(+)-catechin multiple interactions ISO RGD:737091 6480464 Catechin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA] CTD PMID:29935159 (1->4)-beta-D-glucan multiple interactions ISO RGD:10734 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of HSD11B1 mRNA CTD PMID:36331819 (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:22265867 , PMID:26803847 (S)-nicotine affects expression EXP 6480464 Nicotine affects the expression of HSD11B1 mRNA CTD PMID:31972234 (S)-nicotine multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA] CTD PMID:26803847 (S)-nicotine increases expression ISO RGD:10734 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:21955143 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity EXP 6480464 2 more ... CTD PMID:23333641 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions EXP 6480464 2 more ... CTD PMID:19414516 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane decreases activity ISO RGD:737091 6480464 2 more ... CTD PMID:23333641 1,2-dimethylhydrazine multiple interactions ISO RGD:10734 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HSD11B1 mRNA CTD PMID:22206623 11-dehydrocorticosterone multiple interactions EXP 6480464 [HSD11B1 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone more ... CTD PMID:23814014 , PMID:26859423 11-dehydrocorticosterone affects response to substance ISO RGD:10734 6480464 HSD11B1 gene affects the susceptibility to 11-dehydrocorticosterone CTD PMID:16751407 11-dehydrocorticosterone increases metabolic processing ISO RGD:10734 6480464 HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone CTD PMID:16751407 11-dehydrocorticosterone affects abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form affects the abundance of 11-dehydrocorticosterone CTD PMID:25061560 11-dehydrocorticosterone increases metabolic processing EXP 6480464 HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone CTD PMID:23814014 11-dehydrocorticosterone increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone CTD PMID:26859423 17alpha-ethynylestradiol multiple interactions ISO RGD:10734 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSD11B1 mRNA CTD PMID:17942748 17alpha-ethynylestradiol multiple interactions ISO RGD:737091 6480464 Ethinyl Estradiol inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:28257955 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of HSD11B1 mRNA CTD PMID:29097150 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of HSD11B1 mRNA CTD PMID:12655037 more ... 17beta-estradiol decreases activity EXP 6480464 Estradiol results in decreased activity of HSD11B1 protein CTD PMID:23814014 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of HSD11B1 mRNA, Estradiol results in increased expression of HSD11B1 protein CTD PMID:32145629 17beta-estradiol multiple interactions ISO RGD:737091 6480464 [Estradiol co-treated with NAD] binds to HSD11B1 protein, [Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with Estradiol] results in increased expression of HSD11B1 protein CTD PMID:23275455 , PMID:25526675 17beta-estradiol decreases expression ISO RGD:10734 6480464 Estradiol results in decreased expression of HSD11B1 mRNA CTD PMID:19484750 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:33581290 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2 more ... CTD PMID:33581290 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10734 6480464 Tetrachlorodibenzodioxin results in increased expression of HSD11B1 mRNA CTD PMID:17035482 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of HSD11B1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737091 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSD11B1 mRNA CTD PMID:21998131 , PMID:23669205 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10734 6480464 Tetrachlorodibenzodioxin affects the expression of HSD11B1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of HSD11B1 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSD11B1 mRNA CTD PMID:16960034 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10734 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSD11B1 mRNA, Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to HSD11B1 promoter] CTD PMID:17942748 , PMID:19654925 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10734 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSD11B1 mRNA CTD PMID:16960034 2,3,7,8-Tetrachlorodibenzofuran increases expression EXP 6480464 2 more ... CTD PMID:32109520 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of HSD11B1 mRNA CTD PMID:21513799 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of HSD11B1 mRNA CTD PMID:21346803 2-hydroxypropanoic acid decreases expression ISO RGD:737091 6480464 Lactic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:30851411 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3,3',4,4',5-pentachlorobiphenyl increases expression ISO RGD:737091 6480464 3 more ... CTD PMID:35618242 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO RGD:10734 6480464 3 more ... CTD PMID:19467301 3,4-methylenedioxymethamphetamine increases expression EXP 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of HSD11B1 mRNA CTD PMID:30071829 3,7-dihydropurine-6-thione increases expression EXP 6480464 Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:737091 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of HSD11B1 mRNA more ... CTD PMID:19186324 , PMID:28628672 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanic acid increases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in increased abundance of 7-ketodeoxycholic acid CTD PMID:25061560 4,4'-sulfonyldiphenol increases expression ISO RGD:737091 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of HSD11B1 mRNA, bis(4-hydroxyphenyl)sulfone results in increased expression of HSD11B1 protein CTD PMID:27685785 , PMID:34186270 4,4'-sulfonyldiphenol multiple interactions ISO RGD:737091 