Vipr2 (vasoactive intestinal peptide receptor 2) - Rat Genome Database

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Gene: Vipr2 (vasoactive intestinal peptide receptor 2) Rattus norvegicus
Analyze
Symbol: Vipr2
Name: vasoactive intestinal peptide receptor 2
RGD ID: 3962
Description: Enables vasoactive intestinal polypeptide receptor activity. Involved in activation of adenylate cyclase activity and negative regulation of smooth muscle cell proliferation. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in schizophrenia 16. Orthologous to human VIPR2 (vasoactive intestinal peptide receptor 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: PACAP type III receptor; PACAP-R-3; PACAP-R3; pituitary adenylate cyclase-activating polypeptide type III receptor; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP-R-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26136,996,664 - 137,070,599 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl6143,938,040 - 144,008,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06143,932,960 - 144,009,476 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06152,871,204 - 152,945,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,347,748 - 143,416,680 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16143,353,934 - 143,422,867 (+)NCBI
Celera6134,667,982 - 134,736,986 (+)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:15176082   PMID:15344914   PMID:15514088   PMID:15670850   PMID:16202621   PMID:16888168   PMID:16888209   PMID:18665096   PMID:20599818   PMID:22766684   PMID:23099490   PMID:23518767  
PMID:28776455  


Genomics

Comparative Map Data
Vipr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26136,996,664 - 137,070,599 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl6143,938,040 - 144,008,072 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06143,932,960 - 144,009,476 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06152,871,204 - 152,945,276 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,347,748 - 143,416,680 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16143,353,934 - 143,422,867 (+)NCBI
Celera6134,667,982 - 134,736,986 (+)NCBICelera
Cytogenetic Map6q33NCBI
VIPR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7159,028,175 - 159,144,867 (-)EnsemblGRCh38hg38GRCh38
GRCh387159,028,175 - 159,144,957 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377158,820,866 - 158,937,559 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367158,513,627 - 158,630,410 (-)NCBINCBI36hg18NCBI36
Build 347158,320,342 - 158,437,125NCBI
Celera7153,254,268 - 153,370,389 (-)NCBI
Cytogenetic Map7q36.3NCBI
HuRef7152,560,564 - 152,677,411 (-)NCBIHuRef
CHM1_17158,828,828 - 158,945,965 (-)NCBICHM1_1
CRA_TCAGchr7v27158,024,240 - 158,139,944 (-)NCBI
Vipr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912116,041,040 - 116,117,842 (+)NCBIGRCm39mm39
GRCm39 Ensembl12116,041,346 - 116,109,881 (+)Ensembl
GRCm3812116,077,420 - 116,148,637 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12116,077,726 - 116,146,261 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712117,316,196 - 117,384,734 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612116,519,807 - 116,587,384 (+)NCBImm8
MGSCv3612110,280,083 - 110,347,578 (+)NCBImm8
Cytogenetic Map12F2NCBI
cM Map1262.59NCBI
Vipr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555791,160,620 - 1,209,848 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555791,160,620 - 1,212,711 (-)NCBIChiLan1.0ChiLan1.0
VIPR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17162,306,477 - 162,425,860 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7162,306,477 - 162,422,788 (-)Ensemblpanpan1.1panPan2
VIPR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11620,925,032 - 20,987,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1620,927,991 - 20,987,785 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1621,432,331 - 21,491,528 (-)NCBI
ROS_Cfam_1.01622,660,335 - 22,719,946 (-)NCBI
UMICH_Zoey_3.11621,028,013 - 21,087,077 (-)NCBI
UNSW_CanFamBas_1.01621,611,058 - 21,670,421 (-)NCBI
UU_Cfam_GSD_1.01621,665,914 - 21,725,151 (-)NCBI
Vipr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118328,956 - 410,359 (+)NCBI
SpeTri2.0NW_004936856859,009 - 866,239 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VIPR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18396,263 - 518,102 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118396,379 - 466,408 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218663,352 - 732,192 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VIPR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121126,917,862 - 127,022,834 (-)NCBI
ChlSab1.1 Ensembl21126,917,880 - 127,022,758 (-)Ensembl
Vero_WHO_p1.0NW_02366607223,466,663 - 23,573,079 (-)NCBI
Vipr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624800125,732 - 188,200 (+)NCBI

