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Gene: Atg16l1 (autophagy related 16-like 1) Rattus norvegicus

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Symbol:

Atg16l1

Name:

autophagy related 16-like 1

RGD ID:

1310631

Description:

Predicted to enable GTPase binding activity; identical protein binding activity; and protein-membrane adaptor activity. Involved in dendrite arborization and negative regulation of dendrite extension. Is active in glutamatergic synapse. Human ortholog(s) of this gene implicated in inflammatory bowel disease 10. Orthologous to human ATG16L1 (autophagy related 16 like 1); PARTICIPATES IN autophagy pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

APG16 autophagy 16-like; APG16 autophagy 16-like (S. cerevisiae); Apg16l; ATG16 autophagy related 16-like 1; ATG16 autophagy related 16-like 1 (S. cerevisiae); autophagy related 16-like 1 (S. cerevisiae); autophagy-related 16-like 1; autophagy-related 16-like 1 (yeast); autophagy-related protein 16-1; LOC363278; WD repeat domain 30; Wdr30

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ATG16L1 (autophagy related 16 like 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Atg16l1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Atg16l1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ATG16L1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ATG16L1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Atg16l1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ATG16L1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ATG16L1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Atg16l1 (autophagy related 16 like 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	ATG16L1 (autophagy related 16 like 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Atg16l1 (autophagy related 16 like 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	atg16l1 (ATG16 autophagy related 16-like 1 (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Atg16	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	atg-16.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	atg-16.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	atg16l1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Atg16l1^em8Rrrc

Genetic Models:

F344-Atg16l1^em8Rrrc

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	95,869,839 - 95,905,354 (+)	NCBI		GRCr8
mRatBN7.2	9	88,420,737 - 88,457,530 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	88,422,038 - 88,457,529 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	96,846,724 - 96,882,032 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	101,982,902 - 102,018,214 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	100,350,405 - 100,385,741 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	94,879,876 - 94,915,231 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	94,879,745 - 94,915,228 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	94,599,174 - 94,634,551 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	86,712,122 - 86,747,370 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	86,895,541 - 86,929,665 (+)	NCBI
Celera	9	85,830,765 - 85,865,957 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

JBrowse:

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Model

Annotation Click to see Annotation Detail View

RGD Manual Disease Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	Cardiomegaly	treatment	IEP		11561938		RGD
Atg16l1	Rat	Liver Reperfusion Injury	ameliorates	ISO	RGD:1553543	329902072		RGD

Imported Disease Annotations - ClinVar

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	inflammatory bowel disease 10		ISO	RGD:1321647	8554872	ClinVar Annotator: match by term: Inflammatory bowel disease 10 \| ClinVar Annotator: match by term: more ...	ClinVar	PMID:17200669\|PMID:17435756\|PMID:18438405\|PMID:18852889\|PMID:19337756\|PMID:24553140\|PMID:25741868\|PMID:27273576\|PMID:30166421
Atg16l1	Rat	Joubert syndrome 22		ISO	RGD:1321647	8554872	ClinVar Annotator: match by term: Joubert syndrome 22	ClinVar	PMID:28492532
Atg16l1	Rat	Perlman syndrome		ISO	RGD:1321647	8554872	ClinVar Annotator: match by term: Perlman syndrome	ClinVar	PMID:28492532

Imported Disease Annotations - CTD

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	Crohn's disease		ISO	RGD:1321647	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:17435756\|PMID:18438406
Atg16l1	Rat	inflammatory bowel disease		ISO	RGD:1321647	11554173	CTD Direct Evidence: marker/mechanism	CTD	PMID:26192919
Atg16l1	Rat	inflammatory bowel disease 10		ISO	RGD:1321647	11554173	CTD Direct Evidence: marker/mechanism	CTD
Atg16l1	Rat	Zika fever		ISO	RGD:1321647	11554173	CTD Direct Evidence: therapeutic	CTD	PMID:28694387

Imported Disease Annotations - MGI

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	inflammatory bowel disease 10		ISS	RGD:1553543	13592920	OMIM:611081	MouseDO

Imported Disease Annotations - OMIM

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	inflammatory bowel disease 10		ISO	RGD:1321647	7240710		OMIM

