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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Reperfusion Injury
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Accession:DOID:9004009 term browser browse the term
Definition:Adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to the tissue (REPERFUSION), including swelling; HEMORRHAGE; NECROSIS; and damage from FREE RADICALS. The most common instance is MYOCARDIAL REPERFUSION INJURY.
Synonyms:exact_synonym: Ischemia Reperfusion Injury;   Ischemia-Reperfusion Injuries;   Reperfusion Damage;   Reperfusion Damages;   Reperfusion Injuries
 primary_id: MESH:D015427
 xref: EFO:0002687


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Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 IEP mRNA, protein:increased expression:brain, neuron RGD PMID:16997484 RGD:2301088 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 IEP mRNA, protein:increased expression, altered localization:small intestine RGD PMID:18451542 RGD:2315580 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Ace angiotensin I converting enzyme IMP RGD PMID:20436217 RGD:2325213 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 IEP mRNA:increased expression:hippocampal granule cell RGD PMID:19647005 RGD:2315956 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I IEP mRNA:decreased expression:dentate gyrus (rat) RGD PMID:19647005 RGD:2315956 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 IEP RGD PMID:12225880 RGD:2314400 NCBI chr19:24,202,405...24,244,137
Ensembl chr19:24,204,360...24,244,139 		JBrowse link
G Adgrl3 adhesion G protein-coupled receptor L3 IEP RGD PMID:12225880 RGD:2314400 NCBI chr14:26,336,320...27,104,060
Ensembl chr14:26,368,277...27,105,860 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing IMP associated with Non-alcoholic Fatty Liver Disease; RGD PMID:18098300 RGD:5686804 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin IEP protein:increased expression:plasma: RGD PMID:17263982 RGD:7364988 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adora2a adenosine A2a receptor IDA
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:27757725 PMID:17937935 RGD:4890367 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adora2b adenosine A2B receptor ISO CTD Direct Evidence: therapeutic CTD PMID:27757725 NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772 		JBrowse link
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:20451506 RGD:5129116 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:14630341 PMID:18336819 RGD:1598754, RGD:4145097 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 IDA RGD PMID:22920387 RGD:6903870 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Aif1 allograft inflammatory factor 1 IEP protein:increased expression:Kupffer cell (rat) RGD PMID:16500929 RGD:2313040 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 ISO RGD PMID:21351045 RGD:5509067 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt1s1 AKT1 substrate 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16397181 NCBI chr 1:95,333,186...95,339,678
Ensembl chr 1:95,332,898...95,339,677 		JBrowse link
G Alb albumin IEP mRNA, protein:increased expression:brain RGD PMID:20193666 RGD:2325686 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A IEP RGD PMID:10395295 RGD:1599061 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type IEP RGD PMID:15518705 RGD:5509617 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase ISO RGD PMID:18635843 RGD:5509608 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase IEP
ISO
IMP		 protein:increased expression:cerebral hemisphere
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15266012 PMID:14769366 PMID:19816089 RGD:1626152, RGD:2317531 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Ang angiogenin IEP protein:increased expression:brain RGD PMID:19666176 RGD:2325717 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Angpt1 angiopoietin 1 ISO RGD PMID:19885826 RGD:2316041 NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067 		JBrowse link
G Aoc3 amine oxidase, copper containing 3 IMP RGD PMID:16339390 RGD:2313821 NCBI chr10:86,272,757...86,280,702 JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 IEP RGD PMID:18205898 RGD:2292105 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:increased expression:placenta RGD PMID:18373555 RGD:2315671 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Aqp4 aquaporin 4 IEP
ISO		 protein:increased expression:cerebral cortex
mRNA, protein:increased expression:parietal cortex		 RGD PMID:20979759 PMID:21718723 PMID:19806476 PMID:20924629 RGD:5148016, RGD:5684013, RGD:5148037, RGD:5148022 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Arg1 arginase 1 IEP protein:increased expression:serum (rat) RGD PMID:17023552 RGD:4143185 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Asl argininosuccinate lyase resistance IEP protein:increased expression:brain, neuron (rat) RGD PMID:17198704 RGD:1599263 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662 		JBrowse link
G Ass1 argininosuccinate synthase 1 resistance IEP protein:increased expression:brain, neuron (rat) RGD PMID:17198704 RGD:1599263 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Bad BCL2-associated agonist of cell death IEP protein:altered localization:brain, mitochondria RGD PMID:18347331 RGD:2292679 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bag1 BAG cochaperone 1 IMP RGD PMID:12215270 RGD:2296021 NCBI chr 5:56,068,494...56,081,075
Ensembl chr 5:56,068,494...56,081,075 		JBrowse link
G Bag3 BAG cochaperone 3 IEP protein:increased expression:hippocampus, astrocyte RGD PMID:12061864 RGD:2325848 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP protein:increased expression:brain RGD PMID:18083315 PMID:18221257 RGD:2290557, RGD:2293026 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: therapeutic CTD PMID:15449323 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor IEP mRNA:increased expression:retina RGD PMID:20554625 RGD:4891135 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:brain RGD PMID:22306244 RGD:6483054 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist IDA RGD PMID:19888517 RGD:2317562 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 IEP
IMP		 protein:increased expression:brain RGD PMID:18159002 PMID:18053646 RGD:2293126, RGD:2293127 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bmp6 bone morphogenetic protein 6 IEP RGD PMID:11245809 RGD:2289024 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 IEP mRNA:increased expression:dentate gyrus, granule cell RGD PMID:10996456 RGD:5129486 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Bsg basigin (Ok blood group) IEP protein:increased expression:basal ganglia RGD PMID:16029217 RGD:2289063 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:kidney RGD PMID:9712737 RGD:2289078 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C3 complement C3 IEP protein:increased expression:intestine RGD PMID:17981193 RGD:5129536 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C3ar1 complement C3a receptor 1 IMP RGD PMID:15159277 RGD:5129702 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701 		JBrowse link
G C5 complement C5 IDA RGD PMID:15158333 RGD:1600597 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G C5ar1 complement C5a receptor 1 IMP RGD PMID:15158333 PMID:15159277 RGD:1600597, RGD:5129702 NCBI chr 1:76,948,622...76,959,826 JBrowse link
G Casp1 caspase 1 IMP RGD PMID:17845807 RGD:2315890 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 IEP RGD PMID:18273070 RGD:2311461 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 treatment IMP
IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23875703 PMID:18490106 PMID:29568770 RGD:2293311, RGD:13792595 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp6 caspase 6 IEP protein:increased expression, increased activity:small intestine mucosa RGD PMID:15010362 RGD:2301320 NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502 		JBrowse link
G Casp8 caspase 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 treatment IDA RGD PMID:29568770 RGD:13792595 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cast calpastatin IEP RGD PMID:11035539 RGD:5509823 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase IDA
ISO
IEP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:8215636 PMID:16682413 PMID:23743330 PMID:23875703 PMID:19196076 More... RGD:5130760, RGD:5130200 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 IEP protein:increased expression:brain RGD PMID:17293479 RGD:2289123 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 IEP mRNA:increased expression:aorta RGD PMID:9665468 RGD:4145482 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IDA
ISO		 Gastric Reperfusion Injury
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12468449 PMID:15829914 PMID:22611311 RGD:8549744 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15829914 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 ISO
IEP		 protein:increased secretion:lung, secretion (mouse)
protein:increased expression:gut		 RGD PMID:19558673 PMID:15542513 RGD:4891479, RGD:2307184 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccnb1 cyclin B1 IEP protein;altered expression:cerebral cortex, hippocampus CA1, neuron RGD PMID:18278459 RGD:2315990 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnd1 cyclin D1 IEP RGD PMID:16718823 RGD:2289145 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 IEP protein:decreased expression:liver RGD PMID:17584601 RGD:2289275 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccng1 cyclin G1 IEP mRNA, protein:increased expression:brain RGD PMID:9698156 RGD:2316027 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ISO mRNA:increased expression:kidney RGD PMID:20410256 RGD:5688141 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd2ap CD2-associated protein IEP RGD PMID:16088078 RGD:1581187 NCBI chr 9:18,086,744...18,182,744
Ensembl chr 9:18,086,984...18,182,199 		JBrowse link
G Cd36 CD36 molecule ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd40 CD40 molecule IMP RGD PMID:12388354 RGD:5508171 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand ISO
IMP		 RGD PMID:20659085 PMID:12388354 RGD:5490531, RGD:5508171 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd44 CD44 molecule IEP protein:increased expression:kidney
protein:increased expression:testis, macrophage		 RGD PMID:16786159 PMID:16891795 RGD:2289354, RGD:2289369 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd55 CD55 molecule (Cromer blood group) IEP RGD PMID:20403613 RGD:2326175 NCBI chr13:41,857,242...41,885,966
Ensembl chr13:41,857,395...41,885,831 		JBrowse link
G Cd59b CD59b molecule IDA RGD PMID:10530491 RGD:1600493 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cdc42 cell division cycle 42 IDA protein:increased activation:hippocampus CA1 RGD PMID:17161586 RGD:2298583 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16968891 PMID:10451498 RGD:10043817 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IEP protein:increased expression:skeletal muscle RGD PMID:15799773 RGD:2293627 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cfh complement factor H IEP protein:increased expression:plasma: RGD PMID:17263982 RGD:7364988 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Chat choline O-acetyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093 		JBrowse link
G Cldn4 claudin 4 IEP protein:increased expression, altered localization:small intestine epithelium RGD PMID:17375208 RGD:2317600 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19372445 RGD:2314674 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 IEP RGD PMID:17565360 RGD:5686869 NCBI chr 8:57,264,962...57,300,010
Ensembl chr 8:57,264,962...57,300,010 		JBrowse link
G Ctsb cathepsin B IEP protein:increased expression:cerebral cortex, mitochondrion (rat) RGD PMID:18938146 RGD:2315506 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsg cathepsin G ISO RGD PMID:17322378 RGD:7242055 NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP mRNA, protein:increased expression:brain RGD PMID:19563789 RGD:4891956 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 ISO
IEP		 mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16526316 PMID:20160675 PMID:10655268 RGD:5134970, RGD:5135270 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 IEP
ISO		 mRNA:increased expression:liver
protein:increased expression:respiratory system fluid/secretion
associated with Anemia, Sickle Cell;protein:increased expression:lung		 RGD PMID:18589091 PMID:16709871 PMID:19433855 RGD:2311376, RGD:5135441, RGD:5135307 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP protein:increased expression:retina RGD PMID:18709383 RGD:2306570 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IEP
ISO		 mRNA:increased expression:jejunum, lung
CTD Direct Evidence: marker/mechanism
protein:increased expression:liver
mRNA:increased expression:liver		 CTD
RGD		 PMID:12468449 PMID:19691980 PMID:10655268 PMID:11580116 PMID:20160675 RGD:5134974, RGD:5135270, RGD:5135251, RGD:5134970 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IEP protein:increased expression:liver RGD PMID:11580116 PMID:10655268 RGD:5135251, RGD:5135270 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ISO associated with Anemia, Sickle Cell;protein:increased expression:lung RGD PMID:19433855 RGD:5135307 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 IEP mRNA:increased expression:liver RGD PMID:18589091 RGD:2311376 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cyba cytochrome b-245 alpha chain IEP RGD PMID:15148062 RGD:1599683 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cybb cytochrome b-245 beta chain IEP
ISO		 Protein:increase expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19193722 PMID:16766636 RGD:1599677 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP protein:increased expression:hippocampus (rat) RGD PMID:21114983 RGD:4890041 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 IEP protein:decreased expression:liver RGD PMID:21094789 RGD:4892235 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr12:16,397,998...16,433,833
Ensembl chr12:16,397,998...16,433,833 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22749977 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 IEP protein:increased expression:kidney RGD PMID:18790177 RGD:4781446 NCBI chr  X:71,661,421...71,690,012
Ensembl chr  X:71,663,821...71,690,121 		JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 IEP protein:increased expression:brain RGD PMID:21664436 RGD:5144004 NCBI chr15:48,189,476...48,228,750
Ensembl chr15:48,189,073...48,304,136 		JBrowse link
G Dcc DCC netrin 1 receptor IEP protein:increased expression:brain RGD PMID:17574219 RGD:2314372 NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740 		JBrowse link
G Dsg1 desmoglein 1 IEP protein:decreased expression:lung RGD PMID:19500802 RGD:2316254 NCBI chr18:11,674,687...11,705,383
Ensembl chr18:11,674,402...11,703,443 		JBrowse link
G Edn1 endothelin 1 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17470888 PMID:18722366 RGD:4892577 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Edn2 endothelin 2 IEP RGD PMID:1479622 RGD:1580920 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814 		JBrowse link
G Ednrb endothelin receptor type B IEP RGD PMID:18722366 RGD:4892577 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Eef2 eukaryotic translation elongation factor 2 IEP protein:hypophosphorylation:cortex, hippocampus: RGD PMID:15211596 RGD:10401223 NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183 		JBrowse link
G Efna5 ephrin A5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 9:102,316,753...102,595,480
Ensembl chr 9:102,320,295...102,597,413 		JBrowse link
G Efnb2 ephrin B2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391 		JBrowse link
G Egf epidermal growth factor resistance ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16526316 PMID:16417467 RGD:6906916 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egr1 early growth response 1 ISO
IEP		 Lung Reperfusion Injury
CTD Direct Evidence: marker/mechanism
Lung Reperfusion Injury; protein:increased expression:lung, nucleus (rat)
Lung Reperfusion Injury; protein:increased expression:lung, nucleus (mouse)		 CTD
RGD		 PMID:12468449 PMID:16551742 PMID:16488723 PMID:19342415 RGD:5131903, RGD:5131904, RGD:5131887 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:19041636 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 IDA protein:increased phosphorylation:kidney RGD PMID:15936177 RGD:1581062 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha IDA protein:increased phosphorylation:kidney RGD PMID:15936177 RGD:1581062 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Eno2 enolase 2 IDA RGD PMID:17683050 RGD:2293745 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Ep300 E1A binding protein p300 treatment IDA
IEP		 retina
retina; protein:altered localization:Hsp70, promoter (rat)		 RGD PMID:22143029 PMID:22143029 RGD:5686888, RGD:5686888 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epha2 Eph receptor A2 IDA RGD PMID:16735461 RGD:1580976 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO RGD PMID:19471280 RGD:5688359 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit IMP RGD PMID:19440222 RGD:2313668 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G F2 coagulation factor II, thrombin IMP RGD PMID:20705928 RGD:5147777 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fas Fas cell surface death receptor treatment IDA RGD PMID:29568770 RGD:13792595 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgf1 fibroblast growth factor 1 IDA
ISO		 Rat model using human FGF1 RGD PMID:19497570 PMID:16635575 RGD:5509879, RGD:5509881 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf7 fibroblast growth factor 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit IEP
ISO		 protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:7922267 PMID:15121240 RGD:2293779 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit IEP mRNA:increased expression:hippocampus RGD PMID:15306117 RGD:1642465 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit IEP protein:increased expression:brain RGD PMID:15121240 RGD:2293779 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IEP RGD PMID:17250641 RGD:2307361 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gast gastrin ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gh1 growth hormone 1 treatment ISO RGD PMID:21439711 RGD:10003153 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide ISO CTD Direct Evidence: therapeutic CTD PMID:16581065 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Gjb1 gap junction protein, beta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25530438 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925 		JBrowse link
G Glud1 glutamate dehydrogenase 1 IEP protein:decreased activity:brain RGD PMID:7808037 RGD:6484655 NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957 		JBrowse link
G Gnai2 G protein subunit alpha i2 IEP RGD PMID:11367746 RGD:13513922 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 IEP RGD PMID:11367746 RGD:13513922 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gpt glutamic--pyruvic transaminase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8215636 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23743330 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP mRNA:decreased expression:hippocampus (rat) RGD PMID:20408958 RGD:4107069 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 IMP RGD PMID:17639597 RGD:2316528 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 IMP RGD PMID:17639597 RGD:2316528 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:20350575 RGD:2325867 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP mRNA, protein:decreased expression:cerebral cortex, hippocampus (rat) RGD PMID:20350575 RGD:2325867 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP associated with Diabetes Mellitus, Experimental RGD PMID:24904723 RGD:10401882 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO RGD PMID:17142801 RGD:6903953 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:7635938 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hgf hepatocyte growth factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IDA Spinal Cord Reperfusion Injury
Limb Reperfusion Injury		 RGD PMID:16465055 PMID:23816242 RGD:9068924, RGD:9068927 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP RGD PMID:22392147 RGD:10402071 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase IMP
ISO		 associated with Diabetes Mellitus, Experimental RGD PMID:21724106 PMID:16009498 PMID:18398369 RGD:5508445, RGD:5508473, RGD:2315888 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 IDA
ISO
IEP
IMP		 CTD Direct Evidence: marker/mechanism|therapeutic
protein:increased expression:serum, Bronchoalveolar Lavage Fluid 		CTD
RGD		 PMID:12352873 PMID:16982915 PMID:17660127 PMID:17906103 PMID:23075401 More... RGD:1582708, RGD:4145338, RGD:4145514 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:17169356 RGD:1626416 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:7922267 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B ISO
IEP		 RGD PMID:10965299 PMID:10550516 RGD:7242748, RGD:7242749 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 IMP associated with Diabetes Mellitus, experimental (D003921): protein:increased expression:brain RGD PMID:22075494 RGD:5685650 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 ISO CTD Direct Evidence: therapeutic CTD PMID:10216529 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 ISO CTD Direct Evidence: therapeutic CTD PMID:19193722 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11557319 PMID:23743330 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Id3 inhibitor of DNA binding 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Ifng interferon gamma IEP protein:increased expression:plasma RGD PMID:19514843 RGD:2308950 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO RGD PMID:16306169 RGD:1598442 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il10 interleukin 10 IEP
ISO
