Mir137 (microRNA 137) - Rat Genome Database

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Gene: Mir137 (microRNA 137) Rattus norvegicus
Analyze
Symbol: Mir137
Name: microRNA 137
RGD ID: 2325570
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in several processes, including negative regulation of cell migration; negative regulation of cell population proliferation; and negative regulation of protein metabolic process. Predicted to act upstream of or within several processes, including cellular hyperosmotic salinity response; cellular response to leukemia inhibitory factor; and long-term synaptic potentiation. Orthologous to human MIR137 (microRNA 137); INTERACTS WITH atrazine; cadmium dichloride; resveratrol.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-137; rno-mir-137
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22206,480,881 - 206,480,982 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2206,480,884 - 206,480,985 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2214,135,873 - 214,135,974 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02212,043,267 - 212,043,368 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02206,868,898 - 206,868,999 (+)NCBIRnor_WKY
Rnor_6.02221,658,106 - 221,658,207 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2221,658,106 - 221,658,207 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02239,707,763 - 239,707,864 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2198,952,973 - 198,953,074 (+)NCBICelera
Cytogenetic Map2q41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:16381832   PMID:17028171   PMID:17604727   PMID:20403161   PMID:20439489   PMID:20548288   PMID:21628588   PMID:24866554   PMID:25197371   PMID:25858512   PMID:26095359   PMID:28132879  
PMID:28695984   PMID:29115665   PMID:29257263   PMID:29286063   PMID:29687839   PMID:31210303   PMID:31511494   PMID:31822940   PMID:31961204   PMID:32034930   PMID:32096181   PMID:32432314  
PMID:32594381   PMID:33456665   PMID:33499717   PMID:33808213   PMID:34513987  


Genomics

Comparative Map Data
Mir137
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22206,480,881 - 206,480,982 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2206,480,884 - 206,480,985 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2214,135,873 - 214,135,974 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02212,043,267 - 212,043,368 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02206,868,898 - 206,868,999 (+)NCBIRnor_WKY
Rnor_6.02221,658,106 - 221,658,207 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2221,658,106 - 221,658,207 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02239,707,763 - 239,707,864 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2198,952,973 - 198,953,074 (+)NCBICelera
Cytogenetic Map2q41NCBI
MIR137
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38198,046,070 - 98,046,171 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl198,046,070 - 98,046,171 (-)EnsemblGRCh38hg38GRCh38
GRCh37198,511,626 - 98,511,727 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36198,284,213 - 98,284,314 (-)NCBINCBI36Build 36hg18NCBI36
Celera196,765,320 - 96,765,421 (-)NCBICelera
Cytogenetic Map1p21.3NCBI
HuRef196,633,265 - 96,633,366 (-)NCBIHuRef
CHM1_1198,627,257 - 98,627,358 (-)NCBICHM1_1
T2T-CHM13v2.0197,893,959 - 97,894,060 (-)NCBIT2T-CHM13v2.0
Mir137
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393118,227,506 - 118,227,578 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3118,227,506 - 118,227,578 (+)EnsemblGRCm39 Ensembl
GRCm383118,433,857 - 118,433,929 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3118,433,857 - 118,433,929 (+)EnsemblGRCm38mm10GRCm38
MGSCv373118,136,775 - 118,136,847 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera3124,841,862 - 124,841,934 (+)NCBICelera
Cytogenetic Map3G1NCBI
MIR137
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1651,640,476 - 51,640,530 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl651,640,452 - 51,640,556 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha654,326,370 - 54,326,424 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0651,995,613 - 51,995,667 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1651,687,372 - 51,687,426 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0651,667,446 - 51,667,500 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0652,099,854 - 52,099,908 (+)NCBIUU_Cfam_GSD_1.0
MIR137
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4119,793,984 - 119,794,088 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14119,793,993 - 119,794,074 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24131,567,078 - 131,567,159 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:8681
Count of gene targets:5480
Count of transcripts:5867
Interacting mature miRNAs:rno-miR-137-3p, rno-miR-137-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2185876309219753474Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2185876309219753474Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2189599258218414891Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
2299161Iddm33Insulin dependent diabetes mellitus QTL 332.98blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2206312063220876787Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

endocrine system nervous system reproductive system
High
Medium
Low 1 24 3
Below cutoff 1 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000053614
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2206,480,884 - 206,480,985 (+)Ensembl
Rnor_6.0 Ensembl2221,658,106 - 221,658,207 (+)Ensembl
RefSeq Acc Id: NR_031883
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22206,480,881 - 206,480,982 (+)NCBI
Rnor_6.02221,658,106 - 221,658,207 (+)NCBI
Rnor_5.02239,707,763 - 239,707,864 (+)NCBI
Celera2198,952,973 - 198,953,074 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325570 AgrOrtholog
BioCyc Gene G2FUF-51451 BioCyc
Ensembl Genes ENSRNOG00000035491 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053614 ENTREZGENE
miRBase MI0000910 ENTREZGENE
NCBI Gene 100314031 ENTREZGENE
PhenoGen Mir137 PhenoGen
RNAcentral URS00001E3523 RNACentral
  URS0000759B26 RNACentral
  URS000075D1D8 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir137  microRNA 137  Mir137  microRNA mir-137  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir137  microRNA mir-137      Symbol and Name status set to provisional 70820 PROVISIONAL