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	RGD:1553543	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATG16L1 mRNA	CTD	PMID:36331819
Atg16l1	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	RGD:1553543	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG16L1 mRNA	CTD	PMID:22206623
Atg16l1	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	RGD:1553543	6480464	Tetrachlorodibenzodioxin affects the expression of ATG16L1 mRNA	CTD	PMID:21570461
Atg16l1	Rat	2,3,7,8-tetrachlorodibenzodioxine	decreases expression	EXP		6480464	Tetrachlorodibenzodioxin results in decreased expression of ATG16L1 mRNA	CTD	PMID:34747641
Atg16l1	Rat	2,4-dinitrotoluene	affects expression	EXP		6480464	2,4-dinitrotoluene affects the expression of ATG16L1 mRNA	CTD	PMID:21346803
Atg16l1	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2,6-dinitrotoluene affects the expression of ATG16L1 mRNA	CTD	PMID:21346803
Atg16l1	Rat	2-hydroxypropanoic acid	decreases expression	ISO	RGD:1321647	6480464	Lactic Acid results in decreased expression of ATG16L1 mRNA	CTD	PMID:30851411
Atg16l1	Rat	2-methylcholine	affects expression	ISO	RGD:1321647	6480464	beta-methylcholine affects the expression of ATG16L1 mRNA	CTD	PMID:21179406
Atg16l1	Rat	2-palmitoylglycerol	increases expression	ISO	RGD:1321647	6480464	2-palmitoylglycerol results in increased expression of ATG16L1 mRNA	CTD	PMID:37199045
Atg16l1	Rat	3,3',4,4'-tetrachlorobiphenyl	multiple interactions	ISO	RGD:1553543	6480464	3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of ATG16L1 mRNA]	CTD	PMID:19467301
Atg16l1	Rat	3,4-methylenedioxymethamphetamine	decreases expression	ISO	RGD:1553543	6480464	N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of ATG16L1 mRNA	CTD	PMID:26251327
Atg16l1	Rat	3-chloropropane-1,2-diol	increases expression	EXP		6480464	alpha-Chlorohydrin results in increased expression of ATG16L1 protein	CTD	PMID:34915118
Atg16l1	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	RGD:1553543	6480464	bisphenol S results in decreased expression of ATG16L1 mRNA	CTD	PMID:29741722
Atg16l1	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	RGD:1553543	6480464	bisphenol S results in increased expression of ATG16L1 mRNA	CTD	PMID:39298647
Atg16l1	Rat	acrolein	multiple interactions	ISO	RGD:1321647	6480464	Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG16L1 protein]	CTD	PMID:30205151
Atg16l1	Rat	acrolein	increases expression	ISO	RGD:1321647	6480464	Acrolein results in increased expression of ATG16L1 protein	CTD	PMID:30205151
Atg16l1	Rat	aflatoxin B1	increases methylation	ISO	RGD:1321647	6480464	Aflatoxin B1 results in increased methylation of ATG16L1 gene	CTD	PMID:27153756
Atg16l1	Rat	aristolochic acid A	increases expression	ISO	RGD:1321647	6480464	aristolochic acid I results in increased expression of ATG16L1 mRNA	CTD	PMID:33212167
Atg16l1	Rat	arsane	multiple interactions	ISO	RGD:1321647	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Atg16l1	Rat	arsenic atom	multiple interactions	ISO	RGD:1321647	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Atg16l1	Rat	atrazine	decreases expression	ISO	RGD:1553543	6480464	Atrazine results in decreased expression of ATG16L1 mRNA	CTD	PMID:30360616
Atg16l1	Rat	atrazine	multiple interactions	ISO	RGD:1553543	6480464	Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA]	CTD	PMID:30360616
Atg16l1	Rat	bis(2-ethylhexyl) phthalate	multiple interactions	ISO	RGD:1321647	6480464	[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in decreased methylation of ATG16L1 more ...	CTD	PMID:33872906
Atg16l1	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	RGD:1553543	6480464	Diethylhexyl Phthalate results in decreased expression of ATG16L1 mRNA	CTD	PMID:34319233
Atg16l1	Rat	bis(2-ethylhexyl) phthalate	decreases methylation	EXP		6480464	Diethylhexyl Phthalate results in decreased methylation of ATG16L1 gene	CTD	PMID:33923623
Atg16l1	Rat	bisphenol A	decreases expression	ISO	RGD:1553543	6480464	bisphenol A results in decreased expression of ATG16L1 mRNA	CTD	PMID:29741722
Atg16l1	Rat	bisphenol A	increases methylation	ISO	RGD:1321647	6480464	bisphenol A results in increased methylation of ATG16L1 gene	CTD	PMID:31601247
Atg16l1	Rat	bisphenol A	multiple interactions	ISO	RGD:1321647	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of ATG16L1 gene	CTD	PMID:31601247
Atg16l1	Rat	bisphenol A	decreases expression	EXP		6480464	bisphenol A results in decreased expression of ATG16L1 mRNA	CTD	PMID:32145629\|PMID:34947998
Atg16l1	Rat	bisphenol A	increases expression	ISO	RGD:1553543	6480464	bisphenol A results in increased expression of ATG16L1 mRNA	CTD	PMID:33221593
Atg16l1	Rat	bisphenol A	decreases expression	ISO	RGD:1321647	6480464	bisphenol A results in decreased expression of ATG16L1 protein	CTD	PMID:33376534
Atg16l1	Rat	bisphenol A	affects expression	EXP		6480464	bisphenol A affects the expression of ATG16L1 mRNA	CTD	PMID:25181051
Atg16l1	Rat	Brodifacoum	increases expression	EXP		6480464	bromfenacoum results in increased expression of ATG16L1 protein	CTD	PMID:28903499
Atg16l1	Rat	C60 fullerene	increases expression	EXP		6480464	fullerene C60 results in increased expression of ATG16L1 mRNA	CTD	PMID:19167457
Atg16l1	Rat	cadmium dichloride	multiple interactions	ISO	RGD:1553543	6480464	ATG16L1 protein affects the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]	CTD	PMID:29218509
Atg16l1	Rat	cadmium dichloride	decreases expression	ISO	RGD:1321647	6480464	Cadmium Chloride results in decreased expression of ATG16L1 mRNA	CTD	PMID:38382870
Atg16l1	Rat	cadmium dichloride	affects response to substance	EXP		6480464	ATG16L1 protein affects the susceptibility to Cadmium Chloride	CTD	PMID:29218509
Atg16l1	Rat	cadmium dichloride	multiple interactions	EXP		6480464	[ATG16L1 protein affects the susceptibility to Cadmium Chloride] which results in increased cleavage of CASP3 more ...	CTD	PMID:29218509
Atg16l1	Rat	capsaicin	decreases expression	EXP		6480464	Capsaicin results in decreased expression of ATG16L1 mRNA	CTD	PMID:20349343
Atg16l1	Rat	copper(II) sulfate	increases expression	ISO	RGD:1321647	6480464	Copper Sulfate results in increased expression of ATG16L1 mRNA	CTD	PMID:19549813
Atg16l1	Rat	coumarin	affects phosphorylation	ISO	RGD:1321647	6480464	coumarin affects the phosphorylation of ATG16L1 protein	CTD	PMID:35688186
Atg16l1	Rat	cyclosporin A	increases expression	ISO	RGD:1321647	6480464	Cyclosporine results in increased expression of ATG16L1 mRNA	CTD	PMID:25562108
Atg16l1	Rat	Dibutyl phosphate	affects expression	ISO	RGD:1321647	6480464	di-n-butylphosphoric acid affects the expression of ATG16L1 mRNA	CTD	PMID:37042841
Atg16l1	Rat	dorsomorphin	multiple interactions	ISO	RGD:1321647	6480464	dorsomorphin inhibits the reaction [sodium arsenite results in increased phosphorylation of ATG16L1 protein]	CTD	PMID:38101599
Atg16l1	Rat	doxorubicin	multiple interactions	ISO	RGD:1321647	6480464	PQQ Cofactor inhibits the reaction [Doxorubicin results in increased expression of ATG16L1 protein]	CTD	PMID:31226464
Atg16l1	Rat	doxorubicin	decreases expression	ISO	RGD:1321647	6480464	Doxorubicin results in decreased expression of ATG16L1 mRNA	CTD	PMID:29803840
Atg16l1	Rat	doxorubicin	increases expression	ISO	RGD:1321647	6480464	Doxorubicin results in increased expression of ATG16L1 protein	CTD	PMID:31226464
Atg16l1	Rat	epoxiconazole	decreases expression	ISO	RGD:1553543	6480464	epoxiconazole results in decreased expression of ATG16L1 mRNA	CTD	PMID:35436446
Atg16l1	Rat	ethanol	affects splicing	ISO	RGD:1553543	6480464	Ethanol affects the splicing of ATG16L1 mRNA	CTD	PMID:30319688
Atg16l1	Rat	fenthion	decreases expression	ISO	RGD:1553543	6480464	Fenthion results in decreased expression of ATG16L1 mRNA	CTD	PMID:34813904
Atg16l1	Rat	folic acid	multiple interactions	ISO	RGD:1553543	6480464	[1,2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ATG16L1 mRNA	CTD	PMID:22206623
Atg16l1	Rat	FR900359	affects phosphorylation	ISO	RGD:1321647	6480464	FR900359 affects the phosphorylation of ATG16L1 protein	CTD	PMID:37730182
Atg16l1	Rat	fulvestrant	increases methylation	ISO	RGD:1321647	6480464	Fulvestrant results in increased methylation of ATG16L1 gene	CTD	PMID:31601247
Atg16l1	Rat	fulvestrant	multiple interactions	ISO	RGD:1321647	6480464	[bisphenol A co-treated with Fulvestrant] results in increased methylation of ATG16L1 gene	CTD	PMID:31601247
Atg16l1	Rat	galangin	multiple interactions	ISO	RGD:1321647	6480464	[ATG16L1 mutant form co-treated with galangin] results in decreased activity of CASP3 protein; LY2109761 inhibits more ...	CTD	PMID:25268046
Atg16l1	Rat	galangin	increases expression	ISO	RGD:1321647	6480464	galangin results in increased expression of ATG16L1 mRNA; galangin results in increased expression of ATG16L1 more ...	CTD	PMID:25268046
Atg16l1	Rat	gentamycin	decreases expression	EXP		6480464	Gentamicins results in decreased expression of ATG16L1 mRNA	CTD	PMID:33387578
Atg16l1	Rat	lycopene	multiple interactions	ISO	RGD:1553543	6480464	Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA]	CTD	PMID:30360616
Atg16l1	Rat	manganese atom	multiple interactions	ISO	RGD:1321647	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Atg16l1	Rat	manganese(0)	multiple interactions	ISO	RGD:1321647	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Atg16l1	Rat	manganese(II) chloride	multiple interactions	ISO	RGD:1321647	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:39836092
Atg16l1	Rat	melphalan	increases expression	ISO	RGD:1321647	6480464	Melphalan results in increased expression of ATG16L1 mRNA	CTD	PMID:22363485
Atg16l1	Rat	methamphetamine	increases expression	EXP		6480464	Methamphetamine results in increased expression of ATG16L1 mRNA	CTD	PMID:32676729
Atg16l1	Rat	methotrexate	increases expression	ISO	RGD:1321647	6480464	Methotrexate results in increased expression of ATG16L1 mRNA	CTD	PMID:21678067
Atg16l1	Rat	mono(2-ethylhexyl) phthalate	multiple interactions	ISO	RGD:1321647	6480464	[Diethylhexyl Phthalate results in increased abundance of mono-(2-ethylhexyl)phthalate] which results in decreased methylation of ATG16L1 more ...	CTD	PMID:33872906
Atg16l1	Rat	N-acetyl-L-cysteine	multiple interactions	ISO	RGD:1321647	6480464	Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG16L1 protein]	CTD	PMID:30205151
Atg16l1	Rat	paracetamol	affects expression	ISO	RGD:1553543	6480464	Acetaminophen affects the expression of ATG16L1 mRNA	CTD	PMID:17562736
Atg16l1	Rat	paracetamol	increases expression	ISO	RGD:1321647	6480464	Acetaminophen results in increased expression of ATG16L1 mRNA	CTD	PMID:22230336
Atg16l1	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	RGD:1553543	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ATG16L1 mRNA	CTD	PMID:36331819
Atg16l1	Rat	pyrroloquinoline quinone	multiple interactions	ISO	RGD:1321647	6480464	PQQ Cofactor inhibits the reaction [Doxorubicin results in increased expression of ATG16L1 protein]	CTD	PMID:31226464
Atg16l1	Rat	rac-lactic acid	decreases expression	ISO	RGD:1321647	6480464	Lactic Acid results in decreased expression of ATG16L1 mRNA	CTD	PMID:30851411
Atg16l1	Rat	rotenone	decreases expression	ISO	RGD:1553543	6480464	Rotenone results in decreased expression of ATG16L1 mRNA	CTD	PMID:23186747
Atg16l1	Rat	sodium arsenite	increases expression	ISO	RGD:1553543	6480464	sodium arsenite results in increased expression of ATG16L1 mRNA	CTD	PMID:30097599
Atg16l1	Rat	sodium arsenite	increases phosphorylation	ISO	RGD:1321647	6480464	sodium arsenite results in increased phosphorylation of ATG16L1 protein	CTD	PMID:38101599
Atg16l1	Rat	sodium arsenite	multiple interactions	ISO	RGD:1321647	6480464	[[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ...	CTD	PMID:38101599\|PMID:39836092
Atg16l1	Rat	sodium arsenite	increases phosphorylation	ISO	RGD:1553543	6480464	sodium arsenite results in increased phosphorylation of ATG16L1 protein	CTD	PMID:38101599\|PMID:38579892
Atg16l1	Rat	sodium arsenite	multiple interactions	ISO	RGD:1553543	6480464	[sodium arsenite co-treated with Dietary Fats] results in increased expression of ATG16L1 mRNA	CTD	PMID:30097599
Atg16l1	Rat	Soman	increases expression	EXP		6480464	Soman results in increased expression of ATG16L1 mRNA	CTD	PMID:19281266
Atg16l1	Rat	thioacetamide	increases expression	EXP		6480464	Thioacetamide results in increased expression of ATG16L1 mRNA	CTD	PMID:23411599\|PMID:34492290
Atg16l1	Rat	thiram	increases expression	ISO	RGD:1321647	6480464	Thiram results in increased expression of ATG16L1 mRNA	CTD	PMID:38568856
Atg16l1	Rat	trichloroethene	decreases methylation	EXP		6480464	Trichloroethylene results in decreased methylation of ATG16L1 gene	CTD	PMID:27618143
Atg16l1	Rat	triptonide	increases expression	ISO	RGD:1553543	6480464	triptonide results in increased expression of ATG16L1 mRNA	CTD	PMID:33045310
Atg16l1	Rat	trovafloxacin	increases expression	ISO	RGD:1321647	6480464	trovafloxacin results in increased expression of ATG16L1 mRNA	CTD	PMID:33609687
Atg16l1	Rat	trovafloxacin	multiple interactions	ISO	RGD:1321647	6480464	[trovafloxacin co-treated with TNF protein] results in increased expression of ATG16L1 mRNA	CTD	PMID:33609687
Atg16l1	Rat	valproic acid	increases expression	ISO	RGD:1321647	6480464	Valproic Acid results in increased expression of ATG16L1 mRNA	CTD	PMID:29154799

