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Gene: Il12rb1 (interleukin 12 receptor, beta 1) Mus musculus
Symbol: Il12rb1
Name: interleukin 12 receptor, beta 1
Description: Contributes to cytokine binding activity. Involved in peptidyl-tyrosine phosphorylation. Localizes to the external side of plasma membrane and interleukin-23 receptor complex. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Is expressed in mandible; maxilla; orbito-sphenoid; rib; and testis. Orthologous to human IL12RB1 (interleukin 12 receptor subunit beta 1); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; interleukin-27 signaling pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CD212; IL-12 receptor beta component; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12R[b]; Interleukin-12 receptor beta-1 chain precursor (IL-12R-beta1) (Interleukin-12 receptor beta) (IL-12 receptor beta component); interleukin-12 receptor subunit beta-1
Homo sapiens (human) : IL12RB1 (interleukin 12 receptor subunit beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il12rb1 (interleukin 12 receptor subunit beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Canis lupus familiaris (dog) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il12rb1 (interleukin 12 receptor subunit beta 1)
Sus scrofa (pig) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Chlorocebus sabaeus (African green monkey) : IL12RB1 (interleukin 12 receptor subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Il12rb1 (interleukin 12 receptor subunit beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl870,808,449 - 70,821,424 (+)Ensembl
GRCm38870,808,360 - 70,823,542 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37873,332,348 - 73,345,323 (+)NCBIGRCm37mm9NCBIm37
MGSCv36873,737,483 - 73,750,411 (+)NCBImm8
Celera873,369,767 - 73,382,761 (+)NCBICelera
Cytogenetic Map8 B3.3NCBI
cM Map834.21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il12rb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1550152
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.