Blk (BLK proto-oncogene, Src family tyrosine kinase) - Rat Genome Database

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Gene: Blk (BLK proto-oncogene, Src family tyrosine kinase) Rattus norvegicus
Analyze
Symbol: Blk
Name: BLK proto-oncogene, Src family tyrosine kinase
RGD ID: 1308859
Description: Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; peptidyl-tyrosine phosphorylation; and positive regulation of insulin secretion. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 11 and systemic lupus erythematosus. Orthologous to human BLK (BLK proto-oncogene, Src family tyrosine kinase); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; glypican signaling pathway; INTERACTS WITH aflatoxin B1; alpha-Zearalanol; decabromodiphenyl ether.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: B lymphoid kinase; B lymphoid tyrosine kinase; LOC364403; MGC112647; tyrosine-protein kinase Blk
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,802,701 - 41,841,004 (-)NCBIGRCr8
mRatBN7.21537,626,746 - 37,665,053 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1537,627,039 - 37,665,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1539,479,764 - 39,517,808 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01540,630,559 - 40,668,609 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,087,624 - 39,125,646 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01546,555,552 - 46,593,778 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1546,555,188 - 46,593,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01550,317,854 - 50,355,753 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41542,643,847 - 42,682,793 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11542,659,818 - 42,698,493 (-)NCBI
Celera1537,310,648 - 37,348,449 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. The effect of cardiac ischemic preconditioning on rat left ventricular gene expression profile. Canatan H Cell Biochem Funct. 2007 Jun 11;.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Replication of the association between the C8orf13-BLK region and systemic lupus erythematosus in a Japanese population. Ito I, etal., Arthritis Rheum. 2009 Feb;60(2):553-8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:876631   PMID:12477932   PMID:19667185   PMID:30356214  


Genomics

Comparative Map Data
Blk
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81541,802,701 - 41,841,004 (-)NCBIGRCr8
mRatBN7.21537,626,746 - 37,665,053 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1537,627,039 - 37,665,031 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1539,479,764 - 39,517,808 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01540,630,559 - 40,668,609 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01539,087,624 - 39,125,646 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01546,555,552 - 46,593,778 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1546,555,188 - 46,593,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01550,317,854 - 50,355,753 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41542,643,847 - 42,682,793 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11542,659,818 - 42,698,493 (-)NCBI
Celera1537,310,648 - 37,348,449 (-)NCBICelera
Cytogenetic Map15p12NCBI
BLK
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38811,494,387 - 11,564,599 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl811,486,894 - 11,564,599 (+)EnsemblGRCh38hg38GRCh38
GRCh37811,351,896 - 11,422,108 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36811,388,930 - 11,459,517 (+)NCBINCBI36Build 36hg18NCBI36
Build 34811,388,929 - 11,459,516NCBI
Celera810,480,897 - 10,551,454 (+)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef810,282,885 - 10,353,426 (+)NCBIHuRef
CHM1_1811,416,813 - 11,487,683 (+)NCBICHM1_1
T2T-CHM13v2.088,175,675 - 8,245,838 (-)NCBIT2T-CHM13v2.0
Blk
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391463,610,286 - 63,654,636 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1463,610,285 - 63,654,486 (-)EnsemblGRCm39 Ensembl
GRCm381463,372,837 - 63,417,187 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1463,372,836 - 63,417,037 (-)EnsemblGRCm38mm10GRCm38
MGSCv371463,991,674 - 64,036,024 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361462,326,947 - 62,371,297 (-)NCBIMGSCv36mm8
Celera1461,138,348 - 61,182,625 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.25NCBI
Blk
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540352,832,604 - 52,874,264 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540352,825,397 - 52,874,007 (+)NCBIChiLan1.0ChiLan1.0
BLK
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2727,961,701 - 28,032,048 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan183,988,006 - 4,058,396 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v087,637,680 - 7,708,914 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
BLK
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12526,336,253 - 26,357,494 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2526,336,892 - 26,358,015 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2526,989,229 - 27,064,576 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02526,487,019 - 26,562,216 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2526,487,603 - 26,562,224 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12526,439,922 - 26,514,938 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02526,336,943 - 26,412,007 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02526,488,713 - 26,563,761 (-)NCBIUU_Cfam_GSD_1.0
Blk
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049435,339,527 - 5,357,038 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366753,229,154 - 3,246,292 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366753,228,982 - 3,246,617 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BLK
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1414,688,943 - 14,745,947 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11414,688,489 - 14,745,946 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21415,895,128 - 15,934,019 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BLK
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.187,547,200 - 7,618,645 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl87,547,299 - 7,569,188 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605234,810,867 - 34,883,078 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Blk
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475825,129,853 - 25,181,761 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475825,129,922 - 25,180,180 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Blk
225 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:274
Count of miRNA genes:180
Interacting mature miRNAs:199
Transcripts:ENSRNOT00000015021
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

