|
Symbol |
Object Name |
Qualifiers |
Evidence |
Notes |
Source |
PubMed Reference(s) |
RGD Reference(s) |
Position |
|
G |
A2m |
alpha-2-macroglobulin |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of A2M mRNA |
CTD |
PMID:2440878 |
|
NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786
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|
G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]; eriodictyol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; kaempferol inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; Quercetin inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]]; withaferin A inhibits the reaction [[ABCB1 protein results in decreased susceptibility to Doxorubicin] promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ABCB1 mRNA]] |
CTD |
PMID:20438634 |
|
NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:25,158,362...25,442,709
|
|
G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
multiple interactions decreases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] |
CTD |
PMID:11331069 |
|
NCBI chr 4:26,106,895...26,164,440
Ensembl chr 4:25,151,953...25,209,202
|
|
G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
decreases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of ABCC1 protein Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC1 protein] |
CTD |
PMID:15517594 PMID:18473823 |
|
NCBI chr10:1,022,041...1,162,431
Ensembl chr10:531,812...655,114
|
|
G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Carbamazepine results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenobarbital results in increased expression of ABCC2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenytoin results in increased expression of ABCC2 protein] |
CTD |
PMID:18473823 |
|
NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:242,664,657...242,723,238
|
|
G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ABCC4 mRNA |
CTD |
PMID:19142964 |
|
NCBI chr15:101,948,387...102,182,912
Ensembl chr15:95,542,315...95,774,283
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|
G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ABL1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 3:35,377,587...35,480,843
Ensembl chr 3:14,979,853...15,083,065
|
|
G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ACACA mRNA |
CTD |
PMID:37055963 |
|
NCBI chr10:69,511,627...69,773,888
Ensembl chr10:69,014,170...69,276,457
|
|
G |
Ace |
angiotensin I converting enzyme |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ACE mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [VEGFA protein results in increased expression of ACE protein] |
CTD |
PMID:11158990 PMID:15071347 |
|
NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131
|
|
G |
Aco1 |
aconitase 1 |
multiple interactions increases activity |
ISO EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of ACO1 protein] Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ACO1 protein] |
CTD |
PMID:10889193 |
|
NCBI chr 5:60,055,895...60,111,920
Ensembl chr 5:55,259,827...55,316,391
|
|
G |
Actb |
actin, beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA |
CTD |
PMID:15477007 |
|
NCBI chr12:16,776,664...16,779,634
Ensembl chr12:11,663,109...11,672,877
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|
G |
Adam12 |
ADAM metallopeptidase domain 12 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM12 mRNA |
CTD |
PMID:16979875 |
|
NCBI chr 1:198,116,968...198,443,680
Ensembl chr 1:188,686,989...189,020,667
|
|
G |
Adam17 |
ADAM metallopeptidase domain 17 |
increases response to substance multiple interactions increases expression |
ISO |
ADAM17 results in increased susceptibility to Tetradecanoylphorbol Acetate ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein] Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]; Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of ADAM17 protein] |
CTD |
PMID:12147693 PMID:23774263 PMID:24632454 PMID:26298005 PMID:28703301 |
|
NCBI chr 6:46,601,583...46,663,690
Ensembl chr 6:40,872,856...40,920,639
|
|
G |
Adam8 |
ADAM metallopeptidase domain 8 |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ADAM8 mRNA Tetradecanoylphorbol Acetate results in increased expression of ADAM8 mRNA |
CTD |
PMID:16979875 PMID:19945525 |
|
NCBI chr 1:204,206,206...204,218,988
Ensembl chr 1:194,770,060...194,788,801
|
|
G |
Adm |
adrenomedullin |
decreases expression |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of ADM mRNA |
CTD |
PMID:11470465 |
|
NCBI chr 1:174,164,178...174,182,372
Ensembl chr 1:164,745,466...164,747,654
|
|
G |
Adora2a |
adenosine A2a receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA2A mRNA |
CTD |
PMID:23519560 |
|
NCBI chr20:13,315,270...13,332,802
Ensembl chr20:13,315,853...13,333,386
|
|
G |
Adora3 |
adenosine A3 receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADORA3 mRNA |
CTD |
PMID:23519560 |
|
NCBI chr 2:196,077,042...196,080,686
Ensembl chr 2:193,388,713...193,392,357
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|
G |
Adra1a |
adrenoceptor alpha 1A |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ADRA1A mRNA |
CTD |
PMID:7900855 |
|
NCBI chr15:45,005,648...45,111,416
Ensembl chr15:40,832,534...40,927,500
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|
G |
Adra1d |
adrenoceptor alpha 1D |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ADRA1D mRNA |
CTD |
PMID:7900855 |
|
NCBI chr 3:139,246,333...139,262,331
Ensembl chr 3:118,793,346...118,809,354
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|
G |
Adra2a |
adrenoceptor alpha 2A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ADRA2A mRNA |
CTD |
PMID:23519560 |
|
NCBI chr 1:263,066,780...263,069,580
Ensembl chr 1:253,060,218...253,064,365
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|
G |
Adrb2 |
adrenoceptor beta 2 |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of ADRB2 protein |
CTD |
PMID:14722251 |
|
NCBI chr18:57,912,760...57,914,802
Ensembl chr18:55,502,903...55,644,512
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|
G |
Afp |
alpha-fetoprotein |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AFP protein |
CTD |
PMID:16368122 |
|
NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,573,412...17,591,480
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|
G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]] |
CTD |
PMID:23541064 |
|
NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA |
CTD |
PMID:19840844 |
|
NCBI chr19:69,426,540...69,447,017
Ensembl chr19:52,529,185...52,540,977
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|
G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions affects response to substance decreases expression increases expression affects localization |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of AHR mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and affects the localization of AHR protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SAA3 mRNA]]; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of AHR protein] AHR protein affects the susceptibility to Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in decreased expression of AHR protein [Tetradecanoylphorbol Acetate co-treated with Tetrachlorodibenzodioxin] results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased localization of and results in increased activity of AHR protein] Tetradecanoylphorbol Acetate results in increased expression of AHR mRNA; Tetradecanoylphorbol Acetate results in increased expression of AHR protein Tetradecanoylphorbol Acetate affects the localization of AHR protein |
CTD |
PMID:1313028 PMID:8390902 PMID:8396892 PMID:9415701 PMID:9706865 PMID:20423157 PMID:23291558 PMID:24481452 More...
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NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568
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G |
Ahrr |
aryl-hydrocarbon receptor repressor |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Methylcholanthrene] results in increased expression of AHRR mRNA Tetradecanoylphorbol Acetate results in increased expression of AHRR mRNA |
CTD |
PMID:11423533 |
|
NCBI chr 1:30,822,219...30,917,251
Ensembl chr 1:28,993,634...29,088,673
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G |
Akr1b10 |
aldo-keto reductase family 1 member B10 |
multiple interactions decreases expression |
ISO |
[Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of AKR1B10 protein |
CTD |
PMID:25463304 PMID:26198647 |
|
NCBI chr 4:64,005,632...64,027,860
Ensembl chr 4:63,040,169...63,053,852
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of AKR1C2 mRNA [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of AKR1C21 mRNA |
CTD |
PMID:18353537 PMID:26198647 |
|
NCBI chr17:70,669,684...70,717,935
Ensembl chr17:65,759,788...65,775,764
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of AKT1 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein cyclosporin H inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:20172950 PMID:20438634 PMID:20660715 PMID:22465218 PMID:25590691 PMID:25866363 PMID:27432484 PMID:30590137 PMID:34144024 More...
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NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921
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G |
Alas1 |
5'-aminolevulinate synthase 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ALAS mRNA |
CTD |
PMID:15797241 |
|
NCBI chr 8:115,755,238...115,768,642
Ensembl chr 8:106,876,514...106,889,917
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G |
Alb |
albumin |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ALB mRNA] |
CTD |
PMID:24211529 |
|
NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,607,381...17,622,836
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|
G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:19840844 |
|
NCBI chr 1:227,426,939...227,579,497
Ensembl chr 1:218,042,127...218,152,961
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|
G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of ALOX5 protein; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of ALOX5 protein |
CTD |
PMID:10779545 PMID:11698504 |
|
NCBI chr 4:151,203,948...151,251,126
Ensembl chr 4:149,531,515...149,578,743
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G |
Anxa1 |
annexin A1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ANXA1 mRNA |
CTD |
PMID:19945525 |
|
NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343
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G |
Anxa10 |
annexin A10 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA10 mRNA |
CTD |
PMID:16979875 |
|
NCBI chr16:32,505,025...32,571,961
Ensembl chr16:27,738,712...27,805,648
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G |
Anxa2 |
annexin A2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ANXA2 protein |
CTD |
PMID:20045496 |
|
NCBI chr 8:78,986,252...79,022,638
Ensembl chr 8:70,105,253...70,141,658
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G |
Anxa3 |
annexin A3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ANXA3 mRNA |
CTD |
PMID:16979875 |
|
NCBI chr14:13,031,675...13,085,678
Ensembl chr14:12,719,795...12,781,617
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G |
Apaf1 |
apoptotic peptidase activating factor 1 |
affects expression |
ISO |
Tetradecanoylphorbol Acetate affects the expression of APAF1 protein |
CTD |
PMID:11139146 |
|
NCBI chr 7:27,381,392...27,466,772
Ensembl chr 7:25,494,609...25,579,540
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
multiple interactions |
ISO |
[ferric chloride co-treated with Tetradecanoylphorbol Acetate] affects the localization of APEX1 protein |
CTD |
PMID:12023366 |
|
NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785
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G |
Apex2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of APEX2 mRNA |
CTD |
PMID:19031421 |
|
NCBI chr X:22,914,943...22,937,713
Ensembl chr X:19,487,419...19,508,439
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G |
Aplp2 |
amyloid beta precursor like protein 2 |
multiple interactions increases secretion |
ISO |
N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of APLP2 protein] |
CTD |
PMID:16279945 |
|
NCBI chr 8:37,857,407...37,920,487
Ensembl chr 8:29,599,230...29,661,855
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of APP mRNA |
CTD |
PMID:19840844 |
|
NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp4 |
aquaporin 4 |
multiple interactions |
EXP |
[phorbol 13-acetate 12-myristate cotreatment with morphine] decreases expression of AQP4 protein in cultured astrocytes |
RGD |
PMID:28341892 |
RGD:597978120 |
NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,507,903...6,524,856
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of AREG mRNA] [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA] |
CTD |
PMID:20660715 PMID:22643241 |
|
NCBI chr14:17,256,384...17,265,641
Ensembl chr14:16,972,187...16,981,535
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|
G |
Arf1 |
ARF GTPase 1 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of ARF1 protein |
CTD |
PMID:10931844 |
|
NCBI chr10:44,497,543...44,513,994
Ensembl chr10:43,997,986...44,014,434
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G |
Arf6 |
ARF GTPase 6 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of ARF6 protein |
CTD |
PMID:10931844 PMID:16280360 |
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NCBI chr 6:93,589,777...93,590,925
Ensembl chr 6:87,840,142...87,874,114
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G |
Arhgap20 |
Rho GTPase activating protein 20 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ARHGAP20 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:60,970,480...61,055,199
Ensembl chr 8:52,074,158...52,155,739
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G |
Arhgef9 |
Cdc42 guanine nucleotide exchange factor 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARHGEF9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:63,929,168...64,087,267
Ensembl chr X:59,920,870...60,077,513
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G |
Arl4c |
ARF like GTPase 4C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ARL4C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:96,748,075...96,751,510
Ensembl chr 9:89,298,005...89,304,513
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G |
Arl6ip5 |
ARF like GTPase 6 interacting protein 5 |
multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Tretinoin results in increased expression of ARL6IP5 mRNA] Tetradecanoylphorbol Acetate results in increased expression of ARL6IP5 protein |
CTD |
PMID:16430862 PMID:16468075 |
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NCBI chr 4:131,365,320...131,395,311
Ensembl chr 4:129,810,645...129,838,608
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein] |
CTD |
PMID:24481452 |
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NCBI chr 2:185,686,703...185,745,546
Ensembl chr 2:182,997,736...183,056,580
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G |
Arpc2 |
actin related protein 2/3 complex, subunit 2 |
multiple interactions |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein] |
CTD |
PMID:15477007 PMID:16027158 |
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NCBI chr 9:83,269,884...83,300,610
Ensembl chr 9:75,820,770...75,851,471
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G |
Art3 |
ADP-ribosyltransferase 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ART3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:15,921,540...16,003,764
Ensembl chr14:15,637,237...15,665,407
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G |
Asf1a |
anti-silencing function 1A histone chaperone |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ASF1A mRNA |
CTD |
PMID:26198647 |
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NCBI chr20:33,436,632...33,451,478
Ensembl chr20:32,893,573...32,908,808
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ASS1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:35,144,765...35,194,632
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 7:113,684,681...113,686,739
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf5 |
activating transcription factor 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ATF5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:104,432,094...104,437,611
Ensembl chr 1:95,295,610...95,299,707
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G |
Atp1b1 |
ATPase Na+/K+ transporting subunit beta 1 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of ATP1B1 mRNA |
CTD |
PMID:11204457 |
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NCBI chr13:79,319,708...79,340,226
Ensembl chr13:76,786,578...76,807,459
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions decreases expression increases activity |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of ATP2A2 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ATP2A2 protein Tetradecanoylphorbol Acetate results in increased activity of ATP2A2 protein |
CTD |
PMID:17003265 PMID:19244478 |
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NCBI chr12:39,733,519...39,782,942
Ensembl chr12:34,072,683...34,122,101
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G |
Atp6v1c2 |
ATPase H+ transporting V1 subunit C2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ATP6V1C2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:45,809,269...45,872,914
Ensembl chr 6:40,080,547...40,120,028
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G |
Atp7a |
ATPase copper transporting alpha |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate results in increased expression of ATP7A protein] which results in increased export of Copper; ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA] |
CTD |
PMID:19205902 |
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NCBI chr X:75,159,635...75,267,094
Ensembl chr X:71,094,202...71,198,354
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G |
Atp7b |
ATPase copper transporting beta |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] which results in increased expression of ATP7B protein |
CTD |
PMID:21189263 |
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NCBI chr16:76,654,725...76,726,092
Ensembl chr16:69,951,778...70,023,636
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G |
Aurka |
aurora kinase A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of AURKA mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:181,546,742...181,562,890
Ensembl chr 3:161,128,313...161,144,390
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G |
Bace1 |
beta-secretase 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] |
CTD |
PMID:23541064 |
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NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:46,142,116...46,165,876
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G |
Bach1 |
BTB domain and CNC homolog 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of BACH1 mRNA |
CTD |
PMID:33268675 |
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NCBI chr11:40,425,721...40,461,118
Ensembl chr11:26,939,480...26,972,447
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions |
ISO |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAD protein |
CTD |
PMID:25446327 |
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NCBI chr 1:213,562,719...213,572,034
Ensembl chr 1:204,131,501...204,142,823
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G |
Bag1 |
BAG cochaperone 1 |
multiple interactions |
ISO |
BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA]; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MT2A mRNA]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] |
CTD |
PMID:20858459 |
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NCBI chr 5:60,864,476...60,877,059
Ensembl chr 5:56,068,494...56,081,075
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BAK1 protein |
CTD |
PMID:11139146 |
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NCBI chr20:5,102,334...5,111,615
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions decreases expression |
ISO EXP |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BAX protein; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein] Tetradecanoylphorbol Acetate results in decreased expression of BAX protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BAX protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in decreased expression of BAX protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of BAX protein] Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in increased expression of BAX protein] |
CTD |
PMID:15748703 PMID:19161993 PMID:22760862 PMID:25446327 PMID:32662567 PMID:36925031 More...
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NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression increases expression |
ISO EXP |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein]]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2 mRNA; edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in decreased expression of BCL2 protein] Tetradecanoylphorbol Acetate results in decreased expression of BCL2 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of BCL2 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in decreased expression of BCL2 protein] Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of BCL2 protein] |
CTD |
PMID:9295281 PMID:11139146 PMID:15538571 PMID:15748703 PMID:16979875 PMID:19161993 PMID:19631781 PMID:22760862 PMID:24073338 PMID:25446327 PMID:32662567 PMID:36075570 PMID:36925031 More...
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NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions increases expression |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of BCL2A1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BCL2A1 mRNA] |
CTD |
PMID:15477007 PMID:16979875 PMID:20438634 |
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NCBI chr 8:98,596,806...98,604,890
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BCL2L1 protein [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BCL2L1 mRNA |
CTD |
PMID:11139146 PMID:18958680 |
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NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479 Ensembl chr 1:141,253,523...141,303,479
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BECN1 protein |
CTD |
PMID:25446327 |
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NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
multiple interactions increases expression |
ISO |
CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BGLAP protein] |
CTD |
PMID:37562720 |
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NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BGN mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:156,348,633...156,360,797
Ensembl chr X:151,197,273...151,209,461
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BHMT mRNA |
CTD |
PMID:16368122 |
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NCBI chr 2:26,594,852...26,614,429
Ensembl chr 2:24,859,873...24,879,742
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G |
Bik |
BCL2-interacting killer |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BIK mRNA |
CTD |
PMID:26198647 |
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NCBI chr 7:116,552,303...116,571,317
Ensembl chr 7:114,672,277...114,691,296
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
affects localization |
ISO |
Tetradecanoylphorbol Acetate affects the localization of BIRC2 protein |
CTD |
PMID:15187025 |
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NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions increases expression |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BIRC3 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] |
CTD |
PMID:14527959 PMID:24849683 PMID:31068361 |
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NCBI chr 8:13,285,702...13,313,329
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BIRC5 mRNA |
CTD |
PMID:19031421 |
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NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380
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G |
Bmi1 |
BMI1 proto-oncogene, polycomb ring finger |
decreases response to substance |
ISO |
BMI1 protein results in decreased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:24571310 |
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NCBI chr17:86,240,683...86,250,044
Ensembl chr17:81,332,214...81,388,690
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G |
Bmp2 |
bone morphogenetic protein 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BMP2 mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP2 mRNA] |
CTD |
PMID:10910055 PMID:21331654 |
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NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of BMP6 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr17:26,523,704...26,785,558
Ensembl chr17:26,318,569...26,470,365
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G |
Bnip3l |
BCL2 interacting protein 3 like |
multiple interactions increases expression |
EXP |
Plicamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BNIP3L mRNA] |
CTD |
PMID:16291751 |
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NCBI chr15:45,350,081...45,373,213
Ensembl chr15:41,174,594...41,197,803
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G |
Braf |
B-Raf proto-oncogene, serine/threonine kinase |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of BRAF protein ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of BRAF protein] |
CTD |
PMID:17114644 |
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NCBI chr 4:69,329,772...69,476,931
Ensembl chr 4:68,384,649...68,510,463
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G |
Brca1 |
BRCA1, DNA repair associated |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of BRCA1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr10:86,917,693...86,978,012
Ensembl chr10:86,418,000...86,477,304
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G |
Bsg |
basigin |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein] Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA; Tetradecanoylphorbol Acetate results in increased expression of BSG protein |
CTD |
PMID:16860414 PMID:17055343 PMID:18647594 |
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NCBI chr 7:10,643,788...10,651,005
Ensembl chr 7:9,993,170...10,000,387
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G |
Bst1 |
bone marrow stromal cell antigen 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of BST1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:71,466,179...71,482,671
Ensembl chr14:67,252,998...67,270,180
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G |
Btg2 |
BTG anti-proliferation factor 2 |
multiple interactions increases expression |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Go 6976] results in increased expression of BTG2 mRNA Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of BTG2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of BTG2 mRNA |
CTD |
PMID:2005087 PMID:15302583 |
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NCBI chr13:48,083,931...48,087,690
Ensembl chr13:45,531,925...45,535,628
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G |
Bub1b |
BUB1 mitotic checkpoint serine/threonine kinase B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of BUB1B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:126,017,019...126,069,470
Ensembl chr 3:105,563,138...105,615,547
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G |
C3h15orf48 |
similar to human chromosome 15 open reading frame 48 |
affects response to substance affects expression |
ISO |
NMES1 affects the susceptibility to Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate affects the expression of NMES1 |
CTD |
PMID:16044405 |
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NCBI chr 3:130,173,535...130,177,088
Ensembl chr 3:109,719,897...109,724,006 Ensembl chr 3:109,719,897...109,724,006
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G |
C4a |
complement C4A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,010,306...4,024,707
Ensembl chr20:4,005,731...4,020,080
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G |
C4b |
complement C4B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of C4B mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,201,979...4,216,292
Ensembl chr20:4,197,366...4,211,681
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G |
C5ar1 |
complement C5a receptor 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of C5AR1 protein |
CTD |
PMID:18559098 |
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NCBI chr 1:86,077,309...86,088,001
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G |
Cacna1g |
calcium voltage-gated channel subunit alpha1 G |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CACNA1G mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:79,851,886...79,919,926
Ensembl chr10:79,355,008...79,422,752
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CALM1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 6:125,217,191...125,227,855
Ensembl chr 6:119,487,621...119,498,227
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CALR mRNA |
CTD |
PMID:19031421 |
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NCBI chr19:40,213,367...40,218,262
Ensembl chr19:23,308,351...23,313,414
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G |
Camk1 |
calcium/calmodulin-dependent protein kinase I |
multiple interactions increases phosphorylation |
ISO |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein]; CAMK1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CAMK1 protein] |
CTD |
PMID:20590612 |
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NCBI chr 4:148,036,843...148,047,675
Ensembl chr 4:146,481,196...146,492,081
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G |
Camk2b |
calcium/calmodulin-dependent protein kinase II beta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAMK2B mRNA |
CTD |
PMID:23519560 |
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NCBI chr14:85,059,166...85,148,121
Ensembl chr14:80,845,238...80,933,994
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G |
Capn11 |
calpain 11 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN11 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:22,841,500...22,863,042
Ensembl chr 9:15,344,089...15,365,601
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G |
Capn6 |
calpain 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CAPN6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr X:112,177,467...112,202,178
Ensembl chr X:107,380,774...107,405,489
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G |
Capn9 |
calpain 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CAPN9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr19:69,446,847...69,483,810
Ensembl chr19:52,549,448...52,586,413
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G |
Car14 |
carbonic anhydrase 14 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CA14 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:186,131,196...186,138,164
Ensembl chr 2:183,441,667...183,449,693
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G |
Car3 |
carbonic anhydrase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CAR3 protein |
CTD |
PMID:20045496 |
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NCBI chr 2:88,491,666...88,501,299
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
[[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased cleavage of CASP1 protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP1 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased activity of CASP1 protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA] |
CTD |
PMID:21515303 PMID:22322153 PMID:23430110 PMID:23535185 PMID:24158569 PMID:26091108 More...
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NCBI chr 8:10,746,338...10,882,295
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP12 protein] |
CTD |
PMID:19631781 |
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NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions decreases expression |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of CASP3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP3 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Trichlorfon results in increased cleavage of and results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased activity of CASP3 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin results in increased activity of CASP3 protein] Tetradecanoylphorbol Acetate results in decreased expression of CASP3 protein |
CTD |
PMID:11139146 PMID:12165276 PMID:14610070 PMID:15538571 PMID:17309078 PMID:19631781 PMID:24073338 PMID:25446327 PMID:32662567 PMID:36075570 More...
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NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CASP8 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP8 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] |
CTD |
PMID:12165276 PMID:15477007 PMID:18958680 |
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NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions decreases expression |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CASP9 protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of and results in increased cleavage of CASP9 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CASP9 protein] Tetradecanoylphorbol Acetate results in decreased expression of CASP9 protein |
CTD |
PMID:17309078 PMID:24073338 PMID:25446327 PMID:32662567 |
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Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions decreases expression decreases activity |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CAT mRNA; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased oxidation of 1,2-diaminobenzene] Tetradecanoylphorbol Acetate results in decreased expression of CAT protein Tetradecanoylphorbol Acetate results in decreased activity of CAT protein [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of CAT protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of CAT protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of CAT protein; [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CAT protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of CAT protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; CAT inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CAT protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of CAT protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CAT protein results in increased metabolism of Hydrogen Peroxide]; Tetradecanoylphorbol Acetate inhibits the reaction [Patulin results in decreased activity of CAT protein] |
CTD |
PMID:2126186 PMID:3030588 PMID:11243714 PMID:12065085 PMID:12504893 PMID:14997284 PMID:16091123 PMID:18958680 PMID:19095747 PMID:19161993 PMID:20691676 PMID:21964610 PMID:22036979 PMID:22760862 PMID:22981962 PMID:23399806 PMID:31351099 PMID:32662567 More...
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NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav3 |
caveolin 3 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of CAV3 mRNA |
CTD |
PMID:15725944 |
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NCBI chr 4:147,137,993...147,153,967
Ensembl chr 4:145,582,060...145,598,137
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G |
Cblif |
cobalamin binding intrinsic factor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CBLIF mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:218,030,756...218,045,004
Ensembl chr 1:208,605,983...208,620,344
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G |
Cbr1 |
carbonyl reductase 1 |
multiple interactions |
ISO |
CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein] |
CTD |
PMID:25818598 |
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NCBI chr11:46,346,405...46,348,815
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Ccl1 |
C-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCL1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:67,625,962...67,628,740
Ensembl chr10:67,128,331...67,131,159
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL11 protein; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL11 mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL11 protein] |
CTD |
PMID:17572062 PMID:17685462 PMID:21331654 |
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NCBI chr10:67,525,975...67,530,576
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression increases secretion |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of CCL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CCL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL2 protein; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; irosustat inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CCL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL2 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of CCL2 protein] Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL2 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL2 protein] |
CTD |
PMID:16376386 PMID:17572062 PMID:17685462 PMID:19063610 PMID:19945525 PMID:20438634 PMID:21035309 PMID:30254419 PMID:30696844 PMID:31217279 PMID:31351099 PMID:31904401 PMID:36416909 More...
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NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCL20 mRNA |
CTD |
PMID:19945525 |
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NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of CCL3 protein] |
CTD |
PMID:15477007 PMID:17572062 PMID:17685462 PMID:36416909 |
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NCBI chr10:68,948,889...68,950,439
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
multiple interactions increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CCL4 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL4 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL4 protein] decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCL4 protein] |
CTD |
PMID:9122163 PMID:17572062 PMID:17685462 PMID:18958680 PMID:31351099 |
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NCBI chr10:68,963,893...68,965,728
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL5 protein; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CCL5 protein] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCL5 mRNA |
CTD |
PMID:17572062 PMID:17685462 PMID:31904401 |
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NCBI chr10:68,820,330...68,824,906
Ensembl chr10:68,322,829...68,327,377
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCN1 mRNA] |
CTD |
PMID:15117851 |
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NCBI chr 2:237,222,730...237,225,689
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:22,621,498...22,624,614
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccna2 |
cyclin A2 |
multiple interactions increases expression decreases expression |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein] Tetradecanoylphorbol Acetate results in increased expression of CCNA2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein Tetradecanoylphorbol Acetate results in decreased expression of CCNA2 protein |
CTD |
PMID:12421932 PMID:15949478 PMID:19031421 |
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NCBI chr 2:121,355,363...121,361,762
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnb1 |
cyclin B1 |
multiple interactions increases expression |
ISO |
PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA] |
CTD |
PMID:10866668 PMID:19000923 |
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NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:31,912,193...31,921,172
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G |
Ccnb2 |
cyclin B2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCNB2 mRNA [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CCNB2 mRNA |
CTD |
PMID:16979875 PMID:19031421 |
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NCBI chr 8:79,968,459...79,981,717
Ensembl chr 8:71,087,595...71,100,874
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G |
Ccnd1 |
cyclin D1 |
multiple interactions increases expression decreases expression |
ISO |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of CCND1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CCND1 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CCND1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of CCND1 protein] Tetradecanoylphorbol Acetate results in decreased expression of CCND1 protein |
CTD |
PMID:15949478 PMID:16368122 PMID:18922899 PMID:20438634 PMID:21375462 PMID:24073338 PMID:26537528 PMID:32662567 More...
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NCBI chr 1:209,518,288...209,527,986
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd3 |
cyclin D3 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCND3 protein] |
CTD |
PMID:12421932 |
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NCBI chr 9:20,891,696...20,987,199
Ensembl chr 9:13,394,169...13,489,371
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G |
Ccne1 |
cyclin E1 |
multiple interactions increases expression |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein] |
CTD |
PMID:12421932 PMID:24073338 |
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NCBI chr 1:99,918,672...99,927,986
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccng1 |
cyclin G1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr10:25,678,503...25,684,876
Ensembl chr10:25,176,234...25,181,641
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:84,302,621...84,313,773
Ensembl chr 2:82,590,630...82,602,930
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G |
Cd14 |
CD14 molecule |
multiple interactions increases expression |
ISO |
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD14 protein] Tetradecanoylphorbol Acetate results in increased expression of CD14 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD14 protein |
CTD |
PMID:16430862 PMID:19135038 PMID:20089671 PMID:26036281 PMID:30218697 PMID:33268675 PMID:34506768 More...
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NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261
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G |
Cd200 |
Cd200 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:68,916,200...68,943,570
Ensembl chr11:55,410,196...55,501,648
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G |
Cd28 |
Cd28 molecule |
multiple interactions increases expression |
ISO |
Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Magnesium Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of CD28 protein |
CTD |
PMID:8662792 PMID:11465111 |
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NCBI chr 9:69,660,316...69,689,192
Ensembl chr 9:62,166,192...62,194,685
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G |
Cd302 |
CD302 molecule |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CD302 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:65,131,017...65,164,737
Ensembl chr 3:44,722,325...44,756,045
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G |
Cd34 |
CD34 molecule |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 mRNA; [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of CD34 protein Tetradecanoylphorbol Acetate results in increased expression of CD34 protein |
CTD |
PMID:18922899 |
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NCBI chr13:109,008,786...109,029,317
Ensembl chr13:106,480,043...106,499,832
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G |
Cd36 |
CD36 molecule |
decreases expression increases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of CD36 mRNA Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD36 protein tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA] 2-chloro-5-nitrobenzanilide inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; [15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 mRNA; [Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; [titanium dioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CD36 protein; [Zinc Oxide analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; bisdemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; Dibutyl Phthalate inhibits the reaction [[Rosiglitazone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [[15-deoxyprostaglandin J2 co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD36 protein]; Dibutyl Phthalate promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 protein]; tamibarotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]] |
CTD |
PMID:12664607 PMID:16407258 PMID:16484594 PMID:21315065 PMID:23386263 PMID:24746987 PMID:30218697 PMID:32649966 PMID:34506768 PMID:37055963 More...
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NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd3e |
CD3 epsilon subunit of T-cell receptor complex |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3E protein] |
CTD |
PMID:2824607 |
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NCBI chr 8:54,200,617...54,211,770
Ensembl chr 8:45,303,852...45,315,022
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G |
Cd3g |
CD3 gamma subunit of T-cell receptor complex |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [aluminum fluoride results in increased phosphorylation of CD3G protein] |
CTD |
PMID:2824607 |
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NCBI chr 8:54,177,572...54,184,087
Ensembl chr 8:45,281,204...45,287,147
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G |
Cd4 |
Cd4 molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:159,355,147...159,381,636
Ensembl chr 4:157,668,878...157,695,191
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G |
Cd40 |
CD40 molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD40 mRNA; Apigenin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; fisetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein]; Luteolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD40 protein]; Quercetin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD40 protein] |
CTD |
PMID:16601352 PMID:16979875 |
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NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534
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G |
Cd40lg |
CD40 ligand |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD40LG protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD40LG protein |
CTD |
PMID:11297035 PMID:22851303 |
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NCBI chr X:140,164,341...140,176,057
Ensembl chr X:135,126,969...135,138,306
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G |
Cd44 |
CD44 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA Chlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein; Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CD44 protein binds to Hyaluronic Acid]]; Verapamil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of CD44 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] |
CTD |
PMID:9929743 PMID:15477007 |
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NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd68 |
Cd68 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD68 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD68 protein |
CTD |
PMID:25128825 PMID:28720485 PMID:31011801 |
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NCBI chr10:54,880,562...54,882,441
Ensembl chr10:54,381,815...54,383,697
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G |
Cd69 |
Cd69 molecule |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD69 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CD69 protein 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD69 protein; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CD69 protein] |
CTD |
PMID:12749906 PMID:17962511 PMID:23134680 PMID:23941771 PMID:26343699 PMID:30171972 PMID:31068361 More...
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NCBI chr 4:164,411,485...164,419,403
Ensembl chr 4:162,725,446...162,733,542
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G |
Cd80 |
Cd80 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD80 protein |
CTD |
PMID:30218697 |
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NCBI chr11:75,760,073...75,798,978
Ensembl chr11:62,254,624...62,292,030
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G |
Cd83 |
CD83 molecule |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD83 mRNA |
CTD |
PMID:31068361 |
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NCBI chr17:21,093,281...21,113,223
Ensembl chr17:20,887,309...20,907,083
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G |
Cd9 |
CD9 molecule |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CD9 protein [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CD9 mRNA [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CD9 mRNA |
CTD |
PMID:10910098 PMID:16979875 PMID:19840844 |
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NCBI chr 4:159,942,553...159,975,463
Ensembl chr 4:158,256,328...158,289,222
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G |
Cdc20 |
cell division cycle 20 |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDC20 mRNA Tetradecanoylphorbol Acetate results in increased expression of CDC20 mRNA |
CTD |
PMID:16979875 PMID:19031421 |
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NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc25b |
cell division cycle 25B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CDC25B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:138,860,148...138,870,287
Ensembl chr 3:118,407,128...118,417,272
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G |
Cdc25c |
cell division cycle 25C |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of CDC25C protein |
CTD |
PMID:21375462 |
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NCBI chr18:26,608,483...26,630,292
Ensembl chr18:26,335,834...26,356,185
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDH1 protein] |
CTD |
PMID:25656647 |
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NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh17 |
cadherin 17 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:30,024,544...30,112,226
Ensembl chr 5:25,262,758...25,314,884
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G |
Cdh2 |
cadherin 2 |
multiple interactions increases expression |
ISO |
antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein] morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDH2 protein] |
CTD |
PMID:25656647 PMID:28108223 |
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NCBI chr18:8,051,097...8,265,288
Ensembl chr18:7,776,704...7,990,167
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G |
Cdh5 |
cadherin 5 |
multiple interactions increases phosphorylation |
ISO |
HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein] |
CTD |
PMID:24211779 |
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NCBI chr19:821,875...860,931
Ensembl chr19:815,411...854,368
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G |
Cdk1 |
cyclin-dependent kinase 1 |
multiple interactions decreases expression increases expression |
ISO |
corosolic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDK1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA] |
CTD |
PMID:10866668 PMID:32135139 |
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NCBI chr20:19,265,252...19,280,456
Ensembl chr20:19,266,248...19,281,408
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G |
Cdk2 |
cyclin dependent kinase 2 |
increases activity increases expression multiple interactions decreases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein Tetradecanoylphorbol Acetate results in increased expression of CDK2 protein Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of CDK2 protein] Tetradecanoylphorbol Acetate results in decreased phosphorylation of CDK2 protein |
CTD |
PMID:12421932 PMID:15978937 PMID:24073338 |
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NCBI chr 7:1,714,392...1,721,964
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CDK4 mRNA Tetradecanoylphorbol Acetate results in increased expression of CDK4 protein PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA] |
CTD |
PMID:10866668 PMID:15978937 PMID:24073338 |
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NCBI chr 7:64,771,453...64,774,891
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdk6 |
cyclin-dependent kinase 6 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CDK6 protein |
CTD |
PMID:24073338 |
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NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Atrazine promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; MAPK8 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Tetradecanoylphorbol Acetate promotes the reaction [Atrazine results in increased expression of CDKN1A mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [SP1 protein binds to CDKN1A promoter] Tetradecanoylphorbol Acetate results in increased expression of CDKN1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein |
CTD |
PMID:9348195 PMID:10910055 PMID:15735102 PMID:15976015 PMID:15978937 PMID:18223691 PMID:18958680 PMID:19945525 PMID:23715767 PMID:24211529 More...