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	autophagosome assembly	involved_in	IBA	MGI:1924290\|PANTHER:PTN000459085\|UniProtKB:Q676U5\|WB:WBGene00019427\|dictyBase:DDB_G0275323	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Atg16l1	Rat	autophagosome assembly	involved_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	autophagosome assembly	involved_in	IEA	InterPro:IPR045160	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Atg16l1	Rat	autophagosome assembly	involved_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	autophagosome assembly	involved_in	ISO	RGD:1553543	1624291	PMID:11266458	RGD	PMID:11266458
Atg16l1	Rat	autophagosome assembly	involved_in	ISO	RGD:1321647	1624291	PMID:30778222	RGD	PMID:30778222
Atg16l1	Rat	axonal transport	involved_in	ISO	RGD:1553543	1624291	PMID:32210230	RGD	PMID:32210230
Atg16l1	Rat	axonal transport	involved_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	C-terminal protein lipidation	involved_in	ISO	RGD:1321647	1624291	PMID:33586810	RGD	PMID:33586810
Atg16l1	Rat	corpus callosum development	acts_upstream_of_or_within	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	corpus callosum development	acts_upstream_of_or_within	ISO	RGD:1553543	1624291	MGI:4432181 PMID:29078390	RGD	PMID:29078390
Atg16l1	Rat	defense response to virus	involved_in	ISO	RGD:1553543	1624291	PMID:33586810	RGD	PMID:33586810
Atg16l1	Rat	defense response to virus	involved_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	dendrite arborization		IMP		407532699		RGD
Atg16l1	Rat	hippocampus development	acts_upstream_of_or_within	ISO	RGD:1553543	1624291	MGI:4432181 PMID:29078390	RGD	PMID:29078390
Atg16l1	Rat	hippocampus development	acts_upstream_of_or_within	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	macroautophagy	involved_in	ISO	RGD:1321647	1624291	PMID:29317426, PMID:33586810	RGD	PMID:29317426\|PMID:33586810
Atg16l1	Rat	macroautophagy	involved_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	macroautophagy	involved_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	macroautophagy	involved_in	ISO	RGD:1553543	1624291	PMID:11266458	RGD	PMID:11266458
Atg16l1	Rat	microautophagy	involved_in	ISO	RGD:1321647	1624291	PMID:29317426, PMID:33586810	RGD	PMID:29317426\|PMID:33586810
Atg16l1	Rat	microautophagy	involved_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	microautophagy	involved_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	microautophagy	involved_in	ISO	RGD:1553543	1624291	PMID:33586810	RGD	PMID:33586810
Atg16l1	Rat	negative regulation of dendrite extension		IMP		407532699		RGD
Atg16l1	Rat	negative stranded viral RNA replication	acts_upstream_of_or_within	ISO	RGD:1553543	1624291	PMID:24550300	RGD	PMID:24550300
Atg16l1	Rat	negative stranded viral RNA replication	acts_upstream_of_or_within	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	positive regulation of autophagy	involved_in	ISO	RGD:1553543	1624291	PMID:30208760	RGD	PMID:30208760
Atg16l1	Rat	positive regulation of autophagy	involved_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	protein lipidation involved in autophagosome assembly	acts_upstream_of_or_within	ISO	RGD:1553543	1624291	PMID:24954904	RGD	PMID:24954904
Atg16l1	Rat	protein localization to phagophore assembly site	involved_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	protein localization to phagophore assembly site	involved_in	ISO	RGD:1321647	1624291	PMID:32960676	RGD	PMID:32960676
Atg16l1	Rat	protein localization to phagophore assembly site	acts_upstream_of_or_within	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	protein localization to phagophore assembly site	acts_upstream_of_or_within	ISO	RGD:1553543	1624291	PR:Q80W47 PMID:24954904	RGD	PMID:24954904
Atg16l1	Rat	xenophagy	acts_upstream_of_or_within	ISO	RGD:1553543	1624291	PR:Q80W47 PMID:24954904	RGD	PMID:24954904
Atg16l1	Rat	xenophagy	acts_upstream_of_or_within	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	Atg12-Atg5-Atg16 complex	part_of	IBA	MGI:1920933\|MGI:1924290\|PANTHER:PTN000459085\|UniProtKB:Q676U5\|UniProtKB:Q8NAA4	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Atg16l1	Rat	Atg12-Atg5-Atg16 complex	part_of	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	Atg12-Atg5-Atg16 complex	part_of	ISO	RGD:1553543	1624291	PMID:12665549	RGD	PMID:12665549
Atg16l1	Rat	Atg12-Atg5-Atg16 complex	part_of	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	Atg12-Atg5-Atg16 complex	part_of	ISO	RGD:1321647	1624291	PMID:23202584, PMID:29317426, PMID:33586810	RGD	PMID:23202584\|PMID:29317426\|PMID:33586810
Atg16l1	Rat	autophagosome	located_in	ISO	RGD:1553543	1624291	PMID:12665549	RGD	PMID:12665549
Atg16l1	Rat	autophagosome	located_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	autophagosome membrane	is_active_in	IBA	MGI:1924290\|PANTHER:PTN000459085\|UniProtKB:Q676U5	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Atg16l1	Rat	autophagosome membrane	located_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	autophagosome membrane	located_in	ISO	RGD:1553543	1624291	PMID:21220506	RGD	PMID:21220506
Atg16l1	Rat	autophagosome membrane	is_active_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	autophagosome membrane	is_active_in	ISO	RGD:1321647	1624291	PMID:29317426	RGD	PMID:29317426
Atg16l1	Rat	axon	located_in	IEA	GO:0098930	1600115	GO_REF:0000108	GOC	GO_REF:0000108
Atg16l1	Rat	axoneme	located_in	ISO	RGD:1553543	1624291	PMID:24089209	RGD	PMID:24089209
Atg16l1	Rat	axoneme	located_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	cytoplasm	located_in	ISO	RGD:1553543	1624291	PMID:33087875	RGD	PMID:33087875
Atg16l1	Rat	cytoplasm	located_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	endolysosome membrane	is_active_in	ISO	RGD:1321647	1624291	PMID:29317426	RGD	PMID:29317426
Atg16l1	Rat	endolysosome membrane	is_active_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	glutamatergic synapse	is_active_in	IDA		405650312	PMID:28231469	SynGO
Atg16l1	Rat	glutamatergic synapse	is_active_in	ISO	RGD:1553543	1624291	PMID:32210230	RGD	PMID:32210230
Atg16l1	Rat	glutamatergic synapse	is_active_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	phagophore assembly site membrane	is_active_in	IBA	MGI:1920933\|MGI:1924290\|PANTHER:PTN000459085	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Atg16l1	Rat	phagophore assembly site membrane	located_in	ISO	RGD:1321647	1624291	PMID:32960676	RGD	PMID:32960676
Atg16l1	Rat	phagophore assembly site membrane	located_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	phagophore assembly site membrane	located_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	phagophore assembly site membrane	located_in	ISO	RGD:1553543	1624291	PMID:12665549	RGD	PMID:12665549
Atg16l1	Rat	sperm midpiece	located_in	IEA	UniProtKB:Q8C0J2\|ensembl:ENSMUSP00000108815	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	sperm midpiece	located_in	ISO	RGD:1553543	1624291	PMID:33087875	RGD	PMID:33087875
Atg16l1	Rat	synapse	is_active_in	IDA		405650312	PMID:28231469	SynGO
Atg16l1	Rat	vacuole-isolation membrane contact site	located_in	ISO	RGD:1321647	1624291	PMID:28890335	RGD	PMID:28890335
Atg16l1	Rat	vacuole-isolation membrane contact site	located_in	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	GTPase binding	enables	ISO	RGD:1321647	1624291	UniProtKB:A1A4Y4 PMID:25891078	RGD	PMID:25891078
Atg16l1	Rat	GTPase binding	enables	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	identical protein binding	enables	ISO	RGD:1321647	1624291	UniProtKB:Q676U5 PMID:20562859, PMID:23392225	RGD	PMID:20562859\|PMID:23392225
Atg16l1	Rat	identical protein binding	enables	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	identical protein binding	enables	ISO	RGD:1553543,PR:Q8C0J2-2	1624291	UniProtKB:Q8C0J2-2 PMID:12665549	RGD	PMID:12665549
Atg16l1	Rat	membrane-membrane adaptor activity	enables	IBA	PANTHER:PTN000459085\|UniProtKB:Q676U5	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Atg16l1	Rat	membrane-membrane adaptor activity	enables	IEA	UniProtKB:Q676U5\|ensembl:ENSP00000375872	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Atg16l1	Rat	membrane-membrane adaptor activity	enables	ISO	RGD:1321647	1624291	PMID:30778222	RGD	PMID:30778222
Atg16l1	Rat	protein binding	enables	ISO	PR:Q8C0J2-3\|RGD:1553543	1624291	UniProtKB:Q9ESK9 PMID:23262492	RGD	PMID:23262492
Atg16l1	Rat	protein binding	enables	ISO	RGD:1553543	1624291	PR:Q80W47\|PR:Q8C0J2\|PR:Q99J83\|PR:Q9ESK9\|UniProtKB:O35963\|UniProtKB:P23242\|UniProtKB:Q61025\|UniProtKB:Q8BHB0\|UniProtKB:Q8C624\|UniProtKB:Q8K3Z0\|UniProtKB:Q99J83\|UniProtKB:Q9ESK9 PMID:12665549, PMID:18448665, PMID:19898471, PMID:19966812, PMID:23392225, PMID:24089209, PMID:24705551, PMID:24954904, PMID:33087875	RGD	PMID:12665549\|PMID:18448665\|PMID:19898471\|PMID:19966812\|PMID:23392225\|PMID:24089209\|PMID:24705551\|PMID:24954904\|PMID:33087875
Atg16l1	Rat	protein binding	enables	ISO	RGD:1553543,PR:Q8C0J2-3	1624291	UniProtKB:Q8TDY2\|UniProtKB:Q9H1Y0 PMID:23262492	RGD	PMID:23262492
Atg16l1	Rat	protein binding	enables	ISO	RGD:1321647,UniProtKB:Q676U5-1	1624291	UniProtKB:P21580\|UniProtKB:Q9BYX4\|UniProtKB:Q9NX02 PMID:31015422	RGD	PMID:31015422
Atg16l1	Rat	protein binding	enables	ISO	RGD:1321647	1624291	UniProtKB:O15553\|UniProtKB:O60603\|UniProtKB:O94817\|UniProtKB:P60520\|UniProtKB:Q14088\|UniProtKB:Q5MNZ9\|UniProtKB:Q8C624\|UniProtKB:Q8TDY2\|UniProtKB:Q9BXS4\|UniProtKB:Q9BXW4\|UniProtKB:Q9GZQ8\|UniProtKB:Q9H082\|UniProtKB:Q9H1Y0\|UniProtKB:Q9HC29\|UniProtKB:Q9NT62\|UniProtKB:Q9Y4P8 PMID:20562859, PMID:23202584, PMID:23262492, PMID:23376921, PMID:23392225, PMID:24191030, PMID:26347139, PMID:28561066, PMID:28890335, PMID:32296183, PMID:32960676, PMID:33087875, PMID:33961781	RGD	PMID:20562859\|PMID:23202584\|PMID:23262492\|PMID:23376921\|PMID:23392225\|PMID:24191030\|PMID:26347139\|PMID:28561066\|PMID:28890335\|PMID:32296183\|PMID:32960676\|PMID:33087875\|PMID:33961781

