTD PMID:19774075 NCBI chr 7:27,683,890...27,765,814
Ensembl chr 7:27,683,890...27,764,910 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C affects expression EXP Amiodarone affects the expression of CDKN2C mRNA CTD PMID:18355885 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Amiodarone affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO
EXP		 Amiodarone results in increased expression of CEBPB mRNA CTD PMID:19774075 PMID:25580480 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Celf6 CUGBP, Elav-like family member 6 increases expression ISO Amiodarone results in increased expression of CELF6 mRNA CTD PMID:19774075 NCBI chr 8:59,975,095...60,006,060
Ensembl chr 8:59,975,088...60,005,041 		JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Amiodarone affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578 		JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Amiodarone results in increased expression of CES1 mRNA CTD PMID:21163907 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Amiodarone affects the expression of CES2 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cfi complement factor I affects expression EXP Amiodarone affects the expression of CFI mRNA CTD PMID:19483382 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression EXP Amiodarone results in decreased expression of CFLAR protein CTD PMID:21224497 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cga glycoprotein hormones, alpha polypeptide increases expression EXP Amiodarone results in increased expression of CGA mRNA CTD PMID:3427795 NCBI chr 5:49,486,915...49,499,192
Ensembl chr 5:49,487,068...49,499,191 		JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Amiodarone results in increased expression of CHAC1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526 		JBrowse link
G Chaf1a chromatin assembly factor 1 subunit A decreases expression EXP Amiodarone results in decreased expression of CHAF1A mRNA CTD PMID:17991464 NCBI chr 9:873,953...900,701
Ensembl chr 9:874,051...900,654 		JBrowse link
G Chat choline O-acetyltransferase decreases expression EXP Amiodarone results in decreased expression of CHAT protein CTD PMID:25659768 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Chga chromogranin A increases expression ISO Amiodarone results in increased expression of CHGA mRNA CTD PMID:19774075 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Amiodarone affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251 		JBrowse link
G Chrnb3 cholinergic receptor nicotinic beta 3 subunit increases expression ISO Amiodarone results in increased expression of CHRNB3 mRNA CTD PMID:19774075 NCBI chr16:64,713,438...64,751,360
Ensembl chr16:64,714,169...64,751,360 		JBrowse link
G Chst5 carbohydrate sulfotransferase 5 increases expression ISO Amiodarone results in increased expression of CHST6 mRNA CTD PMID:19774075 NCBI chr19:39,860,729...39,881,019
Ensembl chr19:39,860,501...39,881,064 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a multiple interactions
increases expression		 ISO 1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA] CTD PMID:28962527 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481 		JBrowse link
G Cidec cell death-inducing DFFA-like effector c increases expression
multiple interactions		 ISO Amiodarone results in increased expression of CIDEC mRNA; Amiodarone results in increased expression of CIDEC protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]		 CTD PMID:28962527 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173 		JBrowse link
G Cimap3 ciliary microtubule associated protein 3 increases expression ISO Amiodarone results in increased expression of CIMAP3 mRNA CTD PMID:19774075 NCBI chr 2:193,475,785...193,493,092
Ensembl chr 2:193,475,782...193,493,139 		JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Amiodarone affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924 		JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Amiodarone affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238 		JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression ISO Amiodarone results in increased expression of CLCN5 mRNA CTD PMID:19774075 NCBI chr  X:15,185,380...15,339,977
Ensembl chr  X:15,185,451...15,334,264 		JBrowse link
G Clcn6 chloride voltage-gated channel 6 increases expression ISO Amiodarone results in increased expression of CLCN6 mRNA CTD PMID:19774075 NCBI chr 5:158,434,299...158,465,174
Ensembl chr 5:158,434,299...158,465,059 		JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Amiodarone affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693 		JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Amiodarone affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO Amiodarone results in increased expression of CLPX mRNA CTD PMID:24535564 NCBI chr 8:65,805,460...65,845,643
Ensembl chr 8:65,805,511...65,845,082 		JBrowse link
G Clvs2 clavesin 2 increases expression ISO Amiodarone results in increased expression of CLVS2 mRNA CTD PMID:19774075 NCBI chr 1:23,735,660...23,842,685
Ensembl chr 1:23,735,272...23,842,692 		JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression
increases expression		 EXP
ISO		 Amiodarone affects the expression of CMBL mRNA
Amiodarone results in increased expression of CMBL mRNA		 CTD PMID:19483382 PMID:24535564 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009 		JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Amiodarone affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830 		JBrowse link
G Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 affects expression EXP Amiodarone affects the expression of CMTM6 mRNA CTD PMID:18355885 NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033 		JBrowse link
G Cmtm7 CKLF-like MARVEL transmembrane domain containing 7 increases expression ISO Amiodarone results in increased expression of CMTM7 mRNA CTD PMID:19774075 NCBI chr 8:114,448,037...114,474,958
Ensembl chr 8:114,448,042...114,474,621 		JBrowse link
G Cmya5 cardiomyopathy associated 5 increases expression ISO Amiodarone results in increased expression of CMYA5 mRNA CTD PMID:19774075 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364 		JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 increases expression ISO Amiodarone results in increased expression of CNIH3 mRNA CTD PMID:19774075 NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121 		JBrowse link
G Cnnm2 cyclin and CBS domain divalent metal cation transport mediator 2 increases expression ISO Amiodarone results in increased expression of CNNM2 mRNA CTD PMID:19774075 NCBI chr 1:245,643,682...245,769,542
Ensembl chr 1:245,643,768...245,763,286 		JBrowse link
G Cnot7 CCR4-NOT transcription complex, subunit 7 increases expression ISO Amiodarone results in increased expression of CNOT7 mRNA CTD PMID:19774075 NCBI chr16:51,775,416...51,794,581
Ensembl chr16:51,775,412...51,794,576 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase increases expression ISO Amiodarone results in increased expression of CNP mRNA CTD PMID:19774075 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Col11a1 collagen type XI alpha 1 chain increases expression ISO Amiodarone results in increased expression of COL11A1 mRNA CTD PMID:19774075 NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression EXP Amiodarone results in increased expression of COL1A1 mRNA CTD PMID:32909452 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col27a1 collagen type XXVII alpha 1 chain increases expression ISO Amiodarone results in increased expression of COL27A1 mRNA CTD PMID:19774075 NCBI chr 5:76,647,302...76,765,989
Ensembl chr 5:76,647,429...76,765,174 		JBrowse link
G Col8a2 collagen type VIII alpha 2 chain increases expression ISO Amiodarone results in increased expression of COL8A2 mRNA CTD PMID:19774075 NCBI chr 5:138,586,201...138,613,627
Ensembl chr 5:138,585,999...138,612,850 		JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Amiodarone affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Amiodarone affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887 		JBrowse link
G Copz2 COPI coat complex subunit zeta 2 increases expression ISO Amiodarone results in increased expression of COPZ2 mRNA CTD PMID:24535564 NCBI chr10:81,832,441...81,845,514
Ensembl chr10:81,832,418...81,845,514 		JBrowse link
G Coq2 coenzyme Q2, polyprenyltransferase increases expression ISO Amiodarone results in increased expression of COQ2 mRNA CTD PMID:24489787 NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891 		JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression
increases expression		 EXP
ISO		 Amiodarone affects the expression of COQ3 mRNA
Amiodarone results in increased expression of COQ3 mRNA		 CTD PMID:19483382 PMID:24489787 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607 		JBrowse link
G Coro2a coronin 2A increases expression ISO Amiodarone results in increased expression of CORO2A mRNA CTD PMID:19774075 NCBI chr 5:60,825,630...60,881,917
Ensembl chr 5:60,828,247...60,859,035 		JBrowse link
G Cort cortistatin affects expression EXP Amiodarone affects the expression of CORT mRNA CTD PMID:31324950 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 increases expression ISO Amiodarone results in increased expression of COX15 mRNA CTD PMID:24489787 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261 		JBrowse link
G Cox17 cytochrome c oxidase copper chaperone COX17 increases expression ISO Amiodarone results in increased expression of COX17 mRNA CTD PMID:24489787 NCBI chr11:62,400,733...62,406,507 JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Amiodarone affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921 		JBrowse link
G Cox6b2 cytochrome c oxidase subunit 6B2 increases expression ISO Amiodarone results in increased expression of COX6B2 mRNA CTD PMID:24535564 NCBI chr 1:69,094,009...69,095,312 JBrowse link
G Cplx2 complexin 2 increases expression ISO Amiodarone results in increased expression of CPLX2 mRNA CTD PMID:19774075 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855 		JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Amiodarone affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465 		JBrowse link
G Cpped1 calcineurin-like phosphoesterase domain containing 1 affects expression EXP Amiodarone affects the expression of CPPED1 mRNA CTD PMID:18355885 NCBI chr10:3,701,522...3,821,050
Ensembl chr10:3,701,459...3,821,054 		JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Amiodarone affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression
affects expression
decreases expression		 ISO
EXP		 Amiodarone results in increased expression of CPT1A mRNA
Amiodarone affects the expression of CPT1A mRNA
Amiodarone results in decreased expression of CPT1A mRNA		 CTD PMID:24489787 PMID:29248575 PMID:32084307 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 increases expression
decreases expression		 ISO
EXP		 Amiodarone results in increased expression of CPT2 mRNA
Amiodarone results in decreased expression of CPT2 mRNA		 CTD PMID:24489787 PMID:30685923 PMID:32084307 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Crb3 crumbs cell polarity complex component 3 increases expression ISO Amiodarone results in increased expression of CRB3 mRNA CTD PMID:19774075 NCBI chr 9:1,898,531...1,903,860
Ensembl chr 9:1,896,623...1,903,859 		JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Amiodarone affects the expression of CREM mRNA CTD PMID:18355885 PMID:19483382 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crot carnitine O-octanoyltransferase decreases expression ISO Amiodarone results in decreased expression of CROT mRNA CTD PMID:27089845 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Crp C-reactive protein multiple interactions ISO Amiodarone inhibits the reaction [CRP protein results in increased expression of CCL2 protein]; Amiodarone inhibits the reaction [CRP protein results in increased expression of TNF protein] CTD PMID:19225199 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Crtc1 CREB regulated transcription coactivator 1 decreases expression EXP Amiodarone results in decreased expression of CRTC1 mRNA CTD PMID:17991464 NCBI chr16:18,988,197...19,046,914
Ensembl chr16:18,988,250...19,043,381 		JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Amiodarone affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Amiodarone affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384 		JBrowse link
