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Gene: Prkci (protein kinase C, iota) Rattus norvegicus
Symbol: Prkci
Name: protein kinase C, iota
RGD ID: 620961
Description: Predicted to have phospholipid binding activity and protein kinase C activity. Involved in several processes, including Golgi vesicle budding; cellular response to insulin stimulus; and response to interleukin-1. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; cell leading edge; and glutamatergic synapse. Colocalizes with bicellular tight junction. Orthologous to human PRKCI (protein kinase C iota); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin signaling pathway; interleukin-1 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aPKC-lambda/iota; atypical protein kinase C-lambda/iota; nPKC-iota; Pkcl; protein kinase C iota type; protein kinase C, lambda
Homo sapiens (human) : PRKCI (protein kinase C iota)  HGNC  Alliance
Mus musculus (house mouse) : Prkci (protein kinase C, iota)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkci (protein kinase C iota)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCI (protein kinase C iota)
Canis lupus familiaris (dog) : PRKCI (protein kinase C iota)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkci (protein kinase C iota)
Sus scrofa (pig) : PRKCI (protein kinase C iota)
Chlorocebus sabaeus (African green monkey) : PRKCI (protein kinase C iota)
Heterocephalus glaber (naked mole-rat) : Prkci (protein kinase C iota)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02115,941,998 - 116,002,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2115,941,993 - 116,002,561 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02135,636,956 - 135,697,732 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42116,739,625 - 116,801,084 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12116,686,636 - 116,699,453 (-)NCBI
Celera2107,508,914 - 107,569,241 (-)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prkci
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620961
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.