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NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in increased expression of CDKN1B protein] Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN1B protein] |
CTD |
PMID:12421932 PMID:26537528 |
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NCBI chr 4:169,491,273...169,496,500
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn1c |
cyclin-dependent kinase inhibitor 1C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN1C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:208,084,801...208,087,680
Ensembl chr 1:198,655,407...198,658,048
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CDKN2A mRNA [arsenic trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CDKN2A mRNA |
CTD |
PMID:16368122 PMID:18922899 |
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NCBI chr 5:109,100,763...109,114,448
Ensembl chr 5:103,984,949...104,003,149
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G |
Cdkn2b |
cyclin-dependent kinase inhibitor 2B |
multiple interactions |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CDKN2B protein] |
CTD |
PMID:12421932 |
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NCBI chr 5:109,123,308...109,134,906
Ensembl chr 5:104,010,680...104,019,050
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G |
Cdkn2c |
cyclin-dependent kinase inhibitor 2C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN2C mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:124,411,124...124,416,278
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CEBPA mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:96,896,584...96,899,256
Ensembl chr 1:87,759,433...87,762,412
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions decreases expression |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of CEBPB protein] Tetradecanoylphorbol Acetate results in decreased expression of CEBPB mRNA |
CTD |
PMID:19282384 PMID:33268675 |
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NCBI chr 3:176,817,005...176,818,436
Ensembl chr 3:156,397,052...156,399,473
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G |
Cfh |
complement factor H |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CFH mRNA |
CTD |
PMID:31904401 |
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NCBI chr13:54,063,079...54,164,523
Ensembl chr13:51,511,828...51,613,838
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G |
Cga |
glycoprotein hormones, alpha polypeptide |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of CGA mRNA |
CTD |
PMID:21467749 |
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NCBI chr 5:54,283,109...54,295,464
Ensembl chr 5:49,487,068...49,499,191
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G |
Chat |
choline O-acetyltransferase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CHAT mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:7,663,665...7,723,416
Ensembl chr16:7,657,362...7,717,093
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G |
Chek1 |
checkpoint kinase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CHEK1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 8:44,609,417...44,629,867
Ensembl chr 8:36,420,569...36,441,009
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G |
Chrnb1 |
cholinergic receptor nicotinic beta 1 subunit |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CHRNB1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:54,999,943...55,015,137
Ensembl chr10:54,501,093...54,516,345
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions increases expression increases phosphorylation increases activity |
ISO |
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CHUK protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of CHUK protein; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein] 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein; Auranofin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of CHUK protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CHUK protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CHUK protein] |
CTD |
PMID:10820281 PMID:15498850 PMID:16474181 PMID:21035309 PMID:23899529 PMID:26220752 PMID:31351099 More...
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NCBI chr 1:252,908,748...252,944,273
Ensembl chr 1:242,959,760...242,995,065
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G |
Cks2 |
CDC28 protein kinase regulatory subunit 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CKS2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr17:13,722,360...13,727,519
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G |
Cldn4 |
claudin 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CLDN4 mRNA |
CTD |
PMID:19945525 |
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NCBI chr12:27,388,160...27,389,958
Ensembl chr12:21,751,331...21,753,436
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G |
Cln3 |
CLN3 lysosomal/endosomal transmembrane protein, battenin |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:190,586,649...190,600,034
Ensembl chr 1:181,156,073...181,167,434
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G |
Clta |
clathrin, light chain A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CLTA mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:63,022,046...63,059,223
Ensembl chr 5:58,245,442...58,263,472
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G |
Cmah |
cytidine monophospho-N-acetylneuraminic acid hydroxylase |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMAHP mRNA |
CTD |
PMID:16979875 |
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NCBI chr17:40,985,129...41,070,317
Ensembl chr17:40,583,667...40,642,275
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G |
Cmklr1 |
chemerin chemokine-like receptor 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CMKLR1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr12:48,634,929...48,687,833
Ensembl chr12:42,974,410...43,028,129
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G |
Cnn1 |
calponin 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CNN1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CNN1 protein |
CTD |
PMID:15380616 |
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NCBI chr 8:28,908,437...28,917,099
Ensembl chr 8:20,632,338...20,641,098
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G |
Cntn6 |
contactin 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CNTN6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:138,911,090...139,307,339
Ensembl chr 4:137,355,367...137,751,119
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL11A1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:204,509,136...204,702,264
Ensembl chr 2:201,820,715...202,013,853
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of COL1A2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of COL1A2 mRNA [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL1A2 mRNA |
CTD |
PMID:16979875 PMID:18922899 PMID:19840844 |
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NCBI chr 4:33,518,557...33,553,484
Ensembl chr 4:32,563,381...32,598,867
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of COL2A1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:130,977,561...131,006,627
Ensembl chr 7:129,098,786...129,127,546
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G |
Col6a1 |
collagen type VI alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL6A1 mRNA [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] |
CTD |
PMID:15477007 PMID:19840844 |
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NCBI chr20:11,905,690...11,924,111
Ensembl chr20:11,905,957...11,924,597
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of COL8A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:56,245,998...56,378,586
Ensembl chr11:42,777,628...42,906,424
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G |
Comt |
catechol-O-methyltransferase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA |
CTD |
PMID:15477007 |
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NCBI chr11:96,072,371...96,091,956
Ensembl chr11:82,568,025...82,587,642
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G |
Coro1b |
coronin 1B |
multiple interactions increases phosphorylation affects response to substance |
EXP ISO |
Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein]]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CORO1B protein]; Tetradecanoylphorbol Acetate inhibits the reaction [CORO1B protein binds to ARPC2 protein] CORO1B protein modified form affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:16027158 |
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NCBI chr 1:210,872,437...210,877,876
Ensembl chr 1:201,443,014...201,448,416
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G |
Cox6a1 |
cytochrome c oxidase subunit 6A1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX6A1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr12:46,922,709...46,925,762
Ensembl chr12:41,261,967...41,265,041
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G |
Cox8a |
cytochrome c oxidase subunit 8A |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of COX8A mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:213,831,302...213,833,623
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions increases phosphorylation increases activity |
ISO |
GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein] [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of CREB1 protein modified form]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter] Tetradecanoylphorbol Acetate results in increased activity of CREB1 protein |
CTD |
PMID:10601319 PMID:18791200 PMID:19282384 PMID:20032081 PMID:21047949 PMID:31068361 PMID:35608139 More...
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NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816
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G |
Crebbp |
CREB binding protein |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter] |
CTD |
PMID:16474181 PMID:19282384 PMID:21047949 |
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NCBI chr10:11,842,307...11,968,266
Ensembl chr10:11,335,953...11,461,888
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G |
Crem |
cAMP responsive element modulator |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:58,932,011...59,001,160
Ensembl chr17:54,239,030...54,305,989
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G |
Crlf2 |
cytokine receptor-like factor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CRLF2 mRNA] |
CTD |
PMID:29462589 |
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NCBI chr14:118,932...123,632
Ensembl chr14:103,939...108,642
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G |
Crp |
C-reactive protein |
multiple interactions |
EXP |
CRP protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides] |
CTD |
PMID:9767445 |
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NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178
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G |
Crtam |
cytotoxic and regulatory T cell molecule |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CRTAM mRNA |
CTD |
PMID:16979875 |
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NCBI chr 8:50,237,210...50,274,472
Ensembl chr 8:41,340,837...41,377,343
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G |
Cry1 |
cryptochrome circadian regulator 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CRY1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 7:20,417,526...20,481,791
Ensembl chr 7:18,529,823...18,594,091
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CSF2 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF2 mRNA; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CSF2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CSF2 protein] Tetradecanoylphorbol Acetate results in increased expression of CSF2 protein 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CSF2 protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of CSF2 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF2 protein] |
CTD |
PMID:1376361 PMID:11752025 PMID:16979875 PMID:17051331 PMID:17572062 PMID:17685462 More...
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NCBI chr10:38,887,692...38,889,673
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CSF3 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CSF3 mRNA |
CTD |
PMID:9122163 PMID:16979875 |
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NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603
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G |
Ctbp1 |
C-terminal binding protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr14:81,679,956...81,707,331
Ensembl chr14:77,455,696...77,482,821
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [CDH5 protein binds to CTNNB1 protein] |
CTD |
PMID:24211779 |
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NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsb |
cathepsin B |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CTSB mRNA |
CTD |
PMID:19840844 |
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NCBI chr15:41,565,607...41,586,479
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsd |
cathepsin D |
decreases cleavage |
ISO |
Tetradecanoylphorbol Acetate results in decreased cleavage of CTSD protein |
CTD |
PMID:36070022 |
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NCBI chr 1:206,956,945...206,968,821
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsg |
cathepsin G |
increases secretion affects localization |
ISO |
Tetradecanoylphorbol Acetate results in increased secretion of CTSG protein Tetradecanoylphorbol Acetate affects the localization of CTSG protein |
CTD |
PMID:25980585 PMID:34144024 |
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NCBI chr15:33,901,230...33,907,596
Ensembl chr15:29,931,003...29,937,353
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G |
Ctsh |
cathepsin H |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CTSH mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:99,488,756...99,507,639
Ensembl chr 8:90,608,941...90,627,824
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G |
Ctsl |
cathepsin L |
multiple interactions decreases cleavage |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CTSL mRNA Tetradecanoylphorbol Acetate results in decreased cleavage of CTSL protein |
CTD |
PMID:19840844 PMID:36070022 |
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NCBI chr17:770,104...776,266
Ensembl chr17:764,309...770,548
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G |
Cul5 |
cullin 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:62,909,150...62,974,641
Ensembl chr 8:54,016,006...54,066,666
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CX3CL1 mRNA |
CTD |
PMID:19850645 |
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NCBI chr19:10,233,326...10,244,856
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA |
CTD |
PMID:9122163 |
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NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions decreases expression |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL10 mRNA; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA] |
CTD |
PMID:22359662 PMID:23519560 |
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NCBI chr14:15,989,066...15,991,263
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CXCL12 mRNA] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL12 mRNA |
CTD |
PMID:22643241 PMID:23519560 |
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NCBI chr 4:152,060,781...152,073,628
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl16 |
C-X-C motif chemokine ligand 16 |
multiple interactions decreases expression |
ISO |
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA] |
CTD |
PMID:22359662 |
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NCBI chr10:55,665,355...55,669,950
Ensembl chr10:55,166,723...55,171,592
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of CXCL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of CXCL2 protein |
CTD |
PMID:20852150 PMID:26513295 PMID:31351099 |
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NCBI chr14:17,465,210...17,467,255
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL1 mRNA Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA] |
CTD |
PMID:9122163 PMID:20172950 PMID:22359662 PMID:26513295 |
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NCBI chr14:17,571,900...17,573,624
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CXCL6 mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CXCL5 mRNA |
CTD |
PMID:16979875 PMID:23519560 |
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NCBI chr14:17,594,959...17,596,417
Ensembl chr14:17,310,426...17,313,093
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
multiple interactions decreases expression |
ISO |
IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA] |
CTD |
PMID:22359662 |
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NCBI chr14:16,007,166...16,012,077
Ensembl chr14:15,722,908...15,728,435
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
multiple interactions increases expression |
ISO |
[Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR1 protein; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA] |
CTD |
PMID:15265017 PMID:21045076 |
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NCBI chr 9:83,216,040...83,220,225
Ensembl chr 9:75,766,770...75,771,084
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
multiple interactions |
ISO |
[Ionophores co-treated with Tetradecanoylphorbol Acetate] results in decreased localization of CXCR2 protein |
CTD |
PMID:15265017 |
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NCBI chr 9:83,178,645...83,185,017
Ensembl chr 9:75,729,115...75,739,425
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G |
Cyba |
cytochrome b-245 alpha chain |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBA mRNA] |
CTD |
PMID:11172467 PMID:20523355 PMID:21705328 |
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NCBI chr19:67,396,143...67,404,214
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
multiple interactions increases activity increases expression |
ISO |
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYBB mRNA] diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of CYBB protein] |
CTD |
PMID:9794432 PMID:29183754 |
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NCBI chr X:16,030,596...16,065,065
Ensembl chr X:13,359,430...13,392,586
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein] |
CTD |
PMID:15748703 |
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NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of CYP11A1 protein |
CTD |
PMID:18755854 PMID:18787026 |
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NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CYP11B2 mRNA |
CTD |
PMID:15666830 |
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NCBI chr 7:108,689,319...108,694,808
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp19a1 |
cytochrome P450, family 19, subfamily a, polypeptide 1 |
multiple interactions decreases activity |
ISO |
[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA; alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA] Tetradecanoylphorbol Acetate results in decreased activity of CYP19A1 protein |
CTD |
PMID:10338361 PMID:16357189 |
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NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression decreases expression affects response to substance |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP1A1 protein; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1A1 protein results in increased abundance of 2-Methoxyestradiol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of CYP1A1 protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CYP1A1 protein; ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CYP1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [benzotriphenylene results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [6-(4-diethylamino)phenyl-7-chloro-5,8-quinolinedione results in increased expression of CYP1A1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Copper inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]] CYP1A1 protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:1313028 PMID:1497680 PMID:8242868 PMID:8396892 PMID:9415701 PMID:9706865 PMID:11710520 PMID:11728381 PMID:18078826 PMID:18958680 PMID:22643241 PMID:24481452 More...
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NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer] Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:1313028 PMID:10620351 |
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NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions decreases expression |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased abundance of 4-methoxyestradiol]]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1B1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of CYP1B1 mRNA chelerythrine promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [CYP1B1 protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene]]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:9706865 PMID:10037446 PMID:11728381 |
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NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] |
CTD |
PMID:20206692 |
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NCBI chr 3:179,694,647...179,709,083
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp27b1 |
cytochrome P450, family 27, subfamily b, polypeptide 1 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CYP27B1 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 7:64,756,626...64,761,570
Ensembl chr 7:62,871,297...62,876,241
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
ISO |
Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate inhibits the reaction [Cycloheximide inhibits the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased oxidation of 4-nitrophenol]; Tetradecanoylphorbol Acetate promotes the reaction [CYP2E1 protein results in increased susceptibility to Ethanol] Tetradecanoylphorbol Acetate results in increased expression of CYP2E1 protein |
CTD |
PMID:8531136 PMID:8798623 PMID:9143349 |
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NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP2F2 mRNA |
CTD |
PMID:16368122 |
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NCBI chr 1:91,543,768...91,557,553
Ensembl chr 1:82,416,130...82,429,896
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions decreases expression decreases activity |
ISO EXP |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of CYP7B1 mRNA Tetradecanoylphorbol Acetate results in decreased expression of CYP7B1 mRNA Tetradecanoylphorbol Acetate results in decreased activity of CYP7B1 protein |
CTD |
PMID:12029625 PMID:16368122 |
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NCBI chr 2:102,419,011...102,586,047
Ensembl chr 2:100,502,791...100,669,698
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G |
Dapk1 |
death associated protein kinase 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DAPK1 mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DAPK1 mRNA |
CTD |
PMID:10910055 PMID:23519560 |
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NCBI chr17:3,935,826...4,096,858
Ensembl chr17:3,930,213...4,090,991
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G |
Dapk2 |
death-associated protein kinase 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DAPK2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 8:75,601,621...75,720,619
Ensembl chr 8:66,706,609...66,825,567
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G |
Dct |
dopachrome tautomerase |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT mRNA]; trichostatin A inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DCT protein] |
CTD |
PMID:15892717 |
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NCBI chr15:101,469,159...101,508,029
Ensembl chr15:95,062,003...95,100,836
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G |
Defb5 |
defensin beta 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein; Ceftaroline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in decreased secretion of DEFB4A protein] |
CTD |
PMID:28720485 |
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NCBI chr16:77,315,424...77,317,828
Ensembl chr16:70,613,146...70,615,467
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G |
Dio3 |
iodothyronine deiodinase 3 |
increases activity multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein Hydrogen Peroxide promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of DIO3 protein] |
CTD |
PMID:16935842 PMID:18420745 |
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NCBI chr 6:135,107,072...135,108,933
Ensembl chr 6:129,285,749...129,286,660
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G |
Dkk2 |
dickkopf WNT signaling pathway inhibitor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DKK2 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 2:223,242,375...223,334,249
Ensembl chr 2:220,568,338...220,660,225
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G |
Dlg1 |
discs large MAGUK scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of DLG1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:82,416,853...82,607,797
Ensembl chr11:68,911,883...69,102,689
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
affects response to substance |
ISO |
DLK1 protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:18575777 |
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NCBI chr 6:134,192,491...134,199,779
Ensembl chr 6:128,410,316...128,417,522
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G |
Dmp1 |
dentin matrix acidic phosphoprotein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DMP1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr14:5,833,111...5,867,154
Ensembl chr14:5,528,431...5,539,323
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DNAJB9 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 6:66,997,842...67,007,371
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:10652249 |
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NCBI chr15:102,432,667...102,475,643
Ensembl chr15:96,025,624...96,065,181
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G |
Dner |
delta/notch-like EGF repeat containing |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of DNER mRNA |
CTD |
PMID:31904401 |
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NCBI chr 9:93,035,108...93,350,568
Ensembl chr 9:85,586,987...85,902,637
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein] |
CTD |
PMID:23775084 |
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NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:19,440,611...19,486,659
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G |
Dock8 |
dedicator of cytokinesis 8 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of DOCK8 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 1:232,075,468...232,268,830
Ensembl chr 1:222,649,309...222,842,474
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G |
Dpyd |
dihydropyrimidine dehydrogenase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DPYD mRNA |
CTD |
PMID:15705907 |
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NCBI chr 2:209,293,902...210,159,777
Ensembl chr 2:206,609,122...207,474,982
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G |
Dusp1 |
dual specificity phosphatase 1 |
multiple interactions increases expression |
ISO |
[Fluticasone co-treated with Tetradecanoylphorbol Acetate] results in increased expression of DUSP1 mRNA; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of DUSP1 mRNA] |
CTD |
PMID:15860753 PMID:20858459 PMID:31068361 |
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NCBI chr10:17,184,853...17,187,646
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G |
Dusp13b |
dual specificity phosphatase 13B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DUSP13B mRNA |
CTD |
PMID:19031421 |
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NCBI chr15:2,616,761...2,624,434
Ensembl chr15:2,533,547...2,575,539
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G |
Dusp2 |
dual specificity phosphatase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of DUSP2 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 3:135,009,636...135,011,821
Ensembl chr 3:114,556,325...114,558,499
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G |
Dusp22 |
dual specificity phosphatase 22 |
decreases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of DUSP22 gene] |
CTD |
PMID:32135139 |
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NCBI chr17:33,989,637...34,040,021
Ensembl chr17:33,780,981...33,831,321
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G |
Dusp4 |
dual specificity phosphatase 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr16:64,079,893...64,101,396
Ensembl chr16:57,377,229...57,398,138
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G |
E2f4 |
E2F transcription factor 4 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; E2F4 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein] |
CTD |
PMID:20479004 |
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NCBI chr19:50,084,335...50,091,731
Ensembl chr19:33,174,410...33,181,806
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G |
Eea1 |
early endosome antigen 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] |
CTD |
PMID:22683840 |
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NCBI chr 7:32,441,281...32,608,808
Ensembl chr 7:30,554,552...30,718,487
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G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EEF1A1 protein |
CTD |
PMID:20045496 |
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NCBI chr 8:88,221,839...88,225,688
Ensembl chr 8:79,341,557...79,344,839
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G |
Eef2 |
eukaryotic translation elongation factor 2 |
multiple interactions |
ISO |
phorbol 13-acetate 12-myristate inhibits the reaction [carbachol decreases phosphorylation of EEF2 protein in colon cancer cells] and decreases phosphorylation of EEF2 protein in colon cancer cells |
RGD |
PMID:31227218 |
RGD:153298919 |
NCBI chr 7:9,183,836...9,196,255
Ensembl chr 7:8,533,116...8,559,183
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G |
Efemp1 |
EGF containing fibulin extracellular matrix protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of EFEMP1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr14:106,811,769...106,890,961
Ensembl chr14:102,610,908...102,690,018
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G |
Efna4 |
ephrin A4 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EFNA4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:177,046,463...177,050,713
Ensembl chr 2:174,748,724...174,752,979
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G |
Egf |
epidermal growth factor |
multiple interactions increases expression |
ISO EXP |
pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGF protein] Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein] bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; TAPI-2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of EGF protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein; Zinc inhibits the reaction [Phenanthrolines inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EGF protein]] |
CTD |
PMID:6309801 PMID:12947092 PMID:19447859 |
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NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases expression increases phosphorylation |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of AREG mRNA]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of AKT1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [EGF protein binds to EGFR protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]] Tetradecanoylphorbol Acetate results in increased expression of EGFR mRNA Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein Tetradecanoylphorbol Acetate results in increased expression of EGFR protein naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] |
CTD |
PMID:6309801 PMID:10516208 PMID:19447859 PMID:20660715 PMID:25866363 PMID:26100520 PMID:26513295 More...
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NCBI chr14:95,378,626...95,551,358
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions increases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; EGR1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein] Tetradecanoylphorbol Acetate results in increased expression of EGR1 mRNA Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of EGR1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter] Tetradecanoylphorbol Acetate results in increased expression of EGR1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein |
CTD |
PMID:2005087 PMID:10693946 PMID:10739673 PMID:10779383 PMID:10910055 PMID:15920718 PMID:19945525 PMID:20479004 PMID:23715767 PMID:31068361 More...
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NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
multiple interactions increases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of EGR2 mRNA |
CTD |
PMID:15477007 PMID:31068361 |
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NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,051,277...21,055,562
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G |
Egr3 |
early growth response 3 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] |
CTD |
PMID:16091474 |
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NCBI chr15:51,560,482...51,565,778
Ensembl chr15:45,150,567...45,154,627
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G |
Egr4 |
early growth response 4 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EGR4 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 4:119,605,358...119,607,817
Ensembl chr 4:118,047,869...118,050,328
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G |
Eif1 |
eukaryotic translation initiation factor 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:85,747,064...85,749,447
Ensembl chr10:85,246,764...85,427,327 Ensembl chr 5:85,246,764...85,427,327
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G |
Eif2ak2 |
eukaryotic translation initiation factor 2-alpha kinase 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF2AK2 protein |
CTD |
PMID:30218697 |
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NCBI chr 6:21,941,147...21,977,115
Ensembl chr 6:16,188,979...16,224,971
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G |
Eif4a1 |
eukaryotic translation initiation factor 4A1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EIF4A1 mRNA |
CTD |
PMID:31068361 |
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NCBI chr10:54,883,093...54,888,602
Ensembl chr10:54,384,347...54,389,858
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G |
Eif4e |
eukaryotic translation initiation factor 4E |
multiple interactions increases phosphorylation |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; CGP 57380 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]; SB 203580 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4E protein] |
CTD |
PMID:9545260 PMID:12781867 |
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NCBI chr 2:229,736,309...229,772,628
Ensembl chr 2:227,066,673...227,098,683
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G |
Eif4e1b |
eukaryotic translation initiation factor 4E family member 1B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EIF4E1B mRNA |
CTD |
PMID:23519560 |
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NCBI chr17:9,835,883...9,868,781
Ensembl chr17:9,832,230...9,835,137
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [EIF4EBP1 protein binds to EIF4E protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4EBP1 protein |
CTD |
PMID:12781867 |
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NCBI chr16:71,495,457...71,508,845
Ensembl chr16:64,790,226...64,805,984
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G |
Eif4g1 |
eukaryotic translation initiation factor 4 gamma 1 |
multiple interactions |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of EIF4G1 protein] |
CTD |
PMID:12781867 |
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NCBI chr11:93,726,322...93,746,387
Ensembl chr11:80,221,919...80,241,941
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G |
Eif4g2 |
eukaryotic translation initiation factor 4, gamma 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of EIF4G2 protein |
CTD |
PMID:18491231 |
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NCBI chr 1:174,616,102...174,628,252
Ensembl chr 1:165,181,434...165,193,588
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G |
Eif5 |
eukaryotic translation initiation factor 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of EIF5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:136,410,333...136,418,827
Ensembl chr 6:130,589,143...130,597,656
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G |
Elk1 |
ETS transcription factor ELK1 |
increases activity increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of ELK1 protein Tetradecanoylphorbol Acetate results in increased phosphorylation of ELK1 protein |
CTD |
PMID:18791200 PMID:21375462 |
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NCBI chr X:3,692,367...3,709,252
Ensembl chr X:1,139,756...1,155,713
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G |
Elmo1 |
engulfment and cell motility 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ELMO1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr17:48,982,188...49,518,525
Ensembl chr17:44,286,485...44,822,788
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G |
Eln |
elastin |
multiple interactions decreases expression |
EXP |
[Okadaic Acid co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ELN mRNA Tetradecanoylphorbol Acetate results in decreased expression of ELN mRNA |
CTD |
PMID:8997264 |
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NCBI chr12:27,604,983...27,648,413
Ensembl chr12:21,968,544...22,011,928
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G |
Endog |
endonuclease G |
multiple interactions |
ISO |
[Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] affects the localization of ENDOG protein |
CTD |
PMID:17309078 |
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NCBI chr 3:33,846,935...33,849,531
Ensembl chr 3:13,449,086...13,451,932
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G |
Ep300 |
E1A binding protein p300 |
multiple interactions |
ISO |
Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein] |
CTD |
PMID:24632381 |
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NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epas1 |
endothelial PAS domain protein 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:13,543,252...13,626,147
Ensembl chr 6:7,790,647...7,871,228
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G |
Ephb6 |
Eph receptor B6 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of EPHB6 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 4:71,458,632...71,473,889
Ensembl chr 4:70,491,973...70,507,230
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G |
Ephx1 |
epoxide hydrolase 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of EPHX1 protein |
CTD |
PMID:24704207 |
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NCBI chr13:95,246,079...95,275,852
Ensembl chr13:92,714,315...92,790,235
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G |
Erbb2 |
erb-b2 receptor tyrosine kinase 2 |
multiple interactions increases expression |
ISO |
PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein] |
CTD |
PMID:20479004 |
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NCBI chr10:83,907,491...83,931,365
Ensembl chr10:83,411,313...83,435,078
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
increases cleavage multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of ERBB4 protein] |
CTD |
PMID:9685416 |
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NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:69,531,481...70,596,595
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G |
Ereg |
epiregulin |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of EREG protein |
CTD |
PMID:15066986 |
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NCBI chr14:17,311,485...17,325,260
Ensembl chr14:17,027,287...17,041,062
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases expression decreases expression |
ISO |
Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR1 mRNA] [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ESR1 protein; Tetradecanoylphorbol Acetate promotes the reaction [Estradiol results in increased expression of ESR1 protein] Tetradecanoylphorbol Acetate results in decreased expression of ESR1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of ESR1 protein |
CTD |
PMID:9706865 PMID:10633228 PMID:16368122 PMID:19340542 PMID:20559769 |
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NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions increases expression decreases expression |
ISO |
Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ESR2 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA]]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ESR2 mRNA] |
CTD |
PMID:10633228 PMID:20559769 |
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NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
ISO |
[sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of EZH2 protein |
CTD |
PMID:35364107 |
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NCBI chr 4:77,624,223...77,698,598
Ensembl chr 4:76,624,399...76,687,362
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G |
F11r |
F11 receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of F11R mRNA |
CTD |
PMID:23519560 |
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NCBI chr13:86,406,229...86,429,819
Ensembl chr13:83,873,797...83,897,402
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G |
F2 |
coagulation factor II, thrombin |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [F2 protein results in increased uptake of Manganese] |
CTD |
PMID:2125206 |
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NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions increases expression |
ISO |
ochratoxin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of F3 protein Tetradecanoylphorbol Acetate results in increased expression of F3 mRNA; Tetradecanoylphorbol Acetate results in increased expression of F3 protein |
CTD |
PMID:9974427 PMID:18289624 PMID:25569083 |
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NCBI chr 2:212,511,675...212,523,375
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 mRNA; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FABP4 protein |
CTD |
PMID:30218697 PMID:37055963 |
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NCBI chr 2:93,488,251...93,492,961
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FAS mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FAS mRNA] |
CTD |
PMID:21331654 PMID:23519560 |
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NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Testosterone] results in increased expression of FASLG protein; Tamoxifen inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with Estradiol] results in decreased expression of FASLG mRNA] |
CTD |
PMID:20529085 |
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NCBI chr13:76,680,885...76,706,042
Ensembl chr13:74,154,954...74,162,215
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G |
Fau |
FAU ubiquitin like and ribosomal protein S30 fusion |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FAU mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:212,779,429...212,781,028
Ensembl chr 1:203,350,189...203,351,742 Ensembl chr 1:203,350,189...203,351,742 Ensembl chr 6:203,350,189...203,351,742
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G |
Fbln7 |
fibulin 7 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FBLN7 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983
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G |
Fen1 |
flap structure-specific endonuclease 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FEN1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:216,270,016...216,274,873
Ensembl chr 1:206,844,884...206,850,003
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G |
Fga |
fibrinogen alpha chain |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FGA mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:170,672,169...170,679,572
Ensembl chr 2:168,374,120...168,381,528
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G |
Fgb |
fibrinogen beta chain |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FGB mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:170,693,966...170,700,875
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf1 |
fibroblast growth factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr18:30,937,670...31,023,786
Ensembl chr18:30,686,581...30,772,357
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G |
Fgf10 |
fibroblast growth factor 10 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF10 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866
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G |
Fgf16 |
fibroblast growth factor 16 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FGF16 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:74,882,863...74,893,598
Ensembl chr X:70,817,433...70,878,717
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G |
Fgf18 |
fibroblast growth factor 18 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FGF18 mRNA |
CTD |
PMID:23519560 |
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NCBI chr10:18,210,240...18,241,929
Ensembl chr10:17,706,174...17,736,818
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions increases secretion |
EXP ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGF2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [EGR1 protein binds to FGF2 promoter] Tetradecanoylphorbol Acetate results in increased secretion of FGF2 protein |
CTD |
PMID:10779383 PMID:11874475 PMID:15654655 |
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NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf7 |
fibroblast growth factor 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGF7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:133,734,557...133,786,678
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgfr2 |
fibroblast growth factor receptor 2 |
multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of FGFR2 protein] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FGFR2 mRNA |
CTD |
PMID:15654655 PMID:23519560 |
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NCBI chr 1:194,175,703...194,280,914
Ensembl chr 1:184,745,420...184,850,626
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G |
Fgg |
fibrinogen gamma chain |
increases expression |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of FGG mRNA |
CTD |
PMID:2440878 |
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NCBI chr 2:170,652,929...170,660,372
Ensembl chr 2:168,355,013...168,362,322
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G |
Fkbp5 |
FKBP prolyl isomerase 5 |
multiple interactions increases expression |
ISO |
BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FKBP5 mRNA] |
CTD |
PMID:20858459 |
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NCBI chr20:6,458,931...6,577,227
Ensembl chr20:6,457,216...6,541,674
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
multiple interactions increases expression increases secretion |
ISO |
ATP7A protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FLT1 mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FLT1 protein] |
CTD |
PMID:19205902 PMID:22197494 |
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NCBI chr12:12,333,050...12,504,750
Ensembl chr12:7,297,292...7,468,626
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G |
Flt3 |
Fms related receptor tyrosine kinase 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of FLT3 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr12:12,660,035...12,735,584
Ensembl chr12:7,623,930...7,699,474
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G |
Fmo5 |
flavin containing dimethylaniline monoxygenase 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FMO5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:187,885,741...187,938,468
Ensembl chr 2:185,222,204...185,249,693
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G |
Fn1 |
fibronectin 1 |
multiple interactions increases expression increases secretion |
ISO |
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FN1 mRNA; Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FN1 mRNA]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of FN1 protein] |
CTD |
PMID:15086456 PMID:16979875 PMID:24211529 |
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NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression increases activity affects localization |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOS mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of FOS protein; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of FOS protein] Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOS protein Tetradecanoylphorbol Acetate results in increased activity of FOS protein 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of FOS mRNA] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOS mRNA; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of FOS protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of FOS mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of FOS protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] |
CTD |
PMID:1932749 PMID:7564102 PMID:7963561 PMID:8386370 PMID:8631129 PMID:9067545 PMID:9122163 PMID:9242432 PMID:9270009 PMID:9417049 PMID:9580328 PMID:9650640 PMID:10381133 PMID:10484327 PMID:10620351 PMID:10693946 PMID:10739673 PMID:10910055 PMID:11113530 PMID:11687581 PMID:12782152 PMID:15477007 PMID:15705907 PMID:16116958 PMID:17114644 PMID:17360982 PMID:17693661 PMID:18551458 PMID:18755854 PMID:19225867 PMID:19282384 PMID:19375915 PMID:19716839 PMID:19945525 PMID:20152819 PMID:20590612 PMID:20599481 PMID:21047949 PMID:21354279 PMID:22561169 PMID:22634262 PMID:25656647 PMID:30133131 PMID:30590137 PMID:30696844 PMID:31068361 PMID:31904401 More...