Molecular Pathway Annotations Click to see Annotation Detail View

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Atg16l1	Rat	autophagy pathway		ISO	RGD:1321647	1643329		RGD
Atg16l1	Rat	autophagy pathway		ISO	RGD:1321647	4889529		RGD

Disease Annotations Click to see Annotation Detail View

Cardiomegaly (IEP)

Crohn's disease (ISO)

inflammatory bowel disease (ISO)

inflammatory bowel disease 10 (ISO,ISS)

Joubert syndrome 22 (ISO)

Liver Reperfusion Injury (ISO)

Perlman syndrome (ISO)

Zika fever (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-chloropropane-1,2-diol (EXP)

4,4'-sulfonyldiphenol (ISO)

acrolein (ISO)

aflatoxin B1 (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

atrazine (ISO)

bis(2-ethylhexyl) phthalate (EXP,ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

C60 fullerene (EXP)

cadmium dichloride (EXP,ISO)

capsaicin (EXP)

copper(II) sulfate (ISO)

coumarin (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenthion (ISO)

folic acid (ISO)

FR900359 (ISO)

fulvestrant (ISO)

galangin (ISO)

gentamycin (EXP)

lycopene (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

melphalan (ISO)

methamphetamine (EXP)

methotrexate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-acetyl-L-cysteine (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pyrroloquinoline quinone (ISO)

rac-lactic acid (ISO)

rotenone (ISO)

sodium arsenite (ISO)

Soman (EXP)

thioacetamide (EXP)

thiram (ISO)

trichloroethene (EXP)

triptonide (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

autophagosome assembly (IBA,IEA,ISO)

axonal transport (IEA,ISO)

C-terminal protein lipidation (ISO)

corpus callosum development (IEA,ISO)

defense response to virus (IEA,ISO)

dendrite arborization (IMP)

hippocampus development (IEA,ISO)

macroautophagy (IEA,ISO)

microautophagy (IEA,ISO)

negative regulation of dendrite extension (IMP)

negative stranded viral RNA replication (IEA,ISO)

positive regulation of autophagy (IEA,ISO)

protein lipidation involved in autophagosome assembly (ISO)

protein localization to phagophore assembly site (IEA,ISO)

xenophagy (IEA,ISO)

Cellular Component

Atg12-Atg5-Atg16 complex (IBA,IEA,ISO)

autophagosome (IEA,ISO)

autophagosome membrane (IBA,IEA,ISO)

axon (IEA)

axoneme (IEA,ISO)

cytoplasm (IEA,ISO)

endolysosome membrane (IEA,ISO)

glutamatergic synapse (IDA,IEA,ISO)

phagophore assembly site membrane (IBA,IEA,ISO)

sperm midpiece (IEA,ISO)

synapse (IDA)

vacuole-isolation membrane contact site (IEA,ISO)

Molecular Function

GTPase binding (IEA,ISO)

identical protein binding (IEA,ISO)

membrane-membrane adaptor activity (IBA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

autophagy pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Melatonin protects against developmental PBDE-47 neurotoxicity by targeting the AMPK/mitophagy axis.	Dong L, etal., J Pineal Res. 2023 Aug;75(1):e12871. doi: 10.1111/jpi.12871. Epub 2023 Apr 27.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	δ-Catenin engages the autophagy pathway to sculpt the developing dendritic arbor.	Ligon C, etal., J Biol Chem. 2020 Aug 7;295(32):10988-11001. doi: 10.1074/jbc.RA120.013058. Epub 2020 Jun 17.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Bassoon Controls Presynaptic Autophagy through Atg5.	Okerlund ND, etal., Neuron. 2017 Feb 22;93(4):897-913.e7. doi: 10.1016/j.neuron.2017.01.026.
6.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation
10.	Hepatic interferon regulatory factor 8 expression mediates liver ischemia/reperfusion injury in mice.	Shi G, etal., Biochem Pharmacol. 2021 Oct;192:114728. doi: 10.1016/j.bcp.2021.114728. Epub 2021 Aug 13.
11.	LC3 conjugation system in mammalian autophagy.	Tanida I, etal., Int J Biochem Cell Biol. 2004 Dec;36(12):2503-18.
12.	Aliskiren ameliorates pressure overload-induced heart hypertrophy and fibrosis in mice.	Weng LQ, etal., Acta Pharmacol Sin. 2014 Aug;35(8):1005-14. doi: 10.1038/aps.2014.45. Epub 2014 Jul 7.
13.	Mammalian autophagy: core molecular machinery and signaling regulation.	Yang Z and Klionsky DJ, Curr Opin Cell Biol. 2010 Apr;22(2):124-31. Epub 2009 Dec 23.