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of HSD11B1 mRNA CTD PMID:28628672 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases reduction ISO RGD:737091 6480464 HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone CTD PMID:28257955 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions ISO RGD:737091 6480464 drospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] more ... CTD PMID:28257955 4-hydroxyphenyl retinamide decreases expression ISO RGD:10734 6480464 Fenretinide results in decreased expression of HSD11B1 mRNA CTD PMID:28973697 4-nonylphenol decreases activity ISO RGD:737091 6480464 4-nonylphenol results in decreased activity of HSD11B1 protein CTD PMID:16184081 4-tert-Octylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of HSD11B1 mRNA CTD PMID:17011747 4-tert-Octylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of HSD11B1 mRNA CTD PMID:17011747 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of HSD11B1 mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression ISO RGD:10734 6480464 Propylthiouracil results in decreased expression of HSD11B1 mRNA CTD PMID:36706583 6alpha-methylprednisolone decreases expression ISO RGD:737091 6480464 Methylprednisolone results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 7-oxolithocholic acid increases reduction ISO RGD:737091 6480464 HSD11B1 protein results in increased reduction of 7-ketolithocholic acid CTD PMID:21453287 7-oxolithocholic acid multiple interactions ISO RGD:737091 6480464 [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Chenodeoxycholic Acid, [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Ursodeoxycholic Acid CTD PMID:21453287 8-Br-cAMP multiple interactions ISO RGD:737091 6480464 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA] more ... CTD PMID:23275455 9-cis-retinoic acid decreases expression ISO RGD:737091 6480464 Alitretinoin results in decreased expression of HSD11B1 mRNA CTD PMID:15982314 acetamide decreases expression EXP 6480464 acetamide results in decreased expression of HSD11B1 mRNA CTD PMID:31881176 aflatoxin B1 affects expression ISO RGD:737091 6480464 Aflatoxin B1 affects the expression of HSD11B1 protein CTD PMID:20106945 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of HSD11B1 mRNA CTD PMID:33354967 aflatoxin B1 decreases expression ISO RGD:737091 6480464 Aflatoxin B1 results in decreased expression of HSD11B1 mRNA CTD PMID:22100608 , PMID:27153756 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HSD11B1 mRNA CTD PMID:16483693 androstane-3,17-diol multiple interactions ISO RGD:737091 6480464 [Androstane-3, 17-diol co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 androstane-3,17-diol affects binding ISO RGD:737091 6480464 Androstane-3, 17-diol binds to HSD11B1 protein CTD PMID:25526675 arsenic acid affects methylation ISO RGD:10734 6480464 arsenic acid affects the methylation of HSD11B1 gene CTD PMID:26855884 atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of HSD11B1 mRNA CTD PMID:36841081 azathioprine decreases expression ISO RGD:737091 6480464 Azathioprine results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 benzamide decreases activity ISO RGD:737091 6480464 benzamide analog results in decreased activity of HSD11B1 protein CTD PMID:18553955 more ... benzo[a]pyrene decreases expression ISO RGD:737091 6480464 Benzo(a)pyrene results in decreased expression of HSD11B1 mRNA CTD PMID:20106945 , PMID:32234424 benzo[a]pyrene increases methylation ISO RGD:737091 6480464 Benzo(a)pyrene results in increased methylation of HSD11B1 5' UTR, Benzo(a)pyrene results in increased methylation of HSD11B1 promoter CTD PMID:27901495 benzo[a]pyrene decreases expression ISO RGD:10734 6480464 Benzo(a)pyrene results in decreased expression of HSD11B1 mRNA CTD PMID:23735875 benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with 1 more ... CTD PMID:18711122 benzo[a]pyrene affects expression ISO RGD:10734 6480464 Benzo(a)pyrene affects the expression of HSD11B1 mRNA CTD PMID:22342234 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of HSD11B1 mRNA CTD PMID:21839799 benzo[a]pyrene diol epoxide I affects expression ISO RGD:737091 6480464 7 more ... CTD PMID:20382639 benzo[b]fluoranthene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with benzo(b)fluoranthene] affects the expression of HSD11B1 mRNA CTD PMID:18711122 bezafibrate decreases activity ISO RGD:10734 6480464 Bezafibrate results in decreased activity of HSD11B1 protein CTD PMID:17190905 bezafibrate decreases expression ISO RGD:10734 6480464 Bezafibrate results in decreased expression of HSD11B1 mRNA CTD PMID:17190905 bis(2-chloroethyl) sulfide increases expression ISO RGD:737091 6480464 Mustard Gas results in increased expression of HSD11B1 mRNA CTD PMID:25102026 bis(2-ethylhexyl) adipate decreases activity ISO RGD:737091 6480464 dioctyl adipate results in decreased activity of HSD11B1 protein CTD PMID:16184081 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:10734 6480464 Diethylhexyl Phthalate results in decreased expression of HSD11B1 mRNA CTD PMID:19245819 bisphenol A increases methylation ISO RGD:737091 6480464 bisphenol A results in increased methylation of HSD11B1 gene CTD PMID:22576693 bisphenol A affects binding ISO RGD:737091 6480464 bisphenol A binds to HSD11B1 protein CTD PMID:34706627 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of HSD11B1 mRNA, bisphenol A results in increased expression of HSD11B1 protein CTD PMID:29524480 , PMID:32145629 bisphenol A decreases expression EXP 6480464 bisphenol A analog results in decreased expression of HSD11B1 mRNA more ... CTD PMID:30816183 , PMID:35427877 bisphenol A increases methylation ISO RGD:10734 6480464 bisphenol A results in increased methylation of HSD11B1 promoter CTD PMID:27312807 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of HSD11B1 gene CTD PMID:28505145 bisphenol A increases expression ISO RGD:737091 6480464 bisphenol A