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NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased expression of FOSB mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSB protein [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FOSB mRNA |
CTD |
PMID:11113530 PMID:17148446 PMID:31068361 PMID:31904401 |
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NCBI chr 1:88,082,324...88,089,506
Ensembl chr 1:78,954,115...78,961,465
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO EXP |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FOSL1 mRNA; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein] Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein] Tetradecanoylphorbol Acetate results in increased expression of FOSL1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of FOSL1 protein |
CTD |
PMID:9122163 PMID:11113530 PMID:17148446 PMID:18755854 PMID:19000923 |
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NCBI chr 1:212,183,885...212,192,391
Ensembl chr 1:202,754,529...202,764,930
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of FOSL2 mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOSL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] |
CTD |
PMID:15477007 PMID:16979875 PMID:17148446 |
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NCBI chr 6:30,017,952...30,039,269
Ensembl chr 6:24,300,956...24,320,034
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G |
Foxo3 |
forkhead box O3 |
multiple interactions increases activity decreases phosphorylation |
ISO |
FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2] Tetradecanoylphorbol Acetate results in increased activity of FOXO3 protein Tetradecanoylphorbol Acetate results in decreased phosphorylation of FOXO3 protein |
CTD |
PMID:21705328 |
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NCBI chr20:47,251,968...47,348,254
Ensembl chr20:45,672,995...45,764,561
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G |
Foxp3 |
forkhead box P3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FOXP3 protein |
CTD |
PMID:27865421 |
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NCBI chr X:17,580,380...17,601,181
Ensembl chr X:14,908,494...14,923,838
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G |
Frmd3 |
FERM domain containing 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FRMD3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:92,810,989...93,077,326
Ensembl chr 5:87,764,604...88,031,091
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G |
Fscn1 |
fascin actin-bundling protein 1 |
multiple interactions increases expression |
ISO |
FSCN1 mutant form affects the expression of [Tetradecanoylphorbol Acetate results in increased expression of TNF protein] Tetradecanoylphorbol Acetate results in increased expression of FSCN1 mRNA |
CTD |
PMID:22102721 |
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NCBI chr12:16,710,601...16,723,734
Ensembl chr12:11,597,048...11,610,211
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G |
Fshb |
follicle stimulating hormone subunit beta |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of FSHB mRNA |
CTD |
PMID:21467749 |
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NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370
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G |
Fstl1 |
follistatin-like 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of FSTL1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:76,400,870...76,454,053
Ensembl chr11:62,779,783...62,948,677
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G |
Fstl4 |
follistatin-like 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FSTL4 mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:37,412,288...37,845,405
Ensembl chr10:36,911,420...37,338,588
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G |
Fut4 |
fucosyltransferase 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of FUT4 protein |
CTD |
PMID:26036281 |
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NCBI chr 8:19,868,178...19,872,139
Ensembl chr 8:11,586,721...11,590,682
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G |
Fxyd6 |
FXYD domain-containing ion transport regulator 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of FXYD6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:54,575,578...54,602,715
Ensembl chr 8:45,678,885...45,705,958
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G |
Fyb1 |
FYN binding protein 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:57,360,084...57,508,609
Ensembl chr 2:55,632,698...55,779,629
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G |
Fyn |
FYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of FYN mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:44,322,635...44,514,498
Ensembl chr20:42,766,369...42,959,911
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions decreases expression |
ISO |
geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of G6PD protein] |
CTD |
PMID:23399806 |
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NCBI chr X:157,352,364...157,372,144
Ensembl chr X:152,201,098...152,220,801
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G |
Gabra3 |
gamma-aminobutyric acid type A receptor subunit alpha 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GABRA3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr X:155,301,979...155,543,870
Ensembl chr X:150,261,607...150,501,559
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of GABRA4 mRNA Tetradecanoylphorbol Acetate promotes the reaction [EGR3 protein binds to GABRA4 promoter] |
CTD |
PMID:16091474 |
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NCBI chr14:36,944,747...37,021,652
Ensembl chr14:36,590,782...36,665,844
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GADD45A mRNA |
CTD |
PMID:10910055 |
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NCBI chr 4:97,484,497...97,486,799
Ensembl chr 4:96,154,789...96,157,115
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G |
Gas6 |
growth arrest specific 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GAS6 mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:82,747,676...82,778,090
Ensembl chr16:76,045,426...76,075,904
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G |
Gast |
gastrin |
increases secretion |
EXP |
Tetradecanoylphorbol Acetate results in increased secretion of GAST protein |
CTD |
PMID:19208342 |
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NCBI chr10:85,765,216...85,767,881
Ensembl chr10:85,264,832...85,267,496
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions increases activity |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter] Tetradecanoylphorbol Acetate results in increased activity of GATA1 protein |
CTD |
PMID:14623254 |
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NCBI chr X:17,193,291...17,209,462
Ensembl chr X:14,529,702...14,537,530
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G |
Gata2 |
GATA binding protein 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA tellimagrandin I promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GATA2 mRNA] |
CTD |
PMID:14757314 |
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NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:120,658,986...120,667,761
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G |
Gata3 |
GATA binding protein 3 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA |
CTD |
PMID:22398747 |
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NCBI chr17:73,544,234...73,575,670
Ensembl chr17:68,643,873...68,665,391
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G |
Gata4 |
GATA binding protein 4 |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GATA4 protein |
CTD |
PMID:11583584 |
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NCBI chr15:41,635,572...41,707,252
Ensembl chr15:37,459,601...37,505,636
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G |
Gatd1 |
glutamine amidotransferase class 1 domain containing 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of GATD1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:205,936,189...205,942,121
Ensembl chr 1:196,504,833...196,512,551
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G |
Gba1 |
glucosylceramidase beta 1 |
multiple interactions |
ISO |
GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] |
CTD |
PMID:24951586 |
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NCBI chr 2:176,902,141...176,916,015
Ensembl chr 2:174,609,403...174,618,263
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G |
Gbp3 |
guanylate binding protein 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of GBP3 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 2:234,144,042...234,173,527
Ensembl chr 2:231,486,062...231,493,098
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Rosuvastatin Calcium] results in increased expression of GCLC mRNA Tetradecanoylphorbol Acetate results in increased expression of GCLC mRNA |
CTD |
PMID:17200146 PMID:18154958 PMID:26198647 |
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NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA]; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of GCLM mRNA] |
CTD |
PMID:24632381 |
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NCBI chr 2:213,032,135...213,052,192
Ensembl chr 2:210,347,482...210,367,535
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G |
Gcnt3 |
glucosaminyl (N-acetyl) transferase 3, mucin type |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GCNT3 mRNA |
CTD |
PMID:26198647 |
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NCBI chr 8:79,570,081...79,577,389
Ensembl chr 8:70,686,844...70,699,562
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G |
Gdf10 |
growth differentiation factor 10 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GDF10 mRNA |
CTD |
PMID:16979875 |
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NCBI chr16:9,243,434...9,256,788
Ensembl chr16:9,237,261...9,249,343
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G |
Gdf11 |
growth differentiation factor 11 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF11 mRNA] |
CTD |
PMID:32135139 |
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NCBI chr 7:1,896,229...1,909,147
Ensembl chr 7:1,311,732...1,320,725
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G |
Gdf15 |
growth differentiation factor 15 |
multiple interactions increases expression |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GDF15 protein; [SB 203580 co-treated with 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GDF15 protein] |
CTD |
PMID:23996089 PMID:30218697 |
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NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055
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G |
Gfi1 |
growth factor independent 1 transcriptional repressor |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of GFI1 mRNA |
CTD |
PMID:16888099 |
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NCBI chr14:2,185,489...2,204,191
Ensembl chr14:2,042,434...2,051,814
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G |
Gfra2 |
GDNF family receptor alpha 2 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr15:52,351,499...52,443,369
Ensembl chr15:45,941,828...46,033,714
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G |
Gja1 |
gap junction protein, alpha 1 |
multiple interactions decreases expression decreases localization increases phosphorylation affects localization increases expression |
ISO EXP |
Ethinyl Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein] Tetradecanoylphorbol Acetate results in decreased expression of GJA1 protein Tetradecanoylphorbol Acetate results in decreased localization of GJA1 protein Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein Tetradecanoylphorbol Acetate results in decreased expression of GJA1 mRNA Tetradecanoylphorbol Acetate affects the localization of GJA1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of GJA1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in decreased activity of GJA1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of GJA1 protein Tetradecanoylphorbol Acetate results in increased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein; Tetradecanoylphorbol Acetate results in increased expression of GJA1 protein modified form [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJA1 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJA1 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJA1 mRNA; Tetradecanoylphorbol Acetate affects the reaction [GJA1 protein results in increased susceptibility to Etoposide] |
CTD |
PMID:7586169 PMID:7586191 PMID:8020150 PMID:8068183 PMID:8285856 PMID:8597533 PMID:9797139 PMID:10633228 PMID:10973802 PMID:11532878 PMID:11711124 PMID:15250540 PMID:15685554 PMID:19840844 PMID:20510257 PMID:23978459 PMID:30668803 PMID:35413382 PMID:36925031 More...
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NCBI chr20:36,302,490...36,315,010
Ensembl chr20:35,755,991...35,768,582
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G |
Gjb2 |
gap junction protein, beta 2 |
multiple interactions decreases expression increases expression |
ISO EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of GJB2 protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GJB2 mRNA Tetradecanoylphorbol Acetate results in decreased expression of GJB2 protein Tetradecanoylphorbol Acetate results in increased expression of GJB2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of GJB2 protein |
CTD |
PMID:7586191 PMID:8068183 PMID:8597533 |
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NCBI chr15:35,375,977...35,393,817
Ensembl chr15:31,260,357...31,278,177
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G |
Gjb5 |
gap junction protein, beta 5 |
multiple interactions decreases expression |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GJB5 mRNA Tetradecanoylphorbol Acetate results in decreased expression of GJB5 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GJB5 protein |
CTD |
PMID:7586191 PMID:8597533 |
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NCBI chr 5:144,965,133...144,968,051
Ensembl chr 5:139,680,671...139,683,583
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G |
Glra1 |
glycine receptor, alpha 1 |
decreases activity |
EXP |
Tetradecanoylphorbol Acetate results in decreased activity of GLRA1 protein |
CTD |
PMID:7752562 |
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NCBI chr10:40,128,284...40,228,612
Ensembl chr10:39,629,459...39,727,162
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G |
Gnrhr |
gonadotropin releasing hormone receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of GNRHR mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:22,211,666...22,229,654
Ensembl chr14:21,856,871...21,874,861
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G |
Gp1ba |
glycoprotein Ib platelet subunit alpha |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GP1BA protein] |
CTD |
PMID:20523355 |
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NCBI chr10:55,831,901...55,856,729
Ensembl chr10:55,352,899...55,356,774
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPAT3 mRNA |
CTD |
PMID:26198647 |
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NCBI chr14:9,018,762...9,072,552
Ensembl chr14:8,714,373...8,766,490
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G |
Gpc4 |
glypican 4 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GPC4 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:136,565,536...136,676,142
Ensembl chr X:131,644,704...131,755,284
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] |
CTD |
PMID:2523799 |
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NCBI chr 7:132,722,982...132,730,373
Ensembl chr 7:130,844,138...130,851,529
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G |
Gpr3 |
G protein-coupled receptor 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPR3 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 5:150,695,406...150,698,526
Ensembl chr 5:145,411,510...145,414,590
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G |
Gpr84 |
G protein-coupled receptor 84 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPR84 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
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G |
Gpx1 |
glutathione peroxidase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GPX1 protein |
CTD |
PMID:10432307 |
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NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx4 |
glutathione peroxidase 4 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of GPX4 protein Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of GPX4 protein] |
CTD |
PMID:10432307 PMID:35608139 |
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NCBI chr 7:10,300,833...10,303,629
Ensembl chr 7:9,650,185...9,652,982
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G |
Gria3 |
glutamate ionotropic receptor AMPA type subunit 3 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIA3 mRNA |
CTD |
PMID:23519560 |
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NCBI chr X:125,103,975...125,369,690
Ensembl chr X:120,238,534...120,504,096
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G |
Grik5 |
glutamate ionotropic receptor kainate type subunit 5 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GRIK5 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:89,733,736...89,795,769
Ensembl chr 1:80,605,892...80,667,125
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G |
Grn |
granulin precursor |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GRN mRNA |
CTD |
PMID:16873554 |
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NCBI chr10:87,887,834...87,893,938
Ensembl chr10:87,387,638...87,393,775
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G |
Grp |
gastrin releasing peptide |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [GRP protein modified form results in increased chemical synthesis of Inositol Phosphates] |
CTD |
PMID:18313772 |
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NCBI chr18:61,658,655...61,672,037
Ensembl chr18:59,388,274...59,402,061
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G |
Grpr |
gastrin releasing peptide receptor |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GRPR protein |
CTD |
PMID:29669290 |
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NCBI chr X:34,630,238...34,670,245
Ensembl chr X:30,998,416...31,038,442
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G |
Gsk3a |
glycogen synthase kinase 3 alpha |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3A protein] |
CTD |
PMID:17993264 |
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NCBI chr 1:89,943,669...89,953,514
Ensembl chr 1:80,815,850...80,825,802
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:17993264 |
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NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions increases activity decreases activity decreases expression |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of GSR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of GSR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of GSR protein; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of GSR protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of GSR protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GSR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [GSR protein results in increased oxidation of NADP] |
CTD |
PMID:11243714 PMID:12504893 PMID:14997284 PMID:19161993 PMID:20691676 PMID:22036979 PMID:22760862 PMID:23399806 More...
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NCBI chr16:65,185,574...65,228,742
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [1,2-dithiol-3-thione results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [2-tert-butylhydroquinone results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benzylideneacetone results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Dimercaprol results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Mercuric Chloride results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [sodium arsenite results in increased expression of GSTA1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [sulforaphane results in increased expression of GSTA1 mRNA] |
CTD |
PMID:7568053 |
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NCBI chr 8:87,985,768...87,997,766
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstm2 |
glutathione S-transferase mu 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of GSTM2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 2:198,312,179...198,316,962
Ensembl chr 2:195,544,426...195,628,961
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G |
Gsto1 |
glutathione S-transferase omega 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTO1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:256,662,377...256,672,515
Ensembl chr 1:246,721,221...246,731,468
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions increases expression decreases expression |
ISO |
beta-lapachone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Emodin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; sanguinarine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GSTP1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [GATA1 protein binds to GSTP1 promoter] [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTP1 mRNA Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of GSTP1 protein |
CTD |
PMID:14623254 PMID:15313406 PMID:15533597 PMID:19840844 |
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NCBI chr 1:210,767,237...210,770,242
Ensembl chr 1:201,321,672...201,340,226
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G |
Gstt1 |
glutathione S-transferase theta 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of GSTT1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr20:12,856,068...12,873,020
Ensembl chr20:12,856,669...12,873,585
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G |
Gtf2h4 |
general transcription factor 2H subunit 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of GTF2H4 mRNA |
CTD |
PMID:19031421 |
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NCBI chr20:3,076,110...3,081,805
Ensembl chr20:3,071,328...3,076,984
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G |
Gypa |
glycophorin A |
multiple interactions decreases expression increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; chebulinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of GYPA protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein] |
CTD |
PMID:14769215 PMID:20523355 |
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NCBI chr19:44,354,669...44,370,304
Ensembl chr19:27,450,308...27,465,822
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G |
Gzmb |
granzyme B |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GZMB protein Tetradecanoylphorbol Acetate results in increased expression of GZMB mRNA |
CTD |
PMID:20883105 PMID:30171972 |
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NCBI chr15:34,459,007...34,462,469
Ensembl chr15:30,173,603...30,346,814
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA |
CTD |
PMID:15477007 |
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NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869
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G |
Hal |
histidine ammonia lyase |
multiple interactions |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of HAL protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of HAL protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of HAL protein |
CTD |
PMID:20691676 |
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NCBI chr 7:29,894,495...29,924,744
Ensembl chr 7:28,006,972...28,037,701
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G |
Hars1 |
histidyl-tRNA synthetase 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr18:28,655,669...28,672,712
Ensembl chr18:28,381,655...28,398,740
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions increases secretion increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of HBEGF mRNA Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein Tetradecanoylphorbol Acetate results in increased expression of HBEGF mRNA [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of HBEGF mRNA; ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein]; RHBDF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein] |
CTD |
PMID:10910055 PMID:16979875 PMID:20660715 PMID:28703301 |
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NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,105,760...28,116,441
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G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HCK mRNA |
CTD |
PMID:15477007 PMID:23519560 |
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NCBI chr 3:162,031,833...162,074,933
Ensembl chr 3:141,571,587...141,614,693
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G |
Hdac5 |
histone deacetylase 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein; Go 6976 inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein] [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased expression of HDAC5 protein]] |
CTD |
PMID:19124542 PMID:36075570 |
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NCBI chr10:87,653,139...87,688,078
Ensembl chr10:87,152,978...87,188,235
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G |
Hdac9 |
histone deacetylase 9 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HDAC9 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 6:56,489,472...57,351,654
Ensembl chr 6:50,763,590...51,625,333
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G |
Hdc |
histidine decarboxylase |
increases activity multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of HDC protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein; atractylon inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein]; pyeongwee-san extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased activity of HDC protein] |
CTD |
PMID:10428506 PMID:27553716 |
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NCBI chr 3:134,300,628...134,318,704
Ensembl chr 3:113,847,260...113,865,341
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G |
Hebp2 |
heme binding protein 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HEBP2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:15,014,729...15,021,523
Ensembl chr 1:13,194,982...13,201,777
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G |
Hells |
helicase, lymphoid specific |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HELLS mRNA |
CTD |
PMID:19000923 |
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NCBI chr 1:246,113,580...246,159,230
Ensembl chr 1:236,701,758...236,746,844
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G |
Hgf |
hepatocyte growth factor |
multiple interactions increases expression |
ISO |
Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA]; Ursodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HGF mRNA Tetradecanoylphorbol Acetate results in increased expression of HGF mRNA; Tetradecanoylphorbol Acetate results in increased expression of HGF protein |
CTD |
PMID:15802798 PMID:23519560 |
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NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:18,677,101...18,745,409
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G |
Hhip |
Hedgehog-interacting protein |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HHIP mRNA |
CTD |
PMID:23519560 |
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NCBI chr19:44,768,038...44,856,878
Ensembl chr19:27,863,213...27,952,528
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Dithiothreitol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA] Tetradecanoylphorbol Acetate results in increased expression of HIF1A mRNA alternative form; Tetradecanoylphorbol Acetate results in increased expression of HIF1A protein alternative form |
CTD |
PMID:11424089 PMID:12479793 PMID:14695184 |
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NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr12:11,009,236...11,015,941
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HMGCR mRNA |
CTD |
PMID:12044893 |
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NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of HMGCS1 mRNA |
CTD |
PMID:12044893 |
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NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HMOX1 mRNA; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; HMOX1 protein affects the reaction [Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]] HMOX1 enhancer affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of HMOX1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA] |
CTD |
PMID:7538129 PMID:18078826 PMID:18958680 PMID:23288142 PMID:24632381 |
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NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
multiple interactions increases expression |
ISO |
Indomethacin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of HPGD mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of and results in increased activity of HPGD protein] |
CTD |
PMID:11237475 PMID:15680906 |
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NCBI chr16:38,996,876...39,034,831
Ensembl chr16:33,986,266...34,024,228
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HPRT1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:137,655,744...137,687,718
Ensembl chr X:132,736,096...132,768,154
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of HRAS mRNA; HRAS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CDH5 protein] Tetradecanoylphorbol Acetate results in increased expression of HRAS mRNA [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate co-treated with mezerein] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HRAS mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; [Benzo(a)pyrene co-treated with Tetradecanoylphorbol Acetate] affects the mutagenesis of HRAS gene; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with geraniol] affects the localization of HRAS protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of HRAS protein; [Zidovudine co-treated with Tetradecanoylphorbol Acetate] results in increased mutagenesis of HRAS gene; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRAS mRNA] |
CTD |
PMID:3115617 PMID:9766437 PMID:11241758 PMID:11765016 PMID:17106253 PMID:18922899 PMID:22760862 PMID:24211779 More...
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NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:196,296,263...196,300,615
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G |
Hrh1 |
histamine receptor H 1 |
multiple interactions increases expression |
ISO |
Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HRH1 mRNA] |
CTD |
PMID:23333628 |
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NCBI chr 4:149,120,511...149,204,267
Ensembl chr 4:147,645,995...147,647,455
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G |
Hrh2 |
histamine receptor H 2 |
multiple interactions |
ISO |
HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]] |
CTD |
PMID:19277450 |
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NCBI chr17:10,371,083...10,412,979
Ensembl chr17:10,368,298...10,407,631
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G |
Hs6st2 |
heparan sulfate 6-O-sulfotransferase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HS6ST2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr X:135,887,224...136,182,388
Ensembl chr X:130,968,385...131,261,492
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G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
increases activity increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased activity of HSD11B1 protein Tetradecanoylphorbol Acetate results in increased expression of HSD11B1 mRNA |
CTD |
PMID:16533503 |
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NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687
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G |
Hspa1a |
heat shock protein family A (Hsp70) member 1A |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA1A mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:3,875,411...3,877,866
Ensembl chr20:3,856,006...3,873,227
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G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
multiple interactions |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of HSPA2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA2 mRNA |
CTD |
PMID:18958680 |
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NCBI chr 6:100,864,172...100,866,946
Ensembl chr 6:95,128,350...95,131,287
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 protein] |
CTD |
PMID:10652249 |
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NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa6l-ps1 |
heat shock protein family A (Hsp70) member 6 like, pseudogene 1 |
multiple interactions |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in increased expression of HSPA6 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA6 mRNA |
CTD |
PMID:18958680 PMID:24849683 |
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NCBI chr13:85,805,911...85,807,052
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:50,080,514...50,084,376
Ensembl chr 8:41,183,264...41,187,259
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of HSPA9 mRNA |
CTD |
PMID:18958680 |
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NCBI chr18:26,810,004...26,832,958
Ensembl chr18:26,535,798...26,554,292
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions increases phosphorylation increases expression |
EXP ISO |
Pentobarbital inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HSPB1 protein] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HSPB1 mRNA Tetradecanoylphorbol Acetate results in increased phosphorylation of HSPB1 protein |
CTD |
PMID:7541446 PMID:10839933 PMID:31904401 |
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NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743
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G |
Hyi |
hydroxypyruvate isomerase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of HYI mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:137,179,975...137,182,654
Ensembl chr 5:131,894,598...131,897,251
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G |
Ibsp |
integrin-binding sialoprotein |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IBSP mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:5,744,497...5,757,242
Ensembl chr14:5,439,829...5,452,693
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
ISO |
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]]; 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ICAM1 protein; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Buthionine Sulfoximine results in increased expression of ICAM1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein] Tetradecanoylphorbol Acetate results in increased expression of ICAM1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of ICAM1 protein |
CTD |
PMID:10484327 PMID:11164475 PMID:20920494 PMID:30218697 PMID:31351099 |
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NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438
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G |
Ier2 |
immediate early response 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IER2 mRNA |
CTD |
PMID:31068361 |
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NCBI chr19:40,399,373...40,400,897
Ensembl chr19:23,494,184...23,499,211
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G |
Ier3 |
immediate early response 3 |
multiple interactions increases expression |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IER3 mRNA Tetradecanoylphorbol Acetate results in increased expression of IER3 mRNA |
CTD |
PMID:19840844 PMID:19945525 PMID:31068361 |
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NCBI chr20:2,933,173...2,934,377
Ensembl chr20:2,928,378...2,929,583
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G |
Ifi27l2a |
interferon, alpha-inducible protein 27 like 2A |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI27L2A mRNA |
CTD |
PMID:31904401 |
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NCBI chr 6:128,363,658...128,365,144
Ensembl chr 6:122,598,872...122,600,360
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G |
Ifi44 |
interferon-induced protein 44 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IFI44 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:243,286,050...243,303,869
Ensembl chr 2:240,626,066...240,643,844
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G |
Ifng |
interferon gamma |
multiple interactions increases expression increases secretion |
ISO EXP |
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [2,4-diaminotoluene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Azathioprine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclophosphamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IFNG protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IFNG promoter]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IFNG protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IFNG protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [IFNG protein promotes the reaction [Decitabine results in increased expression of PLA2G2A protein]]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA] Tetradecanoylphorbol Acetate results in increased expression of IFNG protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA] 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein; [Mercuric Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IFNG protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; Estradiol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; Resveratrol affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IFNG protein]; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] |
CTD |
PMID:1371491 PMID:12411406 PMID:12755381 PMID:12812920 PMID:14623498 PMID:14994387 PMID:15358692 PMID:15379866 PMID:15588918 PMID:16154495 PMID:16374615 PMID:16716911 PMID:17051331 PMID:17475810 PMID:17572062 PMID:17685462 PMID:18541274 PMID:18953428 PMID:19277450 PMID:21569788 PMID:22077062 PMID:22398747 PMID:24603311 PMID:25073960 PMID:25114106 PMID:26343699 PMID:29594315 PMID:30171972 PMID:31351099 More...
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NCBI chr 7:55,789,180...55,793,216
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:44,265,703...44,283,975
Ensembl chr11:30,779,733...30,798,005
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IGF1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IGF1 mRNA; IGF1 protein results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:10365914 PMID:16368122 PMID:31904401 |
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NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions increases phosphorylation |
ISO |
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IGF1R protein] |
CTD |
PMID:26513295 |
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NCBI chr 1:130,959,787...131,248,664
Ensembl chr 1:121,550,743...121,831,777
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP1 mRNA |
CTD |
PMID:16368122 |
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NCBI chr14:86,261,277...86,266,344
Ensembl chr14:82,047,415...82,052,482
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions increases expression |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IGFBP3 mRNA Tetradecanoylphorbol Acetate results in increased expression of IGFBP3 mRNA |
CTD |
PMID:16368122 PMID:19945525 |
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NCBI chr14:86,270,208...86,277,944
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP5 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 9:81,901,605...81,914,187
Ensembl chr 9:74,448,382...74,465,156
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IGFBP7 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:31,091,681...31,151,623
Ensembl chr14:30,737,164...30,797,314
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions increases phosphorylation increases activity |
ISO |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]; Dithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IKBKB protein]]; Estradiol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; Fulvestrant promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of IKBKB protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of IKBKB protein |
CTD |
PMID:16474181 PMID:20584749 PMID:23899529 PMID:26220752 |
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NCBI chr16:76,021,968...76,075,717
Ensembl chr16:69,319,554...69,373,250
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein; capsiate analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased activity of IKBKG protein] Tetradecanoylphorbol Acetate results in increased expression of IKBKG protein decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IKBKG protein] |
CTD |
PMID:12115659 PMID:31351099 |
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NCBI chr X:157,358,279...157,397,563
Ensembl chr X:152,216,596...152,239,499
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G |
Il10 |
interleukin 10 |
multiple interactions increases expression increases secretion decreases expression |
ISO EXP |
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; catechol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 protein]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; hydroxyhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL10 protein]; quinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL10 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL10 protein] [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein]; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [Silicon Dioxide co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased secretion of IL10 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA]]; Genistein affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL10 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL10 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of IL10 mRNA |
CTD |
PMID:12884291 PMID:15502056 PMID:15588918 PMID:15614042 PMID:16374615 PMID:16716911 PMID:17051331 PMID:17572062 PMID:17685462 PMID:19277450 PMID:20423157 PMID:22398747 PMID:25114106 PMID:25128825 PMID:27865421 PMID:29777833 PMID:38380914 More...
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NCBI chr13:45,024,921...45,029,586
Ensembl chr13:42,472,839...42,477,313
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G |
Il11 |
interleukin 11 |
multiple interactions increases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL11 mRNA] |
CTD |
PMID:22138297 |
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NCBI chr 1:78,098,622...78,104,915
Ensembl chr 1:69,068,137...69,076,129
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G |
Il12a |
interleukin 12A |
multiple interactions |
ISO |
IL12A results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:22359662 |
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NCBI chr 2:155,275,734...155,282,997
Ensembl chr 2:152,965,769...152,972,734
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G |
Il12b |
interleukin 12B |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12B mRNA Tetradecanoylphorbol Acetate inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL12B protein] |
CTD |
PMID:15614042 PMID:36416909 |
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NCBI chr10:29,390,300...29,405,194
Ensembl chr10:28,893,008...28,902,903
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G |
Il12rb1 |
interleukin 12 receptor subunit beta 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12RB1 protein [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL12RB1 mRNA] |
CTD |
PMID:11441113 PMID:21331654 |
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NCBI chr16:18,654,207...18,668,887
Ensembl chr16:18,620,770...18,632,769
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G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL12RB2 protein [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL12RB2 mRNA |
CTD |
PMID:11441113 PMID:16979875 |
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NCBI chr 4:97,756,089...97,844,937
Ensembl chr 4:96,426,842...96,515,289
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G |
Il13 |
interleukin 13 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL13 mRNA [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13 mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]] 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL13 mRNA] |
CTD |
PMID:10428506 PMID:21331654 PMID:22398747 PMID:25114106 PMID:26091108 |
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NCBI chr10:38,290,926...38,293,483
Ensembl chr10:37,790,130...37,792,737
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL13RA1 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr X:120,213,670...120,294,777
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO |
1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-(1,1'-biphenyl)-4-yl)propan-2-ol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; 1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-(1,1'-biphenyl)-4-yl)propan-2-ol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL17A protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A protein; biochanin A promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; daidzein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Digoxin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Digoxin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A protein]; enilconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; formononetin promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; Genistein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; hexaconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL17A mRNA]; T0901317 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; tetraconazole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; triflumizol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL17A mRNA]; yakuchinone-A inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of and results in increased secretion of IL17A protein] [Trinitrobenzenesulfonic Acid results in increased susceptibility to [Ionomycin co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of IL17A protein |
CTD |
PMID:22289359 PMID:22292739 PMID:25583575 PMID:26513295 PMID:27783946 PMID:31001353 More...
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NCBI chr 9:30,640,844...30,644,331
Ensembl chr 9:23,144,402...23,147,889
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G |
Il17ra |
interleukin 17 receptor A |
multiple interactions decreases response to substance |
ISO |
[IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of TNF protein; IL17RA gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL10 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL16 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of CXCL9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL1 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein]; IL17RA results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] |
CTD |
PMID:22359662 |
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NCBI chr 4:155,339,742...155,362,382
Ensembl chr 4:153,667,534...153,690,174
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G |
Il18r1 |
interleukin 18 receptor 1 |
multiple interactions |
ISO |
[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL18R1 protein |
CTD |
PMID:14994387 |
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NCBI chr 9:50,223,274...50,257,370
Ensembl chr 9:42,727,869...42,760,715
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
ISO |
5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; [sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein; Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A protein]; diacerein inhibits the reaction [[sodium arsenite co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1A protein [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1A mRNA; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA] |
CTD |
PMID:7665919 PMID:8435107 PMID:8702551 PMID:9122163 PMID:11851881 PMID:21045076 PMID:35364107 More...
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NCBI chr 3:136,979,804...136,990,236
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression increases secretion |
ISO EXP |
[[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased cleavage of CASP1 protein] which results in increased secretion of IL1B protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of IL1B protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1B mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; [Nigericin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Poly dA-dT] results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL1B protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL1B protein; [Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; bafilomycin A1 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL1B mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Cytochalasin D inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL1B protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; IL13 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; MitoTEMPO inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL1B protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL1B protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; Sodium inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein; Triclosan inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with TNF protein] results in increased expression of IL1B protein]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with nickel chloride] results in increased secretion of IL1B protein]; Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL1B protein] Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein] Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL1B protein [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of IL1B protein; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone] |
CTD |
PMID:9122163 PMID:9584910 PMID:10072544 PMID:12812920 PMID:14623498 PMID:16374615 PMID:16557482 PMID:17071120 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18958421 PMID:20423157 PMID:20709134 PMID:21035309 PMID:21515303 PMID:21807015 PMID:22322153 PMID:22359662 PMID:22981962 PMID:23253724 PMID:23399806 PMID:23430110 PMID:23535185 PMID:23680697 PMID:24131540 PMID:24158569 PMID:24964617 PMID:25446327 PMID:25818598 PMID:26091108 PMID:29458014 PMID:29508652 PMID:30254419 PMID:31351099 More...
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NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r1 |
interleukin 1 receptor type 1 |
multiple interactions increases expression |
ISO |
SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA] |
CTD |
PMID:21045076 |
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NCBI chr 9:50,000,558...50,076,579
Ensembl chr 9:42,504,735...42,579,937
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G |
Il1r2 |
interleukin 1 receptor type 2 |
multiple interactions increases expression |
ISO |
SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA] |
CTD |
PMID:21045076 |
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NCBI chr 9:49,879,928...49,920,374
Ensembl chr 9:42,384,433...42,424,725
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G |
Il1rap |
interleukin 1 receptor accessory protein |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAP mRNA |
CTD |
PMID:16979875 |
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NCBI chr11:87,567,813...87,704,346
Ensembl chr11:74,070,304...74,199,530
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G |
Il1rapl2 |
interleukin 1 receptor accessory protein-like 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL1RAPL2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:105,547,403...107,080,369
Ensembl chr X:100,961,812...102,271,753
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of IL1RL1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 9:50,157,326...50,222,888
Ensembl chr 9:42,697,192...42,727,256
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions increases expression |
ISO |
NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1RN protein] |
CTD |
PMID:10072544 |
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NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445
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G |
Il2 |
interleukin 2 |
increases secretion multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; 4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [2-anthramine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [4-nitroaniline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Acetaminophen co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Aluminum Chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Amphotericin B co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Benzethonium co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chloroquine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Cisplatin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [citral co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [cobaltous chloride co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Colchicine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dexamethasone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [dibenzo(a,i)pyrene co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dibutyl Phthalate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [diethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Digoxin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Dimethyl Sulfoxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Formaldehyde co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [FR 167653 co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Histamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrocortisone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Hydrogen Peroxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Isoniazid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [isophorone diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [lead acetate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Lithium Carbonate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Methotrexate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Minocycline co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mitomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Niacinamide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [nickel sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Nitrofurazone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Pyrimethamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Ribavirin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [sodium bromate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Sulfasalazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tacrolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [triethanolamine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Vehicle Emissions co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; [Warfarin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Alitretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Go 6976 inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNA2 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNE1 protein]; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; Lenalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; monocyte locomotion inhibitory factor promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; nickel chloride inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 promoter]; norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Pyrazoles analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; rottlerin inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; SB 203580 inhibits the reaction [norcantharidin inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of IL2 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL2 protein]; T 0070907 inhibits the reaction [ciglitazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]]; T 0070907 promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL2 protein]; Tacrolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Zinc deficiency affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; Zinc Sulfate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL2 protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA] 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein; [Benzocaine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [bis(tri-n-butyltin)oxide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 protein; [Sodium Dodecyl Sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [tetrachloroplatinate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein; [Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; anethole inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Cannabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA]; Dronabinol inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2 protein]; Dronabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; isoeugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; KN 93 inhibits the reaction [Cannabinol promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2 protein] |
CTD |
PMID:1371491 PMID:7815356 PMID:8658534 PMID:8662742 PMID:9439728 PMID:9571986 PMID:9925799 PMID:11592964 PMID:11809870 PMID:12165276 PMID:12411406 PMID:12421932 PMID:12749906 PMID:12812920 PMID:15379866 PMID:15477007 PMID:15588918 PMID:16055081 PMID:16154495 PMID:16168555 PMID:16241859 PMID:16374615 PMID:16531003 PMID:17051331 PMID:17572062 PMID:17615583 PMID:17630204 PMID:17685462 PMID:18423386 PMID:19277450 PMID:19880376 PMID:21075198 PMID:21511917 PMID:21569788 PMID:22398747 PMID:22561169 PMID:23134680 PMID:23941771 PMID:24603311 PMID:25073960 PMID:25770929 PMID:26343699 PMID:29594315 PMID:29777833 PMID:34051231 More...
