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Gene: Il12rb1 (interleukin 12 receptor subunit beta 1) Rattus norvegicus
Symbol: Il12rb1
Name: interleukin 12 receptor subunit beta 1
RGD ID: 620025
Description: Predicted to contribute to cytokine receptor activity; interleukin-12 receptor binding activity; and interleukin-23 binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; positive regulation of activated T cell proliferation; and positive regulation of defense response to virus by host. Predicted to localize to external side of plasma membrane; interleukin-12 receptor complex; and interleukin-23 receptor complex. Biomarker of primary biliary cholangitis. Human ortholog(s) of this gene implicated in immunodeficiency 30. Orthologous to human IL12RB1 (interleukin 12 receptor subunit beta 1); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; INTERACTS WITH acetamide; ammonium chloride; bisphenol A.
Type: protein-coding
Also known as: Il12rb; interleukin 12 receptor, beta 1; interleukin-12 receptor subunit beta-1
Homo sapiens (human) : IL12RB1 (interleukin 12 receptor subunit beta 1)  HGNC  Alliance
Mus musculus (house mouse) : Il12rb1 (interleukin 12 receptor, beta 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Canis lupus familiaris (dog) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Sus scrofa (pig) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Chlorocebus sabaeus (African green monkey) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Il12rb1 (interleukin 12 receptor subunit beta 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01620,370,722 - 20,383,576 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,371,338 - 20,383,337 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,227,894 - 20,240,670 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,126,653 - 19,137,584 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11619,126,957 - 19,128,305 (-)NCBI
Celera1618,812,772 - 18,825,080 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Il12rb1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620025
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.