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Gene: Ank2 (ankyrin 2) Rattus norvegicus
Symbol: Ank2
Name: ankyrin 2
RGD ID: 620156
Description: Exhibits ion channel binding activity and protein kinase binding activity. Involved in paranodal junction assembly and response to methylmercury. Localizes to several cellular components, including cytoskeleton; membrane raft; and neuron projection. Biomarker of transient cerebral ischemia. Human ortholog(s) of this gene implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome. Orthologous to human ANK2 (ankyrin 2); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-Tetrachlorodibenzofuran; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: MODEL
Also known as: Ank3; ankyrin 2, brain; ankyrin 2, neuronal; ankyrin 3, epithelial; ankyrin-2; LOC310885; LOC362036; LOW QUALITY PROTEIN: ankyrin-2
Homo sapiens (human) : ANK2 (ankyrin 2)  HGNC  Alliance
Mus musculus (house mouse) : Ank2 (ankyrin 2, brain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ank2 (ankyrin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ANK2 (ankyrin 2)
Canis lupus familiaris (dog) : ANK2 (ankyrin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ank2 (ankyrin 2)
Sus scrofa (pig) : ANK2 (ankyrin 2)
Chlorocebus sabaeus (African green monkey) : ANK2 (ankyrin 2)
Heterocephalus glaber (naked mole-rat) : Ank2 (ankyrin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02231,224,643 - 231,522,655 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2231,226,949 - 231,648,122 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02250,573,979 - 250,869,144 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42224,182,431 - 224,501,751 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12224,228,885 - 224,376,051 (-)NCBI
Celera2207,699,846 - 207,902,141 (-)NCBICelera
Cytogenetic Map2q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ank2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620156
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.