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Gene: Pthlh (parathyroid hormone-like hormone) Rattus norvegicus
Symbol: Pthlh
Name: parathyroid hormone-like hormone
RGD ID: 3441
Description: Exhibits hormone activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to localize to Golgi apparatus; cytosol; and nucleoplasm. Human ortholog(s) of this gene implicated in brachydactyly type E2. Orthologous to human PTHLH (parathyroid hormone like hormone); PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: parathyroid hormone-like peptide; parathyroid hormone-like protein; parathyroid hormone-related protein; parathyroid-like peptide; PLP; PTH-rP; PTHrP
Homo sapiens (human) : PTHLH (parathyroid hormone like hormone)  HGNC  Alliance
Mus musculus (house mouse) : Pthlh (parathyroid hormone-like peptide)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pthlh (parathyroid hormone like hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : PTHLH (parathyroid hormone like hormone)
Canis lupus familiaris (dog) : PTHLH (parathyroid hormone like hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pthlh (parathyroid hormone like hormone)
Sus scrofa (pig) : PTHLH (parathyroid hormone like hormone)
Chlorocebus sabaeus (African green monkey) : PTHLH (parathyroid hormone like hormone)
Heterocephalus glaber (naked mole-rat) : Pthlh (parathyroid hormone like hormone)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04181,663,425 - 181,674,181 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04245,811,895 - 245,822,651 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44184,887,702 - 184,898,841 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14185,132,825 - 185,143,965 (-)NCBI
Celera4168,675,915 - 168,686,473 (-)NCBICelera
Cytogenetic Map4q44NCBI
RH 3.4 Map41091.1RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)



Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pthlh
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3441
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.