G Csrp3 cysteine and glycine rich protein 3 increases expression ISO Amiodarone results in increased expression of CSRP3 mRNA CTD PMID:24535564 NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653 		JBrowse link
G Cst6 cystatin E/M increases expression ISO Amiodarone results in increased expression of CST6 mRNA CTD PMID:19774075 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030 		JBrowse link
G Cst7 cystatin F increases expression ISO Amiodarone results in increased expression of CST7 mRNA CTD PMID:19774075 NCBI chr 3:139,396,830...139,405,557
Ensembl chr 3:139,396,850...139,405,557 		JBrowse link
G Ctc1 CST telomere replication complex component 1 increases expression ISO Amiodarone results in increased expression of CTC1 mRNA CTD PMID:19774075 NCBI chr10:53,714,614...53,735,298
Ensembl chr10:53,714,644...53,735,298 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 increases expression ISO Amiodarone results in increased expression of CTLA4 mRNA CTD PMID:19774075 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Amiodarone affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions ISO ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]; Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of BCL2 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of BAX protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 mRNA]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of CASP3 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of TNF protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of and results in decreased phosphorylation of CTNNB1 protein]] CTD PMID:34434487 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsb cathepsin B affects cleavage ISO Amiodarone affects the cleavage of CTSB protein CTD PMID:25881747 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsd cathepsin D affects cleavage ISO Amiodarone affects the cleavage of CTSD protein CTD PMID:25881747 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Ctsl cathepsin L affects cleavage ISO Amiodarone affects the cleavage of CTSL protein CTD PMID:25881747 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Amiodarone inhibits the reaction [Dexamethasone results in increased expression of CXCL2 mRNA] CTD PMID:25900201 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
increases response to substance
decreases activity		 EXP
ISO		 Amiodarone results in increased expression of CYP1A1 mRNA
Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CYP1A1 protein results in increased susceptibility to Amiodarone
Amiodarone results in decreased activity of CYP1A1 protein		 CTD PMID:19224547 PMID:20362646 PMID:26477383 PMID:32084307 PMID:33814510 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
decreases response to substance
multiple interactions		 ISO Amiodarone results in decreased activity of CYP1A2 protein
CYP1A2 protein results in decreased susceptibility to Amiodarone
[Amiodarone results in decreased activity of CYP1A2 protein] which results in decreased metabolism of Phenacetin		 CTD PMID:16449812 PMID:26477383 PMID:26599973 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases response to substance
decreases activity		 ISO CYP1B1 protein results in decreased susceptibility to Amiodarone
Amiodarone results in decreased activity of CYP1B1 protein		 CTD PMID:26477383 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO Amiodarone results in increased expression of CYP26A1 mRNA CTD PMID:19774075 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression
increases expression		 EXP Amiodarone affects the expression of CYP2A1 mRNA
Amiodarone results in increased expression of CYP2A1 mRNA		 CTD PMID:18355885 PMID:19483382 PMID:32084307 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 affects expression EXP Amiodarone affects the expression of CYP2B15 mRNA CTD PMID:18355885 NCBI chr 1:82,094,188...82,106,492
Ensembl chr 1:82,094,180...82,106,492 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression EXP Amiodarone affects the expression of CYP2B2 mRNA CTD PMID:19483382 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression
decreases response to substance
increases expression		 EXP
ISO		 Amiodarone affects the expression of CYP2B3 mRNA
CYP2B6 protein results in decreased susceptibility to Amiodarone
Amiodarone results in increased expression of CYP2B10 mRNA		 CTD PMID:19483382 PMID:24535564 PMID:26477383 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression
decreases response to substance		 EXP
ISO		 Amiodarone results in decreased expression of CYP2C11 mRNA
CYP2C18 protein results in decreased susceptibility to Amiodarone		 CTD PMID:26477383 PMID:32084307 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases response to substance ISO CYP2C19 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity
increases metabolic processing
multiple interactions
decreases response to substance		 ISO Amiodarone results in decreased activity of CYP2C8 protein
CYP2C8 protein results in increased metabolism of Amiodarone
torsemide inhibits the reaction [Amiodarone results in decreased activity of CYP2C8 protein]
CYP2C8 protein results in decreased susceptibility to Amiodarone		 CTD PMID:15304522 PMID:15716363 PMID:26477383
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Amiodarone affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression
decreases activity
increases expression
multiple interactions		 EXP
ISO		 Amiodarone affects the expression of CYP2D4 mRNA
Amiodarone results in decreased activity of CYP2D6 protein
Amiodarone results in increased expression of CYP2D6 mRNA
CYP2D6 gene polymorphism affects the reaction [Amiodarone results in increased abundance of Metoprolol]		 CTD PMID:15541258 PMID:16449812 PMID:19483382 PMID:19774075 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases response to substance ISO CYP2E1 protein results in decreased susceptibility to Amiodarone CTD PMID:26477383 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Amiodarone affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression
affects expression		 ISO
EXP		 Amiodarone results in increased expression of CYP2J2 mRNA
Amiodarone affects the expression of CYP2J4 mRNA		 CTD PMID:19483382 PMID:19774075 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 increases expression ISO Amiodarone results in increased expression of CYP2R1 mRNA CTD PMID:19774075 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Amiodarone affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563 		JBrowse link
G Cyp2u1 cytochrome P450, family 2, subfamily u, polypeptide 1 decreases expression ISO Amiodarone results in decreased expression of CYP2U1 mRNA CTD PMID:24535564 NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882 		JBrowse link
G Cyp39a1 cytochrome P450, family 39, subfamily a, polypeptide 1 decreases expression ISO Amiodarone results in decreased expression of CYP39A1 mRNA CTD PMID:24535564 NCBI chr 9:17,230,455...17,306,775
Ensembl chr 9:17,230,455...17,306,775 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
decreases ethylation
increases response to substance
increases metabolic processing
multiple interactions
decreases activity
increases degradation		 EXP
ISO		 Amiodarone results in increased expression of CYP3A4 mRNA
CYP3A4 protein results in decreased ethylation of Amiodarone
CYP3A4 protein results in increased susceptibility to Amiodarone
CYP3A4 protein results in increased metabolism of Amiodarone
[Amiodarone co-treated with Benzoic Acid co-treated with cyproconazole co-treated with flusilazole co-treated with enilconazole co-treated with prochloraz co-treated with propiconazole co-treated with tebuconazole] results in increased expression of CYP3A4 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of CXCL8 protein; [Amiodarone co-treated with CYP3A4 protein] results in increased secretion of TNF protein; [CYP3A4 protein results in increased metabolism of Amiodarone] which results in increased abundance of mono-N-desethylamiodarone; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Testosterone]; Amiodarone inhibits the reaction [CYP3A4 protein results in increased oxidation of 7-benzyloxy-4-trifluoromethylcoumarin]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of CXCL8 mRNA]; Ketoconazole inhibits the reaction [[Amiodarone co-treated with CYP3A4 protein] results in increased expression of TNF mRNA]; Metronidazole inhibits the reaction [CYP3A4 protein results in increased metabolism of Amiodarone]
Amiodarone results in decreased activity of CYP3A4 protein
CYP3A4 protein results in increased degradation of Amiodarone		 CTD PMID:7905403 PMID:8445979 PMID:15304522 PMID:15869686 PMID:16449812 More... NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression
increases expression		 EXP Amiodarone affects the expression of CYP3A23-3A1 mRNA
Amiodarone results in increased expression of CYP3A23-3A1 mRNA		 CTD PMID:18355885 PMID:19483382 PMID:32084307 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
Ensembl chr12:9,254,475...9,285,030 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression
decreases response to substance		 EXP
ISO		 Amiodarone affects the expression of CYP3A9 mRNA
CYP3A5 protein results in decreased susceptibility to Amiodarone		 CTD PMID:19483382 PMID:26477383 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Amiodarone results in increased expression of CYP4A1 mRNA CTD PMID:12883083 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464 		JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Amiodarone affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476 		JBrowse link
G Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 affects expression EXP Amiodarone affects the expression of CYP4F2 mRNA CTD PMID:18355885 NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506 		JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Amiodarone affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression
increases expression		 EXP Amiodarone results in decreased expression of CYP7A1 mRNA
Amiodarone results in increased expression of CYP7A1 mRNA		 CTD PMID:19224547 PMID:22291062 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of CYP7B1 mRNA CTD PMID:24535564 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698 		JBrowse link
G Dact1 dishevelled-binding antagonist of beta-catenin 1 decreases expression ISO Amiodarone results in decreased expression of DACT1 mRNA CTD PMID:24535564 NCBI chr 6:89,790,676...89,818,254
Ensembl chr 6:89,790,644...89,817,906 		JBrowse link
G Dapk2 death-associated protein kinase 2 increases expression ISO Amiodarone results in increased expression of DAPK2 mRNA CTD PMID:19774075 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567 		JBrowse link
G Dbi diazepam binding inhibitor affects expression EXP Amiodarone affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Dbn1 drebrin 1 increases expression ISO Amiodarone results in increased expression of DBN1 mRNA CTD PMID:19774075 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dbndd1 dysbindin domain containing 1 increases expression ISO Amiodarone results in increased expression of DBNDD1 mRNA CTD PMID:19774075 NCBI chr19:51,539,154...51,548,441
Ensembl chr19:51,539,148...51,548,444 		JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Amiodarone affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669 		JBrowse link
G Dcaf8 DDB1 and CUL4 associated factor 8 affects expression EXP Amiodarone affects the expression of DCAF8 mRNA CTD PMID:18355885 NCBI chr13:84,609,838...84,667,025
Ensembl chr13:84,610,248...84,669,726 		JBrowse link
G Dcst2 DC-STAMP domain containing 2 increases expression ISO Amiodarone results in increased expression of DCST2 mRNA CTD PMID:19774075 NCBI chr 2:174,781,806...174,795,834
Ensembl chr 2:174,781,902...174,795,832 		JBrowse link
G Dctn1 dynactin subunit 1 increases expression ISO Amiodarone results in increased expression of DCTN1 mRNA CTD PMID:19774075 NCBI chr 4:115,671,024...115,703,824
Ensembl chr 4:115,661,638...115,703,815 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Amiodarone affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:106,006,404...106,008,293 JBrowse link
G Ddc dopa decarboxylase increases expression ISO Amiodarone results in increased expression of DDC mRNA CTD PMID:24489787 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