Position Markers
AA818985  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,026,116 - 137,026,330 (+)MAPPERmRatBN7.2
Rnor_6.06143,962,568 - 143,962,781NCBIRnor6.0
Rnor_5.06152,900,814 - 152,901,027UniSTSRnor5.0
RGSC_v3.46143,372,355 - 143,372,568UniSTSRGSC3.4
Celera6134,692,589 - 134,692,802UniSTS
RH 3.4 Map6916.0UniSTS
Cytogenetic Map6q33UniSTS
RH132714  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,070,351 - 137,070,551 (+)MAPPERmRatBN7.2
Rnor_6.06144,006,783 - 144,006,982NCBIRnor6.0
Rnor_5.06152,945,029 - 152,945,228UniSTSRnor5.0
RGSC_v3.46143,416,435 - 143,416,634UniSTSRGSC3.4
Celera6134,736,741 - 134,736,940UniSTS
RH 3.4 Map6914.1UniSTS
Cytogenetic Map6q33UniSTS
RH139640  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,007,693 - 137,007,898 (+)MAPPERmRatBN7.2
Rnor_6.06143,944,144 - 143,944,348NCBIRnor6.0
Rnor_5.06152,882,390 - 152,882,594UniSTSRnor5.0
RGSC_v3.46143,353,931 - 143,354,135UniSTSRGSC3.4
Celera6134,674,165 - 134,674,369UniSTS
RH 3.4 Map6916.3UniSTS
Cytogenetic Map6q33UniSTS
UniSTS:224723  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.26137,068,736 - 137,068,891 (+)MAPPERmRatBN7.2
Rnor_6.06144,005,168 - 144,005,322NCBIRnor6.0
Rnor_5.06152,943,414 - 152,943,568UniSTSRnor5.0
RGSC_v3.46143,414,820 - 143,414,974UniSTSRGSC3.4
Celera6134,735,126 - 134,735,280UniSTS
Cytogenetic Map6q33UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)668781170147991367Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)699273921144273921Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)699273921144792678Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)6101207574147991367Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6104363890147991367Rat
737976Pia24Pristane induced arthritis QTL 24joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)6117355600147991367Rat
1641917Colcr5Colorectal carcinoma resistance QTL 53.180.0009intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)6127286494144745573Rat
2293085Iddm29Insulin dependent diabetes mellitus QTL 297.66blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)6127286494147249902Rat
61329Eae9Experimental allergic encephalomyelitis QTL 93.7body mass (VT:0001259)change in body weight (CMO:0002045)6127286494147991367Rat
2312560Pur20Proteinuria QTL 202.10.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)6130561943144745573Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:240
Count of miRNA genes:166
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000005876
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4
Low 3 37 34 18 19 18 5 6 74 34 35 11 5
Below cutoff 6 23 23 23 3 5 1 2 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000005876   ⟹   ENSRNOP00000005876
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl6143,938,040 - 144,008,072 (+)Ensembl
RefSeq Acc Id: NM_017238   ⟹   NP_058934
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,001,511 - 137,070,597 (+)NCBI
Rnor_6.06143,937,961 - 144,007,028 (+)NCBI
Rnor_5.06152,871,204 - 152,945,276 (+)NCBI
RGSC_v3.46143,347,748 - 143,416,680 (+)RGD
Celera6134,667,982 - 134,736,986 (+)RGD
Sequence:
RefSeq Acc Id: XM_017594055   ⟹   XP_017449544
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26136,996,664 - 137,070,599 (+)NCBI
Rnor_6.06143,932,960 - 144,007,028 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039111850   ⟹   XP_038967778
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,001,486 - 137,070,599 (+)NCBI
RefSeq Acc Id: XM_039111851   ⟹   XP_038967779
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,017,480 - 137,070,599 (+)NCBI
RefSeq Acc Id: XM_039111852   ⟹   XP_038967780
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,001,487 - 137,067,252 (+)NCBI
RefSeq Acc Id: XM_039111853   ⟹   XP_038967781
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,001,275 - 137,020,533 (+)NCBI
RefSeq Acc Id: XR_005505447
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.26137,001,488 - 137,067,252 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_058934   ⟸   NM_017238
- Peptide Label: precursor
- Sequence:
RefSeq Acc Id: XP_017449544   ⟸   XM_017594055
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000005876   ⟸   ENSRNOT00000005876
RefSeq Acc Id: XP_038967781   ⟸   XM_039111853
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038967778   ⟸   XM_039111850
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038967780   ⟸   XM_039111852
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038967779   ⟸   XM_039111851
- Peptide Label: isoform X3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694906
Promoter ID:EPDNEW_R5430
Type:single initiation site
Name:Vipr2_1
Description:vasoactive intestinal peptide receptor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.06143,938,031 - 143,938,091EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3962 AgrOrtholog
Ensembl Genes ENSRNOG00000004317 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSRNOP00000005876 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000005876 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.1240.10 UniProtKB/Swiss-Prot
InterPro GPCR_2-like UniProtKB/Swiss-Prot
  GPCR_2_extracell_dom_sf UniProtKB/Swiss-Prot
  GPCR_2_extracellular_dom UniProtKB/Swiss-Prot
  GPCR_2_secretin-like UniProtKB/Swiss-Prot
  GPCR_2_secretin-like_CS UniProtKB/Swiss-Prot
  GPCR_2_VIP_rcpt UniProtKB/Swiss-Prot
  GPCR_2_VIP_rcpt_2 UniProtKB/Swiss-Prot
KEGG Report rno:29555 UniProtKB/Swiss-Prot
NCBI Gene 29555 ENTREZGENE
PANTHER PTHR45620:SF22 UniProtKB/Swiss-Prot
Pfam 7tm_2 UniProtKB/Swiss-Prot
  HRM UniProtKB/Swiss-Prot
PhenoGen Vipr2 PhenoGen
PRINTS GPCRSECRETIN UniProtKB/Swiss-Prot
  VASOACTVEIPR UniProtKB/Swiss-Prot
  VIP2RECEPTOR UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F2_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_2 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_3 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F2_4 UniProtKB/Swiss-Prot
SMART HormR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF111418 UniProtKB/Swiss-Prot
TIGR TC232082
UniProt P35000 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Vipr2  vasoactive intestinal peptide receptor 2    vasopressive intestinal peptide receptor 2  Name updated 1299863 APPROVED
2002-06-10 Vipr2  vasopressive intestinal peptide receptor 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expressed in areas associated with neuroendocrine function, including hypothalamic nuclei, pituitary and pancreatic islets 70053
gene_physical_interaction may also bind growth hormone releasing hormone and peptide histidine isoleucine 70054
gene_process stimulates cAMP production in response to VIP binding 70053
gene_product member of the secretin/calcitonin/parathyroid hormone receptor family 70054