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Gene: Ptprn2 (protein tyrosine phosphatase, receptor type N2) Rattus norvegicus
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Symbol: Ptprn2
Name: protein tyrosine phosphatase, receptor type N2
RGD ID: 61904
Description: Predicted to have protein tyrosine phosphatase activity. Involved in negative regulation of GTPase activity. Localizes to endoplasmic reticulum lumen; secretory vesicle; and terminal bouton. Human ortholog(s) of this gene implicated in prediabetes syndrome and type 1 diabetes mellitus. Orthologous to human PTPRN2 (protein tyrosine phosphatase receptor type N2); PARTICIPATES IN type 1 diabetes mellitus pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: phogrin; protein tyrosine phosphatase receptor-type N polypeptide 2; protein tyrosine phosphatase, receptor type, N polypeptide 2; protein tyrosine phosphatase, receptor-type, N polypeptide 2; PTP NE-6; PTPNE6; R-PTP-N2; receptor-type tyrosine-protein phosphatase N2
Orthologs:
Homo sapiens (human) : PTPRN2 (protein tyrosine phosphatase receptor type N2)  HGNC  Alliance
Mus musculus (house mouse) : Ptprn2 (protein tyrosine phosphatase, receptor type, N polypeptide 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ptprn2 (protein tyrosine phosphatase receptor type N2)
Pan paniscus (bonobo/pygmy chimpanzee) : PTPRN2 (protein tyrosine phosphatase receptor type N2)
Canis lupus familiaris (dog) : PTPRN2 (protein tyrosine phosphatase receptor type N2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ptprn2 (protein tyrosine phosphatase receptor type N2)
Sus scrofa (pig) : PTPRN2 (protein tyrosine phosphatase receptor type N2)
Chlorocebus sabaeus (African green monkey) : PTPRN2 (protein tyrosine phosphatase receptor type N2)
Heterocephalus glaber (naked mole-rat) : Ptprn2 (protein tyrosine phosphatase receptor type N2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06144,384,773 - 145,133,042 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6144,384,773 - 145,133,042 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06153,312,968 - 154,056,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,787,884 - 144,549,042 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16143,794,070 - 144,555,221 (+)NCBI
Celera6135,102,182 - 135,845,915 (+)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ptprn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61904
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.