CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 6-formylpterin
Accession: CHEBI:70981
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Definition: Pterin carrying a formyl group at position 6.
Synonyms: exact_synonym: 2-amino-4-oxo-3,4-dihydropteridine-6-carbaldehyde
related_synonym: 2-amino-1,4-dihydro-4-oxo-6-pteridinecarboxaldehyde; 2-amino-3,4-dihydro-4-oxo-6-pteridinecarboxaldehyde; 2-amino-4-hydroxy-6-formylpteridine; 2-amino-4-hydroxy-6-pteridinecarboxaldehyde; 2-amino-4-hydroxy-6-pteridylcarboxaldehyde; 2-amino-4-hydroxypteridine-6-carboxaldehyde; 2-amino-6-formylpteridin-4-one; Formula=C7H5N5O2; InChI=1S/C7H5N5O2/c8-7-11-5-4(6(14)12-7)10-3(2-13)1-9-5/h1-2H,(H3,8,9,11,12,14); InChIKey=LLJAQDVNMGLRBD-UHFFFAOYSA-N; Pterin-6-aldehyde; SMILES=[H]C(=O)c1cnc2nc(N)[nH]c(=O)c2n1
xref: CAS:712-30-1
xref_mesh: MESH:C005926
xref: PMID:10699495; PMID:11165871; PMID:11708781; PMID:12713224; PMID:12856711; PMID:14570282; PMID:15006553; PMID:15190933; PMID:15964307; PMID:15964552; PMID:16019850; PMID:17978497; PMID:19165694; PMID:3753555; PMID:9144555; PMID:9507930; Reaxys:192176
G
Bid
BH3 interacting domain death agonist
decreases expression
ISO
2-amino-4-hydroxy-6-formylpteridine results in decreased expression of BID protein
CTD
PMID:16019850
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
G
Casp3
caspase 3
increases activity
ISO
2-amino-4-hydroxy-6-formylpteridine results in increased activity of CASP3 protein
CTD
PMID:16019850
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
G
Casp8
caspase 8
increases activity
ISO
2-amino-4-hydroxy-6-formylpteridine results in increased activity of CASP8 protein
CTD
PMID:16019850
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
G
Cycs
cytochrome c, somatic
affects localization
ISO
2-amino-4-hydroxy-6-formylpteridine affects the localization of CYCS protein
CTD
PMID:16019850
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
G
Prkcd
protein kinase C, delta
affects localization
ISO
2-amino-4-hydroxy-6-formylpteridine affects the localization of PRKCD protein
CTD
PMID:16019850
NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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