Gene: Mark1 (microtubule affinity regulating kinase 1) Rattus norvegicus
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Symbol: Mark1
Name: microtubule affinity regulating kinase 1
Description: ENCODES a protein that exhibits ATP binding; magnesium ion binding; protein kinase activity; INVOLVED IN cytoskeleton organization; intracellular signal transduction; microtubule cytoskeleton organization; ASSOCIATED WITH autistic disorder (ortholog); Loeys-Dietz syndrome 4 (ortholog); Stomach Neoplasms (ortholog); FOUND IN cytoplasm; cytoskeleton; dendrite (ortholog); INTERACTS WITH ammonium chloride; bexarotene; bisphenol A
AGR Description: Exhibits ATP binding activity, magnesium ion binding activity, and protein kinase activity; involved in several processes, including intracellular signal transduction, microtubule cytoskeleton organization, and neuron migration; localizes to the cytoplasm and cytoskeleton; orthologous to human MARK1 (microtubule affinity regulating kinase 1).
Merged Description: Exhibits ATP binding activity, magnesium ion binding activity, and protein kinase activity; involved in several processes, including intracellular signal transduction, microtubule cytoskeleton organization, and neuron migration; localizes to the cytoplasm and cytoskeleton; orthologous to human MARK1 (microtubule affinity regulating kinase 1); INTERACTS WITH ammonium chloride; bexarotene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MAP/microtubule affinity-regulating kinase 1; serine/threonine-protein kinase MARK1
Orthologs:
Homo sapiens (human) : MARK1 (microtubule affinity regulating kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mark1 (MAP/microtubule affinity regulating kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mark1 (microtubule affinity regulating kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MARK1 (microtubule affinity regulating kinase 1)
Canis lupus familiaris (dog) : MARK1 (microtubule affinity regulating kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mark1 (microtubule affinity regulating kinase 1)
Sus scrofa (pig) : MARK1 (microtubule affinity regulating kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013102,808,254 - 102,942,863 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013107,485,344 - 107,589,704 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413100,905,369 - 101,009,161 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113101,094,411 - 101,198,263 (-)NCBI
Celera1395,968,489 - 96,018,212 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Mark1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 619882
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.