IDA		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18460982 PMID:19514843 PMID:12388354 PMID:16141682 RGD:2308950, RGD:5508171, RGD:1598625 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12a interleukin 12A ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il13 interleukin 13 IEP
ISO		 protein:decreased expression:plasma RGD PMID:18354382 PMID:18354382 RGD:2301685, RGD:2301685 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il18 interleukin 18 ISO protein:increased expression:serum RGD PMID:19394645 PMID:16052682 RGD:4889555, RGD:4889825 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:23875703 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:10594344 PMID:12468449 PMID:15829914 PMID:19058328 PMID:19673871 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 IEP
ISO		 CTD Direct Evidence: marker/mechanism
protein:increased expression:lung		 CTD
RGD		 PMID:15829914 PMID:17032661 PMID:18258783 PMID:19673871 PMID:21940958 More... RGD:4143250, RGD:4143253 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irf1 interferon regulatory factor 1 IEP mRNA:increased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Itga2b integrin subunit alpha 2b IMP RGD PMID:11705748 RGD:2316361 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168 		JBrowse link
G Itga5 integrin subunit alpha 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Itgb3 integrin subunit beta 3 IMP RGD PMID:11705748 RGD:2316361 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Jak2 Janus kinase 2 ISO RGD PMID:20440769 RGD:6483026 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:7922267 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:10708603 RGD:1581697 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Kdr kinase insert domain receptor IEP
ISO		 mRNA:increased expression:hippocampus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16526316 PMID:17402857 RGD:5684415 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO
IEP		 protein:decreased expression:brain, neuron, cytoplasm (mouse)
protein:decreased expression:left coronary artery (rat)		 RGD PMID:21075092 PMID:18078953 RGD:6893270, RGD:6902919 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klk1 kallikrein 1 IEP RGD PMID:12746231 RGD:1641806 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754 		JBrowse link
G Ldlr low density lipoprotein receptor IEP RGD PMID:17288738 RGD:2324630 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lep leptin IDA RGD PMID:21086559 RGD:5128549 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lig3 DNA ligase 3 IEP protein:increased expression:brain RGD PMID:17412650 RGD:2302580 NCBI chr10:67,717,808...67,741,141
Ensembl chr10:67,717,812...67,798,414 		JBrowse link
G Manf mesencephalic astrocyte-derived neurotrophic factor IEP protein:increased expression:brain RGD PMID:19773801 RGD:2325809 NCBI chr 8:107,500,856...107,551,595
Ensembl chr 8:107,548,352...107,551,438 		JBrowse link
G Map2 microtubule-associated protein 2 IEP protein:increased expression:serum RGD PMID:21948028 RGD:6483082 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20302854 PMID:16699462 RGD:1582310 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 IDA protein:increased activity:hippocampus RGD PMID:16805806 RGD:2293339 NCBI chr10:13,918,417...13,958,335
Ensembl chr10:13,918,400...13,958,273 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19667931 PMID:20302854 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mb myoglobin ISO RGD PMID:12788661 RGD:1582427 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mbl1 mannose binding lectin 1 ISO protein:decreased expression:serum RGD PMID:16982912 PMID:15509537 RGD:1582132, RGD:6903263 NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174 		JBrowse link
G Mbl2 mannose binding lectin 2 ISO protein:increased expression:serum RGD PMID:15882434 PMID:15509537 RGD:6903262, RGD:6903263 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mc1r melanocortin 1 receptor no_association ISO RGD PMID:18757499 RGD:5687323 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mdk midkine ISO RGD PMID:15780085 RGD:1582475 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase IEP mRNA:increased expression:retina (rat) RGD PMID:17113948 RGD:2317505 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mif macrophage migration inhibitory factor disease_progression ISO RGD PMID:18055556 RGD:4891010 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Mir148b microRNA 148b ISO CTD Direct Evidence: marker/mechanism CTD PMID:30308185 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494 		JBrowse link
G Mmp3 matrix metallopeptidase 3 IEP protein:increased protein, activity:brain RGD PMID:15099024 RGD:2325962 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO
IMP		 CTD Direct Evidence: marker/mechanism
associated with lung injury; mRNA, protein:increased expression:lung
protein:increased expression:limb muscle (mouse)		 CTD
RGD		 PMID:23075401 PMID:16551680 PMID:19545667 PMID:16251419 RGD:1582618, RGD:5129531, RGD:1582631 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase IEP
ISO		 protein:increased activity:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:8869312 PMID:10706834 PMID:12024109 PMID:16971220 PMID:19058328 More... RGD:5130958 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mt-atp6 mitochondrially encoded ATP synthase membrane subunit 6 IEP RGD PMID:20450733 RGD:5490294 NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 IEP RGD PMID:20450733 RGD:5490294 NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b IEP mRNA:decreased expression:kidney RGD PMID:7692737 RGD:2298967 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278 		JBrowse link
G Mt2A metallothionein 2A ISO mRNA:increased expression:cerebrum (mouse) RGD PMID:12122050 RGD:6483850 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 ISO RGD PMID:19635467 RGD:6480529 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Muc1 mucin 1, cell surface associated IEP RGD PMID:23977093 RGD:7349380 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25780291 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Nes nestin IEP protein:increased expression:cerebral cortex RGD PMID:17569338 RGD:1642074 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 IEP protein:increased expression:small intestine RGD PMID:20107953 RGD:5131440 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nos1 nitric oxide synthase 1 IMP RGD PMID:17451676 RGD:1642142 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO		 mRNA:increased expression:liver
CTD Direct Evidence: marker/mechanism
protein:increased expression:venule, arteriole, endothelium (mouse)
mRNA, protein:increased expression:liver		 CTD
RGD		 PMID:10383581 PMID:19673871 PMID:23061969 PMID:23075401 PMID:11592783 More... RGD:2325259, RGD:5509100, RGD:1580938 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21968084 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox4 NADPH oxidase 4 IEP mRNA:increased expression:cerebral cortex RGD PMID:18438942 RGD:2324666 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Oga O-GlcNAcase IMP RGD PMID:16899550 RGD:2305957 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
G Oprm1 opioid receptor, mu 1 IEP mRNA, protein:decreased expression:hippocampus RGD PMID:17360495 RGD:2316611 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Otc ornithine transcarbamylase IEP protein:increased activity:serum RGD PMID:1499453 RGD:4144083 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP RGD PMID:18403049 RGD:2304111 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased expression:liver (rat)		 CTD
RGD		 PMID:15696051 PMID:16798486 PMID:9390645 PMID:21850691 RGD:5510018, RGD:5510020 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 IEP
ISO		 RGD PMID:19142196 PMID:19142196 RGD:6483555, RGD:6483555 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Pde5a phosphodiesterase 5A IMP RGD PMID:19474186 RGD:2314462 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IMP
IEP
ISO		 protein:decreased expression:lung (rat)
protein:increased expression:brain (mouse)		 RGD PMID:12121711 PMID:21872880 PMID:22382321 RGD:2311660, RGD:6771206, RGD:6766379 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 IEP proetin:decreased dimerization:skeletal muscle (rat) RGD PMID:19100383 RGD:4108481 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Pink1 PTEN induced kinase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35312153 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Pklr pyruvate kinase L/R IEP RGD PMID:17013507 RGD:1625588 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870 		JBrowse link
G Pla2g2a phospholipase A2 group IIA ISO CTD Direct Evidence: marker/mechanism CTD PMID:12967936 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g4a phospholipase A2 group IVA IDA protein:increased activity:alveolar macrophage RGD PMID:1642455 RGD:1642456 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Plat plasminogen activator, tissue type IDA
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:9472885 PMID:15223382 RGD:2311674 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase IEP
ISO		 protein:increased expression:spinal cord (rat)
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:15181847 PMID:19663807 PMID:18586014 RGD:6483808, RGD:6483830 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor ISO RGD PMID:18606671 RGD:6483829 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pld2 phospholipase D2 IEP protein:increased expression:hippocampus CA1, hippocampus granule cell layer
mRNA:decreased expression:brainstem, cerebellum		 RGD PMID:17393174 PMID:17024567 RGD:2299901, RGD:2299902 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase ISO protein:increased expression:medulla oblongata (human) RGD PMID:21061149 RGD:5128821 NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Polb DNA polymerase beta IEP protein:increased expression:cerebral cortex RGD PMID:17412650 RGD:2302580 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IDA
ISO		 liver ischemia/reperfusion injury
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:19151258 PMID:21305343 RGD:5509942 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO CTD Direct Evidence: therapeutic CTD PMID:12468449 PMID:24011919 PMID:24433871 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha IDA RGD PMID:14762344 RGD:1580702 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Ppp3cb protein phosphatase 3 catalytic subunit beta ISO RGD PMID:14615291 RGD:1580705 NCBI chr15:3,759,950...3,804,976
Ensembl chr15:3,760,030...3,804,981 		JBrowse link
G Prdx6 peroxiredoxin 6 ISO RGD PMID:16766642 RGD:1580710 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Prkca protein kinase C, alpha IMP RGD PMID:17905752 RGD:2292474 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prss1 serine protease 1 IEP RGD PMID:11062314 RGD:1599961 NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792 		JBrowse link
G Ptafr platelet-activating factor receptor treatment ISO
IMP		 RGD PMID:12812996 PMID:11139461 RGD:1581279, RGD:10043168 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Pten phosphatase and tensin homolog IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19038262 PMID:17239858 RGD:2292538 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptges prostaglandin E synthase IEP
ISO		 RGD PMID:12431630 PMID:16864802 RGD:2300116, RGD:2300094 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10594344 PMID:16385084 RGD:5688223 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP
ISO
IMP
IDA		 protein:decreased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:10588920 PMID:10594344 PMID:11567657 PMID:16386242 PMID:18258783 More... RGD:5135045, RGD:5508180, RGD:1580660 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2 protein tyrosine kinase 2 IEP protein:increased tyrosine phosphorylation:kidney RGD PMID:17620366 RGD:2292577 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IDA protein:increased phosphorylation:hippocampus RGD PMID:15970382 RGD:1642621 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IEP
ISO		 protein:increased expression:nucleus, liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20302854 PMID:23743330 PMID:18621400 RGD:2298777 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G S100b S100 calcium binding protein B IEP RGD PMID:18840784 RGD:5508834 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 ISO RGD PMID:16403835 RGD:1580913 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Scfd1 sec1 family domain containing 1 IEP protein:increased expression:cerebral cortex RGD PMID:9195952 RGD:633771 NCBI chr 6:68,795,810...68,874,076
Ensembl chr 6:68,795,878...68,874,078 		JBrowse link
G Sele selectin E IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17112405 PMID:23743330 PMID:19489247 RGD:2313598 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741 		JBrowse link
G Sell selectin L IEP RGD PMID:19489247 RGD:2313598 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456 		JBrowse link
G Selp selectin P IEP
ISO		 RGD PMID:18521901 PMID:21701413 RGD:2312314, RGD:6218990 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Serpine2 serpin family E member 2 IEP RGD PMID:8261109 RGD:2317936 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:23991040 RGD:8661644 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Sftpc surfactant protein C IDA mRNA:decreased expression:lung RGD PMID:20560845 RGD:4144062 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Si sucrase-isomaltase IEP RGD PMID:9724271 RGD:1625550 NCBI chr 2:157,505,893...157,586,228
Ensembl chr 2:157,506,342...157,585,260 		JBrowse link
G Sirt7 sirtuin 7 ISO CTD Direct Evidence: therapeutic CTD PMID:28675767 NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP mRNA, protein:increased expression:brain RGD PMID:19781384 RGD:2313601 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 IEP mRNA, protein:increased expression:brain RGD PMID:19781384 RGD:2313601 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc30a4 solute carrier family 30 member 4 IEP mRNA:increased expression:brain RGD PMID:18289514 RGD:2299950 NCBI chr 3:109,753,270...109,775,306
Ensembl chr 3:109,753,273...109,775,306 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP protein:decreased expression:renal proximal tubule RGD PMID:15775707 RGD:2311304 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852 		JBrowse link
G Slc6a11 solute carrier family 6 member 11 IEP RGD PMID:13678673 RGD:1299345 NCBI chr 4:147,297,972...147,413,319
Ensembl chr 4:147,297,969...147,413,443 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 IEP RGD PMID:18037393 RGD:2316975 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc8a2 solute carrier family 8 member A2 IEP RGD PMID:18037393 RGD:2316975 NCBI chr 1:76,816,583...76,852,928
Ensembl chr 1:76,808,725...76,847,072 		JBrowse link
G Slc8a3 solute carrier family 8 member A3 IEP RGD PMID:18037393 RGD:2316975 NCBI chr 6:100,874,359...101,007,989
Ensembl chr 6:100,874,369...101,007,508 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:19027022 PMID:20337040 RGD:6771332 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 IEP mRNA:decreased expression:liver RGD PMID:16858290 RGD:2303111 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981 		JBrowse link
G Slk STE20-like kinase IEP protein:increased expression:kidney RGD PMID:12965890 RGD:2304069 NCBI chr 1:246,473,712...246,529,643
Ensembl chr 1:246,473,712...246,526,530 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor ISO CTD Direct Evidence: therapeutic CTD PMID:8215636 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 ISO CTD Direct Evidence: therapeutic CTD PMID:25780291 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 IDA associated with Brain Ischemia;mRNA, protein:increased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Socs4 suppressor of cytokine signaling 4 IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr15:20,523,406...20,537,889
Ensembl chr15:20,523,183...20,542,494 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:15364863 PMID:16397181 PMID:23061969 PMID:23743330 PMID:15364863 RGD:1580834 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 IEP
ISO		 protein:increased expression:liver
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:8215636 PMID:16682413 PMID:19193722 PMID:19917352 PMID:21940958 More... RGD:1582141, RGD:1581259 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 ISO RGD PMID:15778274 RGD:1581264 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:20548025 RGD:6903275 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP protein:increased phosphorylation:hippocampus CA1 (rat) RGD PMID:20197063 RGD:2325012 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA
IEP		 protein:increased serine phosphorylation:brain
protein:increased phosphorylation:kidney		 RGD PMID:15262323 PMID:17670769 RGD:1600103, RGD:2291900 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat2 signal transducer and activator of transcription 2 IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr 7:702,565...718,349
Ensembl chr 7:702,495...718,967 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21940958 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 IEP mRNA:increased expression:hippocampus RGD PMID:17880360 RGD:2303397 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Stc1 stanniocalcin 1 IEP mRNA:increased expression:cerebral cortex RGD PMID:15485913 RGD:2324700 NCBI chr15:44,299,591...44,311,695
Ensembl chr15:44,299,621...44,310,264 		JBrowse link
G Stc2 stanniocalcin 2 IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:15485913 RGD:2324700 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 IEP
ISO		 protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25922074 PMID:16908442 RGD:2302564 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275 		JBrowse link
G Tbxas1 thromboxane A synthase 1 IDA associated with Cholestasis, Extrahepatic RGD PMID:15000260 PMID:8680115 RGD:1601451, RGD:1601475 NCBI chr 4:67,664,963...67,837,096
Ensembl chr 4:67,665,007...67,837,096 		JBrowse link
G Tert telomerase reverse transcriptase ISO CTD Direct Evidence: marker/mechanism CTD PMID:16968891 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tfam transcription factor A, mitochondrial IDA RGD PMID:22266265 RGD:6767573 NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 IEP RGD PMID:15613744 RGD:1579926 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Th tyrosine hydroxylase ISO protein:increased expression:medulla oblongata (human) RGD PMID:21061149 RGD:5128821 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thbd thrombomodulin ISO RGD PMID:19342415 RGD:5131887 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thy1 Thy-1 cell surface antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25780291 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 IEP protein:decreased expression:brain RGD PMID:17551674 RGD:2290424 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tjp1 tight junction protein 1 IEP protein:decreased expression:brain, endothelial cell RGD PMID:19374856 PMID:19929946 RGD:2325135, RGD:2325127 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tlr2 toll-like receptor 2 IEP
ISO		 mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25780291 PMID:15912106 RGD:2312727 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr3 toll-like receptor 3 IEP protein:increased expression:liver (rat) RGD PMID:21355876 RGD:5128693 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr4 toll-like receptor 4 IEP
ISO		 protein:increased expression:liver
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:25780291 PMID:27064547 PMID:19473433 PMID:17126102 RGD:2312503, RGD:4144169 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 IEP protein:increased expression:liver RGD PMID:18005084 RGD:2291961 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10706834 PMID:12024109 PMID:15829914 PMID:16971220 PMID:17112405 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP RGD PMID:17109621 RGD:1624182 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tp53 tumor protein p53 IEP protein:increased expression:brain, mitochondrion RGD PMID:17661174 RGD:2290568 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 treatment IDA RGD PMID:20554625 RGD:4891135 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092 		JBrowse link
G Trpm7 transient receptor potential cation channel, subfamily M, member 7 IEP mRNA,protein:increased expression:hippocampus RGD PMID:18395621 RGD:5684390 NCBI chr 3:114,046,258...114,134,799
Ensembl chr 3:114,046,258...114,135,190 		JBrowse link
G Txn1 thioredoxin 1 IEP mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txn2 thioredoxin 2 IEP mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359 		JBrowse link
G Txnrd1 thioredoxin reductase 1 IEP mRNA:decreased expression:cerebral cortex
mRNA:decreased expression:spinal cord		 RGD PMID:19128823 PMID:19409971 RGD:5685030, RGD:5685028 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Txnrd2 thioredoxin reductase 2 IEP mRNA:decreased expression:cerebral cortex RGD PMID:19128823 RGD:5685030 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP mRNA:increased expression:kidney RGD PMID:18813897 RGD:2313108 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vegfc vascular endothelial growth factor C IEP RGD PMID:18704465 RGD:2315487 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vegfd vascular endothelial growth factor D ISO CTD Direct Evidence: marker/mechanism CTD PMID:16526316 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295 		JBrowse link
G Vim vimentin ISO CTD Direct Evidence: marker/mechanism CTD PMID:23075401 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vip vasoactive intestinal peptide ISO RGD PMID:21693218 RGD:5685379 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
G Wnt3a Wnt family member 3A ISO CTD Direct Evidence: therapeutic CTD PMID:23875703 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Xdh xanthine dehydrogenase treatment IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12910483 PMID:23403765 RGD:7247700 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 IEP protein:increased expression:brain RGD PMID:17412650 RGD:2302580 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Zfp354a zinc finger protein 354A IEP mRNA:decreased expression:kidney RGD PMID:8382778 RGD:1300202 NCBI chr10:35,396,242...35,408,069
