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Gene: Cysltr2 (cysteinyl leukotriene receptor 2) Rattus norvegicus
Symbol: Cysltr2
Name: cysteinyl leukotriene receptor 2
RGD ID: 619797
Description: Predicted to have G protein-coupled peptide receptor activity and cysteinyl leukotriene receptor activity. Involved in positive regulation of ERK1 and ERK2 cascade; positive regulation of angiogenesis; and positive regulation of cell death. Predicted to localize to integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CYSLTR2 (cysteinyl leukotriene receptor 2); PARTICIPATES IN endothelin signaling pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH ammonium chloride; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cyslt2; cysteinyl leukotriene CysLT2 receptor; RSBPT32
Homo sapiens (human) : CYSLTR2 (cysteinyl leukotriene receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Cysltr2 (cysteinyl leukotriene receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cysltr2 (cysteinyl leukotriene receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CYSLTR2 (cysteinyl leukotriene receptor 2)
Canis lupus familiaris (dog) : CYSLTR2 (cysteinyl leukotriene receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cysltr2 (cysteinyl leukotriene receptor 2)
Sus scrofa (pig) : CYSLTR2 (cysteinyl leukotriene receptor 2)
Chlorocebus sabaeus (African green monkey) : CYSLTR2 (cysteinyl leukotriene receptor 2)
Heterocephalus glaber (naked mole-rat) : Cysltr2 (cysteinyl leukotriene receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01554,903,290 - 54,941,742 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1554,905,274 - 54,906,203 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01558,626,639 - 58,627,568 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41553,647,500 - 53,648,429 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11553,663,279 - 53,664,209 (-)NCBI
Celera1547,842,400 - 47,878,749 (-)NCBICelera
Cytogenetic Map15p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cysltr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619797
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.