decreases response to substance		 ISO [Amiodarone results in increased expression of DDIT3 mRNA] which results in increased expression of TNFRSF10B mRNA; [Amiodarone results in increased expression of DDIT3 protein] which results in increased expression of TNFRSF10B protein; Amiodarone results in increased expression of DDIT3 mRNA; Amiodarone results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DDIT3 protein]; DDIT3 mutant form inhibits the reaction [Amiodarone results in increased expression of TNFRSF10B]; Egtazic Acid inhibits the reaction [Amiodarone results in increased expression of DDIT3]
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DDIT3 mRNA]; Amiodarone results in increased expression of and affects the localization of DDIT3 protein; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEA mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of CIDEC protein]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased splicing of XBP1 mRNA]
DDIT3 gene mutant form results in decreased susceptibility to Amiodarone		 CTD PMID:19774075 PMID:21292685 PMID:25295624 PMID:28962527 PMID:32651653 More... NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Amiodarone results in increased expression of DDIT4 mRNA CTD PMID:19774075 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddx17 DEAD-box helicase 17 increases expression ISO Amiodarone results in increased expression of DDX17 mRNA CTD PMID:19774075 NCBI chr 7:111,091,127...111,109,353
Ensembl chr 7:111,089,445...111,109,193 		JBrowse link
G Ddx31 DEAD-box helicase 31 increases expression ISO Amiodarone results in increased expression of DDX31 mRNA CTD PMID:19774075 NCBI chr 3:12,172,829...12,238,392
Ensembl chr 3:12,172,836...12,238,873 		JBrowse link
G Ddx39a DExD-box helicase 39A increases expression ISO Amiodarone results in increased expression of DDX39A mRNA CTD PMID:19774075 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954 		JBrowse link
G Ddx49 DEAD-box helicase 49 increases expression ISO Amiodarone results in increased expression of DDX49 mRNA CTD PMID:19774075 NCBI chr16:19,125,388...19,133,042
Ensembl chr16:19,125,384...19,133,616 		JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Amiodarone affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018 		JBrowse link
G Dedd death effector domain-containing increases expression ISO Amiodarone results in increased expression of DEDD mRNA CTD PMID:19774075 NCBI chr13:83,755,874...83,769,982
Ensembl chr13:83,756,108...83,769,332 		JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO Amiodarone results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Deptor DEP domain containing MTOR-interacting protein increases expression ISO Amiodarone results in increased expression of DEPTOR mRNA CTD PMID:19774075 NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773 		JBrowse link
G Dexi Dexi homolog affects expression EXP Amiodarone affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738 		JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression
increases expression		 EXP
ISO		 Amiodarone affects the expression of DGAT1 mRNA
Amiodarone results in increased expression of DGAT1 mRNA		 CTD PMID:19483382 PMID:32651653 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299 		JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 decreases expression ISO Amiodarone results in decreased expression of DGAT2 mRNA CTD PMID:28962527 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Amiodarone affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression EXP Amiodarone results in increased expression of DHCR7 mRNA CTD PMID:22291062 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 increases expression ISO Amiodarone results in increased expression of DHRS2 mRNA CTD PMID:19774075 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Amiodarone affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127 		JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Amiodarone affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076 		JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Amiodarone affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948 		JBrowse link
G Dhx57 DExH-box helicase 57 increases expression ISO Amiodarone results in increased expression of DHX57 mRNA CTD PMID:19774075 NCBI chr 6:14,725,305...14,776,321
Ensembl chr 6:14,725,303...14,776,321 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity EXP
ISO		 Amiodarone results in decreased activity of DIO1 protein CTD PMID:12538616 PMID:16131326 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 increases expression ISO Amiodarone results in increased expression of DLG4 mRNA CTD PMID:19774075 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Dlk2 delta like non-canonical Notch ligand 2 increases expression ISO Amiodarone results in increased expression of DLK2 mRNA CTD PMID:19774075 NCBI chr 9:14,677,102...14,681,584
Ensembl chr 9:14,676,562...14,681,594 		JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Amiodarone affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933 		JBrowse link
G Dnaaf3 dynein, axonemal, assembly factor 3 increases expression ISO Amiodarone results in increased expression of DNAAF3 mRNA CTD PMID:19774075 NCBI chr 1:69,291,300...69,299,365
Ensembl chr 1:69,291,454...69,299,344 		JBrowse link
G Dnah7 dynein, axonemal, heavy chain 7 increases expression ISO Amiodarone results in increased expression of DNAH7 mRNA CTD PMID:19774075 NCBI chr 9:54,960,235...55,266,529
Ensembl chr 9:54,960,440...55,262,297 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 decreases expression ISO Amiodarone results in decreased expression of DNAJB11 mRNA CTD PMID:24535564 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407 		JBrowse link
G Dnajb12 DnaJ heat shock protein family (Hsp40) member B12 increases expression ISO Amiodarone results in increased expression of DNAJB12 mRNA CTD PMID:19774075 NCBI chr20:27,828,216...27,846,428
Ensembl chr20:27,828,235...27,846,427 		JBrowse link
G Dnajb7 DnaJ heat shock protein family (Hsp40) member B7 increases expression ISO Amiodarone results in increased expression of DNAJB7 mRNA CTD PMID:19774075 NCBI chr 7:112,932,736...112,934,050
Ensembl chr 7:112,932,616...112,945,537 		JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression
multiple interactions		 ISO Amiodarone results in increased expression of DNAJB9 mRNA
Amiodarone results in increased expression of DNAJB9 mRNA; Amiodarone results in increased expression of DNAJB9 protein
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; 4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]; DDIT3 gene mutant form inhibits the reaction [Amiodarone results in increased expression of DNAJB9 mRNA]		 CTD PMID:19774075 PMID:28962527 PMID:34259586 PMID:36586010 NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression
multiple interactions
increases expression		 EXP
ISO		 Amiodarone affects the expression of DNAJC3 mRNA
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of DNAJC3 mRNA]		 CTD PMID:19483382 PMID:28962527 PMID:34259586 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Dnase1 deoxyribonuclease 1 increases expression ISO Amiodarone results in increased expression of DNASE1 mRNA CTD PMID:19774075 NCBI chr10:11,498,930...11,505,151
Ensembl chr10:11,498,931...11,501,869 		JBrowse link
G Dock5 dedicator of cytokinesis 5 increases expression ISO Amiodarone results in increased expression of DOCK5 mRNA CTD PMID:19774075 NCBI chr15:41,979,728...42,158,733
Ensembl chr15:41,979,729...42,158,649 		JBrowse link
G Dpm2 dolichyl-phosphate mannosyltransferase subunit 2, regulatory increases expression ISO Amiodarone results in increased expression of DPM2 mRNA CTD PMID:19774075 NCBI chr 3:15,855,952...15,858,867
Ensembl chr 3:15,856,182...15,869,165
Ensembl chr 3:15,856,182...15,869,165 		JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Amiodarone affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901 		JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Amiodarone affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982 		JBrowse link
G Drc7 dynein regulatory complex subunit 7 increases expression ISO Amiodarone results in increased expression of DRC7 mRNA CTD PMID:19774075 NCBI chr19:9,943,452...9,961,266
Ensembl chr19:9,943,456...9,961,163 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Amiodarone results in increased expression of DUSP1 mRNA CTD PMID:19774075 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Amiodarone results in increased expression of DUSP10 mRNA CTD PMID:19774075 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Dut deoxyuridine triphosphatase increases expression ISO Amiodarone results in increased expression of DUT mRNA CTD PMID:19774075 NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771 		JBrowse link
G Eaf2 ELL associated factor 2 increases expression ISO Amiodarone results in increased expression of EAF2 mRNA CTD PMID:19774075 NCBI chr11:63,960,200...64,004,610
Ensembl chr11:63,960,200...64,004,610 		JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Amiodarone affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836 		JBrowse link
G Ebp EBP, cholestenol delta-isomerase increases expression EXP Amiodarone results in increased expression of EBP mRNA CTD PMID:22291062 NCBI chr  X:14,299,427...14,305,826
Ensembl chr  X:14,299,448...14,305,826 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression ISO Amiodarone results in increased expression of ECH1 mRNA CTD PMID:24535564 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795 		JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Amiodarone affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884 		JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Amiodarone affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061 		JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Amiodarone affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781 		JBrowse link
G Ecpas Ecm29 proteasome adaptor and scaffold decreases expression EXP Amiodarone results in decreased expression of ECPAS mRNA CTD PMID:17991464 NCBI chr 5:73,601,745...73,714,026
Ensembl chr 5:73,604,533...73,713,860 		JBrowse link
G Eed embryonic ectoderm development increases expression ISO Amiodarone results in increased expression of EED mRNA CTD PMID:19774075 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Amiodarone affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382 		JBrowse link
G Eepd1 endonuclease/exonuclease/phosphatase family domain containing 1 increases expression ISO Amiodarone results in increased expression of EEPD1 mRNA CTD PMID:19774075 NCBI chr 8:23,957,258...24,064,343
Ensembl chr 8:23,957,255...24,064,340 		JBrowse link
G Efcab5 EF-hand calcium binding domain 5 increases expression ISO Amiodarone results in increased expression of EFCAB5 mRNA CTD PMID:19774075 NCBI chr10:61,926,419...62,042,745
Ensembl chr10:61,926,953...62,042,749 		JBrowse link
G Efcc1 EF-hand and coiled-coil domain containing 1 increases expression ISO Amiodarone results in increased expression of EFCC1 mRNA CTD PMID:19774075 NCBI chr 4:120,188,202...120,223,464
Ensembl chr 4:120,188,470...120,217,516 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]] CTD PMID:26515726 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfl6 EGF-like-domain, multiple 6 increases expression ISO Amiodarone results in increased expression of EGFL6 mRNA CTD PMID:19774075 NCBI chr  X:27,884,087...27,942,044
Ensembl chr  X:27,884,125...27,942,044 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression
multiple interactions
decreases phosphorylation		 ISO Amiodarone results in decreased expression of EGFR mRNA
Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]; RTKI cpd promotes the reaction [Amiodarone inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein]]
Amiodarone affects the reaction [VCAN protein alternative form affects the phosphorylation of EGFR protein]
Amiodarone results in decreased phosphorylation of EGFR protein		 CTD PMID:24535564 PMID:26515726 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Amiodarone results in increased expression of EGR1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 increases expression ISO Amiodarone results in increased expression of EGR2 mRNA CTD PMID:19774075 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression
increases expression
decreases expression		 EXP
ISO		 Amiodarone affects the expression of EHHADH mRNA
Amiodarone results in increased expression of EHHADH mRNA