Ensembl chr10:35,396,231...35,408,068 		JBrowse link
Cardiac Allograft Vasculopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor IEP RGD PMID:9916935 RGD:11341701 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K ISO RGD PMID:21489814 RGD:155260371 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Pdgfd platelet derived growth factor D ISO RGD PMID:19213942 RGD:9854642 NCBI chr 8:3,488,448...3,722,395
Ensembl chr 8:3,488,423...3,722,395 		JBrowse link
Chronic Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ager advanced glycosylation end product-specific receptor treatment IEP RGD PMID:22217518 PMID:23769041 RGD:7245568, RGD:8695995 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G C3 complement C3 treatment IDA RGD PMID:25122638 RGD:11040803 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cd40 CD40 molecule treatment IDA RGD PMID:22826618 RGD:11352297 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand treatment IDA liver RGD PMID:22826618 RGD:11352297 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model RGD PMID:12095034 RGD:11049508 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP RGD PMID:22217518 RGD:7245568 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 ameliorates IMP RGD PMID:24312257 RGD:401700379 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IDA RGD PMID:23985719 RGD:10041002 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Tnf tumor necrosis factor treatment IMP RGD PMID:24598936 RGD:10450586 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Chronic Allograft Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aco1 aconitase 1 IEP RGD PMID:20176611 RGD:11541086 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Alb albumin disease_progression ISO RGD PMID:24370342 RGD:11035281 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 ISO RGD PMID:17298994 RGD:7241819 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccn2 cellular communication network factor 2 disease_progression IEP mRNA, protein:increased expression:kidney (rat) RGD PMID:19921985 RGD:150517553 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Clu clusterin treatment IEP RGD PMID:22494435 RGD:9068431 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cs citrate synthase treatment IDA RGD PMID:20005400 RGD:243048470 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO RGD PMID:22845765 RGD:7241226 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp7 matrix metallopeptidase 7 treatment IDA RGD PMID:18209025 RGD:9685339 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Pdgfa platelet derived growth factor subunit A IEP RGD PMID:11889420 RGD:11080974 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA:increased expression:kidney: RGD PMID:15785371 PMID:11889420 RGD:10449491, RGD:11080974 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP RGD PMID:11889420 RGD:11080974 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IEP RGD PMID:11889420 RGD:11080974 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Plau plasminogen activator, urokinase ISO protein:increased secretion:T lymphocyte (human) RGD PMID:16387096 RGD:7241259 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO protein:increased expression:kidney: RGD PMID:16221712 RGD:13208600 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO protein:increased expression:kidney: RGD PMID:16221712 PMID:18192922 RGD:13208600, RGD:13208601 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
Chronic Lung Allograft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epas1 endothelial PAS domain protein 1 IEP mRNA:increased expression:lung RGD PMID:22305384 RGD:10395369 NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228 		JBrowse link
Gastric Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kit KIT proto-oncogene receptor tyrosine kinase IEP mRNA,protein:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kitlg KIT ligand IEP mRNA:decreased expression:stomach: RGD PMID:20040059 RGD:12911222 NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214 		JBrowse link
Intestinal Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IEP RGD PMID:15001561 RGD:13515113 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Agt angiotensinogen IEP protein:increased expression:plasma RGD PMID:15001561 RGD:13515113 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ahr aryl hydrocarbon receptor treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP RGD PMID:24232000 RGD:13792678 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23946597 RGD:13782356 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:23946597 RGD:13782356 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP mRNA:increased expression:small intestine RGD PMID:18475188 RGD:2307016 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Cd14 CD14 molecule IEP protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cldn1 claudin 1 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Cldn3 claudin 3 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001 		JBrowse link
G Cldn5 claudin 5 IEP protein:decreased expression:colon: RGD PMID:19929946 RGD:2325127 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Crp C-reactive protein IEP protein:increased expression:intestine: RGD PMID:17981193 RGD:5129536 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:9117128 RGD:11039476 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G F7 coagulation factor VII ISO human protein in a rat model RGD PMID:22920553 RGD:11041662 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29170412 RGD:13792603 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Gpt glutamic--pyruvic transaminase IEP protein:increased expression:serum RGD PMID:16557159 RGD:401717563 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Hmgb1 high mobility group box 1 IEP RGD PMID:22093738 RGD:10402181 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:19362701 RGD:10766423 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:11922743 RGD:11041790 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:12095141 PMID:22079846 RGD:11522715, RGD:401794136 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il6 interleukin 6 treatment IDA
IEP		 RGD PMID:11959089 PMID:22079846 RGD:11062110, RGD:401794136 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Jak2 Janus kinase 2 IMP RGD PMID:22777122 RGD:10403072 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Lbp lipopolysaccharide binding protein IEP protein:increased expression:heart, kidney, liver, lung RGD PMID:22493902 RGD:9685194 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Mbl2 mannose binding lectin 2 severity ISO DNA:polymorphisms:exon: RGD PMID:19477015 RGD:12910933 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mir155 microRNA 155 ISO miRNA:increased expression:Peyer's patch RGD PMID:30206757 RGD:21409753 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir21 microRNA 21 IEP RGD PMID:30309483 RGD:41410822 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IDA RGD PMID:16610051 RGD:7777112 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:28382390 RGD:13440093 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 disease_progression IEP mRNA:decreased expression:liver (rat) RGD PMID:23331901 RGD:15042883 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase treatment IMP RGD PMID:15791006 RGD:13514040 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A ISO mRNA:increased expression:jejunum (human) RGD PMID:20965186 RGD:9999150 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:15187522 RGD:11250409 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Serpinc1 serpin family C member 1 treatment IEP RGD PMID:21046505 RGD:11035258 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Serpine1 serpin family E member 1 IDA protein:increased activity:plasma (rat) RGD PMID:12717359 RGD:11081012 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 treatment IEP RGD PMID:27538408 RGD:151347179 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Tnf tumor necrosis factor treatment IEP RGD PMID:22079846 RGD:401794136 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Traf6 TNF receptor associated factor 6 IEP RGD PMID:27538408 RGD:151347179 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 ameliorates IDA associated with mesenteric vascular occlusion; RGD PMID:18091551 RGD:127284848 NCBI chr 9:12,763,819...12,779,285
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:plasma: RGD PMID:10365842 RGD:11080742 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:23010742 RGD:13209016 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Kidney Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme IMP RGD PMID:21680852 RGD:6893484 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 IEP mRNA:decreased expression:kidney RGD PMID:20528771 RGD:9685432 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Acvr2b activin A receptor type 2B treatment ISO human construct in rat model RGD PMID:27732750 RGD:329322881 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 treatment IEP RGD PMID:22015440 RGD:13703100 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adam2 ADAM metallopeptidase domain 2 IEP RGD PMID:11967014 RGD:10047130 NCBI chr15:40,242,651...40,284,025
Ensembl chr15:40,242,783...40,283,952 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP RGD PMID:18272597 RGD:9684850 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing treatment ISO RGD PMID:21412771 RGD:8695946 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin treatment IEP
ISO		 protein:increased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 ISO RGD PMID:31089212 RGD:27226686 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member ISO RGD PMID:22022451 RGD:7241603 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Anxa1 annexin A1 treatment IDA RGD PMID:20953576 RGD:7421585 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa5 annexin A5 ISO RGD PMID:21918686 RGD:7242028 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 treatment IEP RGD PMID:26362957 RGD:13703110 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Apoa1 apolipoprotein A1 treatment ISO RGD PMID:18535924 RGD:7241574 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Atm ATM serine/threonine kinase IEP protein:increased expression:kidney RGD PMID:22768306 RGD:10053607 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:23151253 RGD:10054101 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:18221257 PMID:29285062 RGD:2293026, RGD:13792599 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdkrb1 bradykinin receptor B1 ISO RGD PMID:18725957 RGD:7241559 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:26412257 RGD:11561958 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bmi1 BMI1 proto-oncogene, polycomb ring finger ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr17:81,332,175...81,341,625
Ensembl chr17:81,332,214...81,388,690 		JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP mRNA, protein:increased expression:kidney RGD PMID:23698117 RGD:11561968 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G C3 complement C3 treatment IEP RGD PMID:19691975 RGD:7411689 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Calca calcitonin-related polypeptide alpha IMP RGD PMID:19194162 RGD:7204479 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23151253 RGD:10054101 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 IEP RGD PMID:17596683 RGD:5684536 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 treatment ISO RGD PMID:22160777 RGD:7247742 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ameliorates
treatment		 ISO
IDA		 mRNA, protein:increased expression:kidney, lung, serum RGD PMID:24920753 PMID:20396927 PMID:18650485 RGD:329845564, RGD:4891433, RGD:11526113 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Cd14 CD14 molecule ISO mRNA,protein:increased expression:kidney RGD PMID:10966493 RGD:7204444 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd40 CD40 molecule treatment IMP RGD PMID:25993320 RGD:11251055 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cfb complement factor B ISO RGD PMID:16467447 PMID:12538716 RGD:7242709, RGD:7242734 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cfh complement factor H treatment IEP
ISO		 protein:decreased expression:serum: RGD PMID:20538296 PMID:20538296 RGD:7364948, RGD:7364948 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator ISO RGD PMID:14569092 RGD:7242896 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162 		JBrowse link
G Col1a1 collagen type I alpha 1 chain ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Csf1 colony stimulating factor 1 ISO mRNA:increased expression:kidney RGD PMID:23143303 PMID:19196448 RGD:7257565, RGD:7257570 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf1r colony stimulating factor 1 receptor ISO RGD PMID:23143303 RGD:7257565 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Ctla4 cytotoxic T-lymphocyte-associated protein 4 ISO RGD PMID:22189844 PMID:9407517 RGD:7204675, RGD:7204727 NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO RGD PMID:20038794 RGD:7257679 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IEP protein:increased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 treatment IMP RGD PMID:23552495 RGD:7244372 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Daxx death-domain associated protein ISO protein:increased expression:kidney: RGD PMID:18480747 PMID:18480747 RGD:9587836, RGD:9587836 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 ISO protein:increased expression:kidney (mouse) RGD PMID:31383731 RGD:151347540 NCBI chr20:3,042,494...3,064,442
Ensembl chr20:3,044,320...3,064,468 		JBrowse link
G Dhfr dihydrofolate reductase treatment IEP mRNA,protein:decreased expression:kidney: RGD PMID:18408363 RGD:11040540 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713 		JBrowse link
G Drd3 dopamine receptor D3 treatment IDA RGD PMID:25989500 RGD:13506961 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Eed embryonic ectoderm development ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 IEP mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 IEP mRNA, protein:decreased expression:kidney RGD PMID:19349364 RGD:11252083 NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:16980042 RGD:10450580 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Eng endoglin IEP
ISO		 mRNA, protein:increased expression:kidney (rat) RGD PMID:16751653 PMID:16751653 RGD:7248779, RGD:7248779 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Ep300 E1A binding protein p300 IEP protein:altered localization:kidney (rat) RGD PMID:23936185 RGD:7257563 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:19961832 PMID:25581532 RGD:10401077, RGD:11041698 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F3 coagulation factor III, tissue factor IEP protein:decreased expression:lung RGD PMID:25883098 RGD:11341735 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fas Fas cell surface death receptor treatment IEP RGD PMID:29285062 RGD:13792599 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand treatment IEP RGD PMID:29285062 RGD:13792599 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fcgr1a Fc gamma receptor 1A treatment ISO RGD PMID:22402584 RGD:9685699 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994 		JBrowse link
G Fga fibrinogen alpha chain IEP mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgb fibrinogen beta chain treatment IEP
ISO		 mRNA, protein:increased expression:kidney RGD PMID:21685370 PMID:21685370 RGD:7175292, RGD:7175292 NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 exacerbates
ameliorates		 ISO
IMP		 protein:increased phosphorylation:kidney (mouse) RGD PMID:20591940 PMID:22688984 PMID:29344510 PMID:32523960 RGD:155663667, RGD:155882537, RGD:155782904, RGD:155782882 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgg fibrinogen gamma chain IEP mRNA,protein:increased expression:kidney RGD PMID:21685370 RGD:7175292 NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322 		JBrowse link
G Fn1 fibronectin 1 IEP RGD PMID:11352844 RGD:7205629 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit ISO RGD PMID:19095962 RGD:7242184 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gfer growth factor, augmenter of liver regeneration treatment IEP
ISO		 protein:increased expression:kidney: RGD PMID:20332418 PMID:20332418 RGD:9685723, RGD:9685723 NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869 		JBrowse link
G Glo1 glyoxalase 1 IMP RGD PMID:19211689 RGD:7242566 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649 		JBrowse link
G Gpx3 glutathione peroxidase 3 IEP protein:decreased expression:kidney
mRNA:decreased expression:kidney		 RGD PMID:37033969 PMID:22442209 RGD:401827821, RGD:401827906 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24630969 RGD:10401866 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEP mRNA, protein:decreased expression:kidney RGD PMID:29137244 RGD:158014894 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 IEP protein:decreased expression:kidney RGD PMID:37033969 RGD:401827821 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G H2ax H2A.X variant histone treatment IEP RGD PMID:23726287 RGD:8693706 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Has1 hyaluronan synthase 1 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 1:58,693,411...58,705,653
Ensembl chr 1:58,693,411...58,705,397 		JBrowse link
G Has2 hyaluronan synthase 2 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 IEP
ISO		 protein:increased expression:urine: RGD PMID:23552495 PMID:23019274 PMID:23085062 RGD:7244372, RGD:7245495, RGD:7245489 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment
severity		 IDA
IMP		 RGD PMID:17519789 PMID:22432008 RGD:1626334, RGD:9068883 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP RGD PMID:21291499 RGD:10755580 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsf1 heat shock transcription factor 1 IEP protein:increased expression:kidney (rat) RGD PMID:23102208 RGD:10402775 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP RGD PMID:7569112 RGD:7242788 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hyal1 hyaluronidase 1 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 8:108,250,668...108,254,519
Ensembl chr 8:108,250,667...108,260,210 		JBrowse link
G Hyal2 hyaluronidase 2 IEP RGD PMID:22529164 RGD:9588636 NCBI chr 8:108,241,895...108,246,853
Ensembl chr 8:108,243,133...108,246,850 		JBrowse link
G Ifng interferon gamma treatment ISO RGD PMID:28355607 RGD:14975115 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IEP mRNA: increased expression: kidney: 3 and 5 days post ischemia RGD PMID:10990448 RGD:7242905 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IMP RGD PMID:19546526 RGD:7495779 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 treatment IDA
ISO		 RGD PMID:24079335 PMID:28664613 RGD:7364864, RGD:14975137 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il18 interleukin 18 treatment IMP RGD PMID:22089199 RGD:8655971 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta ameliorates IDA
ISO		 RGD PMID:20030532 PMID:24920753 RGD:7175501, RGD:329845564 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein
mouse model treated with human protein		 RGD PMID:18363573 PMID:9555664 PMID:16849996 RGD:6907101, RGD:6909149, RGD:6907359 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhbb inhibin subunit beta B IEP protein:increased expression:serum (rat) RGD PMID:27732750 RGD:329322881 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO
IMP		 Associated with renal transplant patients RGD PMID:20504838 PMID:11007822 RGD:6907049, RGD:6907073 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 IEP protein:decreased expression:kidney RGD PMID:21250976 RGD:7297045 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Kl Klotho treatment IEP
ISO		 mRNA,protein:decreased expression:renal tubule: RGD PMID:16204278 PMID:16204278 RGD:10403064, RGD:10403064 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO protein:increased expression:kidney (mouse) RGD PMID:31570196 RGD:155888490 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Lcn2 lipocalin 2 IEP
ISO		 protein:increased expression:urine:
mRNA,protein:increased expression:kidney,urine
mRNA,protein:increased expression:kidney:		 RGD PMID:23364806 PMID:27800610 PMID:20181666 PMID:23085062 RGD:7245469, RGD:126790572, RGD:126779563, RGD:7245489 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lep leptin resistance IDA RGD PMID:22969992 RGD:6909133 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lgals3 galectin 3 IEP mRNA:increased expression:kidney RGD PMID:10980121 RGD:9685228 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment ISO
IEP		 RGD PMID:20075199 PMID:26412257 RGD:11561916, RGD:11561958 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IMP RGD PMID:23952292 RGD:10412647 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mc1r melanocortin 1 receptor IEP protein:decreased expression:kidney outer medulla RGD PMID:18790174 RGD:5687322 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mir146a microRNA 146a treatment IEP RGD PMID:27760486 RGD:155882556 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir320a microRNA 320a treatment IEP RGD PMID:31089916 PMID:27760486 RGD:155882543, RGD:155882556 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473 		JBrowse link
G Mir381 microRNA 381 IEP RNA:decreased expression:kidney RGD PMID:29073721 RGD:13825150 NCBI chr 6:128,740,976...128,741,036 JBrowse link
G Mir423 microRNA 423 treatment IMP RGD PMID:29137244 RGD:158014894 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226 		JBrowse link
G Mir494 microRNA 494 ameliorates ISO RGD PMID:23160513 RGD:155883172 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mpo myeloperoxidase IEP
ISO		 protein:increased activity:kidney RGD PMID:22950848 PMID:18055546 RGD:6909167, RGD:7174699 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Muc1 mucin 1, cell surface associated treatment IDA RGD PMID:22019164 RGD:7245959 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP mRNA:increased expression:kidney (rat) RGD PMID:17220792 RGD:7207777 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 IEP