Markers in Region
D15Rat119  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81541,807,938 - 41,808,150 (+)Marker Load Pipeline
mRatBN7.21537,631,983 - 37,632,195 (+)MAPPERmRatBN7.2
Rnor_6.01546,560,523 - 46,560,734NCBIRnor6.0
Rnor_5.01550,322,825 - 50,323,036UniSTSRnor5.0
RGSC_v3.41542,649,228 - 42,649,440RGDRGSC3.4
RGSC_v3.41542,649,229 - 42,649,440UniSTSRGSC3.4
RGSC_v3.11542,664,928 - 42,665,140RGD
Celera1537,315,611 - 37,315,822UniSTS
SHRSP x BN Map1532.3898UniSTS
SHRSP x BN Map1532.3898RGD
Cytogenetic Map15p12UniSTS
RH131524  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21537,626,771 - 37,626,965 (+)MAPPERmRatBN7.2
Rnor_6.01546,301,761 - 46,301,954NCBIRnor6.0
Rnor_5.01550,066,555 - 50,066,748UniSTSRnor5.0
RGSC_v3.41542,643,606 - 42,643,799UniSTSRGSC3.4
Celera1537,310,407 - 37,310,600UniSTS
RH 3.4 Map15285.2UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 45 76 87 86 55 25 55 6 194 91 56 31 54 31

Sequence


Ensembl Acc Id: ENSRNOT00000015021   ⟹   ENSRNOP00000015021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1537,627,039 - 37,665,031 (-)Ensembl
Rnor_6.0 Ensembl1546,555,188 - 46,593,653 (-)Ensembl
RefSeq Acc Id: NM_001025751   ⟹   NP_001020922
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,802,968 - 41,840,982 (-)NCBI
mRatBN7.21537,627,013 - 37,665,031 (-)NCBI
Rnor_6.01546,555,552 - 46,593,570 (-)NCBI
Rnor_5.01550,317,854 - 50,355,753 (-)NCBI
RGSC_v3.41542,643,847 - 42,682,793 (-)RGD
Celera1537,310,648 - 37,348,449 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252188   ⟹   XP_006252250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,802,701 - 41,841,004 (-)NCBI
mRatBN7.21537,626,746 - 37,665,053 (-)NCBI
Rnor_6.01546,555,552 - 46,593,778 (-)NCBI
Rnor_5.01550,317,854 - 50,355,753 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093550   ⟹   XP_038949478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81541,802,701 - 41,813,892 (-)NCBI
mRatBN7.21537,626,746 - 37,637,948 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001020922 (Get FASTA)   NCBI Sequence Viewer  
  XP_006252250 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949478 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98683 (Get FASTA)   NCBI Sequence Viewer  
  EDL85321 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000015021
  ENSRNOP00000015021.4
RefSeq Acc Id: NP_001020922   ⟸   NM_001025751
- UniProtKB: Q4KM97 (UniProtKB/TrEMBL),   F7EWL4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252250   ⟸   XM_006252188
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000015021   ⟸   ENSRNOT00000015021
RefSeq Acc Id: XP_038949478   ⟸   XM_039093550
- Peptide Label: isoform X2
Protein Domains
Protein kinase   SH2   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM97-F1-model_v2 AlphaFold Q4KM97 1-499 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308859 AgrOrtholog
BioCyc Gene G2FUF-13429 BioCyc
Ensembl Genes ENSRNOG00000010798 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015021 ENTREZGENE
  ENSRNOT00000015021.7 UniProtKB/TrEMBL
Gene3D-CATH 3.30.505.10 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  SH3 Domains UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7385175 IMAGE-MGC_LOAD
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Non-receptor_tyrosine_kinases UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser-Thr/Tyr-Pkinase UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
  Tyr_Pkinase_cat_dom UniProtKB/TrEMBL
KEGG Report rno:364403 UniProtKB/TrEMBL
MGC_CLONE MGC:112647 IMAGE-MGC_LOAD
NCBI Gene 364403 ENTREZGENE
PANTHER TYROSINE-PROTEIN KINASE UniProtKB/TrEMBL
Pfam Pkinase_Tyr UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3_1 UniProtKB/TrEMBL
PharmGKB BLK RGD
PhenoGen Blk PhenoGen
PRINTS SH2DOMAIN UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010798 RatGTEx
SMART SH2 UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SSF55550 UniProtKB/TrEMBL
UniProt F7EWL4 ENTREZGENE, UniProtKB/TrEMBL
  Q4KM97 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-09 Blk  BLK proto-oncogene, Src family tyrosine kinase  Blk  B lymphoid tyrosine kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Blk  B lymphoid tyrosine kinase  Blk  B lymphoid kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Blk  B lymphoid kinase  Blk_predicted  B lymphoid kinase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Blk_predicted  B lymphoid kinase (predicted)      Symbol and Name status set to approved 70820 APPROVED