Amiodarone results in decreased expression of EHHADH mRNA		 CTD PMID:15265979 PMID:19483382 PMID:24489787 PMID:24535564 PMID:27089845 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Ehmt1 euchromatic histone lysine methyltransferase 1 increases expression ISO Amiodarone results in increased expression of EHMT1 mRNA CTD PMID:19774075 NCBI chr 3:7,580,680...7,729,046
Ensembl chr 3:7,580,683...7,729,007 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO Amiodarone results in increased phosphorylation of EIF2A protein CTD PMID:21292685 PMID:28962527 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression ISO Amiodarone results in increased expression of EIF2AK3 mRNA CTD PMID:19774075 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions		 ISO Amiodarone results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased phosphorylation of EIF2S1 protein]		 CTD PMID:25295624 PMID:32651653 PMID:34259586 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Amiodarone affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781 		JBrowse link
G Eif4b eukaryotic translation initiation factor 4B affects expression EXP Amiodarone affects the expression of EIF4B mRNA CTD PMID:18355885 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein] CTD PMID:19771169 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions
affects expression
decreases phosphorylation		 ISO
EXP		 Amiodarone inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein]; Amiodarone promotes the reaction [EIF4E protein binds to EIF4EBP1 protein]
Amiodarone affects the expression of EIF4EBP1 mRNA
Amiodarone results in decreased phosphorylation of EIF4EBP1 protein		 CTD PMID:19483382 PMID:19771169 PMID:23912912 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Amiodarone affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 increases expression ISO Amiodarone results in increased expression of EIF5 mRNA CTD PMID:19774075 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Elmo3 engulfment and cell motility 3 increases expression ISO Amiodarone results in increased expression of ELMO3 mRNA CTD PMID:19774075 NCBI chr19:33,181,952...33,186,399
Ensembl chr19:33,182,036...33,186,410 		JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 increases expression
decreases expression		 ISO Amiodarone results in increased expression of ELOVL6 mRNA
Amiodarone results in decreased expression of ELOVL6 mRNA; Amiodarone results in decreased expression of ELOVL6 protein		 CTD PMID:24489787 PMID:29248575 PMID:34259586 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 increases expression ISO Amiodarone results in increased expression of ELP1 mRNA CTD PMID:19774075 NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762 		JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Amiodarone affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713 		JBrowse link
G Enho energy homeostasis associated decreases expression ISO Amiodarone results in decreased expression of ENHO mRNA CTD PMID:24535564 NCBI chr 5:56,800,980...56,802,777
Ensembl chr 5:56,800,980...56,802,777 		JBrowse link
G Eno1 enolase 1 affects expression EXP Amiodarone affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Amiodarone affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947 		JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Amiodarone affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715 		JBrowse link
G Enpp7 ectonucleotide pyrophosphatase/phosphodiesterase 7 increases expression ISO Amiodarone results in increased expression of ENPP7 mRNA CTD PMID:19774075 NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589 		JBrowse link
G Epc1 enhancer of polycomb homolog 1 increases expression ISO Amiodarone results in increased expression of EPC1 mRNA CTD PMID:19774075 NCBI chr17:54,503,358...54,594,444
Ensembl chr17:54,503,358...54,594,425 		JBrowse link
G Epc2 enhancer of polycomb homolog 2 increases expression ISO Amiodarone results in increased expression of EPC2 mRNA CTD PMID:19774075 NCBI chr 3:33,867,219...33,967,908
Ensembl chr 3:33,867,219...33,967,150 		JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Amiodarone affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127 		JBrowse link
G Ephx1 epoxide hydrolase 1 affects expression EXP Amiodarone affects the expression of EPHX1 mRNA CTD PMID:18355885 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Eri2 ERI1 exoribonuclease family member 2 increases expression ISO Amiodarone results in increased expression of ERI2 mRNA CTD PMID:19774075 NCBI chr 1:174,140,831...174,168,757
Ensembl chr 1:174,141,993...174,168,665 		JBrowse link
G Ermn ermin increases expression ISO Amiodarone results in increased expression of ERMN mRNA CTD PMID:19774075 NCBI chr 3:42,628,160...42,633,816
Ensembl chr 3:42,626,309...42,633,744 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 increases phosphorylation ISO Amiodarone results in increased phosphorylation of ERN1 protein CTD PMID:28962527 PMID:32651653 PMID:34259586 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Ero1b endoplasmic reticulum oxidoreductase 1 beta decreases expression ISO Amiodarone results in decreased expression of ERO1B mRNA CTD PMID:24535564 NCBI chr17:85,861,086...86,003,244
Ensembl chr17:85,929,618...86,003,398 		JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Amiodarone affects the expression of ERP29 mRNA CTD PMID:18355885 PMID:19483382 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376 		JBrowse link
G Esd esterase D affects expression EXP Amiodarone affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144 		JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Amiodarone affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068 		JBrowse link
G Etfdh electron transfer flavoprotein dehydrogenase increases expression ISO Amiodarone results in increased expression of ETFDH mRNA CTD PMID:24489787 NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745 		JBrowse link
G Exo1 exonuclease 1 increases expression ISO Amiodarone results in increased expression of EXO1 mRNA CTD PMID:19774075 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G F11 coagulation factor XI decreases expression ISO Amiodarone results in decreased expression of F11 mRNA CTD PMID:24535564 NCBI chr16:46,987,988...47,009,015
Ensembl chr16:46,986,107...47,008,437 		JBrowse link
G F2 coagulation factor II, thrombin multiple interactions ISO Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein] CTD PMID:18974383 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases activity		 ISO Amiodarone inhibits the reaction [F2 protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of and results in increased activity of F3 protein]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 mRNA]; Amiodarone inhibits the reaction [TNF protein results in increased expression of F3 protein]
Amiodarone results in decreased activity of F3 protein		 CTD PMID:18974383 PMID:23305835 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Amiodarone affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression
decreases expression		 ISO Amiodarone results in increased expression of FABP1 mRNA
Amiodarone results in decreased expression of FABP1 mRNA		 CTD PMID:15342952 PMID:17567588 PMID:28962527 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Amiodarone results in increased expression of FABP4 mRNA CTD PMID:34259586 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Fads1 fatty acid desaturase 1 increases expression EXP Amiodarone results in increased expression of FADS1 mRNA CTD PMID:19224547 PMID:22291062 NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734 		JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions
increases expression
affects expression		 ISO
EXP		 [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Amiodarone results in increased expression of FADS2 mRNA]; FADS2 protein affects the reaction [Amiodarone results in increased uptake of 1-acyl-2-(12-((7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)dodecanoyl)phosphatidylcholine]
Amiodarone affects the expression of FADS2 mRNA		 CTD PMID:19483382 PMID:21123845 PMID:29248575 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fam81a family with sequence similarity 81, member A increases expression ISO Amiodarone results in increased expression of FAM81A mRNA CTD PMID:19774075 NCBI chr 8:70,762,852...70,821,898
Ensembl chr 8:70,763,614...70,821,875 		JBrowse link
G Fam89a family with sequence similarity 89, member A increases expression ISO Amiodarone results in increased expression of FAM89A mRNA CTD PMID:19774075 NCBI chr19:52,710,002...52,722,630
Ensembl chr19:52,710,019...52,722,631 		JBrowse link
G Fanca FA complementation group A increases expression ISO Amiodarone results in increased expression of FANCA mRNA CTD PMID:19774075 NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527 		JBrowse link
G Farp2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 increases expression ISO Amiodarone results in increased expression of FARP2 mRNA CTD PMID:19774075 NCBI chr 9:94,053,650...94,161,982
Ensembl chr 9:94,053,726...94,162,212 		JBrowse link
G Fasn fatty acid synthase increases expression
affects expression
decreases expression		 ISO
EXP		 Amiodarone results in increased expression of FASN mRNA
Amiodarone affects the expression of FASN mRNA
Amiodarone results in decreased expression of FASN mRNA; Amiodarone results in decreased expression of FASN protein		 CTD PMID:22291062 PMID:24489787 PMID:29248575 PMID:32084307 PMID:34259586 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Amiodarone affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbxo16 F-box protein 16 increases expression ISO Amiodarone results in increased expression of FBXO16 mRNA CTD PMID:19774075 NCBI chr15:39,492,268...39,541,493
Ensembl chr15:39,492,377...39,541,480 		JBrowse link
G Fbxo32 F-box protein 32 increases expression ISO Amiodarone results in increased expression of FBXO32 mRNA CTD PMID:19774075 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Fcgr2b Fc gamma receptor 2B increases expression EXP Amiodarone results in increased expression of FCGR2B mRNA CTD PMID:25580480 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Fcrl2 Fc receptor-like 2 increases expression ISO Amiodarone results in increased expression of FCRL2 mRNA CTD PMID:19774075 NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression
increases expression		 EXP Amiodarone affects the expression of FDFT1 mRNA
Amiodarone results in increased expression of FDFT1 mRNA		 CTD PMID:19483382 PMID:22291062 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fdps farnesyl diphosphate synthase affects expression
increases expression		 EXP Amiodarone affects the expression of FDPS mRNA
Amiodarone results in increased expression of FDPS mRNA		 CTD PMID:19483382 PMID:22291062 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Amiodarone affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849 		JBrowse link
G Ffar3 free fatty acid receptor 3 increases expression ISO Amiodarone results in increased expression of FFAR3 mRNA CTD PMID:19774075 NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849 		JBrowse link
G Fgd4 FYVE, RhoGEF and PH domain containing 4 increases expression ISO Amiodarone results in increased expression of FGD4 mRNA CTD PMID:19774075 NCBI chr11:84,399,989...84,551,013
Ensembl chr11:84,399,816...84,546,972 		JBrowse link
G Fgd5 FYVE, RhoGEF and PH domain containing 5 increases expression ISO Amiodarone results in increased expression of FGD5 mRNA CTD PMID:19774075 NCBI chr 4:124,497,061...124,594,564
Ensembl chr 4:124,497,068...124,594,563 		JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression ISO Amiodarone results in increased expression of FGF21 mRNA CTD PMID:24489787 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression EXP Amiodarone results in increased expression of FGF7 protein CTD PMID:32909452 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fgfr1op2 FGFR1 oncogene partner 2 increases expression ISO Amiodarone results in increased expression of FGFR1OP2 mRNA CTD PMID:19774075 NCBI chr 4:179,491,602...179,512,630
Ensembl chr 4:179,491,599...179,512,630 		JBrowse link
G Fibcd1 fibrinogen C domain containing 1 increases expression ISO Amiodarone results in increased expression of FIBCD1 mRNA CTD PMID:19774075 NCBI chr 3:15,092,682...15,126,371
Ensembl chr 3:15,092,681...15,126,399 		JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Amiodarone results in increased expression of FKBP10 mRNA CTD PMID:19774075 NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330 		JBrowse link
