Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Il12rb1 (interleukin 12 receptor, beta 1) Mus musculus
Analyze
Symbol: Il12rb1
Name: interleukin 12 receptor, beta 1
Description: Contributes to cytokine binding activity. Involved in peptidyl-tyrosine phosphorylation. Localizes to the external side of plasma membrane and interleukin-23 receptor complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in mandible; maxilla; orbito-sphenoid; rib; and testis. Orthologous to human IL12RB1 (interleukin 12 receptor subunit beta 1); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD212; IL-12 receptor beta component; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12R[b]; Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component); interleukin-12 receptor subunit beta-1
Orthologs:
Homo sapiens (human) : IL12RB1 (interleukin 12 receptor subunit beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il12rb1 (interleukin 12 receptor subunit beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Canis lupus familiaris (dog) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Sus scrofa (pig) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Chlorocebus sabaeus (African green monkey) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Il12rb1 (interleukin 12 receptor subunit beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl870,808,449 - 70,821,424 (+)Ensembl
GRCm38870,808,360 - 70,823,542 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37873,332,348 - 73,345,323 (+)NCBIGRCm37mm9NCBIm37
MGSCv36873,737,483 - 73,750,411 (+)NCBImm8
Celera873,369,767 - 73,382,761 (+)NCBICelera
Cytogenetic Map8 B3.3NCBI
cM Map834.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Il12rb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550152
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.