results in increased expression of HSD11B1 mRNA CTD PMID:23090578 , PMID:27685785 bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of HSD11B1 mRNA CTD PMID:25181051 , PMID:30903817 bisphenol A increases expression ISO RGD:10734 6480464 bisphenol A results in increased expression of HSD11B1 mRNA CTD PMID:26063408 more ... bisphenol A decreases activity ISO RGD:737091 6480464 bisphenol A results in decreased activity of HSD11B1 protein CTD PMID:23069880 bisphenol A decreases activity EXP 6480464 bisphenol A results in decreased activity of HSD11B1 protein CTD PMID:23069880 bisphenol A increases activity ISO RGD:737091 6480464 bisphenol A results in increased activity of HSD11B1 protein CTD PMID:23090578 bisphenol A decreases expression ISO RGD:737091 6480464 bisphenol A results in decreased expression of HSD11B1 mRNA, bisphenol A results in decreased expression of HSD11B1 protein CTD PMID:22576693 , PMID:34186270 bisphenol A multiple interactions ISO RGD:737091 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of HSD11B1 gene, Mifepristone inhibits the reaction [bisphenol A results in increased expression of HSD11B1 mRNA] CTD PMID:23090578 , PMID:31601247 Bisphenol B increases expression EXP 6480464 bisphenol B results in increased expression of HSD11B1 protein CTD PMID:33940105 Bisphenol B increases expression ISO RGD:737091 6480464 bisphenol B results in increased expression of HSD11B1 protein CTD PMID:34186270 Butylbenzyl phthalate increases expression EXP 6480464 butylbenzyl phthalate results in increased expression of HSD11B1 protein CTD PMID:31319113 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of HSD11B1 mRNA CTD PMID:33453195 caffeine increases expression EXP 6480464 Caffeine results in increased expression of HSD11B1 mRNA CTD PMID:22583948 more ... calcitriol multiple interactions ISO RGD:737091 6480464 [Calcitriol co-treated with Cortisone] results in increased expression of HSD11B1 mRNA CTD PMID:19918113 calcitriol affects expression ISO RGD:737091 6480464 Calcitriol affects the expression of HSD11B1 protein CTD PMID:19918113 CARBENOXOLONE multiple interactions ISO RGD:10734 6480464 Carbenoxolone inhibits the reaction [Lipopolysaccharides results in increased expression of HSD11B1 mRNA] CTD PMID:27523796 CARBENOXOLONE decreases activity ISO RGD:737091 6480464 Carbenoxolone results in decreased activity of HSD11B1 protein CTD PMID:24135201 CARBENOXOLONE decreases activity ISO RGD:10734 6480464 Carbenoxolone results in decreased activity of HSD11B1 protein CTD PMID:24135201 CARBENOXOLONE decreases activity EXP 6480464 Carbenoxolone results in decreased activity of HSD11B1 protein CTD PMID:23814014 carbon nanotube increases expression ISO RGD:737091 6480464 Nanotubes, Carbon results in increased expression of HSD11B1 mRNA CTD PMID:29348435 chenodeoxycholic acid decreases activity ISO RGD:737091 6480464 Chenodeoxycholic Acid results in decreased activity of HSD11B1 protein CTD PMID:10664531 chenodeoxycholic acid increases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in increased abundance of Chenodeoxycholic Acid CTD PMID:25061560 chenodeoxycholic acid multiple interactions ISO RGD:737091 6480464 [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Chenodeoxycholic Acid CTD PMID:21453287 cholic acid increases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in increased abundance of Cholic Acid CTD PMID:25061560 chromium atom increases expression EXP 6480464 Chromium deficiency results in increased expression of HSD11B1 mRNA CTD PMID:19846803 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of HSD11B1 protein CTD PMID:22023808 clofibrate decreases expression ISO RGD:10734 6480464 Clofibrate results in decreased expression of HSD11B1 mRNA CTD PMID:17585979 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of HSD11B1 mRNA CTD PMID:12851107 clofibrate multiple interactions ISO RGD:10734 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA] CTD PMID:17585979 clofibric acid decreases expression EXP 6480464 Clofibric Acid results in decreased expression of HSD11B1 mRNA CTD PMID:15833021 clofibric acid multiple interactions EXP 6480464 [Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of HSD11B1 mRNA CTD PMID:15833021 corticosterone multiple interactions EXP 6480464 [HSD11B1 protein results in increased oxidation of Corticosterone] which results in increased chemical synthesis of 11-dehydrocorticosterone more ... CTD PMID:23814014 , PMID:26859423 corticosterone multiple interactions ISO RGD:10734 6480464 [[trimethyltin chloride results in increased abundance of trimethyltin] which co-treated with Corticosterone] results in increased expression of HSD11B1 mRNA more ... CTD PMID:30993381 corticosterone increases oxidation EXP 6480464 HSD11B1 protein results in increased oxidation of Corticosterone CTD PMID:26859423 corticosterone decreases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in decreased abundance of Corticosterone CTD PMID:25061560 corticosterone increases expression EXP 6480464 Corticosterone results in increased expression of HSD11B1 mRNA CTD PMID:15755911 corticosterone increases chemical synthesis ISO RGD:10734 6480464 HSD11B1 protein results in increased chemical synthesis of Corticosterone CTD PMID:16751407 corticosterone increases chemical synthesis EXP 6480464 HSD11B1 protein results in increased chemical synthesis of Corticosterone CTD PMID:23814014 cortisol multiple interactions ISO RGD:737091 6480464 [HSD11B1 protein results in increased metabolism of Ketosteroids] which results in increased chemical synthesis of Hydrocortisone more ... CTD PMID:17761898 more ... cortisol affects expression ISO RGD:737091 6480464 Hydrocortisone affects the expression of HSD11B1 mRNA CTD PMID:30528684 cortisol increases oxidation ISO RGD:737091 6480464 HSD11B1 protein results in increased oxidation of Hydrocortisone CTD PMID:26859423 cortisol multiple interactions EXP 