G Fkbp11 FKBP prolyl isomerase 11 decreases expression ISO Amiodarone results in decreased expression of FKBP11 mRNA CTD PMID:24535564 NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303 		JBrowse link
G Flcn folliculin increases expression ISO Amiodarone results in increased expression of FLCN mRNA CTD PMID:19774075 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Amiodarone affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Amiodarone results in increased expression of FNDC4 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO Amiodarone results in increased expression of FOS mRNA
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]		 CTD PMID:17214612 PMID:19774075 PMID:36586010 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO Amiodarone results in increased expression of FOSB mRNA CTD PMID:19774075 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Foxa1 forkhead box A1 decreases expression ISO Amiodarone results in decreased expression of FOXA1 mRNA CTD PMID:27089845 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188 		JBrowse link
G Foxa3 forkhead box A3 decreases expression EXP
ISO		 Amiodarone results in decreased expression of FOXA3 mRNA CTD PMID:17991464 PMID:24535564 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155 		JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Amiodarone results in increased expression of FOXP3 mRNA CTD PMID:19774075 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 increases expression ISO Amiodarone results in increased expression of FRAS1 mRNA CTD PMID:19774075 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726 		JBrowse link
G Frmd3 FERM domain containing 3 increases expression ISO Amiodarone results in increased expression of FRMD3 mRNA CTD PMID:19774075 NCBI chr 5:87,764,755...88,031,091
Ensembl chr 5:87,764,604...88,031,091 		JBrowse link
G Frmd5 FERM domain containing 5 increases expression ISO Amiodarone results in increased expression of FRMD5 mRNA CTD PMID:19774075 NCBI chr 3:108,492,099...108,763,715
Ensembl chr 3:108,474,562...108,763,498 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Amiodarone results in increased expression of FTL mRNA CTD PMID:36586010 NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G Fundc2 FUN14 domain containing 2 increases expression ISO Amiodarone results in increased expression of FUNDC2 mRNA CTD PMID:19774075 NCBI chr18:128,473...138,232
Ensembl chr18:132,248...138,345 		JBrowse link
G Fut4 fucosyltransferase 4 decreases expression EXP Amiodarone results in decreased expression of FUT4 mRNA CTD PMID:17991464 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682 		JBrowse link
G Fuz fuzzy planar cell polarity protein increases expression ISO Amiodarone results in increased expression of FUZ mRNA CTD PMID:19774075 NCBI chr 1:95,379,542...95,384,532
Ensembl chr 1:95,379,587...95,384,530 		JBrowse link
G Fxyd1 FXYD domain-containing ion transport regulator 1 increases expression ISO Amiodarone results in increased expression of FXYD1 mRNA CTD PMID:19774075 NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression EXP
ISO		 Amiodarone results in increased expression of G6PDX mRNA
Amiodarone results in increased expression of G6PD mRNA		 CTD PMID:19224547 PMID:19774075 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Amiodarone results in increased expression of GADD45A mRNA CTD PMID:19774075 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Amiodarone results in increased expression of GADD45G mRNA CTD PMID:19774075 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610 		JBrowse link
G Gal galanin and GMAP prepropeptide increases expression EXP Amiodarone results in increased expression of GAL mRNA CTD PMID:25580480 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gal3st3 galactose-3-O-sulfotransferase 3 increases expression ISO Amiodarone results in increased expression of GAL3ST3 mRNA CTD PMID:19774075 NCBI chr 1:202,593,635...202,603,446
Ensembl chr 1:202,593,692...202,603,445 		JBrowse link
G Galnt17 polypeptide N-acetylgalactosaminyltransferase 17 increases expression ISO Amiodarone results in increased expression of GALNT17 mRNA CTD PMID:19774075 NCBI chr12:25,323,230...25,781,897
Ensembl chr12:25,322,701...25,781,290 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Amiodarone affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Amiodarone affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gata2 GATA binding protein 2 decreases expression EXP Amiodarone results in decreased expression of GATA2 mRNA CTD PMID:17991464 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gatb glutamyl-tRNA amidotransferase subunit B increases expression ISO Amiodarone results in increased expression of GATB mRNA CTD PMID:24535564 NCBI chr 2:170,930,547...171,017,133
Ensembl chr 2:170,930,542...171,016,695 		JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Amiodarone affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210 		JBrowse link
G Gbp2 guanylate binding protein 2 increases expression ISO Amiodarone results in increased expression of GBP2 mRNA CTD PMID:19774075 NCBI chr 2:231,332,488...231,348,573
Ensembl chr 2:231,332,284...231,348,571 		JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Amiodarone affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080 		JBrowse link
G Gckr glucokinase regulator affects expression EXP Amiodarone affects the expression of GCKR mRNA CTD PMID:18355885 NCBI chr 6:25,044,592...25,075,834
Ensembl chr 6:25,045,100...25,075,654 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Amiodarone results in increased expression of GCLM mRNA CTD PMID:36586010 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Amiodarone results in increased expression of GDF15 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdf5 growth differentiation factor 5 increases expression ISO Amiodarone results in increased expression of GDF5 mRNA CTD PMID:19774075 NCBI chr 3:144,454,316...144,458,508
Ensembl chr 3:144,454,338...144,458,612 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Amiodarone results in increased expression of GDPD3 mRNA CTD PMID:17175557 PMID:17567588 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle increases expression ISO Amiodarone results in increased expression of GEM mRNA CTD PMID:19774075 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP Amiodarone results in increased expression of GFAP mRNA CTD PMID:22954530 PMID:25659768 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gfod1 Gfo/Idh/MocA-like oxidoreductase domain containing 1 increases expression ISO Amiodarone results in increased expression of GFOD1 mRNA CTD PMID:19774075 NCBI chr17:21,400,142...21,504,972
Ensembl chr17:21,399,479...21,499,938 		JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Amiodarone affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787 		JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA] CTD PMID:2910914 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Gins1 GINS complex subunit 1 increases expression ISO Amiodarone results in increased expression of GINS1 mRNA CTD PMID:19774075 NCBI chr 3:139,724,513...139,745,930
Ensembl chr 3:139,724,490...139,745,936 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO Amiodarone results in decreased expression of GJA1 mRNA CTD PMID:15520326 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gja5 gap junction protein, alpha 5 increases expression ISO Amiodarone results in increased expression of GJA5 mRNA CTD PMID:19774075 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Amiodarone affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Gjd3 gap junction protein, delta 3 increases expression ISO Amiodarone results in increased expression of GJD3 mRNA CTD PMID:19774075 NCBI chr10:83,933,694...83,935,759
Ensembl chr10:83,934,135...83,934,971 		JBrowse link
G Gk5 glycerol kinase 5 increases expression ISO Amiodarone results in increased expression of GK5 mRNA CTD PMID:19774075 NCBI chr 8:96,682,469...96,751,407
Ensembl chr 8:96,682,470...96,749,166 		JBrowse link
G Gkap1 G kinase anchoring protein 1 increases expression ISO Amiodarone results in increased expression of GKAP1 mRNA CTD PMID:19774075 NCBI chr17:6,383,963...6,423,684
Ensembl chr17:6,383,963...6,423,679 		JBrowse link
G Gls2 glutaminase 2 affects expression EXP Amiodarone affects the expression of GLS2 mRNA CTD PMID:18355885 NCBI chr 7:617,252...633,424
Ensembl chr 7:617,288...633,426 		JBrowse link
G Glud1 glutamate dehydrogenase 1 increases expression EXP Amiodarone results in increased expression of GLUD1 protein CTD PMID:16538043 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Gnas GNAS complex locus increases expression ISO Amiodarone results in increased expression of GNAS mRNA CTD PMID:19774075 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnl1 G protein nucleolar 1 decreases expression EXP Amiodarone results in decreased expression of GNL1 mRNA CTD PMID:17991464 NCBI chr20:2,783,130...2,792,115
Ensembl chr20:2,778,985...2,792,115 		JBrowse link
G Gnpat glyceronephosphate O-acyltransferase increases expression EXP Amiodarone results in increased expression of GNPAT mRNA CTD PMID:22291062 NCBI chr19:52,822,326...52,848,872
Ensembl chr19:52,822,319...52,852,361 		JBrowse link
G Gon4l gon-4 like increases expression ISO Amiodarone results in increased expression of GON4L mRNA CTD PMID:19774075 NCBI chr 2:174,233,461...174,306,636
Ensembl chr 2:174,233,461...174,306,634 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression EXP Amiodarone affects the expression of GOT2 mRNA CTD PMID:18355885 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Amiodarone results in increased expression of GPAM mRNA CTD PMID:19224547 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Amiodarone results in increased expression of GPAT3 mRNA CTD PMID:24535564 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490 		JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Amiodarone affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939 		JBrowse link
G Gprc5c G protein-coupled receptor, class C, group 5, member C increases expression ISO Amiodarone results in increased expression of GPRC5C mRNA CTD PMID:19774075 NCBI chr10:99,886,900...99,908,928
Ensembl chr10:99,887,077...99,908,926 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression
increases activity
multiple interactions		 ISO
EXP		 Amiodarone results in increased expression of GPT protein
Amiodarone results in increased activity of GPT protein
1-aminobenzotriazole promotes the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]; [Dexamethasone results in increased susceptibility to Amiodarone] which results in increased expression of GPT protein; Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]; gadolinium chloride inhibits the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]		 CTD PMID:8522712 PMID:22291062 PMID:24685772 PMID:25900201 PMID:32084307 More... NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Amiodarone results in increased expression of GPT2 mRNA CTD PMID:24489787 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression
decreases expression
multiple interactions		 EXP
ISO		 Amiodarone affects the expression of GPX1 mRNA
Amiodarone results in decreased expression of GPX1 mRNA
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of GPX1 mRNA]]		 CTD PMID:19483382 PMID:34434487 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Amiodarone affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Grb14 growth factor receptor bound protein 14 affects expression EXP Amiodarone affects the expression of GRB14 mRNA CTD PMID:18355885 NCBI chr 3:49,568,210...49,683,805
Ensembl chr 3:49,568,210...49,683,889 		JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Amiodarone affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases expression ISO Amiodarone results in increased expression of GRM2 mRNA CTD PMID:19774075 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Amiodarone affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation ISO Amiodarone results in decreased phosphorylation of GSK3B protein CTD PMID:26515726 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsn gelsolin increases expression EXP Amiodarone results in increased expression of GSN mRNA CTD PMID:17991464 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression ISO Amiodarone results in increased expression of GSTA2 mRNA CTD PMID:36586010 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 increases expression ISO Amiodarone results in increased expression of GSTO2 mRNA CTD PMID:19774075 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Amiodarone affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression ISO Amiodarone results in increased expression of GSTZ1 mRNA CTD PMID:19774075 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Amiodarone affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939 		JBrowse link