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NCBI chr 2:121,932,968...121,937,672
Ensembl chr 2:120,004,862...120,009,566
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G |
Il21 |
interleukin 21 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein; tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein] |
CTD |
PMID:22077062 |
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NCBI chr 2:122,045,240...122,055,142
Ensembl chr 2:120,119,444...120,126,996
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G |
Il23r |
interleukin 23 receptor |
multiple interactions |
ISO |
1,1,1,3,3,3-hexafluoro-2-(2-fluoro-4'-((4-(pyridin-4-ylmethyl)piperazin-1-yl)methyl)-(1,1'-biphenyl)-4-yl)propan-2-ol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL23R mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL23R mRNA; Digoxin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL23R mRNA] |
CTD |
PMID:22292739 |
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NCBI chr 4:97,910,230...98,003,759
Ensembl chr 4:96,580,714...96,674,021
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G |
Il2ra |
interleukin 2 receptor subunit alpha |
multiple interactions increases expression increases secretion |
ISO EXP |
[Dichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein; [Trichloroacetic Acid co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Trichloroethylene co-treated with Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL2RA mRNA; Mesalamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein]; Sirolimus inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL2RA protein]; Sirolimus inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL2RA protein]; Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2RA protein] 2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; bathocuproine sulfonate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin co-treated with IL2 protein] results in increased expression of IL2RA protein]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA mRNA]; tetrathiomolybdate inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]] [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2RA protein |
CTD |
PMID:7815356 PMID:8586487 PMID:9766631 PMID:12421932 PMID:12749906 PMID:16979875 PMID:22398747 PMID:23134680 PMID:26343699 PMID:27865421 PMID:30171972 More...
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NCBI chr17:71,759,802...71,808,475
Ensembl chr17:66,849,974...66,898,697
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G |
Il2rb |
interleukin 2 receptor subunit beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:111,913,828...111,928,537
Ensembl chr 7:110,033,341...110,048,054
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G |
Il3 |
interleukin 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein]; Sirolimus inhibits the reaction [Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL3 protein]]; Tacrolimus inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL3 protein] [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL3 mRNA |
CTD |
PMID:1376361 PMID:16979875 |
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NCBI chr10:38,906,460...38,908,810
Ensembl chr10:38,405,716...38,408,066
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G |
Il33 |
interleukin 33 |
multiple interactions increases expression |
ISO |
FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL33 mRNA] |
CTD |
PMID:35717073 |
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NCBI chr 1:237,115,478...237,149,897
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
multiple interactions increases secretion increases expression |
ISO EXP |
4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [IL13 protein co-treated with IL4 protein co-treated with Nanotubes, Carbon] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of CASP1 protein]; [IL4 protein co-treated with IL13 protein] inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL4 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 mRNA]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; cyfluthrin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL4 protein]; hispidulin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 mRNA]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein]; IL4 protein inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the secretion of IL1B protein]; IL4 protein inhibits the reaction [Nanotubes, Carbon promotes the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with Nanotubes, Carbon] affects the expression of CASP1 mRNA]]; Leflunomide inhibits the reaction [[IL13 protein co-treated with IL4 protein] inhibits the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein]]; Luteolin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL4 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL4 protein] [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein] 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Cyclosporine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Pentamidine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [Sirolimus co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL4 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein; [Toluene 2,4-Diisocyanate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL4 protein; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 protein]]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL4 mRNA |
CTD |
PMID:1371491 PMID:8658534 PMID:9766631 PMID:10428506 PMID:12709020 PMID:12755381 PMID:12884291 PMID:15588918 PMID:16601352 PMID:16979875 PMID:17572062 PMID:17685462 PMID:18325701 PMID:19277450 PMID:21515303 PMID:22398747 PMID:25073960 PMID:25114106 PMID:26091108 PMID:29777833 PMID:31195760 More...
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NCBI chr10:38,272,003...38,277,549
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
multiple interactions increases expression increases secretion |
ISO EXP |
2-hydroxy-4-(2,2,3,3,3-pentafluoropropoxy)benzoic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; Houttuynia cordata extract inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL5 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL5 protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL5 protein] deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 mRNA]; deoxynivalenol promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL5 protein] Tetradecanoylphorbol Acetate results in increased expression of IL5 mRNA |
CTD |
PMID:1371491 PMID:8658534 PMID:12884291 PMID:16116958 PMID:16374615 PMID:17475810 PMID:17572062 PMID:17685462 PMID:18325701 More...
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NCBI chr10:38,375,132...38,378,003
Ensembl chr10:37,874,342...37,877,213
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G |
Il5ra |
interleukin 5 receptor subunit alpha |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of IL5RA mRNA |
CTD |
PMID:8049355 |
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NCBI chr 4:141,186,749...141,221,348
Ensembl chr 4:139,632,066...139,668,544
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression increases secretion |
ISO EXP |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of IL6 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of IL6 mRNA] Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA; Tetradecanoylphorbol Acetate results in increased expression of IL6 protein 3'(R)-O-beta-D-glucopyranosyl-3',4'-dihydroxanthyletin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased secretion of IL6 protein; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with 2-Propanol] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Sodium Dodecyl Sulfate] results in increased expression of and results in increased secretion of IL6 protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of IL6 protein; Acetaminophen affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; bisphenol A affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Desipramine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; fargesin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; GBA1 mutant form promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; isopraeroside IV inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; levistolide A inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; magnolin promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; monocyte locomotion inhibitory factor inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 protein]; prolinedithiocarbamate inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of IL6 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]]; SB 203580 promotes the reaction [magnolin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of IL6 protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; tepoxalin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of IL6 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased secretion of IL6 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of IL6 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA; U 0126 inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL6 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein] |
CTD |
PMID:7759567 PMID:9122163 PMID:10072544 PMID:10428506 PMID:12884291 PMID:16227999 PMID:16374615 PMID:16484594 PMID:17051331 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18434080 PMID:18958421 PMID:19118619 PMID:19416633 PMID:19665545 PMID:19910455 PMID:20043298 PMID:20423157 PMID:20438634 PMID:20709134 PMID:21515303 PMID:22322153 PMID:22398747 PMID:22643241 PMID:22981962 PMID:22986104 PMID:23399806 PMID:23535185 PMID:23835587 PMID:24131540 PMID:24951586 PMID:24964617 PMID:25128825 PMID:25818598 PMID:29777833 PMID:30254419 PMID:30496664 PMID:30524225 PMID:30696844 PMID:30919561 PMID:31351099 PMID:31904401 PMID:32662567 PMID:36075570 More...
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NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6r |
interleukin 6 receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL6R mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:177,582,020...177,646,705
Ensembl chr 2:175,298,686...175,347,536
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G |
Il9r |
interleukin 9 receptor |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IL9R mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:15,936,156...15,947,613
Ensembl chr10:15,431,706...15,441,990
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G |
Inhbc |
inhibin subunit beta C |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of INHBC mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 7:65,069,450...65,082,919
Ensembl chr 7:63,184,142...63,197,630
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G |
Ins1 |
insulin 1 |
multiple interactions |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Glucose] results in increased secretion of INS1 protein; Tetradecanoylphorbol Acetate inhibits the reaction [[INS1 protein co-treated with benzamide] results in increased activity of GPD1 protein] Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol inhibits the reaction [Glucose results in increased secretion of INS1 protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:2523799 PMID:10221768 PMID:17069794 PMID:30761839 |
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NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:251,244,973...251,245,536
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IRAK1 mRNA IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; IRAK1 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] |
CTD |
PMID:19840844 PMID:23680697 |
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NCBI chr X:156,919,927...156,929,825
Ensembl chr X:151,768,777...151,778,521
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G |
Irak3 |
interleukin-1 receptor-associated kinase 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of IRAK3 mRNA [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of IRAK3 mRNA |
CTD |
PMID:16979875 PMID:31904401 |
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NCBI chr 7:57,538,522...57,600,166
Ensembl chr 7:55,653,962...55,713,121
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G |
Ireb2 |
iron responsive element binding protein 2 |
increases activity multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of IREB2 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; pervanadate promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein]; TRH protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein] |
CTD |
PMID:10889193 |
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NCBI chr 8:64,124,152...64,207,702
Ensembl chr 8:55,228,085...55,311,611
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G |
Irf4 |
interferon regulatory factor 4 |
multiple interactions decreases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] Tetradecanoylphorbol Acetate results in decreased expression of IRF4 mRNA |
CTD |
PMID:15477007 PMID:33268675 |
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NCBI chr17:33,930,460...33,948,842
Ensembl chr17:33,721,811...33,740,070
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G |
Irf8 |
interferon regulatory factor 8 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IRF8 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr19:65,699,284...65,721,066
Ensembl chr19:48,790,588...48,811,829
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G |
Isg15 |
ISG15 ubiquitin-like modifier |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of ISG15 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:172,066,369...172,067,656
Ensembl chr 5:166,784,148...166,785,435
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G |
Itga2 |
integrin subunit alpha 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ITGA2 mRNA [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGA2 mRNA] |
CTD |
PMID:17669516 PMID:21331654 |
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NCBI chr 2:48,253,412...48,354,509
Ensembl chr 2:46,523,948...46,621,481
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G |
Itga2b |
integrin subunit alpha 2b |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein] |
CTD |
PMID:10428506 PMID:20523355 |
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NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,408,536...87,426,168
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G |
Itga5 |
integrin subunit alpha 5 |
multiple interactions increases expression |
ISO |
Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA5 mRNA] |
CTD |
PMID:24211529 |
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NCBI chr 7:136,358,097...136,381,305
Ensembl chr 7:134,478,968...134,502,837
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G |
Itga7 |
integrin subunit alpha 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGA7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 7:1,944,447...1,973,347
Ensembl chr 7:1,359,940...1,388,450
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G |
Itgal |
integrin subunit alpha L |
multiple interactions affects localization |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGAL protein] |
CTD |
PMID:20883105 |
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NCBI chr 1:191,348,424...191,386,228
Ensembl chr 1:181,918,183...181,955,732
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G |
Itgam |
integrin subunit alpha M |
multiple interactions increases expression increases localization |
ISO EXP |
2,4,5,2',4',5'-hexachlorobiphenyl inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; [salvin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of ITGAM protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA; dimemorfan inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of ITGAM mRNA]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein]; Tosyllysine Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of ITGAM protein] PMA increases expression of Itgam protein on neutrophils PMA increases expression of ITGAM protein on monocytes Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein] Tetradecanoylphorbol Acetate results in increased expression of ITGAM mRNA; Tetradecanoylphorbol Acetate results in increased expression of ITGAM protein |
CTD RGD |
PMID:10739673 PMID:11504768 PMID:16430862 PMID:16617325 PMID:18500357 PMID:19135038 PMID:19428933 PMID:21331654 PMID:26330309 PMID:29458014 PMID:30218697 PMID:34506768 PMID:36269090 PMID:8102031 PMID:18617650 More...
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RGD:329901912, RGD:329901662 |
NCBI chr 1:192,089,496...192,139,947
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgax |
integrin subunit alpha X |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGAX mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:192,140,089...192,171,151
Ensembl chr 1:182,719,609...182,740,698
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G |
Itgb2 |
integrin subunit beta 2 |
increases expression affects localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein Tetradecanoylphorbol Acetate affects the localization of ITGB2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of ITGB2 protein]; acteoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; crenatoside inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB2 protein] |
CTD |
PMID:16393473 PMID:20883105 |
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NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,061,430...11,097,600
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G |
Itgb3 |
integrin subunit beta 3 |
multiple interactions increases expression |
ISO |
10-(4'-(N-diethylamino)butyl)-2-chlorophenoxazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; tellimagrandin I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein] |
CTD |
PMID:10910098 PMID:14757314 PMID:14769215 PMID:20523355 |
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NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679
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G |
Itgb6 |
integrin subunit beta 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ITGB6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:65,454,964...65,579,179
Ensembl chr 3:45,048,044...45,121,671
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G |
Itgb8 |
integrin subunit beta 8 |
multiple interactions |
ISO |
[2-butenal co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of ITGB8 mRNA |
CTD |
PMID:24849683 |
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NCBI chr 6:146,267,982...146,351,245
Ensembl chr 6:140,127,203...140,208,476
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G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of ITPR1 protein alternative form |
CTD |
PMID:24073338 |
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NCBI chr 4:142,743,401...143,066,505
Ensembl chr 4:141,187,418...141,510,491
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G |
Ivl |
involucrin |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IVL mRNA] |
CTD |
PMID:10866668 PMID:17148446 |
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NCBI chr 2:180,842,307...180,854,646
Ensembl chr 2:178,147,061...178,149,100
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
JAK1 protein affects the reaction [[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] affects the expression of and affects the activity of CASP1 protein] |
CTD |
PMID:26091108 |
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NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:115,780,248...115,888,926
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases activity increases phosphorylation multiple interactions increases expression increases localization affects localization |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased activity of JUN protein Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; [FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein; [JUN gene mutant form results in increased activity of JUN protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which binds to DPYD promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [[FOS protein binds to JUN protein] which results in increased expression of DPYD mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein; [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] which results in decreased expression of AKR1B10 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of JUN protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; magnolin affects the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of JUN protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of JUN protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of JUN protein; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein binds to CYP1A2 enhancer]; Tetradecanoylphorbol Acetate promotes the reaction [Mitoxantrone results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; Thiopental inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein] Tetradecanoylphorbol Acetate results in increased expression of JUN; Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Phorbol 12,13-Dibutyrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Norepinephrine results in increased expression of JUN mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA] [Glucaric Acid co-treated with Resveratrol] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Glucaric Acid co-treated with Ursolic Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Heparin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of JUN protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]]; Pentosan Sulfuric Polyester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of JUN protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of JUN protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of JUN protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate results in increased activity of [JUN protein binds to FOS protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of JUN protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN]] Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUN protein; Tetradecanoylphorbol Acetate results in increased expression of JUN protein modified form |
CTD |
PMID:1730747 PMID:1932749 PMID:8219202 PMID:8386370 PMID:9067545 PMID:9122163 PMID:9242432 PMID:9580328 PMID:10381133 PMID:10484327 PMID:10620351 PMID:10693946 PMID:12169099 PMID:15263067 PMID:15477007 PMID:15705907 PMID:15944151 PMID:16116958 PMID:17148446 PMID:17360982 PMID:18551458 PMID:18628248 PMID:18755854 PMID:19000923 PMID:19225867 PMID:19282384 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20152819 PMID:20172950 PMID:20590612 PMID:20599481 PMID:21047949 PMID:21354279 PMID:22542552 PMID:22561169 PMID:23835587 PMID:25073960 PMID:25463304 PMID:25656647 PMID:26100520 PMID:26513295 PMID:27278863 PMID:28108223 PMID:30133131 PMID:30590137 PMID:30696844 PMID:30919561 PMID:31068361 More...
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NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656
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Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO EXP |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein]]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUNB protein]; Tetradecanoylphorbol Acetate promotes the reaction [FOSL1 protein binds to JUNB protein] Tetradecanoylphorbol Acetate inhibits the reaction [Calcimycin results in increased expression of JUNB mRNA] Tetradecanoylphorbol Acetate results in increased expression of JUNB mRNA Tetradecanoylphorbol Acetate results in increased expression of JUNB; Tetradecanoylphorbol Acetate results in increased expression of JUNB mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUNB protein |
CTD |
PMID:1932749 PMID:8631129 PMID:11113530 PMID:15666830 PMID:15920718 PMID:17148446 PMID:19000923 PMID:19945525 PMID:31068361 More...
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NCBI chr19:40,081,126...40,082,910
Ensembl chr19:23,176,294...23,178,035
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Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUND protein]; Tetradecanoylphorbol Acetate promotes the reaction [JUND protein binds to CYP1A2 enhancer] Tetradecanoylphorbol Acetate results in increased expression of JUND mRNA; Tetradecanoylphorbol Acetate results in increased expression of JUND protein |
CTD |
PMID:1932749 PMID:10620351 PMID:11507057 PMID:17148446 PMID:18755854 |
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NCBI chr16:18,768,093...18,769,771
Ensembl chr16:18,734,122...18,735,799
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Kcnd3 |
potassium voltage-gated channel subfamily D member 3 |
decreases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased activity of KCND3 protein alternative form |
CTD |
PMID:11709419 |
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NCBI chr 2:195,626,316...195,843,690
Ensembl chr 2:192,937,950...193,155,345
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Kcne1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
decreases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased activity of KCNE1 protein |
CTD |
PMID:1655403 |
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NCBI chr11:45,066,875...45,080,024
Ensembl chr11:31,580,742...31,593,901
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Kcnip2 |
potassium voltage-gated channel interacting protein 2 |
decreases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of KCNIP2 mRNA] |
CTD |
PMID:16385079 |
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NCBI chr 1:254,590,172...254,614,437
Ensembl chr 1:244,641,150...244,664,874
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Kcnj4 |
potassium inwardly-rectifying channel, subfamily J, member 4 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [KCNJ4 protein results in decreased susceptibility to Rotenone] |
CTD |
PMID:18619942 |
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NCBI chr 7:112,927,494...112,954,547
Ensembl chr 7:111,047,094...111,074,151
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Kif20a |
kinesin family member 20A |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KIF20A mRNA |
CTD |
PMID:16979875 |
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NCBI chr18:26,504,422...26,512,908
Ensembl chr18:26,230,230...26,238,780
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Kif20b |
kinesin family member 20B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF20B mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:241,840,898...241,896,451
Ensembl chr 1:232,428,371...232,483,787
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Kif23 |
kinesin family member 23 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF23 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 8:71,293,439...71,321,911
Ensembl chr 8:62,397,948...62,425,072
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Kif2c |
kinesin family member 2C |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of KIF2C mRNA |
CTD |
PMID:19031421 |
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NCBI chr 5:135,873,925...135,899,267
Ensembl chr 5:130,637,347...130,662,637
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Klf12 |
KLF transcription factor 12 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of KLF12 mRNA |
CTD |
PMID:16979875 |
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NCBI chr15:83,037,548...83,469,998
Ensembl chr15:76,637,654...77,062,056
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Klf4 |
KLF transcription factor 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:75,074,107...75,079,182
Ensembl chr 5:70,278,972...70,283,602
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Klf6 |
KLF transcription factor 6 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:69,449,483...69,458,478
Ensembl chr17:64,531,463...64,588,570
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Kpnb1 |
karyopherin subunit beta 1 |
increases expression multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of KPNB1 protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]] |
CTD |
PMID:16365892 PMID:17615583 |
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NCBI chr10:82,642,082...82,670,856
Ensembl chr10:82,145,420...82,174,605
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Kras |
KRAS proto-oncogene, GTPase |
multiple interactions |
ISO |
Methohexital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Pentobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Secobarbital inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein]; Thiamylal inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of KRAS protein] [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRAS protein |
CTD |
PMID:15263067 PMID:16368122 |
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NCBI chr 4:179,916,255...179,949,613
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Krt18 |
keratin 18 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT18 mRNA |
CTD |
PMID:16368122 |
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NCBI chr 7:135,036,168...135,039,844
Ensembl chr 7:133,157,475...133,161,166 Ensembl chr10:133,157,475...133,161,166
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Krt8 |
keratin 8 |
multiple interactions |
ISO |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of KRT8 protein |
CTD |
PMID:16368122 |
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NCBI chr 7:135,002,886...135,010,339
Ensembl chr 7:133,124,203...133,131,728
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Lama5 |
laminin subunit alpha 5 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMA5 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:187,647,904...187,695,974
Ensembl chr 3:167,270,296...167,318,451
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Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LAMB1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:53,562,849...53,630,118
Ensembl chr 6:47,835,525...47,902,585
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Lamc2 |
laminin subunit gamma 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LAMC2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr13:67,835,199...67,894,694
Ensembl chr13:65,284,664...65,344,200
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Lck |
LCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] |
CTD |
PMID:8662792 |
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NCBI chr 5:147,172,642...147,201,267
Ensembl chr 5:141,888,326...141,903,794
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Lcp1 |
lymphocyte cytosolic protein 1 |
multiple interactions increases phosphorylation |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA; KT 5926 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of LCP1 protein] |
CTD |
PMID:14769871 PMID:15477007 |
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NCBI chr15:56,846,375...56,954,090
Ensembl chr15:50,488,149...50,544,680
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Ldlr |
low density lipoprotein receptor |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LDLR mRNA; Tetradecanoylphorbol Acetate results in increased expression of LDLR protein Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LDLR protein] |
CTD |
PMID:29499335 PMID:31068361 |
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NCBI chr 8:28,546,191...28,569,075
Ensembl chr 8:20,270,041...20,294,580
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G |
Lef1 |
lymphoid enhancer binding factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LEF1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:222,340,541...222,453,931
Ensembl chr 2:219,666,592...219,779,794
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Lgals3 |
galectin 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LGALS3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr15:23,099,795...23,111,731
Ensembl chr15:20,607,692...20,632,025
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Lgals8 |
galectin 8 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of LGALS8 mRNA; [Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Vehicle Emissions] results in increased expression of LGALS8 mRNA |
CTD |
PMID:18353537 |
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NCBI chr17:62,716,368...62,744,272
Ensembl chr17:58,028,105...58,052,764
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Lhb |
luteinizing hormone subunit beta |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]]; Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]]; Tetrachlorodibenzodioxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of LHB mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Cholera Toxin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [[Colforsin co-treated with CGB3 protein] results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [[LHB protein co-treated with Guanylyl Imidodiphosphate] results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Cyclic AMP]; Tetradecanoylphorbol Acetate inhibits the reaction [CGB3 protein results in increased chemical synthesis of Testosterone]; Tetradecanoylphorbol Acetate inhibits the reaction [LHB protein results in increased chemical synthesis of Cyclic AMP] |
CTD |
PMID:2153673 PMID:21467749 |
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NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Lif |
LIF, interleukin 6 family cytokine |
multiple interactions increases expression |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LIF mRNA Tetradecanoylphorbol Acetate results in increased expression of LIF mRNA |
CTD |
PMID:16979875 PMID:26198647 |
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NCBI chr14:83,354,602...83,364,053
Ensembl chr14:79,134,574...79,140,482
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Lmo2 |
LIM domain only 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LMO2 mRNA |
CTD |
PMID:7544155 |
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NCBI chr 3:110,810,162...110,832,895
Ensembl chr 3:90,365,883...90,377,953
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Lmo7 |
LIM domain 7 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of LMO7 mRNA |
CTD |
PMID:16979875 |
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NCBI chr15:84,981,689...85,184,554
Ensembl chr15:78,567,023...78,769,783
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Lox |
lysyl oxidase |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LOX mRNA |
CTD |
PMID:19840844 |
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NCBI chr18:48,162,889...48,175,640
Ensembl chr18:45,967,343...46,041,477
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Lpl |
lipoprotein lipase |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LPL protein [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of LPL protein [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of LPL mRNA |
CTD |
PMID:18435438 PMID:19840844 PMID:30218697 |
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NCBI chr16:25,596,205...25,621,928
Ensembl chr16:20,829,465...20,855,249
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Lrp1 |
LDL receptor related protein 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of LRP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of LRP1 protein very low density lipoprotein triglyceride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of LRP1 mRNA] |
CTD |
PMID:15910848 |
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NCBI chr 7:65,265,639...65,346,196
Ensembl chr 7:63,380,356...63,460,910
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Ltbp4 |
latent transforming growth factor beta binding protein 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:91,727,769...91,759,822
Ensembl chr 1:82,600,136...82,632,178
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Lum |
lumican |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of LUM mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:34,245,323...34,252,510
Ensembl chr 7:32,358,614...32,365,793
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Mad1l1 |
mitotic arrest deficient 1 like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MAD1L1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr12:19,434,782...19,744,574
Ensembl chr12:14,320,892...14,630,703
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Mad2l1 |
mitotic arrest deficient 2 like 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MAD2L1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 4:97,236,419...97,247,603
Ensembl chr 4:95,906,817...95,913,470
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Madd |
MAP-kinase activating death domain |
decreases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased methylation of MADD gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of MADD gene] |
CTD |
PMID:32135139 |
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NCBI chr 3:97,570,141...97,613,688
Ensembl chr 3:77,114,314...77,157,701
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G |
Magi1 |
membrane associated guanylate kinase, WW and PDZ domain containing 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAGI1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 4:127,762,590...128,368,228
Ensembl chr 4:126,206,816...126,811,691
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Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; E2F4 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; juglone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein] |
CTD |
PMID:20479004 |
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NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690 Ensembl chr16:49,665,791...49,677,690
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
multiple interactions increases activity increases phosphorylation |
ISO |
[2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; MAP2K1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K1 protein] Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein 3,5,3',4',5'-pentahydroxy-stilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] |
CTD |
PMID:8816498 PMID:11861786 PMID:16945329 PMID:17693661 PMID:18767048 PMID:20479004 More...
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NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:64,683,449...64,755,147
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G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
multiple interactions increases phosphorylation |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MAP2K2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] |
CTD |
PMID:11861786 PMID:15477007 PMID:20479004 PMID:30218697 |
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NCBI chr 7:9,241,449...9,264,216
Ensembl chr 7:8,580,905...8,610,243
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
multiple interactions |
ISO |
Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:15944151 |
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NCBI chr10:50,842,348...50,947,063
Ensembl chr10:50,344,915...50,447,993
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Map2k6 |
mitogen-activated protein kinase kinase 6 |
multiple interactions |
ISO |
[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; pyrazolanthrone inhibits the reaction [[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate]; SB 203580 inhibits the reaction [[MAP2K6 gene mutant form results in increased activity of MAP2K6 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate] |
CTD |
PMID:27278863 |
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NCBI chr10:95,872,747...95,987,747
Ensembl chr10:95,373,204...95,488,293
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G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
multiple interactions |
ISO |
[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate; pyrazolanthrone inhibits the reaction [[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate]; SB 203580 inhibits the reaction [[MAP3K1 gene mutant form results in increased activity of MAP3K1 protein] which results in increased susceptibility to Tetradecanoylphorbol Acetate] |
CTD |
PMID:27278863 |
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NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:43,350,098...43,414,463
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G |
Map3k12 |
mitogen activated protein kinase kinase kinase 12 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MAP3K12 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:135,507,082...135,527,396
Ensembl chr 7:133,630,835...133,640,789
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G |
Map3k14 |
mitogen-activated protein kinase kinase kinase 14 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MAP3K14 mRNA |
CTD |
PMID:10910055 |
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NCBI chr10:88,665,417...88,715,669
Ensembl chr10:88,165,351...88,215,523
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation increases activity increases expression |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein; [Resveratrol results in decreased activity of MAPK1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; Bee Venoms promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK1 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; MAPK1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Acrylonitrile results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK1 protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of MAPK1 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Colforsin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK1 protein]; Pertussis Toxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Colforsin results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK1 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of MAPK1 protein modified form]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein] Tetradecanoylphorbol Acetate results in increased expression of MAPK1; Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein |
CTD |
PMID:8616849 PMID:8816498 PMID:9545260 PMID:9728050 PMID:10037446 PMID:10660688 PMID:10874129 PMID:10993886 PMID:11145705 PMID:11195782 PMID:11532878 PMID:11551972 PMID:11583584 PMID:11687581 PMID:11728381 PMID:11861786 PMID:12083801 PMID:12115659 PMID:12720544 PMID:12761878 PMID:12781867 PMID:14511371 PMID:14610070 PMID:14739659 PMID:14975926 PMID:15122579 PMID:15385614 PMID:15477007 PMID:15537826 PMID:15542774 PMID:15654655 PMID:15666830 PMID:15728660 PMID:15944151 PMID:15978937 PMID:16091123 PMID:16099101 PMID:16251475 PMID:16474181 PMID:16838270 PMID:16877402 PMID:17080406 PMID:17114644 PMID:17306214 PMID:17309078 PMID:17693661 PMID:17767925 PMID:18423386 PMID:18628248 PMID:18647594 PMID:19161993 PMID:19282384 PMID:19375915 PMID:19416633 PMID:19447859 PMID:19804834 PMID:19945525 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20152819 PMID:20188714 PMID:20381601 PMID:20479004 PMID:20590612 PMID:20599481 PMID:20660715 PMID:20709134 PMID:21107699 PMID:21295103 PMID:21354279 PMID:21375462 PMID:22230296 PMID:22245252 PMID:22353212 PMID:22465218 PMID:22542552 PMID:22561169 PMID:22760862 PMID:23134680 PMID:23253724 PMID:23775084 PMID:24211529 PMID:24632454 PMID:25128825 PMID:25463304 PMID:25540590 PMID:25656647 PMID:25818598 PMID:25866363 PMID:25920576 PMID:26537528 PMID:27432484 PMID:28601556 PMID:28731287 PMID:30133131 PMID:30259628 PMID:30590137 PMID:30696844 PMID:30919561 PMID:31351099 PMID:32510591 PMID:32519806 PMID:34144024 PMID:35608139 PMID:36413041 PMID:37562720 More...
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NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions increases activity increases phosphorylation |
ISO |
SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK14 protein]; Tetradecanoylphorbol Acetate promotes the reaction [arsenic trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein] Tetradecanoylphorbol Acetate results in increased activity of MAPK14 protein Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:12781867 PMID:14610070 PMID:15944151 PMID:15949478 PMID:16838270 PMID:17309078 More...
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NCBI chr20:6,751,288...6,812,294
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation increases activity increases expression |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein; [Resveratrol results in decreased activity of MAPK1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Resveratrol results in decreased activity of MAPK3 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased phosphorylation of MAPK3 protein; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK3 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; Bee Venoms promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Fulvestrant inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in increased phosphorylation of MAPK3 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Linoleic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; mangiferin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; MAPK3 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Okadaic Acid promotes the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Acrylonitrile results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Glucose deficiency results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [lead acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased phosphorylation of MAPK3 protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of MAPK3 protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [[Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Dinoprost affects the localization of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein 1-Butanol affects the reaction [RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Cadmium Chloride] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein; AG 1879 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; EGFR gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; geldanamycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased phosphorylation of MAPK3 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Ro 32-0432 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; RTKI cpd inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of MAPK3 protein]; SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of MAPK3 protein modified form]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased phosphorylation of MAPK3 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] Tetradecanoylphorbol Acetate results in increased expression of MAPK3; Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein |
CTD |
PMID:8616849 PMID:8816498 PMID:9545260 PMID:10037446 PMID:10660688 PMID:10874129 PMID:10993886 PMID:11145705 PMID:11195782 PMID:11532878 PMID:11583584 PMID:11687581 PMID:11728381 PMID:11861786 PMID:12083801 PMID:12115659 PMID:12720544 PMID:12761878 PMID:12781867 PMID:12782152 PMID:14511371 PMID:14610070 PMID:14739659 PMID:14975926 PMID:15122579 PMID:15385614 PMID:15477007 PMID:15537826 PMID:15542774 PMID:15654655 PMID:15666830 PMID:15728660 PMID:15944151 PMID:15978937 PMID:16091123 PMID:16099101 PMID:16251475 PMID:16474181 PMID:16838270 PMID:16877402 PMID:17080406 PMID:17114644 PMID:17306214 PMID:17309078 PMID:17693661 PMID:17767925 PMID:18423386 PMID:18628248 PMID:18647594 PMID:19161993 PMID:19282384 PMID:19375915 PMID:19416633 PMID:19447859 PMID:19804834 PMID:19945525 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20152819 PMID:20172950 PMID:20188714 PMID:20381601 PMID:20479004 PMID:20590612 PMID:20599481 PMID:20660715 PMID:20709134 PMID:21107699 PMID:21295103 PMID:21354279 PMID:21375462 PMID:22230296 PMID:22245252 PMID:22353212 PMID:22465218 PMID:22542552 PMID:22561169 PMID:22760862 PMID:23134680 PMID:23253724 PMID:23288142 PMID:23775084 PMID:24632454 PMID:25128825 PMID:25463304 PMID:25540590 PMID:25656647 PMID:25818598 PMID:25866363 PMID:25920576 PMID:26537528 PMID:27432484 PMID:28601556 PMID:28731287 PMID:30133131 PMID:30259628 PMID:30590137 PMID:30696844 PMID:30919561 PMID:31351099 PMID:32510591 PMID:32519806 PMID:34144024 PMID:35608139 PMID:36413041 PMID:37562720 More...
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NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK8 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MAPK8 mRNA]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; MAPK8 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein]]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK8 protein] Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:14610070 PMID:16838270 PMID:17114644 PMID:19447859 PMID:20172950 PMID:20381601 PMID:20599481 PMID:21331654 PMID:21354279 PMID:22353212 PMID:23715767 PMID:25073960 PMID:25496033 PMID:25818598 PMID:30133131 PMID:30259628 More...
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NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk8ip1 |
mitogen-activated protein kinase 8 interacting protein 1 |
multiple interactions |
EXP |
MAPK8IP1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA] |
CTD |
PMID:11513749 |
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NCBI chr 3:98,810,540...98,829,302
Ensembl chr 3:78,355,048...78,372,884
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases phosphorylation |
ISO |
Chenodeoxycholic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; GW 4064 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; Manganese promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:16838270 PMID:17693661 PMID:19447859 PMID:20599481 PMID:21354279 PMID:22353212 PMID:22561169 PMID:25496033 PMID:25818598 PMID:30133131 PMID:30259628 More...
