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Gene: Wnk2 (WNK lysine deficient protein kinase 2) Rattus norvegicus
Symbol: Wnk2
Name: WNK lysine deficient protein kinase 2
Description: Predicted to have chloride channel inhibitor activity; potassium channel inhibitor activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including protein autophosphorylation; regulation of metal ion transport; and regulation of signal transduction. Predicted to localize to cytosol. Biomarker of transient cerebral ischemia. Orthologous to human WNK2 (WNK lysine deficient protein kinase 2); INTERACTS WITH 17beta-estradiol; bisphenol A; nitrofen.
Type: protein-coding
Also known as: kinase deficient protein; LOC306811; RGD1307284; serine/threonine-protein kinase WNK2; similar to protein kinase, lysine deficient 1
Homo sapiens (human) : WNK2 (WNK lysine deficient protein kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Wnk2 (WNK lysine deficient protein kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnk2 (WNK lysine deficient protein kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : WNK2 (WNK lysine deficient protein kinase 2)
Canis lupus familiaris (dog) : WNK2 (WNK lysine deficient protein kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnk2 (WNK lysine deficient protein kinase 2)
Sus scrofa (pig) : WNK2 (WNK lysine deficient protein kinase 2)
Chlorocebus sabaeus (African green monkey) : WNK2 (WNK lysine deficient protein kinase 2)
Heterocephalus glaber (naked mole-rat) : Wnk2 (WNK lysine deficient protein kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01715,923,508 - 16,032,271 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1715,924,048 - 16,032,420 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01717,986,985 - 18,095,251 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41721,461,980 - 21,600,361 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11721,462,134 - 21,600,354 (+)NCBI
Celera1715,234,024 - 15,342,287 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Wnk2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307284
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.