Ulbp1 (UL16 binding protein 1) - Rat Genome Database

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Gene: Ulbp1 (UL16 binding protein 1) Rattus norvegicus
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Symbol: Ulbp1
Name: UL16 binding protein 1
RGD ID: 7509852
Description: Predicted to enable natural killer cell lectin-like receptor binding activity and receptor ligand activity. Predicted to be involved in natural killer cell activation and natural killer cell mediated cytotoxicity. Predicted to act upstream of or within positive regulation of biosynthetic process; positive regulation of immune response; and positive regulation of leukocyte activation. Predicted to be located in cytosol and external side of plasma membrane. Orthologous to several human genes including ULBP2 (UL16 binding protein 2); RAET1E (retinoic acid early transcript 1E); and RAET1L (retinoic acid early transcript 1L); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; rotenone; silicon dioxide.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: histocompatibility antigen 60b-like; LOC102547056; retinoic acid early-inducible protein 1-gamma-like
RGD Orthologs
Human
Mouse
Bonobo
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813,506,106 - 3,527,982 (+)NCBIGRCr8
mRatBN7.211,694,255 - 1,716,160 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.011,181,301 - 1,200,526 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl11,180,932 - 1,220,916 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.012,908,847 - 2,910,387 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1393,918 - 415,841 (+)NCBICelera
Cytogenetic Map1p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
Additional References at PubMed
PMID:11239445   PMID:12645935   PMID:18676862  


Genomics

Comparative Map Data
Ulbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813,506,106 - 3,527,982 (+)NCBIGRCr8
mRatBN7.211,694,255 - 1,716,160 (+)NCBImRatBN7.2mRatBN7.2
Rnor_6.011,181,301 - 1,200,526 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl11,180,932 - 1,220,916 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.012,908,847 - 2,910,387 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1393,918 - 415,841 (+)NCBICelera
Cytogenetic Map1p13NCBI
ULBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386149,963,943 - 149,973,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6149,963,943 - 149,973,715 (+)EnsemblGRCh38hg38GRCh38
GRCh376150,285,079 - 150,294,851 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366150,326,836 - 150,336,539 (+)NCBINCBI36Build 36hg18NCBI36
Build 346150,377,256 - 150,386,958NCBI
Celera6151,019,759 - 151,029,462 (+)NCBICelera
Cytogenetic Map6q25.1NCBI
HuRef6147,850,624 - 147,860,327 (+)NCBIHuRef
CHM1_16150,549,752 - 150,559,455 (+)NCBICHM1_1
T2T-CHM13v2.06151,163,286 - 151,173,058 (+)NCBIT2T-CHM13v2.0
Ulbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39107,394,873 - 7,423,643 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl107,390,362 - 7,423,638 (-)EnsemblGRCm39 Ensembl
GRCm38107,444,873 - 7,473,641 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl107,440,362 - 7,473,638 (-)EnsemblGRCm38mm10GRCm38
MGSCv361021,913,473 - 21,944,572 (+)NCBIMGSCv36mm8
Celera107,404,171 - 7,432,757 (-)NCBICelera
Cytogenetic Map10A1NCBI
ULBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25170,004,951 - 170,014,501 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16167,865,912 - 167,882,972 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06147,798,494 - 147,811,888 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16152,477,350 - 152,486,911 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6152,477,350 - 152,486,911 (+)Ensemblpanpan1.1panPan2
LOC103240141
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11321,625,381 - 21,638,933 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1321,629,092 - 21,636,623 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366624161,719 - 71,242 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Ulbp1
465 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1124744506Rat
2298546Neuinf4Neuroinflammation QTL 45.1nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)1128736750Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1132356093Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1132356093Rat
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1132356093Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1578650Bmd6Bone mineral density QTL 612.2femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)150910843284926Rat
1578651Bmd7Bone mineral density QTL 714.2femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)150910843284926Rat
1578669Bss9Bone structure and strength QTL 96.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)150910843284926Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 18 8 6 1
Low 3 25 46 30 19 30 8 11 15 26 28 10 8
Below cutoff 10 10 10 57 1 6

Sequence


RefSeq Acc Id: ENSRNOT00000087443   ⟹   ENSRNOP00000073465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl11,180,932 - 1,220,916 (+)Ensembl
RefSeq Acc Id: XM_039098404   ⟹   XP_038954332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813,506,106 - 3,527,982 (+)NCBI
mRatBN7.211,694,255 - 1,716,160 (+)NCBI
RefSeq Acc Id: XR_005497168
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813,506,494 - 3,527,982 (+)NCBI
mRatBN7.211,694,688 - 1,716,160 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038954332 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: ENSRNOP00000073465   ⟸   ENSRNOT00000087443
RefSeq Acc Id: XP_038954332   ⟸   XM_039098404

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K5L0-F1-model_v2 AlphaFold A0A0G2K5L0 1-255 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:7509852 AgrOrtholog
BioCyc Gene G2FUF-62472 BioCyc
Ensembl Genes ENSRNOG00000061316 Ensembl
NCBI Gene LOC102547056 ENTREZGENE
PhenoGen Ulbp1 PhenoGen
RatGTEx ENSRNOG00000061316 RatGTEx


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-05-24 Ulbp1  UL16 binding protein 1  LOC102547056  retinoic acid early-inducible protein 1-gamma-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102547056  retinoic acid early-inducible protein 1-gamma-like      Symbol and Name status set to provisional 70820 PROVISIONAL