Additional References at PubMed

PMID:8889548	PMID:12665549	PMID:20562859	PMID:21220506	PMID:22740627	PMID:23392225	PMID:24089209	PMID:24550300	PMID:24954904	PMID:25891078	PMID:26845845	PMID:28860495
PMID:29634390	PMID:30208760	PMID:33818130	PMID:33843019	PMID:35503135

Genomics

Comparative Map Data

Atg16l1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	95,869,839 - 95,905,354 (+)	NCBI		GRCr8
mRatBN7.2	9	88,420,737 - 88,457,530 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	88,422,038 - 88,457,529 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	96,846,724 - 96,882,032 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	101,982,902 - 102,018,214 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	100,350,405 - 100,385,741 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	94,879,876 - 94,915,231 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	94,879,745 - 94,915,228 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	94,599,174 - 94,634,551 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	86,712,122 - 86,747,370 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	86,895,541 - 86,929,665 (+)	NCBI
Celera	9	85,830,765 - 85,865,957 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

ATG16L1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	233,251,673 - 233,295,669 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	233,210,051 - 233,295,674 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	234,160,319 - 234,204,315 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	233,824,956 - 233,869,059 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	227,881,745 - 227,925,836 (+)	NCBI		Celera
Cytogenetic Map	2	q37.1	NCBI
HuRef	2	225,960,992 - 226,005,094 (+)	NCBI		HuRef
CHM1_1	2	234,166,299 - 234,210,402 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	2	233,739,756 - 233,783,753 (+)	NCBI		T2T-CHM13v2.0

Atg16l1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	87,683,730 - 87,720,150 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	87,683,592 - 87,720,150 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	87,756,007 - 87,792,428 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	87,755,870 - 87,792,428 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	89,652,646 - 89,688,997 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	89,587,242 - 89,623,593 (+)	NCBI		MGSCv36	mm8
Celera	1	90,714,013 - 90,750,352 (+)	NCBI		Celera
Cytogenetic Map	1	D	NCBI
cM Map	1	44.44	NCBI

Atg16l1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955453	2,880,928 - 2,917,581 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955453	2,884,497 - 2,917,581 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATG16L1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	13	135,853,482 - 135,897,461 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2B	135,868,447 - 135,912,425 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2B	120,479,534 - 120,523,563 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2B	239,392,990 - 239,436,766 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	239,392,990 - 239,436,766 (+)	Ensembl	panpan1.1		panPan2

ATG16L1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	44,761,034 - 44,800,033 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	44,761,185 - 44,798,672 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	45,256,465 - 45,295,672 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	45,020,993 - 45,060,197 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	45,020,983 - 45,060,197 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	44,945,410 - 44,984,592 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	44,791,409 - 44,830,551 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	44,946,602 - 44,985,778 (+)	NCBI		UU_Cfam_GSD_1.0

Atg16l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	186,929,271 - 186,966,233 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936525	3,972,558 - 4,010,514 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936525	3,973,574 - 4,010,442 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATG16L1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	133,651,298 - 133,693,468 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	133,651,294 - 133,693,472 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	147,677,835 - 147,718,756 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATG16L1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	119,286,609 - 119,331,226 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	119,286,751 - 119,333,267 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	80,173,329 - 80,218,029 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atg16l1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624843	5,805,069 - 5,838,741 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624843	5,797,725 - 5,838,768 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Atg16l1
165 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	464
Count of miRNA genes:	239
Interacting mature miRNAs:	299
Transcripts:	ENSRNOT00000024445
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631656	Bp108	Blood pressure QTL 108	5.97	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	48598251	93598251	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
724515	Uae16	Urinary albumin excretion QTL 16	8		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	58163035	100929646	Rat
731171	Glom6	Glomerulus QTL 6	2.8	0.0003	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	9	64573531	109573531	Rat
724547	Cm21	Cardiac mass QTL 21	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	9	79271511	102910209	Rat
61385	Edpm9	Estrogen-dependent pituitary mass QTL 9	3.43	0.05	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	9	63869687	108869687	Rat
2303178	Bp334	Blood pressure QTL 334	3.7	0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	79271511	91616855	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
1578760	Cm53	Cardiac mass QTL 53	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	56771635	101771635	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
1581580	Uae34	Urinary albumin excretion QTL 34			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	62072275	96470995	Rat
1300134	Bp185	Blood pressure QTL 185	3.73		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	9	61381434	104821652	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
1354626	Bvd1	Brain ventricular dilatation QTL 1	3.73	0.001	brain ventricle morphology trait (VT:0000822)	hydrocephalus severity score (CMO:0001881)	9	75712843	111552878	Rat
4889852	Pur26	Proteinuria QTL 26	15	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	77813894	101597663	Rat
7794784	Mcs31	Mammary carcinoma susceptibility QTL 31	2.98		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	9	77813894	111552878	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1578757	Pur6	Proteinuria QTL 6	3.3	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	62072275	96470995	Rat
4889943	Bss90	Bone structure and strength QTL 90	4.1		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	9	86369631	92058970	Rat

Markers in Region

BE120484

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,450,809 - 88,450,973 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	94,908,513 - 94,908,676	NCBI	Rnor6.0
Rnor_5.0	9	94,627,833 - 94,627,996	UniSTS	Rnor5.0
RGSC_v3.4	9	86,740,651 - 86,740,814	UniSTS	RGSC3.4
Celera	9	85,859,238 - 85,859,401	UniSTS
Cytogenetic Map	9	q35	UniSTS

RH137932

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,449,736 - 88,449,911 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	94,907,440 - 94,907,614	NCBI	Rnor6.0
Rnor_5.0	9	94,626,760 - 94,626,934	UniSTS	Rnor5.0
RGSC_v3.4	9	86,739,578 - 86,739,752	UniSTS	RGSC3.4
Celera	9	85,858,165 - 85,858,339	UniSTS
Cytogenetic Map	9	q35	UniSTS

RH139068

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	88,453,825 - 88,453,993 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	94,911,525 - 94,911,692	NCBI	Rnor6.0
Rnor_5.0	9	94,630,845 - 94,631,012	UniSTS	Rnor5.0
RGSC_v3.4	9	86,743,667 - 86,743,834	UniSTS	RGSC3.4
Celera	9	85,862,254 - 85,862,421	UniSTS
Cytogenetic Map	9	q35	UniSTS

Genetic Models

This gene Atg16l1 is modified in the following models/strains:

F344-Atg16l1^em8Rrrc

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245419	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006245420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039083917	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267451	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063267452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA925215	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB605957	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB782885	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK473997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK481169	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CO393878	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EV774911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000024445 ⟹ ENSRNOP00000024445

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	88,422,038 - 88,457,529 (+)	Ensembl
Rnor_6.0 Ensembl	9	94,880,053 - 94,915,228 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000080482 ⟹ ENSRNOP00000075135

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	88,422,038 - 88,457,529 (+)	Ensembl
Rnor_6.0 Ensembl	9	94,879,745 - 94,915,204 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000114063 ⟹ ENSRNOP00000097226

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	88,422,038 - 88,457,529 (+)	Ensembl

RefSeq Acc Id:

NM_001108809 ⟹ NP_001102279

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,870,013 - 95,905,354 (+)	NCBI
mRatBN7.2	9	88,422,181 - 88,457,529 (+)	NCBI
Rnor_6.0	9	94,880,053 - 94,915,228 (+)	NCBI
Rnor_5.0	9	94,599,174 - 94,634,551 (+)	NCBI
RGSC_v3.4	9	86,712,122 - 86,747,370 (+)	RGD
Celera	9	85,830,765 - 85,865,957 (+)	RGD

Sequence:

