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Gene: Sem1 (SEM1, 26S proteasome complex subunit) Rattus norvegicus
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Symbol: Sem1
Name: SEM1, 26S proteasome complex subunit
Description: Predicted to be involved in double-strand break repair via homologous recombination. Predicted to colocalize with the integrator complex. Human ortholog(s) of this gene implicated in split hand-foot malformation 1. Orthologous to human SEM1 (SEM1 26S proteasome complex subunit); PARTICIPATES IN homologous recombination pathway of double-strand break repair; ubiquitin/proteasome degradation pathway; INTERACTS WITH bisphenol A; glyphosate; PhIP.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 26S proteasome complex subunit DSS1; Dss1; LOC680532; Shfm1; similar to 26 proteasome complex subunit DSS1 (Deleted in split hand/split foot protein 1) (Split hand/foot deleted protein 1 homolog); split hand/foot malformation (ectrodactyly) type 1
Orthologs:
Homo sapiens (human) : SEM1 (SEM1 26S proteasome complex subunit)  HGNC  Alliance
Mus musculus (house mouse) : Sem1 (SEM1, 26S proteasome complex subunit)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sem1 (SEM1 26S proteasome complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : SEM1 (SEM1, 26S proteasome complex subunit)
Canis lupus familiaris (dog) : SEM1 (SEM1, 26S proteasome complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sem1 (SEM1 26S proteasome complex subunit)
Sus scrofa (pig) : SEM1 (SEM1 26S proteasome complex subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0432,067,444 - 32,087,600 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0431,935,396 - 31,955,552 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4431,316,084 - 31,336,240 (-)NCBIRGSC3.4rn4RGSC3.4
Celera430,194,687 - 30,214,799 (-)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Sem1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1590628
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.