ISO		 RGD PMID:24096033 PMID:22160772 RGD:13801197, RGD:13801199 NCBI chr 1:243,408,656...243,413,715
Ensembl chr 1:243,408,619...243,413,817 		JBrowse link
G Nes nestin IEP RGD PMID:24503548 RGD:11570523 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IEP RGD PMID:31089916 RGD:155882543 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos2 nitric oxide synthase 2 treatment IEP RGD PMID:18408363 RGD:11040540 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP RGD PMID:29291552 PMID:18408363 RGD:13504682, RGD:11040540 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox1 NADPH oxidase 1 treatment IEP RGD PMID:34244746 RGD:329955363 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nppa natriuretic peptide A ISO RGD PMID:20471588 RGD:7247717 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:21545725 RGD:11035217 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 severity ISO mRNA:increased expression:kidney RGD PMID:22343121 PMID:22343121 RGD:14700869, RGD:14700869 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP RGD PMID:12531391 RGD:2317150 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Pax2 paired box 2 IEP mRNA, protein:increased expression:kidney RGD PMID:12444203 RGD:727468 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Pdgfb platelet derived growth factor subunit B IEP mRNA,protein:increased expression:tubule, S3 segment: RGD PMID:10550325 RGD:8554477 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha IEP mRNA:increased expression:kidney RGD PMID:10550325 RGD:8554477 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta IMP
IEP		 mRNA:increased expression:kidney RGD PMID:12819032 PMID:10550325 RGD:1580850, RGD:8554477 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Peg10 paternally expressed 10 ISO mRNA:increased expression:kidney (mouse) RGD PMID:16778176 RGD:401851077 NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel IEP protein:increased expression:kidney (rat) RGD PMID:12454224 RGD:1580868 NCBI chr14:5,237,135...5,280,455
Ensembl chr14:5,237,135...5,280,825 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment IDA RGD PMID:24918615 RGD:10059636 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ptgis prostaglandin I2 synthase ISO mRNA:increased expression:kidney (mouse) RGD PMID:30413885 RGD:401959745 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO mRNA,protein:decreased expression:kidney,plasma: RGD PMID:23393318 PMID:23393318 RGD:7327166, RGD:7327166 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G Serpina1 serpin family A member 1 treatment ISO RGD PMID:28235038 RGD:14695051 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339 		JBrowse link
G Serpinc1 serpin family C member 1 severity IMP RGD PMID:26108065 PMID:26108065 RGD:11354006, RGD:11354006 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Serpinc1em2Mcwi serpin family C member 1; ZFN induced mutant 2, Medical College of Wisconsin IMP RGD PMID:26108065 RGD:11354006
G Serpine1 serpin family E member 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO mRNA, protein:increased expression:kidney RGD PMID:24744439 RGD:12859042 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:22324445 RGD:9495930 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Six2 SIX homeobox 2 ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193 		JBrowse link
G Slc22a1 solute carrier family 22 member 1 IEP RGD PMID:21835768 RGD:7243877 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 IEP RGD PMID:21835768 RGD:7243877 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP protein:decreased expression:renal proximal tubule, brush border membrane (rat) RGD PMID:15775707 RGD:2311304 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IEP RGD PMID:12819032 RGD:1580850 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 severity ISO RGD PMID:12709397 RGD:7244143 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr10:64,967,035...65,012,916
Ensembl chr10:64,966,967...65,012,738 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:11796005 RGD:11062062 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tlr2 toll-like receptor 2 treatment
severity		 IDA
ISO		 RGD PMID:23239000 PMID:11801667 PMID:20130923 PMID:22750071 PMID:23023072 RGD:7207892, RGD:7241087, RGD:7240552, RGD:7207896, RGD:7207894 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 treatment IDA
ISO		 RGD PMID:23239000 PMID:11801667 PMID:20130923 RGD:7207892, RGD:7241087, RGD:7240552 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor ameliorates IEP
ISO		 protein:increased expression:serum RGD PMID:19925291 PMID:24920753 RGD:2315112, RGD:329845564 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO mRNA:increased expression:lung RGD PMID:22728466 RGD:7245543 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP protein:increased expression:kidney RGD PMID:20164827 RGD:7240507 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vwf von Willebrand factor IEP protein:increased expression:serum: RGD PMID:12684225 RGD:11080744 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wt1 WT1 transcription factor ISO mRNA:altered expression:kidney (mouse) RGD PMID:18467665 RGD:155631277 NCBI chr 3:91,566,540...91,613,653
Ensembl chr 3:91,567,001...91,613,643 		JBrowse link
G Xdh xanthine dehydrogenase treatment IMP associated with Diabetes Mellitus, Type 2 RGD PMID:22995295 PMID:20616412 RGD:7247637, RGD:7247695 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Zfp667 zinc finger protein 667 ameliorates ISO RGD PMID:24920753 RGD:329845564 NCBI chr 1:67,601,803...67,622,041
Ensembl chr 1:67,601,807...67,622,041 		JBrowse link
limb reperfusion injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:36495512 RGD:401717522 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
Liver Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing treatment IDA RGD PMID:23762489 RGD:8695935 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin treatment IEP
ISO		 mRNA,protein:increased expression:liver,plasma: RGD PMID:19212187 PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP mRNA:increased expression:liver RGD PMID:21431875 RGD:10402078 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member treatment ISO
IEP		 protein:altered expression:liver (mouse)
protein:altered expression:liver (rat)		 RGD PMID:30671488 PMID:29589772 RGD:15036807, RGD:14975297 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Atf6 activating transcription factor 6 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atg13 autophagy related 13 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043 		JBrowse link
G Atg16l1 autophagy related 16-like 1 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529 		JBrowse link
G Atg4d autophagy related 4D, cysteine peptidase ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 8:19,807,733...19,817,321
Ensembl chr 8:19,807,766...19,817,321 		JBrowse link
G Atg7 autophagy related 7 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease		 RGD PMID:22647552 PMID:22847887 RGD:10053673, RGD:10053710 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ameliorates
treatment		 IEP
ISO		 mRNA:increased expression:liver
associated with Non-alcoholic Fatty Liver Disease		 RGD PMID:22647552 PMID:34144219 PMID:21092002 PMID:22847887 RGD:10053673, RGD:329812011, RGD:5134995, RGD:10053710 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment
ameliorates		 IDA
ISO
IEP		 associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887 PMID:34144219 PMID:21092002 RGD:10053710, RGD:329812011, RGD:5134995 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IEP associated with Non-alcoholic Fatty Liver Disease RGD PMID:22847887 RGD:10053710 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Becn1 beclin 1 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G C3 complement C3 treatment IEP RGD PMID:19854450 RGD:11040888 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Casp12 caspase 12 treatment IEP RGD PMID:29428101 RGD:13782166 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 treatment IEP
ISO		 RGD PMID:23423194 PMID:15300206 RGD:8661760, RGD:14695087 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 treatment
ameliorates		 IEP
ISO		 RGD PMID:23364428 PMID:34144219 RGD:13782358, RGD:329812011 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 ameliorates
treatment
severity		 IEP
ISO		 mRNA, protein:increased expression:liver, serum (rat) RGD PMID:9500701 PMID:34400126 PMID:10630515 PMID:27229110 RGD:8549627, RGD:329902072, RGD:14995929, RGD:14995460 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 treatment
severity		 ISO RGD PMID:28623253 PMID:28623253 RGD:14995305, RGD:14995305 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccn1 cellular communication network factor 1 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Ccr1 C-C motif chemokine receptor 1 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Ccr2 C-C motif chemokine receptor 2 severity ISO RGD PMID:27229110 RGD:14995460 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd14 CD14 molecule IDA RGD PMID:22564590 RGD:7183676 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd40 CD40 molecule treatment IMP RGD PMID:14741776 RGD:8547795 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cfh complement factor H treatment IEP
ISO		 mRNA,protein:decreased expression:liver,plasma: RGD PMID:19212187 PMID:19212187 RGD:7364958, RGD:7364958 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cs citrate synthase IDA RGD PMID:25416448 RGD:13504849 NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421 		JBrowse link
G Cst3 cystatin C ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 treatment
ameliorates		 IDA
ISO		 RGD PMID:21092002 PMID:34400126 RGD:5134995, RGD:329902072 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 treatment
ameliorates		 ISO RGD PMID:18041715 PMID:34400126 RGD:27095942, RGD:329902072 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 IEP mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ameliorates ISO RGD PMID:34144219 RGD:329812011 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Elane elastase, neutrophil expressed IMP RGD PMID:10588515 RGD:10450560 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:25769561 RGD:15090809 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Epor erythropoietin receptor IEP protein:increased phosphorylation:liver: RGD PMID:25769561 RGD:15090809 NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257 		JBrowse link
G F3 coagulation factor III, tissue factor treatment IMP RGD PMID:11750579 RGD:11341708 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fadd Fas associated via death domain treatment IEP RGD PMID:23423194 RGD:8661760 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor treatment IMP
IEP		 protein:increased expression:liver RGD PMID:17235585 PMID:18561025 PMID:16222447 RGD:2290283, RGD:14700680, RGD:1600351 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand treatment IMP RGD PMID:18561025 RGD:14700680 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fga fibrinogen alpha chain IEP mRNA:increased expression:liver (rat) RGD PMID:23503399 RGD:9685021 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fn1 fibronectin 1 IDA RGD PMID:12651615 RGD:7205470 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:22564598 PMID:13678701 RGD:329970282, RGD:329970285 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA associated with nonalcoholic fatty liver disease RGD PMID:28807209 RGD:13792730 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 IEP mRNA:decreased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G H2ax H2A.X variant histone treatment IEP RGD PMID:23792534 RGD:8693718 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IMP
IEP		 protein:increased oxidation:liver
mRNA, protein:increased expression, altered localization:serum, hepatocyte, cytoplasm		 RGD PMID:24578610 PMID:22514737 PMID:21431875 RGD:10402068, RGD:10402175, RGD:10402078 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IEP RGD PMID:20446775 RGD:10755725 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hp haptoglobin treatment IEP RGD PMID:17187421 PMID:21699906 RGD:1626366, RGD:11041815 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IMP
IEP		 associated with Intestinal Reperfusion Injury;protein:increased expression:liver RGD PMID:7884306 PMID:8780571 RGD:11520784, RGD:14402044 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 severity ISO RGD PMID:28938192 RGD:14985248 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma treatment IDA RGD PMID:22381173 RGD:12791280 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:21911118 RGD:7364839 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il18 interleukin 18 treatment IEP
ISO		 RGD PMID:25919765 PMID:14999688 RGD:14696667, RGD:14696668 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18bp interleukin 18 binding protein IEP mRNA,protein:increased expression:liver RGD PMID:25919765 RGD:14696667 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963 		JBrowse link
G Il1a interleukin 1 alpha treatment IEP
IDA		 mRNA:increased expression:lung
protein:increased expression:serum		 RGD PMID:19595018 PMID:9840148 PMID:19283466 RGD:2314952, RGD:11059517, RGD:6907377 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta ameliorates
treatment		 IDA
ISO		 associated with Cholestasis RGD PMID:21468628 PMID:34400126 PMID:32155285 RGD:7175318, RGD:329902072, RGD:155260323 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment ISO
IMP		 rat model treated with human protein RGD PMID:9000676 PMID:12451245 RGD:6909138, RGD:8551710 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 treatment
ameliorates		 IDA
ISO		 RGD PMID:24752458 PMID:34400126 PMID:34144219 PMID:32155285 RGD:11062134, RGD:329902072, RGD:329812011, RGD:155260323 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irf8 interferon regulatory factor 8 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Itgam integrin subunit alpha M treatment
exacerbates		 IMP
IEP		 protein:increased expression:neutrophil (rat) RGD PMID:8387952 PMID:11447039 RGD:329901847, RGD:329901849 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Jak2 Janus kinase 2 treatment IDA RGD PMID:22288937 RGD:10403073 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
G Lbp lipopolysaccharide binding protein IEP mRNA, protein:increased expression:liver RGD PMID:12134092 RGD:9685192 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ameliorates
exacerbates		 ISO protein:increased phosphorylation:liver (mouse) RGD PMID:30076625 PMID:30622220 RGD:155804280, RGD:155882441 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 IEP protein:increased activity:liver: RGD PMID:11679968 RGD:10412680 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mfn2 mitofusin 2 treatment IEP mRNA, protein:decreased expression:liver (rat) RGD PMID:27363631 PMID:24898700 RGD:12910833, RGD:13204829 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir145 microRNA 145 IEP mRNA:decreased expression:small intestine (rat) RGD PMID:23166305 RGD:155230822 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir155 microRNA 155 ISO RGD PMID:28640790 RGD:21079442 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir21 microRNA 21 IEP RNA:increased expression:liver RGD PMID:29187695 RGD:41410824 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir210 microRNA 210 treatment ISO RGD PMID:32155285 RGD:155260323 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir223 microRNA 223 ISO RNA:increased expression:liver
RNA:increased expression:serum,liver		 RGD PMID:19104939 PMID:28646120 RGD:13831297, RGD:21408574 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir34a microRNA 34a IEP miRNA:increased expression:liver RGD PMID:28963950 RGD:14695005 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mmp15 matrix metallopeptidase 15 IEP mRNA:increased expression:lung RGD PMID:19595018 RGD:2314952 NCBI chr19:9,663,449...9,684,943
Ensembl chr19:9,663,449...9,684,943 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment IEP associated with Fatty Liver;mRNA, protein:decreased expression, decreased activity:liver RGD PMID:17255325 RGD:8547976 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Muc1 mucin 1, cell surface associated IEP mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Muc3 mucin 3 IEP mRNA, protein:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr12:19,527,251...19,536,924
Ensembl chr12:19,527,321...19,538,522 		JBrowse link
G Muc4 mucin 4, cell surface associated IEP mRNA:decreased expression:bile duct RGD PMID:21775928 RGD:7364757 NCBI chr11:68,008,245...68,053,242 JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 ISO mRNA,protein:increased expression:liver: RGD PMID:36092961 RGD:268357360 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IEP RGD PMID:22288937 PMID:31952110 RGD:10403073, RGD:21201304 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP RGD PMID:28966130 RGD:13450941 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pf4 platelet factor 4 exacerbates ISO RGD PMID:25440775 RGD:329901829 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:12605111 PMID:18507760 RGD:11100021, RGD:11100046 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Rab10 RAB10, member RAS oncogene family ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193 		JBrowse link
G Rab8b RAB8B, member RAS oncogene family ameliorates ISO RGD PMID:34400126 RGD:329902072 NCBI chr 8:67,458,921...67,536,466
Ensembl chr 8:67,458,923...67,536,384 		JBrowse link
G Selplg selectin P ligand ameliorates IMP RGD PMID:16365457 RGD:401717523 NCBI chr12:42,796,690...42,809,908
Ensembl chr12:42,796,580...42,812,585 		JBrowse link
G Serpinc1 serpin family C member 1 treatment IEP
ISO		 RGD PMID:24726586 PMID:8589354 RGD:10450597, RGD:11038771 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Serpine1 serpin family E member 1 IEP protein:increased activity:plasma (rat) RGD PMID:12353078 RGD:8547901 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:16367929 RGD:1580273 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Sirt1 sirtuin 1 treatment IEP RGD PMID:24557422 RGD:9497542 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor IEP RGD PMID:19595018 RGD:2314952 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human gene in a rat model RGD PMID:16555330 PMID:11779401 RGD:8655889, RGD:1581095 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod3 superoxide dismutase 3 treatment ISO human gene in a rat model RGD PMID:11779401 RGD:1581095 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Tert telomerase reverse transcriptase treatment ISO RGD PMID:19545665 RGD:11038676 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tfpi tissue factor pathway inhibitor ISO RGD PMID:9921794 RGD:11062061 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tlr2 toll-like receptor 2 treatment ISO
IEP		 RGD PMID:16038046 PMID:25769561 RGD:15090805, RGD:15090809 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 treatment
severity		 IEP
ISO		 mRNA:increased expression:liver
protein:increased expression:membrane raft:		 RGD PMID:21431875 PMID:21693218 PMID:22797797 PMID:23395256 PMID:27064547 RGD:10402078, RGD:5685379, RGD:14697702, RGD:14697699, RGD:14697698 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor treatment IEP
ISO
IMP		 protein:increased expression:serum (rat) RGD PMID:24726586 PMID:32155285 PMID:11592783 PMID:19357028 PMID:11129814 More... RGD:10450597, RGD:155260323, RGD:2325259, RGD:15039406, RGD:14995473, RGD:14995447, RGD:14985258, RGD:14985257, RGD:14696803 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A IEP protein:increased localization:mitochondrion RGD PMID:23423194 RGD:8661760 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tradd TNFRSF1A-associated via death domain treatment IEP RGD PMID:23423194 RGD:8661760 NCBI chr19:33,136,148...33,142,714
Ensembl chr19:33,136,138...33,142,638 		JBrowse link
G Ucp2 uncoupling protein 2 IEP mRNA:increased expression:liver RGD PMID:22195248 RGD:7175309 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Vegfa vascular endothelial growth factor A IEP RGD PMID:26451003 RGD:15036791 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xdh xanthine dehydrogenase treatment IEP RGD PMID:24768926 RGD:13209011 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Lung Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator treatment
ameliorates		 IEP
ISO		 RGD PMID:23953793 PMID:34238924 RGD:10054119, RGD:153350155 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 treatment IEP RGD PMID:23953793 RGD:10054119 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Col1a1 collagen type I alpha 1 chain ISO mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col3a1 collagen type III alpha 1 chain ISO mRNA:increased expression:lung (mouse) RGD PMID:34238924 RGD:153350155 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Crebbp CREB binding protein ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Egr1 early growth response 1 treatment IMP
IEP		 RGD PMID:22878149 PMID:23232597 RGD:10395282, RGD:10395299 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:17888675 RGD:10450582 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO mRNA:increased expression:lung (rat) RGD PMID:35600952 RGD:155663563 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Hmgb1 high mobility group box 1 IEP protein:increased expression:lung RGD PMID:22115333 RGD:10402095 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 IEP protein:increased expression:lung RGD PMID:21227458 RGD:10755577 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il1b interleukin 1 beta ameliorates IDA
ISO
IEP		 protein:increased expression:lung (rat) RGD PMID:23142117 PMID:34238924 PMID:23122581 RGD:7183185, RGD:153350155, RGD:7204125 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il4 interleukin 4 treatment IDA RGD PMID:24365768 RGD:10402797 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ameliorates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP protein:increased activity:lung RGD PMID:18694576 RGD:5129703 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor treatment IEP RGD PMID:22503847 RGD:7240537 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nos3 nitric oxide synthase 3 IMP
