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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3441
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pthlh
Name: parathyroid hormone-like hormone
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pthlhincreases expressionEXP 6480464CTDCadmium Chloride results in increased expression of PTHLH mRNAPMID:23750309
Pthlhmultiple interactionsEXP 6480464CTD[sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in decreased expression of PTHLH protein; Telmisartan inhibits the reaction [Cadmium Chloride results in increased expression of PTHLH protein]PMID:23604592 PMID:23750309
Pthlhincreases expressionISOPTHLH (Homo sapiens)6480464CTDCadmium Chloride results in increased expression of PTHLH mRNAPMID:38568856
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