G Gucy1a2 guanylate cyclase 1 soluble subunit alpha 2 increases expression ISO Amiodarone results in increased expression of GUCY1A2 mRNA CTD PMID:19774075 NCBI chr 8:500,212...900,201
Ensembl chr 8:500,212...889,203 		JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 increases expression ISO Amiodarone results in increased expression of GUCY1B1 mRNA CTD PMID:19774075 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916 		JBrowse link
G Gzma granzyme A affects expression EXP Amiodarone affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G H2aj H2A.J histone increases expression ISO Amiodarone results in increased expression of H2AJ mRNA CTD PMID:19774075 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006 		JBrowse link
G H2bc6 H2B clustered histone 6 increases expression ISO Amiodarone results in increased expression of H2BC6 mRNA CTD PMID:19774075 NCBI chr17:41,520,775...41,521,238 JBrowse link
G H3f3b H3.3 histone B affects expression EXP Amiodarone affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:101,256,484...101,258,716
Ensembl chr10:101,256,480...101,258,709 		JBrowse link
G Hal histidine ammonia lyase affects expression EXP Amiodarone affects the expression of HAL mRNA CTD PMID:18355885 PMID:19483382 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701 		JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Amiodarone affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Amiodarone affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Amiodarone affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 increases expression ISO Amiodarone results in increased expression of HCN1 mRNA CTD PMID:19774075 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hcn2 hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 decreases expression EXP Amiodarone results in decreased expression of HCN2 mRNA CTD PMID:17711693 NCBI chr 7:9,969,801...9,988,839
Ensembl chr 7:9,970,368...9,988,841 		JBrowse link
G Hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 decreases expression EXP Amiodarone results in decreased expression of HCN4 mRNA CTD PMID:17711693 NCBI chr 8:59,222,206...59,259,626
Ensembl chr 8:59,221,653...59,259,639 		JBrowse link
G Hdc histidine decarboxylase affects expression EXP Amiodarone affects the expression of HDC mRNA CTD PMID:19483382 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341 		JBrowse link
G Hdx highly divergent homeobox increases expression ISO Amiodarone results in increased expression of HDX mRNA CTD PMID:19774075 NCBI chr  X:76,552,539...76,697,177
Ensembl chr  X:76,560,665...76,869,972 		JBrowse link
G Helb DNA helicase B increases expression ISO Amiodarone results in increased expression of HELB mRNA CTD PMID:19774075 NCBI chr 7:55,588,510...55,615,979
Ensembl chr 7:55,588,798...55,615,585 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Amiodarone results in increased expression of HERPUD1 mRNA CTD PMID:19774075 PMID:36586010 NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 decreases expression EXP Amiodarone results in decreased expression of HES6 mRNA CTD PMID:17991464 NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559 		JBrowse link
G Hexa hexosaminidase subunit alpha increases expression
multiple interactions		 ISO Amiodarone results in increased expression of HEXA mRNA
Amiodarone results in increased activity of and results in increased secretion of HEXA protein		 CTD PMID:25881747 NCBI chr 8:59,936,526...59,961,654
Ensembl chr 8:59,936,660...59,962,013 		JBrowse link
G Hexb hexosaminidase subunit beta multiple interactions ISO Amiodarone results in increased activity of and results in increased secretion of HEXB protein CTD PMID:25881747 NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223 		JBrowse link
G Hexim1 HEXIM P-TEFb complex subunit 1 increases expression ISO Amiodarone results in increased expression of HEXIM1 mRNA CTD PMID:19774075 NCBI chr10:88,062,808...88,064,920
Ensembl chr10:88,062,803...88,066,189 		JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Amiodarone affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323 		JBrowse link
G Hgfac HGF activator increases expression ISO Amiodarone results in increased expression of HGFAC mRNA CTD PMID:19774075 NCBI chr14:75,707,588...75,714,182
Ensembl chr14:75,707,591...75,714,278 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Amiodarone results in decreased expression of HIF1A mRNA CTD PMID:35641671 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hira histone cell cycle regulator increases expression ISO Amiodarone results in increased expression of HIRA mRNA CTD PMID:19774075 NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529 		JBrowse link
G Hjv hemojuvelin BMP co-receptor increases expression ISO Amiodarone results in increased expression of HJV mRNA CTD PMID:24535564 NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850 		JBrowse link
G Hmgb2 high mobility group box 2 affects expression EXP Amiodarone affects the expression of HMGB2 mRNA CTD PMID:18355885 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Amiodarone results in increased expression of HMGCR mRNA CTD PMID:24489787 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression EXP Amiodarone results in increased expression of HMGCS1 mRNA CTD PMID:22291062 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Amiodarone affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254 		JBrowse link
G Hmgxb4 HMG-box containing 4 increases expression ISO Amiodarone results in increased expression of HMGXB4 mRNA CTD PMID:19774075 NCBI chr19:13,364,741...13,403,563
Ensembl chr19:13,364,807...13,403,563 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression		 ISO
EXP		 Amiodarone results in increased expression of HMOX1 mRNA
Amiodarone affects the expression of HMOX1 mRNA		 CTD PMID:18020914 PMID:19224547 PMID:19774075 PMID:25659768 PMID:31324950 More... NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnf4a hepatocyte nuclear factor 4, alpha increases expression ISO Amiodarone results in increased expression of HNF4A mRNA CTD PMID:24489787 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
G Hnf4g hepatocyte nuclear factor 4, gamma increases expression ISO Amiodarone results in increased expression of HNF4G mRNA CTD PMID:19774075 NCBI chr 2:97,885,773...98,036,650
Ensembl chr 2:97,887,432...98,036,592 		JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 increases expression ISO Amiodarone results in increased expression of HNRNPA1 mRNA CTD PMID:21163907 NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609 		JBrowse link
G Hoxb6 homeo box B6 increases expression ISO Amiodarone results in increased expression of HOXB6 mRNA CTD PMID:19774075 NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449 		JBrowse link
G Hoxc4 homeo box C4 increases expression ISO Amiodarone results in increased expression of HOXC4 mRNA CTD PMID:19774075 NCBI chr 7:134,135,279...134,173,133
Ensembl chr 7:134,170,591...134,173,133 		JBrowse link
G Hpn hepsin increases expression ISO Amiodarone results in increased expression of HPN mRNA CTD PMID:15342952 PMID:17567588 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Amiodarone affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Amiodarone affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019 		JBrowse link
G Hrk harakiri, BCL2 interacting protein increases expression ISO Amiodarone results in increased expression of HRK mRNA CTD PMID:19774075 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hscb HscB mitochondrial iron-sulfur cluster co-chaperone increases expression ISO Amiodarone results in increased expression of HSCB mRNA CTD PMID:24535564 NCBI chr12:45,821,527...45,831,902
Ensembl chr12:45,821,555...45,831,909 		JBrowse link
G Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 increases expression ISO Amiodarone results in increased expression of HSD17B11 mRNA CTD PMID:24535564 NCBI chr14:5,693,304...5,743,157
Ensembl chr14:5,711,964...5,743,161 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Amiodarone affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Amiodarone affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO Amiodarone results in increased expression of HSPA5 mRNA; Amiodarone results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Amiodarone results in increased expression of HSPA5 protein]
1-(3,4-dihydroxyphenyl)-2-thiocyanate-ethanone inhibits the reaction [Amiodarone results in increased expression of HSPA5 mRNA]		 CTD PMID:25295624 PMID:34259586 PMID:36586010 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Amiodarone results in increased expression of HSPD1 protein CTD PMID:16538043 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Amiodarone results in increased expression of HTATIP2 mRNA CTD PMID:24535564 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629 		JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Amiodarone affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Htra2 HtrA serine peptidase 2 increases expression ISO Amiodarone results in increased expression of HTRA2 mRNA CTD PMID:24489787 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Hus1 HUS1 checkpoint clamp component increases expression ISO Amiodarone results in increased expression of HUS1 mRNA CTD PMID:19774075 NCBI chr14:83,688,702...83,703,466
Ensembl chr14:83,688,708...83,703,442 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression
multiple interactions		 ISO Amiodarone results in increased expression of ICAM1 mRNA
[Amiodarone co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein		 CTD PMID:19774075 PMID:22785256 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO Amiodarone results in increased expression of ID2 mRNA CTD PMID:23397585 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 increases expression ISO Amiodarone results in increased expression of IDH2 mRNA CTD PMID:24489787 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression		 EXP
ISO		 [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Losartan inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Prednisolone inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]; Vitamin D inhibits the reaction [Amiodarone results in decreased expression of IFNG protein]
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]		 CTD PMID:25073960 PMID:34590760 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Amiodarone affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit increases expression
affects expression		 ISO
EXP		 Amiodarone results in increased expression of IGFALS mRNA
Amiodarone affects the expression of IGFALS mRNA		 CTD PMID:19483382 PMID:19774075 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Amiodarone results in increased expression of IGFBP1 mRNA CTD PMID:27089845 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Amiodarone affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937 		JBrowse link
G Igsf8 immunoglobulin superfamily, member 8 increases expression ISO Amiodarone results in increased expression of IGSF8 mRNA CTD PMID:19774075 NCBI chr13:84,770,348...84,781,534
Ensembl chr13:84,770,279...84,778,576 		JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions		 ISO Amiodarone results in decreased expression of IL10 mRNA; Amiodarone results in decreased expression of IL10 protein
ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in decreased expression of IL10 mRNA]]		 CTD PMID:34434487 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO Amiodarone results in increased expression of IL10RA mRNA CTD PMID:19774075 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] CTD PMID:25900201 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions		 ISO Amiodarone results in increased expression of IL1A mRNA
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone		 CTD PMID:19362101 PMID:19774075 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO
EXP		 [Amiodarone co-treated with Dexamethasone] results in decreased expression of IL1B mRNA
