Gene: Crlf2 (cytokine receptor-like factor 2) Rattus norvegicus
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Symbol: Crlf2
Name: cytokine receptor-like factor 2
Description: ENCODES a protein that exhibits cytokine activity; cytokine receptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); immunoglobulin secretion involved in immune response (ortholog); inflammatory response (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; ASSOCIATED WITH Acute Lymphoblastic Leukemia, with Lymphomatous Features (ortholog); autistic disorder (ortholog); precursor B lymphoblastic lymphoma/leukemia (ortholog); FOUND IN external side of plasma membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; aflatoxin B1; bisphenol A
AGR Description: Exhibits cytokine activity; predicted to be involved in several processes, including T-helper 2 cell cytokine production, cytokine-mediated signaling pathway, and immunoglobulin secretion involved in immune response; predicted to localize to the external side of plasma membrane and receptor complex; orthologous to human CRLF2 (cytokine receptor like factor 2).
Merged Description: Exhibits cytokine activity; predicted to be involved in several processes, including T-helper 2 cell cytokine production, cytokine-mediated signaling pathway, and immunoglobulin secretion involved in immune response; predicted to localize to the external side of plasma membrane and receptor complex; orthologous to human CRLF2 (cytokine receptor like factor 2); PARTICIPATES IN cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Crl2; thymic stromal lymphopoietin protein receptor; thymic stromal-derived lymphopoietin, receptor; Tpte2; transmembrane phosphoinositide 3-phosphatase and tensin homolog 2; TSLP receptor; Tslpr
Orthologs:
Homo sapiens (human) : CRLF2 (cytokine receptor like factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Crlf2 (cytokine receptor-like factor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crlf2 (cytokine receptor like factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CRLF2 (cytokine receptor like factor 2)
Canis lupus familiaris (dog) : CRLF2 (cytokine receptor like factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crlf2 (cytokine receptor like factor 2)
Sus scrofa (pig) : CRLF2 (cytokine receptor-like factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0141,456,843 - 1,461,543 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0141,459,624 - 1,464,324 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera14656,303 - 661,003 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Crlf2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621078
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.