show sequence

CATGTCGTCGGGCCTCCGCGCCGCAGACTTTCCCCGCTGGAAGCGCCACATCGCGGAGGAACTG
AGGCGCCGGGACCGGCTGCAGAGGCAGGCGTTCGAGGAGATCATTCTGCAGTATACCAAGTTGC
TGGAGAAGTCAGATCTTCATTCAGTATTGACCCAGAAACTACAGGCTGAAAAGCACGACGTACC
AAATAGGCATGAAATAAGTCCTGGGCACGATGGTGCATGGAATGACAGTCAGCTACAAGAAATG
GCCCAGTTGAAGATGAAACACCAGGAAGAGCTGACTGAACTGCACAAGAAGCGTGGGGAGTTAG
CTCAGTTGGTGATTGACCTGAATAACCAGATGCAGCAGAAGGACAAGGAGATACAGACGAATGA
AGCAAAGATTGCAGAGTGTTTACAGACCATCTCTGACCTGGAGGCAGACTGCCTGGACCTGCGC
ACCAAACTGCAGGACCTTGAGGTAGCCAACCAGACCCTGAAGGATGAGTATGATGCCCTGCAGA
TTACTTTTACTGCCCTAGAAGAGAAACTGAGGAAAACTACTGAGGAGAACCAGGAACTGGTCAC
CAGGTGGATGGCTGAGAAGGCCCAAGAAGCCAATCGCCTTAATGCGGAGAATGAGAAGGACTCC
AGGAGGCGACAAGCACGGTTGCAGAAGGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCTGTCG
AACAGGATGATGACATTGAAGTCATTGTAGATGAGACCTCAGATCACACAGAAGAGACCTCTCC
TGTGCGAGCCATCAGCAGAGCAGCTACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGAT
TCTATCACTAATATCTTTGGGAGACGCTCTGTCTCTTCCATCCCAGTCCCCCAAGATGTCGTGG
ACACTCATCCTGCTTCTGGTAAAGATGTGAGAGTCCCAACTACTGCCTCGTATGTCTTTGATGC
ACATGACGGAGAGGTCAATGCAGTACAGTTCAGTCCAGGCTCCCGGTTACTGGCCACTGGAGGC
ATGGACCGCAGGGTTAAACTTTGGGAAGCATTCGGAGATAAATGTGAATTCAAGGGCTCCCTGT
CTGGCAGCAATGCGGGAATTACAAGCATTGAATTTGATAGTGCTGGAGCTTACCTATTAGCAGC
TTCAAATGATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTTACC
GGCCACAGCGGGAAAGTTCTCTCTGCCAAGTTCCTGCTGGACAATGCACGGATAGTCTCAGGAA
GTCATGACCGGACCCTCAAACTCTGGGATCTCCGCAGCAAAGTCTGTATCAAAACAGTGTTCGC
AGGGTCCAGCTGCAATGACATTGTTTGCACTGAGCAATGTGTAATGAGTGGACATTTTGACAAG
AAAATTCGTTTCTGGGATATCCGGTCAGAGAGTGTGGTCCGAGAGATGGAACTGTTAGGGAAGA
TCACTGCTCTGGACTTAAACCCCGAGAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACCTGCT
AAAAATCATTGACCTGCGGACAAACGCCATCAAGCAGTCATTCAGTGCACCTGGATTCAAGTGT
GGCTCTGACTGGACCCGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCAGCAGGCTCAGCTG
ACGGCTCTCTTTATGTATGGAGTGTGCTCACGGGGAAAGTAGAGAAGGTTCTCTCCAAGCAGCA
CAGCTCTTCTATCAATGCGGTGGCGTGGGCCCCCTCTGGCTTACATGTTGTCAGTGTGGACAAA
GGAAGCAGAGCTGTGCTATGGGCACAGCCTTGATGCCACTCCCTGAGGAGCAGCGTGGGACCCC
GCAGCCCATTTTGGAGAATGATGTGTCCTCCCAGAGAAGAGCTGAAGCTATATGGCACCCACCG
TACCTTTCCTAAGAACTTTGACTTAAGGTCTCTAATGGGTGAGAAGAACCAACACAGAACCAAA
CTGACTCGCACGTCCCTAGCAGGGGTTCCGGTTCTTGTCGCATGTGGGTGGGAAACACTACTAA
CTCTGACCTTCCATACCTCATGGGGAGCACAGGGTCCCTGCTGGGTCTCCCCACTGGACACAGT
GCCAAGGACAGCCCCACACATCGGGTATTGGGTCCCCTGTGCTTTTCCCGTCTTTCCAAAGTCT
GTTGTAGCCTGATGCACACCCCTTTTCTGTGGGGTCACTTACCCAGGGGGCTCACTGAAGGCAT
TGGGTTAGTGGAAACCAAATCAGGGCCTGTCCTCCTGTGACAAAGGATGGGTGGGGCTGTTTTC
AGGGCTGGTGATATGTCTGGTCTCACTGCTGAAACCTGCATCTTGAGCTGGCCTTCAGAACTCC
GAGCTCCCTTCCTGCCAACACCTACACATAGCTTTGTGTGTGCGAGGAAAGAACTGTGCCAACC
TTTCCCTGTCCGGTAGAATTTGCCGCTGAAATGAGAAACACATCTTTACCCAGCATCACTGCCA
GTCACAGCAGTGGCTTAGCGCTCATCTGGAGCTGGTGGTGGGGAGTCCAGCCACTGCCTGTGTA
TGCAGTGTAGTGTTGGTAAGAGAAGCCTATCTGGGAGCTGGTCATGCTGAAGGCTGGGAAAGCA
CCCTCTGTCCTGCTTACCCATGCACACGGTCTGAGCACGGTGTCTGGGTGTCCAAAGCACCACG
TTTGTCACATTTACTTTGCACTTTATTTTTTGCTTCCGCGCTGGCTCTCTGGACAGTAGGAACA
GACATGAGTTCTAGAACTAGGGAAGAGGGACAGCAGTCCTTCCCTGCTTGCAACTCACCTGTCA
TTCGCTGCCAGAGAGCTAGTGGTGTTGGGAGTTGAGAGTGGCTGGCCAGGGCACATCTTTTATT
TATTTAATTATGTGTCCCAACAGAACTTGACTGTAAATAAAGAAGAAATTCTGTTATATACTTT
TCAAA

hide sequence

RefSeq Acc Id:

XM_006245419 ⟹ XP_006245481

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,869,839 - 95,905,354 (+)	NCBI
mRatBN7.2	9	88,421,916 - 88,457,530 (+)	NCBI
Rnor_6.0	9	94,879,876 - 94,915,231 (+)	NCBI
Rnor_5.0	9	94,599,174 - 94,634,551 (+)	NCBI

Sequence:

show sequence

ACATAATTTCCGGCAGACACCGGAAAACCATCCCAGATAGCCTCAGGGGTGCCCGGTGTGGAGA
GGTGAGGTTCCGGAGGCCGGCTTCTGTTGGCTCGCGCCTTGCAGCACGCTGCAACCTGCAGTCC
TGAGTGTCGGCGCGGATCGGCCGCCCTGAGGCGCCGGGGCAGCATTCGACATGTCGTCGGGCCT
CCGCGCCGCAGACTTTCCCCGCTGGAAGCGCCACATCGCGGAGGAACTGAGGCGCCGGGACCGG
CTGCAGAGGCAGGCGTTCGAGGAGATCATTCTGCAGTATACCAAGTTGCTGGAGAAGTCAGATC
TTCATTCAGTATTGACCCAGAAACTACAGGCTGAAAAGCACGACGTACCAAATAGGCATGAAAT
AAGTCCTGGGCACGATGGTGCATGGAATGACAGTCAGCTACAAGAAATGGCCCAGTTGAAGATG
AAACACCAGGAAGAGCTGACTGAACTGCACAAGAAGCGTGGGGAGTTAGCTCAGTTGGTGATTG
ACCTGAATAACCAGATGCAGCAGAAGGACAAGGAGATACAGACGAATGAAGCAAAGATTGCAGA
GTGTTTACAGACCATCTCTGACCTGGAGGCAGACTGCCTGGACCTGCGCACCAAACTGCAGGAC
CTTGAGGTAGCCAACCAGACCCTGAAGGATGAGTATGATGCCCTGCAGATTACTTTTACTGCCC
TAGAAGAGAAACTGAGGAAAACTACTGAGGAGAACCAGGAACTGGTCACCAGGTGGATGGCTGA
GAAGGCCCAAGAAGCCAATCGCCTTAATGCGGAGAATGAGAAGGACTCCAGGAGGCGACAAGCA
CGGTTGCAGAAGGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCTGTCGAACAGGATGATGACA
TTGAAGTCATTGTAGATGAGACCTCAGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAG
CAGAGCAGCTACTAAGCGACTCTCGCAGCCTGCTGGAGGCCTTCTGGATTCTATCACTAATATC
TTTGGTCTGTCCGAATCTCCCCTTTTGGGACATCATTCTTCTGATGCTGCCAGGAGACGCTCTG
TCTCTTCCATCCCAGTCCCCCAAGATGTCGTGGACACTCATCCTGCTTCTGGTAAAGATGTGAG
AGTCCCAACTACTGCCTCGTATGTCTTTGATGCACATGACGGAGAGGTCAATGCAGTACAGTTC
AGTCCAGGCTCCCGGTTACTGGCCACTGGAGGCATGGACCGCAGGGTTAAACTTTGGGAAGCAT
TCGGAGATAAATGTGAATTCAAGGGCTCCCTGTCTGGCAGCAATGCGGGAATTACAAGCATTGA
ATTTGATAGTGCTGGAGCTTACCTATTAGCAGCTTCAAATGATTTTGCAAGCCGAATCTGGACT
GTGGATGATTATCGATTACGGCACACACTTACCGGCCACAGCGGGAAAGTTCTCTCTGCCAAGT
TCCTGCTGGACAATGCACGGATAGTCTCAGGAAGTCATGACCGGACCCTCAAACTCTGGGATCT
CCGCAGCAAAGTCTGTATCAAAACAGTGTTCGCAGGGTCCAGCTGCAATGACATTGTTTGCACT
GAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCGTTTCTGGGATATCCGGTCAGAGA
GTGTGGTCCGAGAGATGGAACTGTTAGGGAAGATCACTGCTCTGGACTTAAACCCCGAGAGGAC
TGAGCTCCTGAGCTGCTCCCGTGATGACCTGCTAAAAATCATTGACCTGCGGACAAACGCCATC
AAGCAGTCATTCAGTGCACCTGGATTCAAGTGTGGCTCTGACTGGACCCGAGTTGTCTTCAGCC
CTGATGGCAGTTACGTGGCAGCAGGCTCAGCTGACGGCTCTCTTTATGTATGGAGTGTGCTCAC
GGGGAAAGTAGAGAAGGTTCTCTCCAAGCAGCACAGCTCTTCTATCAATGCGGTGGCGTGGGCC
CCCTCTGGCTTACATGTTGTCAGTGTGGACAAAGGAAGCAGAGCTGTGCTATGGGCACAGCCTT
GATGCCACTCCCTGAGGAGCAGCGTGGGACCCCGCAGCCCATTTTGGAGAATGATGTGTCCTCC
CAGAGAAGAGCTGAAGCTATATGGCACCCACCGTACCTTTCCTAAGAACTTTGACTTAAGGTCT
CTAATGGGTGAGAAGAACCAACACAGAACCAAACTGACTCGCACGTCCCTAGCAGGGGTTCCGG
TTCTTGTCGCATGTGGGTGGGAAACACTACTAACTCTGACCTTCCATACCTCATGGGGAGCACA
GGGTCCCTGCTGGGTCTCCCCACTGGACACAGTGCCAAGGACAGCCCCACACATCGGGTATTGG
GTCCCCTGTGCTTTTCCCGTCTTTCCAAAGTCTGTTGTAGCCTGATGCACACCCCTTTTCTGTG
GGGTCACTTACCCAGGGGGCTCACTGAAGGCATTGGGTTAGTGGAAACCAAATCAGGGCCTGTC
CTCCTGTGACAAAGGATGGGTGGGGCTGTTTTCAGGGCTGGTGATATGTCTGGTCTCACTGCTG
AAACCTGCATCTTGAGCTGGCCTTCAGAACTCCGAGCTCCCTTCCTGCCAACACCTACACATAG
CTTTGTGTGTGCGAGGAAAGAACTGTGCCAACCTTTCCCTGTCCGGTAGAATTTGCCGCTGAAA
TGAGAAACACATCTTTACCCAGCATCACTGCCAGTCACAGCAGTGGCTTAGCGCTCATCTGGAG
CTGGTGGTGGGGAGTCCAGCCACTGCCTGTGTATGCAGTGTAGTGTTGGTAAGAGAAGCCTATC
TGGGAGCTGGTCATGCTGAAGGCTGGGAAAGCACCCTCTGTCCTGCTTACCCATGCACACGGTC
TGAGCACGGTGTCTGGGTGTCCAAAGCACCACGTTTGTCACATTTACTTTGCACTTTATTTTTT
GCTTCCGCGCTGGCTCTCTGGACAGTAGGAACAGACATGAGTTCTAGAACTAGGGAAGAGGGAC
AGCAGTCCTTCCCTGCTTGCAACTCACCTGTCATTCGCTGCCAGAGAGCTAGTGGTGTTGGGAG
TTGAGAGTGGCTGGCCAGGGCACATCTTTTATTTATTTAATTATGTGTCCCAACAGAACTTGAC
TGTAAATAAAGAAGAAATTCTGTTATATACTTTTCAAACTC