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NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,169,675...34,210,178
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G |
Mapkapk2 |
MAPK activated protein kinase 2 |
increases activity |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of MAPKAPK2 protein |
CTD |
PMID:9545260 |
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NCBI chr13:45,066,027...45,112,326
Ensembl chr13:42,513,762...42,560,457
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARCKS mRNA |
CTD |
PMID:19840844 |
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NCBI chr20:42,240,185...42,245,882
Ensembl chr20:40,685,315...40,691,012
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G |
Marcksl1 |
MARCKS-like 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MARCKSL1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:147,135,827...147,138,150
Ensembl chr 5:141,850,110...141,853,817
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G |
Mark1 |
microtubule affinity regulating kinase 1 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK1 protein |
CTD |
PMID:30218697 |
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NCBI chr13:98,981,727...99,086,998
Ensembl chr13:96,451,487...96,555,173
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G |
Mark2 |
microtubule affinity regulating kinase 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK2 protein |
CTD |
PMID:30218697 |
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NCBI chr 1:213,890,213...213,955,417
Ensembl chr 1:204,461,030...204,525,652
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G |
Mark3 |
microtubule affinity regulating kinase 3 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MARK3 protein |
CTD |
PMID:30218697 |
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NCBI chr 6:130,626,612...130,716,245
Ensembl chr 6:130,627,482...130,716,647
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G |
Mbl2 |
mannose binding lectin 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MBL2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:237,429,873...237,465,567
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MCL1 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 2:185,884,840...185,912,532
Ensembl chr 2:183,219,220...183,222,303
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G |
Mcm3 |
minichromosome maintenance complex component 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MCM3 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 9:30,715,602...30,733,746
Ensembl chr 9:23,219,169...23,237,314
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G |
Meox2 |
mesenchyme homeobox 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MEOX2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:59,584,025...59,644,722
Ensembl chr 6:53,856,758...53,917,467
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G |
Mertk |
MER proto-oncogene, tyrosine kinase |
increases cleavage |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of MERTK protein |
CTD |
PMID:17047157 |
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NCBI chr 3:136,391,936...136,498,366
Ensembl chr 3:115,939,351...116,046,554
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G |
Mest |
mesoderm specific transcript |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MEST mRNA |
CTD |
PMID:31904401 |
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NCBI chr 4:60,321,814...60,332,288
Ensembl chr 4:59,354,447...59,366,145
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
multiple interactions |
ISO |
MGMT protein results in decreased susceptibility to [Methylnitrosourea co-treated with 9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MGMT mRNA |
CTD |
PMID:12663516 PMID:31904401 |
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NCBI chr 1:201,140,832...201,367,481
Ensembl chr 1:191,710,930...191,937,756
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G |
Mif |
macrophage migration inhibitory factor |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MIF mRNA; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [MIF protein binds to Heparan Sulfate Proteoglycans]]; Tetradecanoylphorbol Acetate inhibits the reaction [MIF protein binds to Heparan Sulfate Proteoglycans] |
CTD |
PMID:9122163 PMID:26852939 |
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NCBI chr20:12,767,138...12,791,222
Ensembl chr20:12,790,902...12,799,504 Ensembl chr 4:12,790,902...12,799,504
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G |
Mir125b1 |
microRNA 125b-1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MIR125B1 mRNA |
CTD |
PMID:33268675 |
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NCBI chr 8:50,850,036...50,850,122
Ensembl chr 8:41,952,966...41,953,052
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G |
Mir146a |
microRNA 146a |
multiple interactions increases expression |
ISO |
hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MIR146A mRNA]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]]; MIR146A mRNA affects the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of NFKBIA protein] |
CTD |
PMID:30090394 |
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NCBI chr10:28,349,996...28,350,090
Ensembl chr10:27,848,516...27,848,610
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G |
Mir155 |
microRNA 155 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MIR155 mRNA |
CTD |
PMID:33268675 |
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NCBI chr11:37,261,114...37,261,178
Ensembl chr11:23,774,654...23,774,718
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G |
Mki67 |
marker of proliferation Ki-67 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MKI67 protein |
CTD |
PMID:22981962 |
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NCBI chr 1:199,926,150...199,952,847
Ensembl chr 1:190,496,319...190,522,762
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G |
Mknk1 |
MAPK interacting serine/threonine kinase 1 |
multiple interactions increases phosphorylation increases activity |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]]; [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]; SB 203580 promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MKNK1 protein]]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MKNK1 protein] |
CTD |
PMID:9545260 PMID:12781867 |
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NCBI chr 5:129,318,128...129,357,641
Ensembl chr 5:129,318,170...129,357,639
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G |
Mme |
membrane metallo-endopeptidase |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of MME protein |
CTD |
PMID:16997790 |
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NCBI chr 2:149,806,826...149,957,381
Ensembl chr 2:147,722,086...147,803,792
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions increases expression |
ISO |
BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Dihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; mibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP1 protein |
CTD |
PMID:8798622 PMID:16176868 PMID:20004183 PMID:20858459 |
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NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions increases expression |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP13 protein |
CTD |
PMID:19656660 PMID:20004183 |
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NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp14 |
matrix metallopeptidase 14 |
multiple interactions increases expression |
ISO |
3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP14 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP14 protein |
CTD |
PMID:20152819 PMID:20599481 PMID:21354279 |
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NCBI chr15:31,857,824...31,867,049
Ensembl chr15:27,887,727...27,899,864
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G |
Mmp2 |
matrix metallopeptidase 2 |
increases expression increases activity multiple interactions increases secretion |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein; Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP2 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP2 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; oxophenylarsine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP2 protein; tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein modified form]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein]; Vorinostat inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP2 protein] |
CTD |
PMID:10455257 PMID:10569804 PMID:15962302 PMID:17498959 PMID:18155510 PMID:19375915 PMID:20152819 PMID:20590612 PMID:20599481 PMID:27163855 PMID:31545954 More...
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NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp21 |
matrix metallopeptidase 21 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MMP21 mRNA |
CTD |
PMID:16984259 |
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NCBI chr 1:197,910,178...197,915,847
Ensembl chr 1:188,480,186...188,485,855
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions increases expression |
ISO |
BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Dihydrotestosterone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Metribolone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; mibolerone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein]; Tretinoin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP3 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP3 protein |
CTD |
PMID:8798622 PMID:16176868 PMID:20004183 PMID:20858459 |
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NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp7 |
matrix metallopeptidase 7 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of MMP7 mRNA |
CTD |
PMID:8798622 |
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NCBI chr 8:13,133,043...13,140,761
Ensembl chr 8:4,848,186...4,855,902
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G |
Mmp8 |
matrix metallopeptidase 8 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MMP8 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 8:13,008,873...13,018,729
Ensembl chr 8:4,724,029...4,733,520
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases secretion increases expression increases activity |
ISO EXP |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MMP9 mRNA; [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of MMP9 protein; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; TAC 101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Quercetin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein]; wogonin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased activity of MMP9 protein] Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein Tetradecanoylphorbol Acetate results in increased secretion of MMP9 mRNA; Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [10-nitro-oleic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; 3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine promotes the reaction [Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine co-treated with kahweol acetate] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with pyrazolanthrone] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; [kahweol acetate co-treated with SB 203580] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 mRNA]; ascofuranone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Beclomethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Bee Venoms inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; CAMK1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; cordycepin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Curcumin promotes the reaction [3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; Curcumin promotes the reaction [4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Doxycycline inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]]; geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; glycitein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Hesperidin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; HMOX1 protein affects the reaction [Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Hydroxamic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; iron protoporphyrin IX inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; N-2-(4-bromophenyl) ethyl caffeamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; naringin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Nitrites inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; oxophenylarsine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; SB 203580 promotes the reaction [3,5-bis(2-fluorobenzylidene)piperidin-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Sildenafil Citrate promotes the reaction [Atorvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; solithromycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of MMP9 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein; Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein; tomatidine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; tricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of and results in increased activity of MMP9 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Vanadates inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein]; Vorinostat inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]; W 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein]; wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Y 27632 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MMP9 protein] |
CTD |
PMID:9848099 PMID:10455257 PMID:10569804 PMID:12745093 PMID:14515793 PMID:14627504 PMID:14700523 PMID:15728660 PMID:15962302 PMID:16574429 PMID:16647178 PMID:17055343 PMID:17114644 PMID:17498959 PMID:18155510 PMID:18628248 PMID:19205902 PMID:19375915 PMID:19447859 PMID:19804834 PMID:19969058 PMID:20043135 PMID:20082219 PMID:20093109 PMID:20138977 PMID:20152819 PMID:20188714 PMID:20590612 PMID:20599481 PMID:21295103 PMID:21354279 PMID:21454668 PMID:22245252 PMID:22523472 PMID:22595400 PMID:22634262 PMID:22696189 PMID:23253724 PMID:23288142 PMID:23359665 PMID:23519560 PMID:23899529 PMID:24211270 PMID:25656647 PMID:25866363 PMID:26614570 PMID:26807887 PMID:27163855 PMID:28731287 PMID:30133131 PMID:30259628 PMID:30590137 PMID:30696844 PMID:30766661 PMID:31545954 PMID:32519806 PMID:34626302 PMID:35364107 PMID:36413041 More...
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NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpo |
myeloperoxidase |
multiple interactions increases expression increases activity increases secretion |
ISO |
[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; [Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein; Carvedilol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MPO protein]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; CMI 392 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO protein]; GSK484 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; Irinotecan promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; phenethyl isothiocyanate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Dimethyl Sulfoxide] results in increased activity of MPO protein]; Potassium Cyanide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Tetradecanoylphorbol Acetate promotes the reaction [Dimethyl Sulfoxide results in increased expression of MPO mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased oxidation of 1,2-diaminobenzene] 12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 2-(4-hydroxy-3,5-dimethylphenyl)-5-methoxy-3-methylindole inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; 7-(3-(2-(cyclopropylmethyl)-3-methoxy-4-((methylamino)carbonyl)phenoxy)propoxy)-3,4-dihydro-8-propyl-2H-1-benzopyran-2-propanoic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; centipedic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; E 6080 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Mangifera indica extract inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MPO]; SC 41930 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein]; Tetradecanoylphorbol Acetate promotes the reaction [MPO protein results in increased metabolism of Hydrogen Peroxide]; zileuton inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] |
CTD |
PMID:3030588 PMID:7812673 PMID:8113982 PMID:8273558 PMID:10381133 PMID:11529688 PMID:16601795 PMID:16716910 PMID:18670081 PMID:18987595 PMID:22036979 PMID:22906169 PMID:26187476 PMID:38341106 More...
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NCBI chr10:73,092,124...73,102,057
Ensembl chr10:72,594,661...72,604,819
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G |
Mpp1 |
MAGUK p55 scaffold protein 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MPP1 mRNA |
CTD |
PMID:19840844 |
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G |
Mrc1 |
mannose receptor, C type 1 |
multiple interactions increases expression |
ISO |
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MRC1 protein] Tetradecanoylphorbol Acetate results in increased expression of MRC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MRC1 protein |
CTD |
PMID:26497364 PMID:32135139 |
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NCBI chr17:82,157,725...82,239,411
Ensembl chr17:77,249,187...77,330,857
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G |
Ms4a2 |
membrane spanning 4-domains A2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MS4A2 mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of MS4A2 mRNA] |
CTD |
PMID:21331654 |
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NCBI chr 1:217,864,855...217,873,934
Ensembl chr 1:208,440,361...208,448,310
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G |
Msln |
mesothelin |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MSLN mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:15,276,489...15,285,921
Ensembl chr10:14,771,961...14,777,643
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G |
Msr1 |
macrophage scavenger receptor 1 |
multiple interactions increases expression |
ISO |
1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; [Zinc Oxide analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MSR1 protein; acetovanillone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; bisdemethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Deferoxamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; Sodium Benzoate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form]; TEMPO inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]; Thioctic Acid inhibits the reaction [Arsenic Trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA]] Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA alternative form |
CTD |
PMID:9614211 PMID:16484594 PMID:21315065 PMID:23386263 PMID:24746987 |
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NCBI chr16:59,421,250...59,507,070
Ensembl chr16:52,717,732...52,799,676
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G |
Mt1 |
metallothionein 1 |
multiple interactions increases response to substance |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MT1 mRNA MT1 results in increased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:9506445 PMID:19840844 |
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NCBI chr19:10,831,959...10,832,975
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049 Ensembl chr X:10,826,032...10,827,049
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G |
Mt2 |
metallothionein 2 |
multiple interactions increases response to substance increases expression |
ISO |
[indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MT2A mRNA; BAG1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MT2A mRNA] [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MT2 mRNA MT2 results in increased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:9506445 PMID:18958680 PMID:20858459 PMID:31904401 |
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NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784
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G |
Mtor |
mechanistic target of rapamycin kinase |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of MTOR protein |
CTD |
PMID:31068361 |
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NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311
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G |
Muc1 |
mucin 1, cell surface associated |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MUC1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:176,933,312...176,938,497
Ensembl chr 2:174,635,995...174,640,733
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G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions increases secretion increases expression |
EXP ISO |
resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein] Tetradecanoylphorbol Acetate results in increased secretion of MUC5AC protein Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA; Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein 2''-O-acetyl-polygalacin D2 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; deapi-platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC protein]; deapi-platycodin D promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of MUC5AC protein]; platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; platycodin D3 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MUC5AC mRNA] |
CTD |
PMID:22213337 PMID:24290472 PMID:25590691 |
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NCBI chr 1:206,293,717...206,326,006
Ensembl chr 1:196,864,336...196,896,475
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G |
Mx1 |
MX dynamin like GTPase 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of MX1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr11:50,269,056...50,294,699
Ensembl chr11:36,799,660...36,823,507
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression increases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA; catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]; Glucose affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Mitoxantrone results in decreased expression of MYC mRNA] Tetradecanoylphorbol Acetate results in decreased expression of MYC mRNA Tetradecanoylphorbol Acetate results in increased expression of MYC; Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MYC mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MYC protein; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA] Tetradecanoylphorbol Acetate results in increased expression of MYC mRNA; Tetradecanoylphorbol Acetate results in increased expression of MYC protein |
CTD |
PMID:2558650 PMID:8219202 PMID:10381133 PMID:10739673 PMID:12749906 PMID:15477007 PMID:15949478 PMID:16368122 PMID:17106253 More...
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NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630
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G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions |
ISO |
MYD88 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; MYD88 mutant form inhibits the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] |
CTD |
PMID:23680697 |
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NCBI chr 8:127,952,161...127,956,230
Ensembl chr 8:119,074,437...119,079,415
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G |
Mylk |
myosin light chain kinase |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of MYLK mRNA |
CTD |
PMID:23519560 |
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NCBI chr11:79,288,243...79,535,450
Ensembl chr11:65,783,008...66,030,261
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G |
Mzf1 |
myeloid zinc finger 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of MZF1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:82,742,709...82,755,069
Ensembl chr 1:73,670,541...73,681,635
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G |
Naa80 |
N(alpha)-acetyltransferase 80, NatH catalytic subunit |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:117,132,957...117,136,207
Ensembl chr 8:108,253,302...108,257,563
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G |
Nap1l3 |
nucleosome assembly protein 1-like 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NAP1L3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr X:92,607,628...92,610,426
Ensembl chr X:88,347,598...88,350,393
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G |
Ncam1 |
neural cell adhesion molecule 1 |
multiple interactions affects localization |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCAM1 protein] |
CTD |
PMID:20883105 |
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NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014
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G |
Ncapg |
non-SMC condensin I complex, subunit G |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NCAPG mRNA |
CTD |
PMID:19031421 |
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NCBI chr14:69,616,473...69,645,445
Ensembl chr14:65,404,163...65,432,902
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions increases phosphorylation increases expression affects localization |
ISO |
Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 mRNA]; ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF1 protein]; ML 7 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NCF1 protein]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein] Tetradecanoylphorbol Acetate results in increased expression of NCF1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NCF1 protein |
CTD |
PMID:7575484 PMID:9794432 PMID:11172467 PMID:11246141 PMID:25980585 |
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NCBI chr12:28,121,816...28,131,080
Ensembl chr12:22,485,451...22,494,646
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G |
Ncf2 |
neutrophil cytosolic factor 2 |
multiple interactions affects localization |
ISO |
Acrolein inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NCF2 protein]; NCF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] |
CTD |
PMID:11246141 PMID:21705328 |
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NCBI chr13:67,505,492...67,536,015
Ensembl chr13:64,955,503...64,986,277
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G |
Nek2 |
NIMA-related kinase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NEK2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr13:105,936,809...105,950,054
Ensembl chr13:103,405,819...103,419,051
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G |
Nell1 |
neural EGFL like 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 1:108,845,462...109,709,858
Ensembl chr 1:99,709,793...100,573,860
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of NFATC1 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in decreased expression of NFATC1 protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of NFATC1 protein; NFATC1 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:21603612 PMID:24244623 |
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NCBI chr18:76,321,386...76,430,997
Ensembl chr18:74,046,904...74,156,028
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G |
Nfatc2 |
nuclear factor of activated T-cells 2 |
multiple interactions |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein; Acetic Acid inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein]; NFATC2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased phosphorylation of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [NFATC2 protein binds to KPNB1 protein]]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased activity of NFATC2 protein] 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] affects the localization of NFATC2 protein]; 6-methoxyflavone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]]; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of and results in decreased phosphorylation of NFATC2 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC2 protein binds to IL4 promoter]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased phosphorylation of and affects the localization of NFATC2 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased phosphorylation of and affects the localization of NFATC2 protein]; Sodium Acetate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of NFATC2 protein] |
CTD |
PMID:17615583 PMID:21603612 PMID:23941771 PMID:25114106 |
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NCBI chr 3:177,615,189...177,747,493
Ensembl chr 3:157,198,872...157,328,325
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G |
Nfatc3 |
nuclear factor of activated T-cells 3 |
multiple interactions |
ISO |
[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]; bisphenol A promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA]; nonylphenol promotes the reaction [[[Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [NFATC3 protein binds to IL4 promoter]] which results in increased expression of IL4 mRNA] NFATC3 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:12709020 PMID:21603612 |
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NCBI chr19:50,870,464...50,944,992
Ensembl chr19:33,960,852...34,035,150
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G |
Nfatc4 |
nuclear factor of activated T-cells 4 |
multiple interactions |
ISO |
NFATC4 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:21603612 |
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NCBI chr15:33,256,912...33,284,522
Ensembl chr15:29,305,535...29,314,610
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases activity increases expression |
ISO |
[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NFE2L2 protein; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]]; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of NFE2L2 protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFE2L2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [NFE2L2 protein binds to EP300 protein]; Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of NFE2L2 protein Tetradecanoylphorbol Acetate results in increased activity of NFE2L2 protein |
CTD |
PMID:20438634 PMID:24632381 |
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NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfib |
nuclear factor I/B |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NFIB mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:101,805,168...102,020,618
Ensembl chr 5:96,764,653...96,975,479
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions increases activity increases expression affects localization |
ISO EXP |
1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NFKB1 mRNA; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein; Anethole Trithione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; evodiamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; Fenretinide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein]; indole-3-carbinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; lonafarnib inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; magnolin affects the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKB1 protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKB1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]] Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein; Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein modified form [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein; [Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKB1 protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of NFKB1 protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to NFKB1 protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of NFKB1 protein |
CTD |
PMID:8573121 PMID:9122163 PMID:9973483 PMID:10692565 PMID:14527959 PMID:15090542 PMID:15322087 PMID:15710601 PMID:15811958 PMID:15905586 PMID:16007145 PMID:16230421 PMID:16376386 PMID:17498959 PMID:17767925 PMID:17984113 PMID:19539808 PMID:20858459 PMID:23835587 PMID:30133131 PMID:30919561 PMID:34626302 More...
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NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases phosphorylation increases expression decreases expression increases phosphorylation affects localization increases degradation |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased degradation of NFKBIA protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in decreased expression of NFKBIA mRNA; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased degradation of NFKBIA protein; [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased activity of and results in increased localization of RELA protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of NFKB1 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased degradation of NFKBIA protein]; capsiate analog inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Plant Preparations] results in increased degradation of NFKBIA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased degradation of NFKBIA protein]; Clenbuterol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Dobutamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NFKBIA protein]; MIR146A mRNA affects the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of NFKBIA protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1B protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1RN protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1B protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased degradation of NFKBIA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of NFKBIA protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in decreased expression of NFKBIA protein]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased degradation of NFKBIA protein]; Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased expression of NFKBIA protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] Tetradecanoylphorbol Acetate results in increased expression of NFKBIA protein Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NFKBIA protein modified form]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of NFKBIA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Tetradecanoylphorbol Acetate results in increased degradation of and results in increased phosphorylation of NFKBIA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein |
CTD |
PMID:9434740 PMID:10072544 PMID:12115659 PMID:15330761 PMID:15477007 PMID:15502056 PMID:16174796 PMID:16343552 PMID:16376386 PMID:16474181 PMID:17588137 PMID:17767925 PMID:18551458 PMID:18958680 PMID:19416633 PMID:19665545 PMID:20026373 PMID:20043298 PMID:20152819 PMID:20155627 PMID:20206692 PMID:20438634 PMID:20584749 PMID:20858459 PMID:21354279 PMID:21515303 PMID:22322153 PMID:22542552 PMID:23535185 PMID:23899529 PMID:23941771 PMID:25073960 PMID:25540590 PMID:25590691 PMID:25656647 PMID:25818598 PMID:29462589 PMID:30090394 PMID:30590137 PMID:31068361 PMID:31351099 PMID:36075570 More...
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NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions |
ISO |
Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of NFKBIB protein |
CTD |
PMID:20026373 |
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NCBI chr 1:93,173,817...93,181,387
Ensembl chr 1:84,046,295...84,053,862
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G |
Nfkbil1 |
NFKB inhibitor like 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NFKBIL1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr20:3,595,319...3,610,295
Ensembl chr20:3,590,642...3,605,616
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G |
Nfkbiz |
NFKB inhibitor zeta |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NFKBIZ mRNA |
CTD |
PMID:31068361 |
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NCBI chr11:58,251,720...58,279,767
Ensembl chr11:44,782,676...44,810,723
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G |
Ngf |
nerve growth factor |
multiple interactions |
ISO EXP |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [Cyclosporine results in increased expression of NGF protein]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in decreased expression of NGF protein Tetradecanoylphorbol Acetate inhibits the reaction [NGF protein results in increased expression of NR4A1 mRNA] [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NGF mRNA |
CTD |
PMID:2005087 PMID:23519560 PMID:24244623 |
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NCBI chr 2:192,589,580...192,642,971
Ensembl chr 2:189,901,058...189,954,452
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G |
Nkd2 |
NKD inhibitor of WNT signaling pathway 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NKD2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:31,268,856...31,299,390
Ensembl chr 1:29,441,328...29,470,821
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G |
Nkg7 |
natural killer cell granule protein 7 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:102,981,497...102,982,564
Ensembl chr 1:93,844,902...93,845,983
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NLRP3 mRNA |
CTD |
PMID:23937860 |
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NCBI chr10:44,826,299...44,853,373
Ensembl chr10:44,328,566...44,352,811
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G |
Nmi |
N-myc (and STAT) interactor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA |
CTD |
PMID:15477007 |
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NCBI chr 3:56,824,778...56,848,891
Ensembl chr 3:36,415,607...36,439,498
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G |
Nolc1 |
nucleolar and coiled-body phosphoprotein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NOLC1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:254,870,195...254,881,070
Ensembl chr 1:244,921,377...244,932,088
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G |
Nos1 |
nitric oxide synthase 1 |
multiple interactions increases expression |
ISO |
decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS1 protein] |
CTD |
PMID:31351099 |
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NCBI chr12:44,276,011...44,456,371
Ensembl chr12:38,626,714...38,710,945
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression increases activity |
ISO EXP |
[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Plant Extracts promotes the reaction [Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein; Quercetin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [ginsenoside Rg3 results in increased expression of NOS2 protein]; wogonin inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein] Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein; [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NOS2 protein]; Chlorogenic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of NOS2 protein]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; Hydrolyzable Tannins inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; protocatechuic acid inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] which results in increased abundance of Nitrites]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of NOS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; shogaol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS2 protein] |
CTD |
PMID:12086399 PMID:14534150 PMID:14700523 PMID:16647178 PMID:18551458 PMID:18683823 PMID:19539808 PMID:20004183 PMID:20026373 PMID:20043298 PMID:20559769 PMID:23899529 PMID:24304388 PMID:24672638 PMID:25818598 PMID:26187476 PMID:31351099 PMID:32135139 PMID:32662567 More...
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NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NOS3 protein decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NOS3 protein] |
CTD |
PMID:31351099 |
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NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166
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G |
Notch3 |
notch receptor 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:11,783,550...11,834,585
Ensembl chr 7:11,133,706...11,184,025
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G |
Noxo1 |
NADPH oxidase organizer 1 |
multiple interactions |
ISO |
NOXO1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] |
CTD |
PMID:21705328 |
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NCBI chr10:14,226,473...14,230,541
Ensembl chr10:13,721,473...13,726,061
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G |
Nploc4 |
NPL4 homolog, ubiquitin recognition factor |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NPLOC4 protein |
CTD |
PMID:30218697 |
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NCBI chr10:106,152,756...106,208,306
Ensembl chr10:105,654,812...105,709,913
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G |
Nppa |
natriuretic peptide A |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA; Tetradecanoylphorbol Acetate results in increased expression of NPPA protein (+)-JQ1 compound inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA protein]; MAPK8IP1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA]; Mifepristone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NPPA mRNA] |
CTD |
PMID:11470465 PMID:11513749 PMID:16533503 PMID:19244478 PMID:23939492 |
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NCBI chr 5:163,712,184...163,713,493
Ensembl chr 5:158,429,042...158,430,351
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G |
Npy |
neuropeptide Y |
multiple interactions decreases expression |
ISO EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [NPY protein promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein]] Tetradecanoylphorbol Acetate results in decreased expression of NPY protein |
CTD |
PMID:10660688 PMID:19912776 |
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NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495
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G |
Npy1r |
neuropeptide Y receptor Y1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of NPY1R mRNA |
CTD |
PMID:31904401 |
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NCBI chr16:27,804,416...27,814,070
Ensembl chr16:23,037,789...23,046,759
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions increases expression |
ISO |
2-tert-butylhydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NQO1 mRNA; Arsenicals promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein Tetradecanoylphorbol Acetate results in increased expression of NQO1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein ARNT protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Copper results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Lead results in increased expression of NQO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Mercury results in increased expression of NQO1 protein] |
CTD |
PMID:16979875 PMID:18752316 PMID:24481452 PMID:24632381 |
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NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557
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G |
Nqo2 |
N-ribosyldihydronicotinamide:quinone dehydrogenase 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NQO2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr17:31,114,825...31,144,062
Ensembl chr17:30,909,187...30,938,320
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G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
multiple interactions decreases expression |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA]; NR0B1 protein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NR0B1 protein binds to STAR promoter] Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 protein |
CTD |
PMID:18787026 PMID:19282384 |
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NCBI chr X:54,707,658...54,711,786
Ensembl chr X:50,756,886...50,761,011
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NR1H2 mRNA |
CTD |
PMID:31011801 |
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NCBI chr 1:104,178,483...104,183,863
Ensembl chr 1:95,041,967...95,047,377
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NR1H3 mRNA |
CTD |
PMID:31011801 |
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NCBI chr 3:97,614,616...97,632,053
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Dexamethasone results in increased expression of NR1I2 protein] |
CTD |
PMID:18473823 |
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NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
decreases expression multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of NR3C1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of NR3C1 protein [Fluticasone co-treated with Tetradecanoylphorbol Acetate] affects the localization of NR3C1 protein; Salmeterol Xinafoate promotes the reaction [[Fluticasone co-treated with Tetradecanoylphorbol Acetate] affects the localization of NR3C1 protein] Tetradecanoylphorbol Acetate results in increased expression of NR3C1 mRNA |
CTD |
PMID:15860753 PMID:16533503 PMID:21533367 |
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NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375
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G |
Nr3c2 |
nuclear receptor subfamily 3, group C, member 2 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of NR3C2 mRNA |
CTD |
PMID:16533503 |
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NCBI chr19:47,619,853...47,964,089
Ensembl chr19:30,715,648...31,059,885
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G |
Nr4a1 |
nuclear receptor subfamily 4, group A, member 1 |
affects localization multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate affects the localization of NR4A1 protein Tetradecanoylphorbol Acetate inhibits the reaction [Carbachol results in increased expression of NR4A1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [NGF protein results in increased expression of NR4A1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of NR4A1 mRNA Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NR4A1 protein]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of NR4A1 protein] [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A1 mRNA |
CTD |
PMID:2005087 PMID:12376465 PMID:16979875 PMID:18787026 PMID:19282384 PMID:28754437 More...
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NCBI chr 7:134,247,153...134,268,044
Ensembl chr 7:132,374,840...132,389,297
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of NR4A3 mRNA |
CTD |
PMID:15477007 PMID:16979875 |
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NCBI chr 5:67,157,141...67,198,287
Ensembl chr 5:62,361,822...62,402,733
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G |
Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
multiple interactions |
ISO |
NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA] |
CTD |
PMID:18787026 |
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NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:22,465,502...22,486,328
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G |
Nr5a2 |
nuclear receptor subfamily 5, group A, member 2 |
multiple interactions |
ISO |
alitretinoin inhibits the reaction [NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA]]; NR5A2 protein promotes the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CYP19A1 mRNA] |
CTD |
PMID:16357189 |
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NCBI chr13:50,865,253...50,985,107
Ensembl chr13:48,316,301...48,433,326
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G |
Nrg1 |
neuregulin 1 |
multiple interactions |
ISO |
[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA; U 0126 inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of NRG1 mRNA] |
CTD |
PMID:21047912 |
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NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884
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G |
Nrxn2 |
neurexin 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of NRXN2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 1:213,155,673...213,271,526
Ensembl chr 1:203,735,753...203,842,297
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G |
Nsg2 |
neuronal vesicle trafficking associated 2 |
increases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of NSG2 gene] |
CTD |
PMID:32135139 |
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NCBI chr10:16,106,073...16,165,915
Ensembl chr10:15,601,596...15,661,441
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G |
Ntf3 |
neurotrophin 3 |
multiple interactions increases expression |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Histamine results in increased expression of NTF3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [imetit results in increased expression of NTF3 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [methylhistaprodifen results in increased expression of NTF3 protein] Tetradecanoylphorbol Acetate results in increased expression of NTF3 protein |
CTD |
PMID:19854260 PMID:21276809 |
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NCBI chr 4:160,601,161...160,670,623
Ensembl chr 4:158,914,957...158,984,596
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G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of NTRK2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136
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G |
Nts |
neurotensin |
multiple interactions decreases activity |
ISO |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Okadaic Acid promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Sucrose promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Go 6976 results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NTS protein results in increased chemical synthesis of Inositol Phosphates]; Tetradecanoylphorbol Acetate inhibits the reaction [Ro 31-8220 results in increased activity of NTS protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Staurosporine results in increased activity of NTS protein] |
CTD |
PMID:18313772 |
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NCBI chr 7:39,451,484...39,460,888
Ensembl chr 7:37,564,533...37,574,423
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G |
Nup54 |
nucleoporin 54 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NUP54 mRNA |
CTD |
PMID:19000923 |
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NCBI chr14:15,901,936...15,920,335
Ensembl chr14:15,617,679...15,636,028
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G |
Nusap1 |
nucleolar and spindle associated protein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of NUSAP1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:127,057,220...127,092,779
Ensembl chr 3:106,603,289...106,633,624
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G |
Oas2 |
2'-5' oligoadenylate synthetase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OAS2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr12:41,464,568...41,492,036
Ensembl chr12:35,806,759...35,829,371
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G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions increases activity increases expression |
ISO |
pyridaben inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; Rotenone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein] bullatacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Colchicine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Croton Oil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; deguelin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]; Glutathione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron, Dietary deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Iron-Dextran Complex promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; phenethyl isothiocyanate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein]; Podophyllotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Sodium Selenite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Tamoxifen inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Vinblastine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; Vitamin E inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of ODC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of ODC1 protein |
CTD |
PMID:1923905 PMID:2591024 PMID:3098411 PMID:7653998 PMID:9270009 PMID:9834970 PMID:10517978 PMID:10866668 PMID:11243714 PMID:12065085 PMID:12201673 PMID:12504893 PMID:12628514 PMID:14997284 PMID:15920718 PMID:19161993 PMID:22760862 PMID:22986104 More...
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NCBI chr 6:46,058,439...46,065,148
Ensembl chr 6:40,329,964...40,336,440
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G |
Olfml2a |
olfactomedin-like 2A |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OLFML2A mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:43,098,299...43,127,621
Ensembl chr 3:22,688,598...22,717,909
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G |
Olr1 |
oxidized low density lipoprotein receptor 1 |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA]; demethoxycurcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OLR1 mRNA] |
CTD |
PMID:23386263 |
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NCBI chr 4:164,612,460...164,635,082
Ensembl chr 4:162,926,439...162,948,523
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G |
Olr1523 |
olfactory receptor 1523 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of OR4D1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:73,205,498...73,206,439
Ensembl chr10:72,707,063...72,715,311
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G |
Oprm1 |
opioid receptor, mu 1 |
increases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA [phorbol 13-acetate 12-myristate cotreatment with morphine] decreases expression of Oprm1 protein in cultured astrocytes [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] Sulfasalazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of OPRM1 mRNA] |
CTD RGD |
PMID:11901219 PMID:18652891 PMID:28341892 |
RGD:597978120 |
NCBI chr 1:45,565,371...45,818,722
Ensembl chr 1:43,160,057...43,413,409
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G |
Otc |
ornithine transcarbamylase |
multiple interactions increases activity |
EXP |
[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]; Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; didemnins inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Calcimycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Gossypol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Quinacrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of OTC protein]; Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein] |
CTD |
PMID:3097147 |
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NCBI chr X:15,126,358...15,202,473
Ensembl chr X:12,453,834...12,566,918
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G |
P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of P2RX7 mRNA |
CTD |
PMID:23519560 |
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NCBI chr12:39,550,531...39,594,984
Ensembl chr12:33,879,745...33,934,619
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G |
P2ry1 |
purinergic receptor P2Y1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of P2RY1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:147,391,661...147,397,870
Ensembl chr 2:145,241,849...145,248,457
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G |
P2ry2 |
purinergic receptor P2Y2 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [P2RY2 protein results in increased uptake of Calcium] |
CTD |
PMID:17003265 |
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NCBI chr 1:164,764,119...164,779,578
Ensembl chr 1:155,351,165...155,367,632
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G |
Pafah1b1 |
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 |
multiple interactions |
EXP |
PAFAH1B1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of Phosphatidylcholines] |
CTD |
PMID:12013527 |
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NCBI chr10:60,031,441...60,090,259
Ensembl chr10:59,534,117...59,591,808
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G |
Pak3 |
p21 (RAC1) activated kinase 3 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PAK3 mRNA |
CTD |
PMID:19031421 |
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NCBI chr X:111,912,967...112,171,037
Ensembl chr X:107,260,898...107,368,314
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G |
Pak6 |
p21 (RAC1) activated kinase 6 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PAK6 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:126,092,576...126,128,320
Ensembl chr 3:105,638,653...105,672,975
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G |
Papss2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PAPSS2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:239,867,597...239,952,614
Ensembl chr 1:230,454,426...230,539,331
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G |
Pard6b |
par-6 family cell polarity regulator beta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PARD6B mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:177,209,429...177,230,509
Ensembl chr 3:156,790,540...156,811,622
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions increases activity affects response to substance |
ISO |
3-aminobenzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; [Glucose deficiency co-treated with Tetradecanoylphorbol Acetate] results in increased cleavage of PARP1 protein; Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; CAT protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [cholix toxin, Vibrio cholerae results in increased cleavage of PARP1 protein] PARP1 protein affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:2120135 PMID:2126186 PMID:16323285 PMID:17309078 PMID:28087840 |
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NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404
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G |
Parp2 |
poly (ADP-ribose) polymerase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PARP2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr15:26,494,722...26,517,893
Ensembl chr15:24,034,106...24,044,338
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G |
Pbk |
PDZ binding kinase |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PBK mRNA |
CTD |
PMID:19031421 |
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NCBI chr15:44,198,506...44,209,572
Ensembl chr15:40,023,002...40,034,014
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G |
Pcbp2 |
poly(rC) binding protein 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCBP2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 7:135,483,702...135,508,254
Ensembl chr 7:133,605,573...133,629,863
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G |
Pcdha2 |
protocadherin alpha 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCDHA2 mRNA |
CTD |
PMID:16979875 |
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Ensembl chr18:28,581,225...28,846,211
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions increases expression |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA; [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of PCNA protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA mRNA]; Eugenol inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PCNA protein]; Masoprocol affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PCNA mRNA]; Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]; Tacrolimus affects the reaction [Tacrolimus affects the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCNA protein]] |
CTD |
PMID:10866668 PMID:19840844 PMID:20043298 PMID:25770929 PMID:32662567 PMID:35364107 More...