ISO		 mRNA:increased expression:lung (mouse) RGD PMID:20815765 PMID:25382268 RGD:4892012, RGD:11533932 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:21781312 RGD:6771212 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IDA
IEP		 protein:increased expression:alveolar macrophage (rat) RGD PMID:21781312 PMID:16449942 RGD:6771212, RGD:11541083 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:19782612 RGD:11100035 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Serpine1 serpin family E member 1 treatment ISO
IDA		 protein:increased expression:plasma (human) RGD PMID:17846288 PMID:11606484 RGD:8547720, RGD:11080966 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Tlr4 toll-like receptor 4 treatment IEP RGD PMID:22115333 RGD:10402095 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor ameliorates IMP
ISO		 RGD PMID:17294835 PMID:34238924 RGD:4143397, RGD:153350155 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Zfp36 zinc finger protein 36 exacerbates ISO RGD PMID:34238924 RGD:153350155 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564 		JBrowse link
Myocardial Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18316485 RGD:2301903 NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Acvr2b activin A receptor type 2B treatment ISO human construct in mouse model
mRNA, protein:decreased expression:heart (mouse)		 RGD PMID:30765322 PMID:30765322 RGD:329849112, RGD:329849112 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Ada adenosine deaminase IDA protein:increased expression RGD PMID:16641873 RGD:1624305 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO CTD Direct Evidence: therapeutic CTD PMID:16155579 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adrb1 adrenoceptor beta 1 IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10900253 PMID:17201736 RGD:5129149 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 IDA RGD PMID:16269402 RGD:1598746 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP protein:increased expression:heart (rat) RGD PMID:16505177 RGD:1625342 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agl amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase IMP RGD PMID:9281456 RGD:1598779 NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828 		JBrowse link
G Agt angiotensinogen ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:2535056 PMID:19166939 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a IEP protein:increased expression:myocardium RGD PMID:21078800 RGD:5129194 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ahr aryl hydrocarbon receptor treatment IMP RGD PMID:35788946 RGD:401793705 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP
ISO		 protein:decreased expression:mitochondrion: RGD PMID:23685150 PMID:23685150 RGD:10053560, RGD:10053560 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 IDA protein:increased phosphorylation:heart left ventricle RGD PMID:20217242 RGD:5509104 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 IDA RGD PMID:16418318 RGD:2313347 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Alb albumin ISO CTD Direct Evidence: marker/mechanism CTD PMID:9572063 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member IDA RGD PMID:23468836 RGD:7241598 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase IMP RGD PMID:20011686 RGD:2317527 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Angpt2 angiopoietin 2 IEP mRNA, protein:increased expression:myocardium (rat) RGD PMID:12737621 RGD:1601505 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Ank1 ankyrin 1 IDA RGD PMID:9378703 RGD:1599110 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Ank2 ankyrin 2 IDA RGD PMID:9378703 RGD:1599110 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 IEP protein:decreased expression:myocardium RGD PMID:19299913 RGD:5133278 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Anxa1 annexin A1 treatment IEP
ISO		 protein:increased expression:heart, leukocyte RGD PMID:11641252 PMID:22924634 PMID:22924634 RGD:2306910, RGD:7421655, RGD:7421655 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP protein:altered localization:cytoplasm RGD PMID:17602955 RGD:2315672 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Arrb2 arrestin, beta 2 IEP RGD PMID:29016703 RGD:13506827 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Atf3 activating transcription factor 3 IEP RGD PMID:11485922 RGD:7327201 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 ISO CTD Direct Evidence: therapeutic CTD PMID:29702141 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 IMP RGD PMID:17630344 RGD:13782075 NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10734148 PMID:28637456 RGD:13782080 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta treatment IEP protein:decreased expression:myocardium (rat) RGD PMID:26109848 PMID:25305180 RGD:13792666, RGD:13792676 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment IEP
IDA		 protein:increased expression, decreased serine phosphorylation:heart RGD PMID:15339931 PMID:23364609 RGD:2292700, RGD:10053674 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20026869 PMID:21223820 PMID:25547710 PMID:31583047 RGD:10054103, RGD:13782178, RGD:155230831 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
IDA		 RGD PMID:16289365 PMID:23364609 PMID:20821058 PMID:31583047 RGD:1599484, RGD:10053674, RGD:11561911, RGD:155230831 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IDA RGD PMID:12668130 RGD:11035287 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Becn1 beclin 1 treatment IDA
ISO		 RGD PMID:20821058 PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bid BH3 interacting domain death agonist IDA
IEP		 protein:increased cleavage:heart: RGD PMID:19940077 PMID:11934844 RGD:2317561, RGD:13782263 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Blk BLK proto-oncogene, Src family tyrosine kinase IEP mRNA:increased expression:left ventricle (rat) RGD PMID:17562528 RGD:1642307 NCBI chr15:37,626,746...37,665,053
Ensembl chr15:37,627,039...37,665,031 		JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment IMP
IEP		 protein:decreased expression:myocardium (human) RGD PMID:16645637 PMID:28661226 RGD:11561983, RGD:155260328 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Brd4 bromodomain containing 4 ISO mRNA,protein:increased expression:heart RGD PMID:33982231 RGD:155883171 NCBI chr 7:11,216,446...11,296,029
Ensembl chr 7:11,216,446...11,295,539 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 IEP mRNA:increased expression:heart RGD PMID:12909328 RGD:2289075 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G C3 complement C3 IEP protein:increased expression:myocardium RGD PMID:11560858 RGD:1582136 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C5 complement C5 treatment IDA
IMP		 RGD PMID:9631876 PMID:23067403 RGD:1600666, RGD:7411626 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G Casp1 caspase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp12 caspase 12 treatment IEP
ISO		 protein:increased activity:myocardium
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:14998631 PMID:19406177 PMID:25547710 RGD:2311458, RGD:13782178 NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 treatment
ameliorates		 IMP
ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:18470603 PMID:29538428 PMID:30259997 RGD:2293314, RGD:13782276, RGD:329337366 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:29538428 RGD:13782276 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte 		CTD
RGD		 PMID:14998631 PMID:11934844 RGD:13782263 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 treatment
ameliorates		 ISO
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased activity:cardiomyocyte,endothelial cell		 CTD
RGD		 PMID:14998631 PMID:11934844 PMID:29538428 PMID:30259997 RGD:13782263, RGD:13782276, RGD:329337366 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Casr calcium-sensing receptor IEP protein:increased expression:ventricular myocardium (rat) RGD PMID:21766206 RGD:7205698 NCBI chr11:64,235,251...64,304,811
Ensembl chr11:64,235,251...64,304,811 		JBrowse link
G Cast calpastatin ameliorates IEP
ISO		 human transcript overexpression in rat model RGD PMID:12482022 PMID:14519437 RGD:5683872, RGD:405101692 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase IEP
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:21600015 PMID:11510883 RGD:1581149 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbl Cbl proto-oncogene severity ISO RGD PMID:24583314 RGD:11251947 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 IEP
ISO		 mRNA:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12087064 PMID:10908159 RGD:8549625 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 ISO protein:decreased expression:monocyte: RGD PMID:15786508 RGD:4892017 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 treatment ISO
IEP		 protein:decreased expression:blood, monocyte (human) RGD PMID:15786508 PMID:23456481 RGD:4892017, RGD:8552227 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator treatment IEP RGD PMID:18466417 RGD:11341714 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:18771032 RGD:2316217 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 IMP RGD PMID:17950273 RGD:2316224 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Cobll1 cordon-bleu WH2 repeat protein-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34355838 NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194 		JBrowse link
G Crebbp CREB binding protein treatment IEP RGD PMID:24338162 RGD:153352322 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crp C-reactive protein IEP protein:increased expression:serum RGD PMID:21122204 RGD:5128547 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 ISO protein:decreased expression:blood, monocyte RGD PMID:15786508 RGD:4892017 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 IMP RGD PMID:11342480 RGD:5135269 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cybb cytochrome b-245 beta chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:19207477 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:14998631 NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dnm1l dynamin 1-like ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP
IEP		 RGD PMID:18586023 PMID:12193087 RGD:4892580, RGD:7244160 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15642760 PMID:16700825 PMID:18586023 RGD:4892580 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednra endothelin receptor type A IMP RGD PMID:18586023 RGD:4892580 NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049 		JBrowse link
G Ednrb endothelin receptor type B IMP RGD PMID:21048781 RGD:4892332 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 susceptibility ISO RGD PMID:20185832 RGD:11251775 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Ephx2 epoxide hydrolase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19834332 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615 		JBrowse link
G Esr1 estrogen receptor 1 IMP RGD PMID:18314151 RGD:4892299 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 ISO RGD PMID:18656630 RGD:5508820 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Fadd Fas associated via death domain treatment ISO
IEP		 RGD PMID:26038570 PMID:26948086 RGD:11341801, RGD:13792504 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor treatment IDA RGD PMID:21316771 RGD:8686424 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fis1 fission, mitochondrial 1 ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:27129213 RGD:11574725 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gcg glucagon treatment ISO RGD PMID:24125539 RGD:10402369 NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929 		JBrowse link
G Gdf11 growth differentiation factor 11 ISO mRNA, protein:decreased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725 		JBrowse link
G Gja1 gap junction protein, alpha 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17445419 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Glrx glutaredoxin IEP mRNA:decreased expression:heart: RGD PMID:18163565 RGD:2306160 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO RGD PMID:11043918 RGD:401827843 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 treatment
susceptibility
severity		 IMP
ISO
IDA		 associated with Diabetes Mellitus, Experimental
associated with Hypertension
protein:increased expression:heart, mitochondrion (mouse)		 RGD PMID:27865836 PMID:27601479 PMID:27296507 PMID:24170934 PMID:23467820 RGD:13513990, RGD:13513993, RGD:13513995, RGD:13792704, RGD:13792779 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA
IEP		 RGD PMID:20217242 PMID:29978610 PMID:26918336 RGD:5509104, RGD:13792725, RGD:13792772 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IEP RGD PMID:24769323 RGD:10401892 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates ISO RGD PMID:31284127 RGD:158013771 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:23108649 RGD:8693739 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hdac3 histone deacetylase 3 ameliorates ISO RGD PMID:33982231 RGD:155883171 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP
IDA
ISO		 mRNA:increased expression:heart
protein:increased expression:myocardium
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18549825 PMID:22050707 PMID:12189448 PMID:19727523 PMID:20170615 RGD:1626327, RGD:5147885, RGD:9068872 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 treatment IEP
IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21113057 PMID:23531454 PMID:19540007 RGD:10402066, RGD:10402170 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IDA
IEP
ISO		 RGD PMID:12709584 PMID:22179023 PMID:23921302 RGD:1598392, RGD:10755573, RGD:10755585 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hrh2 histamine receptor H 2 susceptibility ISO RGD PMID:23467745 RGD:9685524 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:15076218 RGD:1626433 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Hsf1 heat shock transcription factor 1 ISO RGD PMID:22426029 RGD:10402789 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A treatment IEP RGD PMID:20501665 RGD:10003160 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP RGD PMID:24129401 PMID:25547710 RGD:11354962, RGD:13782178 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Htra2 HtrA serine peptidase 2 ISO protein:increased expression:myocardium, cytosol (mouse) RGD PMID:15611365 RGD:5688376 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP
ISO		 protein:increased expression:heart (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12087064 PMID:20851484 RGD:4145348 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il10 interleukin 10 treatment IEP
IDA		 protein:increased expression:plasma RGD PMID:19275881 PMID:23840272 RGD:2311056, RGD:7365001 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il17a interleukin 17A treatment IMP RGD PMID:22030025 RGD:9068944 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 ISO
IDA		 RGD PMID:19164288 PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il18bp interleukin 18 binding protein ISO mRNA:increased expression:heart RGD PMID:19164288 PMID:19805173 RGD:4889578, RGD:4889400 NCBI chr 1:156,372,923...156,374,963
Ensembl chr 1:156,372,883...156,374,963 		JBrowse link
G Il18rap interleukin 18 receptor accessory protein ISO RGD PMID:19164288 RGD:4889578 NCBI chr 9:42,768,112...42,800,964
Ensembl chr 9:42,768,220...42,800,959 		JBrowse link
G Il1a interleukin 1 alpha treatment ISO
IEP		 RGD PMID:8576926 PMID:7622355 RGD:7794741, RGD:7794764 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta treatment IEP mRNA:increased expression:heart RGD PMID:17134725 PMID:31583047 RGD:1626628, RGD:155230831 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl2 interleukin 1 receptor-like 2 IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167 NCBI chr 9:42,591,658...42,639,351
Ensembl chr 9:42,591,934...42,636,667 		JBrowse link
G Il1rl2tm1(Myh6-cre)Mhzh interleukin 1 receptor-like 2; tm1 (Myh6-cre), Mhzh IMP compared to Wild Type in cardiopulmonary bypass model RGD PMID:32048631 RGD:126925167
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:22649318 RGD:7174360 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il36rn interleukin 36 receptor antagonist IMP RGD PMID:32048631 RGD:126925167 NCBI chr 3:7,044,419...7,051,016
Ensembl chr 3:7,044,406...7,051,016 		JBrowse link
G Il36rntm1(Myh6-cre)Mhzh interleukin 36 receptor antagonist; tm1, Mhzh IMP RGD PMID:32048631 RGD:126925167
G Il6 interleukin 6 treatment IDA
IEP		 RGD PMID:27087891 PMID:31583047 RGD:11062149, RGD:155230831 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6r interleukin 6 receptor ISO RGD PMID:16056242 RGD:1625435 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536 		JBrowse link
G Inhba inhibin subunit beta A ISO mRNA, protein:increased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 IEP protein:increased activity:ventricle myocardium (rat) RGD PMID:15793310 RGD:1579809 NCBI chr  X:151,768,621...151,778,521
Ensembl chr  X:151,768,777...151,778,521 		JBrowse link
G Irf9 interferon regulatory factor 9 ameliorates
exacerbates		 ISO protein:increased expression:left ventricular free wall RGD PMID:25150882 PMID:25150882 PMID:25150882 RGD:125093742, RGD:125093742, RGD:125093742 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236 		JBrowse link
G Jak2 Janus kinase 2 treatment IMP associated with Diabetes Mellitus, Experimental RGD PMID:23796350 PMID:23747931 RGD:8694332, RGD:10403071 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kcnj11 potassium inwardly-rectifying channel, subfamily J, member 11 ISO RGD PMID:17906066 RGD:7297046 NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 IDA RGD PMID:12234964 RGD:729109 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 treatment IMP RGD PMID:23953572 RGD:9685183 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Kng1 kininogen 1 ISO CTD Direct Evidence: therapeutic CTD PMID:2535056 PMID:7856280 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Lep leptin IEP RGD PMID:21122204 RGD:5128547 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lepr leptin receptor IEP mRNA:decreased expression:heart
mRNA:altered expression:heart		 RGD PMID:15284063 PMID:17134725 RGD:5129123, RGD:1626628 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908 		JBrowse link
G Lum lumican IDA RGD PMID:11348051 RGD:1582122 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP
ISO		 protein:increased expression:heart RGD PMID:20821058 PMID:20812860 RGD:11561911, RGD:11561944 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 ISO RGD PMID:14749328 PMID:15492008 RGD:7495840, RGD:1582277 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IEP RGD PMID:31583047 RGD:155230831 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IDA RGD PMID:15653762 PMID:25345742 RGD:1582282, RGD:13800900 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 ISO RGD PMID:14749328 RGD:7495840 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IEP
IDA		 RGD PMID:29741915 PMID:28814571 PMID:25345742 RGD:13800564, RGD:13800874, RGD:13800900 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 treatment IDA
IEP		 RGD PMID:15309413 PMID:12883833 PMID:31583047 RGD:1582311, RGD:1582312, RGD:155230831 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mb myoglobin ISO
IDA		 RGD PMID:15132981 PMID:11972171 RGD:1582385, RGD:1582431 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mbl1 mannose binding lectin 1 IDA
ISO
IMP		 RGD PMID:11560858 PMID:15972690 PMID:20216929 RGD:1582136, RGD:1582131, RGD:4889154 NCBI chr16:17,029,146...17,035,187
Ensembl chr16:17,029,118...17,035,174 		JBrowse link
G Mbl2 mannose binding lectin 2 treatment ISO RGD PMID:25482922 RGD:11530049 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mdm2 MDM2 proto-oncogene IEP protein:increased serine phosphorylation:heart ventricle (rat) RGD PMID:14644432 RGD:2317401 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mfn2 mitofusin 2 treatment IEP RGD PMID:24721408 RGD:13204835 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir1 microRNA 1 treatment IMP RGD PMID:29741915 RGD:13800564 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir10a microRNA 10a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir10b microRNA 10b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546 		JBrowse link
G Mir126a microRNA 126a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir134 microRNA 134 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,748,908...128,748,980 JBrowse link
G Mir137 microRNA 137 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:206,480,881...206,480,982
Ensembl chr 2:206,480,884...206,480,985 		JBrowse link
G Mir140 microRNA 140 exacerbates ISO miRNA:increased expression:heart, endothelial cells (mouse) RGD PMID:30259997 PMID:31792649 RGD:329337366, RGD:329337374 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir142 microRNA 142 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir145 microRNA 145 treatment IEP RNA:decreased expression:heart RGD PMID:31583047 PMID:33658472 RGD:155230831, RGD:329955358 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir146b microRNA 146b IEP miRNA:increased expression:heart (rat) RGD PMID:19380620 RGD:155882541 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir181c microRNA 181c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Mir183 microRNA 183 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723 		JBrowse link
G Mir186 microRNA 186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891 		JBrowse link
G Mir188 microRNA 188 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:15,247,715...15,247,794
Ensembl chr  X:15,247,715...15,247,794 		JBrowse link
G Mir193a microRNA 193a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:64,672,343...64,672,454
Ensembl chr10:64,672,343...64,672,454 		JBrowse link
G Mir196b microRNA 196b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 4:81,330,487...81,330,571
Ensembl chr 4:81,330,487...81,330,571 		JBrowse link
G Mir206 microRNA 206 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332 		JBrowse link
