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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | RGD:734446 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of CITED1 mRNA | CTD | PMID:22206623 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | RGD:1344879 | 6480464 | Dihydrotestosterone results in increased expression of CITED1 mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:734446 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CITED1 mRNA | CTD | PMID:24058054 | 4,4'-sulfonyldiphenol | decreases expression | ISO | RGD:734446 | 6480464 | bis(4-hydroxyphenyl)sulfone results in decreased expression of CITED1 mRNA | CTD | PMID:30951980 | 5-aza-2'-deoxycytidine | increases expression | ISO | RGD:1344879 | 6480464 | Decitabine results in increased expression of CITED1 mRNA | CTD | PMID:21856257 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of CITED1 mRNA | CTD | PMID:23630614 | aflatoxin B1 | decreases methylation | ISO | RGD:1344879 | 6480464 | Aflatoxin B1 results in decreased methylation of CITED1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | decreases expression | ISO | RGD:1344879 | 6480464 | Tretinoin results in decreased expression of CITED1 mRNA | CTD | PMID:33167477 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CITED1 mRNA | CTD | PMID:16483693 | Aroclor 1254 | increases expression | ISO | RGD:1344879 | 6480464 | Chlorodiphenyl (54% Chlorine) results in increased expression of CITED1 mRNA | CTD | PMID:16934159 | benzo[a]pyrene | increases mutagenesis | ISO | RGD:1344879 | 6480464 | Benzo(a)pyrene results in increased mutagenesis of CITED1 gene | CTD | PMID:25435355 | benzo[a]pyrene | increases expression | ISO | RGD:1344879 | 6480464 | Benzo(a)pyrene results in increased expression of CITED1 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | affects methylation | ISO | RGD:1344879 | 6480464 | Benzo(a)pyrene affects the methylation of CITED1 5' UTR, Benzo(a)pyrene affects the methylation of CITED1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | decreases expression | ISO | RGD:734446 | 6480464 | Benzo(a)pyrene results in decreased expression of CITED1 mRNA | CTD | PMID:22228805 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:1344879 | 6480464 | Diethylhexyl Phthalate results in decreased expression of CITED1 mRNA | CTD | PMID:31163220 | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA | CTD | PMID:31199487 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of CITED1 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CITED1 mRNA | CTD | PMID:34947998 | bisphenol A | increases expression | ISO | RGD:734446 | 6480464 | bisphenol A results in increased expression of CITED1 mRNA | CTD | PMID:34585602 | bisphenol A | decreases expression | ISO | RGD:1344879 | 6480464 | bisphenol A results in decreased expression of CITED1 mRNA | CTD | PMID:31715268 | bisphenol A | decreases expression | ISO | RGD:734446 | 6480464 | bisphenol A results in decreased expression of CITED1 mRNA | CTD | PMID:30245210 | butanal | increases expression | ISO | RGD:1344879 | 6480464 | butyraldehyde results in increased expression of CITED1 mRNA | CTD | PMID:26079696 | Butylbenzyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA | CTD | PMID:31199487 | cadmium sulfate | multiple interactions | ISO | RGD:734446 | 6480464 | cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA] | CTD | PMID:28189605 | chlordecone | increases expression | ISO | RGD:734446 | 6480464 | Chlordecone results in increased expression of CITED1 mRNA | CTD | PMID:33711761 | chlorpyrifos | decreases expression | ISO | RGD:734446 | 6480464 | Chlorpyrifos results in decreased expression of CITED1 mRNA | CTD | PMID:32715474 | choline | multiple interactions | ISO | RGD:734446 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CITED1 gene | CTD | PMID:20938992 | cisplatin | multiple interactions | ISO | RGD:1344879 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of CITED1 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | RGD:1344879 | 6480464 | Cisplatin results in increased expression of CITED1 mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of CITED1 mRNA | CTD | PMID:24386269 | copper(II) sulfate | increases expression | ISO | RGD:1344879 | 6480464 | Copper Sulfate results in increased expression of CITED1 mRNA | CTD | PMID:19549813 | crocidolite asbestos | increases expression | ISO | RGD:734446 | 6480464 | Asbestos, Crocidolite results in increased expression of CITED1 mRNA | CTD | PMID:29279043 | dexamethasone | multiple interactions | ISO | RGD:734446 | 6480464 | [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA, cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA] | CTD | PMID:28189605 | dexamethasone | decreases expression | ISO | RGD:1344879 | 6480464 | Dexamethasone results in decreased expression of CITED1 mRNA | CTD | PMID:34742744 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of CITED1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA | CTD | PMID:31199487 | dibutyl phthalate | decreases expression | ISO | RGD:734446 | 6480464 | Dibutyl Phthalate results in decreased expression of CITED1 mRNA | CTD | PMID:17361019, PMID:21266533 | diethyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA | CTD | PMID:31199487 | diisobutyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA | CTD | PMID:31199487 | diisononyl phthalate | multiple interactions | EXP | | 6480464 | [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of CITED1 mRNA | CTD | PMID:31199487 | doxorubicin | decreases expression | ISO | RGD:1344879 | 6480464 | Doxorubicin results in decreased expression of CITED1 mRNA | CTD | PMID:29803840 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of CITED1 mRNA | CTD | PMID:29391264 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of CITED1 mRNA | CTD | PMID:24793618 | folic acid | multiple interactions | ISO | RGD:734446 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CITED1 gene | CTD | PMID:20938992 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CITED1 mRNA | CTD | PMID:33387578 | glycerol 2-phosphate | multiple interactions | ISO | RGD:734446 | 6480464 | [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA, cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA] | CTD | PMID:28189605 | L-ascorbic acid | multiple interactions | ISO | RGD:734446 | 6480464 | [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA, cadmium sulfate inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of CITED1 mRNA] | CTD | PMID:28189605 | L-methionine | multiple interactions | ISO | RGD:734446 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CITED1 gene | CTD | PMID:20938992 | manganese(II) chloride | decreases expression | EXP | | 6480464 | manganese chloride results in decreased expression of CITED1 mRNA | CTD | PMID:28801915 | methylisothiazolinone | increases expression | ISO | RGD:1344879 | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of CITED1 mRNA | CTD | PMID:31629900 | methylmercury chloride | decreases expression | ISO | RGD:1344879 | 6480464 | methylmercuric chloride results in decreased expression of CITED1 mRNA | CTD | PMID:28001369 | mifepristone | decreases expression | EXP | | 6480464 | Mifepristone results in decreased expression of CITED1 mRNA | CTD | PMID:25972201 | Muraglitazar | decreases expression | EXP | | 6480464 | muraglitazar results in decreased expression of CITED1 mRNA | CTD | PMID:21515302 | N-methyl-4-phenylpyridinium | decreases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of CITED1 mRNA | CTD | PMID:28801915 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CITED1 mRNA | CTD | PMID:28943392 | nitrofen | increases expression | EXP | | 6480464 | nitrofen results in increased expression of CITED1 mRNA | CTD | PMID:33484710 | paracetamol | increases expression | ISO | RGD:1344879 | 6480464 | Acetaminophen results in increased expression of CITED1 mRNA | CTD | PMID:26690555 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CITED1 mRNA | CTD | PMID:33387578 | pirinixic acid | multiple interactions | ISO | RGD:734446 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CITED1 mRNA | CTD | PMID:19710929 | pravastatin | decreases expression | ISO | RGD:734446 | 6480464 | Pravastatin results in decreased expression of CITED1 mRNA | CTD | PMID:27225895 | pravastatin | increases expression | EXP | | 6480464 | Pravastatin results in increased expression of CITED1 mRNA | CTD | PMID:27225895 | progesterone | increases expression | ISO | RGD:734446 | 6480464 | Progesterone results in increased expression of CITED1 mRNA | CTD | PMID:22238285 | propanal | increases expression | ISO | RGD:1344879 | 6480464 | propionaldehyde results in increased expression of CITED1 mRNA | CTD | PMID:26079696 | quercetin | decreases expression | ISO | RGD:1344879 | 6480464 | Quercetin results in decreased expression of CITED1 mRNA | CTD | PMID:15309432 | resveratrol | multiple interactions | ISO | RGD:1344879 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of CITED1 mRNA | CTD | PMID:23557933 | serpentine asbestos | increases expression | ISO | RGD:1344879 | 6480464 | Asbestos, Serpentine results in increased expression of CITED1 mRNA | CTD | PMID:18197826 | silver atom | increases expression | ISO | RGD:734446 | 6480464 | Silver results in increased expression of CITED1 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | ISO | RGD:734446 | 6480464 | Silver results in increased expression of CITED1 mRNA | CTD | PMID:27131904 | Tesaglitazar | decreases expression | EXP | | 6480464 | tesaglitazar results in decreased expression of CITED1 mRNA | CTD | PMID:21515302 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CITED1 mRNA | CTD | PMID:23411599, PMID:34492290 | thioacetamide | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of CITED1 mRNA | CTD | PMID:28943392 | triptonide | increases expression | ISO | RGD:734446 | 6480464 | triptonide results in increased expression of CITED1 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of CITED1 mRNA | CTD | PMID:21515302 | tunicamycin | increases expression | ISO | RGD:1344879 | 6480464 | Tunicamycin results in increased expression of CITED1 mRNA | CTD | PMID:22378314 | valproic acid | increases expression | ISO | RGD:1344879 | 6480464 | Valproic Acid results in increased expression of CITED1 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | RGD:1344879 | 6480464 | Valproic Acid affects the expression of CITED1 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | RGD:1344879 | 6480464 | Valproic Acid results in decreased expression of CITED1 mRNA | CTD | PMID:28001369 | |