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Gene: Crtam (cytotoxic and regulatory T cell molecule) Rattus norvegicus
Symbol: Crtam
Name: cytotoxic and regulatory T cell molecule
Description: Predicted to have identical protein binding activity and signaling receptor binding activity. Predicted to be involved in several processes, including detection of tumor cell; positive regulation of cytokine secretion; and positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target. Predicted to localize to the plasma membrane. Orthologous to human CRTAM (cytotoxic and regulatory T cell molecule); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; 17beta-estradiol (ortholog).
Type: protein-coding
Also known as: cytotoxic and regulatory T-cell molecule; LOC300649
Homo sapiens (human) : CRTAM (cytotoxic and regulatory T cell molecule)  HGNC  Alliance
Mus musculus (house mouse) : Crtam (cytotoxic and regulatory T cell molecule)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crtam (cytotoxic and regulatory T cell molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CRTAM (cytotoxic and regulatory T cell molecule)
Canis lupus familiaris (dog) : CRTAM (cytotoxic and regulatory T cell molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crtam (cytotoxic and regulatory T cell molecule)
Sus scrofa (pig) : CRTAM (cytotoxic and regulatory T cell molecule)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0845,152,584 - 45,216,082 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0843,634,852 - 43,653,181 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0843,681,605 - 43,694,465 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4843,943,971 - 43,981,609 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1843,953,456 - 43,984,145 (-)NCBI
Celera840,939,600 - 40,975,292 (-)NCBICelera
Cytogenetic Map8q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Crtam
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1304602
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.