hide sequence

RefSeq Acc Id:

XM_006245420 ⟹ XP_006245482

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,869,840 - 95,905,354 (+)	NCBI
mRatBN7.2	9	88,421,942 - 88,457,530 (+)	NCBI
Rnor_6.0	9	94,879,876 - 94,915,231 (+)	NCBI
Rnor_5.0	9	94,599,174 - 94,634,551 (+)	NCBI

Sequence:

show sequence

ACATAATTTCCGGCAGACACCGGAAAACCATCCCAGATAGCCTCAGGGGTGCCCGGTGTGGAGA
GGTGAGGTTCCGGAGGCCGGCTTCTGTTGGCTCGCGCCTTGCAGCACGCTGCAACCTGCAGTCC
TGAGTGTCGGCGCGGATCGGCCGCCCTGAGGCGCCGGGGCAGCATTCGACATGTCGTCGGGCCT
CCGCGCCGCAGACTTTCCCCGCTGGAAGCGCCACATCGCGGAGGAACTGAGGCGCCGGGACCGG
CTGCAGAGGCAGGCGTTCGAGGAGATCATTCTGCAGTATACCAAGTTGCTGGAGAAGTCAGATC
TTCATTCAGTATTGACCCAGAAACTACAGGCTGAAAAGCACGACGTACCAAATAGGCATGAAAT
AAGTCCTGGGCACGATGGTGCATGGAATGACAGTCAGCTACAAGAAATGGCCCAGTTGAAGATG
AAACACCAGGAAGAGCTGACTGAACTGCACAAGAAGCGTGGGGAGTTAGCTCAGTTGGTGATTG
ACCTGAATAACCAGATGCAGCAGAAGGACAAGGAGATACAGACGAATGAAGCAAAGATTGCAGA
GTGTTTACAGACCATCTCTGACCTGGAGGCAGACTGCCTGGACCTGCGCACCAAACTGCAGGAC
CTTGAGGTAGCCAACCAGACCCTGAAGGATGAGTATGATGCCCTGCAGATTACTTTTACTGCCC
TAGAAGAGAAACTGAGGAAAACTACTGAGGAGAACCAGGAACTGGTCACCAGGTGGATGGCTGA
GAAGGCCCAAGAAGCCAATCGCCTTAATGCGGAGAATGAGAAGGACTCCAGGAGGCGACAAGCA
CGGTTGCAGAAGGAGCTTGCAGAAGCAGCAAAGGAACCTCTACCTGTCGAACAGGATGATGACA
TTGAAGTCATTGTAGATGAGACCTCAGATCACACAGAAGAGACCTCTCCTGTGCGAGCCATCAG
CAGAGCAGCTACGAGACGCTCTGTCTCTTCCATCCCAGTCCCCCAAGATGTCGTGGACACTCAT
CCTGCTTCTGGTAAAGATGTGAGAGTCCCAACTACTGCCTCGTATGTCTTTGATGCACATGACG
GAGAGGTCAATGCAGTACAGTTCAGTCCAGGCTCCCGGTTACTGGCCACTGGAGGCATGGACCG
CAGGGTTAAACTTTGGGAAGCATTCGGAGATAAATGTGAATTCAAGGGCTCCCTGTCTGGCAGC
AATGCGGGAATTACAAGCATTGAATTTGATAGTGCTGGAGCTTACCTATTAGCAGCTTCAAATG
ATTTTGCAAGCCGAATCTGGACTGTGGATGATTATCGATTACGGCACACACTTACCGGCCACAG
CGGGAAAGTTCTCTCTGCCAAGTTCCTGCTGGACAATGCACGGATAGTCTCAGGAAGTCATGAC
CGGACCCTCAAACTCTGGGATCTCCGCAGCAAAGTCTGTATCAAAACAGTGTTCGCAGGGTCCA
GCTGCAATGACATTGTTTGCACTGAGCAATGTGTAATGAGTGGACATTTTGACAAGAAAATTCG
TTTCTGGGATATCCGGTCAGAGAGTGTGGTCCGAGAGATGGAACTGTTAGGGAAGATCACTGCT
CTGGACTTAAACCCCGAGAGGACTGAGCTCCTGAGCTGCTCCCGTGATGACCTGCTAAAAATCA
TTGACCTGCGGACAAACGCCATCAAGCAGTCATTCAGTGCACCTGGATTCAAGTGTGGCTCTGA
CTGGACCCGAGTTGTCTTCAGCCCTGATGGCAGTTACGTGGCAGCAGGCTCAGCTGACGGCTCT
CTTTATGTATGGAGTGTGCTCACGGGGAAAGTAGAGAAGGTTCTCTCCAAGCAGCACAGCTCTT
CTATCAATGCGGTGGCGTGGGCCCCCTCTGGCTTACATGTTGTCAGTGTGGACAAAGGAAGCAG
AGCTGTGCTATGGGCACAGCCTTGATGCCACTCCCTGAGGAGCAGCGTGGGACCCCGCAGCCCA
TTTTGGAGAATGATGTGTCCTCCCAGAGAAGAGCTGAAGCTATATGGCACCCACCGTACCTTTC
CTAAGAACTTTGACTTAAGGTCTCTAATGGGTGAGAAGAACCAACACAGAACCAAACTGACTCG
CACGTCCCTAGCAGGGGTTCCGGTTCTTGTCGCATGTGGGTGGGAAACACTACTAACTCTGACC
TTCCATACCTCATGGGGAGCACAGGGTCCCTGCTGGGTCTCCCCACTGGACACAGTGCCAAGGA
CAGCCCCACACATCGGGTATTGGGTCCCCTGTGCTTTTCCCGTCTTTCCAAAGTCTGTTGTAGC
CTGATGCACACCCCTTTTCTGTGGGGTCACTTACCCAGGGGGCTCACTGAAGGCATTGGGTTAG
TGGAAACCAAATCAGGGCCTGTCCTCCTGTGACAAAGGATGGGTGGGGCTGTTTTCAGGGCTGG
TGATATGTCTGGTCTCACTGCTGAAACCTGCATCTTGAGCTGGCCTTCAGAACTCCGAGCTCCC
TTCCTGCCAACACCTACACATAGCTTTGTGTGTGCGAGGAAAGAACTGTGCCAACCTTTCCCTG
TCCGGTAGAATTTGCCGCTGAAATGAGAAACACATCTTTACCCAGCATCACTGCCAGTCACAGC
AGTGGCTTAGCGCTCATCTGGAGCTGGTGGTGGGGAGTCCAGCCACTGCCTGTGTATGCAGTGT
AGTGTTGGTAAGAGAAGCCTATCTGGGAGCTGGTCATGCTGAAGGCTGGGAAAGCACCCTCTGT
CCTGCTTACCCATGCACACGGTCTGAGCACGGTGTCTGGGTGTCCAAAGCACCACGTTTGTCAC
ATTTACTTTGCACTTTATTTTTTGCTTCCGCGCTGGCTCTCTGGACAGTAGGAACAGACATGAG
TTCTAGAACTAGGGAAGAGGGACAGCAGTCCTTCCCTGCTTGCAACTCACCTGTCATTCGCTGC
CAGAGAGCTAGTGGTGTTGGGAGTTGAGAGTGGCTGGCCAGGGCACATCTTTTATTTATTTAAT
TATGTGTCCCAACAGAACTTGACTGTAAATAAAGAAGAAATTCTGTTATATACTTTTCAAACTC