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NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcolce |
procollagen C-endopeptidase enhancer |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PCOLCE mRNA |
CTD |
PMID:16979875 |
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NCBI chr12:24,720,972...24,727,287
Ensembl chr12:19,084,210...19,090,508
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G |
Pcp4 |
Purkinje cell protein 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PCP4 mRNA |
CTD |
PMID:31904401 |
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NCBI chr11:49,229,185...49,331,186
Ensembl chr11:35,800,713...35,861,725
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G |
Pdcd4 |
programmed cell death 4 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 mRNA Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of PDCD4 protein] |
CTD |
PMID:21873647 PMID:26513295 |
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NCBI chr 1:262,912,659...262,949,581
Ensembl chr 1:252,921,392...252,944,275
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G |
Pde1b |
phosphodiesterase 1B |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDE1B mRNA |
CTD |
PMID:23519560 |
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NCBI chr 7:136,505,834...136,533,034
Ensembl chr 7:134,627,322...134,654,580
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G |
Pdgfa |
platelet derived growth factor subunit A |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PDGFA mRNA Ramipril inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PDGFA mRNA] |
CTD |
PMID:10352363 PMID:10428506 |
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NCBI chr12:20,759,366...20,780,337
Ensembl chr12:15,645,541...15,666,497
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G |
Pdgfb |
platelet derived growth factor subunit B |
multiple interactions increases expression |
ISO EXP |
Ramipril inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PDGFB mRNA] Tetradecanoylphorbol Acetate inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA] |
CTD |
PMID:9650640 PMID:10352363 PMID:10428506 |
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NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdgfra |
platelet derived growth factor receptor alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PDGFRA mRNA |
CTD |
PMID:19840844 |
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NCBI chr14:33,360,027...33,408,604
Ensembl chr14:33,005,839...33,054,335
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G |
Pdia3 |
protein disulfide isomerase family A, member 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PDIA3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:128,841,781...128,865,733
Ensembl chr 3:108,388,245...108,413,236
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G |
Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PECAM1 protein Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PECAM1 protein] |
CTD |
PMID:29458014 |
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NCBI chr10:92,090,263...92,152,002
Ensembl chr10:91,590,521...91,652,116
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G |
Penk |
proenkephalin |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of PENK mRNA Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PENK mRNA] |
CTD |
PMID:11113530 |
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NCBI chr 5:21,981,381...21,987,074
Ensembl chr 5:17,183,806...17,189,129
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G |
Per1 |
period circadian regulator 1 |
multiple interactions |
ISO |
[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA; AHR protein inhibits the reaction [[Colforsin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PER1 mRNA] |
CTD |
PMID:23291558 |
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NCBI chr10:54,299,002...54,313,804
Ensembl chr10:53,805,535...53,814,431
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G |
Pgr |
progesterone receptor |
multiple interactions |
ISO |
bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of PGR mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [benz(a)anthracene results in increased expression of PGR mRNA] |
CTD |
PMID:22643241 |
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NCBI chr 8:14,354,398...14,413,271
Ensembl chr 8:6,072,673...6,131,344
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G |
Phex |
phosphate regulating endopeptidase X-linked |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PHEX mRNA |
CTD |
PMID:19000923 |
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NCBI chr X:41,422,561...41,671,226
Ensembl chr X:37,610,760...37,854,469
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G |
Phka2 |
phosphorylase kinase regulatory subunit alpha 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PHKA2 mRNA [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PYK protein |
CTD |
PMID:23519560 PMID:30218697 |
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NCBI chr X:37,979,629...38,102,656
Ensembl chr X:34,171,323...34,293,466
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G |
Pik3cb |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PIK3CB mRNA |
CTD |
PMID:23519560 |
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NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:99,594,644...99,699,663
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G |
Pik3cd |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PIK3CD mRNA |
CTD |
PMID:23519560 |
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NCBI chr 5:165,377,994...165,426,620
Ensembl chr 5:160,094,952...160,120,930
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G |
Pik3r5 |
phosphoinositide-3-kinase, regulatory subunit 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PIK3R5 mRNA |
CTD |
PMID:19000923 |
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NCBI chr10:53,631,469...53,699,550
Ensembl chr10:53,132,603...53,199,374
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G |
Pin1 |
peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
multiple interactions |
ISO |
E2F4 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; EGR1 protein promotes the reaction [PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of E2F4 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGR1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of ERBB2 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAP1LC3B protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAP2K2 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; PIN1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:20479004 |
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NCBI chr 8:27,465,538...27,477,016
Ensembl chr 8:19,189,373...19,200,785
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G |
Pla2g2a |
phospholipase A2 group IIA |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [IFNG protein promotes the reaction [decitabine results in increased expression of PLA2G2A protein]] |
CTD |
PMID:18953428 |
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NCBI chr 5:156,359,725...156,362,302
Ensembl chr 5:151,076,442...151,079,014
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G |
Pla2g4a |
phospholipase A2 group 4A |
increases phosphorylation |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of PLA2G4A protein |
CTD |
PMID:10874129 |
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NCBI chr13:64,427,921...64,572,352
Ensembl chr13:61,877,813...62,022,266
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G |
Plat |
plasminogen activator, tissue type |
increases secretion increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased secretion of PLAT protein Tetradecanoylphorbol Acetate results in increased expression of PLAT protein |
CTD |
PMID:3119194 PMID:8018658 |
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NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions increases expression increases secretion |
ISO |
arsenic trioxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of PLAU protein] Tetradecanoylphorbol Acetate results in increased expression of PLAU protein TAC 101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PLAU protein] |
CTD |
PMID:9848099 PMID:15962302 |
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NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775
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G |
Plcb2 |
phospholipase C, beta 2 |
affects localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate affects the localization of PLCB2 protein edelfosine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PLCB2 protein] |
CTD |
PMID:9295281 |
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NCBI chr 3:126,134,925...126,158,303
Ensembl chr 3:105,684,815...105,704,302
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G |
Plcg2 |
phospholipase C, gamma 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PLCG2 mRNA |
CTD |
PMID:23519560 |
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NCBI chr19:62,456,196...62,592,684
Ensembl chr19:45,547,416...45,683,930
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G |
Pld1 |
phospholipase D1 |
increases activity multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased activity of PLD1 protein toxB protein, Clostridium difficile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PLD1 protein] |
CTD |
PMID:14769825 PMID:15067002 |
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NCBI chr 2:112,777,820...112,975,857
Ensembl chr 2:110,893,608...111,047,692
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G |
Pld2 |
phospholipase D2 |
multiple interactions increases activity |
ISO EXP |
PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK3 protein] Tetradecanoylphorbol Acetate results in increased activity of PLD2 protein |
CTD |
PMID:15067002 PMID:18423386 |
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NCBI chr10:55,754,957...55,772,819
Ensembl chr10:55,256,359...55,272,808
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G |
Plek |
pleckstrin |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of PLEK protein Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
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NCBI chr14:95,598,650...95,631,326
Ensembl chr14:91,397,019...91,454,131
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G |
Plin2 |
perilipin 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PLIN2 protein |
CTD |
PMID:30218697 |
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NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:101,154,411...101,242,319
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G |
Plk1 |
polo-like kinase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PLK1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 1:186,147,658...186,157,637
Ensembl chr 1:176,716,420...176,726,400
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G |
Plxdc2 |
plexin domain containing 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PLXDC2 mRNA |
CTD |
PMID:31904401 |
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NCBI chr17:84,077,793...84,502,831
Ensembl chr17:79,196,369...79,585,282
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G |
Pnpla4 |
patatin like phospholipase domain containing 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr X:46,200,351...46,205,517
Ensembl chr X:42,305,373...42,318,552
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G |
Pole2 |
DNA polymerase epsilon 2, accessory subunit |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of POLE2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 6:93,410,713...93,448,782
Ensembl chr 6:87,674,702...87,699,305
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G |
Pot1 |
protection of telomeres 1 |
decreases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of POT1 mRNA]; [2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in increased expression of POT1 mRNA |
CTD |
PMID:26330309 |
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NCBI chr 4:55,170,821...55,228,588
Ensembl chr 4:54,205,332...54,263,042
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G |
Pou2f1 |
POU class 2 homeobox 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of POU2F1 protein |
CTD |
PMID:16241859 |
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NCBI chr13:80,653,602...80,796,279
Ensembl chr13:78,130,685...78,263,363
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G |
Pou2f2 |
POU class 2 homeobox 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:89,810,153...89,897,560
Ensembl chr 1:80,685,741...80,724,261
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G |
Pou4f3 |
POU class 4 homeobox 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of POU4F3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr18:34,641,191...34,643,783
Ensembl chr18:34,390,205...34,392,797
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions increases expression increases activity |
ISO EXP |
PPARA protein affects the reaction [Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]] Tetradecanoylphorbol Acetate results in increased expression of PPARA mRNA Tetradecanoylphorbol Acetate results in increased activity of PPARA protein |
CTD |
PMID:11701232 PMID:16042408 PMID:17360982 |
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NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
multiple interactions increases expression |
ISO |
PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CCNB1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK1 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDK4 mRNA]; PPARD protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PCNA mRNA] Tetradecanoylphorbol Acetate results in increased expression of PPARD mRNA |
CTD |
PMID:10866668 |
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NCBI chr20:6,300,527...6,365,707
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases activity increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of PPARG protein Tetradecanoylphorbol Acetate results in increased expression of PPARG mRNA; Tetradecanoylphorbol Acetate results in increased expression of PPARG protein [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in decreased activity of MAP2K1 protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; [2-chloro-5-nitrobenzanilide results in decreased activity of PPARG protein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of troglitazone]; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] affects the expression of PPARG mRNA; [Tetradecanoylphorbol Acetate results in increased expression of PPARG] which affects the susceptibility to troglitazone; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; MAP2K1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein] |
CTD |
PMID:12044893 PMID:15707588 PMID:16945329 PMID:21511917 |
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NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppbp |
pro-platelet basic protein |
multiple interactions increases expression |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PPBP mRNA Tetradecanoylphorbol Acetate results in increased expression of PPBP protein |
CTD |
PMID:15316029 PMID:23519560 |
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NCBI chr14:17,586,495...17,587,299
Ensembl chr14:17,302,326...17,303,130
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PPP1R15A mRNA |
CTD |
PMID:31068361 |
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NCBI chr 1:105,136,521...105,139,596
Ensembl chr 1:96,000,058...96,003,171
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G |
Ppp1r1b |
protein phosphatase 1, regulatory (inhibitor) subunit 1B |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PPP1R1B mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:83,843,948...83,853,063
Ensembl chr10:83,347,731...83,356,775
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G |
Ppp2ca |
protein phosphatase 2 catalytic subunit alpha |
multiple interactions |
ISO |
PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CA protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:23775084 |
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NCBI chr10:36,856,534...36,878,789
Ensembl chr10:36,358,101...36,377,862
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G |
Ppp2cb |
protein phosphatase 2 catalytic subunit beta |
multiple interactions |
ISO |
PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased activity of DNMT1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK1 protein]; PPP2CB protein affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:23775084 |
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NCBI chr16:65,261,178...65,282,658
Ensembl chr16:58,558,122...58,579,576
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G |
Prdx2 |
peroxiredoxin 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PRDX2 protein |
CTD |
PMID:20045496 |
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NCBI chr19:40,085,788...40,091,083
Ensembl chr19:23,180,930...23,186,194
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G |
Prex1 |
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PREX1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 3:175,724,939...175,875,764
Ensembl chr 3:155,306,950...155,456,688
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G |
Prf1 |
perforin 1 |
multiple interactions |
ISO |
2-tert-butylhydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of PRF1 protein |
CTD |
PMID:30171972 |
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NCBI chr20:29,789,040...29,794,550
Ensembl chr20:29,246,202...29,251,701
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G |
Prickle1 |
prickle planar cell polarity protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PRICKLE1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:126,518,587...126,614,581
Ensembl chr 7:124,639,142...124,658,113
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G |
Prkca |
protein kinase C, alpha |
multiple interactions increases expression decreases expression affects localization increases phosphorylation increases activity increases localization decreases phosphorylation |
ISO EXP |
[Ethanol results in increased localization of and results in increased activity of PRKCA protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]; [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] which results in increased expression of SOD2; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCA protein]; PRKCA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased phosphorylation of and results in increased activity of PRKCA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCA protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate results in increased activity of and affects the localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased phosphorylation of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCA protein Tetradecanoylphorbol Acetate results in increased expression of PRKCA protein modified form Tetradecanoylphorbol Acetate results in decreased expression of PRKCA protein 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCA protein; Tetradecanoylphorbol Acetate inhibits the reaction [[lead acetate results in increased abundance of Lead] which results in decreased expression of and results in decreased phosphorylation of PRKCA protein] Tetradecanoylphorbol Acetate results in increased localization of PRKCA protein Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; bicyclol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PRKCA mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCA protein]; Egtazic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; PRKCA protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate binds to and affects the localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCA protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCA protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCA protein |
CTD |
PMID:9852137 PMID:10651808 PMID:10656618 PMID:12590138 PMID:12720544 PMID:14678745 PMID:14736339 PMID:14739659 PMID:14975926 PMID:15330761 PMID:15380616 PMID:15976015 PMID:15978937 PMID:16091123 PMID:16099101 PMID:16343552 PMID:16532021 PMID:17106253 PMID:17171646 PMID:18313772 PMID:19394402 PMID:19447859 PMID:20032081 PMID:20152819 PMID:20172950 PMID:20590612 PMID:21047949 PMID:21354279 PMID:21705328 PMID:22020176 PMID:24672638 PMID:25866363 PMID:29669290 PMID:30133131 PMID:36925031 More...
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NCBI chr10:93,388,991...93,787,617
Ensembl chr10:92,894,012...93,288,012
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G |
Prkcb |
protein kinase C, beta |
multiple interactions decreases expression increases phosphorylation affects localization increases activity decreases phosphorylation |
ISO |
[Ethanol results in increased localization of and results in increased activity of PRKCB protein] promotes the reaction [Tetradecanoylphorbol Acetate results in increased abundance of Superoxides]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCB protein]; PRKCB protein affects the reaction [Tetradecanoylphorbol Acetate affects the localization of Zinc]; PRKCB protein alternative form affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCB protein] Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein; Tetradecanoylphorbol Acetate results in decreased expression of PRKCB protein modified form Tetradecanoylphorbol Acetate affects the localization of PRKCB protein; Tetradecanoylphorbol Acetate affects the localization of PRKCB protein alternative form Tetradecanoylphorbol Acetate results in increased activity of PRKCB protein Tetradecanoylphorbol Acetate results in decreased phosphorylation of PRKCB protein |
CTD |
PMID:1724372 PMID:9852137 PMID:10651808 PMID:15330761 PMID:15380616 PMID:15976015 PMID:16495082 PMID:18313772 PMID:19447859 PMID:21705328 PMID:24672638 PMID:25866363 More...
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NCBI chr 1:186,263,397...186,594,743
Ensembl chr 1:176,832,226...177,163,536
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G |
Prkcd |
protein kinase C, delta |
multiple interactions decreases expression affects localization increases activity increases phosphorylation increases localization affects phosphorylation |
ISO EXP |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKCD protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; 3-caffeoyl-4-dihydrocaffeoylquinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein]; 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein; bisindolylmaleimide I affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKCD protein]; Docosahexaenoic Acids inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCD protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKCD protein]; Oils, Volatile inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein]; Plant Oils inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased phosphorylation of PRKCD protein]; PRKCD protein affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with benz(a)anthracene]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of PRKCD protein PRKCD protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Quercetin affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCD protein Tetradecanoylphorbol Acetate results in decreased expression of PRKCD protein 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCD protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of and affects the localization of PRKCD protein Tetradecanoylphorbol Acetate results in increased localization of PRKCD protein |
CTD |
PMID:9852137 PMID:10567579 PMID:10656618 PMID:11424089 PMID:12755590 PMID:14678745 PMID:15380616 PMID:15538571 PMID:15707588 PMID:15949478 PMID:15976015 PMID:16361709 PMID:18313772 PMID:18628248 PMID:20599481 PMID:21047949 PMID:21354279 PMID:21705328 PMID:22245252 PMID:22643241 PMID:23288142 PMID:23333628 PMID:23941771 PMID:29669290 PMID:30133131 More...
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NCBI chr16:5,775,681...5,806,122
Ensembl chr16:5,769,215...5,799,352
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G |
Prkce |
protein kinase C, epsilon |
multiple interactions decreases expression affects localization increases activity |
ISO EXP |
PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCE protein Tetradecanoylphorbol Acetate results in decreased expression of PRKCE protein Tetradecanoylphorbol Acetate affects the localization of PRKCE protein [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] which results in decreased expression of PRKCE protein; Tetradecanoylphorbol Acetate results in decreased expression of PRKCE protein PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCE protein Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]; PRKCE protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein]; Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased localization of PRKCE protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKCE protein |
CTD |
PMID:11507057 PMID:12003851 PMID:12590138 PMID:14623285 PMID:14975926 PMID:16099101 PMID:16793902 PMID:18313772 PMID:21047949 PMID:21705328 PMID:24496235 More...
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NCBI chr 6:13,718,050...14,204,931
Ensembl chr 6:7,965,048...8,451,719
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G |
Prkcg |
protein kinase C, gamma |
decreases expression affects localization multiple interactions increases activity |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of PRKCG protein Tetradecanoylphorbol Acetate affects the localization of PRKCG protein naringenin inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PRKCG protein] [Tetradecanoylphorbol Acetate co-treated with Calcium] inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Morphine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Zinc promotes the reaction [OPRM1 protein binds to PRKCG protein]] Tetradecanoylphorbol Acetate results in increased activity of PRKCG protein |
CTD |
PMID:14975926 PMID:15707588 PMID:15949478 PMID:18652891 PMID:19447859 PMID:25866363 More...
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NCBI chr 1:74,748,272...74,777,611
Ensembl chr 1:65,832,855...65,859,384
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G |
Prkch |
protein kinase C, eta |
increases activity multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein [Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein] inhibits the reaction [Sirolimus results in decreased phosphorylation of RPS6 protein] |
CTD |
PMID:16832347 |
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NCBI chr 6:98,027,830...98,226,486
Ensembl chr 6:92,292,000...92,490,654
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G |
Prkci |
protein kinase C, iota |
increases localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased localization of PRKCI protein wogonin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of PRKCI protein] |
CTD |
PMID:21295103 |
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NCBI chr 2:114,250,398...114,310,784
Ensembl chr 2:112,321,929...112,382,352
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G |
Prkcq |
protein kinase C, theta |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein] |
CTD |
PMID:16241859 |
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NCBI chr17:72,156,215...72,288,508
Ensembl chr17:67,246,394...67,378,704
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G |
Prkcz |
protein kinase C, zeta |
affects localization increases expression multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate affects the localization of PRKCZ protein Tetradecanoylphorbol Acetate results in increased expression of PRKCZ protein modified form Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of PRKCZ protein |
CTD |
PMID:12590138 PMID:15976015 PMID:16532021 |
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NCBI chr 5:171,101,774...171,212,694
Ensembl chr 5:165,819,466...165,930,367
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G |
Prkd1 |
protein kinase D1 |
multiple interactions increases phosphorylation affects localization increases expression affects phosphorylation |
ISO EXP |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKD1 protein]; [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] which results in increased expression of ATP7B protein; bisindolylmaleimide I affects the reaction [Tetradecanoylphorbol Acetate affects the phosphorylation of PRKD1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD1 protein] TPA affects localization of Prkd1 protein in cardiomyocytes PMA increases phosphorylation of Prkd1 protein in neonatal ventricular myocytes Tetradecanoylphorbol Acetate results in increased expression of PRKD1 protein modified form Tetradecanoylphorbol Acetate affects the localization of PRKD1 protein [Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein; Go 6976 inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PRKD1 protein] which affects the localization of HDAC5 protein]; PRKD1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of FOS protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of JUN protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CREB1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of PRKD1 protein |
CTD RGD |
PMID:9852137 PMID:15380616 PMID:16532021 PMID:19124542 PMID:21047949 PMID:21189263 PMID:21705328 PMID:37562720 PMID:15652511 PMID:16648482 More...
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RGD:288084581, RGD:243065275 |
NCBI chr 6:73,460,640...73,774,433
Ensembl chr 6:67,725,905...68,039,042
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G |
Prkd2 |
protein kinase D2 |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein]; kb-NB142-70 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PRKD2 protein] |
CTD |
PMID:24634417 PMID:37562720 |
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NCBI chr 1:86,640,095...86,670,476
Ensembl chr 1:77,513,986...77,542,376
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G |
Prl |
prolactin |
increases expression multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of PRL mRNA [Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]; Cyclosporine inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; Cyclosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] promotes the reaction [PRL protein results in increased activity of OTC protein]]; didemnins inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein]]; Tetradecanoylphorbol Acetate promotes the reaction [PRL protein results in increased activity of OTC protein] |
CTD |
PMID:3097147 PMID:21467749 |
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NCBI chr17:38,287,355...38,298,234
Ensembl chr17:37,860,007...37,870,062
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G |
Procr |
protein C receptor |
multiple interactions increases expression decreases cleavage affects localization |
ISO |
[Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which affects the localization of PROCR protein; [Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ADAM17 protein]] which results in decreased cleavage of and results in decreased secretion of PROCR protein; Methylthiouracil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PROCR protein modified form]; Rosmarinic Acid inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of PROCR protein]; Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of PROCR protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [ADAM17 protein results in increased cleavage of PROCR protein]] Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased cleavage of PROCR protein] |
CTD |
PMID:23774263 PMID:24632454 PMID:26298005 |
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NCBI chr 3:164,714,727...164,718,994
Ensembl chr 3:144,254,380...144,258,903
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G |
Prxl2b |
peroxiredoxin like 2B |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of PRXL2B mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:170,744,953...170,747,556
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G |
Psmb10 |
proteasome 20S subunit beta 10 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] |
CTD |
PMID:22398747 |
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NCBI chr19:50,740,808...50,743,292
Ensembl chr19:33,827,229...33,833,626
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G |
Psmb8 |
proteasome 20S subunit beta 8 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNG mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL10 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL4 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin] |
CTD |
PMID:22398747 |
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NCBI chr20:4,654,068...4,657,049
Ensembl chr20:4,652,159...4,655,283
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G |
Psmc2 |
proteasome 26S subunit, ATPase 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PSMC2 protein |
CTD |
PMID:16343552 |
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NCBI chr 4:14,148,080...14,162,390
Ensembl chr 4:13,255,856...13,270,185
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G |
Psmc6 |
proteasome 26S subunit, ATPase 6 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PSMC6 protein |
CTD |
PMID:16343552 |
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NCBI chr15:21,022,314...21,043,785
Ensembl chr15:18,542,563...18,564,055
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G |
Ptafr |
platelet-activating factor receptor |
multiple interactions increases phosphorylation |
EXP |
RGS4 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTAFR protein] |
CTD |
PMID:11297424 |
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NCBI chr 5:150,049,322...150,079,060
Ensembl chr 5:144,765,976...144,795,251
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G |
Ptger3 |
prostaglandin E receptor 3 |
multiple interactions increases phosphorylation |
EXP |
Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTGER3 protein alternative form] |
CTD |
PMID:15937517 |
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NCBI chr 2:249,264,985...249,409,966
Ensembl chr 2:246,606,183...246,684,434
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of PTGES mRNA |
CTD |
PMID:18922899 |
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NCBI chr 3:34,575,643...34,586,987
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G |
Ptgfr |
prostaglandin F receptor |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTGFR mRNA |
CTD |
PMID:23519560 |
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NCBI chr 2:243,390,820...243,426,647
Ensembl chr 2:240,733,375...240,765,650
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PTGS1; Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS1 protein] |
CTD |
PMID:10381133 PMID:12086399 |
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NCBI chr 3:39,981,419...40,002,993
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression increases activity |
ISO EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3-methylquercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Resveratrol co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone; [Ursolic Acid co-treated with Glucaric Acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; AHR protein affects the reaction [SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Anti-Inflammatory Agents inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; Capsaicin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; EGFR gene mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; gingerol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Glucaric Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; IL17RA gene mutant form inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Oleanolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]]; RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; SGA 360 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; shogaol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Tetradecanoylphorbol Acetate inhibits the reaction [helioxanthin inhibits the reaction [[Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased expression of PTGS2 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [taiwanin C results in decreased expression of PTGS2 protein]; Tetradecanoylphorbol Acetate promotes the reaction [PTGS2 protein results in increased chemical synthesis of Dinoprostone]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of PTGS2 protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; Ursolic Acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of PTGS2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] Tetradecanoylphorbol Acetate results in increased expression of PTGS2; Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein 1,5-bis(2-bromophenyl)penta-1,4-dien-3-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; 1,5-bis(2-bromophenyl)penta-1,4-dien-3-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2]; 3,4-dihydroxyphenylethanol inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein; [Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA; [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of 8-epi-prostaglandin F2alpha; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone; [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Thromboxane B2; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTGS2 mRNA; Apigenin affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; BAG1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; baicalein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; BAY 11-7085 inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; BAY 11-7085 inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; beta-ionone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; daidzein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Dithiothreitol inhibits the reaction [3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]]; Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Equol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTGS2 protein]; Gallic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein]; GW 1929 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; MAPK1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; MAPK3 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Peptides inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in decreased chemical synthesis of Dinoprostone]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Reactive Oxygen Species affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PTGS2 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein]; Rosiglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of PTGS2 protein; tricin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] [Genistein co-treated with Capsaicin] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; Genistein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; midostaurin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]; platycodin D inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] |
CTD |
PMID:8621535 PMID:8989914 PMID:9013627 PMID:9576062 PMID:9705326 PMID:10381133 PMID:10718345 PMID:10783318 PMID:11237475 PMID:11458457 PMID:12201673 PMID:12872987 PMID:14530214 PMID:14613874 PMID:15122579 PMID:15630167 PMID:15680906 PMID:15843042 PMID:15997105 PMID:16417216 PMID:16474181 PMID:16552572 PMID:16557482 PMID:16870006 PMID:16979875 PMID:17767925 PMID:17944529 PMID:18551458 PMID:18683823 PMID:18958680 PMID:19063610 PMID:19095747 PMID:19416633 PMID:19539808 PMID:19656660 PMID:19723084 PMID:19804834 PMID:20004183 PMID:20026373 PMID:20032081 PMID:20043298 PMID:20155627 PMID:20172950 PMID:20423157 PMID:20584749 PMID:20606309 PMID:20660715 PMID:20709134 PMID:20858459 PMID:21375462 PMID:21511917 PMID:21807015 PMID:22036979 PMID:22353212 PMID:22359662 PMID:22523472 PMID:22542552 PMID:22595400 PMID:22760862 PMID:22981962 PMID:22986104 PMID:23399806 PMID:23835587 PMID:23899529 PMID:24304388 PMID:24337631 PMID:24836925 PMID:25818598 PMID:26100520 PMID:26464283 PMID:26513295 PMID:26537528 PMID:27224899 PMID:28108223 PMID:28709031 PMID:29458014 PMID:31351099 PMID:31506784 PMID:32662567 More...
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NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188
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Pthlh |
parathyroid hormone-like hormone |
increases secretion |
EXP |
Tetradecanoylphorbol Acetate results in increased secretion of PTHLH protein |
CTD |
PMID:7946399 |
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NCBI chr 4:181,919,400...181,930,454
Ensembl chr 4:180,188,792...180,199,847
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G |
Ptk2 |
protein tyrosine kinase 2 |
multiple interactions increases expression increases phosphorylation |
ISO |
[oxophenylarsine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTK2 protein; [Tetradecanoylphorbol Acetate co-treated with oxotremorine M] results in increased phosphorylation of PTK2 protein; [Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein; [Vanadates co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTK2 protein; [Wortmannin co-treated with Tetradecanoylphorbol Acetate] inhibits the reaction [oxotremorine M results in increased phosphorylation of PTK2 protein]; Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTK2 protein]; Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein]]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTK2 protein]; oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Wortmannin] results in increased phosphorylation of PTK2 protein] |
CTD |
PMID:10537051 PMID:10569804 PMID:24211529 PMID:28527916 PMID:37562720 |
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NCBI chr 7:107,015,730...107,220,865
Ensembl chr 7:105,126,728...105,331,783
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G |
Ptk2b |
protein tyrosine kinase 2 beta |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of PTK2B protein |
CTD |
PMID:16877402 |
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NCBI chr15:44,536,275...44,656,754
Ensembl chr15:40,360,723...40,481,282
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G |
Ptn |
pleiotrophin |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of PTN mRNA |
CTD |
PMID:19840844 |
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NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:65,293,734...65,375,456
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G |
Ptprn2 |
protein tyrosine phosphatase, receptor type N2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTPRN2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:143,582,568...144,334,573
Ensembl chr 6:137,439,540...138,191,575
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of PTTG1 mRNA [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of PTTG1 mRNA |
CTD |
PMID:19031421 PMID:19840844 |
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NCBI chr10:28,394,940...28,406,410
Ensembl chr10:27,893,689...27,904,837
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G |
Ptx3 |
pentraxin 3 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of PTX3 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:152,797,563...152,803,372
Ensembl chr 2:150,487,513...150,493,323
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 mRNA; [Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of RAC1 protein; RAC1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein] Tetradecanoylphorbol Acetate results in increased expression of RAC1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of RAC1 protein; Tetradecanoylphorbol Acetate results in increased expression of RAC1 protein modified form |
CTD |
PMID:18922899 PMID:21705328 PMID:28527916 |
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NCBI chr12:16,150,411...16,170,864
Ensembl chr12:11,036,698...11,057,251
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Rac2 |
Rac family small GTPase 2 |
multiple interactions |
ISO |
RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; RAC2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:11145705 |
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NCBI chr 7:111,981,825...112,009,201
Ensembl chr 7:110,116,260...110,128,720
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G |
Rack1 |
receptor for activated C kinase 1 |
multiple interactions |
ISO |
1-Butanol affects the reaction [RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:12782152 |
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NCBI chr10:33,668,560...33,676,031
Ensembl chr10:33,169,169...33,174,975
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Rad21 |
RAD21 cohesin complex component |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RAD21 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:83,287,870...83,314,817
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Rad51ap1 |
RAD51 associated protein 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RAD51AP1 mRNA |
CTD |
PMID:19000923 PMID:19031421 |
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NCBI chr 4:161,445,610...161,458,661
Ensembl chr 4:159,759,459...159,772,524
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Rad51c |
RAD51 paralog C |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RAD51C mRNA |
CTD |
PMID:19031421 |
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NCBI chr10:72,702,299...72,728,980
Ensembl chr10:72,205,032...72,231,248
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G |
Rad54l |
RAD54 like |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RAD54L mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:134,812,158...134,841,821
Ensembl chr 5:129,575,378...129,605,070
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions increases expression increases activity |
ISO |
[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; cypermethrin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; dephostatin promotes the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RAF1 protein]; Okadaic Acid inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein]; perillyl alcohol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RAF1 protein]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of RAF1 protein]; tautomycin inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased activity of RAF1 protein] |
CTD |
PMID:14623285 PMID:19161993 PMID:22760862 |
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NCBI chr 4:150,352,158...150,412,813
Ensembl chr 4:148,679,530...148,740,317
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Rara |
retinoic acid receptor, alpha |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with salvin] results in increased expression of RARA protein |
CTD |
PMID:11504768 |
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NCBI chr10:84,379,780...84,424,371
Ensembl chr10:83,893,384...83,928,142
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G |
Rarres1 |
retinoic acid receptor responder 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RARRES1 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 2:154,059,761...154,094,021
Ensembl chr 2:151,749,715...151,783,978
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G |
Rasal3 |
RAS protein activator like 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RASAL3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 7:12,047,090...12,061,883
Ensembl chr 7:11,396,090...11,411,465
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G |
Rassf2 |
Ras association domain family member 2 |
decreases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased methylation of RASSF2 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased methylation of RASSF2 gene] |
CTD |
PMID:32135139 |
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NCBI chr 3:139,697,187...139,733,402
Ensembl chr 3:119,245,821...119,280,431
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Rb1 |
RB transcriptional corepressor 1 |
multiple interactions increases phosphorylation increases expression decreases phosphorylation |
ISO |
4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RB1 mRNA; IL2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]; Ro 41-5253 inhibits the reaction [Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein]]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RB1 protein] Tetradecanoylphorbol Acetate results in increased expression of RB1 protein modified form Tetradecanoylphorbol Acetate results in decreased phosphorylation of RB1 protein |
CTD |
PMID:8927716 PMID:9348195 PMID:12421932 PMID:15978937 PMID:16979875 |
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NCBI chr15:54,780,858...54,911,989
Ensembl chr15:48,371,296...48,502,302
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Rbbp8 |
RB binding protein 8, endonuclease |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RBBP8 mRNA |
CTD |
PMID:19031421 |
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NCBI chr18:3,198,188...3,263,643
Ensembl chr18:2,921,286...2,988,846
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G |
Rbfox2 |
RNA binding fox-1 homolog 2 |
increases expression |
ISO |
PMA increases expression of RBFOX2 mRNA in monocytes |
RGD |
PMID:29771377 |
RGD:329849002 |
NCBI chr 7:110,691,230...110,934,901
Ensembl chr 7:108,810,628...109,054,691
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Rbpj |
recombination signal binding protein for immunoglobulin kappa J region |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of RBPJ protein |
CTD |
PMID:23134680 |
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NCBI chr14:61,551,366...61,736,220
Ensembl chr14:57,338,507...57,523,353
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G |
Rbx1 |
ring-box 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RBX1 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 7:114,870,893...114,881,194
Ensembl chr 7:112,990,835...113,001,051
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Rel |
REL proto-oncogene, NF-kB subunit |
multiple interactions affects localization |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of REL mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of REL protein] |
CTD |
PMID:9122163 PMID:15477007 PMID:16376386 |
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NCBI chr14:101,891,238...101,922,324
Ensembl chr14:97,695,161...97,720,892
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Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases phosphorylation increases expression increases localization increases activity affects localization |
ISO EXP |
3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein]; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein; Chlorogenic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased expression of RELA protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; honokiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Hydrolyzable Tannins inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of RELA protein]; Lipopolysaccharides analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]; protocatechuic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein 1'-acetoxychavicol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; 3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; [Arsenic Trioxide co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of and results in increased localization of RELA protein; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of RELA protein; [epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; [Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased activity of and results in increased localization of RELA protein; [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein; Anethole Trithione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Apigenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein]; artenimol inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of RELA protein]; BAG1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased degradation of NFKBIA protein] which results in increased localization of and results in increased activity of RELA protein]; Bee Venoms inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Catechin analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] affects the localization of RELA protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein]; epicatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; epigallocatechin gallate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; evodiamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Fenretinide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Gliotoxin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein]; indole-3-carbinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; kahweol acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; lonafarnib inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Luteolin analog inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; Melitten inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of RELA protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; piperine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein]; platyconic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; pregna-4,17-diene-3,16-dione inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pyrazolanthrone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; RELA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of RELA protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of RELA protein]; scoparone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; shogaol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate affects the localization of and results in increased phosphorylation of RELA protein; Tetradecanoylphorbol Acetate inhibits the reaction [teriflunomide results in increased activity of [NFKB1 protein binds to RELA protein]]; Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]; Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of RELA protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased localization of and results in increased activity of RELA protein; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of RELA protein; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RELA protein]; zerumbone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]] Tetradecanoylphorbol Acetate results in increased expression of RELA protein; Tetradecanoylphorbol Acetate results in increased expression of RELA protein modified form resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein] |
CTD |
PMID:8573121 PMID:9973483 PMID:10692565 PMID:14527959 PMID:15090542 PMID:15322087 PMID:15710601 PMID:15811958 PMID:15905586 PMID:16007145 PMID:16174796 PMID:16230421 PMID:16376386 PMID:16474181 PMID:16928326 PMID:17498959 PMID:17588137 PMID:17767925 PMID:17984113 PMID:18551458 PMID:18958421 PMID:19284563 PMID:19375915 PMID:19416633 PMID:19539808 PMID:19665545 PMID:19969058 PMID:20026373 PMID:20043298 PMID:20082219 PMID:20152819 PMID:20155627 PMID:20206692 PMID:20438634 PMID:20590612 PMID:20709134 PMID:20858459 PMID:21354279 PMID:21375462 PMID:21515303 PMID:22213337 PMID:22322153 PMID:22542552 PMID:22595400 PMID:22634262 PMID:22981962 PMID:23399806 PMID:23535185 PMID:23899529 PMID:25446327 PMID:25540590 PMID:25590691 PMID:25656647 PMID:25818598 PMID:26187476 PMID:26220752 PMID:26614570 PMID:28108223 PMID:30133131 PMID:30590137 PMID:31068361 PMID:31351099 PMID:34626302 PMID:36075570 More...
