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Gene: Ptprn2 (protein tyrosine phosphatase, receptor type N2) Rattus norvegicus
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Symbol: Ptprn2
Name: protein tyrosine phosphatase, receptor type N2
Description: Predicted to have protein tyrosine phosphatase activity. Involved in negative regulation of GTPase activity. Localizes to the cytoplasm and terminal bouton. Human ortholog(s) of this gene implicated in prediabetes syndrome and type 1 diabetes mellitus. Orthologous to human PTPRN2 (protein tyrosine phosphatase receptor type N2); PARTICIPATES IN type 1 diabetes mellitus pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: phogrin; protein tyrosine phosphatase receptor-type N polypeptide 2; protein tyrosine phosphatase, receptor type, N polypeptide 2; protein tyrosine phosphatase, receptor-type, N polypeptide 2; PTP NE-6; PTPNE6; R-PTP-N2; receptor-type tyrosine-protein phosphatase N2
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.06144,384,773 - 145,133,042 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06153,312,968 - 154,056,676 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46143,787,884 - 144,549,042 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.16143,794,070 - 144,555,221 (+)NCBI
Celera6135,102,182 - 135,845,915 (+)NCBICelera
Cytogenetic Map6q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ptprn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61904
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.