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Gene: Pthlh (parathyroid hormone-like peptide) Mus musculus
Symbol: Pthlh
Name: parathyroid hormone-like peptide
Description: Predicted to have hormone activity and peptide hormone receptor binding activity. Involved in several processes, including animal organ development; osteoblast development; and surfactant homeostasis. Predicted to localize to the Golgi apparatus; cytosol; and nucleoplasm. Used to study Albright's hereditary osteodystrophy and achondroplasia. Human ortholog(s) of this gene implicated in brachydactyly type E2. Is expressed in several structures, including brain; integumental system; limb; sensory organ; and skeletal system. Orthologous to human PTHLH (parathyroid hormone like hormone).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: parathyroid hormone-like hormone; parathyroid hormone-like protein; parathyroid hormone-related peptide; parathyroid hormone-related protein; PLP; PTH-like; PTH-related peptide; PTH-rP; Pthrp
Homo sapiens (human) : PTHLH (parathyroid hormone like hormone)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pthlh (parathyroid hormone-like hormone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pthlh (parathyroid hormone like hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : PTHLH (parathyroid hormone like hormone)
Canis lupus familiaris (dog) : PTHLH (parathyroid hormone like hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pthlh (parathyroid hormone like hormone)
Sus scrofa (pig) : PTHLH (parathyroid hormone like hormone)
Chlorocebus sabaeus (green monkey) : PTHLH (parathyroid hormone like hormone)
Heterocephalus glaber (naked mole-rat) : Pthlh (parathyroid hormone like hormone)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl6147,252,101 - 147,264,183 (-)Ensembl
GRCm386147,252,109 - 147,264,013 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376147,200,632 - 147,212,607 (-)NCBIGRCm37mm9NCBIm37
MGSCv366147,209,270 - 147,221,371 (-)NCBImm8
Celera6150,289,180 - 150,301,102 (-)NCBICelera
Cytogenetic Map6 G3NCBI
cM Map678.19NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pthlh
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11188
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.