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NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484
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G |
Resp18 |
regulated endocrine-specific protein 18 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RESP18 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 9:84,213,844...84,220,186
Ensembl chr 9:76,764,590...76,778,722
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G |
Rfc4 |
replication factor C subunit 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RFC4 mRNA |
CTD |
PMID:19031421 |
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NCBI chr11:91,254,273...91,268,727
Ensembl chr11:77,749,638...77,764,122
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G |
Rfc5 |
replication factor C subunit 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RFC5 mRNA |
CTD |
PMID:19031421 |
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NCBI chr12:44,868,322...44,877,879
Ensembl chr12:39,207,484...39,217,312
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G |
Rgcc |
regulator of cell cycle |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGCC mRNA [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RGCC mRNA |
CTD |
PMID:16979875 PMID:31904401 |
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NCBI chr15:61,071,574...61,084,408
Ensembl chr15:54,662,483...54,681,141
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G |
Rgs11 |
regulator of G-protein signaling 11 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGS11 mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:15,727,279...15,735,536
Ensembl chr10:15,222,803...15,231,060
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G |
Rgs13 |
regulator of G-protein signaling 13 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of RGS13 mRNA |
CTD |
PMID:16979875 |
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NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648
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G |
Rgs16 |
regulator of G-protein signaling 16 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RGS16 mRNA |
CTD |
PMID:31068361 |
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NCBI chr13:68,421,480...68,443,312
Ensembl chr13:65,887,530...65,892,857
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G |
Rgs4 |
regulator of G-protein signaling 4 |
multiple interactions |
EXP |
RGS4 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of PTAFR protein] |
CTD |
PMID:11297424 |
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NCBI chr13:84,469,593...84,475,884
Ensembl chr13:81,936,775...81,943,068
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G |
Rhbdf2 |
rhomboid 5 homolog 2 |
multiple interactions |
ISO |
RHBDF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of HBEGF protein] |
CTD |
PMID:28703301 |
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NCBI chr10:102,331,991...102,359,117
Ensembl chr10:101,833,157...101,860,283
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G |
Rhog |
ras homolog family member G |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:166,030,685...166,046,254
Ensembl chr 1:156,615,349...156,631,257
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G |
Rif1 |
replication timing regulatory factor 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RIF1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 3:56,963,840...57,017,106
Ensembl chr 3:36,554,697...36,603,617
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G |
Rnaset2 |
ribonuclease T2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:55,133,532...55,150,701
Ensembl chr 1:52,585,929...52,603,147
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G |
Rnf187 |
ring finger protein 187 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein TRIM7 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein] |
CTD |
PMID:25851810 |
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NCBI chr10:44,209,080...44,214,979
Ensembl chr10:43,702,357...43,716,157
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G |
Rnf4 |
ring finger protein 4 |
multiple interactions |
EXP |
[Tetradecanoylphorbol Acetate co-treated with Colforsin] results in increased expression of RNF4 mRNA |
CTD |
PMID:14749358 |
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NCBI chr14:80,625,864...80,647,138
Ensembl chr14:76,401,299...76,422,566
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G |
Rock1 |
Rho-associated coiled-coil containing protein kinase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ROCK1 protein |
CTD |
PMID:24760326 |
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NCBI chr18:1,387,360...1,509,218
Ensembl chr18:1,115,905...1,235,571
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G |
Rpe65 |
retinoid isomerohydrolase RPE65 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RPE65 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 2:251,425,228...251,457,209
Ensembl chr 2:248,766,612...248,798,403
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G |
Rpl7 |
ribosomal protein L7 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPL7 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:8,000,446...8,003,454
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G |
Rps11 |
ribosomal protein S11 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS11 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 1:104,742,153...104,744,261
Ensembl chr 1:95,605,692...95,607,874
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G |
Rps20 |
ribosomal protein S20 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of RPS20 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 5:21,616,687...21,618,068
Ensembl chr 5:16,819,304...16,820,475 Ensembl chr 9:16,819,304...16,820,475 Ensembl chr 3:16,819,304...16,820,475 Ensembl chr 5:16,819,304...16,820,475
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G |
Rps6 |
ribosomal protein S6 |
multiple interactions increases phosphorylation |
ISO |
[Tetradecanoylphorbol Acetate results in increased activity of PRKCH protein] inhibits the reaction [Sirolimus results in decreased phosphorylation of RPS6 protein] Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein Plant Extracts inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6 protein] |
CTD |
PMID:16832347 PMID:18245498 |
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NCBI chr 5:106,417,680...106,420,540
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6ka1 |
ribosomal protein S6 kinase A1 |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein] |
CTD |
PMID:17693661 |
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NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:146,079,021...146,118,272
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions increases phosphorylation |
ISO |
SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]]; Sodium Salicylate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein Benzofurans analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:10993886 PMID:30696844 |
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NCBI chr10:71,817,794...71,865,211
Ensembl chr10:71,323,777...71,367,908
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G |
Rspo3 |
R-spondin 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RSPO3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 1:30,112,529...30,197,267
Ensembl chr 1:28,283,914...28,367,061
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G |
RT1-Da |
RT1 class II, locus Da |
multiple interactions |
EXP |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RT1-DA protein |
CTD |
PMID:9536116 |
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NCBI chr20:4,515,393...4,520,387
Ensembl chr20:4,512,911...4,518,455
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G |
RT1-DMb |
RT1 class II, locus DMb |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of H2-DMB1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr20:4,695,009...4,702,560
Ensembl chr20:4,693,103...4,700,340
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G |
Rtp4 |
receptor (chemosensory) transporter protein 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of RTP4 mRNA |
CTD |
PMID:31904401 |
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NCBI chr11:90,741,992...90,840,061
Ensembl chr11:77,238,216...77,335,437
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G |
Runx2 |
RUNX family transcription factor 2 |
multiple interactions increases expression |
ISO |
CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RUNX2 protein] |
CTD |
PMID:37562720 |
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NCBI chr 9:23,661,278...23,990,248
Ensembl chr 9:16,167,482...16,492,167
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G |
Rxra |
retinoid X receptor alpha |
decreases degradation decreases localization multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein Tetradecanoylphorbol Acetate results in decreased localization of RXRA protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased degradation of RXRA protein] |
CTD |
PMID:12970875 |
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NCBI chr 3:31,387,892...31,474,415
Ensembl chr 3:10,989,832...11,073,712
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G |
S100a4 |
S100 calcium-binding protein A4 |
multiple interactions increases expression |
ISO |
Atrazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A4 mRNA] |
CTD |
PMID:24211529 |
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NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:176,091,804...176,093,254
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G |
S100a6 |
S100 calcium binding protein A6 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of S100A6 protein |
CTD |
PMID:20045496 PMID:24073338 |
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NCBI chr 2:178,398,189...178,399,763
Ensembl chr 2:176,100,899...176,102,180
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G |
S100a8 |
S100 calcium binding protein A8 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA] Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA; Tetradecanoylphorbol Acetate results in increased expression of S100A8 protein |
CTD |
PMID:1733233 PMID:20172950 PMID:22359662 |
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NCBI chr 2:178,464,095...178,465,223
Ensembl chr 2:176,167,124...176,167,643
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G |
S100a9 |
S100 calcium binding protein A9 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; IL17RA gene mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA] |
CTD |
PMID:1733233 PMID:20045496 PMID:20172950 PMID:22359662 PMID:24073338 |
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NCBI chr 2:178,487,941...178,490,622
Ensembl chr 2:176,190,361...176,193,230
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G |
S100b |
S100 calcium binding protein B |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of AGER protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [Trientine inhibits the reaction [S100B protein results in increased expression of BACE1 protein]] |
CTD |
PMID:23541064 |
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NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,881...12,394,743
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G |
Sart1 |
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:212,119,824...212,128,517
Ensembl chr 1:202,690,459...202,699,136
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
[2-acetyltributylcitrate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SCD1 mRNA |
CTD |
PMID:37055963 |
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NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562
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G |
Scly |
selenocysteine lyase |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SCLY protein |
CTD |
PMID:30218697 |
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NCBI chr 9:99,337,796...99,358,487
Ensembl chr 9:91,890,306...91,910,941
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G |
Scrn1 |
secernin 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SCRN1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 4:84,962,450...85,024,577
Ensembl chr 4:83,632,131...83,693,852
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G |
Sdc1 |
syndecan 1 |
multiple interactions increases secretion decreases expression |
ISO |
GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC1 protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC1 protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased cleavage of and results in increased secretion of SDC1 protein Tetradecanoylphorbol Acetate results in decreased expression of SDC1 protein alternative form |
CTD |
PMID:19875451 PMID:26852939 |
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NCBI chr 6:37,282,041...37,304,503
Ensembl chr 6:31,562,739...31,585,264
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G |
Sdc4 |
syndecan 4 |
multiple interactions decreases expression |
ISO |
GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC4 protein]; N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SDC4 protein]; Tetradecanoylphorbol Acetate affects the localization of and results in increased cleavage of and results in increased secretion of SDC4 protein Tetradecanoylphorbol Acetate results in decreased expression of SDC4 protein alternative form |
CTD |
PMID:19875451 |
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NCBI chr 3:173,574,239...173,592,923
Ensembl chr 3:153,154,896...153,173,580
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G |
Sec61g |
Sec61 translocon subunit gamma |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SEC61G mRNA |
CTD |
PMID:19840844 |
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NCBI chr14:95,113,083...95,119,458
Ensembl chr14:90,899,768...90,906,162 Ensembl chr 9:90,899,768...90,906,162
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G |
Sele |
selectin E |
multiple interactions increases expression |
ISO |
[Colforsin co-treated with Rolipram] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein]; adenosine-3',5'-cyclic phosphorothioate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SELE protein] |
CTD |
PMID:8780174 |
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NCBI chr13:78,935,997...78,945,905
Ensembl chr13:76,403,304...76,412,741
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G |
Selenop |
selenoprotein P |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SELENOP mRNA |
CTD |
PMID:19840844 |
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NCBI chr 2:54,225,736...54,236,022
Ensembl chr 2:52,498,339...52,508,852
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G |
Selenos |
selenoprotein S |
multiple interactions |
ISO |
SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein] |
CTD |
PMID:16227999 |
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NCBI chr 1:129,070,240...129,080,007
Ensembl chr 1:119,659,751...119,669,833
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G |
Sell |
selectin L |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of SELL mRNA; fulvic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of SELL mRNA] |
CTD |
PMID:21331654 |
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NCBI chr13:78,950,100...78,969,604
Ensembl chr13:76,416,915...76,436,456
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G |
Sem1 |
SEM1 26S proteasome subunit |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SEM1 mRNA [Tetradecanoylphorbol Acetate co-treated with arsenic trioxide] results in increased expression of SEM1 mRNA |
CTD |
PMID:18922899 |
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NCBI chr 4:35,638,306...35,658,462
Ensembl chr 4:34,671,848...34,692,005
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G |
Serpinb2 |
serpin family B member 2 |
affects expression increases expression affects response to substance |
ISO |
Tetradecanoylphorbol Acetate affects the expression of SERPINB2 Tetradecanoylphorbol Acetate results in increased expression of SERPINB2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SERPINB2 protein SERPINB2 affects the susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:8631129 PMID:16044405 PMID:19945525 |
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NCBI chr13:24,051,933...24,065,032
Ensembl chr13:23,541,400...23,550,408
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G |
Serpinb9 |
serpin family B member 9 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SERPINB9 protein |
CTD |
PMID:12177049 |
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NCBI chr17:31,628,887...31,652,003
Ensembl chr17:31,420,125...31,443,230
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions increases secretion increases expression |
ISO EXP |
[sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 protein Tetradecanoylphorbol Acetate results in increased secretion of SERPINE1 protein Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA] [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA; [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of SERPINE1 protein |
CTD |
PMID:12409145 PMID:16368122 PMID:18958680 PMID:35001170 |
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NCBI chr12:25,237,977...25,248,356
Ensembl chr12:19,601,272...19,611,657
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G |
Sf3b4 |
splicing factor 3B subunit 4 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:186,421,667...186,426,419
Ensembl chr 2:183,732,754...183,737,959
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G |
Sfrp1 |
secreted frizzled-related protein 1 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP1 mRNA |
CTD |
PMID:23519560 |
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NCBI chr16:75,278,325...75,316,736
Ensembl chr16:68,575,763...68,614,286
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFRP2 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SFRP2 mRNA |
CTD |
PMID:23519560 PMID:31904401 |
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NCBI chr 2:171,387,536...171,395,081
Ensembl chr 2:169,089,517...169,097,063
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G |
Sftpb |
surfactant protein B |
increases secretion multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased secretion of SFTPB protein Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPB protein] |
CTD |
PMID:11704537 PMID:14565945 |
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NCBI chr 4:105,917,495...105,926,631
Ensembl chr 4:104,359,396...104,368,436
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G |
Sftpc |
surfactant protein C |
increases secretion multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased secretion of SFTPC protein Ro 31-8220 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of SFTPC protein] |
CTD |
PMID:11704537 PMID:14565945 |
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NCBI chr15:52,006,274...52,009,324
Ensembl chr15:45,596,574...45,610,777
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G |
Sftpd |
surfactant protein D |
multiple interactions |
EXP ISO |
[Terbutaline co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SFTPD protein [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SFTPD mRNA |
CTD |
PMID:9476903 PMID:23519560 |
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NCBI chr16:17,080,575...17,093,047
Ensembl chr16:17,046,483...17,059,927
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G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
multiple interactions increases expression |
EXP ISO |
Tetradecanoylphorbol Acetate promotes the reaction [11-dehydrocorticosterone results in increased expression of SGK1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cortisone results in increased expression of SGK1 mRNA] Tetradecanoylphorbol Acetate results in increased expression of SGK1 mRNA |
CTD |
PMID:16533503 PMID:31068361 |
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NCBI chr 1:24,799,391...24,916,886
Ensembl chr 1:22,980,261...23,098,283
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G |
Shank2 |
SH3 and multiple ankyrin repeat domains 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SHANK2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:208,575,144...209,020,300
Ensembl chr 1:199,169,429...199,589,394
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G |
Shc1 |
SHC adaptor protein 1 |
increases expression increases phosphorylation multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in increased expression of SHC1 mRNA Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form]; Tetradecanoylphorbol Acetate inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SHC1 protein alternative form] |
CTD |
PMID:19031421 PMID:19168439 |
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NCBI chr 2:177,135,649...177,147,257
Ensembl chr 2:174,837,930...174,849,536
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G |
Siglec5 |
sialic acid binding Ig-like lectin 5 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SIGLEC6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:102,904,705...102,913,281
Ensembl chr 1:93,768,319...93,776,694
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G |
Sla |
src-like adaptor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:100,423,467...100,473,840
Ensembl chr 7:98,535,368...98,584,648
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G |
Slc17a3 |
solute carrier family 17 member 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLC17A3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr17:41,698,679...41,729,057
Ensembl chr17:41,270,812...41,295,256
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G |
Slc19a1 |
solute carrier family 19 member 1 |
multiple interactions decreases activity |
EXP |
bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]]; Tetradecanoylphorbol Acetate inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate] Tetradecanoylphorbol Acetate results in decreased activity of SLC19A1 protein |
CTD |
PMID:17482559 |
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NCBI chr20:11,583,928...11,601,959
Ensembl chr20:11,584,411...11,601,972
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G |
Slc1a1 |
solute carrier family 1 member 1 |
multiple interactions increases activity |
EXP |
[Tetradecanoylphorbol Acetate co-treated with Propofol] inhibits the reaction [tert-Butylhydroperoxide results in decreased activity of SLC1A1 protein]; Caffeine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SLC1A1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [Nicotine results in decreased activity of SLC1A1 protein] |
CTD |
PMID:17382927 PMID:23262392 PMID:23602688 PMID:24355585 |
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NCBI chr 1:235,963,455...236,043,572
Ensembl chr 1:226,549,842...226,630,402
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G |
Slc1a2 |
solute carrier family 1 member 2 |
multiple interactions |
EXP |
[phorbol 13-acetate 12-myristate cotreatment with morphine] decreases expression of GLT-1 protein in cultured astrocytes |
RGD |
PMID:28341892 |
RGD:597978120 |
NCBI chr 3:109,460,109...109,590,445
Ensembl chr 3:89,005,129...89,126,498
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G |
Slc1a5 |
solute carrier family 1 member 5 |
decreases expression |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of SLC1A5 protein |
CTD |
PMID:21812036 |
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NCBI chr 1:86,584,949...86,599,052
Ensembl chr 1:77,456,694...77,470,952
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G |
Slc2a1 |
solute carrier family 2 member 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SLC2A1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc35f1 |
solute carrier family 35, member F1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLC35F1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr20:32,573,091...32,961,466
Ensembl chr20:32,030,368...32,418,611
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G |
Slc38a3 |
solute carrier family 38, member 3 |
decreases expression |
EXP |
Tetradecanoylphorbol Acetate results in decreased expression of SLC38A3 protein |
CTD |
PMID:21812036 |
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NCBI chr 8:117,202,534...117,220,310
Ensembl chr 8:108,323,894...108,339,988
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G |
Slc3a2 |
solute carrier family 3 member 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:215,033,601...215,048,064
Ensembl chr 1:205,604,468...205,618,931
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G |
Slc5a6 |
solute carrier family 5 member 6 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [SLC5A6 protein results in increased transport of Biotin] |
CTD |
PMID:15561972 |
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NCBI chr 6:31,039,865...31,051,671
Ensembl chr 6:25,320,442...25,331,712
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G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SLC6A3 protein; Tetradecanoylphorbol Acetate results in increased localization of [SLC6A3 protein co-treated with EEA1 protein] |
CTD |
PMID:22683840 PMID:24101030 |
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NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413
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G |
Slc6a4 |
solute carrier family 6 member 4 |
multiple interactions decreases activity increases phosphorylation |
EXP |
TPA decreases activity of Slc6a4 protein in synaptosomes, TPA increases phosphorylation of Slc6a4 protein in synaptosomes TPA decreases activity of Slc6a4 protein in cultured neurons |
RGD |
PMID:11113454 PMID:11859926 PMID:12590935 |
RGD:38456013, RGD:38549589, RGD:38549585 |
NCBI chr10:62,322,688...62,357,060
Ensembl chr10:61,826,123...61,858,384
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G |
Slc7a11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SLC7A11 mRNA |
CTD |
PMID:17200146 PMID:26198647 |
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NCBI chr 2:136,532,912...136,668,560
Ensembl chr 2:133,963,107...134,517,536
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G |
Slc8a1 |
solute carrier family 8 member A1 |
multiple interactions |
EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Thapsigargin results in increased expression of SLC8A1 mRNA] |
CTD |
PMID:19244478 |
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NCBI chr 6:18,975,498...19,299,704
Ensembl chr 6:13,194,662...13,535,628
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G |
Slit3 |
slit guidance ligand 3 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SLIT3 mRNA |
CTD |
PMID:31904401 |
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NCBI chr10:20,075,929...20,660,704
Ensembl chr10:19,571,684...20,156,634
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G |
Smad2 |
SMAD family member 2 |
multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein; Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SMAD2 protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate affects the localization of SMAD2 protein modified form] |
CTD |
PMID:20172950 |
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NCBI chr18:72,124,792...72,193,345
Ensembl chr18:69,850,377...69,912,323
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G |
Smad3 |
SMAD family member 3 |
multiple interactions increases methylation |
ISO |
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of SMAD3 gene] |
CTD |
PMID:32135139 |
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NCBI chr 8:73,022,204...73,132,324
Ensembl chr 8:64,110,039...64,236,960
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G |
Smc4 |
structural maintenance of chromosomes 4 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SMC4 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 2:155,550,262...155,578,695
Ensembl chr 2:153,240,283...153,271,571
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G |
Smpd1 |
sphingomyelin phosphodiesterase 1 |
multiple interactions |
ISO |
SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased stability of IL6 mRNA]; SMPD1 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 protein] |
CTD |
PMID:24951586 |
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NCBI chr 1:169,304,772...169,308,615
Ensembl chr 1:159,892,859...159,896,794
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G |
Smpdl3a |
sphingomyelin phosphodiesterase, acid-like 3A |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SMPDL3A mRNA |
CTD |
PMID:31904401 |
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NCBI chr20:37,679,004...37,701,979
Ensembl chr20:37,132,592...37,155,567
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G |
Snai1 |
snail family transcriptional repressor 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; antroquinonol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SNAI1 protein] |
CTD |
PMID:25656647 |
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NCBI chr 3:176,667,476...176,671,965
Ensembl chr 3:156,248,485...156,252,969
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G |
Snora33 |
small nucleolar RNA, H/ACA box 33 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SNORA33 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 1:21,682,603...21,682,729
Ensembl chr10:87,188,831...87,188,962
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G |
Snora73b |
small nucleolar RNA, H/ACA box 73b |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SNORA73B mRNA |
CTD |
PMID:31068361 |
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NCBI chr 5:144,545,179...144,545,382
Ensembl chr 5:144,545,179...144,545,382
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G |
Snord51 |
small nucleolar RNA, C/D box 51 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SNORD51 mRNA |
CTD |
PMID:31068361 |
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NCBI chr 9:64,581,731...64,581,808
Ensembl chr 9:64,581,731...64,581,808
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G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SOCS2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 7:31,890,564...31,932,092
Ensembl chr 7:30,008,578...30,043,548
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions increases expression |
ISO |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOCS3 protein] |
CTD |
PMID:23782265 |
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NCBI chr10:103,692,579...103,695,975
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions decreases expression increases expression |
ISO |
Tetradecanoylphorbol Acetate promotes the reaction [Glucose deficiency results in decreased expression of and results in increased degradation of SOD1 protein] [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SOD1 protein Tetradecanoylphorbol Acetate results in decreased expression of SOD1 protein Tetradecanoylphorbol Acetate results in increased expression of SOD1 protein |
CTD |
PMID:17309078 PMID:20045496 PMID:20831825 PMID:24073338 PMID:31351099 |
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NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions increases expression increases activity increases abundance |
ISO EXP |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOD2 mRNA; [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] which results in increased expression of SOD2; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; CYBA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; Cycloheximide promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; FOXO3 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NCF2 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; NOXO1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; PRKCA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCB protein alternative form affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; RAC1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; rottlerin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of SOD2 protein]; SN50 peptide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCR1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1A mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R1 mRNA]; SOD2 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL1R2 mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with Ionomycin]; Tetradecanoylphorbol Acetate inhibits the reaction [12-deoxyphorbolphenylacetate-20-acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [SOD2 protein results in decreased expression of IL1A mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [thymeleatoxin results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [[SP1 protein binds to SOD2 promoter] which results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Cycloheximide results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate results in increased activity of and results in increased expression of SOD2 protein; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of SOD2 protein]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA] [decursin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SOD2 protein; SOD2 protein inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased abundance of 4-hydroxy-2-nonenal]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCE protein]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA]; SOD2 protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of JUN mRNA]; SOD2 protein results in decreased susceptibility to [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] [Tetradecanoylphorbol Acetate results in increased expression of TNF] which results in increased expression of SOD2; Tetradecanoylphorbol Acetate results in increased expression of SOD2 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SOD2 protein [Tetradecanoylphorbol Acetate results in increased abundance of Reactive Oxygen Species] which results in increased abundance of SOD2 |
CTD |
PMID:7564102 PMID:8037686 PMID:8702551 PMID:9067545 PMID:9434740 PMID:9756418 PMID:9837861 PMID:9852137 PMID:10601319 PMID:10669635 PMID:10769695 PMID:11507057 PMID:12161520 PMID:15330761 PMID:17309078 PMID:18958680 PMID:20831825 PMID:21045076 PMID:21705328 PMID:22429591 PMID:31351099 More...
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NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189
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G |
Sorl1 |
sortilin related receptor 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SORL1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:51,238,713...51,401,458
Ensembl chr 8:42,341,704...42,504,513
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G |
Sox17 |
SRY-box transcription factor 17 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of SOX17 mRNA |
CTD |
PMID:23519560 |
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NCBI chr 5:19,814,345...19,819,859
Ensembl chr 5:15,016,731...15,022,228
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G |
Sp1 |
Sp1 transcription factor |
multiple interactions increases expression increases activity |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of SP1 protein; Tetradecanoylphorbol Acetate promotes the reaction [[SP1 protein binds to SOD2 promoter] which results in increased expression of SOD2 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [SP1 protein binds to CDKN1A promoter] Tetradecanoylphorbol Acetate results in increased expression of SP1 mRNA Tetradecanoylphorbol Acetate results in increased activity of SP1 protein |
CTD |
PMID:10669635 PMID:15978937 PMID:24244623 PMID:27351882 |
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NCBI chr 7:135,419,864...135,450,513
Ensembl chr 7:133,541,491...133,571,961
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G |
Sp110 |
SP110 nuclear body protein |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SP110 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 9:93,648,574...93,673,476
Ensembl chr 9:86,200,503...86,222,670
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G |
Spag5 |
sperm associated antigen 5 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SPAG5 mRNA |
CTD |
PMID:19031421 |
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NCBI chr10:63,693,300...63,714,813
Ensembl chr10:63,198,768...63,216,745
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G |
Spi1 |
Spi-1 proto-oncogene |
increases activity |
ISO |
Tetradecanoylphorbol Acetate results in increased activity of SPI1 protein |
CTD |
PMID:18418899 |
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NCBI chr 3:97,529,509...97,548,204
Ensembl chr 3:77,073,012...77,092,393
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions increases expression |
ISO |
[FOS protein co-treated with JUN protein] inhibits the reaction [pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]]; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of SPP1 mRNA; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; CRT 0066101 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]; pirinixic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein]; PPARA protein affects the reaction [Bezafibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [fenofibric acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; PPARA protein affects the reaction [GW 9578 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [[FOS protein binds to JUN protein modified form] which binds to SPP1 promoter]; Troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA] [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SPP1 mRNA; [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of SPP1 mRNA Tetradecanoylphorbol Acetate results in increased expression of SPP1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of SPP1 protein |
CTD |
PMID:11426586 PMID:16979875 PMID:17360982 PMID:19840844 PMID:31904401 PMID:37562720 More...
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NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162
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G |
Sprr1a |
small proline-rich protein 1A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SPRR1A mRNA Tetradecanoylphorbol Acetate results in increased expression of SPRR1A mRNA; Tetradecanoylphorbol Acetate results in increased expression of SPRR1A protein |
CTD |
PMID:8617999 PMID:10866668 PMID:11485391 |
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NCBI chr 2:180,750,709...180,752,625
Ensembl chr 2:178,055,096...178,057,063
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G |
Sprr1b |
small proline-rich protein 1B |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SPRR1B mRNA |
CTD |
PMID:11485391 |
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NCBI chr 2:180,704,457...180,706,355
Ensembl chr 2:178,009,130...178,009,567
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G |
Sprr2a |
small proline rich protein 2A |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Arsenic Trioxide] results in increased expression of SPRR2A mRNA corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SPRR2H mRNA] |
CTD |
PMID:18922899 PMID:32135139 |
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NCBI chr 2:180,511,568...180,511,840
Ensembl chr 2:177,815,964...177,816,236
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G |
Sqstm1 |
sequestosome 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of SQSTM1 mRNA |
CTD |
PMID:26198647 |
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NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673
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G |
Src |
SRC proto-oncogene, non-receptor tyrosine kinase |
multiple interactions increases phosphorylation increases expression |
ISO |
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]]; SRC mutant form inhibits the reaction [Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]]; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SRC]] AG 1879 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of SRC protein] |
CTD |
PMID:20660715 PMID:26100520 PMID:26513295 PMID:28527916 PMID:34144024 |
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NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:146,091,841...146,139,476
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G |
Srebf2 |
sterol regulatory element binding transcription factor 2 |
increases cleavage multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein dorsomorphin promotes the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein]; Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein] |
CTD |
PMID:29499335 |
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NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:113,663,202...113,720,848
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G |
Srpra |
SRP receptor subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:41,818,199...41,824,292
Ensembl chr 8:33,560,348...33,566,470
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G |
Star |
steroidogenic acute regulatory protein |
multiple interactions increases expression |
ISO |
[Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]] promotes the reaction [CREBBP protein binds to STAR promoter]; [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone; [Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; CREBBP protein promotes the reaction [CREB1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; GFX 109203x inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; NR0B1 protein inhibits the reaction [[Tetradecanoylphorbol Acetate results in increased expression of STAR protein] which results in increased abundance of Progesterone]; NR0B1 protein inhibits the reaction [NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR0B1 protein inhibits the reaction [NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]]; NR4A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; NR5A1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKCD protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKCD protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; PRKCE protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKCE protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [[Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA]; PRKD1 protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate inhibits the reaction [NR0B1 protein binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [[Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein] which results in increased abundance of Progesterone]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine promotes the reaction [CREB1 protein modified form binds to STAR promoter]]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of and results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased expression of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]; Tetradecanoylphorbol Acetate promotes the reaction [CREB1 protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [CREBBP protein binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [FOS protein modified form binds to STAR promoter]; Tetradecanoylphorbol Acetate promotes the reaction [JUN protein modified form binds to STAR promoter]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Bucladesine results in increased phosphorylation of STAR protein]]; U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAR protein] Tetradecanoylphorbol Acetate results in increased expression of STAR mRNA; Tetradecanoylphorbol Acetate results in increased expression of STAR protein |
CTD |
PMID:18755854 PMID:18787026 PMID:19282384 PMID:21047949 |
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NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672
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G |
Stat3 |
signal transducer and activator of transcription 3 |
increases phosphorylation affects localization multiple interactions increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein Tetradecanoylphorbol Acetate affects the localization of STAT3 protein [Tetradecanoylphorbol Acetate co-treated with bisphenol A] results in decreased phosphorylation of STAT3 protein; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein] Tetradecanoylphorbol Acetate results in increased expression of STAT3 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT3 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]; Resveratrol promotes the reaction [Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]]; Tetradecanoylphorbol Acetate promotes the reaction [PRKCE protein binds to STAT3 protein]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the localization of STAT3 protein; Ursolic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]; Ursolic Acid promotes the reaction [Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STAT3]] |
CTD |
PMID:20523355 PMID:22986104 PMID:24496235 PMID:25128825 PMID:26100520 PMID:26513295 PMID:30133131 More...