6480464 [HSD11B1 protein affects the susceptibility to Hydrocortisone] which results in decreased activity of NFE2L2 protein CTD PMID:22606287 cortisol affects response to substance EXP 6480464 HSD11B1 protein affects the susceptibility to Hydrocortisone CTD PMID:22606287 cortisol increases chemical synthesis ISO RGD:737091 6480464 HSD11B1 protein results in increased chemical synthesis of Hydrocortisone CTD PMID:16054388 more ... cortisol increases expression ISO RGD:737091 6480464 Hydrocortisone results in increased expression of HSD11B1 more ... CTD PMID:16054388 more ... cortisol increases activity ISO RGD:737091 6480464 Hydrocortisone results in increased activity of HSD11B1 protein CTD PMID:20410225 cortisol affects oxidation ISO RGD:737091 6480464 HSD11B1 protein affects the oxidation of Hydrocortisone CTD PMID:17761898 cortisone multiple interactions ISO RGD:737091 6480464 [Calcitriol co-treated with Cortisone] results in increased expression of HSD11B1 mRNA more ... CTD PMID:19918113 more ... cortisone increases expression EXP 6480464 Cortisone results in increased expression of HSD11B1 mRNA CTD PMID:30993381 cortisone increases reduction ISO RGD:737091 6480464 HSD11B1 protein results in increased reduction of Cortisone CTD PMID:26859423 cortisone affects response to substance EXP 6480464 HSD11B1 protein affects the susceptibility to Cortisone CTD PMID:22606287 cortisone increases expression ISO RGD:10734 6480464 Cortisone results in increased expression of HSD11B1 mRNA CTD PMID:24135201 cortisone multiple interactions EXP 6480464 [HSD11B1 protein affects the susceptibility to Cortisone] which results in decreased activity of NFE2L2 protein more ... CTD PMID:22606287 , PMID:30993381 cortisone multiple interactions ISO RGD:10734 6480464 2-(3-benzoyl)-4-hydroxy-1 more ... CTD PMID:21315688 cortisone increases metabolic processing ISO RGD:737091 6480464 HSD11B1 protein results in increased metabolism of Cortisone CTD PMID:16751407 cortisone affects metabolic processing ISO RGD:737091 6480464 HSD11B1 protein affects the metabolism of Cortisone CTD PMID:16054388 crocidolite asbestos increases expression ISO RGD:737091 6480464 Asbestos, Crocidolite results in increased expression of HSD11B1 mRNA CTD PMID:25351596 crocidolite asbestos decreases expression ISO RGD:10734 6480464 Asbestos, Crocidolite results in decreased expression of HSD11B1 mRNA CTD PMID:29279043 Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of HSD11B1 mRNA CTD PMID:26577399 cyclosporin A decreases expression ISO RGD:737091 6480464 Cyclosporine results in decreased expression of HSD11B1 mRNA CTD PMID:20106945 cyhalothrin decreases expression EXP 6480464 cyhalothrin results in decreased expression of HSD11B1 mRNA, cyhalothrin results in decreased expression of HSD11B1 protein CTD PMID:30029170 deoxycholic acid increases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in increased abundance of Deoxycholic Acid CTD PMID:25061560 dexamethasone multiple interactions ISO RGD:737091 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of HSD11B1 mRNA more ... CTD PMID:19186324 more ... dexamethasone increases expression ISO RGD:10734 6480464 Dexamethasone results in increased expression of HSD11B1 mRNA CTD PMID:19344079 , PMID:22733784 dexamethasone increases expression ISO RGD:737091 6480464 Dexamethasone results in increased expression of HSD11B1 mRNA CTD PMID:19853017 dexamethasone affects expression EXP 6480464 Dexamethasone affects the expression of HSD11B1 mRNA CTD PMID:15102944 dextran sulfate multiple interactions ISO RGD:10734 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HSD11B1 mRNA CTD PMID:29950665 dextran sulfate increases expression ISO RGD:10734 6480464 Dextran Sulfate results in increased expression of HSD11B1 mRNA CTD PMID:35093514 Di-n-hexyl phthalate decreases expression EXP 6480464 di-n-hexyl phthalate results in decreased expression of HSD11B1 protein CTD PMID:32693021 dibenz[a,h]anthracene multiple interactions EXP 6480464 [1 more ... CTD PMID:18711122 dibenzo[a,l]pyrene multiple interactions EXP 6480464 [1 more ... CTD PMID:18711122 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of HSD11B1 protein CTD PMID:19815848 dibutyl phthalate decreases expression EXP 6480464 Dibutyl Phthalate results in decreased expression of HSD11B1 mRNA CTD PMID:28528174 dichloroacetic acid decreases expression ISO RGD:10734 6480464 Dichloroacetic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:28962523 Dicyclohexyl phthalate decreases expression EXP 6480464 dicyclohexyl phthalate results in decreased expression of HSD11B1 mRNA, dicyclohexyl phthalate results in decreased expression of HSD11B1 protein CTD PMID:30391266 diethyl hydrogen phosphate decreases expression EXP 6480464 diethyl phosphate results in decreased expression of HSD11B1 mRNA CTD PMID:35777568 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of HSD11B1 mRNA CTD PMID:17011747 disulfiram multiple interactions ISO RGD:737091 6480464 [Disulfiram co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 diuron increases expression EXP 6480464 Diuron results in increased expression of HSD11B1 mRNA CTD PMID:21551480 doxorubicin decreases expression ISO RGD:737091 6480464 Doxorubicin results in decreased expression of HSD11B1 mRNA CTD PMID:29803840 drospirenone multiple interactions ISO RGD:737091 6480464 drospirenone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:28257955 ethanol decreases expression ISO RGD:10734 6480464 Ethanol results in decreased expression of HSD11B1 mRNA CTD PMID:21955143 ethanol increases expression ISO RGD:10734 6480464 Ethanol results in increased expression of HSD11B1 mRNA CTD PMID:30319688 ethanol multiple interactions EXP 6480464 Ethanol affects the reaction [Dietary Fats affects the expression of HSD11B1 mRNA] CTD PMID:31811911 ethanol affects expression EXP 6480464 Ethanol affects the expression of HSD11B1 mRNA CTD PMID:31039417 