hide sequence

RefSeq Acc Id:

XM_039083917 ⟹ XP_038939845

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,869,839 - 95,905,354 (+)	NCBI
mRatBN7.2	9	88,420,737 - 88,457,530 (+)	NCBI

RefSeq Acc Id:

XM_063267450 ⟹ XP_063123520

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,869,839 - 95,905,354 (+)	NCBI

RefSeq Acc Id:

XM_063267451 ⟹ XP_063123521

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,884,824 - 95,905,354 (+)	NCBI

RefSeq Acc Id:

XM_063267452 ⟹ XP_063123522

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	95,884,824 - 95,905,354 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001102279	(Get FASTA)	NCBI Sequence Viewer
	XP_006245481	(Get FASTA)	NCBI Sequence Viewer
	XP_006245482	(Get FASTA)	NCBI Sequence Viewer
	XP_038939845	(Get FASTA)	NCBI Sequence Viewer
	XP_063123520	(Get FASTA)	NCBI Sequence Viewer
	XP_063123521	(Get FASTA)	NCBI Sequence Viewer
	XP_063123522	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL75656	(Get FASTA)	NCBI Sequence Viewer
	EDL75657	(Get FASTA)	NCBI Sequence Viewer
	EDL75658	(Get FASTA)	NCBI Sequence Viewer
	EDL75659	(Get FASTA)	NCBI Sequence Viewer
	EDL75660	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000024445
	ENSRNOP00000024445.3
	ENSRNOP00000075135
	ENSRNOP00000075135.1
	ENSRNOP00000097226
	ENSRNOP00000097226.1

RefSeq Acc Id:

NP_001102279 ⟸ NM_001108809

- UniProtKB:

D3ZFK6 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDVP
NRHEISPGHDGAWNDSQLQEMAQLKMKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQTNE
AKIAECLQTISDLEADCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVT
RWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSP
VRAISRAATKRLSQPAGGLLDSITNIFGRRSVSSIPVPQDVVDTHPASGKDVRVPTTASYVFDA
HDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAA
SNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFA
GSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLL
KIIDLRTNAIKQSFSAPGFKCGSDWTRVVFSPDGSYVAAGSADGSLYVWSVLTGKVEKVLSKQH
SSSINAVAWAPSGLHVVSVDKGSRAVLWAQP

hide sequence

RefSeq Acc Id:	XP_006245481 ⟸ XM_006245419
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2K9U6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDVP NRHEISPGHDGAWNDSQLQEMAQLKMKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQTNE AKIAECLQTISDLEADCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVT RWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSP VRAISRAATKRLSQPAGGLLDSITNIFGLSESPLLGHHSSDAARRRSVSSIPVPQDVVDTHPAS GKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLATGGMDRRVKLWEAFGDKCEFKGSLSGSNAG ITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHTLTGHSGKVLSAKFLLDNARIVSGSHDRTL KLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHFDKKIRFWDIRSESVVREMELLGKITALDL NPERTELLSCSRDDLLKIIDLRTNAIKQSFSAPGFKCGSDWTRVVFSPDGSYVAAGSADGSLYV WSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSVDKGSRAVLWAQP hide sequence

RefSeq Acc Id:	XP_006245482 ⟸ XM_006245420
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6GLZ1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSSGLRAADFPRWKRHIAEELRRRDRLQRQAFEEIILQYTKLLEKSDLHSVLTQKLQAEKHDVP NRHEISPGHDGAWNDSQLQEMAQLKMKHQEELTELHKKRGELAQLVIDLNNQMQQKDKEIQTNE AKIAECLQTISDLEADCLDLRTKLQDLEVANQTLKDEYDALQITFTALEEKLRKTTEENQELVT RWMAEKAQEANRLNAENEKDSRRRQARLQKELAEAAKEPLPVEQDDDIEVIVDETSDHTEETSP VRAISRAATRRSVSSIPVPQDVVDTHPASGKDVRVPTTASYVFDAHDGEVNAVQFSPGSRLLAT GGMDRRVKLWEAFGDKCEFKGSLSGSNAGITSIEFDSAGAYLLAASNDFASRIWTVDDYRLRHT LTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVCIKTVFAGSSCNDIVCTEQCVMSGHF DKKIRFWDIRSESVVREMELLGKITALDLNPERTELLSCSRDDLLKIIDLRTNAIKQSFSAPGF KCGSDWTRVVFSPDGSYVAAGSADGSLYVWSVLTGKVEKVLSKQHSSSINAVAWAPSGLHVVSV DKGSRAVLWAQP hide sequence

Ensembl Acc Id:

ENSRNOP00000075135 ⟸ ENSRNOT00000080482

Ensembl Acc Id:

ENSRNOP00000024445 ⟸ ENSRNOT00000024445

RefSeq Acc Id:	XP_038939845 ⟸ XM_039083917
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000097226 ⟸ ENSRNOT00000114063

RefSeq Acc Id:	XP_063123520 ⟸ XM_063267450
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063123521 ⟸ XM_063267451
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063123522 ⟸ XM_063267452
- Peptide Label:	isoform X6

Protein Domains

Autophagy-related protein

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A0A0G2K9U6-F1-model_v2	AlphaFold	A0A0G2K9U6	1-623	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696840

Promoter ID:

EPDNEW_R7364

Type:

multiple initiation site

Name:

Atg16l1_1

Description:

autophagy related 16-like 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	94,879,907 - 94,879,967	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310631	AgrOrtholog
BioCyc Gene	G2FUF-26835	BioCyc
Ensembl Genes	ENSRNOG00000017913	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000024445	ENTREZGENE
	ENSRNOT00000024445.4	UniProtKB/TrEMBL
	ENSRNOT00000080482	ENTREZGENE
	ENSRNOT00000080482.2	UniProtKB/TrEMBL
	ENSRNOT00000114063	ENTREZGENE
	ENSRNOT00000114063.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.5.170	UniProtKB/TrEMBL
	2.130.10.10	UniProtKB/TrEMBL
InterPro	ATG16	UniProtKB/TrEMBL
	Autophagy-rel_prot_16	UniProtKB/TrEMBL
	G-protein_beta_WD-40_rep_reg	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:363278	UniProtKB/TrEMBL
NCBI Gene	363278	ENTREZGENE
PANTHER	AUTOPHAGY-RELATED PROTEIN 16-1	UniProtKB/TrEMBL
	PTHR19878	UniProtKB/TrEMBL
Pfam	ATG16	UniProtKB/TrEMBL
	WD40	UniProtKB/TrEMBL
PhenoGen	Atg16l1	PhenoGen
PRINTS	GPROTEINBRPT	UniProtKB/TrEMBL
PROSITE	WD_REPEATS_1	UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000017913	RatGTEx
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	WD40_like	UniProtKB/TrEMBL
UniProt	A0A0G2K9U6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GLZ1	ENTREZGENE, UniProtKB/TrEMBL
	D3ZFK6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-06-24	Atg16l1	autophagy related 16-like 1	Atg16l1	autophagy related 16-like 1 (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-06-07	Atg16l1	autophagy related 16-like 1 (S. cerevisiae)	Atg16l1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Atg16l1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	Atg16l1	autophagy-related 16-like 1 (yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-03	Atg16l1	autophagy-related 16-like 1 (yeast)	Atg16l1_predicted	ATG16 autophagy related 16-like 1 (S. cerevisiae) (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Atg16l1_predicted	ATG16 autophagy related 16-like 1 (S. cerevisiae) (predicted)	Apg16l_predicted	APG16 autophagy 16-like (S. cerevisiae) (predicted)	Symbol and Name updated	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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