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Gene: Dctn1 (dynactin subunit 1) Rattus norvegicus
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Symbol: Dctn1
Name: dynactin subunit 1
Description: Exhibits identical protein binding activity and microtubule binding activity. Predicted to be involved in several processes, including melanosome transport; microtubule cytoskeleton organization; and regulation of microtubule cytoskeleton organization. Localizes to the cytoplasmic dynein complex. Predicted to colocalize with the retromer complex. Biomarker of synucleinopathy. Human ortholog(s) of this gene implicated in Perry syndrome and amyotrophic lateral sclerosis type 1. Orthologous to human DCTN1 (dynactin subunit 1); PARTICIPATES IN mitochondria transport pathway; N-cadherin signaling pathway; Huntington's disease pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 150 kDa dynein-associated polypeptide; DAP-150; DP-150; dynactin 1; p150-glued
Orthologs:
Homo sapiens (human) : DCTN1 (dynactin subunit 1)  HGNC  Alliance
Mus musculus (house mouse) : Dctn1 (dynactin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dctn1 (dynactin subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DCTN1 (dynactin subunit 1)
Canis lupus familiaris (dog) : DCTN1 (dynactin subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dctn1 (dynactin subunit 1)
Sus scrofa (pig) : DCTN1 (dynactin subunit 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04114,876,770 - 114,896,567 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04179,465,836 - 179,485,633 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,390,323 - 117,410,119 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14117,634,803 - 117,654,601 (+)NCBI
Celera4104,678,158 - 104,697,955 (+)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dctn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62038
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.