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Gene: Dhodh (dihydroorotate dehydrogenase (quinone)) Rattus norvegicus
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Symbol: Dhodh
Name: dihydroorotate dehydrogenase (quinone)
Description: Exhibits several functions, including FMN binding activity; dihydroorotate dehydrogenase activity; and ubiquinone binding activity. Involved in several processes, including 'de novo' pyrimidine nucleobase biosynthetic process; lactation; and response to L-arginine. Localizes to the mitochondrial inner membrane and neuronal cell body. Orthologous to human DHODH (dihydroorotate dehydrogenase (quinone)); PARTICIPATES IN beta-ureidopropionase deficiency pathway; de novo pyrimidine biosynthetic pathway; dihydropyrimidinase deficiency pathway; INTERACTS WITH 1,4-naphthoquinone; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DHOdehase; dihydroorotate dehydrogenase; dihydroorotate dehydrogenase (quinone), mitochondrial; dihydroorotate dehydrogenase, mitochondrial; dihydroorotate oxidase
Orthologs:
Homo sapiens (human) : DHODH (dihydroorotate dehydrogenase (quinone))  HGNC  Alliance
Mus musculus (house mouse) : Dhodh (dihydroorotate dehydrogenase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dhodh (dihydroorotate dehydrogenase (quinone))
Pan paniscus (bonobo/pygmy chimpanzee) : DHODH (dihydroorotate dehydrogenase (quinone))
Canis lupus familiaris (dog) : DHODH (dihydroorotate dehydrogenase (quinone))
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dhodh (dihydroorotate dehydrogenase (quinone))
Sus scrofa (pig) : DHODH (dihydroorotate dehydrogenase (quinone))
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01942,066,103 - 42,087,906 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01952,891,853 - 52,913,708 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41939,463,111 - 39,477,184 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11939,467,991 - 39,482,059 (-)NCBI
Celera1936,964,203 - 36,978,276 (-)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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More on Dhodh
Alliance Gene
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JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 68352
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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