ethanol increases expression EXP 6480464 Ethanol results in increased expression of HSD11B1 mRNA CTD PMID:26188107 , PMID:32535229 fenofibrate increases expression ISO RGD:737091 6480464 Fenofibrate results in increased expression of HSD11B1 mRNA CTD PMID:25572481 fenthion increases expression ISO RGD:10734 6480464 Fenthion results in increased expression of HSD11B1 mRNA CTD PMID:34813904 fipronil multiple interactions ISO RGD:737091 6480464 [fipronil co-treated with DEET] results in decreased expression of HSD11B1 mRNA CTD PMID:27091632 fluoranthene multiple interactions EXP 6480464 [1 more ... CTD PMID:18711122 folic acid multiple interactions ISO RGD:10734 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of HSD11B1 mRNA CTD PMID:22206623 fulvestrant multiple interactions ISO RGD:737091 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of HSD11B1 gene CTD PMID:31601247 fumonisin B1 decreases expression ISO RGD:10734 6480464 fumonisin B1 results in decreased expression of HSD11B1 mRNA CTD PMID:16221962 furan increases expression EXP 6480464 furan results in increased expression of HSD11B1 mRNA CTD PMID:26194646 furosemide decreases activity EXP 6480464 Furosemide results in decreased activity of HSD11B1 protein CTD PMID:11749789 genistein decreases expression EXP 6480464 Genistein results in decreased expression of HSD11B1 mRNA CTD PMID:21782745 genistein decreases expression ISO RGD:10734 6480464 Genistein results in decreased expression of HSD11B1 mRNA CTD PMID:32186404 glycochenodeoxycholic acid decreases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in decreased abundance of Glycochenodeoxycholic Acid CTD PMID:25061560 glycolithocholic acid decreases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in decreased abundance of glycolithocholic acid CTD PMID:25061560 glycyrrhetinate decreases activity ISO RGD:10734 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 glycyrrhetinate decreases activity ISO RGD:737091 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 glycyrrhetinic acid decreases activity ISO RGD:737091 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 glycyrrhetinic acid decreases activity ISO RGD:10734 6480464 18alpha-glycyrrhetinic acid results in decreased activity of HSD11B1 protein CTD PMID:24135201 herbicide multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of HSD11B1 mRNA CTD PMID:25588985 hyodeoxycholic acid increases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in increased abundance of hyodeoxycholic acid CTD PMID:25061560 indometacin multiple interactions ISO RGD:737091 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in increased expression of HSD11B1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of HSD11B1 mRNA CTD PMID:28628672 inulin multiple interactions ISO RGD:10734 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of HSD11B1 mRNA CTD PMID:36331819 isotretinoin decreases expression ISO RGD:737091 6480464 Isotretinoin results in decreased expression of HSD11B1 mRNA CTD PMID:15982314 , PMID:20436886 kainic acid decreases expression ISO RGD:10734 6480464 Kainic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:17997037 ketamine increases expression EXP 6480464 Ketamine results in increased expression of HSD11B1 mRNA CTD PMID:20080153 lipopolysaccharide multiple interactions ISO RGD:10734 6480464 2-(3-benzoyl)-4-hydroxy-1 more ... CTD PMID:27523796 lipopolysaccharide increases expression ISO RGD:10734 6480464 Lipopolysaccharides results in increased expression of HSD11B1 mRNA CTD PMID:16847310 , PMID:27523796 manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of HSD11B1 mRNA CTD PMID:28801915 medroxyprogesterone acetate multiple interactions ISO RGD:737091 6480464 [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of and results in increased activity of HSD11B1 protein, [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA CTD PMID:23275455 mercaptopurine increases expression EXP 6480464 Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 methidathion increases expression ISO RGD:10734 6480464 methidathion results in increased expression of HSD11B1 mRNA CTD PMID:34813904 methotrexate increases expression ISO RGD:737091 6480464 Methotrexate results in increased expression of HSD11B1 mRNA CTD PMID:17400583 methotrexate decreases expression ISO RGD:737091 6480464 Methotrexate results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 methoxychlor decreases activity ISO RGD:737091 6480464 Methoxychlor results in decreased activity of HSD11B1 protein CTD PMID:23333641 metyrapone decreases activity ISO RGD:737091 6480464 Metyrapone results in decreased activity of HSD11B1 protein CTD PMID:10664531 mifepristone multiple interactions ISO RGD:737091 6480464 [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]] more ... CTD PMID:22606287 more ... mifepristone multiple interactions ISO RGD:10734 6480464 Mifepristone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]] CTD PMID:30993381 mifepristone multiple interactions EXP 6480464 [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [HSD11B1 protein results in decreased activity of NFE2L2 protein] CTD PMID:22606287 monosodium L-glutamate multiple interactions ISO RGD:10734 6480464 [Sodium Glutamate co-treated with Trans Fatty Acids] results in decreased expression of HSD11B1 mRNA CTD PMID:19001666 morphine decreases expression ISO RGD:10734 6480464 Morphine results in decreased expression of HSD11B1 mRNA CTD PMID:21955143 N,N-diethyl-m-toluamide multiple interactions ISO RGD:737091 6480464 [fipronil co-treated with DEET] results in decreased expression of HSD11B1 mRNA CTD PMID:27091632 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [2 more ... CTD PMID:33581290 N-nitrosodiethylamine multiple interactions EXP 6480464 [Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of HSD11B1 mRNA CTD PMID:15833021 N-Nitrosopyrrolidine increases expression ISO RGD:737091 