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Pathways

RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.

Term:limb reperfusion injury
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Accession:DOID:9001659 term browser browse the term
Definition:This is adverse functional, metabolic, or structural changes in ischemic tissues resulting from the restoration of blood flow to one or more limbs, including swelling; hemorrhage; necrosis; and damage from free radicals. A limb is a paired appendage that is evolved from a paired fin.
Synonyms:narrow_synonym: forelimb reperfusion injury;   hindlimb reperfusion injury



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limb reperfusion injury term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gpt glutamic--pyruvic transaminase treatment IEP RGD PMID:36495512 RGD:401717522 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
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Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14566
    disease of anatomical entity 13676
      cardiovascular system disease 4275
        vascular disease 3427
          Reperfusion Injury 828
            limb reperfusion injury 1
Path 2
Term Annotations click to browse term
  disease 14566
    disease of anatomical entity 13676
      cardiovascular system disease 4275
        vascular disease 3427
          ischemia 1516
            limb ischemia 24
              limb reperfusion injury 1
paths to the root