G Mir20b microRNA 20b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282 		JBrowse link
G Mir21 microRNA 21 exacerbates ISO
IEP		 CTD Direct Evidence: marker/mechanism
miRNA:increased expression:heart (rat)		 CTD
RGD		 PMID:22050707 PMID:24825878 PMID:19380620 RGD:41404665, RGD:155882541 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir210 microRNA 210 sexual_dimorphism IEP
ISO		 miRNA:increased expression:myocardium (human) RGD PMID:28661226 PMID:35296158 RGD:155260328, RGD:155663666 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir222 microRNA 222 ameliorates ISO RGD PMID:25863248 RGD:152025190 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir23b microRNA 23b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763 		JBrowse link
G Mir26a microRNA 26a treatment IEP RGD PMID:29978610 RGD:13792725 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir27a microRNA 27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir28 microRNA 28 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608 		JBrowse link
G Mir296 microRNA 296 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915 		JBrowse link
G Mir301b microRNA 301b ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr11:83,879,816...83,879,893
Ensembl chr11:83,879,816...83,879,893 		JBrowse link
G Mir30a microRNA 30a treatment IEP RGD PMID:25137026 RGD:35673319 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mir30c1 microRNA 30c-1 ISO CTD Direct Evidence: therapeutic CTD PMID:34217758 NCBI chr 5:134,349,237...134,349,325
Ensembl chr 5:134,349,237...134,349,325 		JBrowse link
G Mir320a microRNA 320a treatment
ameliorates		 IMP
ISO		 RGD PMID:27175593 PMID:19380620 PMID:30840298 PMID:25268616 RGD:155882540, RGD:155882541, RGD:155882546, RGD:155882578 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473 		JBrowse link
G Mir330 microRNA 330 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274 		JBrowse link
G Mir331 microRNA 331 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485 		JBrowse link
G Mir337 microRNA 337 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,538,903...128,538,999
Ensembl chr 6:128,538,902...128,538,998 		JBrowse link
G Mir346 microRNA 346 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr16:10,218,118...10,218,215
Ensembl chr16:10,218,118...10,218,215 		JBrowse link
G Mir34c microRNA 34c ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mir361 microRNA 361 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275 		JBrowse link
G Mir375 microRNA 375 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir411 microRNA 411 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,723,189...128,723,264
Ensembl chr 6:128,723,184...128,723,279 		JBrowse link
G Mir429 microRNA 429 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543 		JBrowse link
G Mir433 microRNA 433 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217 		JBrowse link
G Mir451a microRNA 451a ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Mir494 microRNA 494 ameliorates ISO RGD PMID:33982231 PMID:20837890 PMID:20837890 RGD:155883171, RGD:155883174, RGD:155883174 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir500 microRNA 500 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:15,258,778...15,258,857
Ensembl chr  X:15,258,768...15,258,859 		JBrowse link
G Mir503 microRNA 503 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393 		JBrowse link
G Mir542 microRNA 542 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:132,802,623...132,802,701
Ensembl chr  X:132,802,623...132,802,701 		JBrowse link
G Mir582 microRNA 582 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651 		JBrowse link
G Mir598 microRNA 598 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr15:37,962,692...37,962,770
Ensembl chr15:37,962,692...37,962,771 		JBrowse link
G Mir743a microRNA 743a EXP CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr  X:145,402,692...145,402,767
Ensembl chr  X:145,402,692...145,402,767 		JBrowse link
G Mirlet7i microRNA let-7i ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571 		JBrowse link
G Mki67 marker of proliferation Ki-67 IDA RGD PMID:22405128 RGD:6483543 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp1 matrix metallopeptidase 1 ISO
IEP		 RGD PMID:12892382 PMID:17996137 RGD:1582539, RGD:7207397 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment ISO
IEP		 RGD PMID:16699069 PMID:23889688 RGD:1582614, RGD:8657084 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mstn myostatin ISO mRNA, protein:increased expression:heart (mouse) RGD PMID:30765322 RGD:329849112 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor IDA RGD PMID:14962484 RGD:1302746 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415 		JBrowse link
G Ncl nucleolin IEP protein:decreased expression:heart RGD PMID:23594402 RGD:9686384 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136 		JBrowse link
G Ndufs1 NADH:ubiquinone oxidoreductase core subunit S1 treatment IDA RGD PMID:21700931 RGD:13801200 NCBI chr 9:64,546,430...64,579,751
Ensembl chr 9:64,546,225...64,579,893 		JBrowse link
G Nfe2l1 NFE2 like bZIP transcription factor 1 treatment IEP RGD PMID:20501665 RGD:10003160 NCBI chr10:81,796,055...81,812,926
Ensembl chr10:81,800,366...81,832,318 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 ISO RGD PMID:24915518 RGD:10412738 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha treatment IDA RGD PMID:19304943 RGD:10413871 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 IEP
ISO		 mRNA:decreased expression:heart (rat)
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:12003803 PMID:12087064 PMID:14990356 PMID:19207477 PMID:20828608 More... RGD:5509098 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP
IMP
ISO
IDA		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:12354446 PMID:20828747 PMID:18390819 PMID:29299201 PMID:29274587 RGD:4891991, RGD:2292091, RGD:13503347, RGD:13504684 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nox1 NADPH oxidase 1 IEP mRNA:increased expression:heart RGD PMID:33658472 RGD:329955358 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nppb natriuretic peptide B IDA RGD PMID:21168723 RGD:5685663 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nppc natriuretic peptide C IDA RGD PMID:15337698 RGD:1580149 NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251 		JBrowse link
G Npr3 natriuretic peptide receptor 3 IDA RGD PMID:15337698 RGD:1580149 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955 		JBrowse link
G Npy1r neuropeptide Y receptor Y1 IEP mRNA:decreased expression:heart left ventricle RGD PMID:17562528 RGD:1642307 NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 treatment IMP RGD PMID:12384456 RGD:628368 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Oprd1 opioid receptor, delta 1 IDA RGD PMID:12136724 RGD:2316590 NCBI chr 5:144,306,188...144,340,960
Ensembl chr 5:144,306,188...144,340,960 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IMP RGD PMID:19234577 RGD:2304087 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G P2ry12 purinergic receptor P2Y12 ISO RGD PMID:20431845 RGD:6480645 NCBI chr 2:143,481,468...143,523,340
Ensembl chr 2:143,481,430...143,523,361 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 ISO RGD PMID:9670921 PMID:23598272 RGD:5683917, RGD:11073735 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pawr pro-apoptotic WT1 regulator treatment IMP RGD PMID:18055876 RGD:9835369 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 IEP RGD PMID:12872233 RGD:1624250 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 IMP RGD PMID:8989147 RGD:2311662 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Phlda3 pleckstrin homology-like domain, family A, member 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34351043 NCBI chr13:47,193,250...47,196,335
Ensembl chr13:47,193,086...47,196,335 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma ISO RGD PMID:20179753 RGD:6482687 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043 		JBrowse link
G Plcd1 phospholipase C, delta 1 IDA protein:altered activity RGD PMID:12623065 RGD:1304368 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186 		JBrowse link
G Pld2 phospholipase D2 IDA protein:altered activity:sarcolemma, sarcoplasmic reticulum, heart left ventricle RGD PMID:15752718 RGD:2299906 NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808 		JBrowse link
G Pln phospholamban treatment IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10734148 PMID:21934351 RGD:7327186 NCBI chr20:32,629,537...32,639,559 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha ISO CTD Direct Evidence: therapeutic CTD PMID:16411023 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta IDA RGD PMID:19997057 RGD:2324876 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO RGD PMID:18562925 RGD:2301853 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha treatment ISO RGD PMID:19096023 RGD:10059669 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 treatment IEP RGD PMID:20501665 RGD:10003160 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Prkcb protein kinase C, beta IDA RGD PMID:15878997 RGD:1625520 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkcd protein kinase C, delta IEP protein:decreased expression:heart RGD PMID:17322024 RGD:1642542 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkd1 protein kinase D1 ameliorates ISO RGD PMID:24345679 RGD:307727199 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 treatment IMP RGD PMID:18332860 PMID:19845676 RGD:7777120, RGD:7777130 NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080 		JBrowse link
G Procr protein C receptor treatment IDA RGD PMID:26994471 RGD:13515126 NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903 		JBrowse link
G Pten phosphatase and tensin homolog treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19038262 PMID:20951693 RGD:127285611 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptger3 prostaglandin E receptor 3 treatment IMP RGD PMID:10193764 RGD:10043342 NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:17660401 RGD:2300261 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family treatment IDA RGD PMID:20501665 RGD:10003160 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit treatment IDA
IEP		 protein:altered localization:nucleus RGD PMID:18636044 PMID:31583047 RGD:2298773, RGD:155230831 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rhoa ras homolog family member A IEP protein:altered localization:heart RGD PMID:17322412 RGD:1642967 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rnf41 ring finger protein 41 severity ISO RGD PMID:21312039 RGD:401827146 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511 		JBrowse link
G Rnls renalase, FAD-dependent amine oxidase ISO RGD PMID:21178975 PMID:21178975 RGD:7327174, RGD:7327174 NCBI chr 1:231,037,481...231,309,855
Ensembl chr 1:231,037,486...231,309,823 		JBrowse link
G S100b S100 calcium binding protein B IEP mRNA, protein:increased expression:myocardium RGD PMID:21663912 RGD:5508825 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Selp selectin P IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12087064 PMID:21146547 RGD:6480105 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N ISO RGD PMID:7562495 RGD:5147423 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:26958805 RGD:11073621 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:16942749 RGD:8661647 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Sfrp2 secreted frizzled-related protein 2 IEP RGD PMID:19109969 RGD:4107088 NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063 		JBrowse link
G Sh2b3 SH2B adaptor protein 3 IMP RGD PMID:25628389 RGD:12904914 NCBI chr12:34,731,934...34,753,617
Ensembl chr12:34,731,911...34,753,616 		JBrowse link
G Sh2b3em2Mcwi SH2B adaptor protein 3; zinc finger nuclease induced mutant 2, Medical College of Wisconsin IMP RGD PMID:25628389 RGD:12904914
G Shh sonic hedgehog signaling molecule IEP protein:increased expression:heart RGD PMID:18228117 RGD:2306299 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sirt1 sirtuin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:21060073 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 treatment IEP RGD PMID:24126566 RGD:9681554 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 IEP RGD PMID:10336852 RGD:12879857 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 IEP RGD PMID:10336852 RGD:12879857 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 IDA
IMP
ISO		 protein:increased activity:cardiac muscle cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15215644 PMID:17267548 PMID:17822695 RGD:1642729, RGD:1642716 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 IMP RGD PMID:22803959 RGD:6771238 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Smad1 SMAD family member 1 ISO RGD PMID:15911698 RGD:1643233 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad3 SMAD family member 3 treatment IDA RGD PMID:22913380 RGD:12903950 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad4 SMAD family member 4 treatment IEP RGD PMID:22913380 RGD:12903950 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO
IDA		 human protein in a rat model RGD PMID:19277497 PMID:23629152 PMID:12668130 RGD:8655884, RGD:8655965, RGD:11035287 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 treatment ISO RGD PMID:11864929 PMID:12668130 RGD:1581222, RGD:11035287 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sord sorbitol dehydrogenase IEP
ISO		 protein:increased activity:heart
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18549825 PMID:14525943 RGD:1601364 NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:15165989 RGD:1581342 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 IDA protein:increased phosphorylation:heart RGD PMID:16935931 RGD:1600091 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IDA RGD PMID:23796350 RGD:8694332 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Suv39h1 SUV39H1 histone lysine methyltransferase treatment IDA associated with Diabetes Mellitus, Experimental RGD PMID:24752040 RGD:9586740 NCBI chr  X:14,421,028...14,433,993
Ensembl chr  X:14,421,109...14,433,982 		JBrowse link
G Tek TEK receptor tyrosine kinase IEP mRNA, protein:increased expression:ventricle myocardium RGD PMID:12737621 RGD:1601505 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tfrc transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18549825 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 treatment IEP RGD PMID:22913380 RGD:12903950 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thbs1 thrombospondin 1 IEP mRNA:increased expression:heart RGD PMID:16179730 RGD:2317960 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Timp4 TIMP metallopeptidase inhibitor 4 IEP protein:increased expression:blood RGD PMID:12707244 RGD:2290461 NCBI chr 4:148,306,021...148,312,558
Ensembl chr 4:148,304,490...148,312,558 		JBrowse link
G Tlr2 toll-like receptor 2 IEP RGD PMID:19274437 RGD:2312688 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 IDA RGD PMID:14962484 RGD:1302746 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnc tenascin C IEP RGD PMID:20554738 RGD:4889599 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor treatment IEP protein:increased expression:serum, heart: RGD PMID:24157164 PMID:31583047 RGD:7387274, RGD:155230831 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnni3 troponin I3, cardiac type ameliorates ISO RGD PMID:30259997 RGD:329337366 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
G Tp53 tumor protein p53 IEP protein:increased expression:heart RGD PMID:18317410 RGD:2290554 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Txn1 thioredoxin 1 IEP mRNA:decreased expression:heart RGD PMID:18045550 RGD:2306159 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txn2 thioredoxin 2 IEP mRNA, protein:decreased expression:heart RGD PMID:18045550 RGD:2306159 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359 		JBrowse link
G Ucn urocortin IDA RGD PMID:15806110 RGD:1642783 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
G Ucp2 uncoupling protein 2 IEP mRNA:increased expression:myocardium RGD PMID:19526854 RGD:2313528 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Ucp3 uncoupling protein 3 IEP mRNA:increased expression:myocardium RGD PMID:19526854 RGD:2313528 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762 		JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:17900760 RGD:2306836 NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237 		JBrowse link
G Uts2r urotensin 2 receptor IMP RGD PMID:17900760 RGD:2306836 NCBI chr10:106,438,092...106,439,252
Ensembl chr10:106,438,092...106,439,252 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 IEP protein:increased expression:heart RGD PMID:23052973 RGD:7207792 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vcan versican IEP mRNA:increased expression:heart RGD PMID:16311904 RGD:1598497 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25488258 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vdr vitamin D receptor ISO mRNA,protein:increased expression, activity:heart: RGD PMID:25365634 RGD:13432076 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:22050707 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xdh xanthine dehydrogenase IEP RGD PMID:3162724 RGD:13209131 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xiap X-linked inhibitor of apoptosis treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14998631 PMID:20501665 RGD:10003160 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase ISO mRNA,protein:increased expression:myocardium (mouse) RGD PMID:30259997 RGD:329337366 NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837 		JBrowse link
Ovary Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F3 coagulation factor III, tissue factor treatment IEP RGD PMID:26370456 RGD:11341710 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
Primary Graft Dysfunction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 exacerbates IEP protein:increased expression:urine (rat) RGD PMID:19921985 RGD:150517553 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:12244161 RGD:7248713 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Gata2 GATA binding protein 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO RGD PMID:29290803 RGD:401827126 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IMP RGD PMID:22617707 PMID:10666412 RGD:8547722, RGD:11520779 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:21911153 RGD:11049478 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Npy neuropeptide Y IEP mRNA, protein:decreased expression:blood, mononuclear cell RGD PMID:18981110 RGD:10448956 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Pf4 platelet factor 4 ameliorates IDA RGD PMID:24986443 RGD:329901907 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Selp selectin P ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845 		JBrowse link
G Senp1 SUMO specific peptidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598 		JBrowse link
G Tnf tumor necrosis factor treatment IEP liver RGD PMID:18972563 RGD:15023490 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:28569748 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
Retina Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 treatment IDA RGD PMID:22143029 RGD:5686888 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Bad BCL2-associated agonist of cell death treatment IDA RGD PMID:23056591 RGD:10053711 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:23056591 RGD:10053711 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IDA RGD PMID:25535961 RGD:11522737 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 treatment IEP RGD PMID:23056591 RGD:10053711 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:10549664 RGD:8655861 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Casp7 caspase 7 IEP RGD PMID:20702827 RGD:5684535 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Cat catalase treatment IEP protein:decreased expression,decreased activity:retina: RGD PMID:22509733 RGD:9068919 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IDA RGD PMID:24325836 RGD:11526144 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Clu clusterin IEP RGD PMID:15139011 RGD:1581194 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cntf ciliary neurotrophic factor treatment IDA RGD PMID:8125754 RGD:8655591 NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Dusp1 dual specificity phosphatase 1 treatment IMP RGD PMID:21094639 RGD:7495849 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Fgf2 fibroblast growth factor 2 treatment IEP
ISO		 RGD PMID:9561364 PMID:8125754 PMID:14975212 RGD:8554857, RGD:8655591, RGD:8655585 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fxn frataxin ameliorates ISO RGD PMID:27537261 PMID:27537261 RGD:401793704, RGD:401793704 NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540 		JBrowse link
G Glul glutamate-ammonia ligase treatment IEP RGD PMID:22008240 RGD:401794422 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Hdac2 histone deacetylase 2 treatment ISO RGD PMID:23696608 RGD:9590210 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hgf hepatocyte growth factor treatment ISO
IEP		 mRNA,protein:increased expression:retina: RGD PMID:11818401 PMID:11818401 RGD:8548551, RGD:8548551 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hmgb1 high mobility group box 1 IDA RGD PMID:21999229 RGD:10402064 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 IEP associated with Glaucoma RGD PMID:20357190 RGD:4145289 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IDA RGD PMID:21310899 RGD:10402767 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IMP
IEP		 associated with Hypertension RGD PMID:10235552 PMID:15007035 RGD:8547704, RGD:8547707 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il1a interleukin 1 alpha IEP RGD PMID:7890488 RGD:7401191 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta IEP RGD PMID:7890488 RGD:7401191 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 IEP mRNA:increased expression:retina: RGD PMID:16530172 RGD:7829807 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP
ISO		 mRNA:decreased expression:retina
