Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Klrk1 (killer cell lectin like receptor K1) Rattus norvegicus
Symbol: Klrk1
Name: killer cell lectin like receptor K1
Description: Predicted to have several functions, including MHC class I protein binding activity; MHC class Ib receptor activity; and identical protein binding activity. Involved in positive regulation of apoptotic process; positive regulation of myeloid dendritic cell activation; and positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target. Localizes to cell surface. Used to study histiocytoma. Orthologous to several human genes including KLRC4-KLRK1 (KLRC4-KLRK1 readthrough); PARTICIPATES IN malaria pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: killer cell lectin-like receptor subfamily K, member 1; NK cell receptor D; NK lectin-like receptor; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor; NKG2D; NKLLR; NKR-P2, ortholog of human NKG2D; Nkrp2
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04163,392,652 - 163,403,735 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,393,217 - 163,403,653 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04212,035,683 - 212,046,724 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44166,914,786 - 166,922,659 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14167,159,723 - 167,167,595 (-)NCBI
Celera4151,761,022 - 151,771,458 (-)NCBICelera
Cytogenetic Map4q42NCBI
RH 3.4 Map41013.4RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Klrk1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3180
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.