6480464 N-Nitrosopyrrolidine results in increased expression of HSD11B1 mRNA CTD PMID:32234424 NAD zwitterion multiple interactions ISO RGD:737091 6480464 [Androstane-3 more ... CTD PMID:25526675 NAD(+) multiple interactions ISO RGD:737091 6480464 [Androstane-3 more ... CTD PMID:25526675 NADP zwitterion increases oxidation ISO RGD:737091 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 NADP zwitterion multiple interactions ISO RGD:737091 6480464 NADP binds to and results in increased activity of HSD11B1 protein CTD PMID:25526675 NADP zwitterion increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 NADP zwitterion increases reduction ISO RGD:737091 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 NADP zwitterion increases oxidation EXP 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 NADP zwitterion multiple interactions EXP 6480464 Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP] CTD PMID:26859423 NADP(+) increases oxidation EXP 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 NADP(+) multiple interactions ISO RGD:737091 6480464 NADP binds to and results in increased activity of HSD11B1 protein CTD PMID:25526675 NADP(+) increases oxidation ISO RGD:737091 6480464 HSD11B1 protein results in increased oxidation of NADP CTD PMID:26859423 NADP(+) increases reduction ISO RGD:737091 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 NADP(+) increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of NADP CTD PMID:26859423 NADP(+) multiple interactions EXP 6480464 Ziram inhibits the reaction [HSD11B1 protein results in increased oxidation of NADP] CTD PMID:26859423 nickel atom decreases expression ISO RGD:737091 6480464 Nickel results in decreased expression of HSD11B1 mRNA CTD PMID:24768652 nicotine increases expression ISO RGD:10734 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:21955143 nicotine affects expression EXP 6480464 Nicotine affects the expression of HSD11B1 mRNA CTD PMID:31972234 nicotine multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA] CTD PMID:26803847 nicotine increases expression EXP 6480464 Nicotine results in increased expression of HSD11B1 mRNA CTD PMID:22265867 , PMID:26803847 nitrofen increases expression EXP 6480464 nitrofen results in increased expression of HSD11B1 mRNA CTD PMID:33484710 Nonylphenol multiple interactions EXP 6480464 nonylphenol results in increased expression of and results in increased activity of HSD11B1 protein CTD PMID:22765982 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of HSD11B1 mRNA CTD PMID:25729387 oxaliplatin increases expression EXP 6480464 oxaliplatin results in increased expression of HSD11B1 mRNA CTD PMID:25729387 oxycodone decreases expression EXP 6480464 Oxycodone results in decreased expression of HSD11B1 mRNA CTD PMID:23439660 ozone multiple interactions ISO RGD:737091 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of HSD11B1 mRNA CTD PMID:26035830 ozone multiple interactions ISO RGD:10734 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of HSD11B1 mRNA, [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of HSD11B1 mRNA CTD PMID:34911549 p-tert-Amylphenol decreases expression EXP 6480464 4-tert-octylphenol results in decreased expression of HSD11B1 mRNA CTD PMID:17011747 p-tert-Amylphenol increases expression EXP 6480464 4-tert-octylphenol results in increased expression of HSD11B1 mRNA CTD PMID:17011747 p-toluidine increases expression EXP 6480464 4-toluidine results in increased expression of HSD11B1 mRNA CTD PMID:27638505 paracetamol multiple interactions ISO RGD:10734 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HSD11B1 mRNA] CTD PMID:17585979 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of HSD11B1 mRNA CTD PMID:33387578 paracetamol decreases expression ISO RGD:737091 6480464 Acetaminophen results in decreased expression of HSD11B1 mRNA CTD PMID:29067470 paracetamol affects expression ISO RGD:10734 6480464 Acetaminophen affects the expression of HSD11B1 mRNA CTD PMID:17562736 paraquat increases expression EXP 6480464 Paraquat results in increased expression of HSD11B1 mRNA CTD PMID:18198484 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of HSD11B1 mRNA, Paraquat results in decreased expression of HSD11B1 protein CTD PMID:31128353 parathion increases expression ISO RGD:10734 6480464 Parathion results in increased expression of HSD11B1 mRNA CTD PMID:34813904 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of HSD11B1 mRNA, perfluorododecanoic acid results in decreased expression of HSD11B1 protein CTD PMID:30489073 , PMID:33774092 perfluorononanoic acid multiple interactions EXP 6480464 [perfluoro-n-nonanoic acid co-treated with [Phytochemicals co-treated with Environmental Pollutants co-treated with Food Preservatives co-treated with Plasticizers co-treated with Sunscreening Agents co-treated with Insecticides co-treated with Fungicides, Industrial co-treated with Herbicides]] results in decreased expression of HSD11B1 mRNA CTD PMID:25588985 perfluorooctane-1-sulfonic acid decreases activity ISO RGD:737091 6480464 perfluorooctane sulfonic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:10734 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of HSD11B1 mRNA more ... CTD PMID:36331819 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:737091 6480464 perfluorooctane sulfonic acid inhibits the reaction [Hydrocortisone results in increased expression of HSD11B1] CTD PMID:27288094 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:737091 6480464 perfluorooctane sulfonic acid results in decreased expression of HSD11B1 CTD PMID:27288094 perfluorooctane-1-sulfonic acid decreases activity EXP 6480464 perfluorooctane sulfonic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 perfluorooctanoic acid decreases expression ISO RGD:10734 6480464 perfluorooctanoic acid results in decreased expression of HSD11B1 mRNA CTD PMID:17681415 , PMID:30711707 perfluorooctanoic