protein:decreased expression:retina, blood vessel		 RGD PMID:16330144 PMID:20132867 RGD:8662868, RGD:8662890 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 IEP protein:increased expression:retina RGD PMID:17026968 RGD:2317696 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IEP RGD PMID:19668425 RGD:7495824 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP
IDA		 mRNA:altered expression:retina (rat)
protein:increased expression:retinal vasculature, retinal ganglion cell layer (rat)		 RGD PMID:9950605 PMID:11496119 PMID:12634478 RGD:7771570, RGD:7775036, RGD:7775037 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase IEP protein:increased expression:retina, cytosol (rat) RGD PMID:19122832 RGD:13208943 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Ren renin treatment IMP RGD PMID:24709336 RGD:11039406 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G Rnf2 ring finger protein 2 IEP RGD PMID:20740046 RGD:9491844 NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099 		JBrowse link
G Serpinf1 serpin family F member 1 ISO human protein in a mouse model RGD PMID:16822505 RGD:8554871 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sod2 superoxide dismutase 2 treatment IEP
ISO		 protein:decreased activity:retina: RGD PMID:22240151 PMID:22240151 RGD:8158043, RGD:8158043 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 treatment IDA RGD PMID:21858029 RGD:8694310 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tlr4 toll-like receptor 4 ISO RGD PMID:21031135 RGD:7794771 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tnf tumor necrosis factor IEP
IMP
IDA		 protein:increased expression:retina: RGD PMID:18660426 PMID:18660426 PMID:18660426 RGD:7387281, RGD:7387281, RGD:7387281 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A IDA RGD PMID:17591953 RGD:7421609 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xdh xanthine dehydrogenase treatment IMP RGD PMID:9288448 RGD:13210506 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
Skeletal Muscle Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed IMP RGD PMID:7858993 RGD:10450555 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Itgam integrin subunit alpha M treatment IEP RGD PMID:26315464 PMID:19105227 RGD:329901918, RGD:329902055 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO RGD PMID:29395422 PMID:24585935 RGD:13525001, RGD:13542089 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
Spinal Cord Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bad BCL2-associated agonist of cell death treatment IDA RGD PMID:23643992 RGD:10053660 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bdnf brain-derived neurotrophic factor treatment IEP RGD PMID:24361987 RGD:10059358 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:25374587 RGD:11561952 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 treatment IDA RGD PMID:25301568 RGD:13782374 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 treatment IEP RGD PMID:25301568 RGD:13782374 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 treatment IEP RGD PMID:17368520 PMID:29310813 RGD:155226865, RGD:155226868 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IMP RGD PMID:27760212 RGD:12910551 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 IMP RGD PMID:27760212 RGD:12910551 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase treatment IEP RGD PMID:30195603 RGD:13792615 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP protein:increased expression:spinal cord: RGD PMID:24463125 RGD:11354961 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa treatment ISO RGD PMID:10903607 RGD:11100044 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 treatment IEP RGD PMID:30195603 RGD:13792615 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Tlr4 toll-like receptor 4 IMP RGD PMID:27760212 RGD:12910551 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
Testis Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 treatment IEP RGD PMID:27748062 RGD:13703108 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator IEP RGD PMID:26754107 RGD:11555349 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator IEP RGD PMID:26754107 RGD:11555349 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 IEP RGD PMID:26754107 RGD:11555349 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 IEP RGD PMID:26754107 RGD:11555349 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:testes (rat) RGD PMID:12193413 RGD:632997 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 treatment IMP RGD PMID:23142244 RGD:10755740 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 treatment IMP RGD PMID:15944243 RGD:13800876 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 treatment IMP RGD PMID:15944243 RGD:13800876 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nos3 nitric oxide synthase 3 IEP protein:increased expression:testis RGD PMID:18205898 RGD:2292105 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 IEP mRNA, protein:decreased expression:testis RGD PMID:24189580 RGD:9588240 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Xdh xanthine dehydrogenase treatment IDA RGD PMID:23769121 RGD:7247698 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
transient cerebral ischemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvrl1 activin A receptor like type 1 IEP RGD PMID:15781474 RGD:1579751 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 IEP mRNA, protein:increased expression:brain RGD PMID:16630594 RGD:9681747 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 IEP RGD PMID:16630594 RGD:9681747 NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 IMP RGD PMID:16504947 RGD:10755337 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: therapeutic CTD PMID:23437309 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP
ISO		 protein:altered expression:cerebral cortex, striatum (rat)
protein:increased expression:brain, plasma		 RGD PMID:22528836 PMID:23288172 RGD:7245542, RGD:8696004 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agt angiotensinogen IEP RGD PMID:21934531 RGD:8549480 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Ahr aryl hydrocarbon receptor treatment IMP RGD PMID:32913241 RGD:401793747 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 IEP
ISO		 mRNA:decreased expression, altered localization:CA1 pyramidal layer, nucleus:
protein:increased expression:nucleus:		 RGD PMID:14526224 PMID:15087715 RGD:10047409, RGD:10053562 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Ang angiogenin treatment IEP RGD PMID:30258350 RGD:155663419 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Ank1 ankyrin 1 IEP RGD PMID:9202331 RGD:1599109 NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759 		JBrowse link
G Ank2 ankyrin 2 IEP RGD PMID:9202331 RGD:1599109 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923 		JBrowse link
G Apoe apolipoprotein E IEP RGD PMID:19623195 RGD:6903926 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Aqp4 aquaporin 4 treatment IEP RGD PMID:24773551 RGD:13207320 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Atf2 activating transcription factor 2 IDA
IEP		 RGD PMID:10077326 PMID:9813301 RGD:10047405, RGD:10047413 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta IEP protein:increased expression:cerebrum (rat) RGD PMID:21950801 RGD:13792582 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Axin2 axin 2 treatment IEP RGD PMID:31650542 RGD:151356749 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bace1 beta-secretase 1 IEP protein:increased activity,increased expression:brain cortex RGD PMID:15120577 RGD:13782170 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Bad BCL2-associated agonist of cell death ISO CTD Direct Evidence: marker/mechanism CTD PMID:12629175 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator treatment IEP RGD PMID:21167243 RGD:10054102 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 IEP protein:increased expression:hippocampus CA1, pyramidal cell RGD PMID:12913114 RGD:634629 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator treatment IEP
IDA		 protein:decreased expression:brain RGD PMID:18083315 PMID:22509406 PMID:16732092 RGD:2290557, RGD:11561910, RGD:11522725 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l2 Bcl2-like 2 treatment IEP
ISO		 protein:increased expression:cortex and caudate putamen RGD PMID:10724126 PMID:12571640 RGD:14394498, RGD:14394500 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Becn1 beclin 1 treatment IEP RGD PMID:22509406 RGD:11561910 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bex3 brain expressed X-linked 3 IEP RGD PMID:11124986 RGD:9743974 NCBI chr  X:99,273,270...99,274,799
Ensembl chr  X:99,273,161...99,274,800 		JBrowse link
G Bnip3 BCL2 interacting protein 3 IEP RGD PMID:14972662 RGD:2314028 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G C3 complement C3 treatment IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23199288 PMID:22004711 RGD:7411628 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Cab39 calcium binding protein 39 IEP protein:increased expression:brain RGD PMID:27798271 RGD:14398833 NCBI chr 9:86,463,095...86,524,545
Ensembl chr 9:86,463,095...86,524,544 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha IEP
ISO		 protein:increased expression:hippocampus RGD PMID:12951199 PMID:12199152 RGD:7241547, RGD:13681927 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Casp3 caspase 3 IDA RGD PMID:21712070 RGD:10053706 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 treatment IEP RGD PMID:25872160 RGD:13782285 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 treatment IEP protein:increased expression:cerebral cortex: RGD PMID:30148677 PMID:18096138 RGD:13782286, RGD:4142863 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 IEP
ISO		 associated with Diabetes Mellitus, Experimental;protein:increased expression:neocortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11333366 PMID:15246841 PMID:21712070 RGD:2311321, RGD:10053706 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cav1 caveolin 1 treatment IEP
ISO		 RGD PMID:22007835 PMID:22007835 RGD:8661794, RGD:8661794 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cbl Cbl proto-oncogene treatment IDA RGD PMID:18773943 RGD:4108486 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cbs cystathionine beta synthase treatment ISO XCO:0000348
XCO:0000807		 RGD PMID:22212488 PMID:22212488 RGD:41410880, RGD:41410880 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 treatment IDA
IEP		 mRNA:increased expression:brain (rat) RGD PMID:21487414 PMID:7860708 RGD:8549519, RGD:8549729 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 treatment IMP RGD PMID:19428685 RGD:7488896 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccnh cyclin H IEP mRNA, protein:increased expression:hippocampus RGD PMID:10501206 RGD:69371 NCBI chr 2:15,835,064...15,855,648
Ensembl chr 2:15,834,833...15,855,819 		JBrowse link
G Ccr6 C-C motif chemokine receptor 6 IEP mRNA:increased expression:brain RGD PMID:19428685 RGD:7488896 NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603 		JBrowse link
G Cd40 CD40 molecule severity ISO RGD PMID:15795333 RGD:11352234 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand severity ISO RGD PMID:15795333 RGD:11352234 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 treatment IEP RGD PMID:28254431 RGD:13506925 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO protein:decreased expression:striatum, neuron RGD PMID:11438580 RGD:8552691 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha IEP mRNA, protein:increased expression:hippocampal pyramidal cell layer (rat) RGD PMID:9795105 RGD:10401192 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Chka choline kinase alpha IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:16300643 RGD:10401831 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516 		JBrowse link
G Coq7 coenzyme Q7, hydroxylase severity ISO RGD PMID:20170652 RGD:10402096 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 IDA RGD PMID:10077326 RGD:10047405 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator IEP mRNA:increased expression:cerebral cortex (rat) RGD PMID:12437578 RGD:632385 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:12624302 RGD:10450512 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 IEP protein:decreased expression:hippocampus RGD PMID:24447880 RGD:9491776 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 IEP mRNA,protein:decreased expression:hippocampus RGD PMID:24447880 RGD:9491776 NCBI chr 8:119,785,726...119,799,431
Ensembl chr 8:119,782,595...119,800,014 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 IEP protein:increased expression:hippocampus: RGD PMID:24924806 RGD:11352662 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cycs cytochrome c, somatic ISO CTD Direct Evidence: marker/mechanism CTD PMID:11333366 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Daxx death-domain associated protein treatment IDA
IEP		 mRNA,protein:increased expression:cerebral cortex: RGD PMID:17967739 PMID:18096138 RGD:9587802, RGD:4142863 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Dbn1 drebrin 1 IEP RGD PMID:8583659 RGD:10398814 NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Dffb DNA fragmentation factor subunit beta IEP mRNA, protein:increased expression:hippocampus CA1 RGD PMID:11425895 RGD:628524 NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 ameliorates
treatment
disease_progression		 ISO
IEP		 RGD PMID:31927543 PMID:30258350 PMID:30653356 RGD:155663354, RGD:155663419, RGD:155663383 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Dusp1 dual specificity phosphatase 1 IEP protein:increased expression:brain RGD PMID:22197701 RGD:7771582 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp16 dual specificity phosphatase 16 IEP protein:increased expression, altered localization:hippocampus, cytosol, nucleus RGD PMID:23280045 RGD:7775014 NCBI chr 4:167,546,780...167,630,173
Ensembl chr 4:167,548,155...167,629,980 		JBrowse link
G Eed embryonic ectoderm development IDA RGD PMID:24007266 RGD:9588303 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha ISO
IEP		 associated with Heart Arrest RGD PMID:11520898 PMID:10541873 RGD:10395353, RGD:11041881 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:19168036 RGD:10450558 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Elk1 ETS transcription factor ELK1 treatment IEP RGD PMID:17091294 RGD:7488902 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IEP mRNA:increased expression:brain: RGD PMID:9634555 RGD:9685492 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317 		JBrowse link
G Ep300 E1A binding protein p300 IEP mRNA:increased expression:cerebrum, ipsilateral side (rat) RGD PMID:22196858 RGD:7349341 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Epo erythropoietin treatment IEP
ISO		 RGD PMID:22282883 PMID:24702327 RGD:10401060, RGD:11041699 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit treatment ISO human gene in a rat model RGD PMID:19440222 RGD:2313668 NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor IEP mRNA, protein:increased expression:cerebral cortex RGD PMID:10437118 RGD:10401104 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587 		JBrowse link
G Esr1 estrogen receptor 1 treatment IDA RGD PMID:24548484 PMID:25098259 RGD:10045843, RGD:10045845 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 IMP RGD PMID:23593292 RGD:7364962 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F11r F11 receptor treatment IEP RGD PMID:22868201 RGD:7488943 NCBI chr13:83,873,797...83,897,388
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G F12 coagulation factor XII treatment ISO RGD PMID:16533887 PMID:16533887 RGD:11041786, RGD:11041786 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Fadd Fas associated via death domain IEP mRNA,protein:increased expression:cerebral cortex: RGD PMID:18096138 RGD:4142863 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653 		JBrowse link
G Fas Fas cell surface death receptor treatment IEP
IDA
ISO		 protein:increased expression:brain
protein:increased expression:brain (rat)		 RGD PMID:18410517 PMID:30301943 PMID:18981705 PMID:10972965 RGD:2311437, RGD:153297779, RGD:8686422, RGD:8662928 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 IEP mRNA:increased expression:cerebral cortex: RGD PMID:8858623 RGD:10402044 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 treatment IEP associated with Experimental Diabetes Mellitus RGD PMID:22432030 RGD:155882598 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 treatment ISO RGD PMID:17077813 RGD:10402150 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 IEP mRNA, protein:increased expression:striatum (rat) RGD PMID:22817682 RGD:11566024 NCBI chr  X:147,240,239...147,278,057
Ensembl chr  X:147,240,301...147,278,050 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase IEP
ISO		 protein:decreased expression:cerebral cortex
mRNA:decreased expression:cerebral cortex
mRNA:decreased expression:heart		 RGD PMID:32426101 PMID:36479246 PMID:34413770 RGD:329901764, RGD:329951019, RGD:329901768 NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:22580330 RGD:10449127 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gad1 glutamate decarboxylase 1 disease_progression IEP RGD PMID:20659561 RGD:401900597 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 disease_progression IEP RGD PMID:20659561 RGD:401900597 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gamt guanidinoacetate N-methyltransferase ameliorates ISO DNA:deletion RGD PMID:24004504 RGD:329955375 NCBI chr 7:9,448,590...9,451,413
Ensembl chr 7:9,448,628...9,451,778 		JBrowse link
G Gatm glycine amidinotransferase exacerbates ISO DNA:deletion RGD PMID:24004504 RGD:329955375 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Gch1 GTP cyclohydrolase 1 treatment IMP RGD PMID:9920651 RGD:329961573 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Ghsr growth hormone secretagogue receptor IEP mRNA,protein:decreased expression:brain: RGD PMID:17560544 RGD:12907500 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gja1 gap junction protein, alpha 1 treatment ISO
IEP		 protein:increased expression:brain RGD PMID:22812228 PMID:23328809 RGD:7207263, RGD:8662426 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Gjb6 gap junction protein, beta 6 IEP protein:increased expression:hippocampus: RGD PMID:21718970 RGD:6480433 NCBI chr15:31,284,561...31,294,552
Ensembl chr15:31,284,419...31,294,582 		JBrowse link
G Glrx glutaredoxin IEP mRNA,protein:decreased expression:brain: RGD PMID:10329397 RGD:9686043 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680 		JBrowse link
G Glul glutamate-ammonia ligase treatment IEP associated with carotid artery occlusion
protein:increased expression:hippocampus		 RGD PMID:27664163 PMID:25365917 PMID:21272618 PMID:21371894 RGD:401794415, RGD:401794591, RGD:401794590, RGD:401794419 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 treatment ISO
IDA		 human protein in a rat model RGD PMID:24407245 PMID:21361730 PMID:20145654 RGD:13504852, RGD:13504855, RGD:13504854 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gp6 glycoprotein VI ameliorates ISO RGD PMID:34237320 RGD:401794450 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Gpx3 glutathione peroxidase 3 treatment ISO RGD PMID:30098076 RGD:401827833 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A ameliorates
treatment		 IMP
IDA
ISO		 associated with hyperhomocysteinemia RGD PMID:30885791 PMID:12932824 PMID:30885791 RGD:401940141, RGD:401950480, RGD:401940141 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B ameliorates IMP RGD PMID:30885791 RGD:401940141 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Gsr glutathione-disulfide reductase treatment IDA RGD PMID:15525350 RGD:10401855 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H2ax H2A.X variant histone treatment IDA RGD PMID:20830300 RGD:8693742 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 treatment IEP RGD PMID:24771108 RGD:9686115 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha treatment IEP protein:increased expression:cerebral cortex, caudoputamen (rat) RGD PMID:20417628 PMID:30258350 RGD:9068877, RGD:155663419 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgb1 high mobility group box 1 ISO protein:increased expression:brain, plasma RGD PMID:23288172 RGD:8696004 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 IEP protein:altered expression:cerebral cortex, hippocampus (rat) RGD PMID:20421594 RGD:10041006 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B treatment IDA RGD PMID:22366221 RGD:9999181 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344 		JBrowse link
G Hrh2 histamine receptor H 2 IEP protein:decreased expression:caudate putamen (rat) RGD PMID:16181737 RGD:9685533 NCBI chr17:10,366,004...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Hsf1 heat shock transcription factor 1 treatment IEP
IDA		 protein:increased expression:brain, nucleus (rat)
associated with Heart Arrest		 RGD PMID:26070787 PMID:23528677 RGD:10402389, RGD:10402772 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 treatment IEP RGD PMID:25632565 RGD:11354959 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 IEP protein:increased expression:brain, postsynaptic density (rat) RGD PMID:9425004 RGD:10059344 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP protein:increased expression:brain,astrocyte: RGD PMID:10559386 RGD:10402577 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Htra2 HtrA serine peptidase 2 treatment IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15306124 PMID:19462455 RGD:10402932 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Htt huntingtin IEP protein:increased degradation:brain RGD PMID:12957494 RGD:1304431 NCBI chr14:75,845,836...75,996,094
Ensembl chr14:75,845,836...75,995,070 		JBrowse link
G Icam1 intercellular adhesion molecule 1 treatment IEP RGD PMID:22379785 RGD:8547729 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifnb1 interferon beta 1 ameliorates IDA RGD PMID:12973019 RGD:401851924 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Igf1 insulin-like growth factor 1 severity IEP protein:decreased expression:serum (rat) RGD PMID:25098324 RGD:12904924 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta treatment IEP RGD PMID:24261295 RGD:7495766 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250 		JBrowse link
