Gene: Prkci (protein kinase C, iota) Rattus norvegicus
Symbol: Prkci
Name: protein kinase C, iota
Description: ENCODES a protein that exhibits phospholipid binding (ortholog); protein kinase activity (ortholog); protein kinase C activity (ortholog); INVOLVED IN cell migration; cellular protein localization; cellular response to insulin stimulus; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; insulin signaling pathway; interleukin-1 signaling pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; abdominal obesity-metabolic syndrome (ortholog); Breast Neoplasms (ortholog); FOUND IN bicellular tight junction; cell leading edge; cytosol; INTERACTS WITH (RS)-amphetamine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aPKC-lambda/iota; atypical protein kinase C-lambda/iota; nPKC-iota; Pkcl; protein kinase C iota type; protein kinase C, lambda
Homo sapiens (human) : PRKCI (protein kinase C iota)  HGNC  Alliance
Mus musculus (house mouse) : Prkci (protein kinase C, iota)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkci (protein kinase C iota)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCI (protein kinase C iota)
Canis lupus familiaris (dog) : PRKCI (protein kinase C iota)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkci (protein kinase C iota)
Sus scrofa (pig) : PRKCI (protein kinase C iota)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02115,941,998 - 116,002,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02135,636,956 - 135,697,732 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42116,739,625 - 116,801,084 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12116,686,636 - 116,699,453 (-)NCBI
Celera2107,508,914 - 107,569,241 (-)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Prkci
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620961
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-02-05
Status: ACTIVE