acid decreases activity EXP 6480464 perfluorooctanoic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 perfluorooctanoic acid decreases activity ISO RGD:737091 6480464 perfluorooctanoic acid results in decreased activity of HSD11B1 protein CTD PMID:22178014 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of HSD11B1 mRNA, perfluorooctanoic acid results in decreased expression of HSD11B1 protein CTD PMID:16221955 more ... perfluoroundecanoic acid decreases expression EXP 6480464 perfluoroundecanoic acid results in decreased expression of HSD11B1 mRNA, perfluoroundecanoic acid results in decreased expression of HSD11B1 protein CTD PMID:33549592 , PMID:35143807 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of HSD11B1 mRNA CTD PMID:19162173 phorbol 13-acetate 12-myristate increases activity EXP 6480464 Tetradecanoylphorbol Acetate results in increased activity of HSD11B1 protein CTD PMID:16533503 phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of HSD11B1 mRNA CTD PMID:16533503 piperonyl butoxide decreases expression EXP 6480464 Piperonyl Butoxide results in decreased expression of HSD11B1 mRNA CTD PMID:22484513 pirinixic acid multiple interactions ISO RGD:10734 6480464 [pirinixic acid co-treated with PPARA] results in decreased expression of HSD11B1 mRNA, PPARA protein promotes the reaction [pirinixic acid results in decreased expression of HSD11B1 mRNA] CTD PMID:20059764 , PMID:20813756 pirinixic acid decreases expression ISO RGD:10734 6480464 pirinixic acid results in decreased expression of HSD11B1 mRNA CTD PMID:11798191 more ... pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of HSD11B1 mRNA CTD PMID:19162173 , PMID:22484513 piroxicam decreases expression ISO RGD:737091 6480464 Piroxicam results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 prednisolone decreases expression ISO RGD:737091 6480464 Prednisolone results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of HSD11B1 mRNA CTD PMID:19162173 progesterone affects expression EXP 6480464 Progesterone affects the expression of HSD11B1 mRNA, Progesterone affects the expression of HSD11B1 protein CTD PMID:19208548 progesterone multiple interactions ISO RGD:737091 6480464 4'-cyanobiphenyl-4-sulfonic acid (6-aminopyridin-2-yl)amide inhibits the reaction [[Progesterone co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased expression of HSD11B1 mRNA] more ... CTD PMID:23275455 , PMID:28257955 progesterone increases expression EXP 6480464 Progesterone results in increased expression of HSD11B1 mRNA CTD PMID:20726854 progesterone increases expression ISO RGD:737091 6480464 Progesterone results in increased expression of HSD11B1 mRNA CTD PMID:21795739 Propiverine affects binding EXP 6480464 propiverine binds to HSD11B1 protein CTD PMID:29273565 prostaglandin E2 multiple interactions ISO RGD:737091 6480464 6-isopropoxy-9-oxoxanthene-2-carboxylic acid inhibits the reaction [Dinoprostone results in increased activity of HSD11B1 protein] more ... CTD PMID:17761898 prostaglandin E2 increases activity ISO RGD:737091 6480464 Dinoprostone results in increased activity of HSD11B1 protein CTD PMID:17761898 purine-6-thiol increases expression EXP 6480464 Mercaptopurine results in increased expression of HSD11B1 mRNA CTD PMID:23358152 pyrazinecarboxamide increases expression EXP 6480464 Pyrazinamide results in increased expression of HSD11B1 mRNA CTD PMID:22431067 quercetin multiple interactions ISO RGD:737091 6480464 [Quercetin co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 rac-lactic acid decreases expression ISO RGD:737091 6480464 Lactic Acid results in decreased expression of HSD11B1 mRNA CTD PMID:30851411 resveratrol decreases activity EXP 6480464 resveratrol results in decreased activity of HSD11B1 protein CTD PMID:23814014 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [HSD11B1 protein results in increased chemical synthesis of Corticosterone], Resveratrol inhibits the reaction [HSD11B1 protein results in increased metabolism of 11-dehydrocorticosterone] CTD PMID:23814014 resveratrol decreases activity ISO RGD:10734 6480464 resveratrol results in decreased activity of HSD11B1 protein CTD PMID:23814014 SB 203580 multiple interactions ISO RGD:10734 6480464 SB 203580 inhibits the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA] CTD PMID:30993381 serpentine asbestos increases expression ISO RGD:737091 6480464 Asbestos, Serpentine results in increased expression of HSD11B1 mRNA CTD PMID:24160326 serpentine asbestos decreases expression ISO RGD:10734 6480464 Asbestos, Serpentine results in decreased expression of HSD11B1 mRNA CTD PMID:16251409 silicon dioxide increases expression ISO RGD:737091 6480464 Silicon Dioxide results in increased expression of HSD11B1 mRNA CTD PMID:25351596 sodium arsenate decreases glycosylation ISO RGD:10734 6480464 sodium arsenate results in decreased glycosylation of HSD11B1 protein CTD PMID:22960421 sodium arsenite decreases expression ISO RGD:10734 6480464 sodium arsenite results in decreased expression of HSD11B1 mRNA CTD PMID:17350061 sodium arsenite decreases expression ISO RGD:737091 6480464 sodium arsenite results in decreased expression of HSD11B1 mRNA CTD PMID:29301061 sodium aurothiomalate decreases expression ISO RGD:737091 6480464 Gold Sodium Thiomalate results in decreased expression of HSD11B1 mRNA CTD PMID:19192274 spironolactone multiple interactions ISO RGD:10734 6480464 Spironolactone inhibits the reaction [Corticosterone promotes the reaction [[trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA]] CTD PMID:30993381 sulforaphane multiple interactions ISO RGD:737091 6480464 [HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein], [Mifepristone binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [[HSD11B1 protein results in increased activity of Cortisone] inhibits the reaction [sulforaphane results in increased activity of NFE2L2 protein]] CTD PMID:22606287 