GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pthlh | increases expression | EXP | | 6480464 | CTD | Folic Acid results in increased expression of PTHLH mRNA; Folic Acid results in increased expression of PTHLH protein | PMID:11532093 PMID:15728788 | Pthlh | multiple interactions | EXP | | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Folic Acid results in increased expression of PTHLH protein]; [Folic Acid results in increased activity of MAPK1 protein] which results in increased expression of PTHLH protein; [Folic Acid results in increased activity of MAPK3 protein] which results in increased expression of PTHLH protein; AGT protein promotes the reaction [Folic Acid results in increased expression of PTHLH protein]; CREB1 protein promotes the reaction [Folic Acid results in increased expression of PTHLH mRNA]; Enalapril inhibits the reaction [Folic Acid results in increased expression of PTHLH mRNA]; Enalapril inhibits the reaction [Folic Acid results in increased expression of PTHLH protein]; Losartan inhibits the reaction [Folic Acid results in increased expression of PTHLH mRNA]; Losartan inhibits the reaction [Folic Acid results in increased expression of PTHLH protein]; PTHLH protein promotes the reaction [Folic Acid results in increased expression of AGT protein]; quinapril inhibits the reaction [Folic Acid results in increased expression of PTHLH mRNA]; quinapril inhibits the reaction [Folic Acid results in increased expression of PTHLH protein] | PMID:15728788 | Pthlh | decreases expression | ISO | Pthlh (Mus musculus) | 6480464 | CTD | Folic Acid results in decreased expression of PTHLH mRNA | PMID:25629700 | Pthlh | multiple interactions | ISO | Pthlh (Mus musculus) | 6480464 | CTD | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of PTHLH mRNA]; PTHLH protein inhibits the reaction [Folic Acid results in increased expression of BAX protein]; PTHLH protein inhibits the reaction [Folic Acid results in increased expression of BCL2 protein] | PMID:16672315 PMID:22206623 | |
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