G Il10 interleukin 10 treatment IDA RGD PMID:24053818 RGD:7364868 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta IDA
ISO		 RGD PMID:23147509 PMID:22284622 RGD:7175551, RGD:7175554 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IDA
ISO		 human protein in a rat model RGD PMID:15837124 PMID:20412072 RGD:1626674, RGD:8551852 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Ilk integrin-linked kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:15472100 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Itgam integrin subunit alpha M treatment ISO
IEP
IMP		 mRNA:increased expression:cerebral cortex (mouse)
mRNA:increased expression:brain (rat)		 RGD PMID:30123113 PMID:23844255 PMID:22082476 PMID:32407868 PMID:19563786 More... RGD:329853754, RGD:329902067, RGD:329902058, RGD:329901940, RGD:329901933, RGD:329901921, RGD:329901917, RGD:329901916 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb3 integrin subunit beta 3 IEP RGD PMID:18638458 RGD:6907424 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 IEP mRNA:decreased expression:cerebral cortex (rat) RGD PMID:7500836 RGD:6482813 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Jak1 Janus kinase 1 IEP RGD PMID:10756075 RGD:19165138 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 IDA RGD PMID:23764464 RGD:8694326 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 IEP protein:decreased expression:CA1 field of hippocampus, astrocyte, astrocyte projection RGD PMID:20833221 RGD:8662899 NCBI chr13:84,802,026...84,835,383
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 severity
treatment		 ISO
IDA
IEP		 protein:increased expression:cerebral cortex (rat) RGD PMID:15175651 PMID:24154701 PMID:25062759 RGD:9831121, RGD:9831178, RGD:9831122 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Kdm1a lysine demethylase 1A IEP protein:increased expression:cerebral cortex, hippocampus, dentate gyrus (rat) RGD PMID:20542065 RGD:9588301 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 ISO protein:decreased expression:brain (mouse) RGD PMID:21075092 RGD:6893270 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Klf5 KLF transcription factor 5 ameliorates IMP RGD PMID:32272873 RGD:45073134 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Kmt2a lysine methyltransferase 2A treatment IMP RGD PMID:34694864 RGD:155888565 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Lcn2 lipocalin 2 IEP protein:increased expression:brain RGD PMID:29122651 PMID:24916903 RGD:126781757, RGD:126790489 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lmna lamin A/C IDA RGD PMID:17683050 RGD:2293745 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 treatment IDA RGD PMID:17173873 RGD:9850154 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Ltbp1 latent transforming growth factor beta binding protein 1 treatment IEP RGD PMID:11720783 RGD:10412057 NCBI chr 6:20,029,629...20,425,339
Ensembl chr 6:20,029,629...20,425,349 		JBrowse link
G Madd MAP-kinase activating death domain IEP RGD PMID:12625816 RGD:9588641 NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha treatment IEP RGD PMID:22509406 RGD:11561910 NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 IDA protein:increased threonine phosphorylation:heart, nucleus RGD PMID:9195981 RGD:7495830 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IEP protein:increased nitrosylation, activity:hippocampus: RGD PMID:23137546 RGD:10412334 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 ameliorates ISO RGD PMID:32078472 PMID:32349637 PMID:34628598 PMID:32382778 RGD:155791642, RGD:155804284, RGD:155804283, RGD:155804272 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 treatment IDA RGD PMID:18498770 PMID:18382279 RGD:7495845, RGD:7495847 NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493 		JBrowse link
G Mbd1 methyl-CpG binding domain protein 1 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr18:67,869,870...67,884,501
Ensembl chr18:67,869,992...67,886,554 		JBrowse link
G Mbd2 methyl-CpG binding domain protein 2 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr18:64,174,002...64,240,795
Ensembl chr18:64,174,002...64,240,794 		JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 IEP mRNA:decreased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165 		JBrowse link
G Mbp myelin basic protein IEP mRNA:increased expression:oligodendrocyte: RGD PMID:11460777 RGD:7349336 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcfd2 multiple coagulation factor deficiency 2, ER cargo receptor complex subunit IEP mRNA:increased expression:hippocampus RGD PMID:17610559 RGD:11062141 NCBI chr 6:7,274,469...7,285,841
Ensembl chr 6:7,274,469...7,285,841 		JBrowse link
G Mdm2 MDM2 proto-oncogene treatment IDA RGD PMID:24334056 RGD:10412310 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IEP mRNA:increased expression:hippocampus RGD PMID:12421618 RGD:9587846 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mff mitochondrial fission factor treatment IDA RGD PMID:26116440 RGD:12879457 NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039 		JBrowse link
G Mfn2 mitofusin 2 IEP protein:decreased expression:brain (rat) RGD PMID:25147362 RGD:13204807 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mir126a microRNA 126a exacerbates ISO RGD PMID:28101763 RGD:401850574 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir155 microRNA 155 treatment IEP RGD PMID:33081480 RGD:151347423 NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718 		JBrowse link
G Mir195 microRNA 195 severity IMP RGD PMID:32272873 RGD:45073134 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mir223 microRNA 223 IMP RGD PMID:31237865 RGD:25824937 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mmp2 matrix metallopeptidase 2 treatment IDA
IEP		 protein:increased activity, increased expression:brain RGD PMID:11592852 PMID:24828425 RGD:8547930, RGD:8657086 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 treatment ISO
IEP
IDA		 protein:increased activity, increased expression:brain RGD PMID:16197500 PMID:24773551 PMID:23046750 PMID:11592852 RGD:8547921, RGD:13207320, RGD:13207323, RGD:8547930 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mt1 metallothionein 1 IEP mRNA:increased expression:cerebral cortex RGD PMID:10884303 RGD:10412650 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A IEP mRNA:increased expression:cerebral cortex RGD PMID:10884303 RGD:10412650 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 IEP mRNA, protein:increased expression:brain RGD PMID:10069533 RGD:9685804 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IEP RGD PMID:30712471 RGD:155791663 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myb MYB proto-oncogene, transcription factor IEP mRNA:increased expression:brain: RGD PMID:24828495 RGD:11532683 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase treatment IMP
ISO		 RGD PMID:28528966 PMID:25603815 RGD:13781879, RGD:13781895 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Ndrg2 NDRG family member 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23451161 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626 		JBrowse link
G Ndrg4 NDRG family member 4 ISO RGD PMID:21636852 RGD:7247728 NCBI chr19:9,351,408...9,387,398
Ensembl chr19:9,351,404...9,386,914 		JBrowse link
G Nefh neurofilament heavy chain IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nefl neurofilament light chain IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nefm neurofilament medium chain IEP protein:decreased expression:hippocampus RGD PMID:8726968 RGD:9743938 NCBI chr15:42,360,449...42,365,753
Ensembl chr15:42,360,454...42,365,755 		JBrowse link
G Nf1 neurofibromin 1 IEP mRNA,protein:increased expression:astrocyte: RGD PMID:8820972 RGD:12789703 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IEP protein:increased expression:hippocampal pyramidal neuron, nucleus (rat) RGD PMID:9158652 RGD:10045943 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Ngb neuroglobin treatment IEP
ISO
IMP		 associated with Hypertension;mRNA, protein:decreased expression:brain RGD PMID:16647691 PMID:23342777 PMID:12621155 PMID:12621155 RGD:9743952, RGD:9743965, RGD:9743964, RGD:9743964 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830 		JBrowse link
G Ngfr nerve growth factor receptor IEP RGD PMID:11124986 RGD:9743974 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 ISO mRNA, protein:increased expression:brain RGD PMID:20863826 RGD:5508733 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Nono non-POU domain containing, octamer-binding ISO protein:altered localization:cerebral cortex (mouse) RGD PMID:29426953 RGD:155883175 NCBI chr  X:66,554,131...66,571,992
Ensembl chr  X:66,554,098...66,571,952 		JBrowse link
G Nos1 nitric oxide synthase 1 IDA protein:increased serine phosphorylation:dentate gyrus RGD PMID:23806217 RGD:7257600 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IEP
IDA		 protein:increased expression:serum (rat) RGD PMID:28944915 PMID:29298658 PMID:29312485 RGD:13450951, RGD:13503353, RGD:13503330 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 treatment IEP RGD PMID:30258350 RGD:155663419 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Nox1 NADPH oxidase 1 ameliorates IMP RGD PMID:25617620 RGD:329955357 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP protein:increased expression:cerebral cortex (rat)
protein:increased expression:brain (rat)		 RGD PMID:29017857 PMID:28169530 PMID:28552673 RGD:13439718, RGD:13442499, RGD:13439727 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrg1 neuregulin 1 treatment ISO RGD PMID:31560696 RGD:405649728 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrp1 neuropilin 1 IEP mRNA:increased expression:brain RGD PMID:33675584 RGD:401901171 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrxn1 neurexin 1 IEP associated with Hypertension;mRNA:decreased expression:cerebral cortex RGD PMID:12437578 RGD:632385 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase IEP protein:increased expression:cerebral cortex RGD PMID:14600440 RGD:8657406 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase treatment ISO
IDA		 protein:altered expression:brain RGD PMID:22345048 PMID:24633199 RGD:7800722, RGD:13208946 NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109 		JBrowse link
G Optn optineurin IEP protein:decreased expression:cerebral cortex (rat) RGD PMID:24235151 RGD:13434905 NCBI chr17:73,209,572...73,260,251
Ensembl chr17:73,209,575...73,260,251 		JBrowse link
G Parl presenilin associated, rhomboid-like severity ISO RGD PMID:23921894 RGD:12902620 NCBI chr11:80,594,059...80,620,506
Ensembl chr11:80,593,192...80,620,506 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 treatment IDA
IEP		 RGD PMID:19840223 PMID:19840223 RGD:2325713, RGD:2325713 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pawr pro-apoptotic WT1 regulator IEP
ISO		 mRNA:increased expression:brain:
protein:increased expression:cortex,striatum:		 RGD PMID:14705148 PMID:11323519 RGD:1302269, RGD:9835381 NCBI chr 7:43,645,028...43,725,033
Ensembl chr 7:43,645,084...43,725,028 		JBrowse link
G Pax6 paired box 6 IEP protein:increased expression:cerebral cortex, striatum, astroglial cell (rat) RGD PMID:24114637 RGD:8552354 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pcna proliferating cell nuclear antigen IEP RGD PMID:9757027 RGD:10448974 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pde4d phosphodiesterase 4D IEP protein:increased expression:hippocampus CA1 RGD PMID:22860212 RGD:7327148 NCBI chr 2:40,014,933...41,529,190
Ensembl chr 2:40,019,933...41,525,884 		JBrowse link
G Pdyn prodynorphin IEP mRNA:decreased expression:dentate gyrus, granule cell RGD PMID:8914861 RGD:401851049 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 ISO protein:increased expression:brain (mouse) RGD PMID:22382321 RGD:6766379 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Plat plasminogen activator, tissue type IEP Protein:increased expression, increased activity:hippocampus (rat) RGD PMID:15882815 RGD:1580875 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase IEP
IDA		 protein:increased expression:cerebral cortex (rat) RGD PMID:21375013 PMID:19952306 RGD:7241584, RGD:7241795 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plxnd1 plexin D1 ameliorates IMP RGD PMID:30653356 RGD:155663383 NCBI chr 4:149,002,786...149,043,097
Ensembl chr 4:149,002,784...149,043,244 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IMP
IEP		 RGD PMID:18378216 PMID:19221220 PMID:18973594 RGD:2301892, RGD:8553032, RGD:2301866 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A IEP protein:increased expression:cerebral cortex (rat) RGD PMID:15255948 RGD:9999154 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A treatment IDA RGD PMID:21278085 RGD:10043805 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Ppp2r5e protein phosphatase 2 regulatory subunit B', epsilon treatment IEP RGD PMID:30712471 RGD:155791663 NCBI chr 6:94,168,846...94,317,872
Ensembl chr 6:94,168,846...94,317,872 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase ISO protein:decreased expression:cerebral cortex, striatum: RGD PMID:12415119 RGD:10413862 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptafr platelet-activating factor receptor treatment IEP
IMP		 mRNA:decreased expression:cerebral cortex (rat) RGD PMID:17268849 PMID:8158141 RGD:9999221, RGD:10043297 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Pten phosphatase and tensin homolog IEP RGD PMID:12414116 RGD:1358425 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptger4 prostaglandin E receptor 4 IEP protein:increased expression:hippocampus (rat) RGD PMID:16437207 RGD:10043375 NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670 		JBrowse link
G Ptgis prostaglandin I2 synthase treatment IMP RGD PMID:27834752 RGD:401960086 NCBI chr 3:155,928,564...155,964,228
Ensembl chr 3:155,916,412...155,965,451 		JBrowse link
G Ptn pleiotrophin IEP mRNA:increased expression:cerebral cortex, vasculature, macrophage (rat) RGD PMID:9570800 RGD:9831440 NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G Ptpn13 protein tyrosine phosphatase, non-receptor type 13 IEP mRNA,protein:increased expression:cerebral cortex: RGD PMID:18096138 RGD:4142863 NCBI chr14:6,108,202...6,282,619
Ensembl chr14:6,108,211...6,282,563 		JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 severity
treatment		 IEP
ISO
IDA		 protein:decreased phosphorylation, decreased expression:striatum (rat) RGD PMID:24198371 PMID:24198371 PMID:24198371 RGD:9835010, RGD:9835010, RGD:9835010 NCBI chr 1:97,620,638...97,681,186
Ensembl chr 1:97,620,642...97,679,882 		JBrowse link
G Rack1 receptor for activated C kinase 1 IDA RGD PMID:24007266 RGD:9588303 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Robo1 roundabout guidance receptor 1 disease_progression IEP
ISO		 protein:increased expression:hippocampus
protein:increased expression:brain, astrocyte		 RGD PMID:26764532 PMID:23473743 PMID:27686659 RGD:11573340, RGD:243048431, RGD:243048429 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 IEP protein:increased expression:brain, astrocyte RGD PMID:27686659 RGD:243048429 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Robo4 roundabout guidance receptor 4 IEP protein:increased expression:hippocampus RGD PMID:26764532 RGD:11573340 NCBI chr 8:37,119,953...37,133,887
Ensembl chr 8:37,119,988...37,132,519 		JBrowse link
G Rps6 ribosomal protein S6 IDA RGD PMID:26556340 RGD:11041643 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602 		JBrowse link
G Sema3e semaphorin 3E disease_progression IEP RGD PMID:30653356 RGD:155663383 NCBI chr 4:20,297,534...20,555,287
Ensembl chr 4:20,299,718...20,555,229 		JBrowse link
G Serpine1 serpin family E member 1 treatment IDA RGD PMID:26851971 RGD:11073692 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinf1 serpin family F member 1 treatment ISO human gene in a rat model RGD PMID:18624913 RGD:8613878 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 IEP mRNA:increased expression:hippocampus, pyramidal cell RGD PMID:15046873 RGD:1580967 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sin3a SIN3 transcription regulator family member A IDA RGD PMID:24063527 RGD:9495912 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Sirt6 sirtuin 6 IEP mRNA, protein:decreased expression:brain RGD PMID:23899523 RGD:9586062 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Slc12a2 solute carrier family 12 member 2 IEP RGD PMID:27798271 RGD:14398833 NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 IEP RGD PMID:23458738 RGD:9999193 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 IEP RGD PMID:23458738 RGD:9999193 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 IEP RGD PMID:23458738 RGD:9999193 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slit2 slit guidance ligand 2 IEP protein:increased expression:hippocampus
protein:increased expression:brain, astrocyte		 RGD PMID:26764532 PMID:27686659 RGD:11573340, RGD:243048429 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 IDA RGD PMID:24007266 RGD:9588303 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 treatment IEP RGD PMID:33081480 RGD:151347423 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Sod1 superoxide dismutase 1 treatment ISO human protein in a rat model
CTD Direct Evidence: therapeutic
human gene in a rat model		 CTD
RGD		 PMID:12629175 PMID:15829915 PMID:16538228 PMID:16868554 PMID:21531066 More... RGD:8655885, RGD:8655986 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11333366 PMID:30716316 RGD:27095883 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 exacerbates IDA
IMP		 RGD PMID:23764464 PMID:23884942 RGD:8694326, RGD:8694331 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tert telomerase reverse transcriptase treatment IDA RGD PMID:21914402 RGD:11038669 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tfpi tissue factor pathway inhibitor treatment ISO RGD PMID:18067952 RGD:11062087 NCBI chr 3:69,533,156...69,582,547
Ensembl chr 3:69,533,156...69,576,880 		JBrowse link
G Tia1 TIA1 cytotoxic granule-associated RNA binding protein IEP RGD PMID:16055272 RGD:10059581 NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586 		JBrowse link
G Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 IEP RGD PMID:10700014 RGD:1357161 NCBI chr 1:183,008,358...183,045,092
Ensembl chr 1:183,009,253...183,031,637 		JBrowse link
G Tnf tumor necrosis factor treatment IDA
IEP		 mRNA:increased expression:striatum,hippocampus: RGD PMID:24053818 PMID:11412877 RGD:7364868, RGD:13825263 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A treatment IEP mRNA:increased expression:striatum,hippocampus: RGD PMID:21868309 PMID:11412877 RGD:8661762, RGD:13825263 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Trpc6 transient receptor potential cation channel, subfamily C, member 6 treatment IDA
ISO		 RGD PMID:23435869 PMID:20811149 PMID:23043486 RGD:7247582, RGD:7247585, RGD:7247583 NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 IEP mRNA:increased expression:cerebral cortex RGD PMID:16777714 RGD:10003026 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 ISO RGD PMID:22284622 RGD:7175554 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
G Ucp2 uncoupling protein 2 treatment IDA RGD PMID:19772611 RGD:7204428 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
G Vwf von Willebrand factor treatment IDA RGD PMID:22771326 RGD:7207039 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 IEP RGD PMID:27798271 RGD:14398833 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905 		JBrowse link
G Wnk2 WNK lysine deficient protein kinase 2 IEP RGD PMID:27798271 RGD:14398833 NCBI chr17:15,503,672...15,612,479
Ensembl chr17:15,504,261...15,612,479 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 IEP RGD PMID:27798271 RGD:14398833 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 treatment IEP RGD PMID:19840223 RGD:2325713 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
Urinary Bladder Reperfusion Injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Elane elastase, neutrophil expressed treatment IMP RGD PMID:18165924 RGD:10450583 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 21128
    Nutritional and Metabolic Diseases 8237
      disease of metabolism 8237
        acquired metabolic disease 2535
          Reperfusion Injury 816
            Chronic Allograft Dysfunction + 28
            Gastric Reperfusion Injury 2
            Intestinal Reperfusion Injury 43
            Kidney Reperfusion Injury + 166
            Liver Reperfusion Injury 109
            Lung Reperfusion Injury + 27
            Myocardial Reperfusion Injury 290
            Ovary Reperfusion Injury 1
            Primary Graft Dysfunction 12
            Retina Reperfusion Injury 38
            Skeletal Muscle Reperfusion Injury 3
            Spinal Cord Reperfusion Injury 13
            Testis Reperfusion Injury 12
            Urinary Bladder Reperfusion Injury 1
            limb reperfusion injury 1
            transient cerebral ischemia + 241
Path 2
Term Annotations click to browse term
  disease 21128
    disease of anatomical entity 18211
      cardiovascular system disease 5404
        vascular disease 4006
          ischemia 1498
            Reperfusion Injury 816
              Chronic Allograft Dysfunction + 28
              Gastric Reperfusion Injury 2
              Intestinal Reperfusion Injury 43
              Kidney Reperfusion Injury + 166
              Liver Reperfusion Injury 109
              Lung Reperfusion Injury + 27
              Myocardial Reperfusion Injury 290
              Ovary Reperfusion Injury 1
              Primary Graft Dysfunction 12
              Retina Reperfusion Injury 38
              Skeletal Muscle Reperfusion Injury 3
              Spinal Cord Reperfusion Injury 13
              Testis Reperfusion Injury 12
              Urinary Bladder Reperfusion Injury 1
              limb reperfusion injury 1
              transient cerebral ischemia + 241
paths to the root