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Gene: Dkk2 (dickkopf WNT signaling pathway inhibitor 2) Rattus norvegicus
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Symbol: Dkk2
Name: dickkopf WNT signaling pathway inhibitor 2
RGD ID: 1308639
Description: Predicted to have co-receptor binding activity and receptor antagonist activity. Predicted to be involved in negative regulation of canonical Wnt signaling pathway and positive regulation of canonical Wnt signaling pathway. Predicted to localize to extracellular space. Orthologous to human DKK2 (dickkopf WNT signaling pathway inhibitor 2); PARTICIPATES IN Wnt signaling, canonical pathway; Wnt signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-Tetrachlorodibenzofuran; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: dickkopf 2 homolog; dickkopf 2 homolog (Xenopus laevis); dickkopf homolog 2; dickkopf homolog 2 (Xenopus laevis); dickkopf homolog 4; dickkopf homolog 4 (Xenopus laevis); dickkopf-related protein 2; Dkk4; LOC295445
Orthologs:
Homo sapiens (human) : DKK2 (dickkopf WNT signaling pathway inhibitor 2)  HGNC  Alliance
Mus musculus (house mouse) : Dkk2 (dickkopf WNT signaling pathway inhibitor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dkk2 (dickkopf WNT signaling pathway inhibitor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DKK2 (dickkopf WNT signaling pathway inhibitor 2)
Canis lupus familiaris (dog) : DKK2 (dickkopf WNT signaling pathway inhibitor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dkk2 (dickkopf WNT signaling pathway inhibitor 2)
Sus scrofa (pig) : DKK2 (dickkopf WNT signaling pathway inhibitor 2)
Chlorocebus sabaeus (African green monkey) : DKK2 (dickkopf WNT signaling pathway inhibitor 2)
Heterocephalus glaber (naked mole-rat) : Dkk2 (dickkopf WNT signaling pathway inhibitor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02237,148,918 - 237,240,883 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2237,148,941 - 237,241,350 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02255,689,579 - 255,781,478 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42229,542,203 - 229,634,156 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12229,529,344 - 229,619,963 (+)NCBI
Celera2212,811,245 - 212,902,656 (+)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dkk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1308639
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.