taurolithocholic acid increases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in increased abundance of Taurolithocholic Acid CTD PMID:25061560 tauroursodeoxycholic acid decreases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in decreased abundance of ursodoxicoltaurine CTD PMID:25061560 tauroursodeoxycholic acid decreases expression EXP 6480464 ursodoxicoltaurine results in decreased expression of HSD11B1 mRNA CTD PMID:15885361 tauroursodeoxycholic acid multiple interactions EXP 6480464 ursodoxicoltaurine inhibits the reaction [Nicotine results in increased expression of HSD11B1 mRNA] CTD PMID:26803847 tenofovir disoproxil fumarate affects expression ISO RGD:737091 6480464 Tenofovir affects the expression of HSD11B1 mRNA CTD PMID:20032539 tert-butyl hydroperoxide decreases expression ISO RGD:737091 6480464 tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA CTD PMID:29935159 tert-butyl hydroperoxide multiple interactions ISO RGD:737091 6480464 Catechin inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA], Grape Seed Extract inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of HSD11B1 mRNA] CTD PMID:29935159 testosterone increases activity ISO RGD:737091 6480464 Testosterone results in increased activity of HSD11B1 protein CTD PMID:20410225 testosterone multiple interactions ISO RGD:737091 6480464 [Testosterone co-treated with NAD] binds to HSD11B1 protein, Testosterone inhibits the reaction [HSD11B1 protein results in increased reduction of 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone] CTD PMID:25526675 , PMID:28257955 testosterone increases expression ISO RGD:10734 6480464 Testosterone results in increased expression of HSD11B1 mRNA CTD PMID:19693291 testosterone increases expression ISO RGD:737091 6480464 Testosterone results in increased expression of HSD11B1 mRNA CTD PMID:20410225 tetrachloromethane affects expression ISO RGD:10734 6480464 Carbon Tetrachloride affects the expression of HSD11B1 mRNA CTD PMID:17484886 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of HSD11B1 mRNA CTD PMID:31150632 tetrachloromethane decreases expression ISO RGD:10734 6480464 Carbon Tetrachloride results in decreased expression of HSD11B1 mRNA CTD PMID:27339419 , PMID:31919559 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of HSD11B1 mRNA CTD PMID:34492290 titanium dioxide decreases expression ISO RGD:10734 6480464 titanium dioxide results in decreased expression of HSD11B1 mRNA CTD PMID:23557971 titanium dioxide multiple interactions ISO RGD:10734 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HSD11B1 mRNA CTD PMID:29950665 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of HSD11B1 mRNA CTD PMID:25729387 topotecan increases expression EXP 6480464 Topotecan results in increased expression of HSD11B1 mRNA CTD PMID:25729387 triadimefon increases reduction EXP 6480464 HSD11B1 protein results in increased reduction of triadimefon CTD PMID:18763812 trimethyltin multiple interactions ISO RGD:10734 6480464 1 more ... CTD PMID:30993381 trimethyltin multiple interactions EXP 6480464 [trimethyltin chloride results in increased abundance of trimethyltin] which results in increased expression of HSD11B1 mRNA more ... CTD PMID:30993381 triphenylstannane multiple interactions EXP 6480464 [triphenyltin co-treated with ethylene dimethanesulfonate] affects the expression of HSD11B1 mRNA, [triphenyltin co-treated with ethylene dimethanesulfonate] affects the expression of HSD11B1 protein CTD PMID:30772500 triphenylstannane decreases expression EXP 6480464 triphenyltin results in decreased expression of HSD11B1 mRNA, triphenyltin results in decreased expression of HSD11B1 protein CTD PMID:31765896 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of HSD11B1 mRNA CTD PMID:14697232 troglitazone increases expression ISO RGD:737091 6480464 troglitazone results in increased expression of HSD11B1 mRNA CTD PMID:25572481 ursodeoxycholic acid multiple interactions ISO RGD:737091 6480464 [HSD11B1 protein results in increased reduction of 7-ketolithocholic acid] which results in increased chemical synthesis of Ursodeoxycholic Acid CTD PMID:21453287 ursodeoxycholic acid increases abundance ISO RGD:10734 6480464 HSD11B1 gene mutant form results in increased abundance of Ursodeoxycholic Acid CTD PMID:25061560 valproic acid increases expression ISO RGD:737091 6480464 Valproic Acid results in increased expression of HSD11B1 mRNA CTD PMID:28001369 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of HSD11B1 mRNA CTD PMID:19015723 vitamin E increases expression ISO RGD:737091 6480464 Vitamin E results in increased expression of HSD11B1 mRNA CTD PMID:19244175 zearalenone decreases expression EXP 6480464 Zearalenone results in decreased expression of HSD11B1 mRNA, Zearalenone results in decreased expression of HSD11B1 protein CTD PMID:29669061 zidovudine affects expression ISO RGD:737091 6480464 Zidovudine affects the expression of HSD11B1 mRNA CTD PMID:20032539 zinc protoporphyrin multiple interactions ISO RGD:10734 6480464 zinc protoporphyrin inhibits the reaction [2-(3-benzoyl)-4-hydroxy-1 more ... CTD PMID:27523796 zinc sulfate decreases expression ISO RGD:737091 6480464 Zinc Sulfate results in decreased expression of HSD11B1 mRNA CTD PMID:12756304 ziram decreases expression EXP 6480464 Ziram results in decreased expression of HSD11B1 mRNA, Ziram results in decreased expression of HSD11B1 protein CTD PMID:28973382 ziram multiple interactions EXP 6480464 Ziram inhibits the reaction [[HSD11B1 protein results in increased reduction of 11-dehydrocorticosterone] which results in increased chemical synthesis of Corticosterone] more ... CTD PMID:26859423 ziram decreases activity EXP 6480464 Ziram results in decreased activity of HSD11B1 protein CTD PMID:26859423 zoledronic acid increases expression ISO RGD:737091 6480464 zoledronic acid results in increased expression of HSD11B1 mRNA CTD PMID:24714768