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NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057
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G |
Stat5a |
signal transducer and activator of transcription 5A |
increases phosphorylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein CYBA protein promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein]; diphenyleneiodonium inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of STAT5A protein] |
CTD |
PMID:20523355 |
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NCBI chr10:86,285,859...86,310,187
Ensembl chr10:85,785,537...85,809,866
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G |
Stat6 |
signal transducer and activator of transcription 6 |
multiple interactions |
ISO |
[Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon co-treated with IL4 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL13 protein] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein co-treated with Nanotubes, Carbon] affects the phosphorylation of STAT6 protein; [Calcitriol co-treated with Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides co-treated with IL4 protein] affects the phosphorylation of STAT6 protein |
CTD |
PMID:26091108 |
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NCBI chr 7:65,365,505...65,382,825
Ensembl chr 7:63,479,642...63,498,495
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G |
Stk11 |
serine/threonine kinase 11 |
multiple interactions decreases phosphorylation |
ISO |
corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; maslinic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased phosphorylation of STK11 protein] |
CTD |
PMID:26513295 |
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NCBI chr 7:10,225,204...10,241,965
Ensembl chr 7:9,575,269...9,591,315
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G |
Stmn1 |
stathmin 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of STMN1 mRNA |
CTD |
PMID:19000923 |
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NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:146,681,436...146,687,154
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G |
Sts |
steroid sulfatase |
multiple interactions increases expression |
ISO |
prolinedithiocarbamate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; RELA protein affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of STS protein]; STS protein affects the reaction [Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]]; STS protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of Estradiol]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of STS protein Tetradecanoylphorbol Acetate results in increased expression of STS mRNA |
CTD |
PMID:26220752 PMID:31217279 |
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NCBI chr X:46,102,524...46,110,868
Ensembl chr X:42,225,372...42,233,402
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G |
Sumo2 |
small ubiquitin-like modifier 2 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SUMO2 mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:101,270,899...101,283,458
Ensembl chr10:100,686,797...100,784,513 Ensembl chr 5:100,686,797...100,784,513
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G |
Syn1 |
synapsin I |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SYN1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr X:3,725,745...3,780,940
Ensembl chr X:1,172,208...1,227,396
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G |
Syncrip |
synaptotagmin binding, cytoplasmic RNA interacting protein |
multiple interactions affects localization |
ISO |
Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate affects the localization of SYNCRIP protein] |
CTD |
PMID:19331829 |
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NCBI chr 8:98,282,358...98,315,412
Ensembl chr 8:89,402,866...89,435,515
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G |
Taf15 |
TATA-box binding protein associated factor 15 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TAF15 mRNA |
CTD |
PMID:16979875 |
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NCBI chr10:68,770,408...68,802,458
Ensembl chr10:68,272,969...68,304,949
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G |
Tagln |
transgelin |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TAGLN mRNA |
CTD |
PMID:15380616 |
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NCBI chr 8:55,121,647...55,127,121
Ensembl chr 8:46,222,472...46,230,668
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G |
Tasp1 |
taspase 1 |
multiple interactions increases methylation |
ISO |
corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of TASP1 gene] |
CTD |
PMID:32135139 |
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NCBI chr 3:147,630,092...147,861,710
Ensembl chr 3:127,176,692...127,399,600
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G |
Tat |
tyrosine aminotransferase |
multiple interactions |
EXP |
Sphingosine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [Dexamethasone results in increased activity of TAT protein]]; Tetradecanoylphorbol Acetate promotes the reaction [Dexamethasone results in increased activity of TAT protein] |
CTD |
PMID:9398635 |
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NCBI chr19:54,856,604...54,867,168
Ensembl chr19:37,947,112...37,958,031
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G |
Tbx21 |
T-box transcription factor 21 |
multiple interactions |
ISO |
[PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TBX21 mRNA] |
CTD |
PMID:22398747 |
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NCBI chr10:82,578,751...82,595,253
Ensembl chr10:82,082,322...82,098,831
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G |
Terf1 |
telomeric repeat binding factor 1 |
multiple interactions |
ISO |
[2,4,5,2',4',5'-hexachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TERF1 mRNA |
CTD |
PMID:26330309 |
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NCBI chr 5:8,226,345...8,255,614
Ensembl chr 5:3,443,106...3,472,340
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G |
Terf2 |
telomeric repeat binding factor 2 |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TERF2 mRNA 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TERF2 mRNA] |
CTD |
PMID:26330309 |
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NCBI chr19:51,887,221...51,915,756
Ensembl chr19:34,977,471...35,005,819
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G |
Tert |
telomerase reverse transcriptase |
decreases expression decreases activity multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TERT mRNA Tetradecanoylphorbol Acetate results in decreased activity of TERT protein 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [Tetradecanoylphorbol Acetate results in decreased activity of TERT protein] |
CTD |
PMID:26330309 |
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NCBI chr 1:31,465,766...31,488,650
Ensembl chr 1:29,637,506...29,659,561
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G |
Tfap2a |
transcription factor AP-2 alpha |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [gefitinib inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]] |
CTD |
PMID:21499124 PMID:21951556 |
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NCBI chr17:24,230,064...24,253,219
Ensembl chr17:24,024,432...24,047,507
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G |
Tff1 |
trefoil factor 1 |
multiple interactions increases expression |
ISO |
2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; 2-(1-(3-dimethylaminopropyl)-5-methoxyindol-3-yl)-3-(1H-indol-3-yl)maleimide inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein]]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein]]; Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]; Fulvestrant inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; Go 6976 inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]]; STS protein affects the reaction [Estrogens, Conjugated (USP) promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFF1 mRNA]]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [benz(a)anthracene results in increased expression of TFF1 protein] |
CTD |
PMID:22643241 PMID:31217279 |
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NCBI chr20:9,237,095...9,240,956
Ensembl chr20:9,235,736...9,239,597
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G |
Tfrc |
transferrin receptor |
multiple interactions decreases expression increases expression |
ISO EXP |
catechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein]; hydroquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TFRC protein] Tetradecanoylphorbol Acetate results in decreased expression of TFRC protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TFRC protein Tetradecanoylphorbol Acetate results in increased expression of TFRC mRNA |
CTD |
PMID:9766631 PMID:12749906 PMID:19000923 PMID:30218697 |
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NCBI chr11:81,668,478...81,690,318
Ensembl chr11:68,163,413...68,185,257
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions increases secretion |
ISO |
ADAM17 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein]; GW280264X inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TGFA protein]; Tetradecanoylphorbol Acetate results in increased cleavage of and results in increased secretion of TGFA protein |
CTD |
PMID:15066986 PMID:28703301 |
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NCBI chr 4:120,175,549...120,258,342
Ensembl chr 4:118,618,269...118,700,894
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases activity increases expression affects response to substance |
ISO |
[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 mRNA; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TGFB1 mRNA; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TGFB1 mRNA; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TGFB1 protein]; TGFB1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of HGF protein]; TGFB1 protein promotes the reaction [Tetradecanoylphorbol Acetate inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA; Tetradecanoylphorbol Acetate results in increased expression of TGFB1 protein TGFB1 affects the susceptibility to Tetradecanoylphorbol Acetate 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TGFB1 protein]; resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TGFB1 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and affects the localization of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased phosphorylation of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A8 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of S100A9 mRNA]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of SMAD2 protein]; TGFB1 affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of JUN protein]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate affects the localization of SMAD2 protein modified form]; TGFB1 promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of PRKCA protein] |
CTD |
PMID:8148055 PMID:10381133 PMID:11728381 PMID:15802798 PMID:16979875 PMID:18434080 PMID:20172950 PMID:20852150 PMID:25128825 PMID:27865421 PMID:30218697 More...
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NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TGFB2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405
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G |
Tgm1 |
transglutaminase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TGM1 mRNA |
CTD |
PMID:10866668 PMID:11485391 |
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NCBI chr15:33,160,985...33,175,632
Ensembl chr15:29,191,041...29,204,523
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G |
Tgm2 |
transglutaminase 2 |
multiple interactions decreases expression |
ISO |
Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA]; Phycocyanin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein] Tetradecanoylphorbol Acetate results in decreased expression of TGM2 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of TGM2 protein |
CTD |
PMID:22986104 |
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NCBI chr 3:167,192,612...167,221,845
Ensembl chr 3:146,772,687...146,801,981
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G |
Th |
tyrosine hydroxylase |
increases expression multiple interactions |
EXP ISO |
Tetradecanoylphorbol Acetate results in increased expression of TH mRNA [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TH protein |
CTD |
PMID:18992715 PMID:24101030 |
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NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767
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G |
Thbd |
thrombomodulin |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of THBD mRNA |
CTD |
PMID:31904401 |
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NCBI chr 3:156,316,526...156,320,178
Ensembl chr 3:135,862,835...135,867,193
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS1 mRNA |
CTD |
PMID:19840844 |
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NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440
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G |
Thbs2 |
thrombospondin 2 |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA; [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of THBS2 mRNA |
CTD |
PMID:19840844 PMID:23519560 |
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NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:55,670,394...55,699,789
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G |
Thpo |
thrombopoietin |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of THPO mRNA |
CTD |
PMID:16979875 |
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Ensembl chr11:80,182,820...80,188,167
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G |
Thy1 |
Thy-1 cell surface antigen |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of THY1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 8:53,286,396...53,291,541
Ensembl chr 8:44,389,513...44,394,659
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G |
Timm17a |
translocase of inner mitochondrial membrane 17A |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TIMM17A mRNA |
CTD |
PMID:16979875 |
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NCBI chr13:49,282,918...49,296,363
Ensembl chr13:46,730,660...46,742,655
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO |
Quercetin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA]; troglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TIMP1 mRNA] |
CTD |
PMID:11414687 PMID:18155510 PMID:20599481 |
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NCBI chr X:3,766,509...3,772,578
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
multiple interactions increases expression |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TIMP2 mRNA Tetradecanoylphorbol Acetate results in increased expression of TIMP2 protein |
CTD |
PMID:19840844 PMID:19969058 |
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NCBI chr10:104,041,604...104,089,214
Ensembl chr10:103,531,505...103,590,611
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G |
Tlr2 |
toll-like receptor 2 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TLR2 protein |
CTD |
PMID:28720485 |
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NCBI chr 2:171,499,189...171,504,831
Ensembl chr 2:169,197,419...169,206,630
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions increases expression |
ISO |
[epigallocatechin gallate co-treated with gallocatechol co-treated with epicatechin gallate co-treated with Catechin analog] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; gallocatechol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TLR4 protein]; TLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of CXCL8 mRNA]; TLR4 protein affects the reaction [[Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of CXCL8 protein] |
CTD |
PMID:23680697 PMID:26187476 PMID:28720485 |
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NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628
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G |
Tlr6 |
toll-like receptor 6 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TLR6 mRNA |
CTD |
PMID:16979875 |
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NCBI chr14:43,715,809...43,727,019
Ensembl chr14:43,362,164...43,375,685
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G |
Tnc |
tenascin C |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNC mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:77,375,851...77,460,624
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression increases secretion affects response to substance |
ISO EXP |
1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; 1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; 4'-hydroxydiclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of and results in increased secretion of TNF protein; [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Glucose co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNF mRNA; [Graphite analog co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] inhibits the reaction [semaglutide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of and results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Dinitrochlorobenzene] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with nickel sulfate] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Potassium Dichromate] results in increased expression of and results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Toluene 2,4-Diisocyanate] results in increased expression of and results in increased secretion of TNF protein; [Vitallium analog co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein; alpha-Tocopherol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Amiodarone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; butein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; CBR1 protein modified form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Ceftaroline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Tobacco Smoke Pollution] results in increased secretion of TNF protein]; chromic acid inhibits the reaction [[Glucose co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; chromic chloride inhibits the reaction [[Hydrogen Peroxide co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]; chrysin inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; cinnamaldehyde inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Cycloheximide inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; Diclofenac affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Doxycycline inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Eugenol inhibits the reaction [[Lipopolysaccharides co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; fisetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; fraxetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Fulvestrant inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; Fulvestrant inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]]; galangin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; geraniol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; hispidulin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Hydrocortisone affects the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; hydroquinone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Ionomycin inhibits the reaction [[N-(4-hydroxyphenyl)arachidonylamide co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; irosustat inhibits the reaction [Estrogens, Conjugated (USP) inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]]; isopraeroside IV inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; mancozeb inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Ozone promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Peptides inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of and results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; prolinedithiocarbamate inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; prolinedithiocarbamate inhibits the reaction [[Calcimycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Quercetin affects the reaction [beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of and results in increased secretion of TNF protein]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; Rutin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; SB 203580 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; SB 203580 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; sodium bichromate inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of TNF protein]; Spironolactone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Sulfasalazine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Tacrolimus inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF protein]; tetracycline CMT-3 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; tetracycline CMT-3 inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein; TNF affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]; Triclosan inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with TNF protein] results in increased expression of IL1B protein]; U 0126 inhibits the reaction [[bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein]; Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of TNF protein] Tetradecanoylphorbol Acetate results in increased expression of TNF; Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA; Tetradecanoylphorbol Acetate results in increased expression of TNF protein TNF protein affects the susceptibility to Tetradecanoylphorbol Acetate [Tetradecanoylphorbol Acetate results in increased expression of TNF] which results in increased expression of SOD2; Tetradecanoylphorbol Acetate results in increased expression of TNF; Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA; Tetradecanoylphorbol Acetate results in increased expression of TNF protein [Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; benzamide inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA]; phenanthridone inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF mRNA] 12-acetoxyhawtriwaic acid lactone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein; [Genistein co-treated with daidzein] inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; [IL17RA gene mutant form results in decreased susceptibility to Tetradecanoylphorbol Acetate] which results in decreased expression of TNF protein; [Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein; beta-elemene inhibits the reaction [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TNF protein]; bolinaquinone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Cannabidiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; centipedic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Clofibrate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; decursin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dexamethasone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; Eugenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with 9,10-Dimethyl-1,2-benzanthracene] results in increased secretion of TNF protein]; Famotidine inhibits the reaction [Dimaprit inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; FSCN1 mutant form affects the expression of [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; geraniol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; ginsenoside Re metabolite inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; ginsenoside Rh1 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]; HRH2 protein affects the reaction [Histamine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF protein]]; Indomethacin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; lactacystin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TNF mRNA]; SELENOS affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; Tetradecanoylphorbol Acetate inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [lipoteichoic acid results in increased expression of and results in increased secretion of TNF protein]]; Tetradecanoylphorbol Acetate promotes the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased abundance of Dinoprostone]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; yakuchinone B inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF mRNA]; yakuchinone-A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein] |
CTD |
PMID:1371491 PMID:9122163 PMID:9584910 PMID:9628260 PMID:10072544 PMID:10381133 PMID:10517978 PMID:10769695 PMID:10890505 PMID:11726202 PMID:11851881 PMID:12086399 PMID:12201673 PMID:12411406 PMID:12604694 PMID:12812920 PMID:14573775 PMID:14623498 PMID:15358692 PMID:16091123 PMID:16112155 PMID:16134060 PMID:16154495 PMID:16227999 PMID:16557482 PMID:17051331 PMID:17071120 PMID:17196940 PMID:17572062 PMID:17588137 PMID:17685462 PMID:18434080 PMID:18670081 PMID:18845389 PMID:18958421 PMID:19118619 PMID:19135038 PMID:19277450 PMID:19416633 PMID:19665545 PMID:20043298 PMID:20696233 PMID:20709134 PMID:21035309 PMID:21075198 PMID:21515303 PMID:21807015 PMID:22036979 PMID:22102721 PMID:22322153 PMID:22359662 PMID:22398747 PMID:22981962 PMID:23399806 PMID:23426871 PMID:23535185 PMID:23680697 PMID:24131540 PMID:24964617 PMID:25073960 PMID:25128825 PMID:25446327 PMID:25818598 PMID:27325435 PMID:28087840 PMID:28720485 PMID:29458014 PMID:29777833 PMID:30254419 PMID:30496664 PMID:30796934 PMID:31068361 PMID:31195760 PMID:31217279 PMID:31351099 PMID:32662567 PMID:33268675 PMID:34051231 PMID:34506768 PMID:36075570 PMID:36416909 More...
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NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629
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Tnfaip3 |
TNF alpha induced protein 3 |
decreases expression multiple interactions increases expression increases activity |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TNFAIP3 mRNA 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TNFAIP3 protein]; Zinc deficiency inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFAIP3 mRNA]; Zinc promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]] |
CTD |
PMID:15451058 PMID:20438634 PMID:21035309 PMID:21873647 PMID:31068361 |
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NCBI chr 1:15,528,921...15,543,993
Ensembl chr 1:13,709,206...13,725,282
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Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions increases expression decreases expression |
ISO |
1,3-dimethylthiourea inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; calphostin C inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; Dimethyl Sulfoxide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein]; KB R8301 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1A protein] Tetradecanoylphorbol Acetate results in decreased expression of TNFRSF1A protein |
CTD |
PMID:9870925 PMID:11882518 |
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NCBI chr 4:159,837,119...159,849,817
Ensembl chr 4:158,150,820...158,163,591
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions increases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA; NFKBIA protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF1B protein] |
CTD |
PMID:10072544 PMID:15477007 |
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NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206
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Tnfrsf21 |
TNF receptor superfamily member 21 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Benzo(a)pyrene co-treated with Particulate Matter] results in increased expression of TNFRSF21 mRNA |
CTD |
PMID:18353537 |
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NCBI chr 9:25,376,400...25,451,323
Ensembl chr 9:17,879,156...17,954,085
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Tnfrsf4 |
TNF receptor superfamily member 4 |
multiple interactions increases expression |
EXP |
Cyclosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]]; Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Mercuric Chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Staurosporine inhibits the reaction [Ionomycin promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein]]; Staurosporine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNFRSF4 protein]; Tetradecanoylphorbol Acetate promotes the reaction [IL4 protein results in increased expression of TNFRSF4 protein] |
CTD |
PMID:9766631 |
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NCBI chr 5:171,889,134...171,891,824
Ensembl chr 5:166,606,909...166,609,599
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Tnfrsf8 |
TNF receptor superfamily member 8 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TNFRSF8 mRNA |
CTD |
PMID:9933429 |
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NCBI chr 5:162,406,387...162,451,620
Ensembl chr 5:157,123,185...157,168,421
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Tnfrsf9 |
TNF receptor superfamily member 9 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TNFRSF9 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 5:166,664,494...166,690,834
Ensembl chr 5:161,381,662...161,408,000
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Tnfsf10 |
TNF superfamily member 10 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein; Cyclosporine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC1 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC2 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC3 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein]; NFATC4 protein promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNFSF10 protein] |
CTD |
PMID:21603612 |
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NCBI chr 2:112,136,550...112,155,903
Ensembl chr 2:110,207,916...110,225,135
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Tnfsf11 |
TNF superfamily member 11 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TNFSF11 mRNA |
CTD |
PMID:17306214 |
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NCBI chr15:60,083,008...60,114,479
Ensembl chr15:53,673,877...53,705,445
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G |
Tnfsf8 |
TNF superfamily member 8 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TNFSF8 mRNA |
CTD |
PMID:9933429 |
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NCBI chr 5:82,266,436...82,292,858
Ensembl chr 5:77,251,373...77,277,421
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Tnni3 |
troponin I3, cardiac type |
multiple interactions |
ISO |
chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNI3 protein] |
CTD |
PMID:12003851 |
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NCBI chr 1:78,342,571...78,346,255
Ensembl chr 1:69,299,900...69,303,580
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Tnnt2 |
troponin T2, cardiac type |
multiple interactions |
ISO |
chelerythrine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TNNT2 protein] |
CTD |
PMID:12003851 |
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NCBI chr13:49,819,123...49,837,125
Ensembl chr13:47,267,204...47,285,388
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G |
Top2a |
DNA topoisomerase II alpha |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TOP2A mRNA |
CTD |
PMID:19840844 |
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NCBI chr10:84,441,954...84,473,093
Ensembl chr10:83,945,735...83,976,874
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Tp53 |
tumor protein p53 |
decreases expression increases phosphorylation multiple interactions |
ISO EXP |
Tetradecanoylphorbol Acetate results in decreased expression of TP53 protein Tetradecanoylphorbol Acetate results in increased phosphorylation of TP53 protein Tetradecanoylphorbol Acetate inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of and affects the localization of TP53 protein] |
CTD |
PMID:8076368 PMID:8927716 PMID:10910098 PMID:15542774 |
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NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524
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Tpd52 |
tumor protein D52 |
decreases expression increases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TPD52 mRNA Tetradecanoylphorbol Acetate results in increased expression of TPD52 mRNA |
CTD |
PMID:21873647 |
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NCBI chr 2:94,642,514...94,723,442
Ensembl chr 2:92,735,620...92,816,622
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Tpx2 |
TPX2, microtubule nucleation factor |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TPX2 mRNA |
CTD |
PMID:19031421 |
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NCBI chr 3:161,778,709...161,820,941
Ensembl chr 3:141,318,455...141,360,468
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Traf1 |
TNF receptor-associated factor 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]; Zinc promotes the reaction [Tetradecanoylphorbol Acetate promotes the reaction [TRAF1 protein binds to TNFAIP3 protein]] |
CTD |
PMID:15477007 PMID:21035309 |
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NCBI chr 3:38,607,707...38,639,641
Ensembl chr 3:18,222,054...18,241,807
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Traf6 |
TNF receptor associated factor 6 |
multiple interactions decreases expression |
ISO |
hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 mRNA]; hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]; MIR146A mRNA affects the reaction [hydroquinone promotes the reaction [Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein]] Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of TRAF6 protein |
CTD |
PMID:30090394 |
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NCBI chr 3:108,418,537...108,443,330
Ensembl chr 3:87,963,514...87,983,507
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Trh |
thyrotropin releasing hormone |
multiple interactions |
EXP ISO |
TRH protein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of IREB2 protein] Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of ACO1 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [TRH protein results in increased activity of IREB2 protein] |
CTD |
PMID:10889193 |
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NCBI chr 4:126,299,236...126,301,762
Ensembl chr 4:124,742,111...124,744,637
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Trhde |
thyrotropin-releasing hormone degrading enzyme |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of TRHDE mRNA |
CTD |
PMID:16979875 |
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NCBI chr 7:51,829,473...52,236,843
Ensembl chr 7:49,945,766...50,367,371
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Trib2 |
tribbles pseudokinase 2 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 6:44,274,762...44,299,139
Ensembl chr 6:38,545,975...38,569,370
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Trim7 |
tripartite motif-containing 7 |
multiple interactions |
ISO |
TRIM7 mutant form inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RNF187 protein] |
CTD |
PMID:25851810 |
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NCBI chr10:33,706,614...33,722,609
Ensembl chr10:33,205,491...33,221,468
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G |
Trnp1 |
TMF1-regulated nuclear protein 1 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of TRNP1 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 5:145,706,427...145,713,279
Ensembl chr 5:145,706,094...145,713,272
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G |
Trpa1 |
transient receptor potential cation channel, subfamily A, member 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of TRPA1 mRNA |
CTD |
PMID:36847817 |
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NCBI chr 5:9,163,060...9,217,325
Ensembl chr 5:4,379,999...4,433,570
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G |
Trpc3 |
transient receptor potential cation channel, subfamily C, member 3 |
increases expression |
EXP |
Tetradecanoylphorbol Acetate results in increased expression of TRPC3 mRNA |
CTD |
PMID:19244478 |
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NCBI chr 2:121,409,436...121,487,095
Ensembl chr 2:119,481,400...119,558,855
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases expression increases activity increases localization |
ISO EXP |
Tetradecanoylphorbol Acetate inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] Tetradecanoylphorbol Acetate results in increased expression of TRPV1 mRNA Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein Tetradecanoylphorbol Acetate results in increased localization of TRPV1 protein bisindolylmaleimide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Capsaicin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; capsazepine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Ruthenium Red inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate affects the reaction [resiniferatoxin affects the reaction [[Sodium Chloride co-treated with benzamil] results in increased activity of TRPV1 protein]]; Tetradecanoylphorbol Acetate inhibits the reaction [resiniferatoxin binds to TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Capsaicin results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [Lidocaine results in increased activity of TRPV1 protein] RTKI cpd inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]]; Tetradecanoylphorbol Acetate results in increased phosphorylation of and affects the activity of TRPV1 protein; TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]; TRPV1 results in decreased susceptibility to [Capsaicin co-treated with Tetradecanoylphorbol Acetate]; U 0126 inhibits the reaction [TRPV1 gene mutant form promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased expression of PTGS2 protein]] |
CTD |
PMID:11140687 PMID:15363968 PMID:16319926 PMID:17913835 PMID:18172555 PMID:19553475 PMID:20660715 PMID:36847817 More...
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NCBI chr10:58,349,936...58,375,021
Ensembl chr10:57,851,428...57,876,513
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G |
Tsc2 |
TSC complex subunit 2 |
increases phosphorylation multiple interactions |
EXP |
Tetradecanoylphorbol Acetate results in increased phosphorylation of TSC2 protein U 0126 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of TSC2 protein] |
CTD |
PMID:15757502 |
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NCBI chr10:14,125,679...14,160,317
Ensembl chr10:13,621,136...13,655,951
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G |
Tslp |
thymic stromal lymphopoietin |
increases expression multiple interactions increases secretion |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA phorbol 12-myristate 13-acetate increases expression of Tslp protein in keratinocytes Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA; Tetradecanoylphorbol Acetate results in increased expression of TSLP protein FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP protein]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; lithol rubine BCA analog promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; lithol rubine BCA promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TSLP protein] [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA; [Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein; Dexamethasone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein]; FK3453 inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TSLP mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA]; naringin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP mRNA]; Plant Preparations inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TSLP protein] |
CTD RGD |
PMID:18049884 PMID:24131540 PMID:29462589 PMID:35717073 PMID:29310423 |
RGD:38549374 |
NCBI chr18:24,723,990...24,728,419
Ensembl chr18:24,449,844...24,453,548
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G |
Ttc3 |
tetratricopeptide repeat domain 3 |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TTC3 mRNA |
CTD |
PMID:19840844 |
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NCBI chr11:47,158,766...47,258,612
Ensembl chr11:33,688,952...33,788,975
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G |
Twf2 |
twinfilin actin-binding protein 2 |
multiple interactions |
ISO |
[Dibutyl Phthalate co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of TWF2 protein |
CTD |
PMID:30218697 |
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NCBI chr 8:115,723,980...115,737,025
Ensembl chr 8:106,845,253...106,858,298
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G |
Txn1 |
thioredoxin 1 |
multiple interactions increases expression |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of TXN1 mRNA Tetradecanoylphorbol Acetate results in increased expression of TXN mRNA |
CTD |
PMID:19840844 PMID:24632381 |
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NCBI chr 5:77,507,455...77,519,685
Ensembl chr 5:72,711,933...72,724,629
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TXNRD1 mRNA |
CTD |
PMID:12949356 |
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NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:20,830,045...20,907,863
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G |
Tymp |
thymidine phosphorylase |
multiple interactions increases expression increases activity |
ISO |
Aspirin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]; TNF affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA] Tetradecanoylphorbol Acetate results in increased activity of TYMP protein |
CTD |
PMID:14573775 |
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NCBI chr 7:122,318,396...122,323,716
Ensembl chr 7:120,438,770...120,443,874 Ensembl chr 7:120,438,770...120,443,874
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G |
Tyms |
thymidylate synthetase |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of TYMS mRNA |
CTD |
PMID:19031421 |
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NCBI chr 9:120,760,057...120,776,149
Ensembl chr 9:113,313,452...113,329,536
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G |
Tyr |
tyrosinase |
multiple interactions |
ISO |
[9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with argemone oil]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with [Tetradecanoylphorbol Acetate co-treated with sanguinarine]] results in decreased activity of TYR protein; [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with argemone oil] results in decreased activity of TYR protein; [[9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] co-treated with sanguinarine] results in decreased activity of TYR protein |
CTD |
PMID:20691676 |
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NCBI chr 1:150,527,687...150,622,857
Ensembl chr 1:141,115,036...141,210,207
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G |
Tyrobp |
transmembrane immune signaling adaptor Tyrobp |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:94,800,372...94,804,307
Ensembl chr 1:85,672,994...85,676,848
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G |
Ubc |
ubiquitin C |
multiple interactions |
ISO |
[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA |
CTD |
PMID:19840844 |
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NCBI chr12:36,899,673...36,905,275
Ensembl chr12:31,239,152...31,243,925
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G |
Uhrf1 |
ubiquitin-like with PHD and ring finger domains 1 |
decreases expression |
ISO |
Tetradecanoylphorbol Acetate results in decreased expression of UHRF1 mRNA; Tetradecanoylphorbol Acetate results in decreased expression of UHRF1 protein |
CTD |
PMID:15964557 |
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NCBI chr 9:1,220,162...1,241,792
Ensembl chr 9:1,134,909...1,154,631
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G |
Ulbp1 |
UL16 binding protein 1 |
multiple interactions |
ISO |
Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [Erlotinib Hydrochloride results in increased expression of ULBP1 mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [Gefitinib inhibits the reaction [TFAP2A protein binds to ULBP1 promoter]]; Tetradecanoylphorbol Acetate inhibits the reaction [Gefitinib results in increased expression of ULBP1 mRNA] |
CTD |
PMID:21499124 PMID:21951556 |
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NCBI chr 1:3,506,106...3,527,982
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G |
Ulk1 |
unc-51 like autophagy activating kinase 1 |
multiple interactions |
ISO |
[maslinic acid analog co-treated with Tetradecanoylphorbol Acetate] results in increased phosphorylation of ULK1 protein |
CTD |
PMID:26513295 |
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NCBI chr12:51,511,492...51,537,746
Ensembl chr12:45,851,710...45,877,966
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G |
Uri1 |
URI1, prefoldin-like chaperone |
increases methylation multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene] |
CTD |
PMID:32135139 |
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NCBI chr 1:99,783,157...99,845,787
Ensembl chr 1:90,646,393...90,709,026
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G |
Usp18 |
ubiquitin specific peptidase 18 |
multiple interactions |
ISO |
[Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of USP18 mRNA |
CTD |
PMID:31904401 |
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NCBI chr 4:156,143,770...156,171,292
Ensembl chr 4:154,471,592...154,499,144
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
3,4-dihydroxyphenylethanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; oleuropein inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of VCAM1 protein; Zinc inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased secretion of VCAM1 protein] |
CTD |
PMID:12615669 PMID:21035309 |
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NCBI chr 2:206,723,050...206,742,783
Ensembl chr 2:204,038,114...204,057,958
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G |
Vdr |
vitamin D receptor |
multiple interactions increases expression |
ISO EXP |
Tetradecanoylphorbol Acetate promotes the reaction [salvin results in increased expression of VDR protein] Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA] Tetradecanoylphorbol Acetate results in increased expression of VDR mRNA; Tetradecanoylphorbol Acetate results in increased expression of VDR protein |
CTD |
PMID:9348195 PMID:11504768 PMID:20006981 |
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NCBI chr 7:130,864,764...130,916,757
Ensembl chr 7:128,987,981...129,037,677
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases secretion increases expression decreases expression |
ISO EXP |
5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [ABCB1 protein results in decreased susceptibility to Doxorubicin] affects the reaction [eriodictyol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]]; [Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA mRNA; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA protein; [Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein modified form; [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of VEGFA mRNA; Acetylcysteine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of VEGFA protein]; eriodictyol affects the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; kaempferol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Quercetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate inhibits the reaction [VEGFA protein results in increased expression of ACE protein]; withaferin A inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA] [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] which results in decreased expression of PRKCE protein; Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA]; PRKCE protein affects the reaction [Tetradecanoylphorbol Acetate results in decreased expression of VEGFA mRNA] [Norepinephrine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of VEGFA mRNA; augustic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; corosolic acid analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; maslinic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VEGFA mRNA]; Tetradecanoylphorbol Acetate promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA] |
CTD |
PMID:8537383 PMID:9743532 PMID:10788502 PMID:11158990 PMID:11214823 PMID:12590138 PMID:16979875 PMID:19000923 PMID:19063610 PMID:19910455 PMID:20438634 PMID:26513295 More...
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NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein]; [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA]; [Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA; Curcumin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein] [sodium arsenite results in increased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate]] which results in increased expression of VIM protein; morusin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VIM protein] |
CTD |
PMID:15477007 PMID:25656647 PMID:28108223 PMID:35364107 |
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NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187
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G |
Vipr2 |
vasoactive intestinal peptide receptor 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of VIPR2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 6:143,139,672...143,213,609
Ensembl chr 6:137,001,511...137,070,597
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G |
Vit |
vitrin |
multiple interactions |
ISO |
[Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of VIT mRNA |
CTD |
PMID:23519560 |
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NCBI chr 6:16,445,966...16,565,644
Ensembl chr 6:16,445,955...16,565,665
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G |
Vsnl1 |
visinin-like 1 |
multiple interactions decreases response to substance |
ISO |
VSNL1 protein results in decreased susceptibility to [9,10-Dimethyl-1,2-benzanthracene co-treated with Tetradecanoylphorbol Acetate] VSNL1 protein results in decreased susceptibility to Tetradecanoylphorbol Acetate |
CTD |
PMID:20419170 |
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NCBI chr 6:39,757,721...39,878,556
Ensembl chr 6:34,038,642...34,159,479
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions increases activity |
ISO |
Allopurinol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]]; caffeic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; Fluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]; Tetradecanoylphorbol Acetate promotes the reaction [XDH protein results in increased chemical synthesis of Uric Acid]; Tretinoin promotes the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein] |
CTD |
PMID:3677084 PMID:22036979 |
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NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:21,530,113...21,592,268
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G |
Yy1 |
YY1 transcription factor |
increases expression multiple interactions |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of YY1 protein [bisphenol A co-treated with Tetradecanoylphorbol Acetate] results in increased expression of YY1 protein |
CTD |
PMID:32363662 |
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NCBI chr 6:133,471,615...133,500,875
Ensembl chr 6:127,707,596...127,732,747
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G |
Zc3h12a |
zinc finger CCCH type containing 12A |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ZC3H12A mRNA |
CTD |
PMID:31068361 |
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NCBI chr 5:142,661,193...142,670,051
Ensembl chr 5:137,376,564...137,385,351
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G |
Zeb1 |
zinc finger E-box binding homeobox 1 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZEB1 mRNA [Tetradecanoylphorbol Acetate co-treated with Ionomycin] promotes the reaction [deoxynivalenol results in decreased expression of ZEB1 protein] |
CTD |
PMID:11893416 PMID:16979875 |
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NCBI chr17:56,644,397...56,811,155
Ensembl chr17:51,948,948...52,115,214
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G |
Zeb2 |
zinc finger E-box binding homeobox 2 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZEB2 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157
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G |
Zfp36 |
zinc finger protein 36 |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ZFP36 mRNA |
CTD |
PMID:19945525 PMID:31068361 |
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NCBI chr 1:92,796,628...92,799,108
Ensembl chr 1:83,669,084...83,671,564
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G |
Znf235 |
zinc finger protein 235 |
multiple interactions |
ISO |
[Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of ZNF235 mRNA |
CTD |
PMID:16979875 |
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NCBI chr 1:88,826,910...88,836,360
Ensembl chr 1:79,698,911...79,708,501
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G |
Zwint |
ZW10 interacting kinetochore protein |
increases expression |
ISO |
Tetradecanoylphorbol Acetate results in increased expression of ZWINT mRNA |
CTD |
PMID:19031421 |
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NCBI chr20:15,502,559...15,953,701
Ensembl chr20:15,938,157...15,953,957
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