Amiodarone results in increased expression of IL1B mRNA
ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL1B mRNA]]
Amiodarone results in increased expression of IL1B mRNA; Amiodarone results in increased expression of IL1B protein		 CTD PMID:25580480 PMID:25900201 PMID:34434487 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein] CTD PMID:25073960 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il33 interleukin 33 affects expression EXP Amiodarone affects the expression of IL33 mRNA CTD PMID:18355885 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 multiple interactions EXP
ISO		 [Vitamin D co-treated with Losartan] inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL4 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL4 protein]
Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]		 CTD PMID:25073960 PMID:34590760 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 increases expression
increases secretion
multiple interactions		 ISO
EXP		 Amiodarone results in increased expression of IL6 mRNA; Amiodarone results in increased expression of IL6 protein
Amiodarone results in increased secretion of IL6 protein
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Amiodarone; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]; ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; CTNNB1 protein affects the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 protein]]; IWR-1 compound inhibits the reaction [ADM2 protein inhibits the reaction [Amiodarone results in increased expression of IL6 mRNA]]; Prednisolone inhibits the reaction [Amiodarone results in increased secretion of IL6 protein]
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Losartan inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased expression of IL6 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of IL6 protein]		 CTD PMID:11288978 PMID:19362101 PMID:34434487 PMID:34590760 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Amiodarone affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313 		JBrowse link
G Inhba inhibin subunit beta A decreases expression ISO Amiodarone results in decreased expression of INHBA mRNA CTD PMID:24535564 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Inhbe inhibin subunit beta E affects expression
increases expression		 EXP
ISO		 Amiodarone affects the expression of INHBE mRNA
Amiodarone results in increased expression of INHBE mRNA		 CTD PMID:15342952 PMID:17175557 PMID:17567588 PMID:19483382 PMID:19774075 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Inka2 inka box actin regulator 2 increases expression ISO Amiodarone results in increased expression of INKA2 mRNA CTD PMID:19774075 NCBI chr 2:193,185,275...193,200,643
Ensembl chr 2:193,185,275...193,200,642 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase increases expression ISO Amiodarone results in increased expression of IPPK mRNA CTD PMID:19774075 NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO Amiodarone results in increased expression of IRAK2 mRNA CTD PMID:19774075 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO Amiodarone results in increased expression of IRF1 mRNA CTD PMID:19774075 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Isx intestine-specific homeobox increases expression ISO Amiodarone results in increased expression of ISX mRNA CTD PMID:19774075 NCBI chr19:13,217,637...13,239,754
Ensembl chr19:13,218,552...13,239,760 		JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Amiodarone affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979 		JBrowse link
G Itgb5 integrin subunit beta 5 decreases expression ISO Amiodarone results in decreased expression of ITGB5 mRNA CTD PMID:23397585 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 increases expression ISO Amiodarone results in increased expression of ITIH2 mRNA CTD PMID:19774075 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Amiodarone affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708 		JBrowse link
G Ivns1abp influenza virus NS1A binding protein increases expression EXP Amiodarone results in increased expression of IVNS1ABP mRNA CTD PMID:17991464 NCBI chr13:63,427,040...63,446,701
Ensembl chr13:63,427,041...63,446,701 		JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Amiodarone affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jakmip3 janus kinase and microtubule interacting protein 3 increases expression ISO Amiodarone results in increased expression of JAKMIP3 mRNA CTD PMID:19774075 NCBI chr 1:193,753,134...193,881,105
Ensembl chr 1:193,811,513...193,881,104 		JBrowse link
G Jrkl JRK-like increases expression ISO Amiodarone results in increased expression of JRKL mRNA CTD PMID:19774075 NCBI chr 8:10,224,172...10,227,068
Ensembl chr 8:10,224,172...10,227,068 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
increases phosphorylation		 EXP
ISO		 Amiodarone results in increased expression of JUN mRNA; Amiodarone results in increased expression of JUN protein
[FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]
Amiodarone results in increased phosphorylation of JUN protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of JUN protein]		 CTD PMID:11597910 PMID:17214612 PMID:25073960 PMID:34590760 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 increases expression ISO Amiodarone results in increased expression of KCNA4 mRNA CTD PMID:15520326 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 decreases expression ISO
EXP		 Amiodarone results in decreased expression of KCNA5 mRNA CTD PMID:8973384 PMID:9302343 PMID:15520326 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 increases expression ISO Amiodarone results in increased expression of KCNAB1 mRNA CTD PMID:15520326 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
G Kcnb1 potassium voltage-gated channel subfamily B member 1 decreases expression ISO Amiodarone results in decreased expression of KCNB1 mRNA CTD PMID:15520326 NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression ISO Amiodarone results in decreased expression of KCND2 mRNA CTD PMID:15520326 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728 		JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 increases expression ISO Amiodarone results in increased expression of KCNE3 mRNA CTD PMID:15520326 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020 		JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 increases expression ISO Amiodarone results in increased expression of KCNE5 mRNA CTD PMID:19774075 NCBI chr  X:105,930,398...105,931,013
Ensembl chr  X:105,930,398...105,931,013 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 affects activity
multiple interactions
decreases activity
increases expression		 ISO
EXP		 Amiodarone affects the activity of KCNH2 protein
Amiodarone binds to and results in decreased activity of KCNH2 protein; Amiodarone inhibits the reaction [KCNH2 protein results in increased transport of Thallium]; Amiodarone promotes the reaction [naringenin results in decreased activity of KCNH2 protein]; naringenin promotes the reaction [Amiodarone results in decreased activity of KCNH2 protein]; Potassium inhibits the reaction [Amiodarone results in decreased activity of KCNH2 protein]
Amiodarone results in increased expression of KCNH2 mRNA		 CTD PMID:10208308 PMID:11238279 PMID:15272206 PMID:15618689 PMID:15671647 More... NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 increases expression ISO Amiodarone results in increased expression of KCNJ2 mRNA CTD PMID:19774075 NCBI chr10:96,060,834...96,071,397
Ensembl chr10:96,060,821...96,071,445 		JBrowse link
G Kcnk1 potassium two pore domain channel subfamily K member 1 increases expression ISO Amiodarone results in increased expression of KCNK1 mRNA CTD PMID:15520326 NCBI chr19:53,959,411...53,997,726
Ensembl chr19:53,959,657...53,997,724 		JBrowse link
G Kcnk12 potassium two pore domain channel subfamily K member 12 increases expression ISO Amiodarone results in increased expression of KCNK12 mRNA CTD PMID:19774075 NCBI chr 6:6,740,147...6,790,664
Ensembl chr 6:6,739,991...6,790,661 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 increases expression ISO Amiodarone results in increased expression of KCNMA1 mRNA CTD PMID:19774075 NCBI chr15:302,480...1,007,675
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kctd14 potassium channel tetramerization domain containing 14 increases expression ISO Amiodarone results in increased expression of KCTD14 mRNA CTD PMID:19774075 NCBI chr 1:151,761,688...151,766,693
Ensembl chr 1:151,761,663...151,766,691 		JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Amiodarone affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153 		JBrowse link
G Kdr kinase insert domain receptor affects expression EXP Amiodarone affects the expression of KDR mRNA CTD PMID:19483382 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression EXP Amiodarone results in decreased expression of KEAP1 mRNA CTD PMID:17991464 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 increases expression ISO Amiodarone results in increased expression of KHDRBS3 mRNA CTD PMID:24535564 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460 		JBrowse link
G Kif16b kinesin family member 16B increases expression ISO Amiodarone results in increased expression of KIF16B mRNA CTD PMID:19774075 NCBI chr 3:129,974,692...130,254,194
Ensembl chr 3:129,974,800...130,254,019 		JBrowse link
G Kif17 kinesin family member 17 increases expression ISO Amiodarone results in increased expression of KIF17 mRNA CTD PMID:19774075 NCBI chr 5:150,482,288...150,521,471
Ensembl chr 5:150,481,578...150,519,638 		JBrowse link
G Kifc1 kinesin family member C1 increases expression ISO Amiodarone results in increased expression of KIFC1 mRNA CTD PMID:19774075 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105 		JBrowse link
G Kitlg KIT ligand increases expression ISO Amiodarone results in increased expression of KITLG mRNA CTD PMID:19774075 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
G Klf10 KLF transcription factor 10 increases expression ISO Amiodarone results in increased expression of KLF10 mRNA CTD PMID:19774075 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994 		JBrowse link
G Klf15 KLF transcription factor 15 increases expression ISO Amiodarone results in increased expression of KLF15 mRNA CTD PMID:19774075 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Klf16 KLF transcription factor 16 increases expression ISO Amiodarone results in increased expression of KLF16 mRNA CTD PMID:19774075 NCBI chr 7:9,138,503...9,148,322
Ensembl chr 7:9,138,503...9,148,317 		JBrowse link
G Klf4 KLF transcription factor 4 increases expression ISO Amiodarone results in increased expression of KLF4 mRNA CTD PMID:19774075 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klhl28 kelch-like family member 28 increases expression ISO Amiodarone results in increased expression of KLHL28 mRNA CTD PMID:19774075 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164 		JBrowse link
G Klk14 kallikrein related-peptidase 14 increases expression ISO Amiodarone results in increased expression of KLK14 mRNA CTD PMID:19774075 NCBI chr 1:94,123,131...94,137,239
Ensembl chr 1:94,131,998...94,137,240 		JBrowse link
G Krt17 keratin 17 increases expression ISO Amiodarone results in increased expression of KRT17 mRNA CTD PMID:19774075 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392 		JBrowse link
G Krt23 keratin 23 increases expression ISO Amiodarone results in increased expression of KRT23 mRNA CTD PMID:24535564 NCBI chr10:84,434,445...84,450,773
Ensembl chr10:84,434,380...84,450,983 		JBrowse link
G Krt8 keratin 8 affects expression EXP Amiodarone affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 increases expression ISO Amiodarone results in increased expression of L3MBTL1 mRNA CTD PMID:19774075 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233 		JBrowse link
G Lama2 laminin subunit alpha 2 increases expression ISO Amiodarone results in increased expression of LAMA2 mRNA CTD PMID:24489787 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Lars2 leucyl-tRNA synthetase 2, mitochondrial increases expression ISO Amiodarone results in increased expression of LARS2 mRNA CTD PMID:24489787 NCBI chr 8:123,010,271...123,106,395
Ensembl chr 8:123,010,293...123,106,395 		JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression
increases expression		 EXP Amiodarone affects the expression of LCAT mRNA
Amiodarone results in increased expression of LCAT mRNA		 CTD PMID:19483382 PMID:22291062 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Amiodarone affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112 		JBrowse link
G Lctl lactase-like increases expression ISO Amiodarone results in increased expression of LCTL mRNA CTD PMID:19774075 NCBI chr 8:64,618,356...64,654,851
Ensembl chr 8:64,618,350...64,639,357 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases expression		 ISO
EXP		 Amiodarone promotes the reaction [Triiodothyronine results in increased expression of LDLR mRNA]
Triiodothyronine inhibits the reaction [Amiodarone results in decreased expression of LDLR protein]
Amiodarone results in decreased expression of LDLR mRNA
Amiodarone results in decreased expression of LDLR mRNA; Amiodarone results in decreased expression of LDLR protein		 CTD PMID:8137927 PMID:9071962 PMID:9712728 PMID:9751232 PMID:12538616 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor increases expression ISO Amiodarone results in increased expression of LHCGR mRNA CTD PMID:19774075 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Amiodarone results in increased expression of LIF mRNA CTD PMID:19774075 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lin7a lin-7 homolog A, crumbs cell polarity complex component increases expression ISO Amiodarone results in increased expression of LIN7A mRNA CTD PMID:19774075 NCBI chr 7:42,586,704...42,742,609
Ensembl chr 7:42,586,719...42,730,550 		JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Amiodarone affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464 		JBrowse link
G Lipe lipase E, hormone sensitive type multiple interactions
increases phosphorylation		 ISO INS inhibits the reaction [Amiodarone results in increased phosphorylation of LIPE protein] CTD PMID:28962527 PMID:34259586 NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310 		JBrowse link
G LOC103689958 olfactory receptor 49-like increases expression ISO Amiodarone results in increased expression of OR6T1 mRNA CTD PMID:19774075 NCBI chr 1:65,911,907...65,913,255
Ensembl chr 1:65,912,105...65,913,079 		JBrowse link
G Lox lysyl oxidase affects expression EXP Amiodarone affects the expression of LOX mRNA CTD PMID:18355885 PMID:19483382 NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477 		JBrowse link
G Lpcat3 lysophosphatidylcholine acyltransferase 3 increases expression ISO Amiodarone results in increased expression of LPCAT3 mRNA CTD PMID:24489787 NCBI chr 4:157,468,397...157,509,889
Ensembl chr 4:157,468,290...157,509,880 		JBrowse link
G Lpgat1 lysophosphatidylglycerol acyltransferase 1 increases expression EXP Amiodarone results in increased expression of LPGAT1 mRNA CTD PMID:22291062 NCBI chr13:103,294,622...103,365,372
Ensembl chr13:103,294,528...103,362,333 		JBrowse link
G Lpin3 lipin 3 increases expression ISO Amiodarone results in increased expression of LPIN3 mRNA CTD PMID:24489787 NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327 		JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Amiodarone affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110 		JBrowse link
G Lrp5 LDL receptor related protein 5 increases expression ISO Amiodarone results in increased expression of LRP5 mRNA CTD PMID:19774075 NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581 		JBrowse link
G Lss lanosterol synthase increases expression
affects expression		 EXP
ISO		 Amiodarone results in increased expression of LSS mRNA
Amiodarone affects the expression of LSS mRNA		 CTD PMID:15342952 PMID:17567588 PMID:19224547 PMID:22291062 PMID:24489787 More... NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Ly6d lymphocyte antigen 6 family member D increases expression ISO Amiodarone results in increased expression of LY6D mRNA CTD PMID:24489787 NCBI chr 7:106,643,225...106,644,733
Ensembl chr 7:106,643,232...106,644,733 		JBrowse link
G Lyz2 lysozyme 2 increases expression ISO Amiodarone results in increased expression of LYZ mRNA CTD PMID:19774075 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Macrod2 mono-ADP ribosylhydrolase 2 increases expression ISO Amiodarone results in increased expression of MACROD2 mRNA CTD PMID:19774075 NCBI chr 3:127,720,066...129,737,511
Ensembl chr 3:127,720,181...129,734,492 		JBrowse link
G Macroh2a1 macroH2A.1 histone affects expression EXP Amiodarone affects the expression of MACROH2A1 mRNA CTD PMID:18355885 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Amiodarone results in increased expression of MAFF mRNA CTD PMID:36586010 NCBI chr 7:110,912,367...110,923,711
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Amiodarone results in increased expression of MAFG mRNA CTD PMID:19774075 PMID:36586010 NCBI chr10:105,903,307...105,911,808
Ensembl chr10:105,903,237...105,912,026 		JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Amiodarone affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389 		JBrowse link
G Manba mannosidase beta affects expression EXP Amiodarone affects the expression of MANBA mRNA CTD PMID:18355885 NCBI chr 2:223,910,432...224,002,988
Ensembl chr 2:223,910,432...224,002,983 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation
multiple interactions		 ISO Amiodarone results in increased lipidation of MAP1LC3B protein
Amiodarone results in increased expression of and results in increased lipidation of MAP1LC3B protein; Amiodarone results in increased lipidation of and results in increased localization of MAP1LC3B protein		 CTD PMID:25881747 PMID:32651653 PMID:37661063 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO MAP2K1 protein inhibits the reaction [Amiodarone results in decreased expression of SNAI1 protein] CTD PMID:26515726 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Amiodarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation		 EXP
ISO		 [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK1 protein]
Amiodarone results in decreased phosphorylation of MAPK1 protein		 CTD PMID:26515726 PMID:31071512 PMID:34590760 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation
multiple interactions		 EXP Amiodarone results in increased phosphorylation of MAPK14 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK14 protein]		 CTD PMID:34590760 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
decreases phosphorylation		 EXP
ISO		 Amiodarone results in increased phosphorylation of MAPK3 protein
[Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Losartan inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Prednisolone inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased phosphorylation of MAPK3 protein]
Amiodarone results in decreased phosphorylation of MAPK3 protein		 CTD PMID:26515726 PMID:31071512 PMID:34590760 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 ISO Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein]
Amiodarone results in increased phosphorylation of MAPK8 protein		 CTD PMID:25073960 PMID:34259586 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Masp1 MBL associated serine protease 1 increases expression ISO Amiodarone results in increased expression of MASP1 mRNA CTD PMID:19774075 NCBI chr11:77,334,794...77,405,271
Ensembl chr11:77,334,859...77,402,974 		JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Amiodarone affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580 		JBrowse link
G Mbp myelin basic protein affects expression EXP Amiodarone affects the expression of MBP mRNA CTD PMID:25659768 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Amiodarone results in increased expression of MCAM mRNA CTD PMID:19774075 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mcf2 MCF.2 cell line derived transforming sequence increases expression ISO Amiodarone results in increased expression of MCF2 mRNA CTD PMID:19774075 NCBI chr  X:138,414,077...138,514,828
Ensembl chr  X:138,409,256...138,514,446 		JBrowse link
G Me1 malic enzyme 1 increases expression
affects expression		 EXP Amiodarone results in increased expression of ME1 protein
Amiodarone affects the expression of ME1 mRNA		 CTD PMID:16538043 PMID:19483382 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Med11 mediator complex subunit 11 increases expression ISO Amiodarone results in increased expression of MED11 mRNA CTD PMID:19774075 NCBI chr10:55,164,322...55,165,940
Ensembl chr10:55,164,326...55,166,533 		JBrowse link
G Mef2c myocyte enhancer factor 2C increases expression ISO Amiodarone results in increased expression of MEF2C mRNA CTD PMID:19774075 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mfhas1 multifunctional ROCO family signaling regulator 1 increases expression
decreases expression		 ISO Amiodarone results in increased expression of MFHAS1 mRNA
Amiodarone results in decreased expression of MFHAS1 mRNA		 CTD PMID:19774075 PMID:24535564 NCBI chr16:56,545,462...56,633,649
Ensembl chr16:56,546,207...56,633,743 		JBrowse link
G Mfn2 mitofusin 2 increases expression ISO Amiodarone results in increased expression of MFN2 mRNA CTD PMID:24489787 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mfsd1 major facilitator superfamily domain containing 1 decreases expression EXP Amiodarone results in decreased expression of MFSD1 mRNA CTD PMID:17991464 NCBI chr 2:151,846,130...151,866,168
Ensembl chr 2:151,846,146...151,867,045 		JBrowse link
G Mgat4a alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A increases expression ISO Amiodarone results in increased expression of MGAT4A mRNA CTD PMID:19774075 NCBI chr 9:39,673,427...39,786,747
Ensembl chr 9:39,673,430...39,766,890 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Amiodarone results in increased expression of MGST1 mRNA CTD PMID:19774075 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 increases expression ISO Amiodarone results in increased expression of MGST3 mRNA CTD PMID:24535564 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411 		JBrowse link
G Micall2 MICAL-like 2 increases expression ISO Amiodarone results in increased expression of MICALL2 mRNA CTD PMID:19774075 NCBI chr12:14,899,188...14,927,949
Ensembl chr12:14,899,157...14,927,946 		JBrowse link
G Mid2 midline 2 increases expression ISO Amiodarone results in increased expression of MID2 mRNA CTD PMID:19774075 NCBI chr  X:104,354,692...104,456,757
Ensembl chr  X:104,355,316...104,453,473 		JBrowse link
G Mipep mitochondrial intermediate peptidase increases expression ISO Amiodarone results in increased expression of MIPEP mRNA CTD PMID:24489787 NCBI chr15:34,926,198...35,051,722
Ensembl chr15:34,926,207...35,051,727 		JBrowse link
G Mir16 microRNA 16 decreases expression EXP Amiodarone results in decreased expression of MIR16 mRNA CTD PMID:17991464 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443 		JBrowse link
G Mir224 microRNA 224 decreases expression ISO
EXP		 Amiodarone decreased expression of miR224 in a human hepatoma cell line
Amiodarone decreased expression of miR224 in rat liver tumors		 RGD PMID:23913306 PMID:23913306 RGD:18182923, RGD:18182923 NCBI chr  X:150,065,088...150,065,169
Ensembl chr  X:150,065,088...150,065,169 		JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Amiodarone results in increased expression of MITF mRNA CTD PMID:19774075 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Mlx MAX dimerization protein MLX affects expression EXP Amiodarone affects the expression of MLX mRNA CTD PMID:18355885 NCBI chr10:86,019,216...86,024,326
Ensembl chr10:86,019,588...86,032,350 		JBrowse link
G Mlxipl MLX interacting protein-like decreases expression ISO Amiodarone results in decreased expression of MLXIPL mRNA CTD PMID:28962527 NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112 		JBrowse link
G Mlycd malonyl-CoA decarboxylase increases expression ISO Amiodarone results in increased expression of MLYCD mRNA CTD PMID:24489787 NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793 		JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression EXP Amiodarone affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046 		JBrowse link
G Morn5 MORN repeat containing 5 increases expression ISO Amiodarone results in increased expression of MORN5 mRNA CTD PMID:19774075 NCBI chr 3:19,402,221...19,430,075
Ensembl chr 3:19,401,801...19,430,083 		JBrowse link
G Mpi mannose phosphate isomerase increases expression ISO Amiodarone results in increased expression of MPI mRNA CTD PMID:19774075 NCBI chr 8:57,947,883...57,956,205
Ensembl chr 8:57,947,893...57,956,150